MCID: INT004
MIFTS: 33

Intraneural Perineurioma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Intraneural Perineurioma

About this section

Aliases & Descriptions for Intraneural Perineurioma:

Name: Intraneural Perineurioma 11 46 13 52 66

Classifications:



External Ids:

Disease Ontology11 DOID:4696
NCIt43 C6911
SNOMED-CT60 128795001
Orphanet52 ORPHA100003
UMLS via Orphanet67 C1370658

Summaries for Intraneural Perineurioma

About this section
Wikipedia:69 An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but... more...

MalaCards based summary: Intraneural Perineurioma is related to 2q33.1 microdeletion syndrome and logopenic progressive aphasia. An important gene associated with Intraneural Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Cytoskeletal Signaling. Affiliated tissues include tongue and skin, and related mouse phenotype growth/size/body region.

Related Diseases for Intraneural Perineurioma

About this section

Diseases related to Intraneural Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
12q33.1 microdeletion syndrome10.9MUC1, S100A1
2logopenic progressive aphasia10.9MUC1, S100B
3intermediate dend syndrome10.9MUC1, S100B
4lyme disease - neurological complications10.9MUC1, S100B
5anaplastic oligoastrocytoma10.9MUC1, S100B
6relapsing epidemic typhus10.9MUC1, S100B
7intermediate cell type ciliary body melanoma10.9S100A1, S100B
8endobronchial leiomyoma10.8S100A1, SLC2A1
9lymphangiosarcoma10.8MUC1, S100B
10pituitary deficiency due to rathke's pouch cysts10.8MUC1, S100B
11intravascular fasciitis10.8MUC1, S100A1
12chondroblastoma10.8MUC1, S100B
13perineurioma10.8
14iris disease10.8KRT13, MUC1
15subacute leukemia10.8MUC1, S100B
16pediculus humanus capitis infestation10.8MUC1, S100B
17lumbar plexus neoplasm10.8MUC1, S100B
18external ear disease10.8MUC1, S100B
19subependymal giant cell astrocytoma10.7MUC1, S100B
20penis verrucous carcinoma10.7MUC1, S100B
21epicardium cancer10.7MUC1, S100B, SLC2A1
22carotid artery occlusion10.7KRT13, KRT5
23placental site trophoblastic tumor10.7KRT18, MUC1
24clear cell adenoma10.7KRT5, MUC1
25biliary atresia10.7KRT13, KRT5
26polyomavirus allograft nephropathy10.7MUC1, S100A1, S100B
27hidradenoma10.7KRT8, SOX10
28breast papillary carcinoma10.7MUC1, S100B
29short stature-deafness-neutrophil dysfunction-dysmorphism syndrome10.7KRT18, KRT8
30pachyonychia congenita 310.6KRT14, KRT5
31hypotrichosis 1310.6KRT18, KRT8
32bartholin's gland benign neoplasm10.6KRT14, MUC1, S100B
33eccrine papillary adenoma10.6KRT14, MUC1, S100B
34dowling-degos disease 110.6KRT14, KRT5
35sclerosing liposarcoma10.6KRT8, MUC1, S100B
36metatypical basal cell carcinoma10.6KRT10, KRT14
37quinquaud's decalvans folliculitis10.6KRT14, KRT5
38gallbladder adenoma10.6MUC1, S100B
39cerebrovascular disease10.6NF1, S100B
40diffuse large b-cell lymphoma with chronic inflammation10.6ALK, MUC1
41cervix endometrial stromal tumor10.6KRT14, MUC1, S100B
42congenital sucrase-isomaltase deficiency with starch intolerance10.6ALK, MUC1
43skin glomangioma10.6MUC1, S100B
44urinary bladder urothelial carcinoma10.6KRT18, KRT5
45bronchial neoplasm10.6KRT5, MUC1
46sed congenita10.6KRT14, KRT5
47pemphigus vulgaris, familial10.5KRT7, MUC1
48subacute monocytic leukemia10.5KRT10, KRT13, KRT14
49vascular hemostatic disease10.5KRT14, KRT18, MUC1
50malignant cystic nephroma10.5KRT10, KRT5, S100B

Graphical network of the top 20 diseases related to Intraneural Perineurioma:



Diseases related to intraneural perineurioma

Symptoms for Intraneural Perineurioma

About this section

Drugs & Therapeutics for Intraneural Perineurioma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Intraneural Perineurioma

Genetic Tests for Intraneural Perineurioma

About this section

Anatomical Context for Intraneural Perineurioma

About this section

MalaCards organs/tissues related to Intraneural Perineurioma:

34
Tongue, Skin

Animal Models for Intraneural Perineurioma or affiliated genes

About this section

MGI Mouse Phenotypes related to Intraneural Perineurioma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053786.5ALK, KRT14, KRT18, KRT19, KRT5, KRT8

Publications for Intraneural Perineurioma

About this section

Articles related to Intraneural Perineurioma:

(show all 41)
idTitleAuthorsYear
1
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. (27001989)
2016
2
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. (27525083)
2016
3
Intraneural perineurioma of the digital nerve: a case report. (26115680)
2015
4
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. (24883285)
2014
5
Intraneural perineurioma affecting multiple nerves: a case report and literature review. (25031759)
2014
6
Distinctive manifestations of cutaneous intraneural perineurioma of fingers, compared with typical intraneural perineurioma. (24685866)
2014
7
Intraneural Perineurioma of the Skin. (24999546)
2014
8
Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy. (24263031)
2013
9
Intraneural perineurioma of the sciatic nerve: An under-recognized nerve neoplasm with characteristic MRI findings. (24061494)
2013
10
Cutaneous intraneural perineurioma: a case report. (23221470)
2013
11
Hybrid schwannoma/perineurioma of the spinal nerve: multifocal occurrence, and recurrence as an intraneural perineurioma. (23865576)
2013
12
Intraneural perineurioma arising in the lateral border of the tongue. (24422960)
2013
13
Claudin-1 and glucose transporter 1 immunolabelling in a canine intraneural perineurioma. (22297071)
2012
14
MRI of intraneural perineurioma of the brachial plexus. (27326273)
2012
15
Mini-invasive robot-assisted surgery of the brachial plexus: a case of intraneural perineurioma. (22638873)
2012
16
A case of intraneural perineurioma presenting with monomelic atrophy in a child. (20004070)
2010
17
Intraneural perineurioma of the median nerve: case report and literature review. (19876692)
2010
18
Intraneural perineurioma. (19766004)
2009
19
Intraneural perineurioma of the sciatic nerve in early childhood. (19520281)
2009
20
Longitudinal study of intraneural perineurioma--a benign, focal hypertrophic neuropathy of youth. (19567701)
2009
21
Oral intraneural perineurioma. Report of two cases. (19841714)
2009
22
Re: intraneural perineurioma of the median nerve. A rare cause of carpal tunnel syndrome. (18332033)
2008
23
Intraneural perineurioma of the radial nerve visualized by 3.0 Tesla MRI. (17471567)
2007
24
Intraneural perineurioma of the VIIIth cranial nerve: case report. (17881938)
2007
25
Intraneural perineurioma: a systematic review with illustrative cases. (17824794)
2007
26
Multiple orofacial intraneural perineuriomas in a patient with hemifacial hyperplasia. (17449293)
2007
27
Intraneural perineurioma of the oral mucosa. (16757071)
2007
28
Canine intraneural perineurioma. (16407486)
2006
29
Intraneural perineurioma of the tongue: a case report. (16781350)
2006
30
Intraneural perineurioma of the third cranial nerve: occurrence and identification. Case report. (16703891)
2006
31
Intraneural perineurioma of the radial nerve in a child. (16039379)
2005
32
Intraneural perineurioma in a child with Beckwith-Wiedemann syndrome. (15750909)
2005
33
Radial nerve palsy owing to localized hypertrophic neuropathy (intraneural perineurioma) in early childhood. (15032391)
2004
34
Intraosseous intraneural perineurioma: report of a case with morphological, immunohistochemical and FISH study. (14704619)
2004
35
Intraneural perineurioma involving the ulnar nerve. (15086844)
2004
36
Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow. (15266642)
2004
37
Intraneural perineurioma--not restricted to major nerves. (12931092)
2003
38
Carpal tunnel syndrome due to an intraneural perineurioma in a 2-year-old child. (11281674)
2001
39
Intraneural perineurioma of the common peroneal nerve. Case report and review of the literature. (11354415)
2001
40
Intraneural perineurioma involving the median nerve. (10839408)
2000
41
Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22. (7785653)
1995

Variations for Intraneural Perineurioma

About this section

Expression for genes affiliated with Intraneural Perineurioma

About this section
Search GEO for disease gene expression data for Intraneural Perineurioma.

Pathways for genes affiliated with Intraneural Perineurioma

About this section

Pathways related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8S100B, SLC2A1, SOX10
27.7KRT10, KRT13, KRT18, KRT19, KRT5, KRT7
3
Show member pathways
7.7KRT13, KRT14, KRT18, KRT19, KRT5, KRT7

GO Terms for genes affiliated with Intraneural Perineurioma

About this section

Cellular components related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dystrophin-associated glycoprotein complexGO:00160109.9KRT19, KRT8
2costamereGO:00430349.9KRT19, KRT8
3Z discGO:00300189.4KRT19, KRT8, S100A1
4cell peripheryGO:00719449.3KRT14, KRT18, KRT19, KRT8
5keratin filamentGO:00450959.1KRT13, KRT14, KRT18, KRT5, KRT7, KRT8
6intermediate filamentGO:00058828.2KRT10, KRT14, KRT18, KRT19, KRT5, KRT7
7extracellular exosomeGO:00700626.7ALK, KRT10, KRT13, KRT14, KRT18, KRT19
8cytoplasmGO:00057376.2KRT10, KRT14, KRT18, KRT5, KRT7, KRT8

Biological processes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hemidesmosome assemblyGO:003158110.2KRT14, KRT5
2peripheral nervous system developmentGO:00074229.9NF1, PMP22, SOX10
3cell differentiation involved in embryonic placenta developmentGO:00607069.9KRT19, KRT8
4hepatocyte apoptotic processGO:00972849.9KRT18, KRT8
5viral processGO:00160328.2KRT18, KRT19, KRT7, KRT8

Molecular functions related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:004454810.5S100A1, S100B
2scaffold protein bindingGO:009711010.1KRT18, KRT5, KRT8
3structural molecule activityGO:00051989.7KRT13, KRT18, KRT7, KRT8
4structural constituent of cytoskeletonGO:00052009.5KRT14, KRT19, KRT5
5identical protein bindingGO:00428028.9ALK, S100A1, S100B, SLC2A1, SOX10
6protein bindingGO:00055154.7ALK, KRT13, KRT14, KRT18, KRT19, KRT5

Sources for Intraneural Perineurioma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet