MCID: INT007
MIFTS: 55

Intermediate Coronary Syndrome

Categories: Cardiovascular diseases, Cancer diseases

Aliases & Classifications for Intermediate Coronary Syndrome

MalaCards integrated aliases for Intermediate Coronary Syndrome:

Name: Intermediate Coronary Syndrome 12 14
Angina, Unstable 41 69
Myocardial Preinfarction Syndrome 69
Carcinoma in Situ of Trachea 69
Tracheal Carcinoma in Situ 12
Anginal Chest Pain at Rest 12
Impending Infarction 12
Preinfarction Angina 12
Worsening Angina 12
Unstable Angina 12
Angina at Rest 12

Classifications:



Summaries for Intermediate Coronary Syndrome

MalaCards based summary : Intermediate Coronary Syndrome, also known as angina, unstable, is related to angina pectoris and acute myocardial infarction, and has symptoms including hoarseness, hemoptysis and dyspnea. An important gene associated with Intermediate Coronary Syndrome is UBAP1 (Ubiquitin Associated Protein 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. The drugs Pravastatin and Aspirin have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and kidney, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Intermediate Coronary Syndrome

Diseases related to Intermediate Coronary Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 angina pectoris 28.2 ACE CRP F3 IL6 PLAT SERPINC1
2 acute myocardial infarction 26.4 ACE CRP F3 ITGA2B MB PIK3C2A
3 myocardial infarction 24.7 ACE CRP F3 IL6 ITGA2B MB
4 prinzmetal's variant angina 11.5
5 coronary heart disease 1 11.5
6 trachea carcinoma in situ 11.2
7 familial isolated restrictive cardiomyopathy 10.6 TNNI3 TNNT2
8 intracranial sinus thrombosis 10.4 F3 SERPINC1
9 fournier gangrene 10.4 F3 SERPINC1
10 renal artery obstruction 10.4 ACE SERPINC1
11 sagittal sinus thrombosis 10.3 F3 SERPINC1
12 fibrinolytic defect 10.3 PLAT SERPINC1
13 restrictive cardiomyopathy 10.3 TNNI3 TNNT1 TNNT2
14 granulomatous hepatitis 10.3 ACE CRP ITGA2B
15 conjugate gaze palsy 10.3 F3 PLG
16 myocardial stunning 10.3 SERPINC1 TNNI3 TNNT2
17 inherited blood coagulation disease 10.3 F3 ITGA2B SERPINC1
18 qualitative platelet defect 10.3 F3 SELP
19 peripheral vertigo 10.3 CRP F3 SERPINC1
20 tick paralysis 10.3 PIK3C2A TNNI3
21 cerebral falx meningioma 10.3 F3 PLG
22 aortic valve disease 1 10.3 ACE CRP TNNI3
23 thrombocytopenia due to platelet alloimmunization 10.3 ITGA2B SELP
24 japanese spotted fever 10.3 CRP SERPINC1
25 intrinsic cardiomyopathy 10.3 ACE TNNI3 TNNT2
26 aortic valve disease 2 10.3 ACE CRP TNNI3
27 anterolateral myocardial infarction 10.3 ACE PLAT
28 argentine hemorrhagic fever 10.3 PLAT SERPINC1
29 thrombasthenia 10.3 F3 ITGA2B SELP
30 atrial standstill 1 10.3 ACE TNNI3 TNNT2
31 ischemic colitis 10.3 ACE SERPINC1
32 glanzmann thrombasthenia 10.2 F3 ITGA2B SELP
33 generalized atherosclerosis 10.2 ACE CRP SELP
34 coronary restenosis 10.2 ACE SERPINC1
35 alpha-2-plasmin inhibitor deficiency 10.2 PLG SERPINC1
36 virus associated hemophagocytic syndrome 10.2 MB PIK3C2A
37 heparin-induced thrombocytopenia 10.2 F3 SELP SERPINC1
38 lemierre's syndrome 10.2 CRP F3 PLG
39 carotid stenosis 10.2 ACE CRP SELP
40 interstitial myocarditis 10.2 MB PIK3C2A
41 ligneous conjunctivitis 10.2 PLAT PLG
42 marantic endocarditis 10.2 F3 PLAT SERPINC1
43 purpura 10.1 CRP F3 ITGA2B SERPINC1
44 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.1 MB PIK3C2A
45 systemic scleroderma 10.1 ACE CRP SELP
46 creatine phosphokinase, elevated serum 10.1 MB PIK3C2A
47 venous insufficiency 10.1 CRP PLAT SELP
48 cold agglutinin disease 10.1 CRP IL6
49 thrombophilia due to thrombin defect 10.1 F3 PLAT SERPINC1
50 gas gangrene 10.1 PIK3C2A TNNI3 TNNT2

Comorbidity relations with Intermediate Coronary Syndrome via Phenotypic Disease Network (PDN): (show top 50) (show all 104)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Kidney Failure
Acute Myocardial Infarction Acute Stress Disorder
Allergic Urticaria Anthracosis
Anxiety Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 1
Aortic Valve Disease 2 Asbestosis
Atrioventricular Block Atrophic Gastritis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Bleeding Disorder, Platelet-Type, 11
Bronchitis Cardiac Arrest
Cardiac Arrhythmia Cardiogenic Shock
Cerebrovascular Disease Chronic Intestinal Vascular Insufficiency
Chronic Kidney Failure Chronic Myocardial Ischemia
Constrictive Pericarditis Coronary Artery Aneurysm
Deficiency Anemia Diabetic Polyneuropathy
Diaphragm Disease Dressler's Syndrome
Duodenitis Dyskinesia of Esophagus
Dysthymic Disorder Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Gallbladder Disease Gastroesophageal Reflux
Generalized Atherosclerosis Gout
Heart Disease Hemopericardium
Hyperlipoproteinemia, Type I Hyperlipoproteinemia, Type Iv
Hyperlipoproteinemia, Type V Hypertension, Essential

Graphical network of the top 20 diseases related to Intermediate Coronary Syndrome:



Diseases related to Intermediate Coronary Syndrome

Symptoms & Phenotypes for Intermediate Coronary Syndrome

UMLS symptoms related to Intermediate Coronary Syndrome:


hoarseness, hemoptysis, dyspnea, coughing, angina pectoris

MGI Mouse Phenotypes related to Intermediate Coronary Syndrome:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.22 CRP PIK3C2A F3 PLAT IL6 PLG
2 homeostasis/metabolism MP:0005376 10.13 CRP PIK3C2A F3 PLAT IL6 PLG
3 hematopoietic system MP:0005397 10.11 PIK3C2A F3 PLAT IL6 PLG ITGA2B
4 immune system MP:0005387 9.96 CRP PIK3C2A F3 PLAT IL6 PLG
5 mortality/aging MP:0010768 9.9 PIK3C2A F3 PLAT IL6 PLG MB
6 muscle MP:0005369 9.5 F3 PLAT IL6 MB TNNI3 TNNT1
7 respiratory system MP:0005388 9.17 F3 PLAT IL6 PLG MB SELP

Drugs & Therapeutics for Intermediate Coronary Syndrome

Drugs for Intermediate Coronary Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 341)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
2
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
3
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2 33069-62-4 36314
4
Colchicine Approved Phase 4,Phase 3 64-86-8 2833 6167
5
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1 120202-66-6, 113665-84-2 60606
6
Etanercept Approved, Investigational Phase 4 185243-69-0
7
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
9
Citalopram Approved Phase 4 59729-33-8 2771
10
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
11
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
12
Hydroxocobalamin Approved Phase 4,Phase 3 13422-51-0 5460373 44475014 11953898
13
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
14
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
15
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 46835353 6436030 5284616
16
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
17
Dopamine Approved Phase 4,Phase 3 51-61-6, 62-31-7 681
18
Nitric Oxide Approved Phase 4 10102-43-9 145068
19
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
20
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
21
Simvastatin Approved Phase 4,Phase 2,Phase 3 79902-63-9 54454
22
Fluvastatin Approved Phase 4,Phase 3 93957-54-1 1548972
23
Glipizide Approved, Investigational Phase 4 29094-61-9 3478
24
Metformin Approved Phase 4 657-24-9 4091 14219
25
Ramipril Approved Phase 4 87333-19-5 5362129
26
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
27
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
28
Amlodipine Approved Phase 4 88150-42-9 2162
29
Bisoprolol Approved Phase 4 66722-44-9 2405
30
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
31
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
32
Bupropion Approved Phase 4,Phase 3 34911-55-2, 34841-39-9 444
33
Adenosine Approved, Investigational Phase 4 58-61-7 60961
34
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
35
Piroxicam Approved, Investigational Phase 4 36322-90-4 54676228 5280452
36
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
37
Chromium Approved Phase 4,Phase 2,Phase 3 7440-47-3 27668
38
Lornoxicam Approved, Investigational Phase 4 70374-39-9 5282204
39
Saxagliptin Approved Phase 4 361442-04-8 11243969
40 Fondaparinux Approved, Investigational Phase 4,Phase 3 104993-28-4
41
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
42
Dalteparin Approved Phase 4,Phase 3 9005-49-6
43
Morphine Approved, Investigational Phase 4 57-27-2 5288826
44
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3 58-93-5 3639
45
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
46
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
47
Cangrelor Approved Phase 4 163706-06-7 9854012
48
Lesinurad Approved, Investigational Phase 4 878672-00-5 53465279
49
Fenofibrate Approved Phase 4,Phase 3 49562-28-9 3339
50
Bezafibrate Approved, Investigational Phase 4 41859-67-0 39042

Interventional clinical trials:

(show top 50) (show all 427)

# Name Status NCT ID Phase Drugs
1 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
2 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
3 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
4 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
5 Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population Unknown status NCT01556126 Phase 4
6 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
7 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
8 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
9 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4 Udenafil;placebo
10 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
11 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
12 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
13 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
14 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
15 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
16 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
17 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
18 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
19 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
20 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4 Levothyroxine supplementation
21 Danhong Injection in the Treatment of Unstable Angina Pectoris Completed NCT02007187 Phase 4 Danhong injection;Placebo
22 Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study Completed NCT02612116 Phase 4 Pulverized ticagrelor sublingually;Pulverized ticagrelor orally;Integral ticagrelor
23 Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome. Completed NCT00276432 Phase 4
24 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Completed NCT00627744 Phase 4 Sitagliptin
25 Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) Completed NCT00790907 Phase 4 fondaparinux background and standard dose UFH;Fondaparinux background and low dose heparin;Open label fondaparinux
26 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4 Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
27 Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome Completed NCT01895751 Phase 4
28 Aspirin Non-responsiveness and Clopidogrel Endpoint Trial. Completed NCT00222261 Phase 4 aspirin;clopidogrel
29 The Effect of Pioglitazone on Neointima Volume and Characteristics Observed by Optical Coherence Tomography (OCT) Completed NCT01331967 Phase 4 Pioglitazone
30 A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies Completed NCT00566774 Phase 4
31 Efficacy and Safety of Lornoxicam in Patients With Acute Coronary Syndrome Completed NCT00997750 Phase 4 Lornoxicam
32 Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease Completed NCT00181818 Phase 4 bupropion SR (sustained-release)
33 Multiple Interventions Related to Dialysis Procedures in Order to Reduce Cardiovascular Morbidity and Mortality in HD Patients(EGESTUDY) Completed NCT00295191 Phase 4
34 Resistance to Aspirin and/or Clopidogrel Among Patients With PAD. Completed NCT00262561 Phase 4 Aspirin
35 Comparison of Post-dilution On-line Hemodiafiltration and Hemodialysis Completed NCT00411177 Phase 4
36 Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease Completed NCT01637012 Phase 4
37 Acarbose Cardiovascular Evaluation Trial Completed NCT00829660 Phase 4 Acarbose;Matching Placebo
38 The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) Completed NCT01341730 Phase 4 Atorvastatin 20mg;Atorvastatin 20 mg + Pioglitazone 30 mg
39 DANish Multicenter STENT Trial Completed NCT00139802 Phase 4
40 Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI Completed NCT01293097 Phase 4 Atorvastatin;Statin
41 Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression Completed NCT01212900 Phase 4 Statin Drugs
42 Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease Completed NCT03011775 Phase 4 Pioglitazone 15 mg Tablet;Isosorbide Dinitrate 10Mg Tablet;Acetylsalicylic Acid 75Mg Tablet;Bisoprolol Fumarate 2.5 MG Oral Tablet;Rosuvastatin Calcium 20 MG Oral Tablet;ramipril 5 MG
43 Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications Completed NCT01107886 Phase 4 Saxagliptin;Placebo
44 Randomized Trial of Immediate Versus Early and Selective Invasive Percutaneous Coronary Intervention in NSTEMI Completed NCT00402675 Phase 4
45 Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke Completed NCT00147602 Phase 4 atorvastatin
46 The Use of Cilostazol in Patients With Diabetic Nephropathy Completed NCT00272831 Phase 4 Cilostazol;Placebo
47 CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events Completed NCT00327418 Phase 4 Atorvastatin
48 The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente Completed NCT01066650 Phase 4
49 Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease Completed NCT00513630 Phase 4 Glipizide;Metformin
50 Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent Completed NCT01826552 Phase 4

Search NIH Clinical Center for Intermediate Coronary Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: angina, unstable

Genetic Tests for Intermediate Coronary Syndrome

Anatomical Context for Intermediate Coronary Syndrome

MalaCards organs/tissues related to Intermediate Coronary Syndrome:

38
Heart, Testes, Kidney, Trachea, Lung, Liver, Endothelial

Publications for Intermediate Coronary Syndrome

Articles related to Intermediate Coronary Syndrome:

(show all 22)
# Title Authors Year
1
Management of intermediate coronary syndrome: role of conservative treatment, glycoprotein IIb/IIIa receptor inhibitors, and direct intervention. ( 11076127 )
2000
2
A prospective study of an algorithm using cardiac troponin I and myoglobin as adjuncts in the diagnosis of acute myocardial infarction and intermediate coronary syndromes in a veteran's hospital. ( 11129678 )
2000
3
Unstable angina pectoris. Platelet behavior and prognosis in progressive angina and intermediate coronary syndrome. ( 2136815 )
1990
4
Atenolol, heparin and the intermediate coronary syndrome. ( 6113419 )
1981
5
Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. ( 6112564 )
1981
6
The intermediate coronary syndrome. ( 6971456 )
1981
7
Pathophysiologic significance of S-T and T wave abnormalities in patients with the intermediate coronary syndrome. ( 299974 )
1977
8
SURGICAL MANAGEMENT OF THE INTERMEDIATE CORONARY SYNDROME. ( 15215960 )
1974
9
Long-term follow-up in patients receiving emergency revascularization for intermediate coronary syndrome. ( 4600203 )
1974
10
Bradycardia in intermediate coronary syndrome. ( 4723578 )
1973
11
Letter: Intermediate coronary syndrome. ( 4752330 )
1973
12
The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. ( 4144755 )
1973
13
Editorial: Intermediate coronary syndrome. ( 4148257 )
1973
14
The natural history of intermediate coronary syndrome. ( 4721961 )
1973
15
Early diagnosis of acute myocardial infarction with special reference to the diagnosis of the intermediate coronary syndrome. A clinical study. ( 4586014 )
1972
16
Recognition and management of the intermediate coronary syndrome. ( 6021604 )
1967
17
Diagnosis and management of the intermediate coronary syndrome. A clinical study of 400 cases of the syndrome. ( 5932254 )
1966
18
THE INTERMEDIATE CORONARY SYNDROME. ( 14061336 )
1963
19
Intermediate coronary syndrome. ( 13779654 )
1961
20
Electrocardiographic changes in the intermediate coronary syndrome. II. Location of lesions. ( 13286446 )
1956
21
The intermediate coronary syndrome. ( 13226558 )
1955
22
I. Electrocardiographic changes in the intermediate coronary syndrome. ( 13211952 )
1954

Variations for Intermediate Coronary Syndrome

Expression for Intermediate Coronary Syndrome

Search GEO for disease gene expression data for Intermediate Coronary Syndrome.

Pathways for Intermediate Coronary Syndrome

Pathways related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.99 F3 ITGA2B P2RY12 PLAT PLG SELP
2
Show member pathways
12.04 CRP IL6 PLAT PLG
3
Show member pathways
11.82 F3 PLAT PLG SERPINC1
4 11.81 IL6 TNNI3 TNNT2
5 11.7 F3 PLAT PLG SERPINC1
6 11.62 IL6 TNNI3 TNNT2
7
Show member pathways
11.59 ACE IL6 ITGA2B TNNI3 TNNT2
8 11.47 TNNI3 TNNT1 TNNT2
9 10.77 CRP IL6
10 10.69 ACE PLAT PLG
11 10.61 IL6 PLAT PLG SELP
12 10.59 PLAT PLG

GO Terms for Intermediate Coronary Syndrome

Cellular components related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.8 F3 ITGA2B P2RY12 PLAT PLG
2 extracellular space GO:0005615 9.76 ACE CRP F3 IL6 PLAT PLG
3 external side of plasma membrane GO:0009897 9.62 ACE ITGA2B P2RY12 SELP
4 platelet alpha granule membrane GO:0031092 9.43 ITGA2B SELP
5 cardiac myofibril GO:0097512 9.26 TNNI3 TNNT2
6 cardiac Troponin complex GO:1990584 8.96 TNNI3 TNNT2
7 troponin complex GO:0005861 8.8 TNNI3 TNNT1 TNNT2
8 extracellular exosome GO:0070062 10.02 ACE CRP F3 ITGA2B MB PIK3C2A

Biological processes related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.67 ITGA2B PLG SELP
2 fibrinolysis GO:0042730 9.51 PLAT PLG
3 muscle filament sliding GO:0030049 9.5 TNNI3 TNNT1 TNNT2
4 heart contraction GO:0060047 9.48 ACE TNNI3
5 positive regulation of leukocyte migration GO:0002687 9.46 ITGA2B SELP
6 neutrophil mediated immunity GO:0002446 9.43 ACE IL6
7 negative regulation of ATPase activity GO:0032780 9.4 TNNI3 TNNT2
8 negative regulation of lipid storage GO:0010888 9.37 CRP IL6
9 blood coagulation GO:0007596 9.35 F3 P2RY12 PLAT PLG SERPINC1
10 regulation of muscle contraction GO:0006937 9.33 TNNI3 TNNT1 TNNT2
11 slow-twitch skeletal muscle fiber contraction GO:0031444 9.26 MB TNNT1
12 hemostasis GO:0007599 8.92 F3 P2RY12 PLG SERPINC1

Molecular functions related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tropomyosin binding GO:0005523 9.16 TNNT1 TNNT2
2 troponin T binding GO:0031014 8.96 TNNI3 TNNT1
3 troponin C binding GO:0030172 8.62 TNNI3 TNNT2

Sources for Intermediate Coronary Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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