MCID: INT076
MIFTS: 24

Intracranial Sinus Thrombosis malady

Categories: Cardiovascular diseases, Neuronal diseases, Blood diseases

Aliases & Classifications for Intracranial Sinus Thrombosis

Aliases & Descriptions for Intracranial Sinus Thrombosis:

Name: Intracranial Sinus Thrombosis 12 14
Sinus Thrombosis, Intracranial 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3572
MeSH 42 D012851
UMLS 69 C0037198

Summaries for Intracranial Sinus Thrombosis

MalaCards based summary : Intracranial Sinus Thrombosis, also known as sinus thrombosis, intracranial, is related to orbital tenonitis and appendix lymphoma. An important gene associated with Intracranial Sinus Thrombosis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). The drugs Warfarin and Apixaban have been mentioned in the context of this disorder.

Related Diseases for Intracranial Sinus Thrombosis

Diseases related to Intracranial Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
id Related Disease Score Top Affiliating Genes
1 orbital tenonitis 10.2 PGBD1 RHNO1
2 appendix lymphoma 10.2 PGBD1 RHNO1
3 bestiality 10.2 PGBD1 RHNO1
4 seminoma 10.2 F3 RHNO1
5 influenza 10.2 F3 SERPINC1
6 freiberg's disease 10.2 F3 SERPINC1
7 hereditary endotheliopathy, retinopathy, nephropathy, and stroke 10.2 F3 SERPINC1
8 chorioretinal scar 10.2 F3 SERPINC1
9 mixed hepatoblastoma 10.2 F3 SERPINC1
10 bile duct signet ring cell carcinoma 10.2 PGBD1 RHNO1
11 hypertrichosis 10.2 F3 SERPINC1
12 dmd-related dilated cardiomyopathy 10.2 F3 SERPINC1
13 spinal cord lipoma 10.2 F3 SERPINC1
14 midline cystocele 10.2 F3 SERPINC1
15 neuronopathy, distal hereditary motor, type iid 10.1 F3 SERPINC1
16 secretory diarrhea myopathy and deafness 10.1 F3 SERPINC1
17 conjunctivochalasis 10.1 F3 SERPINC1
18 ductal carcinoma in situ 10.1 F3 SERPINC1
19 monocular exotropia 10.1 F3 SERPINC1
20 essential thrombocythemia 10.1 F3 SERPINC1
21 epstein-barr virus hepatitis 10.1 F3 SERPINC1
22 lobomycosis 10.1 F3 RHNO1
23 blepharoconjunctivitis 10.1 F3 SERPINC1
24 intestinal disaccharidase deficiency 10.1 F3 SERPINC1
25 lupus erythematosus 10.1 F3 SERPINC1
26 shwartzman phenomenon 10.1 NT5C3A RHNO1
27 septic myocarditis 10.1 F3 SERPINC1
28 hereditary alpha tryptasemia syndrome 10.1 F3 SERPINC1
29 zika virus congenital syndrome 10.1 F3 SERPINC1
30 scapuloperoneal myopathy, x-linked dominant 10.1 F3 SERPINC1
31 capillary hemangioma 10.1 F3 SERPINC1
32 pregnancy loss, recurrent 2 10.1 F3 SERPINC1
33 alcoholic gastritis 10.1 F3 SERPINC1
34 hennekam lymphangiectasia-lymphedema syndrome 2 10.1 F3 SERPINC1
35 hemolytic-uremic syndrome 10.1 F3 SERPINC1
36 uterine corpus cancer 10.1 F3 SERPINC1
37 pregnancy loss, recurrent 1 10.1 F3 SERPINC1
38 oguchi disease-2 10.1 F3 SERPINC1
39 thrombosis 10.1
40 thrombophilia due to activated protein c resistance 10.1 F3 SERPINC1
41 spinal multifocal clear cell meningioma 10.1 F3 SERPINC1
42 aids dementia complex 10.1 F3 SERPINC1
43 brill-zinsser disease 10.1 F3 SERPINC1
44 ocular hyperemia 10.1 F3 SERPINC1
45 granulomatous hepatitis 10.1 F3 SERPINC1
46 immunodeficiency, common variable, 6 10.1 F3 SERPINC1
47 sertoli-leydig cell tumor 10.1 F3 SERPINC1
48 leukocyte disease 10.1 F3 SERPINC1
49 haemonchiasis 10.1 F3 SERPINC1
50 myeloproliferative neoplasm 10.0 F3 SERPINC1

Graphical network of the top 20 diseases related to Intracranial Sinus Thrombosis:



Diseases related to Intracranial Sinus Thrombosis

Symptoms & Phenotypes for Intracranial Sinus Thrombosis

Drugs & Therapeutics for Intracranial Sinus Thrombosis

Drugs for Intracranial Sinus Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 44)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Warfarin Approved Phase 3 81-81-2 6691 54678486
2
Apixaban Approved Phase 3 503612-47-3 10182969
3
Asparaginase Approved Phase 3 9015-68-3
4
Pegaspargase Approved, Investigational Phase 3 130167-69-0
5
Dalteparin Approved Phase 2, Phase 3 9041-08-1
6
Heparin Approved, Investigational Phase 2, Phase 3 9005-49-6 772 46507594
7 Anticoagulants Phase 3,Phase 2
8 Antithrombin III Phase 3
9 Antithrombins Phase 3
10 Dabigatran Phase 3
11 HIV Protease Inhibitors Phase 3
12
protease inhibitors Phase 3
13 Serine Proteinase Inhibitors Phase 3
14 Factor Xa Inhibitors Phase 3
15 Pharmaceutical Solutions Phase 3
16 calcium heparin Phase 2, Phase 3
17 Calcium, Dietary Phase 2, Phase 3
18 Fibrinolytic Agents Phase 2, Phase 3
19 Heparin, Low-Molecular-Weight Phase 2, Phase 3
20 Plasminogen Phase 2, Phase 3
21 Tissue Plasminogen Activator Phase 2, Phase 3
22 serine Nutraceutical Phase 3
23
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757 53477783
24
Ethinyl Estradiol Approved 57-63-6 5991
25
Levonorgestrel Approved, Investigational 797-63-7, 17489-40-6 13109
26
Norelgestromin Approved 53016-31-2 13752005
27
Norgestrel Approved 6533-00-2 13109
28 Contraceptive Agents
29 Contraceptives, Oral
30 Contraceptives, Oral, Combined
31 Estradiol 17 beta-cypionate
32 Estradiol 3-benzoate
33 Estradiol valerate 979-32-8
34 Estrogens
35 Hormone Antagonists
36 Hormones
37 Hormones, Hormone Substitutes, and Hormone Antagonists
38 Ortho Evra
39 Polyestradiol phosphate
40 Ethinyl estradiol, levonorgestrel drug combination
41 Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
42 Norinyl
43 Thrombin
44
Cobalt 7440-48-4 104729

Interventional clinical trials:

(show all 11)
id Name Status NCT ID Phase
1 A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT) Recruiting NCT02913326 Phase 3
2 A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Pegylated (PEG) L-Asparaginase Recruiting NCT02369653 Phase 3
3 Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis Terminated NCT01204333 Phase 2, Phase 3
4 Relative Risks for Non-fatal Venous Thromboembolism, Ischemic Stroke and Myocardial Infarction in Users of ORTHO EVRA(Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared to Levonorgestrel-containing Oral Contraceptives. Completed NCT00511784
5 Study Of Lybrel In Relation To Venous Thromboembolism Completed NCT01297348
6 Impact of Cranioplasty On Cerebral Perfusion Completed NCT01113645
7 Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates Completed NCT00555932
8 Electrical Cardioversion of Recent Onset Atrial Fibrillation - Silent Thromboembolic Events, Reverse Atrial Remodeling Recruiting NCT02955004
9 Thrombosis Outcomes in Pediatric Venous Thromboembolism Recruiting NCT03068923
10 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Not yet recruiting NCT02711436
11 New Covered Stent (Willis) for the Endovascular Reconstruction of Intracranial Vessel Wall Defects Registry Not yet recruiting NCT02820779

Search NIH Clinical Center for Intracranial Sinus Thrombosis

Cochrane evidence based reviews: sinus thrombosis, intracranial

Genetic Tests for Intracranial Sinus Thrombosis

Anatomical Context for Intracranial Sinus Thrombosis

Publications for Intracranial Sinus Thrombosis

Articles related to Intracranial Sinus Thrombosis:

id Title Authors Year
1
A Case of Deep Vein Thrombosis and Intracranial Sinus Thrombosis: Possible rare complications of childhood abdominal tuberculosis. ( 28003904 )
2016
2
WITHDRAWN: Intracranial Sinus Thrombosis in Anorexia Nervosa. ( 20659740 )
2010
3
Successful management of an extensive intracranial sinus thrombosis in a patient undergoing IVF: case report and review of literature. ( 17349640 )
2007
4
Thunderclap headache: presentation of intracranial sinus thrombosis? ( 12887960 )
2003
5
Intracranial sinus thrombosis in a patient with Crohn disease and factor V Leiden mutation. ( 12873183 )
2003
6
Intracranial sinus thrombosis secondary to ear disease in an adolescent. ( 9176806 )
1997
7
Open thrombectomy combined with thrombolysis in massive intracranial sinus thrombosis. ( 7847137 )
1994
8
Cerebral infarction due to intracranial sinus thrombosis. ( 5835445 )
1965

Variations for Intracranial Sinus Thrombosis

Expression for Intracranial Sinus Thrombosis

Search GEO for disease gene expression data for Intracranial Sinus Thrombosis.

Pathways for Intracranial Sinus Thrombosis

GO Terms for Intracranial Sinus Thrombosis

Biological processes related to Intracranial Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hemostasis GO:0007599 8.62 F3 SERPINC1

Molecular functions related to Intracranial Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 F3 SERPINC1

Sources for Intracranial Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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