MCID: INT007
MIFTS: 55

Intermediate Coronary Syndrome malady

Cardiovascular diseases category

Summaries for Intermediate Coronary Syndrome

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MalaCards based summary: Intermediate Coronary Syndrome, also known as anginal chest pain at rest, is related to ischemia and coronary artery disease. An important gene associated with Intermediate Coronary Syndrome is AMH (anti-Mullerian hormone), and among its related pathways are Striated Muscle Contraction and Cardiac Progenitor Differentiation. The drugs heparin and heparin sodium and the compounds microplasmin and reviparin have been mentioned in the context of this disorder. Affiliated tissues include lung, and related mouse phenotypes are reproductive system and cardiovascular system.

Aliases & Classifications for Intermediate Coronary Syndrome

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Sources:
10Disease Ontology, 12DISEASES, 62UMLS, 45Novoseek, 40NCIt, 35MeSH, 57SNOMED-CT, 29ICD9CM, 27ICD10
See all sources

Intermediate Coronary Syndrome, Aliases & Descriptions:

Name: Intermediate Coronary Syndrome 10 12 62
Anginal Chest Pain at Rest 10 62
Impending Infarction 10 62
Angina at Rest 10 62
Myocardial Preinfarction Syndrome 62
Preinfarction Syndrome 10
Angina, Preinfarction 62
Preinfarction Angina 10
 
Angina: Crescendo 10
Crescendo Angina 45
Angina, Unstable 62
Worsening Angina 10
Unstable Angina 10
Unstable 10
at Rest 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Related Diseases for Intermediate Coronary Syndrome

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Diseases related to Intermediate Coronary Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1ischemia31.0PIK3C2A, TNNT2, PF4, PLAT, PLG, MB
2coronary artery disease30.8PIK3C2A, PF4, ITGA2B, PLAT, PLG, MB
3coronary thrombosis30.8PLAT, SERPINC1
4atherosclerosis30.5SERPINC1, PF4, ITGA2B, PLAT, PLG, MB
5congestive heart failure30.3TNNT2, TNNI3
6thrombocytosis30.2SERPINC1, PF4
7antiphospholipid syndrome30.2PLAT, PF4, SERPINC1
8myocardial infarction30.1SERPINC1, AMH, PF4, ITGA2B, PLAT, PLG
9vascular disease30.1PIK3C2A, TNNT2, TNNI3, SERPINC1, PF4, MB
10atrial fibrillation30.0PLAT, PF4
11respiratory failure29.9SERPINC1, PIK3C2A
12acute myocardial infarction29.9PIK3C2A, TNNT2, TNNI3, SERPINC1, PF4, ITGA2B
13dilated cardiomyopathy29.9PIK3C2A, TNNT2, TNNI3, MB
14myopathy29.9MB, TNNI3, TNNT2, PIK3C2A
15endotheliitis10.6
16artery disease10.6
17coronary stenosis10.5
18blindness10.5
19cor pulmonale10.4
20myocardial stunning10.4
21pneumonia10.4
22prinzmetal's variant angina10.4
23spontaneous coronary artery dissection10.4
24subendocardial myocardial infarction10.3
25subclavian steal syndrome10.3
26essential thrombocythemia10.3
27intermittent claudication10.3
28schizophrenia10.2
29cerebritis10.2
30peripheral vascular disease10.2
31ischemic heart disease10.2
32renovascular hypertension10.2
33rheumatic fever10.2
34pituitary apoplexy10.2
35bronchiectasis10.2
36systolic heart failure10.2
37carotid stenosis10.2
38carcinoid syndrome10.2
39cytomegalovirus infection10.2
40hypoxia10.2
41coronary arterial fistulas10.2
42cystic fibrosis10.1
43pulmonary hypertension10.1
44paranoid schizophrenia10.1
45arteriosclerosis obliterans10.1
46chronic fatigue syndrome10.1
47arteriosclerosis10.1
48mitral valve disease10.1
49transposition of the great arteries10.1
50angina pectoris10.1

Graphical network of the top 20 diseases related to Intermediate Coronary Syndrome:



Diseases related to intermediate coronary syndrome

Symptoms for Intermediate Coronary Syndrome

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Drugs & Therapeutics for Intermediate Coronary Syndrome

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Genetic Tests for Intermediate Coronary Syndrome

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Anatomical Context for Intermediate Coronary Syndrome

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MalaCards organs/tissues related to Intermediate Coronary Syndrome:

33
Lung

Animal Models for Intermediate Coronary Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Intermediate Coronary Syndrome:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.5PLG, PLAT, ITGA2B, AMH, SERPINC1
2MP:00053857.7TNNT2, TNNI3, SERPINC1, ITGA2B, PLAT, PLG
3MP:00053977.1PIK3C2A, SERPINC1, PF4, ITGA2B, PLAT, PLG
4MP:00053766.7MB, PIK3C2A, TNNT2, SERPINC1, AMH, PF4
5MP:00107686.4PIK3C2A, TNNT2, TNNI3, SERPINC1, PLAT, PLG

Publications for Intermediate Coronary Syndrome

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Articles related to Intermediate Coronary Syndrome:

(show all 21)
idTitleAuthorsYear
1
Management of intermediate coronary syndrome: role of conservative treatment, glycoprotein IIb/IIIa receptor inhibitors, and direct intervention. (11076127)
2000
2
Unstable angina pectoris. Platelet behavior and prognosis in progressive angina and intermediate coronary syndrome. (2136815)
1990
3
Atenolol, heparin and the intermediate coronary syndrome. (6113419)
1981
4
Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. (6112564)
1981
5
The intermediate coronary syndrome. (6971456)
1981
6
Pathophysiologic significance of S-T and T wave abnormalities in patients with the intermediate coronary syndrome. (299974)
1977
7
Long-term follow-up in patients receiving emergency revascularization for intermediate coronary syndrome. (4600203)
1974
8
SURGICAL MANAGEMENT OF THE INTERMEDIATE CORONARY SYNDROME. (15215960)
1974
9
Editorial: Intermediate coronary syndrome. (4148257)
1973
10
Bradycardia in intermediate coronary syndrome. (4723578)
1973
11
The natural history of intermediate coronary syndrome. (4721961)
1973
12
The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. (4144755)
1973
13
Letter: Intermediate coronary syndrome. (4752330)
1973
14
Early diagnosis of acute myocardial infarction with special reference to the diagnosis of the intermediate coronary syndrome. A clinical study. (4586014)
1972
15
Recognition and management of the intermediate coronary syndrome. (6021604)
1967
16
Diagnosis and management of the intermediate coronary syndrome. A clinical study of 400 cases of the syndrome. (5932254)
1966
17
THE INTERMEDIATE CORONARY SYNDROME. (14061336)
1963
18
Intermediate coronary syndrome. (13779654)
1961
19
Electrocardiographic changes in the intermediate coronary syndrome. II. Location of lesions. (13286446)
1956
20
The intermediate coronary syndrome. (13226558)
1955
21
I. Electrocardiographic changes in the intermediate coronary syndrome. (13211952)
1954

Variations for Intermediate Coronary Syndrome

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Expression for genes affiliated with Intermediate Coronary Syndrome

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Search GEO for disease gene expression data for Intermediate Coronary Syndrome.

Pathways for genes affiliated with Intermediate Coronary Syndrome

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Compounds for genes affiliated with Intermediate Coronary Syndrome

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Compounds related to Intermediate Coronary Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 98)
idCompoundScoreTop Affiliating Genes
1microplasmin459.9PLAT, PLG
2reviparin459.9SERPINC1, PLAT
3integrilin459.9SERPINC1, PLAT
4alpha-hydroxybutyrate459.9MB, PIK3C2A
5efegatran459.9SERPINC1, PLAT
6spectrozyme459.8PLAT, SERPINC1
7eaca459.7SERPINC1, PLAT
8polybrene459.7PF4, SERPINC1
9p-amino benzamidine459.6SERPINC1, PLAT
10danaparoid459.6SERPINC1, PF4
11ancrod459.6SERPINC1, PLAT
12tranexamic acid45 1310.5SERPINC1, PLAT, PLG
13epsilon aminocaproic acid459.5SERPINC1, PLAT, PLG
14isopropanol459.5MB, PF4
15fluvastatin45 51 30 1312.4MB, PLAT, PIK3C2A
16fibrinopeptide a459.3PLAT, PF4, SERPINC1
17fondaparinux459.3SERPINC1, PF4, PLAT
18protamine sulfate459.3SERPINC1, PF4, PLAT
19ticlopidine45 1310.3PLAT, PF4, SERPINC1
20iloprost61 30 45 1312.3PLAT, PF4, SERPINC1
21protamine459.3PLAT, PF4, SERPINC1
22dermatan sulfate459.2SERPINC1, PF4, PLAT
23tamoxifen45 51 30 1312.2PLG, PLAT, AMH, SERPINC1
24polyethylene glycol459.2MB, PF4, SERPINC1
25thromboxane45 2610.2PIK3C2A, PF4, PLAT
26pge1459.1PLAT, PF4, PIK3C2A
27thromboxane a245 2610.1PIK3C2A, PF4, PLAT
28tirofiban45 1310.0PLAT, ITGA2B, PF4, SERPINC1
29abciximab45 1310.0SERPINC1, PF4, ITGA2B, PLAT
30homocysteine45 2610.0PLAT, SERPINC1, PIK3C2A
31ascorbic acid45 269.9PIK3C2A, SERPINC1, PLAT, MB
32kininogen458.9PLG, PLAT, PF4, SERPINC1
33ptca458.9PLAT, PF4, TNNT2, PIK3C2A
34citrate458.9PIK3C2A, SERPINC1, PF4, MB
35nicotine45 30 51 1311.9SERPINC1, PF4, PLAT, MB
36hirudin458.8PIK3C2A, SERPINC1, PF4, PLAT
37warfarin45 51 26 1311.8PIK3C2A, SERPINC1, PF4, PLAT
38prostacyclin458.8PIK3C2A, SERPINC1, PF4, PLAT
39sodium nitroprusside458.7MB, PLAT, PIK3C2A
40estradiol45 26 1310.7PIK3C2A, AMH, PF4, PLAT
41lactate458.7MB, PF4, TNNI3, TNNT2, PIK3C2A
42lysine458.5PF4, ITGA2B, PLAT, PLG
43aprotinin45 139.5SERPINC1, PF4, PLAT, PLG, MB
44alanine458.4PIK3C2A, TNNT2, SERPINC1, PF4, MB
45vegf458.4PIK3C2A, SERPINC1, PF4, PLG, MB
46adp45 30 2610.3PIK3C2A, SERPINC1, PF4, ITGA2B, PLAT
47cysteine458.2PF4, ITGA2B, PLAT, PLG, MB
48fibrinogen458.1PIK3C2A, SERPINC1, PF4, ITGA2B, PLAT, PLG
49creatinine457.7MB, PIK3C2A, TNNT2, TNNI3, SERPINC1, PF4
50heparin45 30 26 1310.7PIK3C2A, TNNT2, SERPINC1, PF4, PLAT, PLG

GO Terms for genes affiliated with Intermediate Coronary Syndrome

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Cellular components related to Intermediate Coronary Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1troponin complexGO:00058619.9TNNI3, TNNT2
2sarcomereGO:00300179.5TNNI3, TNNT2
3platelet alpha granule lumenGO:00310939.5PLG, PF4
4blood microparticleGO:00725629.3SERPINC1, ITGA2B, PLG
5extracellular spaceGO:00056158.3PLG, PLAT, PF4, AMH, SERPINC1
6extracellular regionGO:00055768.1SERPINC1, AMH, PF4, PLAT, PLG

Biological processes related to Intermediate Coronary Syndrome according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of ATPase activityGO:00327809.9TNNT2, TNNI3
2muscle filament slidingGO:00300499.8TNNI3, TNNT2
3ventricular cardiac muscle tissue morphogenesisGO:00550109.7TNNT2, TNNI3
4fibrinolysisGO:00427309.6PLAT, PLG
5platelet degranulationGO:00025769.3PF4, ITGA2B, PLG
6platelet activationGO:00301689.2PLG, ITGA2B, PF4
7platelet-derived growth factor receptor signaling pathwayGO:00480089.1PIK3C2A, PLAT
8blood coagulationGO:00075968.4PLG, PLAT, ITGA2B, PF4, SERPINC1

Molecular functions related to Intermediate Coronary Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1troponin C bindingGO:00301729.8TNNI3, TNNT2

Products for genes affiliated with Intermediate Coronary Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Intermediate Coronary Syndrome

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet