MCID: INT065
MIFTS: 26

Interstitial Keratitis malady

Eye diseases category

Summaries for Interstitial Keratitis

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Interstitial Keratitis (IK) basically means corneal scarring due to chronic inflammation of the corneal... more...

MalaCards: Interstitial Keratitis is related to keratitis and syphilis. An important gene associated with Interstitial Keratitis is COL9A1 (collagen, type IX, alpha 1). Affiliated tissues include eye, bone and testes.

Aliases & Classifications for Interstitial Keratitis

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Sources:
9Disease Ontology, 63UMLS, 28ICD9CM, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

interstitial keratitis 9 63


External Ids:

Disease Ontology9 DOID:9857
SNOMED-CT59 1763009, 193784002
ICD9CM28 370.50

Related Diseases for Interstitial Keratitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Interstitial Keratitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 39)
idRelated DiseaseScoreTop Affiliating Genes
1keratitis11.1
2syphilis10.6
3glaucoma10.4
4congenital syphilis10.4
5cogan's syndrome10.4
6hidradenitis suppurativa10.3
7diffuse interstitial keratitis10.3
8hidradenitis10.3
9periostitis10.3
10uveitis10.3
11blindness10.3
12aortitis10.2
13late congenital syphilis10.2
14sarcoidosis10.2
15idiopathic linear interstitial keratitis10.2
16onchocerciasis10.1
17lyme disease10.1
18ophthalmia neonatorum10.1
19posterior uveitis10.1
20choroiditis10.1
21sensorineural hearing loss10.1
22vaccinia10.1
23mucocutaneous leishmaniasis10.1
24amyloidosis10.1
25arthritis10.1
26cataract10.1
27cervicitis10.1
28chorioretinitis10.1
29herpes simplex10.1
30hypothyroidism10.1
31leishmaniasis10.1
32malaria10.1
33rheumatoid arthritis10.1
34smallpox10.1
35thyroiditis10.1
36gapo syndrome10.1
37mastocytosis10.1
38periarteritis nodosa10.1
39spasticity10.1

Graphical network of the top 20 diseases related to Interstitial Keratitis:



Diseases related to interstitial keratitis

Symptoms for Interstitial Keratitis

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Drugs & Therapeutics for Interstitial Keratitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Interstitial Keratitis

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Anatomical Context for Interstitial Keratitis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Interstitial Keratitis:

34
Eye, Bone, Testes, Bone marrow, Thyroid, T cells

Animal Models for Interstitial Keratitis or affiliated genes

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Publications for Interstitial Keratitis

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Sources:
53PubMed
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Articles related to Interstitial Keratitis:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
Interstitial keratitis secondary to severe hidradenitis suppurativa responding to adalimumab. (22146546)
2012
2
Interstitial keratitis secondary to severe hidradenitis suppurativa: a case report and literature review. (20628295)
2010
3
GAPO syndrome: a case associated with bilateral interstitial keratitis and hypothyroidism. (20032780)
2010
4
Interstitial keratitis following varicella vaccination. (19204247)
2009
5
Immunohistochemistry and electron microscopy of retrocorneal scrolls in syphilitic interstitial keratitis. (17963106)
2007
6
Syphilitic interstitial keratitis: treatment with immunosuppressive drug combination therapy. (15220743)
2004
7
Results of penetrating keratoplasty in syphilitic interstitial keratitis. (14750229)
2003
8
Images in clinical medicine. Interstitial keratitis as the initial expression of syphilitic reactivation. (12050340)
2002
9
Gold induced interstitial keratitis. (11702733)
2001
10
Etiology of immune stromal (interstitial) keratitis. (9603383)
1998
11
The retrocorneal ridge in syphilitic and herpetic interstitial keratitis: an electron-microscopic study. (7046592)
1982
12
Collagenase levels in a new model of experimental herpetic interstitial keratitis. (6246865)
1980
13
Alterations of Descemet's membrane in interstitial keratitis. (937431)
1976
14
Immunologic study of nonsyphilitic interstitial keratitis with vestibuloauditory symptoms. (1099914)
1975
15
Late glaucoma after interstitial keratitis. (1110206)
1975
16
Metachromic study of ground substance in anaphylactic interstitial keratitis]. (4121684)
1973
17
Retained Descemet's membrane after keratoplasty for old interstitial keratitis. (4577690)
1973
18
Cogan-I-syndrome. Interstitial keratitis with sudden deafness. (4539269)
1972
19
Electron microscopy of late interstitial keratitis. (4560392)
1972
20
Testing for congenital syphilis in interstitial keratitis. (4938990)
1971
21
Penetrating keratoplasty in interstitial keratitis. (4891697)
1969
22
Interstitial keratitis and glaucoma. (4894905)
1969
23
Interstitial keratitis associated with hidradenitis suppurativa. (4164818)
1967
24
Interstitial keratitis. (5928927)
1966
25
Ring-forming interstitial keratitis in man. (14015167)
1963
26
Late glaucoma associated with inactive syphilitic interstitial keratitis. (13918184)
1962
27
Syndrome of nonsyphilitic interstitial keratitis and vestibuloauditory symptoms; a long-term follow-up. (13636563)
1959
28
Interstitial keratitis; a case report on preventable blindness. (13541926)
1958
29
Interstitial keratitis treated with cortisone. (13176690)
1954
30
Nonsyphilitic interstitial keratitis and bilateral deafness (Cogan's syndrome) associated with essential polyangitis (periarteritis nodosa); a review of the syndrome with consideration of a possible pathogenic mechanism. (13046665)
1953
31
Penicillin alone and penicillin and fever therapy of interstitial keratitis due to syphilis]. (13155658)
1953
32
Some observations on the treatment of interstitial keratitis with penicillin, malaria, and cortisone. (13104798)
1953
33
Retro-corneal hyaline bands in interstitial keratitis. (13059276)
1953
34
Syphilitic interstitial keratitis after five years of seronegativity; a case report. (14903421)
1952
35
The effect of local cortisone in the treatment of syphilitic interstitial keratitis; preliminary report. (14885621)
1951
36
Endocrine studies of patients with syphilitic interstitial keratitis. (14878089)
1951
37
Topical cortisone in interstitial keratitis; a case report. (14894587)
1951
38
Some aspects of interstitial keratitis. (15410175)
1950
39
Penicillin in interstitial keratitis. (15402409)
1950
40
Interstitial keratitis and vestibuloauditory symptoms following vaccination. (18111345)
1949
41
The treatment of syphilitic interstitial keratitis; outline of a method of treatment suitable for a rapid treatment center or small hospital. (18889038)
1948
42
A case of interstitial keratitis after a gluteal abscess. (20250969)
1947
43
Interstitial keratitis treated with subconjunctival injections of penicillin. (21004339)
1945
44
Lipin Interstitial Keratitis. (16693032)
1934
45
Interstitial Keratitis, with Marked Radial Deep Corneal Striation (Corneal A9dema). (20909967)
1927
46
Case of Interstitial Keratitis accompanied by Periostitis of the Tibia due to Congenital Syphilis. (19985313)
1926
47
THE INFLUENCE OF TRAUMA UPON THE ONSET OF INTERSTITIAL KERATITIS. (18168234)
1922
48
Chronic Interstitial Keratitis, Atrophy and Spasticity of the Left Leg. (19982589)
1922
49
Interstitial Keratitis of Luetic Origin. (16692276)
1913
50
Diffuse interstitial keratitis in acquired syphilis. (16692142)
1908

Variations for Interstitial Keratitis

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Expression for genes affiliated with Interstitial Keratitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Interstitial Keratitis

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Pathways for genes affiliated with Interstitial Keratitis

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Compounds for genes affiliated with Interstitial Keratitis

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GO Terms for genes affiliated with Interstitial Keratitis

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Products for genes affiliated with Interstitial Keratitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Interstitial Keratitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet