MCID: INT004
MIFTS: 33

Intraneural Perineurioma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Intraneural Perineurioma

Aliases & Descriptions for Intraneural Perineurioma:

Name: Intraneural Perineurioma 12 50 56 14 69

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4696
NCIt 47 C6911
SNOMED-CT 64 128795001
Orphanet 56 ORPHA100003
UMLS via Orphanet 70 C1370658
UMLS 69 C1370658

Summaries for Intraneural Perineurioma

MalaCards based summary : Intraneural Perineurioma is related to lucey-driscoll syndrome and secondary pulmonary hemosiderosis. An important gene associated with Intraneural Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Affiliated tissues include tongue and skin, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and cellular

Wikipedia : 71 An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but... more...

Related Diseases for Intraneural Perineurioma

Diseases related to Intraneural Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
id Related Disease Score Top Affiliating Genes
1 lucey-driscoll syndrome 10.4 MUC1 S100B
2 secondary pulmonary hemosiderosis 10.4 MUC1 S100B
3 infiltrating lipoma 10.4 S100A1 S100B
4 myelinoclastic diffuse sclerosis 10.3 MUC1 S100B
5 invasive mole 10.3 MUC1 S100B
6 maxillary sinus schneiderian papilloma 10.3 KRT13 KRT5
7 extrahepatic cholestasis 10.3 KRT13 KRT5
8 subglottis verrucous carcinoma 10.3 KRT10 MUC1 S100B
9 occipital encephalocele 10.3 KRT18 KRT8
10 clear cell ependymoma 10.3 MUC1 S100B SOX10
11 adult central nervous system choriocarcinoma 10.3 S100A1 SLC2A1
12 conjunctival cancer 10.3 KRT14 MUC1 S100B
13 popliteal pterygium syndrome, bartsocas-papas type 10.3 MUC1 S100A1 S100B
14 evc-related ellis-van creveld syndrome 10.3 KRT14 KRT5
15 woolly hair, autosomal dominant 10.3 KRT18 KRT8
16 pachyonychia congenita 4 10.3 KRT14 KRT5
17 mediastinum liposarcoma 10.3 KRT8 MUC1 S100B
18 epidermylysis bullosa simplex-mcr 10.3 KRT14 KRT5
19 adult mesoblastic nephroma 10.3 KRT13 KRT18
20 trombiculiasis 10.3 MUC1 NF1 S100B
21 cauda equina intradural extramedullary astrocytoma 10.3 KRT14 KRT18 MUC1
22 mediastinum angiosarcoma 10.2 KRT14 MUC1 S100B
23 prolactin producing pituitary tumor 10.2 KRT5 MUC1
24 thymus squamous cell carcinoma 10.2 KRT13 KRT14 KRT8
25 pediculus humanus corporis infestation 10.2 KRT18 KRT8 S100B
26 multidrug-resistant tuberculosis 10.2 KRT18 KRT5
27 mixed cell adenoma 10.2 KRT10 KRT14 KRT5
28 dowling-degos disease 1 10.2 KRT10 KRT14 KRT5
29 basaloid squamous cell carcinoma 10.2 KRT10 KRT14 KRT5
30 myoma 10.2 MUC1 S100B
31 central nervous system hemangioma 10.2 MUC1 NF1 S100B
32 vascular dementia 10.2 KRT10 KRT13 KRT14
33 clear cell cystadenofibroma 10.2 KRT14 KRT5 KRT8
34 granular cell leiomyosarcoma 10.2 KRT8 MUC1 S100B SLC2A1
35 scott syndrome 10.2 KRT10 KRT14 KRT5
36 intrahepatic bile duct cystadenoma 10.2 NF1 S100B
37 skin papilloma 10.2 KRT13 KRT14 KRT5
38 pemphigus vegetans 10.2 MUC1 S100B
39 c-p angle neurinoma 10.2 NF1 S100B SOX10
40 ovarian insufficiency due to fsh resistance 10.2 KRT5 MUC1 NF1
41 vulva adenocarcinoma 10.2 KRT14 KRT5 KRT8
42 intraocular retinoblastoma 10.2 KRT10 KRT14 KRT5
43 ovarian embryonal carcinoma 10.2 ALK KRT18 KRT8
44 sed congenita 10.2 KRT14 KRT5
45 bone chondrosarcoma 10.2 KRT14 KRT18 KRT8
46 dissociative amnesia 10.2 KRT19 KRT8
47 envenomization by bothrops lanceolatus 10.2 KRT7 KRT8
48 vulvar angiokeratoma 10.2 KRT10 KRT7 MUC1
49 suppurative lymphadenitis 10.2 KRT5 KRT7
50 anus adenocarcinoma 10.2 KRT14 KRT18 KRT8 MUC1

Graphical network of the top 20 diseases related to Intraneural Perineurioma:



Diseases related to Intraneural Perineurioma

Symptoms & Phenotypes for Intraneural Perineurioma

GenomeRNAi Phenotypes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.58 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.58 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.58 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.58 KRT8 KRT5
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.58 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.58 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.58 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.58 KRT7
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.58 KRT7 KRT8 KRT18 KRT5
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.58 KRT7
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.58 KRT18
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.58 KRT7 KRT5

MGI Mouse Phenotypes related to Intraneural Perineurioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.96 CD34 KRT14 KRT19 KRT7 NF1 PEG10
2 growth/size/body region MP:0005378 9.9 KRT19 KRT5 KRT8 NF1 PEG10 PMP22
3 integument MP:0010771 9.56 ALK CD34 KRT14 KRT19 KRT5 NF1
4 neoplasm MP:0002006 9.1 ALK CD34 KRT14 KRT19 NF1 SOX10

Drugs & Therapeutics for Intraneural Perineurioma

Search Clinical Trials , NIH Clinical Center for Intraneural Perineurioma

Genetic Tests for Intraneural Perineurioma

Anatomical Context for Intraneural Perineurioma

MalaCards organs/tissues related to Intraneural Perineurioma:

39
Tongue, Skin

Publications for Intraneural Perineurioma

Articles related to Intraneural Perineurioma:

(show all 42)
id Title Authors Year
1
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. ( 27525083 )
2016
2
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. ( 27001989 )
2016
3
Intratemporal Intraneural Perineurioma of the Facial Nerve. ( 27668794 )
2016
4
Intraneural perineurioma of the digital nerve: a case report. ( 26115680 )
2015
5
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. ( 24883285 )
2014
6
Intraneural Perineurioma of the Skin. ( 24999546 )
2014
7
Distinctive manifestations of cutaneous intraneural perineurioma of fingers, compared with typical intraneural perineurioma. ( 24685866 )
2014
8
Intraneural perineurioma affecting multiple nerves: a case report and literature review. ( 25031759 )
2014
9
Cutaneous intraneural perineurioma: a case report. ( 23221470 )
2013
10
Hybrid schwannoma/perineurioma of the spinal nerve: multifocal occurrence, and recurrence as an intraneural perineurioma. ( 23865576 )
2013
11
Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy. ( 24263031 )
2013
12
Intraneural perineurioma of the sciatic nerve: An under-recognized nerve neoplasm with characteristic MRI findings. ( 24061494 )
2013
13
Intraneural perineurioma arising in the lateral border of the tongue. ( 24422960 )
2013
14
Claudin-1 and glucose transporter 1 immunolabelling in a canine intraneural perineurioma. ( 22297071 )
2012
15
MRI of intraneural perineurioma of the brachial plexus. ( 27326273 )
2012
16
Mini-invasive robot-assisted surgery of the brachial plexus: a case of intraneural perineurioma. ( 22638873 )
2012
17
Intraneural perineurioma of the median nerve: case report and literature review. ( 19876692 )
2010
18
A case of intraneural perineurioma presenting with monomelic atrophy in a child. ( 20004070 )
2010
19
Oral intraneural perineurioma. Report of two cases. ( 19841714 )
2009
20
Intraneural perineurioma. ( 19766004 )
2009
21
Longitudinal study of intraneural perineurioma--a benign, focal hypertrophic neuropathy of youth. ( 19567701 )
2009
22
Intraneural perineurioma of the sciatic nerve in early childhood. ( 19520281 )
2009
23
Re: intraneural perineurioma of the median nerve. A rare cause of carpal tunnel syndrome. ( 18332033 )
2008
24
Intraneural perineurioma: a systematic review with illustrative cases. ( 17824794 )
2007
25
Intraneural perineurioma of the oral mucosa. ( 16757071 )
2007
26
Multiple orofacial intraneural perineuriomas in a patient with hemifacial hyperplasia. ( 17449293 )
2007
27
Intraneural perineurioma of the radial nerve visualized by 3.0 Tesla MRI. ( 17471567 )
2007
28
Intraneural perineurioma of the VIIIth cranial nerve: case report. ( 17881938 )
2007
29
Intraneural perineurioma of the tongue: a case report. ( 16781350 )
2006
30
Canine intraneural perineurioma. ( 16407486 )
2006
31
Intraneural perineurioma of the third cranial nerve: occurrence and identification. Case report. ( 16703891 )
2006
32
Intraneural perineurioma of the radial nerve in a child. ( 16039379 )
2005
33
Intraneural perineurioma in a child with Beckwith-Wiedemann syndrome. ( 15750909 )
2005
34
Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow. ( 15266642 )
2004
35
Intraosseous intraneural perineurioma: report of a case with morphological, immunohistochemical and FISH study. ( 14704619 )
2004
36
Intraneural perineurioma involving the ulnar nerve. ( 15086844 )
2004
37
Radial nerve palsy owing to localized hypertrophic neuropathy (intraneural perineurioma) in early childhood. ( 15032391 )
2004
38
Intraneural perineurioma--not restricted to major nerves. ( 12931092 )
2003
39
Intraneural perineurioma of the common peroneal nerve. Case report and review of the literature. ( 11354415 )
2001
40
Carpal tunnel syndrome due to an intraneural perineurioma in a 2-year-old child. ( 11281674 )
2001
41
Intraneural perineurioma involving the median nerve. ( 10839408 )
2000
42
Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22. ( 7785653 )
1995

Variations for Intraneural Perineurioma

Expression for Intraneural Perineurioma

Search GEO for disease gene expression data for Intraneural Perineurioma.

Pathways for Intraneural Perineurioma

Pathways related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 KRT10 KRT13 KRT14 KRT18 KRT19 KRT5
2 12.24 KRT10 KRT13 KRT18 KRT19 KRT5 KRT7
3
Show member pathways
12.01 KRT10 KRT13 KRT14 KRT18 KRT19 KRT5
4 11.4 S100B SLC2A1 SOX10
5
Show member pathways
11.2 KRT13 KRT14 KRT18 KRT19 KRT5 KRT7

GO Terms for Intraneural Perineurioma

Cellular components related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 9.55 CD34 KRT14 KRT18 KRT19 KRT8
2 keratin filament GO:0045095 9.43 KRT13 KRT14 KRT18 KRT5 KRT7 KRT8
3 dystrophin-associated glycoprotein complex GO:0016010 9.37 KRT19 KRT8
4 intermediate filament GO:0005882 9.23 KRT10 KRT13 KRT14 KRT18 KRT19 KRT5
5 cytoplasm GO:0005737 10.17 CD34 KRT10 KRT14 KRT18 KRT5 KRT7
6 extracellular exosome GO:0070062 10 ALK KRT10 KRT13 KRT14 KRT18 KRT19

Biological processes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.56 KRT10 KRT13 KRT14 KRT18 KRT19 KRT5
2 hepatocyte apoptotic process GO:0097284 9.37 KRT18 KRT8
3 peripheral nervous system development GO:0007422 9.33 NF1 PMP22 SOX10
4 hemidesmosome assembly GO:0031581 9.32 KRT14 KRT5
5 cell differentiation involved in embryonic placenta development GO:0060706 9.26 KRT19 KRT8
6 cornification GO:0070268 9.23 KRT10 KRT13 KRT14 KRT18 KRT19 KRT5

Molecular functions related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 9.5 KRT14 KRT19 KRT5
2 structural molecule activity GO:0005198 9.26 KRT13 KRT18 KRT7 KRT8
3 S100 protein binding GO:0044548 9.16 S100A1 S100B
4 scaffold protein binding GO:0097110 8.8 KRT18 KRT5 KRT8
5 protein binding GO:0005515 10.16 ALK KRT13 KRT14 KRT18 KRT19 KRT5

Sources for Intraneural Perineurioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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