MCID: INT046
MIFTS: 37

Intestinal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Intestinal Tuberculosis

MalaCards integrated aliases for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 14
Tuberculosis of Intestines 69
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 34 014.8

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and intussusception, and has symptoms including abdominal pain, gastrointestinal bleeding and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto), and among its related pathways/superpathways is Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include intestine, liver and colon.

Related Diseases for Intestinal Tuberculosis

Diseases related to Intestinal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 gastrointestinal tuberculosis 32.5 ABCB8 CD53
2 intussusception 29.5 CD79A CRP
3 purpura 28.9 CD79A CRP
4 mycobacterium tuberculosis 1 10.8
5 crohn's disease 10.5
6 pulmonary tuberculosis 10.0
7 peritonitis 9.9
8 lymphoma 9.9
9 acute maxillary sinusitis 9.8 CD79A CRP
10 colitis 9.8
11 mucositis 9.8
12 tuberculous peritonitis 9.8
13 rapidly progressive glomerulonephritis 9.8 CD79A CRP
14 hypersensitivity vasculitis 9.8 CD79A CRP
15 hypersensitivity reaction type iii disease 9.8 CD79A CRP
16 pyelitis 9.8 CD79A CRP
17 endocardium disease 9.8 CD79A CRP
18 granulomatous hepatitis 9.8 CD79A CRP
19 dysentery 9.8 CD79A CRP
20 lymph node disease 9.8 CD79A CRP
21 exanthem 9.7 CD79A CRP
22 reactive arthritis 9.7 CD79A CRP
23 spondyloarthropathy 1 9.7 CD79A CRP
24 primary bacterial infectious disease 9.7 CD79A CRP
25 bone inflammation disease 9.7 CD79A CRP
26 chlamydia 9.7 CD79A CRP
27 blood group, i system 9.7
28 ulcerative colitis 9.7
29 inflammatory bowel disease 9.7
30 intestinal disease 9.7 CD79A CRP
31 end stage renal failure 9.7 CD79A CRP
32 respiratory system disease 9.7 CD79A CRP
33 urinary system disease 9.6 CD79A CRP
34 immune system disease 9.6 CD79A CRP
35 gastrointestinal system disease 9.6 CD79A CRP
36 vasculitis 9.6 CD79A CRP
37 colorectal cancer 9.6
38 rheumatoid arthritis 9.6
39 schistosoma mansoni infection, susceptibility/ 9.6
40 anemia, autoimmune hemolytic 9.6
41 celiac disease 1 9.6
42 hypoascorbemia 9.6
43 helicobacter pylori infection 9.6
44 gallbladder disease 1 9.6
45 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.6
46 polyarteritis nodosa, childhood-onset 9.6
47 chops syndrome 9.6
48 arthritis 9.6
49 chronic inflammatory demyelinating polyneuropathy 9.6
50 hemolytic anemia 9.6

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • abdominal pain
  • gastrointestinal bleeding
  • nausea
  • vomiting

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 4
2 Cola Nutraceutical Phase 4
3 Antitubercular Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914 Phase 4
2 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
3 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
4 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
5 MRI Differentiating Gut TB and Crohn's Recruiting NCT03096379

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

18
Intestine

MalaCards organs/tissues related to Intestinal Tuberculosis:

38
Liver, Colon, Testes, Small Intestine, Appendix, Kidney, Heart

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 293)
# Title Authors Year
1
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal BehAset's disease. ( 29446764 )
2018
2
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? Authors' reply. ( 29446137 )
2018
3
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? ( 29446132 )
2018
4
Differentiation between Crohn's Disease and Intestinal Tuberculosis in Children. ( 28489674 )
2017
5
Combination of Increased Visceral Fat and Long Segment Involvement: Development and Validation of an updated imaging marker for differentiating Crohn's Disease from Intestinal Tuberculosis. ( 29205485 )
2017
6
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
7
Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy. ( 28912984 )
2017
8
Is it intestinal tuberculosis again? Case report. ( 28726436 )
2017
9
Intestinal Tuberculosis Presenting as an Apple-Core Sign. ( 28270663 )
2017
10
Intestinal tuberculosis: a diagnostic challenge. ( 28609809 )
2017
11
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
12
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report. ( 28819499 )
2017
13
Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohn's Disease and Intestinal Tuberculosis. ( 28682807 )
2017
14
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
15
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
16
Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis. ( 28974897 )
2017
17
The diagnostic value of polymerase chain reaction for Mycobacterium tuberculosis to distinguish intestinal tuberculosis from crohn's disease: A meta-analysis. ( 28139494 )
2017
18
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2016
19
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016
20
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
21
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
22
Primary Enterolith in a Patient with Intestinal Tuberculosis: A Case Report. ( 27853338 )
2016
23
Differences in Clinical Manifestations according to the Positivity of Interferon-I^ Assay in Patients with Intestinal Tuberculosis. ( 27282272 )
2016
24
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016
25
Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans. ( 27296940 )
2016
26
Development and validation of visceral fat quantification as a surrogate marker for differentiation of Crohn's disease and Intestinal tuberculosis. ( 27532624 )
2016
27
Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. ( 27557645 )
2016
28
Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 27997555 )
2016
29
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
30
An Analysis of the Clinical, Endoscopic, and Pathologic Features of Intestinal Tuberculosis. ( 26974755 )
2016
31
Clinical and Laboratory Diagnosis of Intestinal Tuberculosis. ( 27231171 )
2016
32
Perforated Intestinal Tuberculosis in a Non-AIDS Immunocompromised Patient. ( 26451879 )
2015
33
Multiple, Pan-Enteric Perforation Secondary to Intestinal Tuberculosis. ( 26798540 )
2015
34
High faecal calprotectin levels in intestinal tuberculosis are associated with granulomas in intestinal biopsies. ( 25522183 )
2015
35
Critical complications of intestinal tuberculosis--a case report. ( 26305349 )
2015
36
P285. A novel scoring system for differential diagnosis between Crohn's disease and intestinal tuberculosis: A prospective study. ( 25717761 )
2015
37
Combined identifying granuloma and biopsy culture is useful for diagnosing intestinal tuberculosis. ( 25868516 )
2015
38
P139. Predictive Factors for Differentiating between Crohn's disease and Intestinal tuberculosis in Korea. ( 25717600 )
2015
39
Computerized tomography-based predictive model for differentiation of Crohn's disease from intestinal tuberculosis. ( 25966870 )
2015
40
Intestinal tuberculosis previously mistreated as Crohn's disease and complicated with perforation: a case report and literature review. ( 26180746 )
2015
41
Differences in clinical features of Crohn's disease and intestinal tuberculosis. ( 25834333 )
2015
42
Subcutaneous abscess at epidural catheter insertion site in a patient with intestinal tuberculosis. ( 26111664 )
2015
43
Computed tomographic enterography adds value to colonoscopy in differentiating Crohn's disease from intestinal tuberculosis: a potential diagnostic algorithm. ( 25675175 )
2015
44
Granulomas as the Most Useful Histopathological Feature in Distinguishing between Crohn's Disease and Intestinal Tuberculosis in Endoscopic Biopsy Specimens. ( 26656343 )
2015
45
Genome-wide gene expression analysis for target genes to differentiate patients with intestinal tuberculosis and Crohn's disease and discriminative value of FOXP3 mRNA expression. ( 25969456 )
2015
46
Extraintestinal manifestations of inflammatory bowel disease and intestinal tuberculosis: Frequency and relation with disease phenotype. ( 25663290 )
2015
47
Evaluation of intestinal tuberculosis by multi-slice computed tomography enterography. ( 26695641 )
2015
48
Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection. ( 25691838 )
2015
49
The features of intestinal tuberculosis by contrast-enhanced ultrasound. ( 26173398 )
2015
50
Differential diagnosis between Crohn's disease and intestinal tuberculosis using integrated parameters including clinical manifestations, T-SPOT, endoscopy and CT enterography. ( 26770348 )
2015

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

Pathways related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.61 CD79A NT5E

GO Terms for Intestinal Tuberculosis

Molecular functions related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transporter activity GO:0005215 8.96 ABCA3 ABCB8
2 ATPase activity, coupled to transmembrane movement of substances GO:0042626 8.62 ABCA3 ABCB8

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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