MCID: INT012
MIFTS: 20

Interval Angle-Closure Glaucoma

Categories: Eye diseases

Aliases & Classifications for Interval Angle-Closure Glaucoma

MalaCards integrated aliases for Interval Angle-Closure Glaucoma:

Name: Interval Angle-Closure Glaucoma 12 14
Intermittent Angle-Closure Glaucoma 12 69
Angle-Closure Glaucoma, Subacute 12
Prodromal Angle Closure Glaucoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13549
ICD10 33 H40.23
ICD9CM 35 365.21
SNOMED-CT 64 65460003
UMLS 69 C0154945

Summaries for Interval Angle-Closure Glaucoma

MalaCards based summary : Interval Angle-Closure Glaucoma, also known as intermittent angle-closure glaucoma, is related to optic disk drusen and nemaline myopathy. An important gene associated with Interval Angle-Closure Glaucoma is IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial), and among its related pathways/superpathways are Glucose / Energy Metabolism and Carbon metabolism. Affiliated tissues include eye.

Related Diseases for Interval Angle-Closure Glaucoma

Graphical network of the top 20 diseases related to Interval Angle-Closure Glaucoma:



Diseases related to Interval Angle-Closure Glaucoma

Symptoms & Phenotypes for Interval Angle-Closure Glaucoma

Drugs & Therapeutics for Interval Angle-Closure Glaucoma

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Clinical Study of LPI on Different Sites of Iris Active, not recruiting NCT02870504
2 Clinical Study of LPI With Different Laser Wavelengths Active, not recruiting NCT02901730

Search NIH Clinical Center for Interval Angle-Closure Glaucoma

Genetic Tests for Interval Angle-Closure Glaucoma

Anatomical Context for Interval Angle-Closure Glaucoma

MalaCards organs/tissues related to Interval Angle-Closure Glaucoma:

39
Eye

Publications for Interval Angle-Closure Glaucoma

Variations for Interval Angle-Closure Glaucoma

Expression for Interval Angle-Closure Glaucoma

Search GEO for disease gene expression data for Interval Angle-Closure Glaucoma.

Pathways for Interval Angle-Closure Glaucoma

GO Terms for Interval Angle-Closure Glaucoma

Cellular components related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.62 IDH1 IDH2

Biological processes related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.26 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.16 IDH1 IDH2
3 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
4 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.37 IDH1 IDH2
2 magnesium ion binding GO:0000287 9.32 IDH1 IDH2
3 NAD binding GO:0051287 9.26 IDH1 IDH2
4 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
5 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH1 IDH2
6 isocitrate dehydrogenase activity GO:0004448 8.62 IDH1 IDH2

Sources for Interval Angle-Closure Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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