MCID: INT046
MIFTS: 47

Intestinal Tuberculosis malady

Infectious diseases, Gastrointestinal diseases categories
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Summaries for Intestinal Tuberculosis

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Disease Ontology:8 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. the infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary: Intestinal Tuberculosis, also known as tuberculosis of intestine, is related to tuberculosis and crohn's disease, and has symptoms including An important gene associated with Intestinal Tuberculosis is ADA (adenosine deaminase), and among its related pathways are Purine metabolism and Purine metabolism. The compounds aspirin and alpha,beta-methyleneadenosine-5-diphosphate have been mentioned in the context of this disorder. Affiliated tissues include intestine, liver and colon, and related mouse phenotypes are renal/urinary system and hematopoietic system.

Aliases & Classifications for Intestinal Tuberculosis

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Intestinal Tuberculosis, Aliases & Descriptions:

Name: Intestinal Tuberculosis 8 10
Tuberculosis of Intestine 8 62
 
Tuberculosis of Intestines 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology8 DOID:13282
ICD9CM27 014.8

Related Diseases for Intestinal Tuberculosis

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Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to intestinal tuberculosis

Symptoms for Intestinal Tuberculosis

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Drugs & Therapeutics for Intestinal Tuberculosis

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Drug clinical trials:

Search ClinicalTrials for Intestinal Tuberculosis

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

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Anatomical Context for Intestinal Tuberculosis

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MalaCards organs/tissues related to Intestinal Tuberculosis:

32
Liver, Colon, Testes, Small intestine, Heart, Kidney, Pancreas, Appendix

FMA organs/tissues related to Intestinal Tuberculosis:

14
Intestine

Animal Models for Intestinal Tuberculosis or affiliated genes

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MGI Mouse Phenotypes related to Intestinal Tuberculosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6ACE, NT5E, ADA
2MP:00053977.8ACE, NT5E, PSMB9, ADA

Publications for Intestinal Tuberculosis

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Articles related to Intestinal Tuberculosis:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Differentiation of Crohn's disease from intestinal tuberculosis by clinical and CT enterographic models. (24694791)
2014
2
The utility of platelet, mean platelet volume, and red cell distribution width in the diagnosis of active Crohn's disease and intestinal tuberculosis. (24252895)
2013
3
Effectiveness of interferon-gamma release assays for differentiating intestinal tuberculosis from Crohn's disease: A meta-analysis. (24307809)
2013
4
Intestinal Tuberculosis Sometimes Mimics Crohn`s Disease. (24390954)
2013
5
Intestinal tuberculosis. (24269176)
2013
6
Severe pulmonary tuberculosis complicating intestinal tuberculosis with the entire colorectal ulcers. (24043012)
2013
7
Diagnostic sensitivity of culture and drug resistance patterns in Korean patients with intestinal tuberculosis. (22508109)
2012
8
Intestinal tuberculosis complicated with perforation during anti-tuberculous treatment in a 13-year-old girl with defective mitogen-induced IL-12 production. (22841619)
2012
9
Case of intestinal tuberculosis mimicking Crohn's disease. (23569489)
2012
10
Prospective randomized trial of six-month versus nine-month therapy for intestinal tuberculosis. (19667282)
2009
11
Diagnostic challenges of intestinal tuberculosis in a patient with chronic diarrhoea: case report. (18557255)
2008
12
Chronic inflammatory demyelinating polyneuropathy associated with intestinal tuberculosis. (17712474)
2007
13
Intestinal tuberculosis mimicking Crohn's disease. (17976805)
2007
14
Anti-Saccharomyces cerevisiae antibody does not differentiate between Crohn's disease and intestinal tuberculosis. (17160471)
2007
15
Intestinal tuberculosis and secondary liver abscess. (17117317)
2006
16
PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis. (16672431)
2006
17
Selective jejunal artery pseudoaneurysm embolization in a patient with massive gastrointestinal bleeding due to intestinal tuberculosis. (17046480)
2006
18
Tuberculous peritonitis developing during chemotherapy for pulmonary and intestinal tuberculosis: a case report. (15823196)
2005
19
Imaging findings of intestinal tuberculosis. (15665681)
2005
20
Tissue polymerase chain reaction in diagnosis of intestinal tuberculosis and Crohn's disease. (15906835)
2004
21
Mesenteric artery aneurysms in intestinal tuberculosis as a cause of lower gastrointestinal bleeding. (11178687)
2001
22
A rare case of intestinal tuberculosis in a child. (10484899)
1999
23
Colonofiberscopic diagnosis of intestinal tuberculosis. (9481060)
1998
24
Radiological evaluation of complications of intestinal tuberculosis. (9587753)
1998
25
Retained surgical sponge simulating intestinal tuberculosis. (9114579)
1997
26
Mesenteric vasculopathy in intestinal tuberculosis. (9357183)
1997
27
Inguinal hernia incarceration as a form of intestinal tuberculosis. (8984586)
1996
28
Hyperaggregation of platelets in intestinal tuberculosis: role of platelets in chronic inflammation. (7832193)
1995
29
Value of polymerase chain reaction assay in diagnosis of intestinal tuberculosis and differentiation from Crohn's disease. (7796630)
1995
30
Gallstone disease and lithogenicity of bile in intestinal tuberculosis. (7129559)
1982
31
Primary intestinal tuberculosis following renal transplantation. (7050752)
1982
32
Ileal chloride secretion as a cause of secretory diarrhea in a patient with primary intestinal tuberculosis. (422011)
1979
33
Intestinal tuberculosis: experience at a Canadian teaching institution. (930948)
1977
34
Intestinal tuberculosis. (1052456)
1976
35
Intestinal tuberculosis. (814320)
1975
36
Intestinal tuberculosis with fistula in ano. (5964303)
1966
37
The clinical picture and rare variants of primary gastro-intestinal tuberculosis. (13946985)
1963
38
The prognosis of bilateral symmetrical diffuse nodular pulmonary tuberculosis and its possible relationship to intestinal tuberculosis. (13317783)
1956
39
Changes in the pulse rate of intestinal tuberculosis patients by abdominal pressure. (13164003)
1954
40
Primary intestinal tuberculosis. (14931789)
1952
41
A study of the pulmonary tuberculous patients complicated with intestinal tuberculosis, particularly on the blood and the indican-quantity in the urine; III. A comparison of the indican-quantities on the urine between two groups, the pulmonary tuberculous patients complicated with and without intestinal tuberculosis. (14958414)
1952
42
A study on diagnosis and symptoms of secondary intestinal tuberculosis, compared with roentgenographic findings. (13064633)
1952
43
The late results of paraaminosalicylic acid therapy in secondary intestinal tuberculosis. (13007528)
1952
44
Chemotherapy as prophylaxis against secondary intestinal tuberculosis; a report of 150 autopsies. (14885673)
1951
45
Para-aminosalicylic acid therapy in intestinal tuberculosis. (15410994)
1950
46
Surgical complications of intestinal tuberculosis as seen at necropsy. (18908959)
1948
47
Cicatrizing intestinal tuberculosis and regional enteritis. (18906536)
1947
48
Intestinal tuberculosis; some observations. (20247443)
1947
49
Intestinal Tuberculosis. (20322135)
1941
50
THE CURABILITY OF INTESTINAL TUBERCULOSIS. (20316434)
1927

Variations for Intestinal Tuberculosis

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Expression for genes affiliated with Intestinal Tuberculosis

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Expression patterns in normal tissues for genes affiliated with Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for genes affiliated with Intestinal Tuberculosis

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Pathways related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
UTP and CTP dephosphorylation II37
ATP ITP metabolism60
purine deoxyribonucleosides salvage37
9.2NT5E, ADA
2
Show member pathways
purine deoxyribonucleosides degradation37
purine nucleotides degradation37
adenine and adenosine salvage II37
adenine and adenosine salvage III37
oxidized GTP and dGTP detoxification37
urate biosynthesis/inosine 5-phosphate degradation37
adenine and adenosine salvage I37
purine ribonucleosides degradation to ribose-1-phosphate37
inosine-5-phosphate biosynthesis37
guanosine nucleotides degradation37
guanine and guanosine salvage37
adenosine nucleotides degradation37
5-aminoimidazole ribonucleotide biosynthesis37
9.2NT5E, ADA
3
Show member pathways
One Carbon Metabolism37
dTMP de novo biosynthesis (mitochondrial)37
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate37
Trans-sulfuration and one carbon metabolism37
methionine salvage37
Methionine metabolism60
9.2NT5E, ADA

Compounds for genes affiliated with Intestinal Tuberculosis

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Sources:
44Novoseek, 50PharmGKB, 28IUPHAR, 24HMDB, 11DrugBank
See all sources

Compounds related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1aspirin44 50 28 2412.4ACE, ADA
2alpha,beta-methyleneadenosine-5-diphosphate449.4NT5E, ADA
3purine nucleoside449.3NT5E, ADA
4xanthine44 2410.3NT5E, ADA
5pyrimidine44 2410.3NT5E, ADA
6purine44 2410.2ADA, NT5E
7nucleoside449.1NT5E, ADA
8cytarabine44 50 1110.9NT5E, ADA

GO Terms for genes affiliated with Intestinal Tuberculosis

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Cellular components related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1ADA, ACE
2plasma membraneGO:0058868.1CD53, ACE, NT5E, ADA
3extracellular vesicular exosomeGO:0700627.9CD53, ACE, NT5E, PSMB9

Biological processes related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1purine nucleobase metabolic processGO:0061449.2NT5E, ADA
2negative regulation of inflammatory responseGO:0507289.1NT5E, ADA
3nucleobase-containing small molecule metabolic processGO:0550868.9NT5E, ADA
4small molecule metabolic processGO:0442818.7NT5E, PSMB9, ADA

Products for genes affiliated with Intestinal Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Intestinal Tuberculosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet