Aliases & Classifications for Iridocyclitis

Summaries for Iridocyclitis

MalaCards based summary : Iridocyclitis, also known as primary iridocyclitis, is related to fuchs' heterochromic uveitis and juvenile rheumatoid arthritis. An important gene associated with Iridocyclitis is DEK (DEK Proto-Oncogene), and among its related pathways/superpathways are NF-kappaB Signaling and Influenza A. The drugs Methotrexate and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial.

Wikipedia : 72 Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the... more...

Related Diseases for Iridocyclitis

Diseases related to Iridocyclitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 fuchs' heterochromic uveitis 33.0 CYP11B1 MRAP TNFAIP3
2 juvenile rheumatoid arthritis 30.1 DEK HLA-DPB1
3 hypopyon 30.0 HLA-B MRAP
4 chorioretinitis 29.9 CD40LG MRAP
5 glaucomatocyclitic crisis 29.6 HLA-B MRAP
6 spondylitis 29.3 CD40LG HLA-B
7 iritis 29.3 CD40LG HLA-B MRAP
8 spondyloarthropathy 1 29.0 CD40LG HLA-B MRAP
9 rubella 29.0 CD40LG HLA-B HLA-DPB1
10 lens-induced iridocyclitis 12.1
11 gonococcal iridocyclitis 11.9
12 infectious anterior uveitis 11.5
13 phacoanaphylactic uveitis 11.4
14 anterior uveitis 11.3
15 retinal vasculitis 11.0
16 uveitis 10.6
17 arthritis 10.4
18 idiopathic anterior uveitis 10.3
19 rheumatoid arthritis 10.3
20 cataract 10.2
21 optic papillitis 10.2 CD40LG MRAP
22 acute retinal necrosis syndrome 10.2 CD40LG MRAP
23 diffuse infiltrative lymphocytosis syndrome 10.2 MRAP TNFRSF10B
24 urethritis 10.2 CD40LG MRAP
25 cervix disease 10.2 CD40LG MRAP
26 transient arthritis 10.2 CD40LG MRAP
27 vulvitis 10.2 CD40LG MRAP
28 acute salpingitis 10.2 CD40LG MRAP
29 urethral syndrome 10.2 CD40LG MRAP
30 coccidiosis 10.2 CD40LG MRAP
31 palindromic rheumatism 10.2 MRAP TNFRSF10B
32 conjunctival disease 10.2 CD40LG MRAP
33 marginal zone b-cell lymphoma 10.2 CD40LG TNFAIP3
34 hypersensitivity reaction type iv disease 10.1 CD40LG MRAP
35 la crosse encephalitis 10.1 CD40LG TNFRSF10B
36 keratitis, hereditary 10.1
37 lymphoma, mucosa-associated lymphoid type 10.1 CD40LG TNFAIP3
38 bone inflammation disease 10.1 CD40LG MRAP
39 herpes simplex 10.0
40 spondyloarthropathy 10.0 HLA-B MRAP
41 geographic tongue 10.0 HLA-B TNFRSF10B
42 vogt-koyanagi-harada disease 10.0
43 infectious posterior uveitis 10.0
44 idiopathic posterior uveitis 10.0
45 retinitis 10.0
46 indeterminate leprosy 10.0 CD40LG HLA-B
47 leprosy 3 9.9
48 echinococcosis 9.9 CD40LG HLA-B
49 chikungunya 9.9
50 toxoplasmosis 9.9

Graphical network of the top 20 diseases related to Iridocyclitis:



Diseases related to Iridocyclitis

Symptoms & Phenotypes for Iridocyclitis

Drugs & Therapeutics for Iridocyclitis

Drugs for Iridocyclitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 92)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
2
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
3
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
4
Certolizumab pegol Approved Phase 4 428863-50-7
5
leucovorin Approved, Nutraceutical Phase 4 58-05-9 143 6006
6
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
7 Folic Acid Antagonists Phase 4
8 Ganciclovir triphosphate Phase 4
9 Nucleic Acid Synthesis Inhibitors Phase 4
10 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
11 Dermatologic Agents Phase 4,Phase 3
12 Vitamin B Complex Phase 4
13 Hormones Phase 4,Phase 3,Phase 2,Phase 1
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
15 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2
16 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
17 Antimetabolites Phase 4
18 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Antimetabolites, Antineoplastic Phase 4
20 Antirheumatic Agents Phase 4,Phase 3
21 Antiviral Agents Phase 4,Phase 3,Phase 1,Phase 2
22 beta-endorphin Phase 4
23 Adrenocorticotropic Hormone Phase 4
24 Tetrahydrozoline Phase 4,Phase 3,Phase 2,Phase 1
25 Ophthalmic Solutions Phase 4,Phase 3,Phase 2,Phase 1
26 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
27 Melanocyte-Stimulating Hormones Phase 4
28 Folate Nutraceutical Phase 4
29 Vitamin B9 Nutraceutical Phase 4
30
Prednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1 50-24-8 5755
31
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1 83-43-2 6741
32
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
33
Ephedrine Approved Phase 3,Phase 1,Phase 2 299-42-3 9294
34
Triamcinolone Approved, Vet_approved Phase 3,Phase 2 124-94-7 31307
35
Pseudoephedrine Approved Phase 3,Phase 1,Phase 2 90-82-4 7028
36
Difluprednate Approved Phase 3,Phase 2 23674-86-4 443936
37
Citric Acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
38 Acyclovir Phase 3
39 Prednisolone acetate Phase 3,Phase 2,Phase 1
40 glucocorticoids Phase 3,Phase 2,Phase 1
41 Methylprednisolone acetate Phase 3,Phase 2,Phase 1
42 Methylprednisolone Hemisuccinate Phase 3,Phase 2,Phase 1
43 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
44 Neuroprotective Agents Phase 3,Phase 2,Phase 1
45 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
46 Antiemetics Phase 3,Phase 2,Phase 1
47 Prednisolone hemisuccinate Phase 3,Phase 2,Phase 1
48 Prednisolone phosphate Phase 3,Phase 2,Phase 1
49 Protective Agents Phase 3,Phase 2,Phase 1
50 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 54)

# Name Status NCT ID Phase Drugs
1 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
2 A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach Versus Routine Treatment Completed NCT02897115 Phase 4
3 Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis Recruiting NCT02943057 Phase 4 2% guttae ganciclovir
4 Open Label Study of Acthar SQ Gel Injection in Patients With Active Anterior Uveitis Recruiting NCT02769702 Phase 4 Acthar
5 A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU Active, not recruiting NCT03020992 Phase 4 Certolizumab Pegol
6 Methotrexate in the Treatment of Axial Spondyloarthritis Withdrawn NCT00298012 Phase 4 Methotrexate
7 Herpetic Eye Disease Study (HEDS) I Unknown status NCT00000138 Phase 3 Prednisolone Phosphate;Acyclovir
8 Safety and Efficacy of Difluprednate 0.05% for the Treatment of Anterior Uveitis Completed NCT01201798 Phase 3 Difluprednate 0.05% ophthalmic emulsion;Prednisolone acetate 1.0% ophthalmic suspension
9 A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis Completed NCT00404885 Phase 3 Placebo;LX211;LX211;LX211
10 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis Completed NCT00406887 Phase 3 Difluprednate Ophthalmic Emulsion
11 Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis Completed NCT01505088 Phase 3 40 mg/mL Dexamethasone phosphate ophthalmic solution;Prednisolone Acetate (1%) Eyedrops;100 mM sodium citrate buffer solution;Placebo Eyedrops
12 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis Completed NCT00407056 Phase 3 Difluprednate Ophthalmic Emulsion
13 Herpetic Eye Disease Study (HEDS) II Completed NCT00000139 Phase 3 Acyclovir
14 Study of Difluprednate in the Treatment of Uveitis Completed NCT00501579 Phase 3 Difluprednate;Prednisolone Acetate
15 A Phase 3 Study to Evaluate ADX-102 Ophthalmic Solution in Subjects With Non-infectious Anterior-uveitis. Recruiting NCT03131154 Phase 3 ADX-102 Ophthalmic Solution (0.5%);Vehicle of ADX-102 Ophthalmic Solution
16 Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis Recruiting NCT02517619 Phase 3 Dexamethasone Phosphate Ophthalmic Solution;Prednisolone Acetate Ophthalmic (1%)
17 A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis Recruiting NCT03129100 Phase 3 Ixekizumab;Placebo
18 A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis Recruiting NCT02757352 Phase 3 Ixekizumab;Placebo
19 A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis Recruiting NCT02696798 Phase 3 Ixekizumab;Placebo
20 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis Active, not recruiting NCT01148225 Phase 3 adalimumab
21 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Active, not recruiting NCT03097315 Phase 3
22 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Active, not recruiting NCT02595398 Phase 3 4mg CLS-TA Suprachoriodal Injection;Sham Procedure
23 A Study of Ixekizumab (LY2439821) in bDMARD-Naive Participants With Radiographic Axial Spondyloarthritis Active, not recruiting NCT02696785 Phase 3 Ixekizumab;Placebo;Adalimumab
24 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Anterior Uveitis Terminated NCT00333996 Phase 2, Phase 3 Dexamethasone
25 Proof of Concept Study to Evaluate Safety and Efficacy of LME636 in the Treatment of Acute Anterior Uveitis Completed NCT02482129 Phase 2 LME636 60 mg/mL ophthalmic solution;Dexamethasone 0.1% ophthalmic solution;LME636 Vehicle
26 A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis Completed NCT02406209 Phase 2 NS2;Prednisolone acetate ophthalmic suspension (1%)
27 Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis Completed NCT02309385 Phase 1, Phase 2 8% Dexamethasone Sodium Phosphate - Visulex;15% Dexamethasone Sodium Phosphate - Visulex;Prednisolone Acetate (1%) Eye Drops
28 Exploratory Study on Topical ESBA105 in Acute Anterior Uveitis Completed NCT00823173 Phase 2
29 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis Completed NCT00405496 Phase 2 Difluprednate Ophthalmic Emulsion
30 Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis Completed NCT00130637 Phase 2 Daclizumab
31 Topical Interferon Gamma for Macular Edema Secondary to Uveitis Completed NCT01376362 Phase 1, Phase 2 Interferon Gamma-1b
32 Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Anterior Uveitis Completed NCT00694135 Phase 2 EGP-437 1.6 mA-min at 0.4 with EyeGate® II System;EGP-437 4.8 mA-min at 1.2 mA with EyeGate® II System;EGP-437 10.0 mA-min at 2.5 mA with EyeGate® II System;EGP-437 14.0 mA-min at 3.5 mA with EyeGate® II System
33 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2 4 mg CLS-TA;0.8 mg CLS-TA
34 A Phase I/IIa Study for the Treatment of Uveitis With Iontophoresis Withdrawn NCT00499551 Phase 1, Phase 2
35 Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti Completed NCT00876434 Phase 1 Sirolimus
36 Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions Withdrawn NCT02042027 Phase 1 Gamunex-C
37 Acute Anterior Uveitis: Psychic Burden and Pain Unknown status NCT01156285
38 Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis Unknown status NCT01486693
39 Quality of Life and Visual Function in Uveitis Patients Unknown status NCT00407316 Early Phase 1
40 Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's Disease Unknown status NCT00931957 Etanercept, Methotrexate, Prednisolone
41 PEMF: an Adjunct Therapy for Anterior Uveitis Completed NCT01154010
42 Topical Administration of 0.15% Ganciclovir Gel for CMV Anterior Uveitis / Endotheliitis Completed NCT01647529 Ganciclovir
43 Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications Completed NCT00476593 Diclofenac;Dexamethasone
44 Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis Completed NCT00404482 Cyclosporine A
45 Aqueous Humor Dynamics and Hypertensive Uveitis Completed NCT02765308
46 Evaluation and Treatment of Patients With Inflammatory Eye Diseases Completed NCT00006188
47 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Anti-toxoplasmosis treatment;Anti-inflammatory treatments
48 Intraocular Pressure (IOP) Assessed by Dynamic Contour Tonometer (DCT) and Goldman Applanation Tonometry (GAT) Completed NCT00552019
49 Diagnostic Criteria in the Diagnosis of Spinal Spondyloarthropathies in Patients With Chronic Low Back Pain (Study P05320)(COMPLETED) Completed NCT00726765
50 Ocular Sarcoidosis Open Label Trial of ACTHAR Gel Recruiting NCT02725177 Repository Corticotropin Injection;Repository Corticotropin Injection -Treatment Extension

Search NIH Clinical Center for Iridocyclitis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Iridocyclitis

Anatomical Context for Iridocyclitis

MalaCards organs/tissues related to Iridocyclitis:

38
Eye, Retina, Endothelial, Neutrophil, Testes, Thyroid, Liver

Publications for Iridocyclitis

Articles related to Iridocyclitis:

(show top 50) (show all 279)
# Title Authors Year
1
Niemann-Pick Disease Type C Associated with Fuchs Heterochromic Iridocyclitis. ( 29387679 )
2017
2
Anti-dense Fine Speckled 70 Autoantibodies in Japanese Children with Dermatomyositis, Localized Scleroderma, and Idiopathic Arthritis with Iridocyclitis. ( 28461535 )
2017
3
Intraocular Lymphoma Masquerading as Recurrent Iridocyclitis: Findings Based on in vivo Confocal Microscopy. ( 29099641 )
2017
4
The unusual association of inverse retinitis pigmentosa and Fuchs' heterochromic iridocyclitis. ( 28127443 )
2017
5
Leprosy Presenting with Iridocyclitis: A Diagnostic Dilemma. ( 29090057 )
2017
6
Phacoemulsification Versus Manual Small Incision Cataract Surgery in Patients With Fuchs Heterochromic Iridocyclitis. ( 26939115 )
2016
7
Recurrent iridocyclitis due to cotton fiber in anterior chamber. ( 28242892 )
2016
8
Risk Factors for Glaucoma in a Cohort of Patients with Fuchs Heterochromic Iridocyclitis. ( 27494676 )
2016
9
Fuchs' Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis. ( 27781126 )
2016
10
Zika virus-related hypertensive iridocyclitis. ( 26840174 )
2016
11
Syphilis iridocyclitis in a patient with type 1 diabetes. ( 27180731 )
2015
12
Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome. ( 25861394 )
2015
13
Fuch's Heterochromic Iridocyclitis in Iran: Is the Disease Going to Fade Away? ( 26730326 )
2015
14
Polymorphisms in cytomegalovirus genotype in immunocompetent patients with corneal endotheliitis or iridocyclitis. ( 25963863 )
2015
15
Analysis on the psychological characteristics of patients with acute iridocyclitis. ( 26086022 )
2015
16
Bilateral acute iris transillumination (BAIT) initially misdiagnosed as acute iridocyclitis. ( 25945534 )
2015
17
Small-incision cataract surgery in patients with Fuch's heterochromic iridocyclitis. ( 25680261 )
2014
18
Herniation of the retina in the central macula in an adult after iridocyclitis. ( 26011975 )
2014
19
Clinical, histopathological and immunohistochemical characterization of a novel equine ocular disorder: heterochromic iridocyclitis with secondary keratitis in adult horses. ( 25399915 )
2014
20
Implantation of iris-claw Artisan intraocular lens for aphakia in Fuchs' heterochromic iridocyclitis. ( 23571252 )
2013
21
Polymorphisms of TNFAIP3 Gene in a Chinese Han Population with Fuchs Heterochromic Iridocyclitis. ( 23463983 )
2013
22
Associations of Fuchs heterochromic iridocyclitis in a South Indian patient population. ( 23514352 )
2013
23
Hypertensive iridocyclitis associated with delayed onset biopsy proven Cytomegalovirus retinitis. ( 23548320 )
2013
24
Surgical management of secondary glaucoma in Fuchs' heterochromic iridocyclitis. ( 23519886 )
2013
25
Frequency of iridocyclitis in patients with early psoriatic arthritis: a prospective, follow up study. ( 22898222 )
2012
26
Chikungunya virus iridocyclitis in Fuchs' heterochromic iridocyclitis. ( 22218256 )
2012
27
Adenoma of the nonpigmented ciliary epithelium presenting with recurrent iridocyclitis: unique expression of glial fibrillary acidic protein. ( 21088853 )
2011
28
Fuchs heterochromic iridocyclitis and the rubella virus. ( 21897135 )
2011
29
Bilateral acute depigmentation of the iris first misdiagnosed as acute iridocyclitis. ( 21633847 )
2011
30
Fuchs' heterochromic iridocyclitis associated with ocular toxocariasis. ( 21331701 )
2011
31
Corneal astigmatism in unilateral Fuchs heterochromic iridocyclitis. ( 21595529 )
2011
32
Sarcoidosis presenting with massive splenomegaly in a child with a history of iridocyclitis and sensorineural deafness. ( 20615071 )
2010
33
Confocal scan features of keratic precipitates in Fuchs heterochromic iridocyclitis. ( 19907293 )
2010
34
The possible role of systemic azithromycin for idiopathic iridocyclitis. ( 19891670 )
2010
35
Levocetirizine-induced iridocyclitis in a patient with allergic rhinitis. ( 20232781 )
2010
36
Chikungunya virus iridocyclitis in Fuchs' heterochromic iridocyclitis. ( 20952847 )
2010
37
Expression Profile of Intravitreous Cytokines, Chemokines and Growth Factors in Patients with Fuchs Heterochromic Iridocyclitis. ( 20737053 )
2010
38
Rubella virus as a possible etiological agent of Fuchs heterochromic iridocyclitis. ( 20585798 )
2010
39
Klebsiella pneumoniae endophthalmitis secondary to liver abscess presenting as acute iridocyclitis. ( 19772282 )
2009
40
Presumed Fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: comparison of cytomegalovirus-positive and -negative eyes. ( 19463548 )
2009
41
Retinal thickening in iridocyclitis. ( 19477710 )
2009
42
Fuchs heterochromic iridocyclitis--syndrome, disease, or both? ( 19782794 )
2009
43
Idiopathic no more: clues to the pathogenesis of Fuchs heterochromic iridocyclitis and glaucomatocyclitic crisis. ( 18435976 )
2008
44
Presumed fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: comparison of cytomegalovirus-positive and negative eyes. ( 19027423 )
2008
45
Kinetics of aqueous flare, intraocular pressure and virus-DNA copies in a patient with cytomegalovirus iridocyclitis without retinitis. ( 17522780 )
2007
46
Epidemiologic relationship between fuchs heterochromic iridocyclitis and the United States rubella vaccination program. ( 17631266 )
2007
47
Iridocyclitis associated with angle-supported phakic intraocular lenses. ( 16814060 )
2006
48
Ophthalmomyiasis associated with Fuchs heterochromic iridocyclitis. ( 17031305 )
2006
49
When should intraocular lenses be implanted in patients with juvenile idiopathic arthritis-associated iridocyclitis? ( 17057416 )
2006
50
Hypertensive iridocyclitis. ( 16782945 )
2006

Variations for Iridocyclitis

Expression for Iridocyclitis

Search GEO for disease gene expression data for Iridocyclitis.

Pathways for Iridocyclitis

Pathways related to Iridocyclitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.06 CD40LG TNFAIP3 TNFRSF10B
2
Show member pathways
11.95 HLA-B HLA-DPB1 TNFAIP3 TNFRSF10B
3 11.74 HLA-B HLA-DPB1 TNFAIP3
4 11.6 CD40LG TNFAIP3 TNFRSF10B
5 10.96 CD40LG HLA-B HLA-DPB1
6 10.8 CD40LG TNFAIP3

GO Terms for Iridocyclitis

Cellular components related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ER to Golgi transport vesicle membrane GO:0012507 9.16 HLA-B HLA-DPB1
2 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.96 HLA-B HLA-DPB1
3 cell surface GO:0009986 8.92 CD40LG HLA-B HLA-DPB1 TNFRSF10B

Biological processes related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.58 CD40LG TNFAIP3 TNFRSF10B
2 T cell costimulation GO:0031295 9.37 CD40LG HLA-DPB1
3 interferon-gamma-mediated signaling pathway GO:0060333 9.32 HLA-B HLA-DPB1
4 positive regulation of T cell proliferation GO:0042102 9.26 CD40LG HLA-DPB1
5 antigen processing and presentation GO:0019882 9.16 HLA-B HLA-DPB1
6 immune response GO:0006955 9.02 CD40LG CYP11B1 HLA-B HLA-DPB1 TNFRSF10B
7 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 8.96 TNFAIP3 TNFRSF10B

Molecular functions related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.62 HLA-B HLA-DPB1

Sources for Iridocyclitis

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