MCID: INT004
MIFTS: 33

Intraneural Perineurioma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Intraneural Perineurioma

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Aliases & Descriptions for Intraneural Perineurioma:

Name: Intraneural Perineurioma 11 47 53 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:4696
NCIt44 C6911
SNOMED-CT61 128795001
Orphanet53 ORPHA100003
UMLS via Orphanet68 C1370658

Summaries for Intraneural Perineurioma

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Wikipedia:70 An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but... more...

MalaCards based summary: Intraneural Perineurioma is related to 2q33.1 microdeletion syndrome and logopenic progressive aphasia. An important gene associated with Intraneural Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Cytoskeletal Signaling. Affiliated tissues include tongue and skin, and related mouse phenotypes are integument and neoplasm.

Related Diseases for Intraneural Perineurioma

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Diseases related to Intraneural Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 154)
idRelated DiseaseScoreTop Affiliating Genes
12q33.1 microdeletion syndrome10.8MUC1, S100A1
2logopenic progressive aphasia10.8MUC1, S100B
3intermediate dend syndrome10.8MUC1, S100B
4lyme disease - neurological complications10.8MUC1, S100B
5anaplastic oligoastrocytoma10.8MUC1, S100B
6relapsing epidemic typhus10.7MUC1, S100B
7intermediate cell type ciliary body melanoma10.7S100A1, S100B
8endobronchial leiomyoma10.7S100A1, SLC2A1
9lymphangiosarcoma10.7MUC1, S100B
10pituitary deficiency due to rathke's pouch cysts10.7MUC1, S100B
11chondroblastoma10.7MUC1, S100B
12iris disease10.7KRT13, MUC1
13perineurioma10.7
14subacute leukemia10.7MUC1, S100B
15pediculus humanus capitis infestation10.7MUC1, S100B
16lumbar plexus neoplasm10.6MUC1, S100B
17epicardium cancer10.6MUC1, S100B, SLC2A1
18carotid artery occlusion10.6KRT13, KRT5
19biliary atresia10.6KRT13, KRT5
20external ear disease10.6MUC1, S100B
21clear cell adenoma10.6KRT5, MUC1
22polyomavirus allograft nephropathy10.6MUC1, S100A1, S100B
23placental site trophoblastic tumor10.6KRT18, MUC1
24short stature-deafness-neutrophil dysfunction-dysmorphism syndrome10.6KRT18, KRT8
25subependymal giant cell astrocytoma10.6MUC1, S100B
26pachyonychia congenita 310.6KRT14, KRT5
27hypotrichosis 1310.6KRT18, KRT8
28bartholin's gland benign neoplasm10.6KRT14, MUC1, S100B
29dowling-degos disease 110.6KRT14, KRT5
30eccrine papillary adenoma10.6KRT14, MUC1, S100B
31hidradenoma10.6KRT8, SOX10
32sclerosing liposarcoma10.6KRT8, MUC1, S100B
33quinquaud's decalvans folliculitis10.5KRT14, KRT5
34penis verrucous carcinoma10.5MUC1, S100B
35cervix endometrial stromal tumor10.5KRT14, MUC1, S100B
36metatypical basal cell carcinoma10.5KRT10, KRT14
37diffuse large b-cell lymphoma with chronic inflammation10.5ALK, MUC1
38congenital sucrase-isomaltase deficiency with starch intolerance10.5ALK, MUC1
39sed congenita10.5KRT14, KRT5
40malignant cystic nephroma10.5KRT10, KRT5, S100B
41subacute monocytic leukemia10.5KRT10, KRT13, KRT14
42vascular hemostatic disease10.5KRT14, KRT18, MUC1
43pseudoglandular variant testicular seminoma10.5MUC1, NF1, S100B
44anal squamous cell carcinoma10.4KRT13, KRT14, KRT8
45adenomyoma of uterine corpus10.4MUC1, NF1, S100B
46pemphigus vulgaris, familial10.4KRT7, MUC1
47hemoglobin d disease10.4KRT10, KRT14, KRT5
48gastric squamous cell carcinoma10.4KRT10, KRT14, KRT5
49epidermolysis bullosa simplex-mp10.4KRT10, KRT14, KRT5
50plethora of newborn10.4KRT7, MUC1

Graphical network of the top 20 diseases related to Intraneural Perineurioma:



Diseases related to intraneural perineurioma

Symptoms for Intraneural Perineurioma

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Drugs & Therapeutics for Intraneural Perineurioma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Intraneural Perineurioma

Genetic Tests for Intraneural Perineurioma

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Anatomical Context for Intraneural Perineurioma

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MalaCards organs/tissues related to Intraneural Perineurioma:

35
Tongue, Skin

Animal Models for Intraneural Perineurioma or affiliated genes

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MGI Mouse Phenotypes related to Intraneural Perineurioma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.0ALK, CD34, KRT14, KRT19, KRT5, NF1
2MP:00020067.8ALK, CD34, KRT14, KRT19, NF1, SOX10
3MP:00053787.6ALK, KRT14, KRT18, KRT19, KRT5, KRT8
4MP:00053847.2CD34, KRT14, KRT19, KRT7, NF1, PEG10

Publications for Intraneural Perineurioma

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Articles related to Intraneural Perineurioma:

(show all 42)
idTitleAuthorsYear
1
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. (27001989)
2016
2
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. (27525083)
2016
3
Intratemporal Intraneural Perineurioma of the Facial Nerve. (27668794)
2016
4
Intraneural perineurioma of the digital nerve: a case report. (26115680)
2015
5
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. (24883285)
2014
6
Intraneural perineurioma affecting multiple nerves: a case report and literature review. (25031759)
2014
7
Distinctive manifestations of cutaneous intraneural perineurioma of fingers, compared with typical intraneural perineurioma. (24685866)
2014
8
Intraneural Perineurioma of the Skin. (24999546)
2014
9
Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy. (24263031)
2013
10
Intraneural perineurioma of the sciatic nerve: An under-recognized nerve neoplasm with characteristic MRI findings. (24061494)
2013
11
Cutaneous intraneural perineurioma: a case report. (23221470)
2013
12
Hybrid schwannoma/perineurioma of the spinal nerve: multifocal occurrence, and recurrence as an intraneural perineurioma. (23865576)
2013
13
Intraneural perineurioma arising in the lateral border of the tongue. (24422960)
2013
14
Claudin-1 and glucose transporter 1 immunolabelling in a canine intraneural perineurioma. (22297071)
2012
15
MRI of intraneural perineurioma of the brachial plexus. (27326273)
2012
16
Mini-invasive robot-assisted surgery of the brachial plexus: a case of intraneural perineurioma. (22638873)
2012
17
A case of intraneural perineurioma presenting with monomelic atrophy in a child. (20004070)
2010
18
Intraneural perineurioma of the median nerve: case report and literature review. (19876692)
2010
19
Intraneural perineurioma. (19766004)
2009
20
Intraneural perineurioma of the sciatic nerve in early childhood. (19520281)
2009
21
Longitudinal study of intraneural perineurioma--a benign, focal hypertrophic neuropathy of youth. (19567701)
2009
22
Oral intraneural perineurioma. Report of two cases. (19841714)
2009
23
Re: intraneural perineurioma of the median nerve. A rare cause of carpal tunnel syndrome. (18332033)
2008
24
Intraneural perineurioma of the radial nerve visualized by 3.0 Tesla MRI. (17471567)
2007
25
Intraneural perineurioma of the VIIIth cranial nerve: case report. (17881938)
2007
26
Intraneural perineurioma: a systematic review with illustrative cases. (17824794)
2007
27
Multiple orofacial intraneural perineuriomas in a patient with hemifacial hyperplasia. (17449293)
2007
28
Intraneural perineurioma of the oral mucosa. (16757071)
2007
29
Canine intraneural perineurioma. (16407486)
2006
30
Intraneural perineurioma of the tongue: a case report. (16781350)
2006
31
Intraneural perineurioma of the third cranial nerve: occurrence and identification. Case report. (16703891)
2006
32
Intraneural perineurioma of the radial nerve in a child. (16039379)
2005
33
Intraneural perineurioma in a child with Beckwith-Wiedemann syndrome. (15750909)
2005
34
Radial nerve palsy owing to localized hypertrophic neuropathy (intraneural perineurioma) in early childhood. (15032391)
2004
35
Intraosseous intraneural perineurioma: report of a case with morphological, immunohistochemical and FISH study. (14704619)
2004
36
Intraneural perineurioma involving the ulnar nerve. (15086844)
2004
37
Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow. (15266642)
2004
38
Intraneural perineurioma--not restricted to major nerves. (12931092)
2003
39
Carpal tunnel syndrome due to an intraneural perineurioma in a 2-year-old child. (11281674)
2001
40
Intraneural perineurioma of the common peroneal nerve. Case report and review of the literature. (11354415)
2001
41
Intraneural perineurioma involving the median nerve. (10839408)
2000
42
Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22. (7785653)
1995

Variations for Intraneural Perineurioma

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Expression for genes affiliated with Intraneural Perineurioma

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Search GEO for disease gene expression data for Intraneural Perineurioma.

Pathways for genes affiliated with Intraneural Perineurioma

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Pathways related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8S100B, SLC2A1, SOX10
28.0KRT10, KRT13, KRT18, KRT19, KRT5, KRT7
3
Show member pathways
7.9KRT13, KRT14, KRT18, KRT19, KRT5, KRT7

GO Terms for genes affiliated with Intraneural Perineurioma

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Cellular components related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1costamereGO:004303410.0KRT19, KRT8
2dystrophin-associated glycoprotein complexGO:001601010.0KRT19, KRT8
3Z discGO:00300189.5KRT19, KRT8, S100A1
4keratin filamentGO:00450959.2KRT13, KRT14, KRT18, KRT5, KRT7, KRT8
5cell peripheryGO:00719448.7CD34, KRT14, KRT18, KRT19, KRT8
6intermediate filamentGO:00058828.5KRT10, KRT14, KRT18, KRT19, KRT5, KRT7
7extracellular exosomeGO:00700626.7ALK, KRT10, KRT13, KRT14, KRT18, KRT19
8cytoplasmGO:00057375.6CD34, KRT10, KRT14, KRT18, KRT5, KRT7

Biological processes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell differentiation involved in embryonic placenta developmentGO:00607069.9KRT19, KRT8
2hepatocyte apoptotic processGO:00972849.9KRT18, KRT8
3hemidesmosome assemblyGO:00315819.6KRT14, KRT5
4peripheral nervous system developmentGO:00074229.5NF1, PMP22, SOX10

Molecular functions related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:004454810.3S100A1, S100B
2scaffold protein bindingGO:00971109.3KRT18, KRT5, KRT8
3structural constituent of cytoskeletonGO:00052009.3KRT14, KRT19, KRT5
4structural molecule activityGO:00051989.2KRT13, KRT18, KRT7, KRT8

Sources for Intraneural Perineurioma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet