MCID: INT004
MIFTS: 33

Intraneural Perineurioma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Intraneural Perineurioma

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Aliases & Descriptions for Intraneural Perineurioma:

Name: Intraneural Perineurioma 11 48 54 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:4696
NCIt45 C6911
SNOMED-CT62 128795001
Orphanet54 ORPHA100003
UMLS via Orphanet69 C1370658

Summaries for Intraneural Perineurioma

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Wikipedia:71 An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but... more...

MalaCards based summary: Intraneural Perineurioma is related to lucey-driscoll syndrome and secondary pulmonary hemosiderosis. An important gene associated with Intraneural Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include tongue and skin, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and integument.

Related Diseases for Intraneural Perineurioma

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Diseases related to Intraneural Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 128)
idRelated DiseaseScoreTop Affiliating Genes
1lucey-driscoll syndrome10.4MUC1, S100B
2secondary pulmonary hemosiderosis10.4MUC1, S100B
3infiltrating lipoma10.4S100A1, S100B
4myelinoclastic diffuse sclerosis10.3MUC1, S100B
5invasive mole10.3MUC1, S100B
6maxillary sinus schneiderian papilloma10.3KRT13, KRT5
7extrahepatic cholestasis10.3KRT13, KRT5
8subglottis verrucous carcinoma10.3KRT10, MUC1, S100B
9occipital encephalocele10.3KRT18, KRT8
10clear cell ependymoma10.3MUC1, S100B, SOX10
11adult central nervous system choriocarcinoma10.3S100A1, SLC2A1
12conjunctival cancer10.3KRT14, MUC1, S100B
13popliteal pterygium syndrome, bartsocas-papas type10.3MUC1, S100A1, S100B
14evc-related ellis-van creveld syndrome10.3KRT14, KRT5
15woolly hair, autosomal dominant10.3KRT18, KRT8
16pachyonychia congenita 410.3KRT14, KRT5
17mediastinum liposarcoma10.3KRT8, MUC1, S100B
18epidermylysis bullosa simplex-mcr10.3KRT14, KRT5
19adult mesoblastic nephroma10.3KRT13, KRT18
20trombiculiasis10.3MUC1, NF1, S100B
21cauda equina intradural extramedullary astrocytoma10.3KRT14, KRT18, MUC1
22mediastinum angiosarcoma10.2KRT14, MUC1, S100B
23prolactin producing pituitary tumor10.2KRT5, MUC1
24thymus squamous cell carcinoma10.2KRT13, KRT14, KRT8
25pediculus humanus corporis infestation10.2KRT18, KRT8, S100B
26multidrug-resistant tuberculosis10.2KRT18, KRT5
27mixed cell adenoma10.2KRT10, KRT14, KRT5
28dowling-degos disease 110.2KRT10, KRT14, KRT5
29basaloid squamous cell carcinoma10.2KRT10, KRT14, KRT5
30myoma10.2MUC1, S100B
31central nervous system hemangioma10.2MUC1, NF1, S100B
32vascular dementia10.2KRT10, KRT13, KRT14
33clear cell cystadenofibroma10.2KRT14, KRT5, KRT8
34granular cell leiomyosarcoma10.2KRT8, MUC1, S100B, SLC2A1
35scott syndrome10.2KRT10, KRT14, KRT5
36intrahepatic bile duct cystadenoma10.2NF1, S100B
37skin papilloma10.2KRT13, KRT14, KRT5
38pemphigus vegetans10.2MUC1, S100B
39c-p angle neurinoma10.2NF1, S100B, SOX10
40ovarian insufficiency due to fsh resistance10.2KRT5, MUC1, NF1
41vulva adenocarcinoma10.2KRT14, KRT5, KRT8
42intraocular retinoblastoma10.2KRT10, KRT14, KRT5
43ovarian embryonal carcinoma10.2ALK, KRT18, KRT8
44sed congenita10.2KRT14, KRT5
45bone chondrosarcoma10.2KRT14, KRT18, KRT8
46dissociative amnesia10.2KRT19, KRT8
47envenomization by bothrops lanceolatus10.2KRT7, KRT8
48vulvar angiokeratoma10.2KRT10, KRT7, MUC1
49suppurative lymphadenitis10.2KRT5, KRT7
50anus adenocarcinoma10.2KRT14, KRT18, KRT8, MUC1

Graphical network of the top 20 diseases related to Intraneural Perineurioma:



Diseases related to intraneural perineurioma

Symptoms & Phenotypes for Intraneural Perineurioma

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GenomeRNAi Phenotypes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.9KRT18, KRT5, KRT7, KRT8

MGI Mouse Phenotypes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.0ALK, CD34, KRT14, KRT19, KRT5, NF1
2MP:00020067.8ALK, CD34, KRT14, KRT19, NF1, SOX10
3MP:00053787.4ALK, KRT14, KRT18, KRT19, KRT5, KRT8
4MP:00053847.2CD34, KRT14, KRT19, KRT7, NF1, PEG10

Drugs & Therapeutics for Intraneural Perineurioma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Intraneural Perineurioma

Genetic Tests for Intraneural Perineurioma

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Anatomical Context for Intraneural Perineurioma

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MalaCards organs/tissues related to Intraneural Perineurioma:

36
Tongue, Skin

Publications for Intraneural Perineurioma

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Articles related to Intraneural Perineurioma:

(show all 42)
idTitleAuthorsYear
1
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. (27525083)
2016
2
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. (27001989)
2016
3
Intratemporal Intraneural Perineurioma of the Facial Nerve. (27668794)
2016
4
Intraneural perineurioma of the digital nerve: a case report. (26115680)
2015
5
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. (24883285)
2014
6
Intraneural Perineurioma of the Skin. (24999546)
2014
7
Distinctive manifestations of cutaneous intraneural perineurioma of fingers, compared with typical intraneural perineurioma. (24685866)
2014
8
Intraneural perineurioma affecting multiple nerves: a case report and literature review. (25031759)
2014
9
Cutaneous intraneural perineurioma: a case report. (23221470)
2013
10
Hybrid schwannoma/perineurioma of the spinal nerve: multifocal occurrence, and recurrence as an intraneural perineurioma. (23865576)
2013
11
Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy. (24263031)
2013
12
Intraneural perineurioma of the sciatic nerve: An under-recognized nerve neoplasm with characteristic MRI findings. (24061494)
2013
13
Intraneural perineurioma arising in the lateral border of the tongue. (24422960)
2013
14
Claudin-1 and glucose transporter 1 immunolabelling in a canine intraneural perineurioma. (22297071)
2012
15
MRI of intraneural perineurioma of the brachial plexus. (27326273)
2012
16
Mini-invasive robot-assisted surgery of the brachial plexus: a case of intraneural perineurioma. (22638873)
2012
17
Intraneural perineurioma of the median nerve: case report and literature review. (19876692)
2010
18
A case of intraneural perineurioma presenting with monomelic atrophy in a child. (20004070)
2010
19
Oral intraneural perineurioma. Report of two cases. (19841714)
2009
20
Intraneural perineurioma. (19766004)
2009
21
Longitudinal study of intraneural perineurioma--a benign, focal hypertrophic neuropathy of youth. (19567701)
2009
22
Intraneural perineurioma of the sciatic nerve in early childhood. (19520281)
2009
23
Re: intraneural perineurioma of the median nerve. A rare cause of carpal tunnel syndrome. (18332033)
2008
24
Intraneural perineurioma: a systematic review with illustrative cases. (17824794)
2007
25
Intraneural perineurioma of the oral mucosa. (16757071)
2007
26
Multiple orofacial intraneural perineuriomas in a patient with hemifacial hyperplasia. (17449293)
2007
27
Intraneural perineurioma of the radial nerve visualized by 3.0 Tesla MRI. (17471567)
2007
28
Intraneural perineurioma of the VIIIth cranial nerve: case report. (17881938)
2007
29
Intraneural perineurioma of the tongue: a case report. (16781350)
2006
30
Canine intraneural perineurioma. (16407486)
2006
31
Intraneural perineurioma of the third cranial nerve: occurrence and identification. Case report. (16703891)
2006
32
Intraneural perineurioma of the radial nerve in a child. (16039379)
2005
33
Intraneural perineurioma in a child with Beckwith-Wiedemann syndrome. (15750909)
2005
34
Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow. (15266642)
2004
35
Intraosseous intraneural perineurioma: report of a case with morphological, immunohistochemical and FISH study. (14704619)
2004
36
Intraneural perineurioma involving the ulnar nerve. (15086844)
2004
37
Radial nerve palsy owing to localized hypertrophic neuropathy (intraneural perineurioma) in early childhood. (15032391)
2004
38
Intraneural perineurioma--not restricted to major nerves. (12931092)
2003
39
Intraneural perineurioma of the common peroneal nerve. Case report and review of the literature. (11354415)
2001
40
Carpal tunnel syndrome due to an intraneural perineurioma in a 2-year-old child. (11281674)
2001
41
Intraneural perineurioma involving the median nerve. (10839408)
2000
42
Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22. (7785653)
1995

Variations for Intraneural Perineurioma

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Expression for genes affiliated with Intraneural Perineurioma

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Search GEO for disease gene expression data for Intraneural Perineurioma.

Pathways for genes affiliated with Intraneural Perineurioma

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GO Terms for genes affiliated with Intraneural Perineurioma

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Cellular components related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dystrophin-associated glycoprotein complexGO:001601010.3KRT19, KRT8
2cell peripheryGO:00719449.0CD34, KRT14, KRT18, KRT19, KRT8
3keratin filamentGO:00450958.6KRT13, KRT14, KRT18, KRT5, KRT7, KRT8
4intermediate filamentGO:00058828.2KRT10, KRT13, KRT14, KRT18, KRT19, KRT5
5extracellular exosomeGO:00700627.6ALK, KRT10, KRT13, KRT14, KRT18, KRT19
6cytoplasmGO:00057376.6CD34, KRT10, KRT14, KRT18, KRT5, KRT7

Biological processes related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hepatocyte apoptotic processGO:009728410.5KRT18, KRT8
2hemidesmosome assemblyGO:003158110.5KRT14, KRT5
3cell differentiation involved in embryonic placenta developmentGO:006070610.2KRT19, KRT8
4peripheral nervous system developmentGO:00074229.4NF1, PMP22, SOX10
5cornificationGO:00702688.3KRT10, KRT13, KRT14, KRT18, KRT19, KRT5
6keratinizationGO:00314248.1KRT10, KRT13, KRT14, KRT18, KRT19, KRT5

Molecular functions related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:004454810.7S100A1, S100B
2scaffold protein bindingGO:009711010.2KRT18, KRT5, KRT8
3structural constituent of cytoskeletonGO:00052009.9KRT14, KRT19, KRT5
4structural molecule activityGO:00051989.1KRT13, KRT18, KRT7, KRT8
5protein bindingGO:00055155.9ALK, KRT13, KRT14, KRT18, KRT19, KRT5

Sources for Intraneural Perineurioma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
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45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet