MCID: INT070
MIFTS: 55

Intestinal Obstruction

Categories: Fetal diseases, Rare diseases, Gastrointestinal diseases, Neuronal diseases, Genetic diseases

Aliases & Classifications for Intestinal Obstruction

Summaries for Intestinal Obstruction

MedlinePlus : 40 An intestinal obstruction occurs when food or stool cannot move through the intestines. The obstruction can be complete or partial. There are many causes. The most common are adhesions, hernias, cancers, and certain medicines. Symptoms include Severe abdominal pain or cramping Vomiting Bloating Loud bowel sounds Swelling of the abdomen Inability to pass gas Constipation A complete intestinal obstruction is a medical emergency. It often requires surgery. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Intestinal Obstruction is related to intestinal pseudo-obstruction and hypoganglionosis, and has symptoms including gastrointestinal gas, nausea and vomiting and icterus. An important gene associated with Intestinal Obstruction is GDNF (Glial Cell Derived Neurotrophic Factor). The drugs Naloxone and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and kidney, and related phenotypes are behavior/neurological and digestive/alimentary

Related Diseases for Intestinal Obstruction

Diseases in the Intestinal Obstruction family:

Intestinal Pseudo-Obstruction

Diseases related to Intestinal Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 318)
# Related Disease Score Top Affiliating Genes
1 intestinal pseudo-obstruction 32.2 EDNRB FLNA RET SGO1
2 hypoganglionosis 31.0 ACHE BLVRB GDNF RET
3 intestinal disease 30.8 EDNRB NOD2 RET
4 constipation 30.3 EDNRB FLNA GDNF RET
5 hirschsprung disease 1 30.2 ACHE BLVRB EDN3 EDNRB GDNF NRTN
6 teratoma 30.0 CDX2 KRT20 KRT7
7 cystic teratoma 29.8 CDX2 KRT20 KRT7
8 pseudomyxoma peritonei 29.8 CDX2 KRT20 KRT7
9 jejunal adenocarcinoma 29.6 CDX2 KRT20 KRT7
10 intrahepatic cholangiocarcinoma 29.5 CDX2 KRT20 KRT7
11 cholangiocarcinoma 29.1 CDX2 KRT20 KRT7
12 meconium ileus 12.0
13 intestinal pseudoobstruction, neuronal, chronic idiopathic, x-linked 11.3
14 peritonitis 11.2
15 wandering spleen 11.2
16 visceral myopathy 11.2
17 congenital chloride diarrhea 11.1
18 juvenile polyposis syndrome 10.8
19 duodenal atresia 10.8
20 gastrointestinal defects and immunodeficiency syndrome 10.8
21 hirschsprung disease 2 10.8
22 ascaris lumbricoides infection 10.8
23 hirschsprung disease 3 10.8
24 hirschsprung disease 4 10.8
25 chronic atrial and intestinal dysrhythmia 10.8
26 diphyllobothriasis 10.8
27 pica disease 10.8
28 colonic pseudo-obstruction 10.8
29 fasciolopsiasis 10.8
30 actg2-related disorders 10.8
31 abdominal cystic lymphangioma 10.8
32 desmoid tumor 10.8
33 intussusception 10.6
34 medullary sponge kidney 10.6 GDNF RET
35 waardenburg syndrome type 4 10.6 EDN3 EDNRB
36 paralytic ileus 10.5
37 ovarian germ cell teratoma 10.5 KRT7 RET
38 multiple endocrine neoplasia, type iib 10.5 EDNRB GDNF RET
39 waardenburg syndrome, type 4a 10.5 EDN3 EDNRB RET
40 ovarian germ cell cancer 10.5 KRT7 RET
41 thyroid carcinoma, familial medullary 10.4 EDNRB GDNF RET
42 mucinous adenofibroma 10.4 CDX2 KRT7
43 cystic basal cell carcinoma 10.4 KRT20 KRT7
44 intestinal volvulus 10.4
45 lichen nitidus 10.4 FLNA RET
46 lung acinar adenocarcinoma 10.4 KRT20 KRT7
47 seminal vesicle adenocarcinoma 10.4 KRT20 KRT7
48 transverse colon cancer 10.4 KRT20 KRT7
49 ovarian large-cell neuroendocrine carcinoma 10.4 KRT20 KRT7
50 anal canal adenocarcinoma 10.4 CDX2 KRT7

Comorbidity relations with Intestinal Obstruction via Phenotypic Disease Network (PDN): (show top 50) (show all 59)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Acute Vascular Insufficiency of Intestine Anxiety
Ascending Colon Cancer Bronchitis
Candidiasis Cecal Benign Neoplasm
Cervical Cancer Chronic Intestinal Vascular Insufficiency
Chronic Kidney Failure Chronic Myocardial Ischemia
Chylomicron Retention Disease Colorectal Cancer
Crohn's Disease Decubitus Ulcer
Deficiency Anemia Descending Colon Cancer
Enterovesical Fistula Esophageal Disease
Esophagitis Familial Atrial Fibrillation
Gastric Cancer Gastrointestinal System Cancer
Generalized Atherosclerosis Heart Disease
Hepatic Flexure Cancer Hydronephrosis
Hypertension, Essential Hypothyroidism
Inflammatory Bowel Disease 1 Intestinal Disease
Intestinal Perforation Intestinal Volvulus
Iron Deficiency Anemia Irritable Bowel Syndrome
Jejunal Cancer Kidney Disease
Marasmus Neutropenia
Osteoporosis Ovarian Cancer
Pancreatic Cancer Pancreatitis, Hereditary
Paralytic Ileus Peritonitis
Postgastrectomy Syndrome Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Intestinal Obstruction:



Diseases related to Intestinal Obstruction

Symptoms & Phenotypes for Intestinal Obstruction

UMLS symptoms related to Intestinal Obstruction:


gastrointestinal gas, nausea and vomiting, icterus, heartburn, dyspepsia, diarrhea, constipation, abdominal pain

MGI Mouse Phenotypes related to Intestinal Obstruction:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.26 GDNF GUCY2C HDC MTOR NRTN RET
2 digestive/alimentary MP:0005381 10.17 CDX2 CFTR EDN3 EDNRB FLNA GDNF
3 cellular MP:0005384 10.16 CDX2 EDNRB FLNA GDNF KRT7 MTOR
4 growth/size/body region MP:0005378 10.11 ACHE CDX2 CFTR EDNRB FLNA GDNF
5 homeostasis/metabolism MP:0005376 10.07 ACHE BLVRB CDX2 CFTR EDNRB FLNA
6 endocrine/exocrine gland MP:0005379 10.06 CD8A CDX2 CFTR EDNRB GDNF MTOR
7 hematopoietic system MP:0005397 10.02 EDNRB FLNA GDNF HDC MTOR NOD2
8 immune system MP:0005387 9.9 CD8A CFTR EDNRB FLNA GDNF GUCY2C
9 mortality/aging MP:0010768 9.77 GUCY2C MTOR NOD2 RET SGO1 ACHE
10 nervous system MP:0003631 9.32 ACHE CD8A EDN3 EDNRB FLNA GDNF

Drugs & Therapeutics for Intestinal Obstruction

Drugs for Intestinal Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 257)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Naloxone Approved, Vet_approved Phase 4,Phase 3,Phase 1 465-65-6 5284596
2
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
3
Morphine Approved, Investigational Phase 4 57-27-2 5288826
4
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3 9004-61-9 53477741 24759
5
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
6
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
7
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
8
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
9
Dimenhydrinate Approved Phase 4 523-87-5 441281
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
11
Alvimopan Approved, Investigational Phase 4,Phase 3,Phase 2 156053-89-3 5488548
12
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
13 Simethicone Approved Phase 4
14
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
15
Acetaminophen Approved Phase 4 103-90-2 1983
16
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
17
Lidocaine Approved, Vet_approved Phase 4,Phase 2 137-58-6 3676
18
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
19
Methadone Approved Phase 4 76-99-3 4095
20
Orphenadrine Approved Phase 4 83-98-7 4601
21
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
22
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
23
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
24
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
25 tannic acid Approved, Nutraceutical Phase 4
26 Mosapride Investigational Phase 4 112885-41-3
27
Serotonin Phase 4,Phase 1,Phase 2 50-67-9 5202
28 Analgesics Phase 4,Phase 1
29 Central Nervous System Depressants Phase 4,Phase 2,Phase 1
30 Serotonin Agents Phase 4
31 Narcotic Antagonists Phase 4,Phase 3,Phase 2,Phase 1
32 Narcotics Phase 4,Phase 3,Phase 2,Phase 1
33 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Neurotransmitter Agents Phase 4,Phase 1,Phase 2
35 Analgesics, Non-Narcotic Phase 4,Phase 1
36 Anesthetics Phase 4,Phase 2
37 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
38 Dermatologic Agents Phase 4,Phase 3
39 Anesthetics, General Phase 4
40 Anesthetics, Intravenous Phase 4
41 Anesthetics, Local Phase 4,Phase 2
42 Hormones Phase 4,Phase 3,Phase 2,Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
44 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
46 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Liver Extracts Phase 4,Phase 2,Phase 1
48 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Antirheumatic Agents Phase 4,Phase 3,Phase 1
50 Cathartics Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 219)

# Name Status NCT ID Phase Drugs
1 Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery Unknown status NCT02056405 Phase 4 Mosapride;Placebo
2 Identifying the Effect of Somatostatin Treatment in Early Postoperative Simple Small Bowel Obstruction Completed NCT01082627 Phase 4 Somatostatin
3 (Gastrografin Use in Small Bowel Obstruction Caused by Adherences) Completed NCT00601809 Phase 4 Gastrografin®: G
4 Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction Completed NCT00389116 Phase 4 gastrograffin;water
5 SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery Completed NCT00531739 Phase 4
6 The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery Completed NCT02773251 Phase 4 hyaluronic acid-carboxymethylcellulose
7 Adult Patients Undergoing Open Colectomy MA402S23B303 Completed NCT01507246 Phase 4 IV morphine sulfate;EXPAREL (bupivacaine liposome injectable suspension)
8 Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy Completed NCT00934999 Phase 4
9 Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery Completed NCT02161367 Phase 4 Simethicone;Oral Suspending Vehicle
10 Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation Completed NCT01956643 Phase 4
11 Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery Completed NCT01440712 Phase 4 Gastrografin;physiological serum
12 A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy Completed NCT00708201 Phase 4 Alvimopan;Placebo
13 A New Approach of Neostigmine in Unavoidable Post Operative Ileus Completed NCT00676377 Phase 4 Neostigmine;Saline
14 Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children Completed NCT01592734 Phase 4 Polyethylene glycol with electrolytes
15 RCT: STARR vs Biofeedback Completed NCT00556283 Phase 4
16 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS) Completed NCT00256984 Phase 4
17 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Recruiting NCT02812186 Phase 4 Rocuronium
18 The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus Recruiting NCT03176316 Phase 4 Naloxone
19 Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway Recruiting NCT02425774 Phase 4 Prucalopride;Placebo
20 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Recruiting NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
21 Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study Active, not recruiting NCT02542462 Phase 4 Rotarix®,;Rotarix®, with other routine vaccines;RotaTeq®,;RotaTeq®, with other routine vaccines
22 The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients. Not yet recruiting NCT03334578 Phase 4 Gastrografin
23 Alvimopan Use in Polytraumatized Patients Not yet recruiting NCT03068975 Phase 4 Alvimopan;Placebo
24 A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy Terminated NCT02058290 Phase 4 IV morphine sulfate or Sponsor-approved equivalent;EXPAREL
25 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Terminated NCT01507233 Phase 4 IV morphine sulfate;EXPAREL (bupivacaine liposome injectable suspension)
26 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 Terminated NCT01507220 Phase 4 morphine sulfate;bupivacaine liposome extended-release injectable suspension
27 Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain Unknown status NCT00020605 Phase 3 naloxone hydrochloride
28 Endolaparoscopic Versus Immediate Surgery for Obstructing Colorectal Cancers Unknown status NCT00164879 Phase 3
29 Study of Dexamethasone-Allantoin-Metronidazole (DAM) Solution in the Treatment of Post-Operative Ileus (POI) Unknown status NCT01863407 Phase 3 DAM;Normal Saline
30 Electroacupuncture Versus Fast-track Perioperative Program for Laparoscopic Colorectal Surgery Unknown status NCT02059603 Phase 3
31 Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma Unknown status NCT00410631 Phase 3 carboplatin;cisplatin;cyclophosphamide;dacarbazine;doxorubicin hydrochloride;etoposide phosphate;ifosfamide;isotretinoin;melphalan;topotecan hydrochloride;vincristine sulfate;vindesine
32 Outcome of Palliative Management of Malignant Large Bowel Obstruction w/Colorectal Stents or Surgery Completed NCT00140868 Phase 3
33 Bioresorbable Membrane to Reduce Postoperative Small Bowel Obstruction Completed NCT00529412 Phase 3
34 Efficacy and Safety of Lanreotide Microparticles as Palliative Treatment in Peritoneal Carcinomatosis Completed NCT00216372 Phase 3 Lanreotide (microparticle formulation)
35 Randomized Trial of Colonic Stents as a Bridge to Surgery Completed NCT00758186 Phase 3
36 Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting Completed NCT01834430 Phase 3
37 Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures Completed NCT01524081 Phase 3 Metronidazole, Cefuroxime;Amoxicillin (+ clavulanic acid) and Fluconazole;Placebo;Placebo
38 Gastrografin in Postoperative Ileus Completed NCT01648972 Phase 2, Phase 3 Gastrografin;Placebo
39 Randomized Control Trial on Seprafilm and Guardix in Preventing Ileus Completed NCT02168426 Phase 3
40 Pertuzumab in Platinum-Resistant Low Human Epidermal Growth Factor Receptor 3 (HER3) Messenger Ribonucleic Acid (mRNA) Epithelial Ovarian Cancer (PENELOPE) Completed NCT01684878 Phase 3 Gemcitabine (Chemotherapy);Paclitaxel (Chemotherapy);Pertuzumab;Placebo;Topotecan (Chemotherapy)
41 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/ Postoperative Ileus Completed NCT00388479 Phase 3 Alvimopan
42 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00388401 Phase 3 Alvimopan
43 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00388258 Phase 3 Alvimopan
44 Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus Completed NCT00205842 Phase 3 alvimopan
45 Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection? Completed NCT01130675 Phase 3
46 Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery Completed NCT00464425 Phase 3
47 Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus (POI). Completed NCT00401375 Phase 3 Methylnaltrexone;Placebo
48 The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section Completed NCT01131416 Phase 2, Phase 3
49 Early Versus Interval Appendectomy for Ruptured Appendicitis in Children Completed NCT00435032 Phase 3
50 A Study Evaluating IV MOA-728 for the Treatment of POI In Subjects After Ventral Hernia Repair Completed NCT00528970 Phase 3 MOA-728

Search NIH Clinical Center for Intestinal Obstruction

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: intestinal obstruction

Genetic Tests for Intestinal Obstruction

Genetic tests related to Intestinal Obstruction:

# Genetic test Affiliating Genes
1 Intestinal Obstruction 28

Anatomical Context for Intestinal Obstruction

MalaCards organs/tissues related to Intestinal Obstruction:

38
Colon, Small Intestine, Kidney, Liver, Spleen, Lung, Myeloid

Publications for Intestinal Obstruction

Articles related to Intestinal Obstruction:

(show top 50) (show all 750)
# Title Authors Year
1
Time-course evaluation of intestinal structural disorders in a porcine model of intra-abdominal hypertension by mechanical intestinal obstruction. ( 29357386 )
2018
2
Giant granadilla's seeds phytobezoar rectal impactation: a very unusual case of intestinal obstruction. ( 29437811 )
2018
3
Endometrioma of the sigmoid colon presenting with intestinal obstruction. ( 29199174 )
2018
4
Intestinal obstruction caused by a strangulating adnexa: a rare complication of ovarian sparing hysterectomy. ( 29444792 )
2018
5
Caecal duplication cyst: a rare cause of neonatal intestinal obstruction. ( 29326372 )
2018
6
The Turning Point for Morphomechanical Remodeling During Complete Intestinal Obstruction in Rats Occurs After 12-24A h. ( 29427158 )
2018
7
Acute intestinal obstruction due to extrinsic compression by previa myoma and ectopic pregnancy: a case report. ( 29335010 )
2018
8
Hydrocephalus recurrence and intestinal obstruction due to giant CSF pseudocyst. ( 29330586 )
2018
9
A case of canine intestinal obstruction due to ingestion of a superabsorbent polymer bead. ( 29315580 )
2018
10
Sun Should Not Rise and Set on a Case of Acute Intestinal Obstruction. ( 28500588 )
2017
11
A retrospective audit on usage of Diatrizoate Meglumine (Gastrografin(Ar)) for intestinal obstruction or constipation in patients with advanced neoplasms. ( 28805119 )
2017
12
Giant Fecalith Causing Near Intestinal Obstruction and Rectal Ischemia. ( 28611554 )
2017
13
Neonatal intestinal obstruction associated with situs inversus totalis: two case reports and a review of the literature. ( 28918753 )
2017
14
Intestinal Obstruction in a Patient with Sclerosing Encapsulating Peritonitis. ( 28458941 )
2017
15
DYNAMICS OF CHANGES IN INDICES OF ENDOGENOUS INTOXICATION IN PATIENTS WITH ACUTE SMALL INTESTINAL OBSTRUCTION IN CASE OF REAMBERIN USE IN THE COMPREHENSIVE TREATMENT. ( 29328042 )
2017
16
Abdominal cocoon - A rare etiology of intestinal obstruction. ( 29417033 )
2017
17
Intestinal obstruction due to kaposiform hemangioendothelioma in a 1-month-old infant: A case report. ( 28906349 )
2017
18
Laparoscopic resection for Meckel's diverticulum causing intestinal obstruction. ( 28944341 )
2017
19
Isolation of Shewanella putrefaciens in an elderly man with subacute intestinal obstruction & appendicitis. ( 28649508 )
2017
20
Intestinal obstruction caused by appendiceal knot. ( 29196118 )
2017
21
Extensive colorectal lymphomatous polyposis complicated by acute intestinal obstruction: a case report. ( 28705174 )
2017
22
Superior mesenteric artery syndrome: an uncommon cause of intestinal obstruction. ( 28100055 )
2017
23
Anaesthetic management for pheochromocytoma resection in a 5-year-old boy with cerebral haemorrhage and intestinal obstruction. ( 29256547 )
2017
24
Severe intestinal obstruction due to Strongyloides stercoralis in a pregnant woman. ( 28651833 )
2017
25
Large Meckel's Diverticulum and Dilated Adjacent Small Intestine Presenting With Intestinal Obstruction. ( 28899672 )
2017
26
Primary colo-colic invagination as cause of intestinal obstruction. ( 29241869 )
2017
27
Diabetic ketoacidosis by empaglifozin and intestinal obstruction. The importance of arterial blood gas analysis. ( 29196038 )
2017
28
Abdominal Plain Radiograph in Neonatal Intestinal Obstruction. ( 28083492 )
2017
29
Management of a large cystic lymphangioma causing intestinal obstruction. ( 28477401 )
2017
30
Intestinal Obstruction in Early Neonatal Period: A 3-Year Review Of Admitted Cases from a Tertiary Hospital in Ethiopia. ( 29217941 )
2017
31
Peutz-Jeghers syndrome with intermittent upper intestinal obstruction: A case report and review of the literature. ( 28445255 )
2017
32
Distal intestinal obstruction syndrome and colonic pathologies in cystic fibrosis. ( 28067560 )
2017
33
Peritoneal encapsulationA -A an unexpected cause of acute intestinal obstruction. ( 28688775 )
2017
34
Combined use of single-balloon enteroscope and colonoscope for self-expandable metal stent placement in patients with malignant small intestinal obstruction: a single-center comparative clinical observation. ( 28585148 )
2017
35
Kawasaki Disease Presenting as Acute Intestinal Obstruction. ( 28694577 )
2017
36
Predictive factors of management outcome in adult patients with mechanical intestinal obstruction. ( 29355160 )
2017
37
Antenatal Bartter syndrome presenting with vomiting and constipation mimicking subacute intestinal obstruction in a 20-day-old neonate. ( 29141924 )
2017
38
Gastrointestinal Duplication Presenting as Neonatal Intestinal Obstruction: An Experience of 15 Years at Tertiary Care Centre. ( 28083491 )
2017
39
Long-term intestinal obstruction sequelae and growth in children with cystic fibrosis operated for meconium ileus: expectancies and surprises. ( 29224788 )
2017
40
Collagenous colitis presenting with skip lesions mimicking Crohn's disease and complicated by intestinal obstruction. ( 28682012 )
2017
41
Inverted Meckel's Diverticulum: Rare Etiology of an Intestinal Obstruction. ( 29308334 )
2017
42
Effects of herbal medicine Sijunzi decoction on rabbits after relieving intestinal obstruction. ( 28953987 )
2017
43
An Unusual Cause of Intestinal Obstruction in a Young Adult Patient: Inflammatory Fibroid Polyp. ( 28758041 )
2017
44
Postoperative disseminated intravascular coagulation in a pregnant patient with Blue Rubber Bleb Nevus Syndrome presenting with acute intestinal obstruction: Case report and literature review. ( 28858742 )
2017
45
A Rare Case of Bilateral Morgagni's Hernia with Intestinal Obstruction and Malrotation of the Gut in an Adult Patient with Severe Osteogenesis Imperfecta Presenting as Severe Respiratory Distress. ( 28442844 )
2017
46
Meckel's Diverticulum Enterolith: An Extremely Rare Cause of Intestinal Obstruction. ( 28571210 )
2017
47
Intestinal Obstruction by Giant Meckel's Diverticulum. ( 29255748 )
2017
48
Superior mesenteric artery (SMA) syndrome: an unusual cause of intestinal obstruction in palliative care. ( 27506751 )
2016
49
Congenital transmesenteric hernia presenting with intestinal obstruction in an adult: a case report. ( 27459082 )
2016
50
Unusual intestinal obstruction due to idiopathic sclerosing encapsulating peritonitis: a report of two cases and a review. ( 27073795 )
2016

Variations for Intestinal Obstruction

Expression for Intestinal Obstruction

Search GEO for disease gene expression data for Intestinal Obstruction.

Pathways for Intestinal Obstruction

GO Terms for Intestinal Obstruction

Biological processes related to Intestinal Obstruction according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.83 ACHE EDNRB GDNF NRTN RET
2 positive regulation of cell proliferation GO:0008284 9.8 CDX2 EDN3 EDNRB GDNF NOD2
3 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.67 CD8A NRTN RET
4 positive regulation of cell differentiation GO:0045597 9.54 CDX2 EDN3 GDNF
5 response to pain GO:0048265 9.51 EDNRB RET
6 mRNA stabilization GO:0048255 9.48 GDNF MTOR
7 vasoconstriction GO:0042310 9.46 EDN3 EDNRB
8 vein smooth muscle contraction GO:0014826 9.32 EDN3 EDNRB
9 positive regulation of neuron maturation GO:0014042 9.26 MTOR RET
10 posterior midgut development GO:0007497 9.16 EDNRB RET
11 enteric nervous system development GO:0048484 9.13 EDNRB GDNF RET
12 neural crest cell migration GO:0001755 8.92 EDNRB GDNF NRTN RET

Molecular functions related to Intestinal Obstruction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.8 GDNF NRTN RET

Sources for Intestinal Obstruction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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