Interleukin 2 Receptor Alpha Chain Deficiency malady

MalaCards: Interleukin 2 Receptor Alpha Chain Deficiency, also known as interleukin-2 receptor, alpha chain, deficiency of, is related to protein-energy malnutrition and ancylostomiasis. An important gene associated with Interleukin 2 Receptor Alpha Chain Deficiency is IL2RA (interleukin 2 receptor, alpha).

OMIM: 606367

interleukin 2 receptor alpha chain deficiency 16 interleukin-2 receptor, alpha chain, deficiency of 33

malnutrition 43

Diseases related to interleukin 2 receptor alpha chain deficiency by text searches and GeneDecks gene sharing:

(show top 50)    (show all 130)

id	Related Disease	Score	Top Affiliating Genes
1	protein-energy malnutrition	8.9
2	ancylostomiasis	5.1
3	marasmus	5.1
4	nutritional deficiency disease	5.1
5	17-beta-hydroxysteroid dehydrogenase x deficiency	4.2
6	ariboflavinosis	4.2
7	c1q deficiency, type b	4.2
8	cholestasis, progressive familial intrahepatic 1	4.2
9	cpt deficiency, hepatic, type ii	4.2
10	deficiency of interleukin-1 receptor antagonist	4.2
11	gtp cyclohydrolase 1-deficient dopa-responsive dystonia	4.2
12	methylcobalamin deficiency	4.2
13	17β-hydroxysteroid dehydrogenase type 10 deficiency	4.2
14	alcoholic liver cirrhosis	4.2
15	cpt ii deficiency, lethal neonatal	4.2
16	fucosyltransferase deficiency	4.2
17	gtp cyclohydrolase 1 deficiency (gtpch)	4.2
18	methylcobalamin deficiency cbl g type	4.2
19	phosphomannoisomerase deficiency	4.2
20	preaxial deficiency, postaxial polydactyly and hypospadias	4.2
21	sucla2-related mitochondrial dna depletion syndrome, encephalomyopathic form, with mild methylmalonic aciduria	4.2
22	transcobalamin 1 deficiency	4.2
23	ala dehydratase deficiency	4.2
24	c4 deficiency	4.2
25	cr1 deficiency	4.2
26	fucosyltransferase-6 deficiency	4.2
27	glutamine deficiency, congenital	4.2
28	hdl deficiency	4.2
29	hypolipoproteinemia	4.2
30	kininogen deficiency	4.2
31	methylcobalamin deficiency, cbl e complementation type	4.2
32	transverse limb deficiency hemangioma	4.2
33	ala deficiency porphyria	4.2
34	c8 deficiency	4.2
35	glycogen storage disease ix	4.2
36	hmg-coa synthase deficiency	4.2
37	n-acetyl-alpha-d-galactosaminidase deficiency type iii	4.2
38	placental lactogen deficiency	4.2
39	psph deficiency	4.2
40	selective igg deficiency disease	4.2
41	dna ligase iv deficiency	4.2
42	hmg-coa synthase-2 deficiency	4.2
43	plasmalogens synthesis deficiency isolated	4.2
44	alpha-antichymotrypsin deficiency	4.2
45	cblg	4.2
46	dna ligase i deficiency	4.2
47	lactate dehydrogenase deficiency	4.2
48	platelet plc beta deficiency	4.2
49	tyrosine hydroxylase deficiency	4.2
50	3-hydroxyisobutryl-coa hydrolase deficiency	4.2

Clinical features from OMIM: 606367

Approved drugs:

Drug clinical trials:

Genetic tests related to interleukin 2 receptor alpha chain deficiency:

id	Genetic test	Affiliating Genes
1	Interleukin 2 Receptor Alpha Chain Deficiency clinical/research	IL2RA

Genes related to interleukin 2 receptor alpha chain deficiency according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	IL2RA	interleukin 2 receptor, alpha	11.1	Disorders