MCID: INT046
MIFTS: 37

Intestinal Tuberculosis malady

Categories: Infectious diseases, Gastrointestinal diseases

Aliases & Classifications for Intestinal Tuberculosis

Aliases & Descriptions for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 14
Tuberculosis of Intestines 69
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 35 014.8
UMLS 69 C0152724

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and tuberculosis, and has symptoms including abdominal pain, gastrointestinal bleeding and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto). The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and testes, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Intestinal Tuberculosis

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • abdominal pain
  • gastrointestinal bleeding
  • nausea
  • vomiting

MGI Mouse Phenotypes related to Intestinal Tuberculosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.35 ABCA3 ABCB8 CRP LOXL2 NT5E
2 homeostasis/metabolism MP:0005376 9.02 ABCA3 ABCB8 CRP LOXL2 NT5E

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 44)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 4
2 Cola Nutraceutical Phase 4
3
Meloxicam Approved, Vet_approved Phase 3 71125-38-7 5281106 54677470
4
Adalimumab Approved Phase 3,Phase 1,Phase 2 331731-18-1 16219006
5 Analgesics Phase 3,Phase 2
6 Analgesics, Non-Narcotic Phase 3,Phase 2
7 Anti-Inflammatory Agents Phase 3,Phase 2,Phase 1
8 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 2
9 Antirheumatic Agents Phase 3,Phase 2,Phase 1
10 Cyclooxygenase 2 Inhibitors Phase 3
11 Cyclooxygenase Inhibitors Phase 3,Phase 2
12 Peripheral Nervous System Agents Phase 3,Phase 2
13 Antitubercular Agents Phase 3
14 Antibodies Phase 3
15 Antibodies, Monoclonal Phase 3
16 Immunoglobulins Phase 3
17
Aspirin Approved, Vet_approved Phase 2 50-78-2 2244
18
Infliximab Approved Phase 1, Phase 2 170277-31-3
19
Vorinostat Approved, Investigational Phase 1, Phase 2 149647-78-9 5311
20 Antipyretics Phase 2
21 Fibrinolytic Agents Phase 2
22 Platelet Aggregation Inhibitors Phase 2
23 Dermatologic Agents Phase 1, Phase 2
24 Gastrointestinal Agents Phase 1, Phase 2
25 Histone Deacetylase Inhibitors Phase 1, Phase 2
26
Xylometazoline Approved Phase 1 526-36-3 5709
27 Interleukin-12 Phase 1
28
Albendazole Approved, Vet_approved 54965-21-8 2082
29
Rifampin Approved 13292-46-1 5458213 5381226
30
Certolizumab pegol Approved 428863-50-7
31 Anthelmintics
32 Anti-Infective Agents
33 Antimitotic Agents
34 Antiparasitic Agents
35 Antiprotozoal Agents
36 Anti-Bacterial Agents
37 Antibiotics, Antitubercular
38 Cytochrome P-450 CYP3A Inducers
39 Nucleic Acid Synthesis Inhibitors
40 rifamycin SV
41 Rifamycins
42 Interferon-gamma
43 interferons
44 Immunosuppressive Agents

Interventional clinical trials:

(show all 25)
id Name Status NCT ID Phase
1 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914 Phase 4
2 TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial Unknown status NCT02060006 Phase 3
3 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3
4 Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease Completed NCT00195715 Phase 3
5 A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis Completed NCT02237365 Phase 2
6 Safety and Tolerability of Vorinostat for the Treatment of Moderate-to-Severe Crohn s Disease Recruiting NCT03167437 Phase 1, Phase 2
7 Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease Terminated NCT00325078 Phase 1, Phase 2
8 STA-5326 Meslylate to Treat Gut Inflammation Associated With Common Variable Immunodeficiency Completed NCT00263237 Phase 1
9 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
10 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
11 The Effect of Parasitic Worm Infections on the Immune Response to Tuberculosis Bacteria Completed NCT00342017
12 Deworming Against Tuberculosis Completed NCT00857116
13 Epidemiology of H. Pylori Transmission Completed NCT02740140
14 Study of Patients With Strongyloides Stercoralis Infection Completed NCT00001245
15 Immune Activation and Drug Absorption in HIV-Infected Patients Completed NCT01845298
16 Pilot Survey of Dengue Fever in Solomon Islands Completed NCT01868399
17 Treatment of Helminth co-Infection: Short-Term Effects on HIV-1 Progression Markers and Immune Activation Completed NCT00130910
18 Remicade Safety Line (Crohn's Disease)(Study P03288)(COMPLETED) Completed NCT00818272
19 Surveillance of Humira Injection in Korean Patients Completed NCT01083121
20 MRI Differentiating Gut TB and Crohn's Recruiting NCT03096379
21 Effect of Filarial Infection on Immune Responses in Latent Tuberculosis Recruiting NCT01547884
22 The Role of IGRA in Screening and Monitoring for TB During Anti TNF Therapy in Patients With IMID Active, not recruiting NCT02135289
23 Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy Active, not recruiting NCT00286767
24 Parasitic Infections of the Gastrointestinal Tract Terminated NCT00001162
25 Certolizumab Pegol for the Treatment of Patients With Active Rheumatoid Arthritis (RA) and Crohn's Disease (CD) Terminated NCT01577264

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

MalaCards organs/tissues related to Intestinal Tuberculosis:

39
Liver, Colon, Testes, Small Intestine, Heart, Kidney, Appendix

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

18
Intestine

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 280)
id Title Authors Year
1
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
2
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
3
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
4
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
5
Primary Enterolith in a Patient with Intestinal Tuberculosis: A Case Report. ( 27853338 )
2016
6
Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans. ( 27296940 )
2016
7
Development and validation of visceral fat quantification as a surrogate marker for differentiation of Crohn's disease and Intestinal tuberculosis. ( 27532624 )
2016
8
An Analysis of the Clinical, Endoscopic, and Pathologic Features of Intestinal Tuberculosis. ( 26974755 )
2016
9
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016
10
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016
11
Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. ( 27557645 )
2016
12
Differences in Clinical Manifestations according to the Positivity of Interferon-I^ Assay in Patients with Intestinal Tuberculosis. ( 27282272 )
2016
13
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
14
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
15
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2016
16
Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 27997555 )
2016
17
Clinical and Laboratory Diagnosis of Intestinal Tuberculosis. ( 27231171 )
2016
18
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
19
Computerized tomography-based predictive model for differentiation of Crohn's disease from intestinal tuberculosis. ( 25966870 )
2015
20
Computed tomographic enterography adds value to colonoscopy in differentiating Crohn's disease from intestinal tuberculosis: a potential diagnostic algorithm. ( 25675175 )
2015
21
Genome-wide gene expression analysis for target genes to differentiate patients with intestinal tuberculosis and Crohn's disease and discriminative value of FOXP3 mRNA expression. ( 25969456 )
2015
22
Multiple, Pan-Enteric Perforation Secondary to Intestinal Tuberculosis. ( 26798540 )
2015
23
Extraintestinal manifestations of inflammatory bowel disease and intestinal tuberculosis: Frequency and relation with disease phenotype. ( 25663290 )
2015
24
P285. A novel scoring system for differential diagnosis between Crohn's disease and intestinal tuberculosis: A prospective study. ( 25717761 )
2015
25
High faecal calprotectin levels in intestinal tuberculosis are associated with granulomas in intestinal biopsies. ( 25522183 )
2015
26
Differences in clinical features of Crohn's disease and intestinal tuberculosis. ( 25834333 )
2015
27
Subcutaneous abscess at epidural catheter insertion site in a patient with intestinal tuberculosis. ( 26111664 )
2015
28
The features of intestinal tuberculosis by contrast-enhanced ultrasound. ( 26173398 )
2015
29
Differential diagnosis between Crohn's disease and intestinal tuberculosis using integrated parameters including clinical manifestations, T-SPOT, endoscopy and CT enterography. ( 26770348 )
2015
30
Evaluation of intestinal tuberculosis by multi-slice computed tomography enterography. ( 26695641 )
2015
31
Combined identifying granuloma and biopsy culture is useful for diagnosing intestinal tuberculosis. ( 25868516 )
2015
32
P139. Predictive Factors for Differentiating between Crohn's disease and Intestinal tuberculosis in Korea. ( 25717600 )
2015
33
Intestinal tuberculosis previously mistreated as Crohn's disease and complicated with perforation: a case report and literature review. ( 26180746 )
2015
34
Critical complications of intestinal tuberculosis--a case report. ( 26305349 )
2015
35
Perforated Intestinal Tuberculosis in a Non-AIDS Immunocompromised Patient. ( 26451879 )
2015
36
Granulomas as the Most Useful Histopathological Feature in Distinguishing between Crohn's Disease and Intestinal Tuberculosis in Endoscopic Biopsy Specimens. ( 26656343 )
2015
37
Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection. ( 25691838 )
2015
38
Mycobacterium avium Subsp. avium infection in four veal calves: differentiation from intestinal tuberculosis. ( 24689051 )
2014
39
Differential diagnosis of intestinal tuberculosis from Crohn's disease and primary intestinal lymphoma in China. ( 25038210 )
2014
40
Immune thrombocytopenic purpura induced by intestinal tuberculosis in a liver transplant recipient. ( 25009408 )
2014
41
Fluorescent quantitative PCR of Mycobacterium tuberculosis for differentiating intestinal tuberculosis from Crohn's disease. ( 24519133 )
2014
42
Intestinal tuberculosis in a child living in a country with a low incidence of tuberculosis: a case report. ( 25346193 )
2014
43
Analysis of recent cases of intestinal tuberculosis in Japan. ( 24785886 )
2014
44
Routine diagnosis of intestinal tuberculosis and Crohn's disease in Southern India. ( 24803814 )
2014
45
Differential diagnosis of Crohn's disease and intestinal tuberculosis in patients with spontaneous small-bowel perforation. ( 24970687 )
2014
46
Systematic review with meta-analysis: accuracy of interferon-gamma releasing assay and anti-Saccharomyces cerevisiae antibody in differentiating intestinal tuberculosis from Crohn's disease in Asians. ( 24910240 )
2014
47
Visceral fat as a useful parameter in the differential diagnosis of Crohn's disease and intestinal tuberculosis. ( 25349562 )
2014
48
Comparative study of intestinal tuberculosis and primary small intestinal lymphoma. ( 24764686 )
2014
49
The diagnostic utility of mean platelet volume and red cell distribution width in active Crohn's disease and intestinal tuberculosis. ( 24749142 )
2014
50
Intestinal tuberculosis: a diagnostically-challenging case misdiagnosed as Crohn's disease at colorectal biopsy. ( 24897777 )
2014

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

GO Terms for Intestinal Tuberculosis

Molecular functions related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ATPase activity GO:0016887 9.16 ABCA3 ABCB8
2 transporter activity GO:0005215 8.96 ABCA3 ABCB8
3 ATPase activity, coupled to transmembrane movement of substances GO:0042626 8.62 ABCA3 ABCB8

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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