MCID: INT016
MIFTS: 33

Intraductal Papilloma malady

Category: Cancer diseases

Aliases & Classifications for Intraductal Papilloma

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Aliases & Descriptions for Intraductal Papilloma:

Name: Intraductal Papilloma 11 13
Papilloma, Intraductal 39 68
 
Papilloma Intraductal 50
Ductal Papilloma 11

Classifications:



External Ids:

Disease Ontology11 DOID:1627
MeSH39 D018300
SNOMED-CT62 5244003
NCIt45 C3785

Summaries for Intraductal Papilloma

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Wikipedia:71 Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in... more...

MalaCards based summary: Intraductal Papilloma, also known as papilloma, intraductal, is related to breast disease and breast duct papilloma. An important gene associated with Intraductal Papilloma is TP63 (Tumor Protein P63), and among its related pathways are Citrate cycle (TCA cycle) and Peroxisome. Affiliated tissues include breast, salivary gland and lymph node, and related mouse phenotypes are neoplasm and digestive/alimentary.

Related Diseases for Intraductal Papilloma

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Diseases related to Intraductal Papilloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
idRelated DiseaseScoreTop Affiliating Genes
1breast disease11.1
2breast duct papilloma11.0
3papilloma10.8
4optic disk drusen10.1IDH1, IDH2
5enterovesical fistula10.1IDH1, IDH2
6acrocallosal syndrome10.1IDH1, IDH2
7neurilemmoma10.1IDH1, IDH2
8testis refractory cancer10.1IDH1, IDH2
9cystinosis, nephropathic10.1IDH1, IDH2
10small cell osteogenic sarcoma10.1IDH1, IDH2
11glycogen storage disease type 010.1IDH1, IDH2
12angioma hereditary neurocutaneous10.1IDH1, IDH2
13neuropathy, ataxia, and retinitis pigmentosa10.1IDH1, IDH2
14spinal cord astrocytoma10.1IDH1, IDH2
15prosopagnosia10.1IDH1, IDH2
16cystic lymphangioma10.1IDH1, IDH2
17cutaneous adenocystic carcinoma10.1CD44, IDH1
18ductal carcinoma in situ10.1
19papillary carcinoma10.1
20agammaglobulinemia 8, autosomal dominant10.1IDH1, IDH2
21gummatous syphilis10.1IDH1, IDH2
22amyloid tumor10.1IDH1, IDH2
23t-cell adult acute lymphocytic leukemia10.1IDH1, IDH2
24allergic hypersensitivity disease10.1IDH1, IDH2
25vascular cancer10.1IDH1, IDH2
26asynchronous multifocal osteogenic sarcoma10.0IDH1, IDH2
27popliteal pterygium syndrome, bartsocas-papas type10.0MYH11, TP63
28macrosomia with microphthalmia, lethal10.0IDH1, IDH2
29basophilic carcinoma10.0IDH1, IDH2
30systemic lupus erythematosus 210.0IDH1, IDH2
31gastroesophageal junction adenocarcinoma10.0IDH1, IDH2
32breast cancer9.9
33tmem231-related meckel syndrome9.8MYH11, PRKG1
34hyperprolactinemia9.7
35adenocarcinoma9.7
36papillary adenocarcinoma9.7
37cranioectodermal dysplasia 19.6IDH1, IDH2, MYH11
38breast papillomatosis9.1CD44, DOCK4, IDH1, IDH2, MYH11, PRKG1

Graphical network of the top 20 diseases related to Intraductal Papilloma:



Diseases related to intraductal papilloma

Symptoms & Phenotypes for Intraductal Papilloma

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MGI Mouse Phenotypes related to Intraductal Papilloma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.5CD44, DOCK4, IDH2, TP63
2MP:00053819.0CD44, MYH11, PRKG1, TP63
3MP:00053699.0CD44, MYH11, PRKG1, TP63
4MP:00053679.0CD44, MYH11, PRKG1, TP63
5MP:00053888.5CD44, IDH1, MYH11, TP63
6MP:00053858.1CD44, DOCK4, IDH2, MYH11, PRKG1, TP63

Drugs & Therapeutics for Intraductal Papilloma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients With Pathologic Nipple DischargeRecruitingNCT01901562Phase 1, Phase 2
2The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle BiopsyRecruitingNCT02489617

Search NIH Clinical Center for Intraductal Papilloma


Cochrane evidence based reviews: papilloma, intraductal

Genetic Tests for Intraductal Papilloma

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Anatomical Context for Intraductal Papilloma

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MalaCards organs/tissues related to Intraductal Papilloma:

36
Breast, Salivary gland, Lymph node

Publications for Intraductal Papilloma

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Articles related to Intraductal Papilloma:

(show top 50)    (show all 102)
idTitleAuthorsYear
1
Floor of Mouth Mass. Intraductal papilloma. (26583524)
2016
2
Intraductal papilloma of the male breast. (26860828)
2016
3
Intraductal Papilloma with Benign Pathology on Breast Core Biopsy: To Excise or Not? (26960929)
2016
4
Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe? (27499780)
2016
5
A Case of Intraductal Papilloma of the Breast With High 18F-FDG Uptake on PET/CT. (26164173)
2015
6
Immunocytochemical analysis of p63 and 34I^E12 in fine needle aspiration cytology specimens for breast lesions: a potentially useful discriminatory marker between intraductal papilloma and ductal carcinoma inA situ. (25810244)
2015
7
Exuberant squamous metaplasia in an intraductal papilloma of breast. (25583984)
2015
8
The significance of combined CK5/6 and p63 immunohistochemistry in predicting the risks of subsequent carcinoma development in intraductal papilloma of the breast. (25572436)
2015
9
Collagen Type XI Alpha 1 Expression in Intraductal Papillomas Predicts Malignant Recurrence. (26448946)
2015
10
A prolapsed intraductal papilloma: a case report. (28058341)
2015
11
Diagnosis of a Nonpalpable Intraductal Papilloma without Radiological Abnormality by Nipple Discharge Smear Examination: A Case Report. (24737934)
2014
12
MRI characteristics of intraductal papilloma. (24696194)
2014
13
Intraductal papilloma in an axillary lymph node of a patient with human immunodeficiency virus: a case report and review of the literature. (24884898)
2014
14
Concurrent fibroadenoma and intraductal papilloma - A recurring complex lesion in a premenarcheal girl. (23218483)
2013
15
Intraductal papilloma: atypical presentation. (23762648)
2013
16
Mammotome biopsy in diagnosing and treatment of intraductal papilloma of the breast. (23640929)
2013
17
Intraductal papilloma of the breast: A case report. (23396758)
2012
18
Combined evaluation of CK5/6, ER, p63, and MUC3 for distinguishing breast intraductal papilloma from ductal carcinoma in situ. (22612506)
2012
19
Glucose transporter expression of intraductal papilloma of the breast detected by fluorodeoxyglucose positron emission tomography. (21519997)
2011
20
Intraductal papilloma of the breast in association with preoncogenic gene of breast cancer. (23569749)
2011
21
MRI features of intraductal papilloma of the breast: sheep in wolf's clothing? (21498361)
2011
22
Enlarging unilateral breast mass in an adolescent male: an unusual presentation of intraductal papilloma. (21616226)
2011
23
Is CD56 a specific and reliable neuroendocrine marker for discriminating between endocrine/neuroendocrine ductal carcinoma in situ and intraductal papilloma of the breast? (21166944)
2011
24
Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature. (20222992)
2010
25
Evaluation of CD56 and CD57 immunostainings for discrimination between endocrine ductal carcinoma in situ and intraductal papilloma. (20518901)
2010
26
Intraductal papilloma arising from sublingual minor salivary gland: case report and immunohistochemical study. (19426904)
2009
27
External herniation of a subareolar intraductal papilloma: a rare, yet beneficial, complication of conventional ductography. (19913136)
2009
28
Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge. (19777298)
2009
29
Excision is indicated for intraductal papilloma of the breast diagnosed on core needle biopsy. (19402174)
2009
30
Signet-ring" cell invasive lobular carcinoma of the breast - accidental finding associated with intraductal papilloma: a case report. (19200374)
2009
31
Carcinoma in a solitary intraductal papilloma of the breast. (19261097)
2009
32
A potential diagnostic pitfall in aspiration cytology in intraductal papilloma of the parotid gland. (19697742)
2009
33
Benign epithelial proliferations in axillary lymph nodes with ipsilateral breast in situ ductal carcinoma and intraductal papilloma of the breast. (18439159)
2008
34
Complicated solitary intraductal papilloma of the breast. (17971167)
2008
35
Intraoral intraductal papilloma: a case report. (18201187)
2008
36
Intraductal carcinoma arising in intraductal papilloma in an axillary lymph node: review of the literature and proposed theories of evolution. (19061295)
2008
37
Myoepithelial cells in solid variant of intraductal papillary carcinoma of the breast: a potential diagnostic pitfall and a proposal of an immunohistochemical panel in the differential diagnosis with intraductal papilloma with usual ductal hyperplasia. (17377808)
2007
38
Intraductal papilloma of the parotid gland in a child. (17598121)
2007
39
Solitary intraductal papilloma of the breast--a diagnostic dilemma and the role of conferencing between surgeons and cytologist. (17183864)
2006
40
Intraductal papilloma: features on MR ductography using a microscopic coil. (16357375)
2006
41
Intraductal papilloma in a reconstructed breast: mammographic and sonographic appearance with pathologic correlation. (16448815)
2006
42
Infarcted intraductal papilloma of the breast: cytologic features with stage of infarction. (16604546)
2006
43
Intraductal papilloma arising from Stensen's duct. (16343407)
2005
44
Myoepithelial cell staining patterns of papillary breast lesions: from intraductal papillomas to invasive papillary carcinomas. (15762278)
2005
45
Intraductal papilloma of the breast: F-18 FDG PET demonstration. (15965323)
2005
46
Cytokeratins in papillary lesions of the breast: is there a role in distinguishing intraductal papilloma from papillary ductal carcinoma in situ? (15832086)
2005
47
Intraductal papilloma with "comedo-like" necrosis, a diagnostic pitfall. (15494933)
2004
48
Solitary intraductal papilloma of the male breast: diagnostic value of galactography. (12846873)
2003
49
Magnetic resonance imaging of intraductal papilloma of the breast. (14599539)
2003
50
Study of CD44v6 protein expression in intraductal papilloma and its malignant transformation of breast]. (12452061)
2002

Variations for Intraductal Papilloma

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Expression for genes affiliated with Intraductal Papilloma

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Search GEO for disease gene expression data for Intraductal Papilloma.

Pathways for genes affiliated with Intraductal Papilloma

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GO Terms for genes affiliated with Intraductal Papilloma

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Cellular components related to Intraductal Papilloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi apparatusGO:00057948.3CD44, DOCK4, PRKG1, TP63
2cytosolGO:00058297.5CD44, DOCK4, IDH1, IDH2, MYH11, PRKG1

Biological processes related to Intraductal Papilloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
12-oxoglutarate metabolic processGO:00061039.9IDH1, IDH2
2glyoxylate cycleGO:00060979.9IDH1, IDH2
3isocitrate metabolic processGO:00061029.9IDH1, IDH2
4tricarboxylic acid cycleGO:00060999.5IDH1, IDH2

Molecular functions related to Intraductal Papilloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1isocitrate dehydrogenase (NADP+) activityGO:000445010.0IDH1, IDH2
2isocitrate dehydrogenase activityGO:000444810.0IDH1, IDH2
3NAD bindingGO:00512879.9IDH1, IDH2
4oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00166169.5IDH1, IDH2

Sources for Intraductal Papilloma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet