MCID: INT070
MIFTS: 57

Intestinal Obstruction malady

Categories: Fetal diseases, Gastrointestinal diseases, Rare diseases, Neuronal diseases

Aliases & Classifications for Intestinal Obstruction

Summaries for Intestinal Obstruction

MedlinePlus : 41 an intestinal obstruction occurs when food or stool cannot move through the intestines. the obstruction can be complete or partial. there are many causes. the most common are adhesions, hernias, cancers, and certain medicines. symptoms include severe abdominal pain or cramping vomiting bloating loud bowel sounds swelling of the abdomen inability to pass gas constipation a complete intestinal obstruction is a medical emergency. it often requires surgery. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Intestinal Obstruction is related to hirschsprung disease 1 and meconium ileus, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Intestinal Obstruction is ACHE (Acetylcholinesterase (Cartwright Blood Group)), and among its related pathways/superpathways is Biogenic Amine Synthesis. The drugs Dexmedetomidine and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include small intestine, kidney and colon, and related phenotypes are behavior/neurological and digestive/alimentary

Related Diseases for Intestinal Obstruction

Diseases in the Intestinal Obstruction family:

Intestinal Pseudo-Obstruction

Diseases related to Intestinal Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 252)
id Related Disease Score Top Affiliating Genes
1 hirschsprung disease 1 31.5 EDNRB GDNF RET
2 meconium ileus 11.9
3 peritonitis 11.1
4 visceral myopathy 11.1
5 wandering spleen 11.1
6 intestinal pseudoobstruction, neuronal 10.9
7 chronic atrial and intestinal dysrhythmia 10.7
8 hirschsprung disease 3 10.7
9 hirschsprung disease 2 10.7
10 hirschsprung disease 4 10.7
11 polyposis, juvenile intestinal 10.7
12 duodenal atresia 10.7
13 diphyllobothriasis 10.7
14 hereditary angioedema 10.7
15 colonic pseudo-obstruction 10.7
16 intestinal pseudo-obstruction 10.7
17 fasciolopsiasis 10.7
18 actg2-related disorders 10.7
19 abdominal cystic lymphangioma 10.7
20 hypoganglionosis 10.7
21 intussusception 10.6
22 paralytic ileus 10.5
23 intestinal volvulus 10.4
24 epiphyseal dysplasia, multiple, 3 10.3 EDN3 EDNRB
25 waardenburg syndrome, type 4a 10.3 EDNRB RET
26 meigel disease 10.3 GDNF RET
27 wdha syndrome 10.3 EDN3 EDNRB
28 ceroid lipofuscinosis, neuronal, 5 10.3 EDN3 EDNRB RET
29 apocrine adenoma 10.3 EDNRB FLNA RET
30 hypoparathyroidism-intellectual disability-dysmorphism syndrome 10.3 ACHE GDNF RET
31 neutropenia, severe congenital, 5, autosomal recessive 10.2 EDNRB GDNF RET
32 shprintzen-goldberg syndrome 10.2 EDN3 EDNRB GDNF RET
33 herpetic whitlow 10.2 CD8A FLNA RET
34 chronic infections, due to mbl deficiency 10.2 EDN3 EDNRB GDNF RET
35 myopathy of extraocular muscle 10.2 EDN3 EDNRB RET
36 sweat gland cancer 10.2 EDNRB FLNA GDNF RET
37 vestibulocochlear nerve disease 10.2 GDNF HDC RET
38 familial cold autoinflammatory syndrome 4 10.2 ACHE RET
39 pancreatic agenesis 2 10.1 CFTR GDNF RET
40 clitoris cancer 10.1 CDX2 KRT20
41 cystic fibrosis 10.1
42 uterine ligament clear cell adenocarcinoma 10.1 EDNRB NOD2 RET
43 extramedullary plasmacytoma 10.1 CDX2 KRT20
44 intestinal disease 10.0
45 synovitis 10.0 CDX2 KRT7
46 meckel's diverticulum 10.0
47 cervix endometriosis 10.0 CDX2 KRT20
48 spinal meningioma 10.0 ACHE EDN3 EDNRB GDNF NRTN RET
49 radiculopathy 10.0 KRT20 KRT7
50 tooth agenesis, selective, 5 10.0 ACHE EDN3 EDNRB GDNF NRTN RET

Comorbidity relations with Intestinal Obstruction via Phenotypic Disease Network (PDN): (show top 50) (show all 58)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Anxiety Disorder Ascending Colon Cancer
Bronchitis Candidiasis
Cecal Benign Neoplasm Cervical Cancer, Somatic
Chronic Kidney Failure Chronic Myocardial Ischemia
Chylomicron Retention Disease Colorectal Cancer
Crohn's Disease Decubitus Ulcer
Deficiency Anemia Descending Colon Cancer
Enterovesical Fistula Esophageal Disease
Esophagitis Familial Atrial Fibrillation
Gastric Cancer, Somatic Gastrointestinal System Cancer
Generalized Atherosclerosis Heart Disease
Hepatic Flexure Cancer Hydronephrosis
Hypertension, Essential Hypothyroidism
Inflammatory Bowel Disease 1 Intestinal Disease
Intestinal Perforation Intestinal Volvulus
Iron Deficiency Anemia Irritable Bowel Syndrome
Jejunal Cancer Kidney Disease
Marasmus Mesenteric Artery Ischemia
Neutropenia Osteoporosis
Ovarian Cancer, Somatic Pancreatic Cancer
Pancreatitis, Hereditary Paralytic Ileus
Peritonitis Postgastrectomy Syndrome
Protein-Energy Malnutrition Radiation Cystitis

Graphical network of the top 20 diseases related to Intestinal Obstruction:



Diseases related to Intestinal Obstruction

Symptoms & Phenotypes for Intestinal Obstruction

UMLS symptoms related to Intestinal Obstruction:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

MGI Mouse Phenotypes related to Intestinal Obstruction:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.23 ACHE CFTR EDN3 EDNRB FLNA GDNF
2 digestive/alimentary MP:0005381 10.14 CDX2 CFTR EDN3 EDNRB FLNA GDNF
3 cellular MP:0005384 10.13 CD8A CDX2 EDNRB FLNA GDNF KRT7
4 growth/size/body region MP:0005378 10.06 ACHE CDX2 CFTR EDNRB FLNA GDNF
5 homeostasis/metabolism MP:0005376 10.03 ACHE CDX2 CFTR EDNRB FLNA GUCY2C
6 endocrine/exocrine gland MP:0005379 10.02 NRTN RET SGO1 CD8A CDX2 CFTR
7 immune system MP:0005387 9.9 CD8A CFTR EDNRB FLNA GDNF GUCY2C
8 mortality/aging MP:0010768 9.77 CD8A CDX2 CFTR EDN3 EDNRB FLNA
9 nervous system MP:0003631 9.32 EDN3 EDNRB FLNA GDNF HDC MTOR

Drugs & Therapeutics for Intestinal Obstruction

Drugs for Intestinal Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 503)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 1,Phase 2 76631-46-4, 113775-47-6 68602 5311068 56032
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2 137-58-6 3676
3
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
4
Ropivacaine Approved Phase 4,Phase 3,Phase 2 84057-95-4 71273 175805
5
Ertapenem Approved, Investigational Phase 4,Phase 2 153832-46-3 150610
6
Clonidine Approved Phase 4 4205-90-7 2803
7
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
8
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 57-27-2 5288826
9
Metformin Approved Phase 4,Phase 1 657-24-9 14219 4091
10
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3 9004-61-9 53477741 24759
11
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
12
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
13
Sevoflurane Approved, Vet_approved Phase 4,Phase 2 28523-86-6 5206
14
Ondansetron Approved Phase 4,Phase 3 99614-02-5 4595
15
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2180-92-9, 38396-39-3 2474
16
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
17
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
18
Maraviroc Approved, Investigational Phase 4 376348-65-1 3002977
19
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
20
Hydromorphone Approved, Illicit Phase 4,Phase 3,Phase 2 466-99-9 5284570
21
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
22
Etomidate Approved Phase 4,Phase 2 33125-97-2 36339 667484
23
Dimenhydrinate Approved Phase 4 523-87-5 441281
24
Menthol Approved Phase 4 2216-51-5 16666
25
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2 437-38-7 3345
26
Sufentanil Approved, Investigational Phase 4,Phase 2 56030-54-7 41693
27
Alvimopan Approved Phase 4,Phase 3 156053-89-3 5488548
28
Prilocaine Approved Phase 4 721-50-6 4906
29
Somatostatin Approved Phase 4,Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
30 Simethicone Approved Phase 4
31
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
32
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
33
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
34
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
35
Methadone Approved Phase 4 76-99-3 4095
36
Vancomycin Approved Phase 4,Phase 3 1404-90-6 441141 14969
37
Orphenadrine Approved Phase 4 83-98-7 4601
38
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
39
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
40
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3 76-42-6 5284603
41
Dalteparin Approved Phase 4 9041-08-1
42
Guaifenesin Approved, Vet_approved Phase 4 93-14-1 3516
43
Vedolizumab Approved Phase 4 943609-66-3
44
Baclofen Approved Phase 4 1134-47-0 2284
45 tannic acid Approved, Nutraceutical Phase 4,Phase 2
46 Analgesics Phase 4,Phase 3,Phase 1,Phase 2
47
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
48 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2
49 Adrenergic Agents Phase 4,Phase 2,Phase 3,Phase 1
50 Narcotics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 565)
id Name Status NCT ID Phase
1 New Adjuvant Chemotherapy of Non Resectable Liver Metastasis of Colorectal Cancer Without Bleeding, Obstruction Unknown status NCT01307878 Phase 4
2 A Comparison of Dexmedetomidine and Epidural Anesthesia Under General Anesthesia in Patients Undergoing Gastrectomy Unknown status NCT01657812 Phase 4
3 Antibiotics Versus Surgery in Acute Appendicitis Unknown status NCT01421901 Phase 4
4 Identifying the Effect of Somatostatin Treatment in Early Postoperative Simple Small Bowel Obstruction Completed NCT01082627 Phase 4
5 (Gastrografin Use in Small Bowel Obstruction Caused by Adherences) Completed NCT00601809 Phase 4
6 Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction Completed NCT00389116 Phase 4
7 SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery Completed NCT00531739 Phase 4
8 The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery Completed NCT02773251 Phase 4
9 Adult Patients Undergoing Open Colectomy MA402S23B303 Completed NCT01507246 Phase 4
10 Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy Completed NCT00934999 Phase 4
11 Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery Completed NCT02161367 Phase 4
12 A New Approach of Neostigmine in Unavoidable Post Operative Ileus Completed NCT00676377 Phase 4
13 Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation Completed NCT01956643 Phase 4
14 Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery Completed NCT01440712 Phase 4
15 A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy Completed NCT00708201 Phase 4
16 Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children Completed NCT01592734 Phase 4
17 RCT: STARR vs Biofeedback Completed NCT00556283 Phase 4
18 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS) Completed NCT00256984 Phase 4
19 Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery Completed NCT01735851 Phase 4
20 TAP Block in DIEP or Free MS-TRAM Donor Site: A RCT Completed NCT01398982 Phase 4
21 Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women Completed NCT01827280 Phase 4
22 Ondansetron for the Treatment of IBS With Diarrhoea (IBS-D) Completed NCT00745004 Phase 4
23 Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants Completed NCT02140710 Phase 4
24 TAP Block Efficacy After Lumbar Spine Surgery Through Anterior Approach: a Randomized, Placebo-controlled Study Completed NCT02778178 Phase 4
25 A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy Completed NCT00870363 Phase 4
26 Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children Completed NCT03005808 Phase 4
27 A Comparison of UGBRS Block and Local Infiltration Completed NCT02352519 Phase 4
28 Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl Completed NCT01880775 Phase 4
29 Once Versus Twice Daily Mesalamine to Induce Remission in Pediatric Ulcerative Colitis Completed NCT01201122 Phase 4
30 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Recruiting NCT02812186 Phase 4
31 Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery Recruiting NCT02056405 Phase 4
32 Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway Recruiting NCT02425774 Phase 4
33 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Recruiting NCT02958566 Phase 4
34 Predictive Factors of Intestinal Infraction in Acute Mesenteric Ischemia Recruiting NCT02645240 Phase 4
35 Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis Patients Recruiting NCT02605213 Phase 4
36 Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils Recruiting NCT01943409 Phase 4
37 Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas Recruiting NCT01023984 Phase 4
38 HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial Recruiting NCT02216305 Phase 4
39 A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric Patients Active, not recruiting NCT02722057 Phase 4
40 Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study Active, not recruiting NCT02542462 Phase 4
41 Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml. Active, not recruiting NCT01948245 Phase 4
42 Alvimopan Use in Polytraumatized Patients Not yet recruiting NCT03068975 Phase 4
43 The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus Not yet recruiting NCT03176316 Phase 4
44 Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG Not yet recruiting NCT02727712 Phase 4
45 Multi-Drug Analgesia vs. Standard Solution for Anal Surgery Not yet recruiting NCT03105674 Phase 4
46 Effectiveness of Vedolizumab in CD Patients Naïve to Anti-TNF Not yet recruiting NCT02820493 Phase 4
47 A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy Terminated NCT02058290 Phase 4
48 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Terminated NCT01507233 Phase 4
49 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 Terminated NCT01507220 Phase 4
50 Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen Terminated NCT01003249 Phase 4

Search NIH Clinical Center for Intestinal Obstruction

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: intestinal obstruction

Genetic Tests for Intestinal Obstruction

Genetic tests related to Intestinal Obstruction:

id Genetic test Affiliating Genes
1 Intestinal Obstruction 29

Anatomical Context for Intestinal Obstruction

MalaCards organs/tissues related to Intestinal Obstruction:

39
Small Intestine, Kidney, Colon, Spleen, Lung, Myeloid, Appendix

Publications for Intestinal Obstruction

Articles related to Intestinal Obstruction:

(show top 50) (show all 705)
id Title Authors Year
1
Abdominal Plain Radiograph in Neonatal Intestinal Obstruction. ( 28083492 )
2017
2
Peutz-Jeghers syndrome with intermittent upper intestinal obstruction: A case report and review of the literature. ( 28445255 )
2017
3
Distal intestinal obstruction syndrome and colonic pathologies in cystic fibrosis. ( 28067560 )
2017
4
Gastrointestinal Duplication Presenting as Neonatal Intestinal Obstruction: An Experience of 15 Years at Tertiary Care Centre. ( 28083491 )
2017
5
A Rare Case of Bilateral Morgagni's Hernia with Intestinal Obstruction and Malrotation of the Gut in an Adult Patient with Severe Osteogenesis Imperfecta Presenting as Severe Respiratory Distress. ( 28442844 )
2017
6
Spontaneous Intramural Duodenal Hematoma: Pancreatitis, Obstructive Jaundice, and Upper Intestinal Obstruction. ( 27891286 )
2016
7
An Unusual Case of Intestinal Obstruction in Ulcerative Colitis. ( 27810371 )
2016
8
Ultrasound follow-up in a patient with intestinal obstruction due to post-traumatic intramural duodenal hematoma. ( 27194436 )
2016
9
Neonatal Intestinal Obstruction: A 15 Year Experience in a Tertiary Care Hospital. ( 27042546 )
2016
10
Clinical strategies for the management of intestinal obstruction and pseudo-obstruction. A Delphi Consensus study of SICUT (SocietA Italiana di Chirurgia d'Urgenza e del Trauma). ( 27179226 )
2016
11
Acute intestinal obstruction due to a non-involuted uterus after cesarean section: case report. ( 27048040 )
2016
12
WILKIE'S SYNDROME: A RARE CAUSE OF INTESTINAL OBSTRUCTION. ( 27120748 )
2016
13
Recurrent spontaneous subserosal hematoma of ileum causing intestinal obstruction in a patient with menkes disease: A case report. ( 27631241 )
2016
14
Intestinal obstruction following a hemorrhoid laser procedure (HeLP). ( 27573196 )
2016
15
Avicenna's View on the Etiologies of Intestinal Obstruction. ( 27168944 )
2016
16
A Case of Intestinal Obstruction in Pregnancy Diagnosed by MRI and Treated by Intravenous Hyperalimentation. ( 27999695 )
2016
17
Question 8: How should distal intestinal obstruction syndrome [DIOS] be managed? ( 27425011 )
2016
18
Unusual intestinal obstruction due to idiopathic sclerosing encapsulating peritonitis: a report of two cases and a review. ( 27073795 )
2016
19
A butterfly in the belly: an unusual cause of intestinal obstruction. ( 27323677 )
2016
20
A rare cause of intestinal obstruction in a newborn: Congenital band compression. ( 28058391 )
2016
21
Enteric duplication cyst as a leading point for ileoileal intussusception in an adult: A rare cause of complete small intestinal obstruction. ( 27358681 )
2016
22
Congenital Middle Mesocolic Hernia: A Rare Cause of Neonatal Intestinal Obstruction. ( 27896166 )
2016
23
Neonatal Intestinal Obstruction: When to Suspect Duplication Cyst of Bowel as the Cause. ( 27896160 )
2016
24
Concurrent Occurrence of Tumor in Colon and Small Bowel following Intestinal Obstruction: A Case Report and Review of the Literature. ( 27200205 )
2016
25
Superior Mesentric Artery Syndrome in a Patient with Subacute Intestinal Obstruction: A Case Report. ( 27504378 )
2016
26
Ileal stricture following Meckel's diverticulitis: a rare cause of intestinal obstruction. ( 27146826 )
2016
27
Congenital Neonatal Intestinal Obstruction: Retrospective Analysis at Tertiary Care Hospital. ( 27896157 )
2016
28
Intestinal Obstruction and Ileocolic Fistula due to Intraluminal Migration of a Gossypiboma. ( 26989551 )
2016
29
Appendicular Tourniquet: A Cause of Intestinal Obstruction. ( 27437300 )
2016
30
Congenital Vitelline Band Causing Intestinal Obstruction in an Adult with a Double Inferior Vena Cava. ( 27843667 )
2016
31
Answer to Photo Quiz: A butterfly in the belly: an unusual cause of intestinal obstruction. ( 27323678 )
2016
32
The Spectrum of Paediatric Intestinal Obstruction in Kenya. ( 27642384 )
2016
33
Appendicular bilharzioma: An unusual cause of acute intestinal obstruction in childhood (a case report at Charles de Gaulle Paediatric Teaching Hospital of Ouagadougou). ( 28051054 )
2016
34
Chylous ascites associated with intestinal obstruction from volvulus due to Petersen's hernia: report of a case. ( 27468960 )
2016
35
A Rare Type of Primary Internal Hernia Causing Small Intestinal Obstruction. ( 27999703 )
2016
36
Clinical Profile of Patients with Postoperative Adhesive Intestinal Obstruction and its Association with Intraoperative Peritoneal Adhesion Index. ( 27452937 )
2016
37
Molecular cytogenetic characterization of inv dup del(8p) in a fetus associated with ventriculomegaly, hypoplastic left heart, polyhydramnios and intestinal obstruction. ( 27343326 )
2016
38
Intestinal obstruction caused by giant ileal hamartoma: a case report. ( 27162788 )
2016
39
Subacute intestinal obstruction by enterolith: a case study. ( 27652039 )
2016
40
Jejunal Windsock Deformity: A Rare Cause of Incomplete Neonatal Intestinal Obstruction. ( 27896165 )
2016
41
Muscular Hamartoma of Intestine Causing Intestinal Obstruction. ( 27935929 )
2016
42
Late intestinal obstruction after radical cystectomy and urinary diversion: urological and oncological perspectives. ( 27589558 )
2016
43
Intestinal Obstruction Caused by Ileocolic and Colocolic Intussusception in an Adult Patient with Cecal Lipoma. ( 28044120 )
2016
44
Congenital transmesenteric hernia presenting with intestinal obstruction in an adult: a case report. ( 27459082 )
2016
45
Idiopathic Sclerosing Encapsulating Peritonitis: A Rare Cause of Subacute Intestinal Obstruction. ( 27642301 )
2016
46
COMPARISON OF COMPUTED TOMOGRAPHY AND ABDOMINAL RADIOGRAPHY FOR DETECTION OF CANINE MECHANICAL INTESTINAL OBSTRUCTION. ( 27038072 )
2016
47
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
48
High ambient temperature and risk of intestinal obstruction in cystic fibrosis. ( 27145507 )
2016
49
Wild Banana Seed Phytobezoar Rectal Impaction Causing Intestinal Obstruction. ( 27574355 )
2016
50
Anastomotic Leakage in a Patient with Acute Intestinal Obstruction Secondary to Appendiceal and Ileal Endometriosis: A Case Report. ( 27190890 )
2016

Variations for Intestinal Obstruction

Expression for Intestinal Obstruction

Search GEO for disease gene expression data for Intestinal Obstruction.

Pathways for Intestinal Obstruction

Pathways related to Intestinal Obstruction according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
9.97 ACHE HDC

GO Terms for Intestinal Obstruction

Biological processes related to Intestinal Obstruction according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.83 ACHE EDNRB GDNF NRTN RET
2 positive regulation of cell proliferation GO:0008284 9.8 CDX2 EDN3 EDNRB GDNF NOD2
3 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.7 CD8A NRTN RET
4 response to pain GO:0048265 9.54 EDNRB RET
5 positive regulation of cell differentiation GO:0045597 9.54 CDX2 EDN3 GDNF
6 melanocyte differentiation GO:0030318 9.51 EDN3 EDNRB
7 mRNA stabilization GO:0048255 9.49 GDNF MTOR
8 vasoconstriction GO:0042310 9.48 EDN3 EDNRB
9 positive regulation of potassium ion transmembrane transport GO:1901381 9.46 EDN3 FLNA
10 vein smooth muscle contraction GO:0014826 9.32 EDN3 EDNRB
11 positive regulation of neuron maturation GO:0014042 9.26 MTOR RET
12 posterior midgut development GO:0007497 9.16 EDNRB RET
13 enteric nervous system development GO:0048484 9.13 EDNRB GDNF RET
14 neural crest cell migration GO:0001755 9.02 EDN3 EDNRB GDNF NRTN RET

Molecular functions related to Intestinal Obstruction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.8 GDNF NRTN RET

Sources for Intestinal Obstruction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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