MCID: INT046
MIFTS: 46

Intestinal Tuberculosis malady

Gastrointestinal diseases, Infectious diseases categories

Summaries for Intestinal Tuberculosis

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Sources:
9Disease Ontology, 34MalaCards
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Disease Ontology:9 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. the infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards: Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to tuberculosis and crohn's disease, and has symptoms including vomiting, nausea and gastrointestinal bleeding. An important gene associated with Intestinal Tuberculosis is ADA (adenosine deaminase), and among its related pathways are Purine metabolism and Purine metabolism. The compounds aspirin and alpha,beta-methyleneadenosine-5-diphosphate have been mentioned in the context of this disorder. Affiliated tissues include intestine, testes and liver, and related mouse phenotypes are renal/urinary system and hematopoietic system.

Aliases & Classifications for Intestinal Tuberculosis

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 28ICD9CM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

intestinal tuberculosis 9 11
tuberculosis of intestines 63
tuberculosis of intestine 9


External Ids:

Disease Ontology9 DOID:13282
ICD9CM28 014.8

Related Diseases for Intestinal Tuberculosis

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to intestinal tuberculosis

Symptoms for Intestinal Tuberculosis

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Sources:
9Disease Ontology
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Symptoms:

9
  • vomiting
  • nausea
  • gastrointestinal bleeding
  • abdominal pain

Drugs & Therapeutics for Intestinal Tuberculosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Intestinal Tuberculosis

Drug clinical trials:

Search ClinicalTrials for Intestinal Tuberculosis

Search NIH Clinical Center for Intestinal Tuberculosis

Search CenterWatch for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

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Anatomical Context for Intestinal Tuberculosis

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Sources:
34MalaCards, 15FMA
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MalaCards organs/tissues related to Intestinal Tuberculosis:

34
Testes, Liver, Colon, Appendix, Small intestine, Heart

FMA organs/tissues related to Intestinal Tuberculosis:

15
Intestine

Animal Models for Intestinal Tuberculosis or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Intestinal Tuberculosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6ACE, NT5E, ADA
2MP:00053977.8ACE, NT5E, PSMB9, ADA

Publications for Intestinal Tuberculosis

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Sources:
53PubMed
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Articles related to Intestinal Tuberculosis:

(show top 50)    (show all 227)
idTitleAuthorsYear
1
The utility of platelet, mean platelet volume, and red cell distribution width in the diagnosis of active Crohn's disease and intestinal tuberculosis. (24252895)
2013
2
Effectiveness of interferon-gamma release assays for differentiating intestinal tuberculosis from Crohn's disease: A meta-analysis. (24307809)
2013
3
Intestinal Tuberculosis Sometimes Mimics Crohn`s Disease. (24390954)
2013
4
Intestinal tuberculosis. (24269176)
2013
5
Severe pulmonary tuberculosis complicating intestinal tuberculosis with the entire colorectal ulcers. (24043012)
2013
6
Diagnostic sensitivity of culture and drug resistance patterns in Korean patients with intestinal tuberculosis. (22508109)
2012
7
Intestinal tuberculosis complicated with perforation during anti-tuberculous treatment in a 13-year-old girl with defective mitogen-induced IL-12 production. (22841619)
2012
8
Case of intestinal tuberculosis mimicking Crohn's disease. (23569489)
2012
9
Prospective randomized trial of six-month versus nine-month therapy for intestinal tuberculosis. (19667282)
2009
10
Diagnostic challenges of intestinal tuberculosis in a patient with chronic diarrhoea: case report. (18557255)
2008
11
Chronic inflammatory demyelinating polyneuropathy associated with intestinal tuberculosis. (17712474)
2007
12
Intestinal tuberculosis mimicking Crohn's disease. (17976805)
2007
13
Anti-Saccharomyces cerevisiae antibody does not differentiate between Crohn's disease and intestinal tuberculosis. (17160471)
2007
14
Intestinal tuberculosis and secondary liver abscess. (17117317)
2006
15
PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis. (16672431)
2006
16
Selective jejunal artery pseudoaneurysm embolization in a patient with massive gastrointestinal bleeding due to intestinal tuberculosis. (17046480)
2006
17
Tuberculous peritonitis developing during chemotherapy for pulmonary and intestinal tuberculosis: a case report. (15823196)
2005
18
Imaging findings of intestinal tuberculosis. (15665681)
2005
19
Tissue polymerase chain reaction in diagnosis of intestinal tuberculosis and Crohn's disease. (15906835)
2004
20
Mesenteric artery aneurysms in intestinal tuberculosis as a cause of lower gastrointestinal bleeding. (11178687)
2001
21
A rare case of intestinal tuberculosis in a child. (10484899)
1999
22
Colonofiberscopic diagnosis of intestinal tuberculosis. (9481060)
1998
23
Radiological evaluation of complications of intestinal tuberculosis. (9587753)
1998
24
Retained surgical sponge simulating intestinal tuberculosis. (9114579)
1997
25
Mesenteric vasculopathy in intestinal tuberculosis. (9357183)
1997
26
Inguinal hernia incarceration as a form of intestinal tuberculosis. (8984586)
1996
27
Hyperaggregation of platelets in intestinal tuberculosis: role of platelets in chronic inflammation. (7832193)
1995
28
Value of polymerase chain reaction assay in diagnosis of intestinal tuberculosis and differentiation from Crohn's disease. (7796630)
1995
29
Gallstone disease and lithogenicity of bile in intestinal tuberculosis. (7129559)
1982
30
Primary intestinal tuberculosis following renal transplantation. (7050752)
1982
31
Ileal chloride secretion as a cause of secretory diarrhea in a patient with primary intestinal tuberculosis. (422011)
1979
32
Intestinal tuberculosis: experience at a Canadian teaching institution. (930948)
1977
33
Intestinal tuberculosis. (1052456)
1976
34
Intestinal tuberculosis. (814320)
1975
35
Intestinal tuberculosis with fistula in ano. (5964303)
1966
36
The clinical picture and rare variants of primary gastro-intestinal tuberculosis. (13946985)
1963
37
The prognosis of bilateral symmetrical diffuse nodular pulmonary tuberculosis and its possible relationship to intestinal tuberculosis. (13317783)
1956
38
Changes in the pulse rate of intestinal tuberculosis patients by abdominal pressure. (13164003)
1954
39
Primary intestinal tuberculosis. (14931789)
1952
40
A study of the pulmonary tuberculous patients complicated with intestinal tuberculosis, particularly on the blood and the indican-quantity in the urine; III. A comparison of the indican-quantities on the urine between two groups, the pulmonary tuberculous patients complicated with and without intestinal tuberculosis. (14958414)
1952
41
A study on diagnosis and symptoms of secondary intestinal tuberculosis, compared with roentgenographic findings. (13064633)
1952
42
The late results of paraaminosalicylic acid therapy in secondary intestinal tuberculosis. (13007528)
1952
43
Chemotherapy as prophylaxis against secondary intestinal tuberculosis; a report of 150 autopsies. (14885673)
1951
44
Para-aminosalicylic acid therapy in intestinal tuberculosis. (15410994)
1950
45
Surgical complications of intestinal tuberculosis as seen at necropsy. (18908959)
1948
46
Cicatrizing intestinal tuberculosis and regional enteritis. (18906536)
1947
47
Intestinal tuberculosis; some observations. (20247443)
1947
48
Intestinal tuberculosis. (20271137)
1947
49
Intestinal Tuberculosis. (20322135)
1941
50
THE CURABILITY OF INTESTINAL TUBERCULOSIS. (20316434)
1927

Variations for Intestinal Tuberculosis

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Expression for genes affiliated with Intestinal Tuberculosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for genes affiliated with Intestinal Tuberculosis

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Sources:
51PathCards, 56Reactome, 39NCBI BioSystems Database, 61Thomson Reuters, 31KEGG, 52PharmGKB
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Pathways related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
UTP and CTP dephosphorylation II39
ATP ITP metabolism61
purine deoxyribonucleosides salvage39
9.2NT5E, ADA
2
Show member pathways
purine deoxyribonucleosides degradation39
purine nucleotides degradation39
adenine and adenosine salvage II39
adenine and adenosine salvage III39
oxidized GTP and dGTP detoxification39
urate biosynthesis/inosine 5-phosphate degradation39
adenine and adenosine salvage I39
purine ribonucleosides degradation to ribose-1-phosphate39
inosine-5-phosphate biosynthesis39
guanosine nucleotides degradation39
guanine and guanosine salvage39
adenosine nucleotides degradation39
5-aminoimidazole ribonucleotide biosynthesis39
9.2NT5E, ADA
3
Show member pathways
One Carbon Metabolism39
dTMP de novo biosynthesis (mitochondrial)39
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate39
Trans-sulfuration and one carbon metabolism39
methionine salvage39
Methionine metabolism61
9.2NT5E, ADA

Compounds for genes affiliated with Intestinal Tuberculosis

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Sources:
46Novoseek, 52PharmGKB, 30IUPHAR, 25HMDB, 12DrugBank
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Compounds related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1aspirin46 52 30 2512.4ACE, ADA
2alpha,beta-methyleneadenosine-5-diphosphate469.4NT5E, ADA
3purine nucleoside469.3NT5E, ADA
4xanthine46 2510.3NT5E, ADA
5pyrimidine46 2510.3NT5E, ADA
6purine46 2510.2ADA, NT5E
7nucleoside469.1NT5E, ADA
8cytarabine46 52 1210.9NT5E, ADA

GO Terms for genes affiliated with Intestinal Tuberculosis

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Sources:
17Gene Ontology
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Cellular components related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1ADA, ACE
2plasma membraneGO:0058868.1CD53, ACE, NT5E, ADA
3extracellular vesicular exosomeGO:0700627.9CD53, ACE, NT5E, PSMB9

Biological processes related to Intestinal Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1purine nucleobase metabolic processGO:0061449.2NT5E, ADA
2negative regulation of inflammatory responseGO:0507289.1NT5E, ADA
3nucleobase-containing small molecule metabolic processGO:0550868.9NT5E, ADA
4small molecule metabolic processGO:0442818.7NT5E, PSMB9, ADA

Products for genes affiliated with Intestinal Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Intestinal Tuberculosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet