MCID: INT042
MIFTS: 29

Internuclear Ophthalmoplegia malady

Eye diseases category

Summaries for Internuclear Ophthalmoplegia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Internuclear ophthalmoplegia (INO) is a disorder of conjugate lateral gaze in which the affected eye... more...

MalaCards: Internuclear Ophthalmoplegia is related to myasthenia gravis and ophthalmoplegia. An important gene associated with Internuclear Ophthalmoplegia is AQP4 (aquaporin 4), and among its related pathways is Spinal Cord Injury. Affiliated tissues include eye, brain and testes.

Aliases & Classifications for Internuclear Ophthalmoplegia

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8Disease Ontology, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

internuclear ophthalmoplegia 8 60


External Ids:

Disease Ontology8 DOID:538
ICD9CM27 378.86
SNOMED-CT56 49823009
MeSH34 D015835
ICD1025 H51.2

Related Diseases for Internuclear Ophthalmoplegia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Internuclear Ophthalmoplegia:



Diseases related to internuclear ophthalmoplegia

Clinical Features for Internuclear Ophthalmoplegia

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Drugs & Therapeutics for Internuclear Ophthalmoplegia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Internuclear Ophthalmoplegia

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Anatomical Context for Internuclear Ophthalmoplegia

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32MalaCards
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MalaCards organs/tissues related to Internuclear Ophthalmoplegia:

32
Eye, Brain, Testes

Animal Models for Internuclear Ophthalmoplegia or affiliated genes

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Publications for Internuclear Ophthalmoplegia

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50PubMed
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Articles related to Internuclear Ophthalmoplegia:

(show top 50)    (show all 240)
idTitleAuthorsYear
1
Pediatric internuclear ophthalmoplegia. (23470988)
2013
2
Motion diplopia in an isolated unilateral internuclear ophthalmoplegia: a new neurological symptom? (22790327)
2013
3
Evolution of symmetric upbeat into dissociated torsional-upbeat nystagmus in internuclear ophthalmoplegia. (23664561)
2013
4
Rapid reversal of wall-eyed bilateral internuclear ophthalmoplegia. (22410451)
2012
5
Bilateral internuclear ophthalmoplegia with unilateral horizontal gaze paresis. (22728510)
2012
6
Ocular tilt reaction, internuclear ophthalmoplegia, and torsional nystagmus following mitral commissurotomy. (23084391)
2012
7
A small pontine infarct on DWI as a lesion responsible for wall-eyed bilateral internuclear ophthalmoplegia syndrome. (21655962)
2012
8
Pure isolated internuclear ophthalmoplegia. (21841349)
2011
9
Ocular tilt reaction and internuclear ophthalmoplegia associated with venous sinus thrombosis: an unusual case. (19091852)
2010
10
Wall-eyed bilateral internuclear ophthalmoplegia after ruptured aneurysm. (20457967)
2010
11
Carbon Monoxide Poisoning: A Patient with Bilateral Internuclear Ophthalmoplegia and Exotropia. (19645381)
2009
12
Identification of internuclear ophthalmoplegia signs in multiple sclerosis patients. Saccade test analysis. (18446308)
2008
13
Left vertebral artery dissection causing bilateral internuclear ophthalmoplegia. (18826742)
2008
14
Botulinum toxin in the management of internuclear ophthalmoplegia. (17498988)
2007
15
Internuclear ophthalmoplegia associated with transient torsional nystagmus. (12189654)
2002
16
Reversible bilateral internuclear ophthalmoplegia following head injury. (11167289)
2001
17
Abduction paresis with rostral pontine and/or mesencephalic lesions: Pseudoabducens palsy and its relation to the so-called posterior internuclear ophthalmoplegia of Lutz. (11570979)
2001
18
Primary isolated brainstem injury producing internuclear ophthalmoplegia. (11708549)
2001
19
Bilateral internuclear ophthalmoplegia following mild head injury. (11417420)
2001
20
Wall-eyed bilateral internuclear ophthalmoplegia in central nervous system cryptococcosis. (10380136)
1999
21
Unilateral internuclear ophthalmoplegia and ipsiversive torsional nystagmus. (8803819)
1996
22
Cervical radiculopathy and bilateral internuclear ophthalmoplegia caused by temporal arteritis. (8006670)
1994
23
Internuclear ophthalmoplegia in sickle cell trait. (8032481)
1994
24
Transient bilateral internuclear ophthalmoplegia after minor head-trauma. (8444330)
1993
25
Severe destruction of the neural integration mechanism for upward eye movements in bilateral internuclear ophthalmoplegia. (8295369)
1993
26
Saccades in internuclear ophthalmoplegia: are abduction disorders related to interocular disconjugacy? (8445398)
1993
27
Magnetic resonance imaging correlates of internuclear ophthalmoplegia. (2265923)
1990
28
Internuclear ophthalmoplegia in pernicious anemia. (2495069)
1989
29
Bilateral internuclear ophthalmoplegia due to acute cervical hyperextension without head trauma. (2526155)
1989
30
Vertical vestibulo-ocular reflex, smooth pursuit and eye-head tracking dysfunction in internuclear ophthalmoplegia. (3208059)
1988
31
Internuclear ophthalmoplegia. (3122648)
1987
32
Iatrogenic internuclear ophthalmoplegia. (3746320)
1986
33
Bilateral internuclear ophthalmoplegia from doxepin overdose. (6538026)
1984
34
Internuclear ophthalmoplegia and "optic neuritis": paraneoplastic effects of bronchial carcinoma. (6539443)
1984
35
Bilateral internuclear ophthalmoplegia reversed by naloxone. (6830474)
1983
36
Bilateral internuclear ophthalmoplegia in meningoencephalitis. (6653917)
1983
37
The existence of posterior internuclear ophthalmoplegia. (6571426)
1983
38
Amitriptyline: another cause of internuclear ophthalmoplegia with coma. (7114819)
1982
39
Reversible bilateral internuclear ophthalmoplegia due to head trauma: a case report. (7215401)
1981
40
Internuclear ophthalmoplegia: recovery and plasticity. (7440105)
1980
41
Experimental internuclear ophthalmoplegia. (403929)
1977
42
Internuclear ophthalmoplegia following cervical manipulation. (889325)
1977
43
Bilateral anterior internuclear ophthalmoplegia as false localization sign. (1036240)
1976
44
Letter: Unilateral internuclear ophthalmoplegia in systemic lupus erythematosus. (1137517)
1975
45
Bilateral internuclear ophthalmoplegia after trauma. (4835980)
1974
46
Vestibular influences on internuclear ophthalmoplegia. (5100343)
1971
47
Aeromedical consultation service case report: uniocular oscillopsia associated with internuclear ophthalmoplegia. (5099869)
1971
48
Lateral gaze and convergence in internuclear ophthalmoplegia: a note on examination. (5948645)
1966
49
Internuclear ophthalmoplegia; a review of fifty-eight cases. (13636562)
1959
50
The surgical treatment of exotropia resulting from anterior internuclear ophthalmoplegia. A practical evaluation of some surgical techniques. (14789933)
1950

Genetic Variations for Internuclear Ophthalmoplegia

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Expression for genes affiliated with Internuclear Ophthalmoplegia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Internuclear Ophthalmoplegia

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Pathways for genes affiliated with Internuclear Ophthalmoplegia

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37NCBI BioSystems Database
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Pathways related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5AQP4, OMG

Compounds for genes affiliated with Internuclear Ophthalmoplegia

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GO Terms for genes affiliated with Internuclear Ophthalmoplegia

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16Gene Ontology
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Biological processes related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sensory perception of soundGO:0076059.4AQP4, HEXA

Products for genes affiliated with Internuclear Ophthalmoplegia

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Sources for Internuclear Ophthalmoplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet