MCID: INT103
MIFTS: 35

Intrauterine Infections malady

Rare diseases category
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Summaries for Intrauterine Infections

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 A vertically transmitted infection is an infection caused by bacteria, viruses or, in rare cases,... more...

MalaCards: Intrauterine Infections is related to pseudo-torch syndrome and hepatitis b. An important gene associated with Intrauterine Infections is CLEC4M (C-type lectin domain family 4, member M), and among its related pathways are Influenza A and Tuberculosis. The compounds allergens and galactose have been mentioned in the context of this disorder. Affiliated tissues include eye, lung and ovary, and related mouse phenotypes are homeostasis/metabolism and tumorigenesis.

Aliases & Classifications for Intrauterine Infections

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43NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

intrauterine infections 43


Related Diseases for Intrauterine Infections

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Intrauterine Infections:



Diseases related to intrauterine infections

Symptoms for Intrauterine Infections

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Drugs & Therapeutics for Intrauterine Infections

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Intrauterine Infections

Search NIH Clinical Center for Intrauterine Infections

Genetic Tests for Intrauterine Infections

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Anatomical Context for Intrauterine Infections

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33MalaCards
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MalaCards organs/tissues related to Intrauterine Infections:

33
Eye, Lung, Ovary, Placenta, Cervix, B cells, Endothelial

Animal Models for Intrauterine Infections or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Intrauterine Infections:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.4CD209, DKC1, CLEC4M, TERC
2MP:00020068.2TERC, MMP8, DKC1
3MP:00053877.4CD209, DKC1, MMP8, CLEC4M, TERC

Publications for Intrauterine Infections

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52PubMed
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Articles related to Intrauterine Infections:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Relationship between intrauterine infection and the gene polymorphism of DC-SIGN/DC-SIGNR in the pregnant women of HBV positive]. (22338216)
2011
2
Activin A as a marker of intrauterine infection in women with preterm prelabour rupture of membranes. (19641514)
2010
3
Association between the frequency of class II HLA antigens and the susceptibility to intrauterine infection of hepatitis B virus. (18463715)
2008
4
Eye manifestations of intrauterine infections and their impact on childhood blindness. (18348876)
2008
5
Exodus-1 (CCL20): evidence for the participation of this chemokine in spontaneous labor at term, preterm labor, and intrauterine infection. (18576931)
2008
6
Evaluation levels of cytokines in amniotic fluid of women with intrauterine infection in the early second trimester. (16354974)
2006
7
The Alabama preterm birth study: corticosteroids and neonatal outcomes in 23- to 32-week newborns with various markers of intrauterine infection. (17000235)
2006
8
Relationship between cytokine gene polymorphism and susceptibility to hepatitis B virus intrauterine infection]. (15941525)
2005
9
Relationship between cytokines gene polymorphism and susceptibility to hepatitis B virus intrauterine infection. (16232344)
2005
10
The possible role of intrauterine infections in unexplained second trimester abortions and macerated stillbirths: a study from a single center. (15254560)
2004
11
Intrauterine infections. (15490912)
2004
12
Intrauterine infections and birth defects. (15745253)
2004
13
Subacute sclerosing panencephalitis after intrauterine infection. (15384893)
2004
14
Two brothers with findings resembling congenital intrauterine infection-like syndrome (pseudo-TORCH syndrome). (12833411)
2003
15
Usefulness of determination of granulocyte elastase plasma level, c-reactive protein and white blood cell count in prediction in intrauterine infection in pregnant women after PROM]. (14669391)
2003
16
Congenital intrauterine infection like syndrome of microcephaly, intracranial calcification and CNS disease. (12368535)
2002
17
Maternal serum and amniotic fluid cytokines in patients with preterm premature rupture of membranes with and without intrauterine infection. (12445984)
2002
18
Eye manifestations of intrauterine infections. (11705152)
2001
19
Incidence, clinical spectrum, and outcome of intrauterine infections in neonates. (10893916)
2000
20
Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection. (10920315)
2000
21
Amniotic fluid lactoferrin in intrauterine infection. (10195738)
1999
22
Cytokine release from placental endothelial cells, a process associated with preterm labour in the absence of intrauterine infection. (10080881)
1999
23
Interleukin-6 concentrations in cervical secretions in the prediction of intrauterine infection in preterm premature rupture of the membranes. (9701687)
1998
24
Intrauterine infections. I. The role of C-reactive protein, white blood cell count and erythrocyte sedimentation rate in pregnant women in the detection of intrauterine infection after preliminary rupture of membranes]. (9813940)
1998
25
Ultrasonographic assessment of the uterine cervix and interleukin-8 concentrations in cervical secretions predict intrauterine infection in patients with preterm labor and intact membranes. (9744050)
1998
26
The autosomal recessive congenital intrauterine infection-like syndrome of microcephaly, intracranial calcification, and CNS disease: report of another Bedouin family. (9571284)
1998
27
The diagnosis of intrauterine infection in women with preterm premature rupture of the membranes (PPROM). (9917940)
1998
28
Interleukin 8 and granulocyte elastase in the tracheobronchial aspirate of infants without respiratory distress syndrome or intrauterine infection and development of chronic lung disease. (9316287)
1997
29
Stillbirths and intrauterine infection, histologic chorioamnionitis and microbiological findings. (9236308)
1996
30
Low amniotic fluid glucose levels are a specific but not a sensitive marker for subclinical intrauterine infections in patients in preterm labor with intact membranes. (8059814)
1994
31
The TORCH screen and intrauterine infections. (8198407)
1994
32
The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection. (7943101)
1994
33
Placental interleukin-6 production is enhanced in intrauterine infection but not in labor. (8420357)
1993
34
Intrauterine infections and their association with stillbirth and preterm birth in Maputo, Mozambique. (8449441)
1993
35
Human placenta constitutively produces interleukin-8 during pregnancy and enhances its production in intrauterine infection. (1391327)
1992
36
IgA-secreting cells in the blood of premature and term infants: normal development and effect of intrauterine infections. (1809028)
1991
37
Erythromycin therapy for subclinical intrauterine infections in threatened preterm delivery--a preliminary report. (3210111)
1988
38
Influence of intrauterine infections and follicular development on the response to GnRH administration in postpartum dairy cows. (16726440)
1988
39
Evidence for a role of intrauterine infections in the pathogenesis of cystic ovaries in postpartum dairy cows. (16726355)
1987
40
Intrauterine infections. (3836968)
1985
41
Ascending intrauterine infections in rhesus monkeys. (7174462)
1982
42
Eye findings in intrauterine infections. (6273047)
1981
43
Ampicillin and gemtamicin in the treatment of fetal intrauterine infections. (7365666)
1980
44
Intrauterine infections in nonhuman primates. (119050)
1979
45
Intrauterine infection of mice with St. Louis encephalitis virus: immunological, physiological, neurological, and behavioral effects on progeny. (1193727)
1975
46
Intrauterine infections induced by mumps virus in hamsters. (4602053)
1974
47
Pathogenesis of intrauterine infections in rats due to reovirus type 3. I. Virologic studies. (4349899)
1973
48
Intrauterine infections: problems and prevention. (4123409)
1973
49
Intrauterine infections: chairman's summary. (4349343)
1972
50
Intrauterine infections: introduction. (4488019)
1972

Variations for Intrauterine Infections

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Expression for genes affiliated with Intrauterine Infections

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Intrauterine Infections

Search GEO for disease gene expression data for Intrauterine Infections.

Pathways for genes affiliated with Intrauterine Infections

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50PathCards, 30KEGG
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Pathways related to Intrauterine Infections according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5CD209, CLEC4M
29.5CD209, CLEC4M
39.5CD209, CLEC4M

Compounds for genes affiliated with Intrauterine Infections

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45Novoseek, 24HMDB, 11DrugBank
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Compounds related to Intrauterine Infections according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1allergens459.6CD209, CLEC4M
2galactose459.6CLEC4M, CD209
3pseudouridine45 2410.5DKC1, TERC
4rrna459.5DKC1, TERC
5carbohydrates459.5CD209, CLEC4M
6polysaccharide459.5CD209, CLEC4M
7uridine45 24 1111.4DKC1, TERC
8mannose459.4CD209, CLEC4M
9lipid458.3TERC, MMP8, CD209

GO Terms for genes affiliated with Intrauterine Infections

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16Gene Ontology
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Cellular components related to Intrauterine Infections according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.7CD209, MMP8, CLEC4M

Biological processes related to Intrauterine Infections according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1virion attachment to host cellGO:0190629.7CLEC4M, CD209
2peptide antigen transportGO:0469689.7CLEC4M, CD209
3cell-cell recognitionGO:0099889.7CLEC4M, CD209
4modulation by virus of host morphology or physiologyGO:0190489.6CLEC4M, CD209
5viral genome replicationGO:0190799.6CD209, CLEC4M
6intracellular transport of virusGO:0757339.6CD209, CLEC4M
7leukocyte cell-cell adhesionGO:0071599.5CLEC4M, CD209
8intracellular signal transductionGO:0355569.5CD209, CLEC4M
9antigen processing and presentationGO:0198829.4CD209, CLEC4M
10endocytosisGO:0068979.2CLEC4M, CD209

Molecular functions related to Intrauterine Infections according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1virion bindingGO:0467909.5CD209, CLEC4M
2carbohydrate bindingGO:0302469.5CD209, CLEC4M
3mannose bindingGO:0055379.4CD209, CLEC4M
4peptide antigen bindingGO:0426059.2CD209, CLEC4M

Products for genes affiliated with Intrauterine Infections

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Intrauterine Infections

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet