MCID: INT042
MIFTS: 34

Internuclear Ophthalmoplegia malady

Eye diseases, Neuronal diseases categories
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Summaries for Internuclear Ophthalmoplegia

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Wikipedia:65 Internuclear ophthalmoplegia (INO) is a disorder of conjugate lateral gaze in which the affected eye... more...

MalaCards based summary: Internuclear Ophthalmoplegia is related to ophthalmoplegia and multiple sclerosis. An important gene associated with Internuclear Ophthalmoplegia is AQP4 (aquaporin 4). The compound Water have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and testes, and related mouse phenotypes are hearing/vestibular/ear and behavior/neurological.

Aliases & Classifications for Internuclear Ophthalmoplegia

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Internuclear Ophthalmoplegia, Aliases & Descriptions:

Name: Internuclear Ophthalmoplegia 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Neuronal diseases


External Ids:

Disease Ontology8 DOID:538
MeSH34 D015835
SNOMED-CT57 49823009
ICD9CM27 378.86
ICD1025 H51.2

Related Diseases for Internuclear Ophthalmoplegia

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Graphical network of the top 20 diseases related to Internuclear Ophthalmoplegia:



Diseases related to internuclear ophthalmoplegia

Symptoms for Internuclear Ophthalmoplegia

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Drugs & Therapeutics for Internuclear Ophthalmoplegia

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Drug clinical trials:

Search ClinicalTrials for Internuclear Ophthalmoplegia

Search NIH Clinical Center for Internuclear Ophthalmoplegia

Genetic Tests for Internuclear Ophthalmoplegia

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Anatomical Context for Internuclear Ophthalmoplegia

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MalaCards organs/tissues related to Internuclear Ophthalmoplegia:

32
Eye, Brain, Testes

Animal Models for Internuclear Ophthalmoplegia or affiliated genes

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MGI Mouse Phenotypes related to Internuclear Ophthalmoplegia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.1HEXA, AQP4
2MP:00053869.1HEXA, AQP4
3MP:00053679.0HEXA, AQP4
4MP:00053918.8HEXA, AQP4

Publications for Internuclear Ophthalmoplegia

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Articles related to Internuclear Ophthalmoplegia:

(show top 50)    (show all 245)
idTitleAuthorsYear
1
Bilateral ptosis with wall-eyed bilateral internuclear ophthalmoplegia and vertical gaze paralysis. (24870222)
2014
2
Vertical gaze-evoked nystagmus and internuclear ophthalmoplegia as sole manifestations in paramedian pontine infarction. (24770935)
2014
3
Bilateral internuclear ophthalmoplegia associated with pediatric brain tumor progression: a case series and review of the literature. (24048548)
2013
4
Acute onset of upbeat nystagmus, exotropia, and internuclear ophthalmoplegia--a tell-tale of ponto-mesencephalic infarct. (23830476)
2013
5
Pediatric internuclear ophthalmoplegia. (23470988)
2013
6
Motion diplopia in an isolated unilateral internuclear ophthalmoplegia: a new neurological symptom? (22790327)
2013
7
An unusual aetiology for internuclear ophthalmoplegia. (23737577)
2013
8
Rapid reversal of wall-eyed bilateral internuclear ophthalmoplegia. (22410451)
2012
9
Unilateral internuclear ophthalmoplegia after minor head injury. (22461944)
2012
10
Neurological picture. Internuclear ophthalmoplegia following African tick bite fever. (21421770)
2011
11
Patterns of dissociate torsional-vertical nystagmus in internuclear ophthalmoplegia. (21951004)
2011
12
Bilateral Internuclear Ophthalmoplegia in a Patient with Devic's Neuromyelitis Optica. (21113284)
2010
13
Progressive supranuclear palsy with wall-eyed bilateral internuclear ophthalmoplegia syndrome. (18541806)
2008
14
Abducens-oculomotor synkinesis associated with internuclear ophthalmoplegia and acquired abducens nerve palsy. (16915907)
2006
15
Internuclear ophthalmoplegia. (16606784)
2006
16
Prognosis of ischemic internuclear ophthalmoplegia. (12208716)
2002
17
Internuclear ophthalmoplegia as the first sign of neuroborreliosis. (12420716)
2002
18
Reversible bilateral internuclear ophthalmoplegia following head injury. (11167289)
2001
19
Abduction paresis with rostral pontine and/or mesencephalic lesions: Pseudoabducens palsy and its relation to the so-called posterior internuclear ophthalmoplegia of Lutz. (11570979)
2001
20
Primary isolated brainstem injury producing internuclear ophthalmoplegia. (11708549)
2001
21
Internuclear ophthalmoplegia with skew deviation. Two cases with an isolated circumscribed lesion of the medial longitudinal fasciculus. (11096232)
2000
22
Partial unilateral third nerve palsy and bilateral internuclear ophthalmoplegia: an unusual presentation of multiple sclerosis. (11040928)
2000
23
Pontine lesion of the abducens fasciculus producing so-called posterior internuclear ophthalmoplegia. (9018039)
1997
24
Toxic internuclear ophthalmoplegia related to antiobesity treatment. (1477455)
1992
25
Abduction nystagmus in internuclear ophthalmoplegia. (1455982)
1992
26
Bilateral internuclear ophthalmoplegia after smoking "crack" cocaine. (1838554)
1991
27
Internuclear ophthalmoplegia in acquired immunodeficiency syndrome. (2802452)
1989
28
Internuclear ophthalmoplegia in tuberculous meningitis. (2781611)
1989
29
Unilateral internuclear ophthalmoplegia, migraine, and supratentorial arteriovenous malformation. (3618721)
1987
30
Bilateral internuclear ophthalmoplegia in systemic lupus erythematosus. (2956286)
1987
31
Iatrogenic internuclear ophthalmoplegia. (3746320)
1986
32
Bilateral internuclear ophthalmoplegia due to hydrocephalus: a case report. (4069338)
1985
33
Anterior internuclear ophthalmoplegia. (4055693)
1985
34
Paresis of lateral gaze alternating with so-called posterior internuclear ophthalmoplegia. A partial paramedian pontine reticular formation-abducens nucleus syndrome. (3998774)
1985
35
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984
36
Bilateral internuclear ophthalmoplegia reversed by naloxone. (6830474)
1983
37
Drug-induced internuclear ophthalmoplegia. (6831328)
1983
38
Internuclear ophthalmoplegia in patients with toxic coma frequency, prognostic value, diagnostic significance. (6655778)
1983
39
Internuclear ophthalmoplegia after head trauma. (7258960)
1981
40
Bilateral internuclear ophthalmoplegia after intrathecal chemotherapy and cranial irradiation. (6172039)
1981
41
Internuclear ophthalmoplegia: recovery and plasticity. (7440105)
1980
42
Internuclear ophthalmoplegia following head injury. (7359205)
1980
43
Internuclear ophthalmoplegia. I. Saccades and dissociated nystagmus. (666604)
1978
44
Experimental internuclear ophthalmoplegia. (403929)
1977
45
An electrooculographic study of internuclear ophthalmoplegia. (617577)
1977
46
Abducting nystagmus in the medial longitudinal fasciculus (MLF) syndrome (internuclear ophthalmoplegia (INO)). (4718627)
1973
47
Vestibular influences on internuclear ophthalmoplegia. (5100343)
1971
48
Unilateral internuclear ophthalmoplegia. Report of a case including pathology. (5937495)
1966
49
Lateral gaze and convergence in internuclear ophthalmoplegia: a note on examination. (5948645)
1966
50
Unilateral internuclear ophthalmoplegia; a report of seven clinical cases and the postmortem findings in one case. (14788115)
1950

Variations for Internuclear Ophthalmoplegia

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Expression for genes affiliated with Internuclear Ophthalmoplegia

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Expression patterns in normal tissues for genes affiliated with Internuclear Ophthalmoplegia

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Pathways for genes affiliated with Internuclear Ophthalmoplegia

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Compounds for genes affiliated with Internuclear Ophthalmoplegia

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Compounds related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1Water249.1HEXA, AQP4

GO Terms for genes affiliated with Internuclear Ophthalmoplegia

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Biological processes related to Internuclear Ophthalmoplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sensory perception of soundGO:0076059.1HEXA, AQP4

Products for genes affiliated with Internuclear Ophthalmoplegia

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Sources for Internuclear Ophthalmoplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet