MCID: INH006
MIFTS: 15

Inherited Peripheral Neuropathy malady

Neuronal category

Summaries for Inherited Peripheral Neuropathy

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33MalaCards
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MalaCards: Inherited Peripheral Neuropathy is related to tooth disease and arthritis. An important gene associated with Inherited Peripheral Neuropathy is GJB1 (gap junction protein, beta 1, 32kDa), and among its related pathways is Neural Crest Differentiation. The compounds ganglioside and dihydroprogesterone have been mentioned in the context of this disorder. Related mouse phenotypes are behavior/neurological and mortality/aging.

Aliases & Classifications for Inherited Peripheral Neuropathy

Sources:
43NIH Rare Diseases, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

inherited peripheral neuropathy 43 61


Related Diseases for Inherited Peripheral Neuropathy

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Inherited Peripheral Neuropathy:



Diseases related to inherited peripheral neuropathy

Clinical Features for Inherited Peripheral Neuropathy

Drugs & Therapeutics for Inherited Peripheral Neuropathy

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Inherited Peripheral Neuropathy

Drug clinical trials:

Search ClinicalTrials for Inherited Peripheral Neuropathy

Search NIH Clinical Center for Inherited Peripheral Neuropathy

Search CenterWatch for Inherited Peripheral Neuropathy

Genetic Tests for Inherited Peripheral Neuropathy

Anatomical Context for Inherited Peripheral Neuropathy

Animal Models for Inherited Peripheral Neuropathy or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Inherited Peripheral Neuropathy:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.4GJB1, CNTNAP1, MPZ, EGR2, PMP22
2MP:00107687.5GJB1, PMP22, HSPB8, EGR2, MPZ, CNTNAP1

Publications for Inherited Peripheral Neuropathy

Sources:
51PubMed
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Articles related to Inherited Peripheral Neuropathy:

idTitleAuthorsYear
1
Pupil abnormalities in 131 cases of genetically defined inherited peripheral neuropathy. (18636082)
2009
2
Inherited peripheral neuropathy. (10716658)
1999
3
Joint sparing in a rheumatoid arthritis patient with an inherited peripheral neuropathy. (8869228)
1995
4
An inherited DNA rearrangement and gene dosage effect are responsible for the most common autosomal dominant peripheral neuropathy: Charcot-Marie-Tooth disease type 1A. (1486731)
1992
5
Charcot-Marie-Tooth disease type 1A: molecular mechanisms of gene dosage and point mutation underlying a common inherited peripheral neuropathy. (11980069)
1991-1992

Genetic Variations for Inherited Peripheral Neuropathy

Expression for genes affiliated with Inherited Peripheral Neuropathy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Inherited Peripheral Neuropathy

Search GEO for disease gene expression data for Inherited Peripheral Neuropathy.

Pathways for genes affiliated with Inherited Peripheral Neuropathy

Sources:
38NCBI BioSystems Database
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Pathways related to Inherited Peripheral Neuropathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7GJB1, MPZ

Compounds for genes affiliated with Inherited Peripheral Neuropathy

Sources:
45Novoseek
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Compounds related to Inherited Peripheral Neuropathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1ganglioside459.7MPZ, PMP22
2dihydroprogesterone459.4MPZ, PMP22

GO Terms for genes affiliated with Inherited Peripheral Neuropathy

Sources:
16Gene Ontology
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Biological processes related to Inherited Peripheral Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peripheral nervous system developmentGO:0074229.6EGR2, PMP22

Products for genes affiliated with Inherited Peripheral Neuropathy

  • Antibodies
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Sources for Inherited Peripheral Neuropathy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet