MCID: INT016
MIFTS: 33

Intraductal Papilloma malady

Categories: Cancer diseases

Aliases & Classifications for Intraductal Papilloma

Aliases & Descriptions for Intraductal Papilloma:

Name: Intraductal Papilloma 12 14
Papilloma, Intraductal 42 69
Papilloma Intraductal 52
Ductal Papilloma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1627
MeSH 42 D018300
NCIt 47 C3785
SNOMED-CT 64 5244003
UMLS 69 C0206713

Summaries for Intraductal Papilloma

MalaCards based summary : Intraductal Papilloma, also known as papilloma, intraductal, is related to breast disease and breast duct papilloma. An important gene associated with Intraductal Papilloma is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Citrate cycle (TCA cycle) and Peroxisome. Affiliated tissues include breast, salivary gland and lymph node, and related phenotypes are cardiovascular system and digestive/alimentary

Wikipedia : 71 Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in... more...

Related Diseases for Intraductal Papilloma

Diseases related to Intraductal Papilloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
id Related Disease Score Top Affiliating Genes
1 breast disease 11.1
2 breast duct papilloma 11.0
3 papilloma 10.8
4 optic disk drusen 10.1 IDH1 IDH2
5 enterovesical fistula 10.1 IDH1 IDH2
6 acrocallosal syndrome 10.1 IDH1 IDH2
7 neurilemmoma 10.1 IDH1 IDH2
8 testis refractory cancer 10.1 IDH1 IDH2
9 cystinosis, nephropathic 10.1 IDH1 IDH2
10 small cell osteogenic sarcoma 10.1 IDH1 IDH2
11 glycogen storage disease type 0 10.1 IDH1 IDH2
12 angioma hereditary neurocutaneous 10.1 IDH1 IDH2
13 neuropathy, ataxia, and retinitis pigmentosa 10.1 IDH1 IDH2
14 spinal cord astrocytoma 10.1 IDH1 IDH2
15 prosopagnosia 10.1 IDH1 IDH2
16 cystic lymphangioma 10.1 IDH1 IDH2
17 cutaneous adenocystic carcinoma 10.1 CD44 IDH1
18 ductal carcinoma in situ 10.1
19 papillary carcinoma 10.1
20 agammaglobulinemia 8, autosomal dominant 10.1 IDH1 IDH2
21 gummatous syphilis 10.1 IDH1 IDH2
22 amyloid tumor 10.1 IDH1 IDH2
23 t-cell adult acute lymphocytic leukemia 10.1 IDH1 IDH2
24 allergic hypersensitivity disease 10.1 IDH1 IDH2
25 vascular cancer 10.1 IDH1 IDH2
26 asynchronous multifocal osteogenic sarcoma 10.0 IDH1 IDH2
27 popliteal pterygium syndrome, bartsocas-papas type 10.0 MYH11 TP63
28 macrosomia with microphthalmia, lethal 10.0 IDH1 IDH2
29 basophilic carcinoma 10.0 IDH1 IDH2
30 systemic lupus erythematosus 2 10.0 IDH1 IDH2
31 gastroesophageal junction adenocarcinoma 10.0 IDH1 IDH2
32 breast cancer 9.9
33 tmem231-related meckel syndrome 9.8 MYH11 PRKG1
34 adenocarcinoma 9.7
35 papillary adenocarcinoma 9.7
36 hyperprolactinemia 9.7
37 cranioectodermal dysplasia 1 9.6 IDH1 IDH2 MYH11
38 breast papillomatosis 9.1 CD44 DOCK4 IDH1 IDH2 MYH11 PRKG1

Graphical network of the top 20 diseases related to Intraductal Papilloma:



Diseases related to Intraductal Papilloma

Symptoms & Phenotypes for Intraductal Papilloma

MGI Mouse Phenotypes related to Intraductal Papilloma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.85 PRKG1 TP63 CD44 DOCK4 IDH2 MYH11
2 digestive/alimentary MP:0005381 9.62 CD44 MYH11 PRKG1 TP63
3 muscle MP:0005369 9.56 CD44 MYH11 PRKG1 TP63
4 neoplasm MP:0002006 9.46 CD44 DOCK4 IDH2 TP63
5 renal/urinary system MP:0005367 9.26 CD44 MYH11 PRKG1 TP63
6 respiratory system MP:0005388 8.92 CD44 IDH1 MYH11 TP63

Drugs & Therapeutics for Intraductal Papilloma

Interventional clinical trials:


id Name Status NCT ID Phase
1 Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients With Pathologic Nipple Discharge Recruiting NCT01901562 Phase 1, Phase 2
2 The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy Recruiting NCT02489617

Search NIH Clinical Center for Intraductal Papilloma

Cochrane evidence based reviews: papilloma, intraductal

Genetic Tests for Intraductal Papilloma

Anatomical Context for Intraductal Papilloma

MalaCards organs/tissues related to Intraductal Papilloma:

39
Breast, Salivary Gland, Lymph Node

Publications for Intraductal Papilloma

Articles related to Intraductal Papilloma:

(show top 50) (show all 102)
id Title Authors Year
1
Floor of Mouth Mass. Intraductal papilloma. ( 26583524 )
2016
2
Intraductal papilloma of the male breast. ( 26860828 )
2016
3
Intraductal Papilloma with Benign Pathology on Breast Core Biopsy: To Excise or Not? ( 26960929 )
2016
4
Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe? ( 27499780 )
2016
5
A Case of Intraductal Papilloma of the Breast With High 18F-FDG Uptake on PET/CT. ( 26164173 )
2015
6
Immunocytochemical analysis of p63 and 34I^E12 in fine needle aspiration cytology specimens for breast lesions: a potentially useful discriminatory marker between intraductal papilloma and ductal carcinoma inA situ. ( 25810244 )
2015
7
Exuberant squamous metaplasia in an intraductal papilloma of breast. ( 25583984 )
2015
8
The significance of combined CK5/6 and p63 immunohistochemistry in predicting the risks of subsequent carcinoma development in intraductal papilloma of the breast. ( 25572436 )
2015
9
Collagen Type XI Alpha 1 Expression in Intraductal Papillomas Predicts Malignant Recurrence. ( 26448946 )
2015
10
A prolapsed intraductal papilloma: a case report. ( 28058341 )
2015
11
Diagnosis of a Nonpalpable Intraductal Papilloma without Radiological Abnormality by Nipple Discharge Smear Examination: A Case Report. ( 24737934 )
2014
12
MRI characteristics of intraductal papilloma. ( 24696194 )
2014
13
Intraductal papilloma in an axillary lymph node of a patient with human immunodeficiency virus: a case report and review of the literature. ( 24884898 )
2014
14
Concurrent fibroadenoma and intraductal papilloma - A recurring complex lesion in a premenarcheal girl. ( 23218483 )
2013
15
Intraductal papilloma: atypical presentation. ( 23762648 )
2013
16
Mammotome biopsy in diagnosing and treatment of intraductal papilloma of the breast. ( 23640929 )
2013
17
Intraductal papilloma of the breast: A case report. ( 23396758 )
2012
18
Combined evaluation of CK5/6, ER, p63, and MUC3 for distinguishing breast intraductal papilloma from ductal carcinoma in situ. ( 22612506 )
2012
19
Glucose transporter expression of intraductal papilloma of the breast detected by fluorodeoxyglucose positron emission tomography. ( 21519997 )
2011
20
Intraductal papilloma of the breast in association with preoncogenic gene of breast cancer. ( 23569749 )
2011
21
MRI features of intraductal papilloma of the breast: sheep in wolf's clothing? ( 21498361 )
2011
22
Enlarging unilateral breast mass in an adolescent male: an unusual presentation of intraductal papilloma. ( 21616226 )
2011
23
Is CD56 a specific and reliable neuroendocrine marker for discriminating between endocrine/neuroendocrine ductal carcinoma in situ and intraductal papilloma of the breast? ( 21166944 )
2011
24
Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature. ( 20222992 )
2010
25
Evaluation of CD56 and CD57 immunostainings for discrimination between endocrine ductal carcinoma in situ and intraductal papilloma. ( 20518901 )
2010
26
Intraductal papilloma arising from sublingual minor salivary gland: case report and immunohistochemical study. ( 19426904 )
2009
27
External herniation of a subareolar intraductal papilloma: a rare, yet beneficial, complication of conventional ductography. ( 19913136 )
2009
28
Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge. ( 19777298 )
2009
29
Excision is indicated for intraductal papilloma of the breast diagnosed on core needle biopsy. ( 19402174 )
2009
30
"Signet-ring" cell invasive lobular carcinoma of the breast - accidental finding associated with intraductal papilloma: a case report. ( 19200374 )
2009
31
Carcinoma in a solitary intraductal papilloma of the breast. ( 19261097 )
2009
32
A potential diagnostic pitfall in aspiration cytology in intraductal papilloma of the parotid gland. ( 19697742 )
2009
33
Benign epithelial proliferations in axillary lymph nodes with ipsilateral breast in situ ductal carcinoma and intraductal papilloma of the breast. ( 18439159 )
2008
34
Complicated solitary intraductal papilloma of the breast. ( 17971167 )
2008
35
Intraoral intraductal papilloma: a case report. ( 18201187 )
2008
36
Intraductal carcinoma arising in intraductal papilloma in an axillary lymph node: review of the literature and proposed theories of evolution. ( 19061295 )
2008
37
Myoepithelial cells in solid variant of intraductal papillary carcinoma of the breast: a potential diagnostic pitfall and a proposal of an immunohistochemical panel in the differential diagnosis with intraductal papilloma with usual ductal hyperplasia. ( 17377808 )
2007
38
Intraductal papilloma of the parotid gland in a child. ( 17598121 )
2007
39
Solitary intraductal papilloma of the breast--a diagnostic dilemma and the role of conferencing between surgeons and cytologist. ( 17183864 )
2006
40
Intraductal papilloma: features on MR ductography using a microscopic coil. ( 16357375 )
2006
41
Intraductal papilloma in a reconstructed breast: mammographic and sonographic appearance with pathologic correlation. ( 16448815 )
2006
42
Infarcted intraductal papilloma of the breast: cytologic features with stage of infarction. ( 16604546 )
2006
43
Intraductal papilloma arising from Stensen's duct. ( 16343407 )
2005
44
Myoepithelial cell staining patterns of papillary breast lesions: from intraductal papillomas to invasive papillary carcinomas. ( 15762278 )
2005
45
Intraductal papilloma of the breast: F-18 FDG PET demonstration. ( 15965323 )
2005
46
Cytokeratins in papillary lesions of the breast: is there a role in distinguishing intraductal papilloma from papillary ductal carcinoma in situ? ( 15832086 )
2005
47
Intraductal papilloma with "comedo-like" necrosis, a diagnostic pitfall. ( 15494933 )
2004
48
Solitary intraductal papilloma of the male breast: diagnostic value of galactography. ( 12846873 )
2003
49
Magnetic resonance imaging of intraductal papilloma of the breast. ( 14599539 )
2003
50
[Study of CD44v6 protein expression in intraductal papilloma and its malignant transformation of breast]. ( 12452061 )
2002

Variations for Intraductal Papilloma

Expression for Intraductal Papilloma

Search GEO for disease gene expression data for Intraductal Papilloma.

Pathways for Intraductal Papilloma

Pathways related to Intraductal Papilloma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.17 IDH1 IDH2
2 10.87 IDH1 IDH2
3
Show member pathways
9.74 IDH1 IDH2

GO Terms for Intraductal Papilloma

Cellular components related to Intraductal Papilloma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 Golgi apparatus GO:0005794 9.26 CD44 DOCK4 PRKG1 TP63
2 cytosol GO:0005829 9.17 CD44 DOCK4 IDH1 IDH2 MYH11 PRKG1

Biological processes related to Intraductal Papilloma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.26 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.16 IDH1 IDH2
3 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
4 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Intraductal Papilloma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 NAD binding GO:0051287 9.26 IDH1 IDH2
2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
3 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH1 IDH2
4 isocitrate dehydrogenase activity GO:0004448 8.62 IDH1 IDH2

Sources for Intraductal Papilloma

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