MCID: IRT001
MIFTS: 39

Iritis malady

Summaries for Iritis

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Uveitis is, broadly, inflammation of the uvea. The uvea consists of the middle, pigmented vascular... more...

MalaCards: Iritis is related to arthritis and ankylosing spondylitis. An important gene associated with Iritis is PRND (prion protein 2 (dublet)), and among its related pathways are Primary immunodeficiency and Immune response Fc epsilon RI pathway. The drugs tropicamide and loteprednol etabonate and the compounds okt3 and sulfolipid i have been mentioned in the context of this disorder. Affiliated tissues include skin, retina and b cells.

Aliases & Classifications for Iritis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH
See all sources

Aliases & Descriptions:

iritis 8 10 61


External Ids:

Disease Ontology8 DOID:1406
NCIt40 C50621
SNOMED-CT57 65074000
MeSH35 D007500

Related Diseases for Iritis

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Iritis:



Diseases related to iritis

Clinical Features for Iritis

Drugs & Therapeutics for Iritis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Iritis

Drug clinical trials:

Search ClinicalTrials for Iritis

Search NIH Clinical Center for Iritis

Search CenterWatch for Iritis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Iritis

Anatomical Context for Iritis

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Iritis:

33
Skin, Retina, B cells, Endothelial

Animal Models for Iritis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Iritis

Sources:
51PubMed
See all sources

Articles related to Iritis:

(show top 50)    (show all 223)
idTitleAuthorsYear
1
Visante OCT in the diagnosis of caterpillar-induced iritis. (23931492)
2013
2
Lay Person Slit Lamp Detection of Iritis in Absence of an Eye MD: Test of a Portable Model of Cells and Flare. (22747766)
2012
3
Iritis and iris atrophy after eyebrow epilation with alexandrite laser. (22205833)
2011
4
Iritis, ptosis, and sequential severe loss of vision in a patient with essential thrombocytosis. (19696799)
2010
5
Bilateral ankle edema with bilateral iritis. (16633708)
2007
6
Placement of a collagen glaucoma drainage device to control intraocular pressure and chronic iritis secondary to juvenile rheumatoid arthritis. (12027105)
2002
7
Pouchitis-associated iritis (uveitis) following total proctocolectomy and ileal pouch-to-anal anastomosis in ulcerative colitis. (11240384)
2001
8
Iritis associated with Sweet's syndrome. (10971503)
2000
9
Iritis associated with intravenous cidofovir. (10084411)
1999
10
Expression of stress-response protein 60 in iritis associated with experimental autoimmune encephalomyelitis. (10672873)
1999
11
Low-dose methotrexate in the treatment of severe juvenile rheumatoid arthritis and sarcoid iritis. (10358815)
1999
12
Cytomegalovirus iritis. (9824866)
1998
13
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis. (9194724)
1997
14
Sulfonamide-induced iritis. (8857810)
1996
15
Iritis. How to recognize and manage a potentially sight-threatening disease. (8632971)
1996
16
Arthritis and iritis after bacillus Calmette-GuAcrin therapy. (8992017)
1995
17
Metipranolol-associated granulomatous iritis. (7977597)
1994
18
Ovine iritis. (8498008)
1993
19
Iritis and papillitis as a primary presentation of Lyme disease. (2310116)
1990
20
Conjunctivitis versus iritis. (2400624)
1990
21
Iritis in children with varicella. (2391625)
1990
22
Bovine iritis. (2756627)
1989
23
Acute iritis. How to preserve good vision. (2780436)
1989
24
Is there a link between iritis and diabetic autonomic neuropathy? (3083944)
1986
25
Diabetic autonomic neuropathy and iritis: an association suggesting an immunological cause. (6432089)
1984
26
Association of foveomacular retinitis, ankylosing spondylitis, iritis, and acquired iris atrophy. (556150)
1979
27
EOG during iritis. (999622)
1976
28
Early acute aseptic iritis after cataract extraction. (1084068)
1976
29
Recurrent iritis. (1131606)
1975
30
Iridectomy for the treatment of acute iritis, (Preliminary report). (4466556)
1974
31
Leprotic iritis and blindness. (4677492)
1972
32
Pathology of Herpes Simplex Kerato-Iritis. (16693633)
1963
33
A case of gouty iritis. (13915558)
1962
34
The management of iritis from the standpoint of the general practitioner. (13243972)
1955
35
Iritis and glaucoma associated with mumps. (13147625)
1954
36
Cortisone in iritis. (14897439)
1951
37
Cortisone in the treatment of recurrent iritis associated with Marie-Struempell spondylitis. (15414830)
1950
38
Subconjunctival injection of cortisone in iritis. (14778735)
1950
39
Rheumatoid iritis. (18905681)
1948
40
Acute iritis, including acute iridocyclitis and acute uveitis. (20294764)
1947
41
Recurrent aphthous ulceration of oral mucous membrane and genitals associated with recurrent hypopyon iritis (Behcet's syndrome). (20994217)
1946
42
The role of lens substance in experimental gonorrheal iritis. (21000616)
1946
43
Iritis in the Rheumatic Affections. (20786657)
1946
44
Syphilitic iritis with particular reference to the Herxheimer reaction as a diagnostic aid and response to different treatment including penicillin. (21006582)
1945
45
Ophthalmology: Iritis. (18740596)
1928
46
The Treatment of a Case of Cyclo-Iritis Following Senile Cataract Extraction. (20316669)
1928
47
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979873)
1917
48
DISCUSSION ON THE A8TIOLOGY AND TREATMENT OF IRITIS. (20904264)
1917
49
Case of Venereal Iritis, with Observations. (20793685)
1845
50
On Iritis in Infancy. (20793706)
1845

Genetic Variations for Iritis

Expression for genes affiliated with Iritis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Iritis

Search GEO for disease gene expression data for Iritis.

Pathways for genes affiliated with Iritis

Sources:
30KEGG, 12EMD Millipore
See all sources

Compounds for genes affiliated with Iritis

Sources:
45Novoseek, 11DrugBank, 24HMDB, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience
See all sources

Compounds related to Iritis according to GeneCards/GeneDecks:

(show all 36)
idCompoundScoreTop Affiliating Genes
1okt34510.2CD40LG
2sulfolipid i459.7CD79A, CD40LG
3sandoglobulin459.7CD79A, CD40LG
4vancomycin45 1110.7CD79A, CD40LG
5blys459.7CD79A, CD40LG
6tuberculin459.7CD40LG, CD79A
7praziquantel45 1110.7CD40LG, CD79A
8hemocyanin459.7CD79A, CD40LG
9gliadin459.6CD79A, CD40LG
10pmma459.6CD79A, CD40LG
11silicone459.6CD40LG, CD79A
12mannan459.6CD79A, CD40LG
13ursodeoxycholic acid45 11 2411.5HLA-B, CD40LG
14glutaraldehyde459.5CD79A, CD40LG
15sulfasalazine45 29 50 1112.5CD40LG, CD79A
16valproate459.4CD79A, CD40LG
17cytidine45 11 2411.3CD40LG, CD79A
18anti-fungal459.3CD79A, CD40LG
19pneumococcal459.2CD79A, CD40LG, HLA-B
20phenytoin45 50 29 1112.2HLA-B, CD40LG, CD79A
21polysaccharide459.0CD79A, CD40LG, HLA-B
22cimetidine45 29 1111.0HLA-B, EPO
23ribavirin45 50 1111.0EPO, CD40LG, HLA-B
24fibrinogen459.0CD79A, CD40LG, HLA-B
25mycophenolate mofetil45 50 1110.9CD40LG, CD79A, EPO
26doxycycline45 119.9CD40LG, CD79A, EPO
27vitamin b12458.9EPO, CD79A, CD40LG
28theophylline45 29 11 2411.9CD40LG, CD79A, EPO
29folate458.8EPO, CD79A, CD40LG
30pge2458.8HLA-B, CD40LG, CD79A, PLA2G2D
31ascorbic acid45 249.8EPO, CD79A, CD40LG
32paraffin458.5CD79A, CD40LG, HLA-B
33cyclosporin a45 29 6010.4EPO, CD79A, CD40LG, HLA-B
34lactate458.4HLA-B, CD40LG, CD79A, EPO
35creatinine458.3HLA-B, CD40LG, CD79A, EPO
36testosterone45 60 11 2411.3HLA-B, CD40LG, CD79A, EPO

GO Terms for genes affiliated with Iritis

Sources:
16Gene Ontology
See all sources

Cellular components related to Iritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058867.6SRP72, CD79A, CD40LG, PRND, HLA-B, MRAP

Biological processes related to Iritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:0301839.3CD79A, CD40LG
2B cell proliferationGO:0421009.0CD79A, CD40LG

Products for genes affiliated with Iritis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Iritis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet