MCID: INT079
MIFTS: 40

Intrahepatic Cholangiocarcinoma malady

Rare diseases, Cancer diseases, Liver diseases categories
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Summaries for Intrahepatic Cholangiocarcinoma

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NIH Rare Diseases:42 Intrahepatic cholangiocarcinoma is a cancer that develops in the cells within the bile ducts; both inside and outside the liver. the terms cholangiocarinoma and bile duct cancer are often used to refer to the same condition. this condition occurs slightly more often in males than females and usually affects people who are between 50-70 years old. signs and symptoms of intrahepatic cholangiocarcinoma include jaundice, abdominal pain, fever, weight loss, weakness and itching. treatment options may include surgery to remove the bile duct and parts of the liver, chemotherapy and radiation. last updated: 4/1/2014

MalaCards based summary: Intrahepatic Cholangiocarcinoma, also known as intrahepatic bile duct carcinoma, is related to cholangiocarcinoma and hepatitis. An important gene associated with Intrahepatic Cholangiocarcinoma is MUC1 (mucin 1, cell surface associated). Affiliated tissues include liver, lymph node and colon.

Aliases & Classifications for Intrahepatic Cholangiocarcinoma

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Intrahepatic Cholangiocarcinoma, Aliases & Descriptions:

Name: Intrahepatic Cholangiocarcinoma 8 42 62
Intrahepatic Bile Duct Carcinoma 8 62
 
Bile Duct Cancer 42 62
Peripheral Cholangiocarcinoma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Liver diseases


External Ids:

Disease Ontology8 DOID:4928
MeSH34 C535533
SNOMED-CT57 109842005
NCIt39 C35417

Related Diseases for Intrahepatic Cholangiocarcinoma

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Graphical network of the top 20 diseases related to Intrahepatic Cholangiocarcinoma:



Diseases related to intrahepatic cholangiocarcinoma

Symptoms for Intrahepatic Cholangiocarcinoma

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Drugs & Therapeutics for Intrahepatic Cholangiocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Intrahepatic Cholangiocarcinoma

Search NIH Clinical Center for Intrahepatic Cholangiocarcinoma

Genetic Tests for Intrahepatic Cholangiocarcinoma

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Anatomical Context for Intrahepatic Cholangiocarcinoma

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MalaCards organs/tissues related to Intrahepatic Cholangiocarcinoma:

32
Liver, Lymph node, Colon, Brain, Skeletal muscle, Endothelial, Neutrophil, T cells, Small intestine, Kidney, Lung, Thyroid, Ovary, Testis, Testes, Fetal liver

Animal Models for Intrahepatic Cholangiocarcinoma or affiliated genes

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Publications for Intrahepatic Cholangiocarcinoma

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Articles related to Intrahepatic Cholangiocarcinoma:

(show top 50)    (show all 558)
idTitleAuthorsYear
1
Diagnosis and management of intrahepatic cholangiocarcinoma: A comprehensive update for the radiologist. (25240565)
2014
2
CXCL5 contributes to tumor metastasis and recurrence of intrahepatic cholangiocarcinoma by recruiting infiltrative intratumoral neutrophils. (24293410)
2014
3
Liver transplantation for intrahepatic cholangiocarcinoma--Authors' reply. (25263671)
2014
4
Prediction of the Postoperative Prognosis of Intrahepatic Cholangiocarcinoma (ICC): Importance of Preoperatively-Determined Anatomic Invasion Level and Number of Tumors. (24122559)
2013
5
Clinical significances of cancer stem cells markers in patients with intrahepatic cholangiocarcinoma who underwent hepatectomy. (23645762)
2013
6
Hepatobiliary resection with concomitant resection of the inferior vena cava for advanced intrahepatic cholangiocarcinoma: report of a case. (22961194)
2013
7
Intrahepatic cholangiocarcinoma: impact of genetic hemochromatosis on outcome and overall survival after surgical resection. (23183056)
2013
8
The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma. (23688168)
2013
9
Notching up on the cellular origins of intrahepatic cholangiocarcinoma. (23390051)
2013
10
Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma. (23953227)
2013
11
Different roles of inducible nitric oxide synthase and cyclooxygenase-2 in carcinogenesis and metastasis of intrahepatic cholangiocarcinoma. (23260331)
2013
12
Yttrium-90 radioembolization for unresectable standard-chemorefractory intrahepatic cholangiocarcinoma: survival, efficacy, and safety study. (22956045)
2013
13
A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. (22729936)
2012
14
Clinicopathological significance of E-cadherin, I^-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma. (22281980)
2012
15
Treatment of recurrent intrahepatic cholangiocarcinoma. (23132419)
2012
16
Periductal infiltrating type of intrahepatic cholangiocarcinoma: a rare macroscopic type without any apparent mass. (22350300)
2012
17
The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas. (21874010)
2012
18
Pathobiological implications of MUC16/CA125 expression in intrahepatic cholangiocarcinoma-mass forming type. (22286058)
2012
19
Immunization with aspartate-I^-hydroxylase-loaded dendritic cells produces antitumor effects in a rat model of intrahepatic cholangiocarcinoma. (21898484)
2012
20
Claudin-18 in biliary neoplasms. Its significance in the classification of intrahepatic cholangiocarcinoma. (21607649)
2011
21
A case of intrahepatic cholangiocarcinoma with marked mucus production. (22128317)
2011
22
Mixed hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma in patients undergoing transplantation for hepatocellular carcinoma. (21438129)
2011
23
Ubiquitin-specific protease 14 expression associated with intrahepatic cholangiocarcinoma cell differentiation. (21627382)
2011
24
Different roles of S100P overexpression in intrahepatic cholangiocarcinoma: carcinogenesis of perihilar type and aggressive behavior of peripheral type. (21412073)
2011
25
Radiofrequency ablation for intrahepatic cholangiocarcinoma: retrospective analysis of a single centre experience. (22199333)
2011
26
Radiofrequency ablation of intrahepatic cholangiocarcinoma: preliminary experience. (20411389)
2010
27
Yttrium-90 radiotherapy for unresectable intrahepatic cholangiocarcinoma: a preliminary assessment of this novel treatment option. (19876691)
2010
28
Large Intrahepatic Cholangiocarcinoma with Tumor Infiltrative Lymphocytes and Autoimmune Hepatitis-Like Features. (21103227)
2010
29
Does intrahepatic cholangiocarcinoma have better prognosis compared to perihilar cholangiocarcinoma? (19953578)
2010
30
Clinical presentation and management of intrahepatic cholangiocarcinoma. (20202770)
2010
31
Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. (20545696)
2010
32
The prognosis and survival outcome of intrahepatic cholangiocarcinoma following surgical resection: association of lymph node metastasis and lymph node dissection with survival. (19626372)
2009
33
Relationship between microvessel count and postoperative survival in patients with intrahepatic cholangiocarcinoma. (19434454)
2009
34
Clinical characteristics of intrahepatic cholangiocarcinoma and prognostic factors in patients who received non-surgical treatment]. (19844142)
2009
35
A comprehensive analysis of immunohistochemical studies in intrahepatic cholangiocarcinoma using the survival tree model. (19262069)
2009
36
Immunohistochemically detected expression of p27(Kip1) and Skp2 predicts survival in patients with intrahepatic cholangiocarcinomas. (19034576)
2009
37
OEM-TACE: a new therapeutic approach in unresectable intrahepatic cholangiocarcinoma. (19727937)
2009
38
Clinicopathological analysis of colorectal cancer liver metastasis and intrahepatic cholangiocarcinoma: are they just apples and oranges? (18329969)
2008
39
Serum cytokeratin 19 fragment (CYFRA21-1) as a prognostic factor in intrahepatic cholangiocarcinoma. (17955299)
2008
40
Aberrant expression of alpha-fetoprotein in intrahepatic cholangiocarcinoma: an exceptional occurrence. (18417680)
2008
41
Influence of hepatic resection margin on recurrence and survival in intrahepatic cholangiocarcinoma. (18685896)
2008
42
Indications for surgical treatment of intrahepatic cholangiocarcinoma with lymph node metastases. (18670844)
2008
43
14-3-3sigma negatively regulates the cell cycle, and its down-regulation is associated with poor outcome in intrahepatic cholangiocarcinoma. (17391729)
2007
44
Comparison of combined hepatocellular and cholangiocarcinoma with hepatocellular carcinoma and intrahepatic cholangiocarcinoma. (16998683)
2006
45
Evaluation of CT during arterial portography for preoperative diagnosis of intrahepatic cholangiocarcinoma. (16795987)
2006
46
Intrahepatic cholangiocarcinoma with lymph node metastasis successfully treated by immunotherapy with CD3-activated T cells and dendritic cells after surgery: report of a case. (16715430)
2006
47
MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma. (16124042)
2005
48
Characterization of intrahepatic cholangiocarcinoma of the intraductal growth-type and its precursor lesions. (16116640)
2005
49
Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma. (12213730)
2002
50
Intrahepatic cholangiocarcinoma with lymphoepithelioma-like component. (11353065)
2001

Variations for Intrahepatic Cholangiocarcinoma

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Expression for genes affiliated with Intrahepatic Cholangiocarcinoma

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Expression patterns in normal tissues for genes affiliated with Intrahepatic Cholangiocarcinoma

Search GEO for disease gene expression data for Intrahepatic Cholangiocarcinoma.

Pathways for genes affiliated with Intrahepatic Cholangiocarcinoma

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Compounds for genes affiliated with Intrahepatic Cholangiocarcinoma

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GO Terms for genes affiliated with Intrahepatic Cholangiocarcinoma

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Products for genes affiliated with Intrahepatic Cholangiocarcinoma

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Sources for Intrahepatic Cholangiocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet