Aliases & Classifications for Iritis

About this section

Iritis, Aliases & Descriptions:

Name: Iritis 9 11 60


External Ids:

Disease Ontology9 DOID:1406
NCIt38 C50621
SNOMED-CT55 65074000
MeSH33 D007500

Summaries for Iritis

About this section


Wikipedia:63 Uveitis is, broadly, inflammation of the uvea. The uvea consists of the middle, pigmented vascular... more...

MalaCards based summary: Iritis is related to syphilis and inflammatory bowel disease. An important gene associated with Iritis is MRAP (melanocortin 2 receptor accessory protein), and among its related pathways are Development Angiotensin activation of ERK and B Cell Receptor Signaling Pathway. The drugs tropicamide and loteprednol etabonate and the compounds melphalan and carnitine have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and skin.

Related Diseases for Iritis

About this section

Diseases related to Iritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 102)
idRelated DiseaseScoreTop Affiliating Genes
1syphilis30.9CD79A
2inflammatory bowel disease30.0CD79A, MRAP
3nephritis29.8CD40LG, CD79A
4arthritis10.4
5spondylitis10.4
6keratitis10.4
7q fever10.4CD79A
8macroglobulinemia10.4CD79A
9cryptosporidiosis10.4CD79A
10herpes simplex10.3
11cataract10.3
12hypopyon10.3
13uveitis10.2
14blindness10.2
15rheumatoid arthritis10.2
16blau syndrome10.2
17juvenile rheumatoid arthritis10.2
18herpes zoster10.2
19diabetic autonomic neuropathy10.2
20autonomic neuropathy10.2
21colitis10.2
22conjunctivitis10.2
23neuropathy10.2
24retinitis10.2
25herpes zoster ophthalmicus10.2
26endotheliitis10.2
27norrie disease10.1
28leprosy10.1
29hepatitis10.1
30ulcerative colitis10.1
31iridocyclitis10.1
32melanoma10.1
33meningitis10.1
34myopia10.1
35pneumonia10.1
36stromal keratitis10.1
37primary hyperoxaluria10.1CD79A, EPO
38congenital toxoplasmosis10.0CD40LG, CD79A
39immunoglobulin g deficiency10.0CD79A, CD40LG
40selective iga deficiency disease10.0CD79A, CD40LG
41immunodeficiency, centromere instability and facial anomalies syndrome10.0CD40LG, CD79A
42immunoglobulin alpha deficiency10.0CD79A, CD40LG
43immunodeficiency, x-linked, with hyper-igm10.0CD79A, CD40LG
44cryoglobulinemia10.0CD40LG, CD79A
45rubella10.0CD79A, CD40LG
46pfeiffer syndrome10.0CD40LG, CD79A
47autoimmune hemolytic anemia10.0CD40LG, CD79A
48toxoplasmosis10.0CD79A, CD40LG
49agammaglobulinemia10.0CD79A, CD40LG
50common variable immunodeficiency10.0CD40LG, CD79A

Graphical network of the top 20 diseases related to Iritis:



Diseases related to iritis

Symptoms for Iritis

About this section

Drugs & Therapeutics for Iritis

About this section

Drug clinical trials:

Search ClinicalTrials for Iritis

Search NIH Clinical Center for Iritis

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Iritis

About this section

Anatomical Context for Iritis

About this section

MalaCards organs/tissues related to Iritis:

31
Eye, Testes, Skin, Endothelial, Retina

Animal Models for Iritis or affiliated genes

About this section

Publications for Iritis

About this section

Articles related to Iritis:

(show top 50)    (show all 220)
idTitleAuthorsYear
1
Intense pulsed light therapy (IPL) induced iritis following treatment for a medial canthal capillary malformation. (24417640)
2014
2
Bilateral acute pyogenic conjunctivitis with iritis induced by unilateral topical application of bacterial peptidoglycan muramyl dipeptide in adult rabbits. (24135297)
2013
3
Images in emergency medicine. Young boy with eye pain. Herpes zoster ophthalmicus, varicella zoster stromal keratitis, episcleritis and iritis. (23089088)
2012
4
Iritis and iris atrophy after eyebrow epilation with alexandrite laser. (22205833)
2011
5
Severe iritis and choroidal effusion following selective laser trabeculoplasty. (18831426)
2008
6
Latanoprost induced iritis after vitrectomy surgery. (25390234)
2007
7
Bilateral ankle edema with bilateral iritis. (16633708)
2007
8
An outbreak of iritis and uveitis in dairy cattle at pasture associated with the supplementary feeding of baleage. (16751847)
2006
9
Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis. (15327114)
2004
10
Placement of a collagen glaucoma drainage device to control intraocular pressure and chronic iritis secondary to juvenile rheumatoid arthritis. (12027105)
2002
11
Blau syndrome (familial granulomatous arthritis, iritis, and rash) in an african-american family. (19078446)
2000
12
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis. (9194724)
1997
13
Ovine iritis. (8498008)
1993
14
Acute iritis and transient renal impairment following thrombolytic therapy for acute myocardial infarction. (8305792)
1993
15
Iritis and Wells' syndrome. (1459774)
1992
16
Iritis and papillitis as a primary presentation of Lyme disease. (2310116)
1990
17
Conjunctivitis versus iritis. (2400624)
1990
18
Bovine iritis. (2756627)
1989
19
Familial granulomatous arthritis, iritis, and rash. (4056967)
1985
20
Acute interstitial nephritis and iritis. Renal-ocular syndrome. (6741981)
1984
21
Migration of acetylated hemicellulose from capillary hemodialyzer to blood, causing scleritis and/or iritis. (6508598)
1984
22
Diagnostic ultrasound in cases of acute iritis. (306769)
1978
23
Adenine arabinoside therapy in corneal stromal disease and iritis due to herpes simplex. (4359979)
1974
24
Uncommon complications of early syphilis. Hepatitis, periostitis, iritis with papillitis, and meningitis. (5015962)
1972
25
The chemotherapy of herpes iritis with adenine arabinoside and cytarabine. (4992187)
1970
26
Uveitis (iritis) associated with ulcerative and granulomatous colitis. (6018375)
1967
27
HETEROCHROMIC IRITIS AND SECONDARY NEOVASCULAR GLAUCOMA. (14129264)
1964
28
Phenylbutazone in treatment of postoperative iritis. (13813750)
1960
29
Ankylosing spondylitis and rheumatic iritis. (14415719)
1959
30
Bechcet's syndrome, aphthosis; relapsing iritis with resulting blindness; recurrent genital and oral aphthae; migrating polyarthritis; erythema nodosum; involvement of the central nervous system; nonspecific reactivity of the skin. (12996081)
1952
31
Seasonal allergic iritis; case report. (12986591)
1952
32
Posterior exudative iritis. (12996625)
1952
33
Increased intraocular pressure associated with herpes zoster ophthalmicus without any signs of iritis. (14846578)
1951
34
Recurrent aphthous ulceration of oral mucous membrane and genitals associated with recurrent hypopyon iritis (Behcet's syndrome). (20994217)
1946
35
Bilateral iritis due to sarcoidosis. (21065045)
1946
36
The role of lens substance in experimental gonorrheal iritis. (21000616)
1946
37
Syphilitic iritis with particular reference to the Herxheimer reaction as a diagnostic aid and response to different treatment including penicillin. (21006582)
1945
38
Pathology of the Lens in Non-Traumatic Iritis. (16693319)
1943
39
IRITIS IN FOWLS. (18169673)
1940
40
IRITIS (WHITE EYE) IN FOWLS: With an account of the Histological Changes in the Eye. (18169656)
1939
41
The Character of Iritis Caused by Focal Infection. (16692569)
1921
42
DISCUSSION ON THE A8TIOLOGY AND TREATMENT OF IRITIS. (20904267)
1917
43
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979874)
1917
44
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS. (19979869)
1917
45
DISCUSSION ON THE AETIOLOGY AND TREATMENT OF IRITIS: OPENING ADDRESS BY THE PRESIDENT. (19979865)
1917
46
Iritis; Some Facts of General Interest. (18736121)
1913
47
Double Tubercular Iritis. (19977296)
1913
48
THE ETIOLOGY OF IRITIS. (20765559)
1911
49
Remarks on Gonorrhoeal Iritis. (20755882)
1895
50
Iridectomy in Chronic Iritis. (16691765)
1884

Variations for Iritis

About this section

Expression for genes affiliated with Iritis

About this section
Search GEO for disease gene expression data for Iritis.

Pathways for genes affiliated with Iritis

About this section

Pathways related to Iritis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Development EDNRB signaling58
Development ACM2 and ACM4 activation of ERK58
Cell adhesion Integrin inside out signaling58
Development G Proteins mediated regulation MARK ERK signaling58
Signal transduction IP3 signaling58
Development Angiotensin signaling via PYK258
Development EPO induced MAPK pathway58
9.3CD79A, EPO
2
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
9.0CD40LG, CD79A
39.0CD40LG, CD79A

Compounds for genes affiliated with Iritis

About this section

Compounds related to Iritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
1melphalan43 49 1211.7CD79A, EPO
2carnitine439.6CD79A, EPO
3azathioprine43 2 49 1212.5CD79A, EPO
4sulfolipid i439.5CD40LG, CD79A
5sialic acid439.5EPO, CD79A
6sandoglobulin439.5CD40LG, CD79A
7gamma globulin439.5CD40LG, CD79A
8vancomycin43 1210.5CD79A, CD40LG
9pneumococcal439.5CD40LG, CD79A
10ribavirin43 49 1211.5EPO, CD40LG
11blys439.5CD40LG, CD79A
12tuberculin439.5CD79A, CD40LG
13praziquantel43 1210.5CD40LG, CD79A
14hemocyanin439.4CD40LG, CD79A
15inositol439.4CD79A, EPO
16gliadin439.4CD40LG, CD79A
17pmma439.4CD40LG, CD79A
18silicone439.4CD40LG, CD79A
19mannan439.4CD79A, CD40LG
20okt3439.4CD40LG, CD79A
21glutaraldehyde439.4CD40LG, CD79A
22sulfasalazine28 43 49 1212.4CD40LG, CD79A
23cardiolipin43 1210.4CD40LG, CD79A
24thalidomide43 49 59 1212.4EPO, CD40LG
25valproate439.4CD40LG, CD79A
26cytidine43 24 1211.4CD79A, CD40LG
27phenytoin43 49 28 1212.4CD79A, CD40LG
28anti-fungal439.4CD40LG, CD79A
29ivig439.4CD40LG, CD79A
30neopterin439.3CD40LG, CD79A
31allergens439.3CD79A, CD40LG
32rituximab43 49 1211.3CD40LG, CD79A
33polyethylene glycol439.3CD40LG, CD79A
34biotin43 24 1211.2CD40LG, CD79A
35thyroxine43 2410.1CD40LG, CD79A
36hyaluronic acid43 2410.0CD79A, CD40LG
37aspirin43 49 28 2412.0CD40LG, CD79A
38mycophenolate mofetil43 49 1211.0CD40LG, CD79A, EPO
39doxycycline43 1210.0EPO, CD79A, CD40LG
40vitamin b12439.0CD40LG, CD79A, EPO
41theophylline43 28 24 1211.9EPO, CD79A, CD40LG
42folate438.9CD40LG, CD79A, EPO
43formaldehyde43 249.9CD40LG, CD79A
44ascorbic acid43 249.9EPO, CD79A, CD40LG
45cyclosporin a43 28 5910.9EPO, CD79A, CD40LG
46lactate438.9EPO, CD79A, CD40LG
47creatinine438.9CD40LG, CD79A, EPO
48testosterone43 59 24 1211.8CD40LG, CD79A, EPO
49phosphatidylserine43 28 1210.7CD40LG, CD79A
50vegf438.7EPO, CD79A, CD40LG

GO Terms for genes affiliated with Iritis

About this section

Cellular components related to Iritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0CD40LG, CD79A

Biological processes related to Iritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:00301839.0CD40LG, CD79A
2B cell proliferationGO:00421008.7CD40LG, CD79A

Products for genes affiliated with Iritis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Iritis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet