MCID: INT042
MIFTS: 29

Internuclear Ophthalmoplegia malady

Eye diseases category

Summaries for Internuclear Ophthalmoplegia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Internuclear ophthalmoplegia (INO) is a disorder of conjugate lateral gaze in which the affected eye... more...

MalaCards: Internuclear Ophthalmoplegia is related to myasthenia gravis and ophthalmoplegia. An important gene associated with Internuclear Ophthalmoplegia is AQP4 (aquaporin 4), and among its related pathways is Spinal Cord Injury. Affiliated tissues include eye, brain and testes.

Aliases & Classifications for Internuclear Ophthalmoplegia

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8Disease Ontology, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

internuclear ophthalmoplegia 8 60


External Ids:

Disease Ontology8 DOID:538
ICD9CM27 378.86
SNOMED-CT56 49823009
MeSH34 D015835
ICD1025 H51.2

Related Diseases for Internuclear Ophthalmoplegia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Internuclear Ophthalmoplegia:



Diseases related to internuclear ophthalmoplegia

Clinical Features for Internuclear Ophthalmoplegia

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Drugs & Therapeutics for Internuclear Ophthalmoplegia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Internuclear Ophthalmoplegia

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Anatomical Context for Internuclear Ophthalmoplegia

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32MalaCards
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MalaCards organs/tissues related to Internuclear Ophthalmoplegia:

32
Eye, Brain, Testes

Animal Models for Internuclear Ophthalmoplegia or affiliated genes

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Publications for Internuclear Ophthalmoplegia

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50PubMed
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Articles related to Internuclear Ophthalmoplegia:

(show top 50)    (show all 240)
idTitleAuthorsYear
1
Images in clinical medicine. Bilateral internuclear ophthalmoplegia in multiple sclerosis. (23323922)
2013
2
Unilateral internuclear ophthalmoplegia after minor head injury. (22461944)
2012
3
Transposition surgery for internuclear ophthalmoplegia. (22881482)
2012
4
Patterns of dissociate torsional-vertical nystagmus in internuclear ophthalmoplegia. (21951004)
2011
5
Ocular vestibular evoked myogenic potentials are abnormal in internuclear ophthalmoplegia. (21093360)
2011
6
Pseudo-internuclear ophthalmoplegia as a sign of overlapping myasthenia gravis in a patient with 'intractable' hypothyroidism. (20046005)
2010
7
Midbrain cleft as a cause of chronic internuclear ophthalmoplegia, progressive ataxia, and facial weakness. (20393349)
2010
8
Progressive supranuclear palsy with wall-eyed bilateral internuclear ophthalmoplegia syndrome. (18541806)
2008
9
Results of extraocular muscle surgery in WEBINO bilateral internuclear ophthalmoplegia patients. (18329922)
2008
10
Teaching NeuroImage: Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) from midbrain infarction. (18285530)
2008
11
Isolated bilateral internuclear ophthalmoplegia after ischemic stroke. (17548998)
2007
12
Abducens-oculomotor synkinesis associated with internuclear ophthalmoplegia and acquired abducens nerve palsy. (16915907)
2006
13
Minor head trauma and isolated unilateral internuclear ophthalmoplegia. (17044578)
2006
14
Internuclear ophthalmoplegia: causes and long-term follow-up in 65 patients. (15285772)
2004
15
Neuroanatomic evidence to explain why bilateral internuclear ophthalmoplegia may result from occlusion of a unilateral pontine branch artery. (15206438)
2004
16
Bilateral internuclear ophthalmoplegia following minor head trauma. (12554035)
2003
17
Herpes zoster vasculitis presenting as giant cell arteritis with bilateral internuclear ophthalmoplegia. (12470766)
2002
18
Partial unilateral third nerve palsy and bilateral internuclear ophthalmoplegia: an unusual presentation of multiple sclerosis. (11040928)
2000
19
Unilateral internuclear ophthalmoplegia and recovery with thiamine in Wernicke syndrome. (11061354)
2000
20
Internuclear ophthalmoplegia after insecticide exposure. (11103076)
2000
21
Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia. (10211481)
1999
22
So-called posterior internuclear ophthalmoplegia due to a pontine glioma: a clinicopathological study. (10399878)
1999
23
Internuclear ophthalmoplegia following minor head injury: a case report. (10070436)
1998
24
Neurological picture. Bilateral internuclear ophthalmoplegia in multiple sclerosis. (9408092)
1997
25
Toxic internuclear ophthalmoplegia related to antiobesity treatment. (1477455)
1992
26
Abduction nystagmus in internuclear ophthalmoplegia. (1455982)
1992
27
Bilateral internuclear ophthalmoplegia in a patient with Wernicke's encephalopathy. (1629372)
1992
28
Internuclear ophthalmoplegia in giant cell arteritis. (1548511)
1992
29
Early magnetic resonance imaging in acute traumatic internuclear ophthalmoplegia. (2234848)
1990
30
Internuclear ophthalmoplegia in the Chiari type II malformation. (2247233)
1990
31
Internuclear ophthalmoplegia in pernicious anaemia. (3147083)
1988
32
Abduction nystagmus in internuclear ophthalmoplegia. (3579224)
1987
33
Bilateral internuclear ophthalmoplegia with absence of convergent eye movements. Clinicopathologic correlation. (3009554)
1986
34
Internuclear ophthalmoplegia with narcotic overdosage. (3740812)
1986
35
Bilateral internuclear ophthalmoplegia due to hydrocephalus: a case report. (4069338)
1985
36
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984
37
Anterior internuclear ophthalmoplegia. (6526802)
1984
38
Internuclear ophthalmoplegia in patients with toxic coma frequency, prognostic value, diagnostic significance. (6655778)
1983
39
Bilateral internuclear ophthalmoplegia after intrathecal chemotherapy and cranial irradiation. (6172039)
1981
40
Internuclear ophthalmoplegia in Fabry's disease. (6794412)
1981
41
Unilateral internuclear ophthalmoplegia due to angiographic embolism through a primitive trigeminal artery. (7195492)
1981
42
Internuclear ophthalmoplegia caused by phenothiazine intoxication. (7247774)
1981
43
Disordered inhibition in internuclear ophthalmoplegia: analysis of eye movement recordings with computer simulations. (7363056)
1980
44
Excitatory termination of abducens internuclear neurons on medial rectus motoneurons: relationship to syndrome of internuclear ophthalmoplegia. (731294)
1978
45
Internuclear ophthalmoplegia. An electro-oculographic study of peak angular saccadic velocities. (990235)
1976
46
Internuclear ophthalmoplegia in progressive supranuclear palsy. (1159448)
1975
47
Internuclear ophthalmoplegia and associated abnormalities in eye motion timing (differential delays). (1167637)
1975
48
Paralytic pontine exotropia. A sign of acute unilateral pontine gaze palsy and internuclear ophthalmoplegia. (4472909)
1974
49
Abducting nystagmus in the medial longitudinal fasciculus (MLF) syndrome (internuclear ophthalmoplegia (INO)). (4718627)
1973
50
Unilateral internuclear ophthalmoplegia of vascular origin. (13361608)
1956

Genetic Variations for Internuclear Ophthalmoplegia

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Expression for genes affiliated with Internuclear Ophthalmoplegia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Internuclear Ophthalmoplegia

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Pathways for genes affiliated with Internuclear Ophthalmoplegia

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37NCBI BioSystems Database
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Pathways related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5AQP4, OMG

Compounds for genes affiliated with Internuclear Ophthalmoplegia

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GO Terms for genes affiliated with Internuclear Ophthalmoplegia

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16Gene Ontology
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Biological processes related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sensory perception of soundGO:0076059.4AQP4, HEXA

Products for genes affiliated with Internuclear Ophthalmoplegia

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Internuclear Ophthalmoplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet