MCID: INT007
MIFTS: 50

Intermediate Coronary Syndrome malady

Categories: Cardiovascular diseases, Cancer diseases

Aliases & Classifications for Intermediate Coronary Syndrome

Aliases & Descriptions for Intermediate Coronary Syndrome:

Name: Intermediate Coronary Syndrome 12 14
Angina, Unstable 42 69
Unstable Angina 12 14
Myocardial Preinfarction Syndrome 69
Carcinoma in Situ of Trachea 69
Tracheal Carcinoma in Situ 12
Anginal Chest Pain at Rest 12
Impending Infarction 12
Preinfarction Angina 12
Worsening Angina 12
Angina at Rest 12

Classifications:



Summaries for Intermediate Coronary Syndrome

MalaCards based summary : Intermediate Coronary Syndrome, also known as angina, unstable, is related to myocardial infarction and prinzmetal's variant angina, and has symptoms including angina pectoris, coughing and dyspnea. An important gene associated with Intermediate Coronary Syndrome is ITGA2B (Integrin Subunit Alpha 2b), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Heparin and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include trachea and lung, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Intermediate Coronary Syndrome

Diseases related to Intermediate Coronary Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 27.4 ACE CRP F3 IL6 ITGA2B MB
2 prinzmetal's variant angina 11.5
3 coronary artery disease 11.4
4 trachea carcinoma in situ 11.1
5 isolated brachycephaly 10.3 TNNI3 TNNT2
6 colonic lymphangioma 10.3 ACE ITGA2B
7 iron metabolism disease 10.3 ACE CRP
8 sertoli cell tumor 10.2 F3 SERPINC1
9 influenza 10.2 F3 SERPINC1
10 glomerulonephritis 10.2 MB TNNI3 TNNT2
11 carbohydrate metabolic disorder 10.2 ACE SERPINC1
12 freiberg's disease 10.2 F3 SERPINC1
13 midline cystocele 10.2 CRP F3 SERPINC1
14 myositis fibrosa 10.2 SERPINC1 TNNI3 TNNT2
15 hypertrophic elongation of cervix 10.2 ACE CRP ITGA2B
16 intestinal disaccharidase deficiency 10.2 CRP F3 SERPINC1
17 ostertagiasis 10.2 TNNI3 TNNT1 TNNT2
18 pancreatic ductal carcinoma 10.2 F3 SERPINC1
19 subclavian artery aneurysm 10.2 F3 ITGA2B SELP
20 coloboma of iris 10.2 CRP IL6
21 pervasive developmental disorder 10.2 ACE TNNI3 TNNT2
22 hereditary endotheliopathy, retinopathy, nephropathy, and stroke 10.2 F3 SELP SERPINC1
23 pyelonephritis 10.2 ACE CRP SERPINC1
24 anogenital venereal wart 10.1 ACE CRP F3
25 microscopic breast papilloma 10.1 ACE MB TNNI3
26 voyeurism 10.1 MB PLAT TNNI3
27 inferolateral myocardial infarct 10.1 ACE ITGA2B PLAT
28 cutaneous sclerosis 10.1 CRP IL6
29 intra-abdominal lymph node mast cell malignancy 10.1 ACE CRP SELP
30 ductal carcinoma in situ 10.1 F3 PLAT SERPINC1
31 zika virus congenital syndrome 10.1 F3 PLAT SERPINC1
32 shoulder impingement syndrome 10.1 CRP IL6
33 mixed hepatoblastoma 10.1 F3 SERPINC1
34 alcoholic gastritis 10.1 F3 PLAT SERPINC1
35 testicular lymphoma 10.1 ACE CRP SELP
36 brazilian hemorrhagic fever 10.1 PLAT SERPINC1
37 autoimmune disease of central nervous system 10.1 CRP IL6 TNNI3
38 multiple mitochondrial dysfunctions syndrome 10.1 CRP F3 IL6
39 melorheostosis 10.1 ACE PLAT SERPINC1
40 pancreas lymphoma 10.1 CRP IL6 TNNT2
41 chorioretinal scar 10.1 F3 SERPINC1
42 joint disorders 10.1 ACE CRP IL6
43 toxic myocarditis 10.1 ACE CRP IL6
44 long qt syndrome 9 10.1 ACE TNNI3 TNNT1 TNNT2
45 hereditary alpha tryptasemia syndrome 10.1 F3 IL6 SERPINC1
46 tuberculosis 10.1 ACE IL6 TNNI3
47 gait apraxia 10.0 ACE CRP IL6
48 choroiditis 10.0 ACE CRP IL6
49 unilateral multicystic dysplastic kidney 10.0 CRP IL6 PLAT
50 spinal multifocal clear cell meningioma 10.0 F3 IL6 SERPINC1

Comorbidity relations with Intermediate Coronary Syndrome via Phenotypic Disease Network (PDN): (show top 50) (show all 103)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Kidney Failure
Acute Myocardial Infarction Acute Stress Disorder
Allergic Urticaria Anthracosis
Anxiety Disorder Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 2
Asbestosis Atrioventricular Block
Atrophic Gastritis Basilar Artery Insufficiency
Benign Essential Hypertension Benign Hypertensive Renal Disease
Benign Paroxysmal Positional Nystagmus Bleeding Disorder, Platelet-Type, 11
Bronchitis Cardiac Arrest
Cardiogenic Shock Cardiomyopathy, Familial Hypertrophic
Cerebrovascular Disease Chronic Kidney Failure
Chronic Myocardial Ischemia Constrictive Pericarditis
Deficiency Anemia Diabetic Polyneuropathy
Diaphragm Disease Dressler's Syndrome
Duodenitis Dyskinesia of Esophagus
Dysthymic Disorder Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Gallbladder Disease Gastroesophageal Reflux
Generalized Atherosclerosis Gout
Heart Conduction Disease Heart Disease
Hemopericardium Hyperlipidemia, Familial Combined
Hyperlipoproteinemia Type Iv Hypertension, Essential
Hypertensive Encephalopathy Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis

Graphical network of the top 20 diseases related to Intermediate Coronary Syndrome:



Diseases related to Intermediate Coronary Syndrome

Symptoms & Phenotypes for Intermediate Coronary Syndrome

UMLS symptoms related to Intermediate Coronary Syndrome:


angina pectoris, coughing, dyspnea, hemoptysis, hoarseness

MGI Mouse Phenotypes related to Intermediate Coronary Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.18 ACE CRP F3 IL6 ITGA2B MB
2 homeostasis/metabolism MP:0005376 10.07 ACE CRP F3 IL6 ITGA2B MB
3 hematopoietic system MP:0005397 10.06 IL6 ITGA2B MB P2RY12 PLAT SELP
4 immune system MP:0005387 9.81 ACE CRP F3 IL6 ITGA2B PLAT
5 muscle MP:0005369 9.5 F3 IL6 MB PLAT TNNI3 TNNT1
6 respiratory system MP:0005388 9.1 PLAT SELP TNNI3 F3 IL6 MB

Drugs & Therapeutics for Intermediate Coronary Syndrome

Drugs for Intermediate Coronary Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 732)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
2
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
3
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Early Phase 1 10102-43-9 145068
4
Pravastatin Approved Phase 4,Phase 3,Phase 1 81093-37-0 54687
5
Simvastatin Approved Phase 4,Phase 2,Phase 3,Phase 1 79902-63-9 54454
6
Zinc Approved Phase 4,Phase 3,Phase 1 7440-66-6 32051 23994
7
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
8
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 1 50-28-2 5757 53477783
9
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2 33069-62-4 36314
10
Colchicine Approved Phase 4,Phase 3 64-86-8 6167 2833
11
Pantoprazole Approved Phase 4 102625-70-7 4679
12
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
13
Nicorandil Approved Phase 4 65141-46-0 47528
14
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
15
Hydrochlorothiazide Approved, Vet_approved Phase 4 58-93-5 3639
16
Amlodipine Approved Phase 4,Phase 2,Phase 1 88150-42-9 2162
17
Isosorbide Dinitrate Approved Phase 4,Early Phase 1 87-33-2 6883
18
Warfarin Approved Phase 4,Phase 3 81-81-2 6691 54678486
19
Etanercept Approved, Investigational Phase 4,Phase 1,Phase 2 185243-69-0
20
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
21
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
22
Iloprost Approved, Investigational Phase 4 78919-13-8 6443959
23
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 3 58-61-7 60961
24
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
25
Citalopram Approved Phase 4,Phase 1,Phase 2 59729-33-8 2771
26
Everolimus Approved Phase 4,Phase 2,Phase 3 159351-69-6 6442177
27
Methadone Approved Phase 4,Phase 1 76-99-3 4095
28
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
29
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
30
Menthol Approved Phase 4,Phase 2,Phase 1 2216-51-5 16666
31
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
32
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
33
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
34
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3 53123-88-9 5284616 6436030 46835353
35
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
36
Guaifenesin Approved, Vet_approved Phase 4,Phase 1 93-14-1 3516
37
Norepinephrine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-41-2 439260
38
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3 50-02-2 5743
39
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
40
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
41
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
42
Testosterone Approved, Investigational Phase 4 58-22-0 6013
43
Ritonavir Approved, Investigational Phase 4,Phase 1 155213-67-5 392622
44
Lopinavir Approved Phase 4 192725-17-0 92727
45
Efavirenz Approved, Investigational Phase 4,Phase 1 154598-52-4 64139
46
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
47
Nevirapine Approved Phase 4,Phase 1 129618-40-2 4463
48
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
49
Fluvastatin Approved Phase 4,Phase 3,Phase 2 93957-54-1 1548972
50
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033

Interventional clinical trials:

(show top 50) (show all 1275)
id Name Status NCT ID Phase
1 Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes Unknown status NCT00222352 Phase 4
2 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
3 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4
4 Efficacy Study of Nicorandil on Neointima Unknown status NCT02328521 Phase 4
5 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4
6 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
7 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4
8 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
9 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4
10 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4
11 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4
12 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4
13 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4
14 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4
15 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4
16 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
17 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4
18 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4
19 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4
20 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
21 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4
22 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4
23 Efficacy Study of Atorvastatin to Treat Variant Angina Unknown status NCT00620204 Phase 4
24 The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm Unknown status NCT01674686 Phase 4
25 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
26 The Effect of Reloading Prasugrel in a Patient Who Has Already Received a Loading Dose (LD) of Clopidogrel Unknown status NCT01365221 Phase 4
27 "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- Unknown status NCT02028234 Phase 4
28 LDL-C Lowering Efficacy and Safety of Rosuvastatin 20 mg/Day to10 mg/Day in Chinese ACS(Acute Coronary Syndrome) Patients Unknown status NCT02077257 Phase 4
29 Potential Impact of Cigarette Smoking on Platelet Reactivity in Patients on Dual Antiplatelet Therapy With P2Y12 Inhibitors Unknown status NCT02026713 Phase 4
30 Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention Unknown status NCT01968577 Phase 4
31 Regression of Fatty Heart by Valsartan Therapy Unknown status NCT00745953 Phase 4
32 Effects of Iloprost Treatment in Adult Patients With Pulmonary Arterial Hypertension Related to Congenital Heart Disease Unknown status NCT01383083 Phase 4
33 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Unknown status NCT01823770 Phase 4
34 The Effects of Continuous Positive Airway Pressure on Overlap Syndrome Unknown status NCT00914264 Phase 4
35 Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit Unknown status NCT02025855 Phase 4
36 Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study Completed NCT02612116 Phase 4
37 Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome. Completed NCT00276432 Phase 4
38 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Completed NCT00627744 Phase 4
39 Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome Completed NCT01895751 Phase 4
40 Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) Completed NCT00790907 Phase 4
41 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4
42 Abciximab, Clopidogrel and Percutaneous Coronary Intervention in Acute Coronary Syndrome (ISAR-REACT-2) Completed NCT00133003 Phase 4
43 The Effect of Pioglitazone on Neointima Volume and Characteristics Observed by Optical Coherence Tomography (OCT) Completed NCT01331967 Phase 4
44 CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events Completed NCT00327418 Phase 4
45 Aspirin Non-responsiveness and Clopidogrel Endpoint Trial. Completed NCT00222261 Phase 4
46 Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease Completed NCT00181818 Phase 4
47 A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies Completed NCT00566774 Phase 4
48 DANish Multicenter STENT Trial Completed NCT00139802 Phase 4
49 Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease Completed NCT01637012 Phase 4
50 Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study Completed NCT00905671 Phase 4

Search NIH Clinical Center for Intermediate Coronary Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: angina, unstable

Genetic Tests for Intermediate Coronary Syndrome

Anatomical Context for Intermediate Coronary Syndrome

MalaCards organs/tissues related to Intermediate Coronary Syndrome:

39
Trachea, Lung

Publications for Intermediate Coronary Syndrome

Articles related to Intermediate Coronary Syndrome:

(show all 22)
id Title Authors Year
1
Management of intermediate coronary syndrome: role of conservative treatment, glycoprotein IIb/IIIa receptor inhibitors, and direct intervention. ( 11076127 )
2000
2
A prospective study of an algorithm using cardiac troponin I and myoglobin as adjuncts in the diagnosis of acute myocardial infarction and intermediate coronary syndromes in a veteran's hospital. ( 11129678 )
2000
3
Unstable angina pectoris. Platelet behavior and prognosis in progressive angina and intermediate coronary syndrome. ( 2136815 )
1990
4
Atenolol, heparin and the intermediate coronary syndrome. ( 6113419 )
1981
5
The intermediate coronary syndrome. ( 6971456 )
1981
6
Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. ( 6112564 )
1981
7
Pathophysiologic significance of S-T and T wave abnormalities in patients with the intermediate coronary syndrome. ( 299974 )
1977
8
Long-term follow-up in patients receiving emergency revascularization for intermediate coronary syndrome. ( 4600203 )
1974
9
SURGICAL MANAGEMENT OF THE INTERMEDIATE CORONARY SYNDROME. ( 15215960 )
1974
10
Editorial: Intermediate coronary syndrome. ( 4148257 )
1973
11
The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. ( 4144755 )
1973
12
The natural history of intermediate coronary syndrome. ( 4721961 )
1973
13
Letter: Intermediate coronary syndrome. ( 4752330 )
1973
14
Bradycardia in intermediate coronary syndrome. ( 4723578 )
1973
15
Early diagnosis of acute myocardial infarction with special reference to the diagnosis of the intermediate coronary syndrome. A clinical study. ( 4586014 )
1972
16
Recognition and management of the intermediate coronary syndrome. ( 6021604 )
1967
17
Diagnosis and management of the intermediate coronary syndrome. A clinical study of 400 cases of the syndrome. ( 5932254 )
1966
18
THE INTERMEDIATE CORONARY SYNDROME. ( 14061336 )
1963
19
Intermediate coronary syndrome. ( 13779654 )
1961
20
Electrocardiographic changes in the intermediate coronary syndrome. II. Location of lesions. ( 13286446 )
1956
21
The intermediate coronary syndrome. ( 13226558 )
1955
22
I. Electrocardiographic changes in the intermediate coronary syndrome. ( 13211952 )
1954

Variations for Intermediate Coronary Syndrome

Expression for Intermediate Coronary Syndrome

Search GEO for disease gene expression data for Intermediate Coronary Syndrome.

Pathways for Intermediate Coronary Syndrome

GO Terms for Intermediate Coronary Syndrome

Cellular components related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.87 ACE CRP F3 IL6 PLAT SELP
2 platelet alpha granule membrane GO:0031092 9.37 ITGA2B SELP
3 external side of plasma membrane GO:0009897 9.35 ACE IL6 ITGA2B P2RY12 SELP
4 cardiac myofibril GO:0097512 9.26 TNNI3 TNNT2
5 cardiac Troponin complex GO:1990584 9.16 TNNI3 TNNT2
6 troponin complex GO:0005861 8.8 TNNI3 TNNT1 TNNT2

Biological processes related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.69 ITGA2B SELP VWF
2 platelet activation GO:0030168 9.67 IL6 P2RY12 VWF
3 skeletal muscle contraction GO:0003009 9.52 TNNI3 TNNT1
4 muscle filament sliding GO:0030049 9.5 TNNI3 TNNT1 TNNT2
5 heart contraction GO:0060047 9.48 ACE TNNI3
6 positive regulation of leukocyte migration GO:0002687 9.46 ITGA2B SELP
7 neutrophil mediated immunity GO:0002446 9.43 ACE IL6
8 negative regulation of lipid storage GO:0010888 9.4 CRP IL6
9 negative regulation of ATPase activity GO:0032780 9.37 TNNI3 TNNT2
10 blood coagulation GO:0007596 9.35 F3 P2RY12 PLAT SERPINC1 VWF
11 regulation of muscle contraction GO:0006937 9.33 TNNI3 TNNT1 TNNT2
12 slow-twitch skeletal muscle fiber contraction GO:0031444 9.26 MB TNNT1
13 hemostasis GO:0007599 8.92 F3 P2RY12 SERPINC1 VWF

Molecular functions related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.43 F3 SERPINC1 VWF
2 glycoprotein binding GO:0001948 9.33 PLAT SELP VWF
3 tropomyosin binding GO:0005523 9.32 TNNT1 TNNT2
4 troponin T binding GO:0031014 8.96 TNNI3 TNNT1
5 troponin C binding GO:0030172 8.62 TNNI3 TNNT2

Sources for Intermediate Coronary Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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