MCID: IRT001
MIFTS: 41

Iritis malady

Summaries for Iritis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Uveitis is, broadly, inflammation of the uvea. The uvea consists of the middle, pigmented vascular... more...

MalaCards: Iritis is related to arthritis and ankylosing spondylitis. An important gene associated with Iritis is PRND (prion protein 2 (dublet)), and among its related pathways are Primary immunodeficiency and Immune response Fc epsilon RI pathway. The drugs tropicamide and loteprednol etabonate and the compounds okt3 and sulfolipid i have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and skin.

Aliases & Classifications for Iritis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH
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Aliases & Descriptions:

iritis 8 10 60


External Ids:

Disease Ontology8 DOID:1406
NCIt39 C50621
SNOMED-CT56 65074000
MeSH34 D007500

Related Diseases for Iritis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Iritis:



Diseases related to iritis

Clinical Features for Iritis

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Drugs & Therapeutics for Iritis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Iritis

Drug clinical trials:

Search ClinicalTrials for Iritis

Search NIH Clinical Center for Iritis

Search CenterWatch for Iritis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Iritis

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Anatomical Context for Iritis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Iritis:

32
Eye, Testes, Skin, Retina, Endothelial

Animal Models for Iritis or affiliated genes

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Publications for Iritis

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Sources:
50PubMed
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Articles related to Iritis:

(show top 50)    (show all 223)
idTitleAuthorsYear
1
Intense pulsed light therapy (IPL) induced iritis following treatment for a medial canthal capillary malformation. (24417640)
2014
2
Restrictive (Mechanical) Strabismus: An Epidemic? DNA or Not, Twins Faces, Texas, DRS, Iritis Monitoring. (22747761)
2012
3
Novel molecular imaging approach for subclinical detection of iritis and evaluation of therapeutic success. (20581051)
2010
4
Recurrent iritis after implantation of an iris-fixated phakic intraocular lens for the correction of myopia Case report and clinicopathologic correlation. (16863980)
2006
5
Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis. (15327114)
2004
6
The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis. (12966615)
2003
7
Intravenous cidofovir-induced iritis. (10028099)
1999
8
Cataract surgery in a patient with severe chronic iritis and corneal endothelial damage. (9682104)
1998
9
Blau syndrome of granulomatous arthritis, iritis, and skin rash: a new family and review of the literature. (9508240)
1998
10
Ovine iritis. (8451810)
1993
11
Fibrinous iritis and IOLs. (8479694)
1993
12
Fibrinous iritis due to oxybuprocaine. (2920158)
1989
13
Bovine iritis. (2505428)
1989
14
Bovine iritis. (2750058)
1989
15
A simple test to diagnose iritis. (3676686)
1987
16
Familial granulomatous arthritis, iritis, and rash. (4056967)
1985
17
Acute interstitial nephritis and iritis. Renal-ocular syndrome. (6741981)
1984
18
Aetiopathogenesis of lepromatous iritis. (6544274)
1983
19
Fluorescein iris angiography in nodular sarcoid iritis. (7228508)
1981
20
Pain elicited by consensual pupillary reflex: a diagnostic test for acute iritis. (6118670)
1981
21
Rheumatism and the eyes: iritis as the sole manifestation of ankylosing spondylitis. (637480)
1978
22
Adenine arabinoside therapy in corneal stromal disease and iritis due to herpes simplex. (4359979)
1974
23
Trifluorothymidine treatment of herpetic iritis in rabbits and ocular penetration. (4742994)
1973
24
The chemotherapy of herpes iritis with adenine arabinoside and cytarabine. (4992187)
1970
25
William Hickling Prescott, 1796-1859. An early report of iritis with arthritis. (5331947)
1966
26
HETEROCHROMIC IRITIS AND SECONDARY NEOVASCULAR GLAUCOMA. (14129264)
1964
27
Rheumatic iritis and iridocyclitis. (13650458)
1959
28
Spondylarthritis ankylopoetica associated with iritis. (14413494)
1959
29
Iritis of allergic origin. (13311586)
1956
30
Iritis in ankylosing spondylitis. (13284935)
1955
31
Endophthalmitis phaco-anaphylactia with granulomatous iritis; clinico-pathologic case report. (13092203)
1953
32
Seasonal allergic iritis; case report. (12986591)
1952
33
Iritis associating with spondylitis ankylopoietica. (14831168)
1951
34
Genorrheal iritis: experimental production in the rabbit. (20260324)
1947
35
Iritis in Bechterew-Struempell-Pierre Marie disease. (20341576)
1947
36
Pathology of the Lens in Non-Traumatic Iritis. (16693319)
1943
37
Some Observations on the Results of Densensitization in Tuberculous Iritis. (16693276)
1942
38
Acute Iritis: Its Treatment. (18744207)
1937
39
Osteitis Deformans with Central Senile Exudative Retinitis. Iritis. (19986793)
1929
40
The Character of Iritis Caused by Focal Infection. (16692569)
1921
41
The Radical Cure of GonorrhA9al Iritis. (20905707)
1920
42
The Radical Cure of Gonorrhoeal Iritis. (19981310)
1920
43
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979874)
1917
44
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979870)
1917
45
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979867)
1917
46
Double Tubercular Iritis. (19978219)
1914
47
An Address ON THE EVOLUTION OF TOXAEMIC IRITIS: Delivered at the Oxford Ophthalmological Congress, July, 1914. (20767306)
1914
48
Symmetrical enlargement of parotid and lachrymal glands - nodular iritis. (16692039)
1904
49
Remarks on Gonorrhoeal Iritis. (20755882)
1895
50
Clinical Notes on Iritis: Especially as to the Relative Frequency of Syphilis and Rheumatism, etc., as Causes of the Disease: From an Analysis of Seventy Cases. (20748353)
1876

Genetic Variations for Iritis

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Expression for genes affiliated with Iritis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Iritis

Search GEO for disease gene expression data for Iritis.

Pathways for genes affiliated with Iritis

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29KEGG, 12EMD Millipore
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Compounds for genes affiliated with Iritis

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience
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Compounds related to Iritis according to GeneCards/GeneDecks:

(show all 36)
idCompoundScoreTop Affiliating Genes
1okt34410.2CD40LG
2sulfolipid i449.7CD79A, CD40LG
3sandoglobulin449.7CD79A, CD40LG
4vancomycin44 1110.7CD79A, CD40LG
5blys449.7CD79A, CD40LG
6tuberculin449.7CD40LG, CD79A
7praziquantel44 1110.7CD40LG, CD79A
8hemocyanin449.7CD79A, CD40LG
9gliadin449.6CD79A, CD40LG
10pmma449.6CD79A, CD40LG
11silicone449.6CD40LG, CD79A
12mannan449.6CD79A, CD40LG
13ursodeoxycholic acid44 11 2411.5HLA-B, CD40LG
14glutaraldehyde449.5CD79A, CD40LG
15sulfasalazine44 28 49 1112.5CD40LG, CD79A
16valproate449.4CD79A, CD40LG
17cytidine44 11 2411.3CD40LG, CD79A
18anti-fungal449.3CD79A, CD40LG
19pneumococcal449.2CD79A, CD40LG, HLA-B
20phenytoin44 49 28 1112.2HLA-B, CD40LG, CD79A
21polysaccharide449.0CD79A, CD40LG, HLA-B
22cimetidine44 28 1111.0HLA-B, EPO
23ribavirin44 49 1111.0EPO, CD40LG, HLA-B
24fibrinogen449.0CD79A, CD40LG, HLA-B
25mycophenolate mofetil44 49 1110.9CD40LG, CD79A, EPO
26doxycycline44 119.9CD40LG, CD79A, EPO
27vitamin b12448.9EPO, CD79A, CD40LG
28theophylline44 28 11 2411.9CD40LG, CD79A, EPO
29folate448.8EPO, CD79A, CD40LG
30pge2448.8HLA-B, CD40LG, CD79A, PLA2G2D
31ascorbic acid44 249.8EPO, CD79A, CD40LG
32paraffin448.5CD79A, CD40LG, HLA-B
33cyclosporin a44 28 5910.4EPO, CD79A, CD40LG, HLA-B
34lactate448.4HLA-B, CD40LG, CD79A, EPO
35creatinine448.3HLA-B, CD40LG, CD79A, EPO
36testosterone44 59 11 2411.3HLA-B, CD40LG, CD79A, EPO

GO Terms for genes affiliated with Iritis

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16Gene Ontology
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Cellular components related to Iritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058867.6SRP72, CD79A, CD40LG, PRND, HLA-B, MRAP

Biological processes related to Iritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:0301839.3CD79A, CD40LG
2B cell proliferationGO:0421009.0CD79A, CD40LG

Products for genes affiliated with Iritis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Iritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet