Interstitial Lung Disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

ILD MCID: INT066 MIFTS: 53	Interstitial Lung Disease (ILD) malady Respiratory diseases category
131 genes, 14 tissues, 140 related diseases, clinical trials.

Summaries for Interstitial Lung Disease

Sources:
³³MedlinePlus, ⁶³Wikipedia, ³²MalaCards
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MedlinePlus:³³ Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. the inflammation and scarring make it hard to get enough oxygen. the scarring is called pulmonary fibrosis. breathing in dust or other particles in the air is responsible for some types of interstitial lung diseases. specific types include black lung disease among coal miners, from inhaling coal dust farmer's lung, from inhaling farm dust asbestosis, from inhaling asbestos fibers siderosis, from inhaling iron from mines or welding fumes silicosis, from inhaling silica dust other causes include autoimmune diseases or occupational exposures to molds, gases, or fumes. some types of interstitial lung disease have no known cause. treatment depends on the type of exposure and the stage of the disease. it may involve medicines, oxygen therapy, or a lung transplant in severe cases.

MalaCards: Interstitial Lung Disease, also known as lung diseases, interstitial, is related to rheumatoid arthritis and arthritis. An important gene associated with Interstitial Lung Disease is SFTPC (surfactant protein C), and among its related pathways are PEDF Induced Signaling and Akt Signaling. The compounds calcium and dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotype immune system.

Wikipedia:⁶³ Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a... more...

Aliases & Classifications for Interstitial Lung Disease

Sources:
⁸Disease Ontology, ¹⁰DISEASES, ⁴⁴Novoseek, ³³MedlinePlus, ⁶⁰UMLS, ³⁴MeSH, ⁵⁶SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases

Aliases & Descriptions:

interstitial lung disease ⁸ ¹⁰

lung diseases, interstitial ⁶⁰

lung diseases interstitial ⁴⁴

interstitial lung diseases ³³

ild ⁸

External Ids:

Disease Ontology⁸ DOID:3082

SNOMED-CT⁵⁶ 233703007, 64667001

MeSH³⁴ D017563

UMLS⁶⁰ C0206062

Related Diseases for Interstitial Lung Disease

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
See all sources

Diseases related to Interstitial Lung Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 140)

id	Related Disease	Score	Top Affiliating Genes
1	rheumatoid arthritis	31.2	CCL18, SFTPD, S100A9, CD70, CD27, CXCL5
2	arthritis	31.2	S100A9, CXCL5, CXCL9
3	pneumonia	31.0	CCL22, CCL18, SFTPC, SFTPD, SFTPB, CXCL5
4	pulmonary fibrosis	30.9	SFTPD, SFTPC, CCL18, CCL22
5	idiopathic pulmonary fibrosis	30.7	CCL22, SFTPC, SFTPD, SFTPB, CXCL5, CXCL9
6	melanoma	30.4	ITGA3, CD70, CD27, CXCL5, CXCL9
7	skin disease	30.4	CXCL9
8	respiratory failure	30.4	SFTPC, SFTPD, SFTPB
9	lupus erythematosus	30.4	CD70
10	sarcoidosis	30.2	CCL18, SFTPD, S100A9, CHIT1, CD27, CXCL5
11	cystic fibrosis	30.2	S100A9, SFTPB, SFTPD, SFTPC, CCL22
12	extrinsic allergic alveolitis	30.2	CXCL5, SFTPD
13	asthma	30.0	CCL22, SFTPC, SFTPD, SFTPB, SCGB3A2, CHIT1
14	influenza	30.0	CCL18, SFTPD, CD27, CXCL9
15	pulmonary sarcoidosis	30.0	CXCL9, CXCL5, SFTPD
16	multiple sclerosis	30.0	CHIT1, CD27, CXCL9
17	uveitis	30.0	CXCL9
18	tuberculosis	30.0	CXCL9, SFTPD
19	non-small cell lung carcinoma	30.0	SFTPB, SFTPD, SFTPC
20	dermatomyositis	11.0
21	rheumatoid lung disease	10.8
22	connective tissue disease	10.8
23	lung cancer	10.8
24	scleroderma	10.7
25	hypertension	10.7
26	bronchiolitis	10.7
27	respiratory bronchiolitis-associated interstitial lung disease	10.7
28	myopathy	10.4
29	myositis	10.4
30	desquamative interstitial pneumonia	10.4
31	common variable immunodeficiency	10.4
32	pulmonary systemic sclerosis	10.4
33	interstitial emphysema	10.3
34	mixed connective tissue disease	10.3
35	adenocarcinoma	10.3
36	esophageal disease	10.3
37	esophagitis	10.3
38	idiopathic interstitial pneumonia	10.3
39	lung adenocarcinoma	10.3
40	obstructive lung disease	10.3
41	pneumothorax	10.3
42	vascular disease	10.3
43	colorectal cancer	10.3
44	children's interstitial lung disease	10.3
45	interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital	10.3
46	nonspecific interstitial pneumonia	10.3
47	diffuse scleroderma	10.3
48	erdheim-chester disease	10.3
49	adult dermatomyositis	10.3
50	hermansky-pudlak syndrome	10.3

Graphical network of the top 20 diseases related to Interstitial Lung Disease:

Clinical Features for Interstitial Lung Disease

Drugs & Therapeutics for Interstitial Lung Disease

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶⁰UMLS, ⁴⁰NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Interstitial Lung Disease

Drug clinical trials:

Search ClinicalTrials for Interstitial Lung Disease

Search NIH Clinical Center for Interstitial Lung Disease

Search CenterWatch for Interstitial Lung Disease

Genetic Tests for Interstitial Lung Disease

Anatomical Context for Interstitial Lung Disease

Sources:
³²MalaCards
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MalaCards organs/tissues related to Interstitial Lung Disease:

³²

Lung, Testes, Monocytes, Skin, Endothelial, Brain, T cells, B cells, Thyroid, Heart, Breast, Lymph node, Bone, Smooth muscle

Animal Models for Interstitial Lung Disease or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Interstitial Lung Disease:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system phenotype	MP:0005387	10.6	IL27, CXCL9, CD27, CD70, CHIT1, ITGA3

Publications for Interstitial Lung Disease

Sources:
⁵⁰PubMed
See all sources

Articles related to Interstitial Lung Disease:

(show top 50) (show all 729)

id	Title	Authors	Year
1	Riociguat for interstitial lung disease and pulmonary hypertension: a pilot trial. (22936711)	Hoeper M.M.... Behr J.	2013
2	Predictors of mortality in rheumatoid arthritis-related interstitial lung disease. (24372981)	Assayag D.... Ryerson C.J.	2013
3	Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease. (23915349)	Lindahl G.E.... Renzoni E.A.	2013
4	An approach to the development of interstitial lung disease in dermatomyositis: a study of 230 cases in China. (23569020)	Wu H.... Xu J.	2013
5	Autoreactive bronchus-associated lymphoid tissue in interstitial lung disease: friend or foe? (23544886)	Jordan M.... Haczku A.	2013
6	An unusual case of cystic interstitial lung disease. (23562001)	Stefani A.... Morandi U.	2013
7	Uniportal VATS for pneumothorax and interstitial lung disease. (24040528)	Salati M.... Brunelli A.	2013
8	Mycophenolate versus cyclophosphamide for progressive interstitial lung disease associated with systemic sclerosis: a 2-year case control study. (23925736)	Panopoulos S.T.... Sfikakis P.P.	2013
9	Influenza vaccine-induced interstitial lung disease. (23370803)	Watanabe S.... Fujimura M.	2013
10	Fibrosing interstitial pneumonia predicts survival in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). (23791462)	Solomon J.J.... Brown K.K.	2013
11	Interstitial lung disease in a child with antisynthetase syndrome. (23652349)	Hayes D.... Nicol K.K.	2013
12	Effects of inpatient pulmonary rehabilitation in patients with interstitial lung disease. (23100507)	Huppmann P.... Kenn K.	2013
13	Pulmonary rehabilitation and interstitial lung disease: aiding the referral decision. (23595005)	Johnson-Warrington V.... Singh S.	2013
14	The clinical significance of HRCT in evaluation of patients with rheumatoid arthritis-associated interstitial lung disease: a report from China. (21132550)	Zou Y.Q.... Ying Z.H.	2012
15	Interstitial lung disease associated with azacitidine use: a case report. (20634671)	Sekhri A.... Selvaraj D.R.	2012
16	Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy. (22282550)	Keir G.J.... Renzoni E.A.	2012
17	Rescue therapy with a pumpless extracorporeal lung assist device in a patient with acute interstitial lung disease and severe refractory hypercapnia. (21762563)	Petzoldt M.... Kluge S.	2012
18	Patterns of interstitial lung disease during everolimus treatment in patients with metastatic renal cell carcinoma. (22438405)	Mizuno R.... Oya M.	2012
19	Disappearance of anti-MDA-5 autoantibodies in clinically amyopathic DM/interstitial lung disease during disease remission. (22210662)	Muro Y.... Akiyama M.	2012
20	A systematic review of validated methods for identifying pulmonary fibrosis and interstitial lung disease using administrative and claims data. (22262614)	Jones N.... Reynolds M.W.	2012
21	Interstitial lung disease outcomes by high-resolution computed tomography (HRCT) in Anti-Jo1 antibody-positive polymyositis patients: a single centre study and review of the literature. (21985773)	Ingegnoli F.... Meroni P.L.	2012
22	Texture feature ranking with relevance learning to classify interstitial lung disease patterns. (23010586)	Huber M.B.... WismA1ller A.	2012
23	Fatal asymmetric interstitial lung disease after erlotinib for lung cancer. (22889962)	Ren S.... Zhang D.	2012
24	Efficacy of blood-patch pleurodesis for secondary spontaneous pneumothorax in interstitial lung disease. (21628929)	Aihara K.... Mishima M.	2011
25	Overlaps in interstitial lung disease--worth a second glance. (21401701)	Nicholson A.G.	2011
26	Airway and interstitial lung disease are distinct entities in paediatric common variable immunodeficiency. (21635229)	van de Ven A.A.... van Montfrans J.M.	2011
27	Prediction of acute pulmonary complications after resection of lung cancer in patients with preexisting interstitial lung disease. (21480134)	Park J.S.... Choi Y.S.	2011
28	Predicting treatment outcomes and responder subsets in scleroderma-related interstitial lung disease. (21547897)	Roth M.D.... Elashoff R.M.	2011
29	Successful erlotinib rechallenge after erlotinib-induced interstitial lung disease. (21623280)	Dallas J.L.... Kaye F.J.	2011
30	Quantitative computed tomographic indexes in diffuse interstitial lung disease: correlation with physiologic tests and computed tomography visual scores. (21412102)	Shin K.E.... Lee K.S.	2011
31	Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis. (20506355)	Seibold J.R.... Black C.M.	2010
32	Aspects of interstitial lung disease review series. (20478853)	McDonald C.	2010
33	N-acetylcysteine inhibits IL-8 and MMP-9 release and ICAM-1 expression by bronchoalveolar cells from interstitial lung disease patients. (20360623)	Radomska-LeA9niewska D.M.... Malejczyk J.	2010
34	Connective tissue disease-associated interstitial lung disease: a call for clarification. (20682528)	Fischer A.... du Bois R.M.	2010
35	Rheumatoid arthritis and interstitial lung disease. (20223815)	Brusselle G.	2010
36	Essential role of osteopontin in smoking-related interstitial lung diseases. (19359522)	Prasse A.... Renkl A.C.	2009
37	Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients. (19615053)	Schmidt K.... Riemekasten G.	2009
38	Adult clinically amyopathic dermatomyositis with rapid progressive interstitial lung disease: a retrospective cohort study. (17308858)	Ye S.... Chen S.L.	2007
39	In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype. (16507114)	Chinoy H.... Cooper R.G.	2006
40	A case of interstitial lung disease with atorvastatin (Tahor) and a review of the literature about these effects observed under statins]. (16792155)	Veyrac G.... Jolliet P.	2006
41	Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD). (15716315)	Bodolay E.... Szegedi G.	2005
42	Interstitial lung disease in polymyositis and dermatomyositis. (16224246)	Fathi M.... Lundberg I.E.	2005
43	Serial chest CT findings in interstitial lung disease associated with polymyositis-dermatomyositis. (14962653)	Bonnefoy O.... Laurent F.	2004
44	Interstitial lung disease in polymyositis and dermatomyositis: clinical course and response to treatment. (12701038)	Schnabel A.... Gross W.L.	2003
45	Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. (16088687)	Elkin S.L.... du Bois R.M.	2001
46	Human bronchoalveolar lavage fluid protein two-dimensional database: study of interstitial lung diseases. (10949149)	Wattiez R.... Falmagne P.	2000
47	Increased incidence of autoantibodies to interleukin-1a in rheumatoid arthritis with interstitial lung disease. (11192540)	Maniwa K.... Sone S.	2000
48	CYFRA 21-1, a cytokeratin subunit 19 fragment, in bronchoalveolar lavage fluid from patients with interstitial lung disease. (9682677)	Kanazawa H.... Yoshikawa J.	1998
49	High resolution CT in respiratory bronchiolitis-associated interstitial lung disease. (8419438)	Holt R.M.... Raghu G.	1993
50	Mast cells, atypical lymphocytes, and neutrophils in bronchoalveolar lavage in extrinsic allergic alveolitis. Comparison with other interstitial lung diseases. (2432812)	Haslam P.L.... Turner-Warwick M.	1987

Genes related to Interstitial Lung Disease

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
See all sources

Genes related to Interstitial Lung Disease:

(show top 50) (show all 131)

id	Symbol	Description	Score	Implication
1	SFTPC	surfactant protein C	20.09	GeneCards inferred : Publications, Disorders, Summaries (show sections)
2	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	19.92	GeneCards inferred : Disorders (show sections)
3	SFTPD	surfactant protein D	19.77	GeneCards inferred : Publications, Disorders (show sections)
4	SFTPB	surfactant protein B	19.61	GeneCards inferred : Publications, Disorders (show sections)
5	SCGB3A2	secretoglobin, family 3A, member 2	19.46	GeneCards inferred : Publications, Disorders (show sections)
6	CHIT1	chitinase 1 (chitotriosidase)	19.31	GeneCards inferred : Publications, Disorders (show sections)
7	CXCL5	chemokine (C-X-C motif) ligand 5	19.16	GeneCards inferred : Publications, Disorders (show sections)
8	CD27	CD27 molecule	19.00	GeneCards inferred : Publications, Disorders (show sections)
9	CCL22	chemokine (C-C motif) ligand 22	18.85	GeneCards inferred : Publications, Disorders (show sections)
10	TAC3	tachykinin 3	18.70	GeneCards inferred : Publications, Disorders (show sections)
11	DUSP23	dual specificity phosphatase 23	18.55	GeneCards inferred : Publications, Disorders (show sections)
12	ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	18.39	GeneCards inferred : Publications, Disorders (show sections)
13	HADHAP1	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1	18.24	GeneCards inferred : Publications, Disorders (show sections)
14	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	18.09	GeneCards inferred : Publications, Disorders (show sections)
15	IL27	interleukin 27	17.93	GeneCards inferred : Publications, Disorders (show sections)
16	CXCL9	chemokine (C-X-C motif) ligand 9	17.78	GeneCards inferred : Publications, Disorders (show sections)
17	STK16	serine/threonine kinase 16	17.63	GeneCards inferred : Publications, Disorders (show sections)
18	GLRX2	glutaredoxin 2	17.48	GeneCards inferred : Publications, Disorders (show sections)
19	CD70	CD70 molecule	17.32	GeneCards inferred : Publications, Disorders (show sections)
20	S100A9	S100 calcium binding protein A9	17.17	GeneCards inferred : Publications, Disorders (show sections)
21	NARS	asparaginyl-tRNA synthetase	17.02	GeneCards inferred : Publications, Disorders (show sections)
22	GLRX	glutaredoxin (thioltransferase)	16.87	GeneCards inferred : Publications, Disorders (show sections)
23	CCR4	chemokine (C-C motif) receptor 4	16.71	GeneCards inferred : Publications, Disorders (show sections)
24	FOSL1	FOS-like antigen 1	16.56	GeneCards inferred : Publications, Disorders (show sections)
25	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	16.41	GeneCards inferred : Publications, Disorders (show sections)
26	CCL17	chemokine (C-C motif) ligand 17	16.26	GeneCards inferred : Publications, Disorders (show sections)
27	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	16.10	GeneCards inferred : Publications, Disorders (show sections)
28	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	15.95	GeneCards inferred : Publications, Disorders (show sections)
29	IL33	interleukin 33	15.80	GeneCards inferred : Publications, Disorders (show sections)
30	TMSB10	thymosin beta 10	15.64	GeneCards inferred : Publications, Disorders (show sections)
31	IFIH1	interferon induced with helicase C domain 1	15.49	GeneCards inferred : Publications, Disorders (show sections)
32	THPO	thrombopoietin	15.34	GeneCards inferred : Publications, Disorders (show sections)
33	ABCA3	ATP-binding cassette, sub-family A (ABC1), member 3	15.19	GeneCards inferred : Publications, Disorders (show sections)
34	CHKB	choline kinase beta	15.03	GeneCards inferred : Publications, Disorders (show sections)
35	CCL5	chemokine (C-C motif) ligand 5	14.88	GeneCards inferred : Publications, Disorders (show sections)
36	CCL3	chemokine (C-C motif) ligand 3	14.73	GeneCards inferred : Publications, Disorders (show sections)
37	PAOX	polyamine oxidase (exo-N4-amino)	14.58	GeneCards inferred : Disorders (show sections)
38	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	14.42	GeneCards inferred : Publications, Disorders (show sections)
39	PROC	protein C (inactivator of coagulation factors Va and VIIIa)	14.27	GeneCards inferred : Publications, Disorders (show sections)
40	SHH	sonic hedgehog	14.12	GeneCards inferred : Publications, Disorders (show sections)
41	COMP	cartilage oligomeric matrix protein	13.97	GeneCards inferred : Publications, Disorders (show sections)
42	CTSH	cathepsin H	13.81	GeneCards inferred : Publications, Disorders (show sections)
43	CCR2	chemokine (C-C motif) receptor 2	13.66	GeneCards inferred : Publications, Disorders (show sections)
44	CXCR3	chemokine (C-X-C motif) receptor 3	13.51	GeneCards inferred : Publications, Disorders (show sections)
45	TSPO	translocator protein (18kDa)	13.35	GeneCards inferred : Publications, Disorders (show sections)
46	CXCL10	chemokine (C-X-C motif) ligand 10	13.20	GeneCards inferred : Publications, Disorders (show sections)
47	TAC1	tachykinin, precursor 1	13.05	GeneCards inferred : Publications, Disorders (show sections)
48	LBR	lamin B receptor	12.90	GeneCards inferred : Publications, Disorders (show sections)
49	CCL4	chemokine (C-C motif) ligand 4	12.74	GeneCards inferred : Publications, Disorders (show sections)
50	HABP2	hyaluronan binding protein 2	12.59	GeneCards inferred : Publications, Disorders (show sections)

Products for genes related to Interstitial Lung Disease disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	49	49	49
2	LSBio	-	-	50

Genetic Variations for Interstitial Lung Disease

Expression for genes affiliated with Interstitial Lung Disease

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Interstitial Lung Disease

Search GEO for disease gene expression data for Interstitial Lung Disease.

Pathways for genes affiliated with Interstitial Lung Disease

Sources:
⁵¹QIAGEN, ²⁹KEGG, ⁵³Reactome
See all sources

Pathways related to Interstitial Lung Disease according to GeneCards/GeneDecks:

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	PEDF Induced Signaling⁵¹ Hide members all-trans-Retinoic Acid Signaling in Brain⁵¹ Cytokine-cytokine receptor interaction²⁹ STAT3 Pathway⁵¹ RAR-Gamma-RXR-Alpha Degradation⁵¹ IL-6 Pathway⁵¹ Endothelin-1 Signaling Pathway⁵¹ MIF Regulation of Innate Immune Cells⁵¹ MIF Mediated Glucocorticoid Regulation⁵¹ NFAT Signaling and Lymphocyte Interactions⁵¹ PGC1Alpha Pathway⁵¹ Glucocorticoid Receptor Signaling⁵¹	10.6	CXCL9, CXCL5, CD27, CD70, CCL18, CCL22
2	Akt Signaling⁵¹ Hide members p38 Signaling⁵¹ Tec Kinases Signaling⁵¹	10.6	CCL18, ITGA3, CXCL5, CXCL9, CCL22
3	Integrin Pathway⁵¹ Hide members Transendothelial Migration of Leukocytes⁵¹ FAK1 Signaling⁵¹ GnRH Signaling⁵¹ UPA-UPAR Pathway⁵¹	10.6	CXCL9, CXCL5, ITGA3, CCL18, CCL22
4	PAK Pathway⁵¹ Hide members Antioxidant Action of Vitamin-C⁵¹	10.6	CCL22, CCL18, GLRX2, CXCL5, CXCL9
5	Chemokine Signaling⁵¹ Hide members Chemokine signaling pathway²⁹	10.5	CCL22, CCL18, CXCL5, CXCL9
6	Chemokine receptors bind chemokines⁵³	10.5	CCL22, CXCL5, CXCL9

Compounds for genes affiliated with Interstitial Lung Disease

Sources:
⁴⁴Novoseek, ⁴⁹PharmGKB, ¹¹DrugBank, ²⁴HMDB, ²⁸IUPHAR
See all sources

Compounds related to Interstitial Lung Disease according to GeneCards/GeneDecks:

(show all 23)

id	Compound	Score	Top Affiliating Genes
1	calcium⁴⁴ ⁴⁹ ¹¹ ²⁴	14.0	CCL22, CCL18, SFTPC, SFTPD, SFTPB, S100A9
2	dexamethasone⁴⁴ ⁴⁹ ²⁸ ¹¹	14.0	CXCL9, CCL22, CCL18, SFTPC, SFTPD, SFTPB
3	tarc⁴⁴	10.9	CCL22, CCL18, CXCL5, CXCL9
4	ccl3⁴⁴ ²⁸	11.9	CXCL9, CXCL5, CCL18, CCL22
5	ccl4⁴⁴ ²⁸	11.9	CCL22, CCL18, CXCL5, CXCL9
6	fibrinogen⁴⁴	10.9	CCL22, SFTPC, SFTPB, S100A9, CHIT1
7	infasurf⁴⁴	10.8	SFTPB, SFTPC
8	rantes⁴⁴	10.8	CXCL5
9	dppg⁴⁴	10.8	SFTPC, SFTPB
10	popg⁴⁴	10.8	SFTPC, SFTPB
11	1,2-dipalmitoyl-sn-glycero-3-phosphocholine⁴⁴	10.8	SFTPC, SFTPB
12	ena 78⁴⁴	10.8	CXCL5, CXCL9
13	curosurf⁴⁴	10.8	SFTPC, SFTPB
14	nitric oxide⁴⁴ ¹¹ ²⁴	12.7	SFTPD, SFTPB, S100A9, CXCL5, CXCL9, TAC3
15	endotoxin⁴⁴	10.7	CXCL5, S100A9
16	dopc⁴⁴	10.7	SFTPC, SFTPB
17	survanta⁴⁴	10.7	SFTPC, SFTPB
18	dppc⁴⁴	10.6	SFTPB, SFTPC
19	butanol⁴⁴	10.6	SFTPC, SFTPB
20	vegf⁴⁴	10.6	CXCL9, CXCL5, SFTPB, SFTPC, CCL18
21	p-opc⁴⁴	10.5	SFTPC, SFTPB
22	chloroform⁴⁴	10.4	SFTPC, SFTPB
23	larc⁴⁴	10.2	CCL18, CCL22

GO Terms for genes affiliated with Interstitial Lung Disease

Sources:
¹⁶Gene Ontology
See all sources

Cellular components related to Interstitial Lung Disease according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:005576	10.6	SFTPD, S100A9, SCGB3A2, CD27, CXCL5, CXCL9
2	extracellular space	GO:005615	10.4	TAC3, CCL22, CCL18, SFTPC, SFTPD, SFTPB

Biological processes related to Interstitial Lung Disease according to GeneCards/GeneDecks:

(show all 7)

id	Name	GO ID	Score	Top Affiliating Genes
1	cell-cell signaling	GO:007267	10.7	CXCL9, CXCL5, CD70, S100A9, CCL18, CCL22
2	immune response	GO:006955	10.7	CCL22, CCL18, CHIT1, CD70, CXCL5, CXCL9
3	chemotaxis	GO:006935	10.6	CXCL9, CXCL5, CCL18, CCL22
4	inflammatory response	GO:006954	10.6	CCL22, CCL18, S100A9, CXCL9, IL27
5	response to bacterium	GO:009617	10.5	IL27, CHIT1
6	respiratory gaseous exchange	GO:007585	10.4	SFTPB, SFTPD, SFTPC
7	signal transduction	GO:007165	10.3	CCL22, CCL18, S100A9, CD70, CXCL5, CXCL9