MCID: INT070
MIFTS: 55

Intestinal Obstruction

Categories: Fetal diseases, Gastrointestinal diseases, Rare diseases, Neuronal diseases

Aliases & Classifications for Intestinal Obstruction

Summaries for Intestinal Obstruction

MedlinePlus : 41 an intestinal obstruction occurs when food or stool cannot move through the intestines. the obstruction can be complete or partial. there are many causes. the most common are adhesions, hernias, cancers, and certain medicines. symptoms include severe abdominal pain or cramping vomiting bloating loud bowel sounds swelling of the abdomen inability to pass gas constipation a complete intestinal obstruction is a medical emergency. it often requires surgery. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Intestinal Obstruction is related to hirschsprung disease 1 and intrahepatic cholangiocarcinoma, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Intestinal Obstruction is GDNF (Glial Cell Derived Neurotrophic Factor), and among its related pathways/superpathways is TCR signaling in naive CD4+ T cells. The drugs Benzocaine and Naloxone have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and kidney, and related phenotypes are behavior/neurological and cellular

Related Diseases for Intestinal Obstruction

Diseases in the Intestinal Obstruction family:

Intestinal Pseudo-Obstruction

Diseases related to Intestinal Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 264)
id Related Disease Score Top Affiliating Genes
1 hirschsprung disease 1 31.8 EDN3 EDNRB GDNF RET
2 intrahepatic cholangiocarcinoma 29.4 CDX2 KRT20 KRT7
3 paralytic ileus 22.5 ACHE CD8A CDX2 CFTR EDN3 EDNRB
4 meconium ileus 11.8
5 peritonitis 11.1
6 visceral myopathy 11.1
7 wandering spleen 11.1
8 megalocytic interstitial nephritis 10.9 GDNF RET
9 intestinal pseudoobstruction, neuronal 10.9
10 wallerian degeneration 10.8 EDN3 EDNRB
11 central hypoventilation syndrome, congenital 10.7 EDNRB GDNF RET
12 gastrointestinal defects and immunodeficiency syndrome 10.7
13 chronic atrial and intestinal dysrhythmia 10.7
14 hirschsprung disease 3 10.7
15 hirschsprung disease 2 10.7
16 hirschsprung disease 4 10.7
17 polyposis, juvenile intestinal 10.7
18 duodenal atresia 10.7
19 diphyllobothriasis 10.7
20 colonic pseudo-obstruction 10.7
21 intestinal pseudo-obstruction 10.7
22 fasciolopsiasis 10.7
23 actg2-related disorders 10.7
24 abdominal cystic lymphangioma 10.7
25 desmoid tumor 10.7
26 hypoganglionosis 10.7
27 diabetes mellitus, noninsulin-dependent, 5 10.7 EDN3 EDNRB RET
28 hypogonadotropic hypogonadism without anosmia, x-linked 10.6 ACHE GDNF RET
29 medullary thyroid carcinoma, familial 10.6 EDNRB GDNF RET
30 intussusception 10.6
31 rhinosporidiosis 10.6 CDX2 KRT20
32 autoinflammation with infantile enterocolitis 10.6 ACHE RET
33 tyrosinemia 10.5 EDN3 EDNRB RET
34 gastric adenocarcinoma 10.5 CDX2 KRT20
35 shprintzen-goldberg syndrome 10.5 EDN3 EDNRB GDNF RET
36 endometrial clear cell adenocarcinoma 10.5 EDNRB NOD2 RET
37 breast mucinous cystadenocarcinoma 10.5 CDX2 KRT20
38 sweat gland cancer 10.5 EDNRB FLNA GDNF RET
39 vestibulocochlear nerve disease 10.5 GDNF HDC RET
40 childhood teratoma of the ovary 10.5 CDX2 KRT20
41 bone giant cell tumor 10.4 KRT20 KRT7
42 intestinal volvulus 10.4
43 periosteal osteogenic sarcoma 10.4 KRT20 KRT7
44 synovitis 10.4 CDX2 KRT7
45 malignant histiocytosis 10.4 FLNA RET
46 steroid-induced glaucoma - borderline 10.4 KRT20 KRT7
47 ludwig's angina 10.4 KRT20 KRT7
48 clear cell squamous cell skin carcinoma 10.4 KRT20 KRT7
49 bile duct mucinous adenocarcinoma 10.4 CDX2 KRT7
50 intracranial chondrosarcoma 10.4 CFTR FLNA

Comorbidity relations with Intestinal Obstruction via Phenotypic Disease Network (PDN): (show top 50) (show all 57)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Anxiety Disorder Ascending Colon Cancer
Bronchitis Candidiasis
Cecal Benign Neoplasm Cervical Cancer, Somatic
Chronic Kidney Failure Chronic Myocardial Ischemia
Chylomicron Retention Disease Colorectal Cancer
Crohn's Disease Decubitus Ulcer
Deficiency Anemia Descending Colon Cancer
Enterovesical Fistula Esophageal Disease
Esophagitis Familial Atrial Fibrillation
Gastrointestinal System Cancer Generalized Atherosclerosis
Heart Disease Hepatic Flexure Cancer
Hydronephrosis Hypertension, Essential
Hypothyroidism Intestinal Disease
Intestinal Perforation Intestinal Volvulus
Iron Deficiency Anemia Irritable Bowel Syndrome
Jejunal Cancer Kidney Disease
Marasmus Mesenteric Artery Ischemia
Neutropenia Osteoporosis
Ovarian Cancer, Somatic Pancreatic Cancer
Pancreatitis, Hereditary Paralytic Ileus
Peritonitis Postgastrectomy Syndrome
Protein-Energy Malnutrition Radiation Cystitis
Rectal Neoplasm Rectosigmoid Junction Neoplasm

Graphical network of the top 20 diseases related to Intestinal Obstruction:



Diseases related to Intestinal Obstruction

Symptoms & Phenotypes for Intestinal Obstruction

UMLS symptoms related to Intestinal Obstruction:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

MGI Mouse Phenotypes related to Intestinal Obstruction:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.31 ACHE CFTR EDN3 EDNRB FLNA GDNF
2 cellular MP:0005384 10.22 CD8A CDX2 EDNRB FLNA GDNF KRT7
3 digestive/alimentary MP:0005381 10.2 CFTR EDN3 EDNRB FLNA GDNF GUCY2C
4 growth/size/body region MP:0005378 10.18 EDNRB FLNA GDNF GUCY2C HDC MTOR
5 endocrine/exocrine gland MP:0005379 10.13 CD8A CDX2 CFTR EDNRB GDNF MTOR
6 homeostasis/metabolism MP:0005376 10.13 ACHE CDX2 CFTR EDNRB FLNA GUCY2C
7 hematopoietic system MP:0005397 10.07 ACHE CD8A CFTR FLNA GDNF HDC
8 immune system MP:0005387 10.03 CD8A CFTR EDNRB FLNA GDNF GUCY2C
9 mortality/aging MP:0010768 10 FLNA GDNF GUCY2C MTOR NOD2 PDPK1
10 muscle MP:0005369 9.5 MTOR NRTN PDPK1 RET ACHE EDNRB
11 nervous system MP:0003631 9.36 ACHE CD8A EDN3 EDNRB FLNA GDNF

Drugs & Therapeutics for Intestinal Obstruction

Drugs for Intestinal Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 282)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
2
Naloxone Approved, Vet_approved Phase 4,Phase 3,Phase 1 465-65-6 5284596
3
Somatostatin Approved Phase 4,Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
4
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3 9004-61-9 53477741 24759
5
Bupivacaine Approved, Investigational Phase 4,Phase 2 2180-92-9, 38396-39-3 2474
6
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
7
Morphine Approved, Investigational Phase 4,Phase 2 57-27-2 5288826
8
Dimenhydrinate Approved Phase 4 523-87-5 441281
9 Simethicone Approved Phase 4
10
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
11
Alvimopan Approved Phase 4,Phase 3 156053-89-3 5488548
12
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
13
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
14
Dalteparin Approved Phase 4 9005-49-6
15
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
16
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
17
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
18
Lidocaine Approved, Vet_approved Phase 4,Phase 2 137-58-6 3676
19
Acetaminophen Approved Phase 4 103-90-2 1983
20
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
21
Guaifenesin Approved, Vet_approved Phase 4 93-14-1 3516
22
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
23
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
24
Methadone Approved Phase 4 76-99-3 4095
25
Orphenadrine Approved Phase 4 83-98-7 4601
26
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
27
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
28 tannic acid Approved, Nutraceutical Phase 4
29 Mosapride Investigational Phase 4 112885-41-3
30 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
31 Hormones Phase 4,Phase 3,Phase 2,Phase 1
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
33 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
35 Analgesics Phase 4,Phase 1
36 Anesthetics Phase 4,Phase 2
37 Anesthetics, Local Phase 4,Phase 2
38 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Central Nervous System Depressants Phase 4,Phase 2,Phase 1
40 Narcotics Phase 4,Phase 3,Phase 2,Phase 1
41 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Dermatologic Agents Phase 4,Phase 3
43 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Neurotransmitter Agents Phase 4,Phase 1,Phase 2
45 Liver Extracts Phase 4,Phase 2,Phase 1
46 Analgesics, Non-Narcotic Phase 4,Phase 1
47 Anesthetics, General Phase 4
48 Anesthetics, Intravenous Phase 4
49 Antirheumatic Agents Phase 4,Phase 3,Phase 1
50 Narcotic Antagonists Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 234)

id Name Status NCT ID Phase Drugs
1 Identifying the Effect of Somatostatin Treatment in Early Postoperative Simple Small Bowel Obstruction Completed NCT01082627 Phase 4 Somatostatin
2 (Gastrografin Use in Small Bowel Obstruction Caused by Adherences) Completed NCT00601809 Phase 4 Gastrografin®: G
3 Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction Completed NCT00389116 Phase 4 gastrograffin;water
4 SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery Completed NCT00531739 Phase 4
5 The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery Completed NCT02773251 Phase 4 hyaluronic acid-carboxymethylcellulose
6 Adult Patients Undergoing Open Colectomy MA402S23B303 Completed NCT01507246 Phase 4 IV morphine sulfate;EXPAREL (bupivacaine liposome injectable suspension)
7 Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy Completed NCT00934999 Phase 4
8 Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery Completed NCT02161367 Phase 4 Simethicone;Oral Suspending Vehicle
9 A New Approach of Neostigmine in Unavoidable Post Operative Ileus Completed NCT00676377 Phase 4 Neostigmine;Saline
10 Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation Completed NCT01956643 Phase 4
11 Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery Completed NCT01440712 Phase 4 Gastrografin;physiological serum
12 A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy Completed NCT00708201 Phase 4 Alvimopan;Placebo
13 Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children Completed NCT01592734 Phase 4 Polyethylene glycol with electrolytes
14 RCT: STARR vs Biofeedback Completed NCT00556283 Phase 4
15 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS) Completed NCT00256984 Phase 4
16 Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery Completed NCT01735851 Phase 4 Thoracic epidural analgesia
17 Predictive Factors of Intestinal Infraction in Acute Mesenteric Ischemia Completed NCT02645240 Phase 4 Heparin injection
18 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Recruiting NCT02812186 Phase 4 Rocuronium
19 Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery Recruiting NCT02056405 Phase 4 Mosapride;Placebo
20 Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway Recruiting NCT02425774 Phase 4 Prucalopride;Placebo
21 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Recruiting NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
22 Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study Active, not recruiting NCT02542462 Phase 4 Rotarix®,;Rotarix®, with other routine vaccines;RotaTeq®,;RotaTeq®, with other routine vaccines
23 Alvimopan Use in Polytraumatized Patients Not yet recruiting NCT03068975 Phase 4 Alvimopan;Placebo
24 The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus Not yet recruiting NCT03176316 Phase 4 Naloxone
25 A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy Terminated NCT02058290 Phase 4 IV morphine sulfate or Sponsor-approved equivalent;EXPAREL
26 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Terminated NCT01507233 Phase 4 IV morphine sulfate;EXPAREL (bupivacaine liposome injectable suspension)
27 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 Terminated NCT01507220 Phase 4 morphine sulfate;bupivacaine liposome extended-release injectable suspension
28 Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain Unknown status NCT00020605 Phase 3 naloxone hydrochloride
29 Endolaparoscopic Versus Immediate Surgery for Obstructing Colorectal Cancers Unknown status NCT00164879 Phase 3
30 Study of Dexamethasone-Allantoin-Metronidazole (DAM) Solution in the Treatment of Post-Operative Ileus (POI) Unknown status NCT01863407 Phase 3 DAM;Normal Saline
31 Electroacupuncture Versus Fast-track Perioperative Program for Laparoscopic Colorectal Surgery Unknown status NCT02059603 Phase 3
32 Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma Unknown status NCT00410631 Phase 3 carboplatin;cisplatin;cyclophosphamide;dacarbazine;doxorubicin hydrochloride;etoposide phosphate;ifosfamide;isotretinoin;melphalan;topotecan hydrochloride;vincristine sulfate;vindesine
33 Outcome of Palliative Management of Malignant Large Bowel Obstruction w/Colorectal Stents or Surgery Completed NCT00140868 Phase 3
34 Bioresorbable Membrane to Reduce Postoperative Small Bowel Obstruction Completed NCT00529412 Phase 3
35 Efficacy and Safety of Lanreotide Microparticles as Palliative Treatment in Peritoneal Carcinomatosis Completed NCT00216372 Phase 3 Lanreotide (microparticle formulation)
36 Randomized Trial of Colonic Stents as a Bridge to Surgery Completed NCT00758186 Phase 3
37 Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting Completed NCT01834430 Phase 3
38 Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures Completed NCT01524081 Phase 3 Metronidazole, Cefuroxime;Amoxicillin (+ clavulanic acid) and Fluconazole;Placebo;Placebo
39 Gastrografin in Postoperative Ileus Completed NCT01648972 Phase 2, Phase 3 Gastrografin;Placebo
40 Randomized Control Trial on Seprafilm and Guardix in Preventing Ileus Completed NCT02168426 Phase 3
41 Pertuzumab in Platinum-Resistant Low Human Epidermal Growth Factor Receptor 3 (HER3) Messenger Ribonucleic Acid (mRNA) Epithelial Ovarian Cancer (PENELOPE) Completed NCT01684878 Phase 3 Gemcitabine (Chemotherapy);Paclitaxel (Chemotherapy);Pertuzumab;Placebo;Topotecan (Chemotherapy)
42 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00205842 Phase 3 alvimopan
43 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00388401 Phase 3 Alvimopan
44 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00388258 Phase 3 Alvimopan
45 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/ Postoperative Ileus Completed NCT00388479 Phase 3 Alvimopan
46 Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus (POI). Completed NCT00401375 Phase 3 Methylnaltrexone;Placebo
47 Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery Completed NCT00464425 Phase 3
48 Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection? Completed NCT01130675 Phase 3
49 The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section Completed NCT01131416 Phase 2, Phase 3
50 Early Versus Interval Appendectomy for Ruptured Appendicitis in Children Completed NCT00435032 Phase 3

Search NIH Clinical Center for Intestinal Obstruction

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: intestinal obstruction

Genetic Tests for Intestinal Obstruction

Genetic tests related to Intestinal Obstruction:

id Genetic test Affiliating Genes
1 Intestinal Obstruction 29

Anatomical Context for Intestinal Obstruction

MalaCards organs/tissues related to Intestinal Obstruction:

39
Colon, Small Intestine, Kidney, Liver, Pancreas, Spleen, Lung

Publications for Intestinal Obstruction

Articles related to Intestinal Obstruction:

(show top 50) (show all 729)
id Title Authors Year
1
Management of a large cystic lymphangioma causing intestinal obstruction. ( 28477401 )
2017
2
A retrospective audit on usage of Diatrizoate Meglumine (Gastrografin(Ar)) for intestinal obstruction or constipation in patients with advanced neoplasms. ( 28805119 )
2017
3
A Rare Case of Bilateral Morgagni's Hernia with Intestinal Obstruction and Malrotation of the Gut in an Adult Patient with Severe Osteogenesis Imperfecta Presenting as Severe Respiratory Distress. ( 28442844 )
2017
4
Giant Fecalith Causing Near Intestinal Obstruction and Rectal Ischemia. ( 28611554 )
2017
5
Peritoneal encapsulationA -A an unexpected cause of acute intestinal obstruction. ( 28688775 )
2017
6
Intestinal obstruction due to kaposiform hemangioendothelioma in a 1-month-old infant: A case report. ( 28906349 )
2017
7
Distal intestinal obstruction syndrome and colonic pathologies in cystic fibrosis. ( 28067560 )
2017
8
Abdominal Plain Radiograph in Neonatal Intestinal Obstruction. ( 28083492 )
2017
9
Gastrointestinal Duplication Presenting as Neonatal Intestinal Obstruction: An Experience of 15 Years at Tertiary Care Centre. ( 28083491 )
2017
10
Meckel's Diverticulum Enterolith: An Extremely Rare Cause of Intestinal Obstruction. ( 28571210 )
2017
11
Sun Should Not Rise and Set on a Case of Acute Intestinal Obstruction. ( 28500588 )
2017
12
Combined use of single-balloon enteroscope and colonoscope for self-expandable metal stent placement in patients with malignant small intestinal obstruction: a single-center comparative clinical observation. ( 28585148 )
2017
13
Neonatal intestinal obstruction associated with situs inversus totalis: two case reports and a review of the literature. ( 28918753 )
2017
14
Collagenous colitis presenting with skip lesions mimicking Crohn's disease and complicated by intestinal obstruction. ( 28682012 )
2017
15
Superior mesenteric artery syndrome: an uncommon cause of intestinal obstruction. ( 28100055 )
2017
16
Intestinal Obstruction in a Patient with Sclerosing Encapsulating Peritonitis. ( 28458941 )
2017
17
Extensive colorectal lymphomatous polyposis complicated by acute intestinal obstruction: a case report. ( 28705174 )
2017
18
Kawasaki Disease Presenting as Acute Intestinal Obstruction. ( 28694577 )
2017
19
Isolation of Shewanella putrefaciens in an elderly man with subacute intestinal obstruction & appendicitis. ( 28649508 )
2017
20
Laparoscopic resection for Meckel's diverticulum causing intestinal obstruction. ( 28944341 )
2017
21
Peutz-Jeghers syndrome with intermittent upper intestinal obstruction: A case report and review of the literature. ( 28445255 )
2017
22
Effects of herbal medicine Sijunzi decoction on rabbits after relieving intestinal obstruction. ( 28953987 )
2017
23
Large Meckel's Diverticulum and Dilated Adjacent Small Intestine Presenting With Intestinal Obstruction. ( 28899672 )
2017
24
An Unusual Cause of Intestinal Obstruction in a Young Adult Patient: Inflammatory Fibroid Polyp. ( 28758041 )
2017
25
Severe intestinal obstruction due to Strongyloides stercoralis in a pregnant woman. ( 28651833 )
2017
26
Postoperative disseminated intravascular coagulation in a pregnant patient with Blue Rubber Bleb Nevus Syndrome presenting with acute intestinal obstruction: Case report and literature review. ( 28858742 )
2017
27
High ambient temperature and risk of intestinal obstruction in cystic fibrosis. ( 27145507 )
2016
28
Concurrent Occurrence of Tumor in Colon and Small Bowel following Intestinal Obstruction: A Case Report and Review of the Literature. ( 27200205 )
2016
29
Enteric duplication cyst as a leading point for ileoileal intussusception in an adult: A rare cause of complete small intestinal obstruction. ( 27358681 )
2016
30
Congenital Vitelline Band Causing Intestinal Obstruction in an Adult with a Double Inferior Vena Cava. ( 27843667 )
2016
31
Intestinal obstruction caused by giant ileal hamartoma: a case report. ( 27162788 )
2016
32
Acute intestinal obstruction due to a non-involuted uterus after cesarean section: case report. ( 27048040 )
2016
33
Recurrent spontaneous subserosal hematoma of ileum causing intestinal obstruction in a patient with menkes disease: A case report. ( 27631241 )
2016
34
A rare cause of intestinal obstruction in a newborn: Congenital band compression. ( 28058391 )
2016
35
Molecular cytogenetic characterization of inv dup del(8p) in a fetus associated with ventriculomegaly, hypoplastic left heart, polyhydramnios and intestinal obstruction. ( 27343326 )
2016
36
Intestinal obstruction requiring fecal diversion due to rectal hematoma following a hemorrhoid laser procedure (HeLP). ( 27189441 )
2016
37
Wild Banana Seed Phytobezoar Rectal Impaction Causing Intestinal Obstruction. ( 27574355 )
2016
38
Avicenna's View on the Etiologies of Intestinal Obstruction. ( 27168944 )
2016
39
COMPARISON OF COMPUTED TOMOGRAPHY AND ABDOMINAL RADIOGRAPHY FOR DETECTION OF CANINE MECHANICAL INTESTINAL OBSTRUCTION. ( 27038072 )
2016
40
WILKIE'S SYNDROME: A RARE CAUSE OF INTESTINAL OBSTRUCTION. ( 27120748 )
2016
41
Anastomotic Leakage in a Patient with Acute Intestinal Obstruction Secondary to Appendiceal and Ileal Endometriosis: A Case Report. ( 27190890 )
2016
42
An Unusual Case of Intestinal Obstruction in Ulcerative Colitis. ( 27810371 )
2016
43
Spontaneous Intramural Duodenal Hematoma: Pancreatitis, Obstructive Jaundice, and Upper Intestinal Obstruction. ( 27891286 )
2016
44
Ultrasound follow-up in a patient with intestinal obstruction due to post-traumatic intramural duodenal hematoma. ( 27194436 )
2016
45
Subacute intestinal obstruction by enterolith: a case study. ( 27652039 )
2016
46
Congenital Neonatal Intestinal Obstruction: Retrospective Analysis at Tertiary Care Hospital. ( 27896157 )
2016
47
A Rare Cause of Incomplete Intestinal Obstruction. ( 27613261 )
2016
48
Unusual intestinal obstruction due to idiopathic sclerosing encapsulating peritonitis: a report of two cases and a review. ( 27073795 )
2016
49
Congenital Middle Mesocolic Hernia: A Rare Cause of Neonatal Intestinal Obstruction. ( 27896166 )
2016
50
Chylous ascites associated with intestinal obstruction from volvulus due to Petersen's hernia: report of a case. ( 27468960 )
2016

Variations for Intestinal Obstruction

Expression for Intestinal Obstruction

Search GEO for disease gene expression data for Intestinal Obstruction.

Pathways for Intestinal Obstruction

Pathways related to Intestinal Obstruction according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
10.83 CD8A FLNA PDPK1

GO Terms for Intestinal Obstruction

Biological processes related to Intestinal Obstruction according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.83 ACHE EDNRB GDNF NRTN RET
2 positive regulation of cell proliferation GO:0008284 9.8 CDX2 EDN3 EDNRB GDNF NOD2
3 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.7 CD8A NRTN RET
4 positive regulation of cell differentiation GO:0045597 9.54 CDX2 EDN3 GDNF
5 mRNA stabilization GO:0048255 9.51 GDNF MTOR
6 melanocyte differentiation GO:0030318 9.49 EDN3 EDNRB
7 vasoconstriction GO:0042310 9.48 EDN3 EDNRB
8 positive regulation of potassium ion transmembrane transport GO:1901381 9.46 EDN3 FLNA
9 vein smooth muscle contraction GO:0014826 9.32 EDN3 EDNRB
10 positive regulation of neuron maturation GO:0014042 9.26 MTOR RET
11 posterior midgut development GO:0007497 9.16 EDNRB RET
12 enteric nervous system development GO:0048484 9.13 EDNRB GDNF RET
13 neural crest cell migration GO:0001755 9.02 EDN3 EDNRB GDNF NRTN RET

Molecular functions related to Intestinal Obstruction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ATP binding GO:0005524 9.7 CFTR GUCY2C MTOR MVK NOD2 PDPK1
2 protein binding GO:0005515 9.53 ACHE CD8A CFTR EDNRB FLNA GDNF
3 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.13 GDNF NRTN RET

Sources for Intestinal Obstruction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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