MCID: INT042
MIFTS: 34

Internuclear Ophthalmoplegia malady

Eye diseases, Neuronal diseases categories

Summaries for Internuclear Ophthalmoplegia

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 Internuclear ophthalmoplegia (INO) is a disorder of conjugate lateral gaze in which the affected eye... more...

MalaCards: Internuclear Ophthalmoplegia is related to ophthalmoplegia and head injury. An important gene associated with Internuclear Ophthalmoplegia is AQP4 (aquaporin 4). The compound Water have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and testes, and related mouse phenotypes are hearing/vestibular/ear and behavior/neurological.

Aliases & Classifications for Internuclear Ophthalmoplegia

About this section
Sources:
9Disease Ontology, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 26ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Neuronal diseases


Aliases & Descriptions:

internuclear ophthalmoplegia 9 63


External Ids:

Disease Ontology9 DOID:538
ICD9CM28 378.86
SNOMED-CT59 49823009
MeSH36 D015835
ICD1026 H51.2

Related Diseases for Internuclear Ophthalmoplegia

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Internuclear Ophthalmoplegia:



Diseases related to internuclear ophthalmoplegia

Symptoms for Internuclear Ophthalmoplegia

About this section

Drugs & Therapeutics for Internuclear Ophthalmoplegia

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Internuclear Ophthalmoplegia

Drug clinical trials:

Search ClinicalTrials for Internuclear Ophthalmoplegia

Search NIH Clinical Center for Internuclear Ophthalmoplegia

Search CenterWatch for Internuclear Ophthalmoplegia

Genetic Tests for Internuclear Ophthalmoplegia

About this section

Anatomical Context for Internuclear Ophthalmoplegia

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Internuclear Ophthalmoplegia:

34
Eye, Brain, Testes

Animal Models for Internuclear Ophthalmoplegia or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Internuclear Ophthalmoplegia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.1HEXA, AQP4
2MP:00053869.1HEXA, AQP4
3MP:00053679.0HEXA, AQP4
4MP:00053918.8HEXA, AQP4

Publications for Internuclear Ophthalmoplegia

About this section
Sources:
53PubMed
See all sources

Articles related to Internuclear Ophthalmoplegia:

(show top 50)    (show all 236)
idTitleAuthorsYear
1
Bilateral internuclear ophthalmoplegia associated with pediatric brain tumor progression: a case series and review of the literature. (24048548)
2013
2
Acute onset of upbeat nystagmus, exotropia, and internuclear ophthalmoplegia--a tell-tale of ponto-mesencephalic infarct. (23830476)
2013
3
Pediatric internuclear ophthalmoplegia. (23470988)
2013
4
Motion diplopia in an isolated unilateral internuclear ophthalmoplegia: a new neurological symptom? (22790327)
2013
5
An unusual aetiology for internuclear ophthalmoplegia. (23737577)
2013
6
Rapid reversal of wall-eyed bilateral internuclear ophthalmoplegia. (22410451)
2012
7
Unilateral internuclear ophthalmoplegia after minor head injury. (22461944)
2012
8
Neurological picture. Internuclear ophthalmoplegia following African tick bite fever. (21421770)
2011
9
Patterns of dissociate torsional-vertical nystagmus in internuclear ophthalmoplegia. (21951004)
2011
10
Bilateral Internuclear Ophthalmoplegia in a Patient with Devic's Neuromyelitis Optica. (21113284)
2010
11
Progressive supranuclear palsy with wall-eyed bilateral internuclear ophthalmoplegia syndrome. (18541806)
2008
12
Abducens-oculomotor synkinesis associated with internuclear ophthalmoplegia and acquired abducens nerve palsy. (16915907)
2006
13
Reversible bilateral internuclear ophthalmoplegia associated with FK506. (15090580)
2004
14
Internuclear ophthalmoplegia and torsional nystagmus: an MRI correlate. (14571025)
2003
15
Prognosis of ischemic internuclear ophthalmoplegia. (12208716)
2002
16
Internuclear ophthalmoplegia as the first sign of neuroborreliosis. (12420716)
2002
17
Reversible bilateral internuclear ophthalmoplegia following head injury. (11167289)
2001
18
Abduction paresis with rostral pontine and/or mesencephalic lesions: Pseudoabducens palsy and its relation to the so-called posterior internuclear ophthalmoplegia of Lutz. (11570979)
2001
19
Primary isolated brainstem injury producing internuclear ophthalmoplegia. (11708549)
2001
20
Internuclear ophthalmoplegia with skew deviation. Two cases with an isolated circumscribed lesion of the medial longitudinal fasciculus. (11096232)
2000
21
Partial unilateral third nerve palsy and bilateral internuclear ophthalmoplegia: an unusual presentation of multiple sclerosis. (11040928)
2000
22
Pontine lesion of the abducens fasciculus producing so-called posterior internuclear ophthalmoplegia. (9018039)
1997
23
Toxic internuclear ophthalmoplegia related to antiobesity treatment. (1477455)
1992
24
A syndrome of early onset spinocerebellar ataxia with optic atrophy, internuclear ophthalmoplegia, dementia, and startle myoclonus in a Sri Lankan family. (1607894)
1992
25
Bilateral internuclear ophthalmoplegia after smoking "crack" cocaine. (1838554)
1991
26
Internuclear ophthalmoplegia in acquired immunodeficiency syndrome. (2802452)
1989
27
Internuclear ophthalmoplegia in tuberculous meningitis. (2781611)
1989
28
Unilateral internuclear ophthalmoplegia, migraine, and supratentorial arteriovenous malformation. (3618721)
1987
29
Bilateral internuclear ophthalmoplegia in systemic lupus erythematosus. (2956286)
1987
30
Traumatic internuclear ophthalmoplegia. (2958510)
1987
31
Iatrogenic internuclear ophthalmoplegia. (3746320)
1986
32
Bilateral internuclear ophthalmoplegia due to hydrocephalus: a case report. (4069338)
1985
33
Anterior internuclear ophthalmoplegia. (4055693)
1985
34
Paresis of lateral gaze alternating with so-called posterior internuclear ophthalmoplegia. A partial paramedian pontine reticular formation-abducens nucleus syndrome. (3998774)
1985
35
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984
36
Bilateral internuclear ophthalmoplegia reversed by naloxone. (6830474)
1983
37
Drug-induced internuclear ophthalmoplegia. (6831328)
1983
38
Internuclear ophthalmoplegia in patients with toxic coma frequency, prognostic value, diagnostic significance. (6655778)
1983
39
Internuclear ophthalmoplegia after head trauma. (7258960)
1981
40
Bilateral internuclear ophthalmoplegia after intrathecal chemotherapy and cranial irradiation. (6172039)
1981
41
Internuclear ophthalmoplegia: recovery and plasticity. (7440105)
1980
42
Internuclear ophthalmoplegia following head injury. (7359205)
1980
43
Internuclear ophthalmoplegia. I. Saccades and dissociated nystagmus. (666604)
1978
44
Experimental internuclear ophthalmoplegia. (403929)
1977
45
An electrooculographic study of internuclear ophthalmoplegia. (617577)
1977
46
Abducting nystagmus in the medial longitudinal fasciculus (MLF) syndrome (internuclear ophthalmoplegia (INO)). (4718627)
1973
47
Vestibular influences on internuclear ophthalmoplegia. (5100343)
1971
48
Unilateral internuclear ophthalmoplegia. Report of a case including pathology. (5937495)
1966
49
Lateral gaze and convergence in internuclear ophthalmoplegia: a note on examination. (5948645)
1966
50
Unilateral internuclear ophthalmoplegia; a report of seven clinical cases and the postmortem findings in one case. (14788115)
1950

Variations for Internuclear Ophthalmoplegia

About this section

Expression for genes affiliated with Internuclear Ophthalmoplegia

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Internuclear Ophthalmoplegia

Search GEO for disease gene expression data for Internuclear Ophthalmoplegia.

Pathways for genes affiliated with Internuclear Ophthalmoplegia

About this section

Compounds for genes affiliated with Internuclear Ophthalmoplegia

About this section
Sources:
25HMDB
See all sources

Compounds related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1Water259.1HEXA, AQP4

GO Terms for genes affiliated with Internuclear Ophthalmoplegia

About this section
Sources:
17Gene Ontology
See all sources

Biological processes related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sensory perception of soundGO:0076059.1HEXA, AQP4

Products for genes affiliated with Internuclear Ophthalmoplegia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Internuclear Ophthalmoplegia

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet