MCID: INT016
MIFTS: 37

Intraductal Papilloma malady

Summaries for Intraductal Papilloma

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64Wikipedia, 33MalaCards
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Wikipedia:64 Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in... more...

MalaCards: Intraductal Papilloma, also known as papilloma, intraductal, is related to papillary carcinoma and ductal carcinoma in situ. An important gene associated with Intraductal Papilloma is IDH1 (isocitrate dehydrogenase 1 (NADP+), soluble), and among its related pathways are Glutathione metabolism and Citric acid cycle (TCA cycle). The compounds Isocitric Acid and isocitrate have been mentioned in the context of this disorder. Affiliated tissues include lymph node, salivary gland and breast, and related mouse phenotypes are muscle and renal/urinary system.

Aliases & Classifications for Intraductal Papilloma

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH
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Aliases & Descriptions:

intraductal papilloma 8 10
papilloma, intraductal 61
papilloma intraductal 45
ductal papilloma 8


External Ids:

Disease Ontology8 DOID:1627
NCIt40 C3785
SNOMED-CT57 5244003
MeSH35 D018300

Related Diseases for Intraductal Papilloma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Intraductal Papilloma:



Diseases related to intraductal papilloma

Clinical Features for Intraductal Papilloma

Drugs & Therapeutics for Intraductal Papilloma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Intraductal Papilloma

Anatomical Context for Intraductal Papilloma

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33MalaCards
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MalaCards organs/tissues related to Intraductal Papilloma:

33
Lymph node, Salivary gland, Breast

Animal Models for Intraductal Papilloma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Intraductal Papilloma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.6TP63, CD44, MYH11, PRKG1
2MP:00053678.5MYH11, PRKG1, CD44, TP63
3MP:00053818.3TP63, PRKG1, MYH11, CD44

Publications for Intraductal Papilloma

Sources:
51PubMed
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Articles related to Intraductal Papilloma:

(show top 50)    (show all 95)
idTitleAuthorsYear
1
Management of benign intraductal solitary papilloma diagnosed on core needle biopsy. (23314624)
2013
2
Intraductal papilloma of the breast: A case report. (23396758)
2012
3
Surgical excision of intraductal breast papilloma diagnosed on core biopsy. (22510128)
2012
4
MRI features of intraductal papilloma of the breast: sheep in wolf's clothing? (21498361)
2011
5
Glucose transporter expression of intraductal papilloma of the breast detected by fluorodeoxyglucose positron emission tomography. (21519997)
2011
6
Is CD56 a specific and reliable neuroendocrine marker for discriminating between endocrine/neuroendocrine ductal carcinoma in situ and intraductal papilloma of the breast? (21166944)
2011
7
Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature. (20222992)
2010
8
"Signet-ring" cell invasive lobular carcinoma of the breast - accidental finding associated with intraductal papilloma: a case report. (19200374)
2009
9
Excision is indicated for intraductal papilloma of the breast diagnosed on core needle biopsy. (19402174)
2009
10
Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge. (19777298)
2009
11
Carcinoma in a solitary intraductal papilloma of the breast. (19261097)
2009
12
External herniation of a subareolar intraductal papilloma: a rare, yet beneficial, complication of conventional ductography. (19913136)
2009
13
Intraoral intraductal papilloma: a case report. (18201187)
2008
14
Intraductal carcinoma arising in intraductal papilloma in an axillary lymph node: review of the literature and proposed theories of evolution. (19061295)
2008
15
Intraductal papilloma of the parotid gland in a child. (17598121)
2007
16
Solitary intraductal papilloma of the breast--a diagnostic dilemma and the role of conferencing between surgeons and cytologist. (17183864)
2006
17
Intraductal papilloma: features on MR ductography using a microscopic coil. (16357375)
2006
18
Intraductal papilloma in a reconstructed breast: mammographic and sonographic appearance with pathologic correlation. (16448815)
2006
19
Myoepithelial cell staining patterns of papillary breast lesions: from intraductal papillomas to invasive papillary carcinomas. (15762278)
2005
20
Solitary intraductal papilloma of the male breast: diagnostic value of galactography. (12846873)
2003
21
Magnetic resonance imaging of intraductal papilloma of the breast. (14599539)
2003
22
Study of CD44v6 protein expression in intraductal papilloma and its malignant transformation of breast]. (12452061)
2002
23
Intraductal papilloma of the parotid gland in a child. (12121243)
2002
24
Case of the Month. Giant multiple intraductal papilloma of the breast: a case report and review of the literature. (11320612)
2001
25
Benign intraductal papilloma: diagnosis and removal at stereotactic vacuum-assisted directional biopsy guided by galactography. (11161181)
2001
26
Case report: galactography-guided wire localization of an intraductal papilloma. (11162702)
2001
27
Sebaceous gland metaplasia in intraductal papilloma of the breast. (11407480)
2001
28
Diagnosis of ductal carcinoma in situ (DCIS) and intraductal papilloma using fluorescence in situ hybridization (FISH) analysis. (11114860)
2000
29
Incidental treatment of nipple discharge caused by benign intraductal papilloma through diagnostic Mammotome biopsy. (10789774)
2000
30
Solitary intraductal papilloma: findings at MR imaging and MR galactography. (9888758)
1999
31
Intraductal papilloma of the salivary gland. A report of two cases with diagnosis by fine needle aspiration biopsy. (10578993)
1999
32
Diagnosis please. Case 8: solitary intraductal papilloma. (10207483)
1999
33
Intraductal papilloma of the breast. (10511152)
1999
34
Breast imaging case of the day. Benign intraductal papilloma with focal atypical papillomatous hyperplasia. (9599399)
1998
35
A case of intraductal papilloma of breast in advanced age. (10209933)
1998
36
Intraductal papilloma of the minor salivary gland involving the nasal cavity: is it a distinct histopathologic entity? (9627248)
1998
37
Different incidence of loss of heterozygosity on chromosome 16q between intraductal papilloma and intracystic papillary carcinoma of the breast. (7961109)
1994
38
Intraductal papilloma of the male breast: an ultrastructural and immunohistochemical study. (7855934)
1994
39
Clonal analysis of solitary intraductal papilloma of the breast by means of polymerase chain reaction. (7911274)
1994
40
Intraductal breast papilloma with squamous metaplasia in Peutz-Jeghers syndrome. (6500554)
1984
41
The value of ductogalactography in the diagnosis of intraductal papilloma. (6665877)
1983
42
Solitary intraductal papilloma of the male breast. (7244769)
1981
43
Intraductal papilloma arising in supernumerary vulvar breast tissue. (7360456)
1980
44
Solitary intraductal papilloma of the minor salivary glands. (1057130)
1975
45
Giant form of intraductal papilloma of the breast. (5552896)
1971
46
Intraductal papilloma of the breast. (13772356)
1961
47
Intraductal papilloma of the breast. (13455399)
1957
48
Management of intraductal papilloma; its relationship to cancer of the breast. (13340064)
1956
49
Intraductal papilloma of the breast. (13254504)
1955
50
Surgical management of benign intraductal papilloma of the breast. (14911043)
1952

Genetic Variations for Intraductal Papilloma

Expression for genes affiliated with Intraductal Papilloma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Intraductal Papilloma

Search GEO for disease gene expression data for Intraductal Papilloma.

Pathways for genes affiliated with Intraductal Papilloma

Sources:
30KEGG, 38NCBI BioSystems Database, 54Reactome
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Pathways related to Intraductal Papilloma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Glutathione metabolism
Hide members
9.8IDH2, IDH1
2
Hide members
9.8IDH2, IDH1
39.8IDH2, IDH1

Compounds for genes affiliated with Intraductal Papilloma

Sources:
11DrugBank, 24HMDB, 45Novoseek
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Compounds related to Intraductal Papilloma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1Isocitric Acid11 2410.9IDH2, IDH1
2isocitrate459.8IDH1, IDH2
3hematoxylin459.6TP63, MYH11
4hpaii459.5CD44, PRKG1
5paraffin458.8MYH11, CD44, TP63
6vegf458.6TP63, CD44, MYH11, PRKG1
7estrogen458.5TP63, CD44, MYH11, PRKG1

GO Terms for genes affiliated with Intraductal Papilloma

Sources:
16Gene Ontology
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Cellular components related to Intraductal Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:0058297.9TP63, MYH11, PRKG1, DOCK4, IDH1

Biological processes related to Intraductal Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glyoxylate cycleGO:0060979.8IDH2, IDH1
2tricarboxylic acid cycleGO:0060999.8IDH2, IDH1
3isocitrate metabolic processGO:0061029.7IDH2, IDH1
42-oxoglutarate metabolic processGO:0061039.5IDH2, IDH1

Molecular functions related to Intraductal Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1NAD bindingGO:0512879.8IDH2, IDH1
2isocitrate dehydrogenase (NADP+) activityGO:0044509.5IDH2, IDH1

Products for genes affiliated with Intraductal Papilloma

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Sources for Intraductal Papilloma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet