MCID: INT071
MIFTS: 35

Intestinal Perforation malady

Gastrointestinal diseases category

Aliases & Classifications for Intestinal Perforation

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Intestinal Perforation, Aliases & Descriptions:

Name: Intestinal Perforation 9 11 60
 
Perforation of Intestine 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology9 DOID:2074
ICD9CM27 569.83
NCIt38 C39611
SNOMED-CT55 56905009
MeSH33 D007416
ICD1025 K63.1

Summaries for Intestinal Perforation

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MalaCards based summary: Intestinal Perforation, also known as perforation of intestine, is related to melanoma and peritonitis. An important gene associated with Intestinal Perforation is PTS (6-pyruvoyltetrahydropterin synthase). The compounds pteridine and sepiapterin have been mentioned in the context of this disorder. Affiliated tissues include small intestine, bone and colon, and related mouse phenotype cardiovascular system.

Related Diseases for Intestinal Perforation

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Diseases related to Intestinal Perforation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 121)
idRelated DiseaseScoreTop Affiliating Genes
1melanoma29.3CEACAM3, PTS, NKX2-1, NOS1
2peritonitis10.8
3typhoid fever10.6
4tuberculosis10.4
5polyarteritis nodosa10.4
6perinatal intestinal perforation10.4
7purpura10.4
8miliary tuberculosis10.3
9degos disease10.3
10cytomegalovirus infection10.3
11crohn's disease10.2
12patent ductus arteriosus10.2
13temporal arteritis10.2
14scleroderma10.2
15rheumatoid arthritis10.2
16arthritis10.2
17behcet's disease10.2
18intussusception10.2
19churg-strauss syndrome10.2
20pleomorphic carcinoma10.2
21candidiasis10.2
22ehlers-danlos syndrome10.2
23vaginitis10.2
24fibromatosis10.2
25eosinophilic granulomatosis with polyangiitis10.2
26thymic carcinoma10.1NKX2-1, CEACAM3
27malignant pleural mesothelioma10.1CEACAM3, NKX2-1
28large cell carcinoma10.1CEACAM3, NKX2-1
29medullary thyroid carcinoma, familial10.1NKX2-1, CEACAM3
30thymoma10.1CEACAM3, NKX2-1
31mesothelioma, somatic10.0NKX2-1, CEACAM3
32hyperphenylalaninemia10.0PTS, NOS1
33mesothelioma10.0NKX2-1, CEACAM3
34neuroendocrine tumor10.0CEACAM3, NKX2-1
35paraganglioma and gastric stromal sarcoma10.0
36gastrointestinal stromal tumor10.0
37colorectal cancer10.0
38renal tubular dysgenesis10.0
39myelodysplastic syndrome10.0
40wegener granulomatosis10.0
41hirschsprung disease 110.0
42ehlers-danlos syndrome, type iv10.0
43renal cell carcinoma10.0
44wilms tumor10.0
45hypersensitivity syndrome, carbamazepine-induced10.0
46autoimmune hepatitis10.0
47burns10.0
48cerebral hemorrhage10.0
49gas gangrene10.0
50glomerulonephritis10.0

Graphical network of the top 20 diseases related to Intestinal Perforation:



Diseases related to intestinal perforation

Symptoms for Intestinal Perforation

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Drugs & Therapeutics for Intestinal Perforation

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Drug clinical trials:

Search ClinicalTrials for Intestinal Perforation

Search NIH Clinical Center for Intestinal Perforation

Genetic Tests for Intestinal Perforation

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Anatomical Context for Intestinal Perforation

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MalaCards organs/tissues related to Intestinal Perforation:

31
Small intestine, Bone, Colon, Liver, Lung, Testes, Bone marrow, Breast, Brain, Heart, Kidney, Uterus, Cervix, T cells

Animal Models for Intestinal Perforation or affiliated genes

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MGI Mouse Phenotypes related to Intestinal Perforation:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.6TRPC4AP, NOS1, NKX2-1, PTS

Publications for Intestinal Perforation

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Articles related to Intestinal Perforation:

(show top 50)    (show all 420)
idTitleAuthorsYear
1
Intestinal perforation after radical cystectomy due to drain: case report. (25641456)
2014
2
Fetal intestinal perforation and meconium peritonitis associated with maternal autoimmune hepatitis. (24815708)
2014
3
Trends in the incidence of intestinal perforation in US dialysis patients (1992-2005). (22419235)
2013
4
Intestinal perforation caused by insertion of a nasogastric tube late after gastric bypass. (23382601)
2013
5
Spontaneous intestinal perforation in extremely low birth weight infants: association with indometacin therapy and effects on neurodevelopmental outcomes at 18-22 months corrected age. (22684157)
2013
6
Intestinal perforation after treatment of Burkitt's lymphoma: case report and review of the literature. (23414881)
2013
7
Host factors and typhoid fever-associated intestinal perforation in children in Nigeria. (22648130)
2012
8
Case report: delayed perforation after definitive treatment of focal intestinal perforation with a peritoneal drain. (22966475)
2012
9
Small intestine perforation due to metastatic uterine cervix interdigitating dendritic cell sarcoma: a rare manifestation of a rare disease. (22355501)
2011
10
Intestinal perforation caused by incidental ingestion of a fish bone. Value of CT in the diagnosis. (20883081)
2010
11
Delay in diagnosis and treatment of blunt intestinal perforation does not adversely affect prognosis in the pediatric trauma patient. (20386275)
2010
12
Fasciolopsiasis presenting as intestinal perforation: a case report. (19624087)
2009
13
Enteric fever with suspected intestinal perforation and incidental renal cell carcinoma--a case report. (18416351)
2007
14
New insights into spontaneous intestinal perforation using a national data set: (2) two populations of patients with perforations. (16493433)
2006
15
Spontaneous localized intestinal perforation and intestinal dilatation in very-low-birthweight infants. (17062464)
2006
16
Endometriosis with intestinal perforation in term pregnancy. (16545813)
2006
17
Intestinal perforation and jejunal haemorrhage due to Wegener's granulomatosis. (15789904)
2005
18
Intestinal perforation in Crohn's disease. Factors predictive of surgical resection. (16505755)
2005
19
Peritoneal drainage as definitive management of intestinal perforation in extremely low-birth-weight infants. (14666475)
2003
20
A rare complication of miliary tuberculosis: intestinal perforation. (11301949)
2001
21
Small intestine perforation because of capacitive coupling as a cause of abdominal wall gas gangrene and clostridial sepsis after laparoscopic cholecystectomy. (11147921)
2000
22
Heroin body packing: three fatal cases of intestinal perforation. (10641918)
2000
23
Typhoid intestinal perforation in Nigerian children. (10610606)
1999
24
Intestinal perforation in terminally ill cancer patients: clinical characteristics. (10022672)
1999
25
Neonatal intestinal perforation caused by congenital defect of the small intestinal musculature: report of one case. (10910628)
1999
26
Intestinal perforation after renal transplantation. (9787962)
1998
27
Intestinal perforation by saline total gut lavage in occult diverticulitis. (9826157)
1998
28
Seat belt-induced intestinal perforation. (9115830)
1997
29
Percutaneous peritoneal drainage in the management of acute intestinal perforation. (9069065)
1997
30
Neonatal intestinal perforation caused by intestinal muscularis defect associated with vascular ectasia. (8796760)
1996
31
Intestinal perforation due to an ingested foreign body: laparoscopic management. (8832937)
1996
32
Anaphylactoid purpura with intestinal perforation: report of a case and review of the Japanese literature. (8044297)
1994
33
Intestinal perforation due to Mycobacterium tuberculosis in HIV-infected individuals: report of two cases. (8470647)
1993
34
Small intestinal perforation following minor trauma. (1446940)
1992
35
Intestinal herpes simplex infection presenting with intestinal perforation. (1415108)
1992
36
Localized intestinal perforation following intravenous indomethacin in premature infants. (2732888)
1989
37
Iopamidol in the diagnosis of suspected upper gastro-intestinal perforation. (3568550)
1987
38
Yersinia enterocolitica infection complicated by intestinal perforation. (3307674)
1987
39
Factors affecting mortality in small intestinal perforation. (3781581)
1986
40
Intestinal perforation in typhoid fever: a historical and state-of-the-art review. (3890098)
1985
41
Subcutaneous emphysema. A rare sign of intestinal perforation. (4078791)
1985
42
Small intestinal perforation in Wegener's granulomatosis. (7100026)
1982
43
Intestinal perforation in newborn following intrauterine meconium peritonitis. (450485)
1979
44
Spontaneous neonatal and fetal intestinal perforation. (897945)
1977
45
Intestinal perforation by ascaris. (1194689)
1975
46
URINARY EXCRETION OF GASTROGRAFIN AS A SIGN OF INTESTINAL PERFORATION. (14214170)
1964
47
A sign of intestinal perforation. (14476026)
1962
48
Intestinal perforation and widespread arteritis in rheumatoid arthritis during treatment with cortisone. (13629041)
1959
49
Typhoid fever and intestinal perforation: Recovery with chloromycetin and dihydrostreptomycin. (14796868)
1950
50
Case of Acute Peritonitis following Intestinal Perforation. (20750624)
1883

Variations for Intestinal Perforation

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Expression for genes affiliated with Intestinal Perforation

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Search GEO for disease gene expression data for Intestinal Perforation.

Pathways for genes affiliated with Intestinal Perforation

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Compounds for genes affiliated with Intestinal Perforation

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Sources:
43Novoseek, 24HMDB, 12DrugBank, 28IUPHAR
See all sources

Compounds related to Intestinal Perforation according to GeneCards Suite gene sharing:

(show all 15)
idCompoundScoreTop Affiliating Genes
1pteridine439.8NOS1, PTS
2sepiapterin43 2410.8NOS1, PTS
3pterin43 2410.8NOS1, PTS
4tetrahydrobiopterin43 24 1211.8PTS, NOS1
5cgmp43 2810.6NOS1, PTS
6formaldehyde43 2410.5NOS1, NKX2-1
7mucicarmine439.5NKX2-1, CEACAM3
8b 723439.4NKX2-1, CEACAM3
9hematoxylin439.4NKX2-1, CEACAM3
10carbon439.1NOS1, CEACAM3
11steroid438.9PTS, CEACAM3, NKX2-1
12aspartate438.9NOS1, CEACAM3, PTS
13nitric oxide43 24 1210.8NOS1, CEACAM3, PTS
14oxygen43 249.6PTS, CEACAM3, NOS1
15estrogen438.4NOS1, NKX2-1, CEACAM3

GO Terms for genes affiliated with Intestinal Perforation

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Products for genes affiliated with Intestinal Perforation

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Intestinal Perforation

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet