MCID: INT071
MIFTS: 32

Intestinal Perforation malady

Gastrointestinal category

Summaries for Intestinal Perforation

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64Wikipedia, 33MalaCards
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Wikipedia:64 Gastrointestinal perforation is a complete penetration of any part of the wall of the gastrointestinal... more...

MalaCards: Intestinal Perforation, also known as perforation of intestine, is related to typhoid fever and intestinal tuberculosis. An important gene associated with Intestinal Perforation is PTS (6-pyruvoyltetrahydropterin synthase). The compounds pteridine and sepiapterin have been mentioned in the context of this disorder.

Aliases & Classifications for Intestinal Perforation

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 35MeSH, 40NCIt, 57SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal


Aliases & Descriptions:

intestinal perforation 8 10 61
perforation of intestine 8


External Ids:

Disease Ontology8 DOID:2074
MeSH35 D007416
NCIt40 C39611
SNOMED-CT57 56905009
ICD9CM27 569.83
ICD1025 K63.1

Related Diseases for Intestinal Perforation

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Intestinal Perforation:



Diseases related to intestinal perforation

Clinical Features for Intestinal Perforation

Drugs & Therapeutics for Intestinal Perforation

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Intestinal Perforation

Anatomical Context for Intestinal Perforation

Animal Models for Intestinal Perforation or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Intestinal Perforation

Sources:
51PubMed
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Articles related to Intestinal Perforation:

(show top 50)    (show all 419)
idTitleAuthorsYear
1
Multiple intestinal strictures with perforation in a patient under antitubercular treatment for abdominal tuberculosis. (23787535)
2013
2
Intestinal perforation after treatment of Burkitt's lymphoma: case report and review of the literature. (23414881)
2013
3
Intestinal perforation in the immediate puerperium: A rare complication of bariatric surgery. (23971668)
2013
4
Brain Magnetic Resonance Imaging in Infants with Surgical Necrotizing Enterocolitis or Spontaneous Intestinal Perforation versus Medical Necrotizing Enterocolitis. (24210927)
2013
5
Functional impairments at school age of children with necrotizing enterocolitis or spontaneous intestinal perforation. (21857378)
2011
6
Decorative crystal balls causing intestinal perforation. (21897572)
2011
7
Megacystis microcolon intestinal hypoperistalsis syndrome complicated by perforation. (21478590)
2011
8
Cholecystocolonic fistula prevents upper intestinal obstruction by a large gallstone after perforation into the duodenum. (19526247)
2010
9
Prenatal or postnatal indomethacin exposure and neonatal gut injury associated with isolated intestinal perforation and necrotizing enterocolitis. (20410905)
2010
10
Typhoid intestinal disease: 32 perforations in 1 patient. (18408786)
2008
11
Pattern of presentation and management of typhoid intestinal perforation in Sagamu, South-West Nigeria: a 15 year study. (19048751)
2008
12
Diagnosing intestinal perforation: a new approach. (18437642)
2008
13
Maternal factors in extremely low birth weight infants who develop spontaneous intestinal perforation. (17998314)
2007
14
Focal intestinal perforation in extremely-low-birth-weight neonates: etiological consideration from histological findings. (17653555)
2007
15
The role of laparotomy for intestinal perforation in very low birth weight infants. (16952585)
2006
16
Intestinal perforation and jejunal haemorrhage due to Wegener's granulomatosis. (15789904)
2005
17
Intestinal perforation as a long-term complication of plug and mesh inguinal hernioplasty: case report. (15290610)
2005
18
Renal tubular dysgenesis and multiple intestinal perforation. (12447649)
2003
19
A rare complication of miliary tuberculosis: intestinal perforation. (11301949)
2001
20
Rare complication of intestinal volvulus with perforation of the small bowel secondary to the peritoneal end of the ventriculoperitoneal shunt (VPS). (11315306)
2001
21
Intestinal perforation secondary to Salmonella typhi: case report and review of the literature. (10695758)
2000
22
Intestinal perforation--a unique cause. (11016184)
2000
23
Intestinal perforation by saline total gut lavage in occult diverticulitis. (9826157)
1998
24
A patient with acquired immunodeficiency syndrome and untreated Encephalitozoon (Septata) intestinalis microsporidiosis leading to small bowel perforation. Response to albendazole. (9278619)
1997
25
Solitary intestinal fibromatosis: a rare cause of intestinal perforation in neonates. (9244122)
1997
26
Intestinal perforation 14 years after abdominal irradiation and chemotherapy for Wilms tumor. (8846136)
1996
27
Case report: intestinal perforation--an unusual complication of endoscopic biliary stenting. (7533042)
1994
28
Intestinal perforation from gastrointestinal histoplasmosis in acquired immunodeficiency syndrome. Case report and review of the literature. (8457161)
1993
29
Intestinal perforation as an initial presentation of polyarteritis nodosa in an 8-year-old boy. (8097768)
1993
30
A rare case of perineal pain: intestinal perforation caused by a press-through package. (1510270)
1992
31
Spontaneous focal intestinal perforation in prematurity: report of three cases. (2637614)
1989
32
Intestinal perforation caused by larval Eustrongylides (Nematoda: Dioctophymatoidae) in New Jersey. (2742040)
1989
33
Ascaris lumbricoides and intestinal perforation. (3304524)
1987
34
Intestinal perforation due to blunt trauma in children in an era of increased nonoperative treatment. (3701896)
1986
35
Localized intestinal perforation after intravenous indomethacin in a premature infant. (3818330)
1986
36
Intestinal perforation associated with osmotic slow release indomethacin capsules. (6416544)
1983
37
The effect of experimentally induced intestinal perforation at an early developmental stage. (7338753)
1981
38
Intestinal perforation in ascariasis--case reports. (473306)
1979
39
Emphysema of the leg as a presenting sign of large-intestinal perforation: report of two cases. (844399)
1977
40
Small intestinal perforation due to secondaries from Bronchogenic carcinoma. (952722)
1976
41
Intestinal perforation by ascaris. (1194689)
1975
42
Nonsurgical treatment of intestinal perforation due to peritoneal dialysis. (4682261)
1973
43
Prenatal intestinal perforation associated with meconium pseudocyst and ileal angiomatous malformation. (4635529)
1972
44
Ischemic intestinal perforation in newborns. Management of multiple ileal perforations following intrapartum shock. (5545907)
1971
45
Alkaline phosphatase in intestinal perforation. (5818496)
1969
46
Intestinal perforation, exchange transfusion, and P.V.C. (4188387)
1969
47
Experience with a urine precipitation test for intestinal perforation. (5651227)
1968
48
Intestinal perforation complicating typhoid fever in children. (18866963)
1948
49
Intestinal perforation and rupture of the gallbladder in children with typhoid. (18123748)
1948
50
Primary Intestinal Tuberculosis in Children: Perforation of Ulcers. (20761558)
1904

Genetic Variations for Intestinal Perforation

Expression for genes affiliated with Intestinal Perforation

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Intestinal Perforation

Search GEO for disease gene expression data for Intestinal Perforation.

Pathways for genes affiliated with Intestinal Perforation

Compounds for genes affiliated with Intestinal Perforation

Sources:
45Novoseek, 24HMDB, 11DrugBank
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Compounds related to Intestinal Perforation according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pteridine459.8NOS1, PTS
2sepiapterin45 2410.8NOS1, PTS
3pterin45 2410.8NOS1, PTS
4tetrahydrobiopterin45 11 2411.6NOS1, PTS
5mucicarmine459.5NKX2-1, CEACAM3
6b 723459.3NKX2-1, CEACAM3
7hematoxylin459.1NKX2-1, CEACAM3
8aspartate459.0NOS1, PTS, CEACAM3

GO Terms for genes affiliated with Intestinal Perforation

Products for genes affiliated with Intestinal Perforation

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Intestinal Perforation

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet