MCID: INT093
MIFTS: 21

Interferon Gamma, Receptor 1, Deficiency malady

Summaries for Interferon Gamma, Receptor 1, Deficiency

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MalaCards: Interferon Gamma, Receptor 1, Deficiency, also known as ifngr1 deficiency, is related to osteomyelitis and tuberculosis. An important gene associated with Interferon Gamma, Receptor 1, Deficiency is IFNGR1 (interferon gamma receptor 1), and among its related pathways are Interferon Pathway and Toll Comparative Pathway. The compounds tuberculin and okt3 have been mentioned in the context of this disorder. Related mouse phenotypes are digestive/alimentary and endocrine/exocrine gland.

Aliases & Classifications for Interferon Gamma, Receptor 1, Deficiency

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42NIH Rare Diseases
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Aliases & Descriptions:

interferon gamma, receptor 1, deficiency 42
ifngr1 deficiency 42


Related Diseases for Interferon Gamma, Receptor 1, Deficiency

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Interferon Gamma, Receptor 1, Deficiency:



Diseases related to interferon gamma, receptor 1, deficiency

Clinical Features for Interferon Gamma, Receptor 1, Deficiency

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Drugs & Therapeutics for Interferon Gamma, Receptor 1, Deficiency

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Interferon Gamma, Receptor 1, Deficiency

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Genetic Tests for Interferon Gamma, Receptor 1, Deficiency

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Anatomical Context for Interferon Gamma, Receptor 1, Deficiency

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Animal Models for Interferon Gamma, Receptor 1, Deficiency or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Interferon Gamma, Receptor 1, Deficiency:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6LBR, IFNGR1, IFNG
2MP:00053798.5LBR, IFNGR1, IFNG
3MP:00053898.5LBR, IFNGR1, IFNG
4MP:00053908.4IFNG, IFNGR1, LBR
5MP:00107718.2LBR, IFNGR1, IFNG

Publications for Interferon Gamma, Receptor 1, Deficiency

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Genetic Variations for Interferon Gamma, Receptor 1, Deficiency

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Expression for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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Pathways for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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51QIAGEN, 12EMD Millipore, 29KEGG, 37NCBI BioSystems Database, 53Reactome, 52R&D Systems
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Pathways related to Interferon Gamma, Receptor 1, Deficiency according to GeneCards/GeneDecks:

(show all 18)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3IFNG, IFNGR1
2
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9.3IFNG, IFNGR1
39.3IFNG, IFNGR1
4
Immune response Bacterial infections in normal airways
9.3IFNG, IFNGR1
59.3IFNGR1, IFNG
6
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9.3IFNGR1, IFNG
79.3IFNGR1, IFNG
8
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9.3IFNGR1, IFNG
9
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9.3IFNGR1, IFNG
109.3IFNGR1, IFNG
119.3IFNGR1, IFNG
129.3IFNGR1, IFNG
13
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9.3IFNGR1, IFNG
14
Hide members
9.3IFNGR1, IFNG
15
Immune response IFN gamma signaling pathway
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9.3IFNGR1, IFNG
169.3IFNGR1, IFNG
179.3IFNGR1, IFNG
18
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9.3IFNGR1, IFNG

Compounds for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Interferon Gamma, Receptor 1, Deficiency according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tuberculin449.4LBR, IFNG
2okt3449.3LBR, IFNG
3con a449.3IFNG, LBR
4infliximab44 49 1111.2LBR, IFNG
5ribavirin44 49 1111.2IFNG, LBR
6deferoxamine44 1110.2LBR, IFNGR1
7pentoxifylline44 1110.1LBR, IFNG
8rantes449.1LBR, IFNG
9neopterin449.0LBR, IFNG
10ionomycin448.8LBR, IFNG

GO Terms for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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16Gene Ontology
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Biological processes related to Interferon Gamma, Receptor 1, Deficiency according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of interferon-gamma-mediated signaling pathwayGO:0603349.3IFNGR1, IFNG
2cytokine-mediated signaling pathwayGO:0192219.3IFNGR1, IFNG
3interferon-gamma-mediated signaling pathwayGO:0603339.2IFNGR1, IFNG
4response to virusGO:0096159.0IFNGR1, IFNG

Products for genes affiliated with Interferon Gamma, Receptor 1, Deficiency

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  • Antibodies
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  • Lysates
  • Antibodies

Sources for Interferon Gamma, Receptor 1, Deficiency

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet