MCID: INT051
MIFTS: 41

Intussusception malady

Gastrointestinal diseases category

Aliases & Classifications for Intussusception

About this section
Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 59SNOMED-CT, 29ICD9CM, 27ICD10
See all sources

Aliases & Descriptions for Intussusception:

Name: Intussusception 10 47 12 65 36
Intussusception of Intestine 10
Invagination of Intestine 10
 
Intussusception Nos 10
Colon 10


Classifications:



External Ids:

Disease Ontology10 DOID:8446
MeSH36 D007443
ICD9CM29 560.0
ICD1027 K56.1

Summaries for Intussusception

About this section
MalaCards based summary: Intussusception, also known as intussusception of intestine, is related to sarcoma and plasmacytoma, and has symptoms including autosomal dominant inheritanceand intussusception. An important gene associated with Intussusception is STK11 (Serine/Threonine Kinase 11). Affiliated tissues include colon, lung and appendix, and related mouse phenotypes are renal/urinary system and cellular.

Related Diseases for Intussusception

About this section

Diseases related to Intussusception via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 394)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoma30.7CD40LG, CD79A
2plasmacytoma30.4CD40LG, CD79A
3typhoid fever30.3CD40LG, CD79A
4cholecystitis30.2CD40LG, CFTR, CRP
5multiple myeloma29.7CD40LG, CD79A, CRP, IL6
6systemic lupus erythematosus29.6CD40LG, CD79A, CRP, IL6
7peutz-jeghers syndrome10.7
8ileocolitis10.7
9meckel's diverticulum10.6
10lipoma10.6
11rectal prolapse10.5
12adenocarcinoma10.5
13intestinal obstruction10.5
14duodenitis10.4
15gastroduodenitis10.4
16adenoma10.4
17melanoma10.4
18pancreatitis10.4
19gastrointestinal stromal tumor10.3
20intestinal atresia10.3
21cold urticaria10.3CRP, IL6
22cryptomicrotia brachydactyly syndrome10.3CRP, IL6
23acinic cell breast carcinoma10.3CRP, IL6
24dural sinus malformation10.3CRP, IL6
25wissler's syndrome10.3CRP, IL6
26clear cell acanthoma10.3CRP, IL6
27acute myocarditis10.3CD40LG, CRP
28catamenial pneumothorax10.3CRP, IL6
29recurrent corneal erosion10.3CD40LG, CRP
30mononeuritis of lower limb10.3CD40LG, CRP
31congenital chloride diarrhea10.3CRP, IL6
32penis sarcoma10.3CD40LG, CRP
33rocky mountain spotted fever10.3CD40LG, CRP
34supraglottis cancer10.3CD40LG, CRP
35intermediate malignant teratoma10.3CRP, IL6
36keratoderma hereditarium mutilans with ichthyosis10.3CD40LG, CRP
37brucella suis brucellosis10.3CRP, IL6
38plantar fasciitis10.3CRP, IL6
39akinetopsia10.3CRP, IL6
40cell type benign neoplasm10.3CRP, IL6
41multicentric osteolysis nephropathy10.3CRP, IL6
42ischemic optic neuropathy10.3CRP, IL6
43cystadenoma10.3
44appendicitis10.3
45inflammatory myofibroblastic tumor10.3
46lipomatosis10.3
47cicatricial lagophthalmos10.3CRP, IL6
48hereditary night blindness10.3CRP, IL6
49focal labyrinthitis10.3CD40LG, CRP
50acute disseminated encephalomyelitis10.2CRP, IL6

Graphical network of the top 20 diseases related to Intussusception:



Diseases related to intussusception

Symptoms for Intussusception

About this section

HPO human phenotypes related to Intussusception:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 intussusception HP:0002576

Drugs & Therapeutics for Intussusception

About this section

Drugs for Intussusception (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Citric AcidnutraceuticalPhase 378477-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
2CitrateNutraceuticalPhase 3784

Interventional clinical trials:

(show all 27)
idNameStatusNCT IDPhase
1RCT: STARR vs BiofeedbackCompletedNCT00556283Phase 4
2Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)CompletedNCT00256984Phase 4
3Stapled Trans Anal Rectal Resection (STARR) for Outlet Obstruction: Functional and Morphological OutcomeCompletedNCT00521872Phase 4
4Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot StudyRecruitingNCT02542462Phase 4
5Rotavirus Efficacy and Safety Trial (REST)(V260-006)CompletedNCT00090233Phase 3
6Long-term Efficacy and Safety of Subjects Approximately 3 Years After Priming With 2 Doses of GSK Bio's HRV Vaccine.CompletedNCT00420316Phase 3
7A Study to Test 2 Doses of GSK Biologicals' Oral Live Attenuated Human Rotavirus (HRV) Vaccine in Healthy InfantsCompletedNCT00197210Phase 3
8A Study of the Immunogenicity, Tolerability, and Safety of a New Formulation of RotaTeq™ in Infants (V260-035)CompletedNCT01600092Phase 3
9A Study to Test 2 Doses of the HRV Vaccine in Healthy Infants.CompletedNCT00140673Phase 3
10Efficacy, Safety, and Immunogenicity of V260 in Healthy Chinese Infants (V260-024)CompletedNCT02062385Phase 3
11Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in NigerRecruitingNCT02145000Phase 3
12A Phase III Clinical Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116EActive, not recruitingNCT01305109Phase 3
13Dose Escalation Study to Evaluate Oral Rotavirus Vaccine 116E Live Attenuated in Healthy Infants 8 to 20 Weeks OldActive, not recruitingNCT00439660Phase 1, Phase 2
14Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel SyndromeCompletedNCT00767364Phase 1
15Intussusception Surveillance After Rotarix Introduction in MexicoCompletedNCT00595205
16Study to Assess the Incidence of Intussusception in Children < 2 Years of Age in SingaporeCompletedNCT01177839
17Study on the Incidence of Intussusception (IS) in Children Aged < 12 Months in JapanCompletedNCT01479491
18Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTMCompletedNCT00673400
19Implementing Hospital-based Active Surveillance Procedures for Vaccine Safety Monitoring at IMSS Hospitals in MexicoCompletedNCT00436358
20Special Drug Use Investigation for ROTARIX®CompletedNCT01636739
21Drug Use Investigation for ROTARIX®CompletedNCT01636193
22Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic PatientsCompletedNCT02239302
23Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile IntussusceptionRecruitingNCT02691858
24Does the Stapled Transanal Rectal Resection (STARR Procedure) Has an Effect on Anal Compliance ?RecruitingNCT02052063
25Surgical Treatment of Obstructed Defecation SyndromeRecruitingNCT01899209
26Evaluation of Universal Rotavirus Vaccination ProgramRecruitingNCT01273077
27Safety Study of GSK Biologicals' Rotavirus Vaccine (Rotarix®) Administered to Children Aged <1 Year in the United StatesActive, not recruitingNCT00875641

Search NIH Clinical Center for Intussusception


Cochrane evidence based reviews: Intussusception

Genetic Tests for Intussusception

About this section

Anatomical Context for Intussusception

About this section

MalaCards organs/tissues related to Intussusception:

33
Colon, Lung, Appendix, Small intestine, Pancreas, B cells, Breast

Animal Models for Intussusception or affiliated genes

About this section

MGI Mouse Phenotypes related to Intussusception:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.1BAG6, CD40LG, CD79A, IL6, STK11
2MP:00053847.1BAG6, CD40LG, CD79A, CFTR, IL6, STK11
3MP:00053766.6BAG6, CD40LG, CD79A, CFTR, CRP, IL6

Publications for Intussusception

About this section

Articles related to Intussusception:

(show top 50)    (show all 790)
idTitleAuthorsYear
1
Rare case of adult jejunojejunal intussusception secondary to angiolipoma. (25883255)
2015
2
Jejunojejunal Intussusception. (25858341)
2015
3
Adenomyoma of the small intestine a rare pathological lead point for intussusception in an infant. (25392787)
2014
4
Jejunojejunal intussusception secondary to submucosal lipoma resulting in a 5-year history of intermittent abdominal pain. (25355752)
2014
5
Colo-colic intussusception secondary to lipomatous polyp in an adult. (23462651)
2013
6
Intussusception with complete twisting of mesenteric root after Roux-en-Y gastric bypass. (23522620)
2013
7
Aortic intussusception complicating diagnostic angiography: recognition and management. (23608257)
2013
8
Perspectives on intussusception. (23597529)
2013
9
Colonic intussusception caused by anisakiasis: a case report and review of the literature. (23318852)
2013
10
Jejunal intussusception and polyps with different types of malignant transformation in Peutz-Jeghers syndrome: Report of a case. (23255928)
2013
11
Intussusception risk and disease prevention associated with rotavirus vaccines in Australia's National Immunization Program. (23964090)
2013
12
Management of intussusception in resource-limited settings. (23994003)
2013
13
Intussusception as a presenting feature of Burkitt lymphoma: implications for management and outcome. (21969235)
2012
14
Ileocolic intussusception due to a cecal endometriosis: case report and review of literature. (22676322)
2012
15
Antibiotics administration before enema reduction of intussusception: is it necessary? (22595575)
2012
16
Appendiceal intussusception to the cecum caused by mucocele of the appendix: Laparoscopic approach. (22706297)
2012
17
Japanese guidelines for the management of intussusception in children, 2011. (22748165)
2012
18
Prevalence of severe acute rotavirus gastroenteritis and intussusceptions in Ghanaian children under 5 years of age. (22337844)
2012
19
Sonographically guided enema for intussusception reduction: a safer alternative to fluoroscopy. (23011611)
2012
20
The role of plain radiography in assessing intussusception with vascular compromise in children. (22291835)
2011
21
Intussusception: incidence and treatment-insights from the nationwide German surveillance. (21415671)
2011
22
Prolapsed sigmoid intussusception per anus in an elderly man: a case report. (21849068)
2011
23
Small bowel intussusception caused by a jejunal polyp in Peutz-Jeghers syndrome: a case treated with double balloon enteroscopy. (20658191)
2011
24
Laparoscopy-assisted hydrostatic in situ reduction of intussusception: A reasonable alternative? (21430840)
2011
25
Heterotopic gastric mucosa: a rare cause of jejunal intussusception. (21944611)
2011
26
Adenomyoma of the ileum leading to intussusception. (22110422)
2011
27
Intestinal spirochetosis as a causative factor for colocolic intussusception. (21274545)
2011
28
Incidence of intussusception in early infancy: a capture-recapture estimate for Germany. (21698555)
2011
29
Severe type of adult jejunal intussusception caused by long intestinal tube in a patient with intestinal obstruction due to cecal carcinoma. (22688937)
2011
30
Intussusception: an anatomical perspective with review of the literature. (21268121)
2011
31
Voluminous intussusception involving the whole midgut in a teenager: a unique differentiation from abdominal cocoon. (21512845)
2011
32
Multiple Small Bowel Intussusceptions Caused by Kaposi's Sarcoma: The Radiologist's Point of View. (21572620)
2011
33
Paediatric intussusception caused by acquired immunodeficiency syndrome-associated Kaposi sarcoma. (20535484)
2010
34
A ganglioneuroma of the sigmoid colon presenting as leading point of intussusception in a child: a case report. (19159704)
2009
35
Contents of serum albumin after surgical operation in children with acute intussusception]. (19374811)
2009
36
HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2. (19403561)
2009
37
Ileo-ileal intussusception due to inverted Meckel's diverticulum. (19803269)
2009
38
Jejunojejunal intussusception by a known jejunal adenocarcinoma. (18815635)
2008
39
Massive mucinous cystadenoma of the appendix with intussusception in an adult: usefulness of reconstructed computed tomography images. (18301985)
2008
40
Intussusception mimicking rectal prolapse. (18327576)
2008
41
Multiple lipomatosis--a rare cause for small bowel intussusception. (18157202)
2007
42
Delta-F508 cystic fibrosis mutation is not linked to intussusception: implications for rotavirus vaccine. (12969205)
2003
43
Laparoscopic reduction of an ileoileal intussusception and resection of an inverted Meckel's diverticulum in an adult. (12728389)
2003
44
Intestinal intussusception and occlusion caused by small bowel polyps in the Peutz-Jeghers syndrome. Management by combined intraoperative enteroscopy and resection through minimal enterostomy: case report. (11313662)
2000
45
Intussusception secondary to Meckel's diverticulum detection with Tc-99m monoclonal antibodies to granulocytes (Leukoscan). (8922842)
1996
46
Intussusception-type antireflux valve in the Roux-en-Y loop to prevent ascending cholangitis after hepatic portojejunostomy. (2313499)
1990
47
Small bowel obstruction by intussusception in a bladder diverticulum: complication of inguinal hernia repair. (3122870)
1987
48
Recurrent acute pancreatitis and intussusception complicating an intraluminal duodenal diverticulum. (6786954)
1981
49
Extramedullary plasmacytoma of the colon: a rare cause of intussusception. (889191)
1977
50
ACCESSORY PANCREAS WITH INTUSSUSCEPTION. (17863874)
1918

Variations for Intussusception

About this section

Expression for genes affiliated with Intussusception

About this section
Search GEO for disease gene expression data for Intussusception.

Pathways for genes affiliated with Intussusception

About this section

GO Terms for genes affiliated with Intussusception

About this section

Cellular components related to Intussusception according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0CD40LG, CD79A, IL6

Biological processes related to Intussusception according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipid storageGO:001088810.2CRP, IL6
2regulation of angiogenesisGO:00457659.7IL6, TEK
3B cell proliferationGO:00421009.6CD40LG, CD79A
4negative regulation of apoptotic processGO:00430668.3BAG6, CD40LG, IL6, TEK

Sources for Intussusception

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet