MCID: INT059
MIFTS: 34

Internal Hemorrhoid malady

Category: Cardiovascular diseases

Aliases & Classifications for Internal Hemorrhoid

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Aliases & Descriptions for Internal Hemorrhoid:

Name: Internal Hemorrhoid 11 13
 
Internal Hemorrhoids 66

Classifications:



External Ids:

Disease Ontology11 DOID:9749
ICD9CM30 455.6
SNOMED-CT60 82985000
ICD1028 I84.1, I84.2

Summaries for Internal Hemorrhoid

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MalaCards based summary: Internal Hemorrhoid, also known as internal hemorrhoids, is related to hemorrhoid and ganglion or cyst of synovium/tendon/bursa. An important gene associated with Internal Hemorrhoid is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are Cell adhesion_Cell-matrix glycoconjugates and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include liver, and related mouse phenotypes are vision/eye and hematopoietic system.

Related Diseases for Internal Hemorrhoid

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Diseases in the Hemorrhoid family:

internal hemorrhoid

Diseases related to Internal Hemorrhoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 122)
idRelated DiseaseScoreTop Affiliating Genes
1hemorrhoid10.8
2ganglion or cyst of synovium/tendon/bursa10.5MMP9, NOS2
3brain ischemia10.5MMP7, MMP9
4malakoplakia10.5MMP9, NOS2
5immunodeficiency 27b, mycobacteriosis, ad10.5MMP7, MMP9
6multifocal choroiditis10.5MMP7, MMP9
7rectum squamous cell carcinoma10.5CD34, MMP9
8classic endocrine tumor of appendix10.4MMP1, MMP9
9follicular mucinosis10.4MMP1, MMP9
10tibialis tendinitis10.4MMP7, MMP9
11mechanical ectropion10.4MMP1, MMP9
12congenital chloride diarrhea10.4MMP1, NOS2
13chronic interstitial cystitis10.4MMP7, MMP9
14myosin storage myopathy10.3MMP2, MMP9
15renal pelvis carcinoma10.3MMP2, MMP9
16deletion 5q3510.3MMP2, MMP9
17burn scar10.3MMP7, MMP9
18sialadenitis10.3MMP2, MMP9
19penis squamous cell carcinoma10.3MMP2, MMP9
20cecum adenoma10.3MMP2, MMP9
21cyclosporiasis10.3MMP2, MMP9
22spindle epithelial tumor with thymus-like differentiation tumor10.3MMP2, MMP9
23tubular adenocarcinoma10.3MMP2, MMP9
24volkmann contracture10.3MMP2, MMP9
25schwannomatosis10.3MMP2, MMP9
26corpus callosum dysgenesis cleft spasm10.3MMP1, MMP7
27brucella canis brucellosis10.3MMP2, MMP9
28spinal stenosis10.3MMP9, NOS2
29cavernous hemangioma of colon10.3MMP2, MMP9
30glossopharyngeal nerve neoplasm10.2MMP1, MMP9
31retinal dystrophies primarily involving bruch's membrane10.2MMP2, MMP9
32bone squamous cell carcinoma10.2MMP2, MMP9
33keratopathy10.2MMP1, MMP2
34hepatopulmonary syndrome10.2MMP1, MMP2
35fibromatosis, gingival, 110.2MMP1, MMP2
36subacute monocytic leukemia10.2MMP2, MMP9
37non-gestational choriocarcinoma10.2MMP1, MMP2
38malignant struma ovarii10.2MMP2, MMP9
39bladder urachal carcinoma10.2MMP9, VEGFA
40salt and pepper syndrome10.1MMP1, MMP2
41gallbladder lymphoma10.1MMP1, MMP2
42hemopneumothorax10.1MMP9, VEGFA
43skin amelanotic melanoma10.1MMP1, MMP2
44seminal vesicle tumor10.1MMP9, VEGFA
45marchiafava bignami disease10.1MMP9, VEGFA
46impetigo herpetiformis10.1MMP2, MMP9
47granulomatous orchitis10.1MMP1, MMP2
48chorioretinitis10.1MMP9, VEGFA
49scn8a encephalopathy10.1NOS2, VEGFA
50histidine metabolism disease10.0MMP9, VEGFA

Graphical network of the top 20 diseases related to Internal Hemorrhoid:



Diseases related to internal hemorrhoid

Symptoms for Internal Hemorrhoid

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Drugs & Therapeutics for Internal Hemorrhoid

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Drugs for Internal Hemorrhoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholinePhase 475251-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
PrilocainePhase 377721-50-64906
Synonyms:
2-(Propylamino)-O-propionotoluidide
2-(Propylamino)-o-propionotoluidide
2-Methyl-.alpha.-propylaminopropionanilide
2-Methyl-alpha-propylaminopropionanilide
721-50-6
AB00053665
AC-2100
AC1L1J7W
Ambap1786-81-8
Astra 1512
Astra 1515
BPBio1_000173
BRD-A53952395-003-05-3
BRN 2108498
BSPBio_000157
BSPBio_002604
C07531
C13H20N2O
CHEBI:8404
CHEMBL1194
CID4906
Citanest
Citanest Plain
D00553
DB00750
DivK1c_000846
EINECS 211-957-0
HSDB 3386
I01-1860
IDI1_000846
KBio1_000846
KBio2_002129
KBio2_004697
KBio2_007265
KBio3_001824
KBioGR_001883
KBioSS_002129
L 67
LS-2304
Lopac0_001005
MolPort-005-935-583
 
N-(2-Methylphenyl)-2-(propylamino)propanamide
N-(2-methylphenyl)-N(2)-propylalaninamide
N-(2-methylphenyl)-N2-propylalaninamide
N-[2-Methylphenyl]-2-[propylamino]propanamide
NCGC00015860-03
NCGC00162312-01
NINDS_000846
NSC 40027
NSC40027
O-Methyl-2-propylaminopropionanilide
O-Methyl-alpha-propylaminopropionanilide
Prestwick0_000199
Prestwick1_000199
Prestwick2_000199
Prestwick3_000199
Prilocain
Prilocaina
Prilocaina [INN-Spanish]
Prilocaine (USP/INN)
Prilocaine [USAN]
Prilocaine base
Prilocainum
Prilocainum [INN-Latin]
Prilocaïne
Propanamide, N-(2-methylphenyl)-2-(propylamino)- (9CI)
Propitocaine
Propitocaine (JAN)
S1619_Selleck
SPBio_001398
SPBio_002078
Spectrum2_001549
Spectrum3_001052
Spectrum4_001192
Spectrum5_001175
Spectrum_001649
UNII-046O35D44R
alpha-N-Propylamino-2-methylpropionanilide
alpha-n-Propylamino-2-methylpropionanilide
o-Methyl-2-propylaminopropionanilide
o-Methyl-alpha-propylaminopropionanilide
prilocaine
prilocaine base
3
LidocainePhase 31168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
4
HydrocortisonePhase 260250-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
5
butyric acidPhase 2350107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Pain Relief for Thrombosed External HaemorrhoidsCompletedNCT00717782Phase 4
2Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal HemorrhoidsCompletedNCT02130830Phase 3
3Study About Patient Comfort and Long-term Outcome After Stapled HemorrhoidopexyCompletedNCT01533363Phase 3
4Efficacy and Safety Study to Treat Subjects With Symptomatic Internal HemorrhoidsTerminatedNCT01355874Phase 3
5Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal HemorrhoidsActive, not recruitingNCT01913158Phase 2
6Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation ProbeCompletedNCT00630669
7Safety and Efficacy Study of HET Bipolar System for Treatment of Stage I and Stage II HemorrhoidsCompletedNCT01841970
8The Feasibility of Self or Partner-assisted Digital Anal Exam ScreeningCompletedNCT02384005
9Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal DiseaseRecruitingNCT02303925
10Comparison Between Single and Triple Rubber Band Ligation for the Treatment of HemorrhoidsActive, not recruitingNCT01383577
11HET Bipolar System: Validation of Outpatient Hemorrhoid TreatmentActive, not recruitingNCT02773420
12A Multi Center Clinical Trial of Rph With the Simplified Milligan-Morgan Surgery on Treatment of Mixed HemorrhoidsEnrolling by invitationNCT02306421
13The Relationship Between Haemorrhoids and Pelvic Vein RefluxNot yet recruitingNCT02039570
14Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)TerminatedNCT01199679

Search NIH Clinical Center for Internal Hemorrhoid

Genetic Tests for Internal Hemorrhoid

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Anatomical Context for Internal Hemorrhoid

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MalaCards organs/tissues related to Internal Hemorrhoid:

34
Liver

Animal Models for Internal Hemorrhoid or affiliated genes

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MGI Mouse Phenotypes related to Internal Hemorrhoid:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053917.5MMP2, MMP7, MMP9, NOS2, VEGFA
2MP:00053977.4CD34, MMP2, MMP7, MMP9, NOS2, VEGFA
3MP:00053877.0CD34, MMP1, MMP2, MMP7, MMP9, NOS2
4MP:00020066.9CD34, MMP1, MMP2, MMP7, MMP9, NOS2
5MP:00053766.7CD34, MMP1, MMP2, MMP7, MMP9, NOS2

Publications for Internal Hemorrhoid

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Articles related to Internal Hemorrhoid:

idTitleAuthorsYear
1
Rectal arterio-venous malformation (AVM) with bleeding of an internal hemorrhoid. (26879656)
2016
2
Pyogenic liver abscess as a complication of internal hemorrhoid banding. (24480193)
2014
3
Massive life-threatening lower gastrointestinal hemorrhage caused by an internal hemorrhoid in a patient receiving antiplatelet therapy: a case report. (23089912)
2012
4
Long-term outcome and efficacy of endoscopic hemorrhoid ligation for symptomatic internal hemorrhoids. (21633644)
2011
5
Stapled hemorrhoidopexy is associated with a higher long-term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. (17665254)
2007
6
Early results of the treatment of internal hemorrhoid disease by infrared coagulation and elastic banding: a prospective randomized cross-over trial. (17115317)
2006
7
Pathologic change of elastic fibers with difference of microvessel density and expression of angiogenesis-related proteins in internal hemorrhoid tissues]. (16149003)
2005
8
Internal hemorrhoid bleeding in patients with portal hypertension. (3498664)
1987
9
INTERNAL HEMORRHOID OPERATION AND AFTER CARE UNDER QUININE-UREA HYDROCHLORIDE ANESTHESIA. (18737501)
1918

Variations for Internal Hemorrhoid

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Expression for genes affiliated with Internal Hemorrhoid

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Search GEO for disease gene expression data for Internal Hemorrhoid.

Pathways for genes affiliated with Internal Hemorrhoid

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Pathways related to Internal Hemorrhoid according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
19.6MMP1, MMP9
29.5MMP1, NOS2
39.5MMP2, MMP9
49.5MMP2, MMP9
59.5MMP2, MMP9
69.5MMP2, MMP9
79.5MMP2, MMP9
89.5MMP2, MMP9
99.4MMP2, NOS2
109.3MMP1, MMP2
119.3MMP9, VEGFA
12
Show member pathways
9.3MMP9, VEGFA
139.3MMP9, VEGFA
149.2NOS2, VEGFA
159.1MMP1, VEGFA
169.1MMP1, MMP7, MMP9
17
Show member pathways
9.0MMP2, MMP7, MMP9
189.0MMP1, MMP2, MMP9
19
Show member pathways
8.7MMP2, MMP9, VEGFA
20
Show member pathways
8.7MMP2, MMP9, VEGFA
218.7MMP2, MMP9, VEGFA
228.6MMP2, MMP7, MMP9, NOS2
23
Show member pathways
8.5MMP1, MMP2, MMP7, MMP9
248.5MMP1, MMP2, MMP7, MMP9
25
Show member pathways
8.5MMP1, MMP2, MMP7, MMP9
268.1MMP1, MMP2, MMP9, VEGFA
277.7MMP1, MMP2, MMP9, NOS2, VEGFA
28
Show member pathways
7.7MMP1, MMP2, MMP7, MMP9, VEGFA
297.3MMP1, MMP2, MMP7, MMP9, NOS2, VEGFA

GO Terms for genes affiliated with Internal Hemorrhoid

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Cellular components related to Internal Hemorrhoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:00055787.8MMP1, MMP2, MMP7, MMP9, VEGFA
2extracellular regionGO:00055767.2CD34, MMP1, MMP2, MMP7, MMP9, VEGFA

Biological processes related to Internal Hemorrhoid according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1endodermal cell differentiationGO:003598710.0MMP2, MMP9
2embryo implantationGO:00075669.8MMP2, MMP9
3positive regulation of vascular smooth muscle cell proliferationGO:19047079.8MMP2, MMP9
4macrophage differentiationGO:00302259.7MMP9, VEGFA
5leukocyte migrationGO:00509009.1CD34, MMP1, MMP9
6collagen catabolic processGO:00305748.9MMP1, MMP2, MMP7, MMP9
7extracellular matrix disassemblyGO:00226178.8MMP1, MMP2, MMP7, MMP9
8response to hypoxiaGO:00016668.6MMP2, NOS2, VEGFA
9proteolysisGO:00065088.2MMP1, MMP2, MMP7, MMP9

Molecular functions related to Internal Hemorrhoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endopeptidase activityGO:00041759.7MMP1, MMP9
2metalloendopeptidase activityGO:00042228.9MMP1, MMP2, MMP7, MMP9
3serine-type endopeptidase activityGO:00042528.5MMP1, MMP2, MMP7, MMP9

Sources for Internal Hemorrhoid

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet