MCID: INT067
MIFTS: 51

Interstitial Nephritis

Categories: Nephrological diseases

Aliases & Classifications for Interstitial Nephritis

MalaCards integrated aliases for Interstitial Nephritis:

Name: Interstitial Nephritis 12 14
Nephritis, Interstitial 41 69
Renal Tubulo-Interstitial Disease 12
Nephritis, Tubulointerstitial 69
Tubulointerstitial Nephritis 28
Nephritis Interstitial 51

Classifications:



External Ids:

Disease Ontology 12 DOID:1063
MeSH 41 D009395
NCIt 46 C26834
SNOMED-CT 64 264536006 28689008

Summaries for Interstitial Nephritis

MalaCards based summary : Interstitial Nephritis, also known as nephritis, interstitial, is related to hypoaldosteronism and nephronophthisis 16. An important gene associated with Interstitial Nephritis is FAN1 (FANCD2 And FANCI Associated Nuclease 1), and among its related pathways/superpathways are Peptide hormone metabolism and ACE Inhibitor Pathway, Pharmacodynamics. The drugs Cefixime and Ceftriaxone have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and t cells, and related phenotypes are homeostasis/metabolism and liver/biliary system

Wikipedia : 72 Interstitial nephritis (or tubulo-interstitial nephritis) is a form of nephritis affecting the... more...

Related Diseases for Interstitial Nephritis

Diseases related to Interstitial Nephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 254)
# Related Disease Score Top Affiliating Genes
1 hypoaldosteronism 32.2 ACE REN
2 nephronophthisis 16 32.1 ANKS6 INVS MAPKBP1
3 pyelitis 31.2 CRP REN
4 pyelonephritis 30.7 ACE ALB CRP UMOD
5 acute kidney tubular necrosis 30.0 ALB UMOD
6 membranous nephropathy 30.0 ACE ALB TINAG
7 microvascular complications of diabetes 3 29.9 ACE AGT ALB
8 renal tuberculosis 29.8 CRP REN
9 granulomatous hepatitis 29.7 ACE CRP
10 kidney disease 29.5 ACE ALB REN UMOD
11 hyperuricemia 29.3 CRP REN UMOD
12 nephronophthisis 29.3 ANKS6 INVS MAPKBP1 UMOD
13 chronic kidney failure 28.3 ACE AGT ALB CRP INVS REN
14 end stage renal failure 28.3 ACE AGT ALB ANKS6 CRP UMOD
15 interstitial nephritis, karyomegalic 12.7
16 megalocytic interstitial nephritis 12.5
17 danubian endemic familial nephropathy 11.3
18 nephronophthisis 2 11.0
19 nephronophthisis 15 11.0
20 nephronophthisis 20 11.0
21 autosomal dominant tubulointerstitial kidney disease 11.0
22 chronic pyelonephritis 10.8
23 acute pyelonephritis 10.6
24 hyporeninemic hypoaldosteronism 10.5 ACE REN
25 renal artery obstruction 10.4 ACE REN
26 hypertension, diastolic 10.4 ACE REN
27 atrial septal defect 4 10.4 ACE REN
28 hypertensive retinopathy 10.4 ACE REN
29 benign essential hypertension 10.4 ALB REN
30 renal artery disease 10.4 ACE REN
31 hypertensive nephropathy 10.4 ACE ALB
32 syndrome of inappropriate antidiuretic hormone 10.4 ACE ALB
33 kidney papillary necrosis 10.4 ALB REN
34 generalized atherosclerosis 10.4 ACE CRP
35 malignant essential hypertension 10.4 ACE REN
36 pediatric hypertension 10.4 ACE AGT
37 angina pectoris 10.3 ACE CRP
38 pyuria 10.3 ALB CRP
39 decubitus ulcer 10.3 ALB CRP
40 subdural empyema 10.3 ACE CRP
41 posterior urethral valves 10.3 ACE AGT
42 tuberculous peritonitis 10.3 ALB CRP
43 hypersensitivity reaction type iii disease 10.3 ALB CRP
44 uveitis 10.3
45 chronic conjunctivitis 10.3
46 igg4-related kidney disease 10.3
47 aortic coarctation 10.3 ACE AGT
48 ischemic heart disease 10.3 ACE CRP
49 diastolic heart failure 10.3 ACE AGT
50 systolic heart failure 10.3 ACE CRP

Graphical network of the top 20 diseases related to Interstitial Nephritis:



Diseases related to Interstitial Nephritis

Symptoms & Phenotypes for Interstitial Nephritis

MGI Mouse Phenotypes related to Interstitial Nephritis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.9 ACE AGT ALB APRT CRP FAN1
2 liver/biliary system MP:0005370 9.43 ACE AGT ALB ANKS6 FAN1 INVS
3 renal/urinary system MP:0005367 9.23 ACE AGT ALB APRT FAN1 INVS

Drugs & Therapeutics for Interstitial Nephritis

Drugs for Interstitial Nephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 150)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefixime Approved, Investigational Phase 4 79350-37-1 5362065 54362
2
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
3
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 85721-33-1 2764
4
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3 67-20-9 5353830
5
Sulfamethoxazole Approved Phase 4,Phase 3 723-46-6 5329
6
Trimethoprim Approved, Vet_approved Phase 4,Phase 3 738-70-5 5578
7
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 100986-85-4 149096
8
Ofloxacin Approved Phase 4,Phase 3,Phase 2 82419-36-1 4583
9
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
10
Cephalexin Approved, Investigational, Vet_approved Phase 4 15686-71-2 27447
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
12
leucovorin Approved, Nutraceutical Phase 4,Phase 3 58-05-9 143 6006
13 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
14 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
15 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
16 Antitubercular Agents Phase 4,Phase 3,Not Applicable
17 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2
18 Fluoroquinolones Phase 4,Phase 2
19 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
20 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3,Phase 2
21 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
22 Antimalarials Phase 4,Phase 3
23 Antiparasitic Agents Phase 4,Phase 3
24 Antiprotozoal Agents Phase 4,Phase 3
25 Folic Acid Antagonists Phase 4,Phase 3
26 Renal Agents Phase 4,Phase 3,Phase 2
27 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4,Phase 3
28 Vitamin B Complex Phase 4,Phase 3
29 Amdinocillin Pivoxil Phase 4
30 Folate Nutraceutical Phase 4,Phase 3
31 Vitamin B9 Nutraceutical Phase 4,Phase 3
32
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
33
Fosfomycin Approved Phase 2, Phase 3 23155-02-4 446987
34
Piperacillin Approved Phase 2, Phase 3 66258-76-2 43672
35
Tazobactam Approved Phase 2, Phase 3 89786-04-9 123630
36
Meropenem Approved, Investigational Phase 3,Phase 2 119478-56-7 441130 64778
37 Avibactam Approved Phase 3 1192500-31-4
38
Ceftazidime Approved Phase 3,Phase 2 72558-82-8, 78439-06-2 5481173
39
Colistin Approved Phase 3 1066-17-7, 1264-72-8 5311054
40
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
41
Tigecycline Approved Phase 3 220620-09-7 5282044
42
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
43
Asparaginase Approved, Investigational Phase 3 9015-68-3
44
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
45
Cytarabine Approved, Investigational Phase 3 147-94-4 6253
46
Daunorubicin Approved Phase 3 20830-81-3 30323
47
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
48
Etoposide Approved Phase 3 33419-42-0 36462
49
Fludarabine Approved Phase 3 21679-14-1, 75607-67-9 30751
50
Ifosfamide Approved Phase 3 3778-73-2 3690

Interventional clinical trials:

(show top 50) (show all 69)

# Name Status NCT ID Phase Drugs
1 Efficacy and Safety Study of Short-term Antibiotic for Pyelonephritis in Women Completed NCT01390623 Phase 4 Ceftriaxone
2 Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old Completed NCT00136656 Phase 4 antibiotic;antibiotics
3 Pharmacokinetics of Ciprofloxacin in Pediatric Patients Completed NCT02598362 Phase 4 ciprofloxacin
4 A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux Completed NCT00382343 Phase 4 Sulfamethoxazole/trimethoprim
5 Treatment's Duration of Acute Uncomplicated Pyelonephritis Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
6 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
7 Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community Pyelonephritis Recruiting NCT03179384 Phase 4 Ceftriaxone
8 Treating Pyelonephritis an Urosepsis With Pivmecillinam Recruiting NCT03282006 Phase 4 pivmecillinam
9 Management of Sub-Clinical Bacteriuria in Pregnancy Not yet recruiting NCT03275623 Phase 4 Antibiotic
10 Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course Levofloxacin Terminated NCT00239161 Phase 4 Levofloxacin
11 ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study Unknown status NCT02155803 Phase 2, Phase 3 ACTHAR Gel (adrenocorticotropic hormone)
12 Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in Children Unknown status NCT02192580 Phase 3 Omega-3
13 L-carnitine on the Prevention of Renal Scarring in Acute Pyelonephritis Unknown status NCT02007889 Phase 3 L-carnitine
14 Contrast-Enhanced US of Spleen, Liver and Kidney Unknown status NCT00190281 Phase 3
15 CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria Completed NCT03477422 Phase 3 CSE-1034 (Ceftriaxone + Sulbactam + EDTA);Meropenem
16 Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections Completed NCT02753946 Phase 2, Phase 3 ZTI-01;Piperacillin-tazobactam
17 Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) Completed NCT02728089 Phase 3 MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)
18 A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) Completed NCT02486627 Phase 3 plazomicin;meropenem;levofloxacin (oral)
19 Efficacy, Safety, Tolerability of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Complicated Urinary Tract Infections (cUTIs), Including Acute Pyelonephritis (AP), in Adults Completed NCT02166476 Phase 3 Meropenem-Vaborbactam;Piperacillin-Tazobactam;Levofloxacin;Saline
20 Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Completed NCT01599806 Phase 3 Ceftazidime - Avibactam ( CAZ-AVI);Doripenem;Either switch to oral therapy: 500 mg of Ciprofloxacin (oral);or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)
21 Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Completed NCT01595438 Phase 3 Ceftazidime - Avibactam ( CAZ-AVI);Doripenem;Either switch to oral therapy: 500 mg of Ciprofloxacin (oral);or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)
22 Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis Completed NCT01345929 Phase 3 CXA-201;Levofloxacin
23 Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis Completed NCT00229021 Phase 3 doripenum
24 Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis Completed NCT00210990 Phase 3 doripenem
25 A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis. Completed NCT00210886 Phase 3 levofloxacin
26 A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections Completed NCT00258089 Phase 3 Levofloxacin
27 A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) Completed NCT01970371 Phase 3 plazomicin;colistin;meropenem;tigecycline;antibiotic of Investigator's choice
28 Efficacy, Safety, Tolerability of Carbavance Compared to Best Available Therapy in Serious Infections Due to Carbapenem Resistant Enterobacteriaceae, in Adults Completed NCT02168946 Phase 3 Carbavance;Best Available Therapy
29 International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia Active, not recruiting NCT01117441 Phase 3 PEG-L-asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;mercaptopurine;methotrexate;prednisone;thioguanine;vincristine sulfate;vindesine;daunoxome;fludarabine
30 Short-term Antibiotic Therapy for Pyelonephritis in Childhood Terminated NCT00724256 Phase 3 ceftibuten;ceftibuten
31 A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections Terminated NCT01110408 Phase 3 Doripenem;Doripenem placebo;Cefepime;Cefepime placebo;Amoxicillin/clavulanate potassium
32 Antibiotic Prophylaxis in Children With Pyelonephritis Withdrawn NCT00752375 Phase 3 Trimethoprim Sulfamethoxazole;placebo
33 Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli Unknown status NCT02537847 Phase 2 Sitafloxacin;Ertapenem
34 Rituximab in IgG4-RD: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2 Rituximab
35 Effect of Acetylcysteine in Pediatric Acute Pyelonephritis. Completed NCT02080182 Phase 2 Acetylcysteine;placebo acetylcysteine
36 A Study of Efficacy/Safety of Intravenous S-649266 Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections Completed NCT02321800 Phase 2 S-649266;Imipenem/cilastatin
37 Study of the Safety, Tolerability, and Efficacy of MK-7655 + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for the Treatment of Complicated Urinary Tract Infection (cUTI) (MK-7655-003) Completed NCT01505634 Phase 2 MK-7655 250 mg;MK-7655 125 mg;imipenem/cilastatin 500 mg;Placebo to MK-7655;Ciprofloxacin
38 Study of Plazomicin (ACHN-490) Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis Completed NCT01096849 Phase 2 levofloxacin;plazomicin;placebo
39 Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections Completed NCT00921024 Phase 2 CXA-101;Ceftazidime
40 Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis Completed NCT01928433 Phase 2 Finafloxacin 800 mg i.v. once daily;Finafloxacin placebo i.v. once daily;Finafloxacin 800 mg tablets once daily;Finafloxacin placebo tablets once daily;Ciprofloxacin 400 mg i.v. twice daily;Ciprofloxacin placebo i.v. twice daily;Ciprofloxacin 500 mg oral twice daily;Ciprofloxacin placebo oral twice daily
41 Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN) Recruiting NCT01893658 Phase 2 Omalizumab;Prednisone
42 Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections Recruiting NCT03445195 Phase 2 Sulbactam-ETX2514;Placebo;Imipenem-cilastatin
43 MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) Recruiting NCT03230838 Phase 2 Ceftolozane;Tazobactam;Meropenem
44 GSK2251052 in Complicated Urinary Tract Infection Terminated NCT01381549 Phase 2 GSK2251052;imipenem-cilastatin
45 Prospective Study in the Emergency Terminated NCT01628900 Phase 2
46 Anti-BK Virus Immune Response and Kidney Transplantation Unknown status NCT01109186
47 Evaluation of a Predictive Immunovirological Test Occurrence of BK Virus Nephropathy in Renal Transplant Unknown status NCT02049827
48 Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection Unknown status NCT02034851
49 Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria Unknown status NCT01771432 Not Applicable Antibiotic treatment
50 Proteinuria During Acute Pyelonephritis In Pregnancy Unknown status NCT02536638 Not Applicable

Search NIH Clinical Center for Interstitial Nephritis

Cochrane evidence based reviews: nephritis, interstitial

Genetic Tests for Interstitial Nephritis

Genetic tests related to Interstitial Nephritis:

# Genetic test Affiliating Genes
1 Tubulointerstitial Nephritis 28

Anatomical Context for Interstitial Nephritis

MalaCards organs/tissues related to Interstitial Nephritis:

38
Kidney, Bone, T Cells, Thyroid, Liver, Testes, Neutrophil

Publications for Interstitial Nephritis

Articles related to Interstitial Nephritis:

(show top 50) (show all 660)
# Title Authors Year
1
Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: clues to an epidemic of chronic interstitial nephritis of agricultural communities. ( 29437864 )
2018
2
Clinical Manifestations and Outcomes of Fluoroquinolone-Related Acute Interstitial Nephritis. ( 29157532 )
2018
3
Granulomatous interstitial nephritis associated with silica. ( 29346841 )
2018
4
Interstitial Nephritis Secondary to Vedolizumab Treatment in Crohn Disease and Safe Rechallenge Using Steroids: A Case Report. ( 29162338 )
2018
5
Membranoproliferative glomerulonephritis and interstitial nephritis in the setting of Epstein-Barr virus-related hemophagocytic syndromea8c. ( 29350173 )
2018
6
Successful use of rituximab in glomerular basement membrane nephritis associated withA HIV interstitial nephritis secondary to Castleman diseasea8c. ( 29424337 )
2018
7
Proton Pump Inhibitor and H2 Blocker-Associated Acute Interstitial Nephritis in a Renal Allograft. ( 29023281 )
2017
8
Urine Eosinophils for Acute Interstitial Nephritis. ( 28459905 )
2017
9
Acute interstitial nephritis after sequential ipilumumab - nivolumab therapy of metastatic melanoma. ( 28716106 )
2017
10
Cyclooxygenase-2 inhibitor-induced acute interstitial nephritis. ( 28536229 )
2017
11
Monoclonal gammopathy of renal significance presenting as monotypic plasma cell interstitial nephritis in two patients with SjAPgren's syndrome. ( 29147924 )
2017
12
Silent Acute Interstitial Nephritis: Suspicion Is the Key to Diagnosis. ( 29203249 )
2017
13
Case 6: Skin Discoloration, Methemoglobinemia, and Acute Interstitial Nephritis in a 15-year-old Girl. ( 28765205 )
2017
14
A case of acute kidney injury caused by granulomatous interstitial nephritis associated with sarcoidosis. ( 29181823 )
2017
15
Acute Interstitial Nephritis Associated with Sofosbuvir and Daclatasvir. ( 28706960 )
2017
16
Undiagnosed renal sarcoidosis in a patient with chronic interstitial nephritis. ( 28875342 )
2017
17
Combination Cyclophosphamide/Glucocorticoids Provide Better Tolerability and Outcomes versus Glucocorticoids Alone in Patients with Sjogren's Associated Chronic Interstitial Nephritis. ( 29241210 )
2017
18
Acute Ciprofloxacin-Induced Crystal Nephropathy with Granulomatous Interstitial Nephritis. ( 28553048 )
2017
19
Acute interstitial nephritis in the south of Iran; an observational study. ( 28975105 )
2017
20
Alendronate sodium-induced interstitial nephritis. ( 29105273 )
2017
21
Infection associated acute interstitial nephritis; a case report. ( 28491853 )
2017
22
Novel oral anticoagulant and kidney injury: apixaban-related acute interstitial nephritis. ( 28847995 )
2017
23
Clinical profile and outcome of patients with biopsy-proven acute interstitial nephritis in Cape Town: a 10-year reviewa8c. ( 28438256 )
2017
24
Severe Acute Interstitial Nephritis: Response to Therapy With AntithymocyteA Globulin. ( 29142951 )
2017
25
The increasing rates of acute interstitial nephritis in Australia: a single centre case series. ( 29089041 )
2017
26
Acute kidney injury with granulomatous interstitial nephritis and vasculitis revealing sarcoidosis. ( 28937078 )
2017
27
Acute granulomatous interstitial nephritis and acute rejection in a kidney transplant recipient after zoledronic acid therapy - a case report and review of the literature. ( 28655390 )
2017
28
Sunitinib-Induced Acute Interstitial Nephritis in a Thrombocytopenic Renal Cell Cancer Patient. ( 29359059 )
2017
29
A Case Report of Acute Renal Failure as a Result of Light-Chain-Mediated Acute Tubular Interstitial Nephritis in a 30-Year-Old Combat Veteran. ( 29087890 )
2017
30
AJKD Atlas of Renal Pathology: Chronic Interstitial Nephritis. ( 28646984 )
2017
31
Granulomatous interstitial nephritis due to chronic lymphocytic leukemia: a case report. ( 29197349 )
2017
32
IgG4-Related Disease Manifesting as Interstitial Nephritis Accompanied by Hypophysitis. ( 28552902 )
2017
33
Acute Interstitial Nephritis Induced by Citrullus Colocynthis. ( 29038395 )
2017
34
Drug-Induced Acute Interstitial Nephritis. ( 28893923 )
2017
35
A case report of zinc phosphide poisoning: complicated by acute renal failure and tubulo interstitial nephritis. ( 28545504 )
2017
36
Acute interstitial nephritis and DRESS syndrome without eosinophilia associated with cefepime. ( 28775112 )
2017
37
Allergic Interstitial Nephritis Masquerading as Pyelonephritis in a Pediatric Patient With Crohn Disease. ( 28644363 )
2017
38
Drug-Induced Acute Interstitial Nephritis with Nifedipine. ( 26955492 )
2016
39
Granulomatous interstitial nephritis and Crohn's disease. ( 27478596 )
2016
40
Piperacillin-Tazobactam Induced Interstitial Nephritis, Hepatitis and Serum Sckness-Like Illness. ( 27434982 )
2016
41
Acute interstitial nephritis, toxic hepatitis and toxic myocarditis following multiple Asian giant hornet stings in Shaanxi Province, China. ( 26910407 )
2016
42
Regression of a Pulmonary Arteriovenous Malformation after Acute Interstitial Nephritis. ( 27250058 )
2016
43
Erratum: Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma. ( 27478613 )
2016
44
Acute interstitial nephritis in T-cell leukemia in a pediatric patient. ( 27594450 )
2016
45
The use of gallium-67 scintigraphy in the diagnosis of acute interstitial nephritis. ( 26798465 )
2016
46
Acute interstitial nephritis with membranous nephropathy in bucillamine-treated rheumatoid arthritis. ( 28509179 )
2016
47
Interstitial nephritis caused by HIV infection by itself: a case report. ( 27621665 )
2016
48
Acute interstitial nephritis caused by two different proton pump inhibitors. ( 26903459 )
2016
49
COXPD9 an Evolving Multisystem Disease; Congenital Lactic Acidosis, Sensorineural Hearing Loss, Hypertrophic Cardiomyopathy, Cirrhosis and Interstitial Nephritis. ( 27815843 )
2016
50
A rare case of lamotrigine-induced acute interstitial nephritis. ( 27987281 )
2016

Variations for Interstitial Nephritis

Expression for Interstitial Nephritis

Search GEO for disease gene expression data for Interstitial Nephritis.

Pathways for Interstitial Nephritis

GO Terms for Interstitial Nephritis

Cellular components related to Interstitial Nephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.23 ACE AGT ALB APRT CRP REN

Biological processes related to Interstitial Nephritis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.58 ACE AGT REN
2 regulation of blood pressure GO:0008217 9.54 ACE AGT REN
3 positive regulation of protein tyrosine kinase activity GO:0061098 9.51 ACE AGT
4 blood vessel remodeling GO:0001974 9.49 ACE AGT
5 regulation of vasoconstriction GO:0019229 9.48 ACE AGT
6 amyloid-beta metabolic process GO:0050435 9.46 ACE REN
7 positive regulation of superoxide anion generation GO:0032930 9.43 AGT CRP
8 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.32 ACE AGT
9 renin-angiotensin regulation of aldosterone production GO:0002018 9.26 AGT REN
10 regulation of blood volume by renin-angiotensin GO:0002016 9.16 AGT REN
11 regulation of renal output by angiotensin GO:0002019 8.96 ACE AGT
12 angiotensin maturation GO:0002003 8.8 ACE AGT REN

Sources for Interstitial Nephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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