MCID: IRN001
MIFTS: 55

Iron Deficiency Anemia

Categories: Immune diseases, Blood diseases, Metabolic diseases

Aliases & Classifications for Iron Deficiency Anemia

MalaCards integrated aliases for Iron Deficiency Anemia:

Name: Iron Deficiency Anemia 12 28 51 14 69
Iron-Deficiency Anemia 59

Classifications:



External Ids:

Disease Ontology 12 DOID:11758
ICD9CM 34 280.8
ICD10 32 D50

Summaries for Iron Deficiency Anemia

PubMed Health : 59
About iron-deficiency anemia: Iron-deficiency anemia is a common, easily treated condition that occurs if you don't have enough iron in your body. Low iron levels usually are due to blood loss, poor diet, or an inability to absorb enough iron from food.

MalaCards based summary : Iron Deficiency Anemia, also known as iron-deficiency anemia, is related to iron-refractory iron deficiency anemia and microcytic anemia. An important gene associated with Iron Deficiency Anemia is TMPRSS6 (Transmembrane Protease, Serine 6), and among its related pathways/superpathways are Insulin receptor recycling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Iron and Zinc have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Iron-deficiency anemia is anemia caused by a lack of iron. Anemia is defined as a decrease in the number... more...

Related Diseases for Iron Deficiency Anemia

Diseases related to Iron Deficiency Anemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 219)
# Related Disease Score Top Affiliating Genes
1 iron-refractory iron deficiency anemia 34.4 EPO HFE2 TMPRSS6
2 microcytic anemia 32.1 EPO SLC11A2 TF TFRC TMPRSS6
3 thalassemia 30.8 EPO HFE TF TFRC
4 iron metabolism disease 30.5 EPO HFE HFE2 SLC11A2 SLC40A1 TF
5 hyperferritinemia with or without cataract 30.1 HFE TF
6 restless legs syndrome 30.0 EPO SLC11A2 TFRC
7 hypochromic microcytic anemia 30.0 SLC11A2 TF TMPRSS6
8 polycythemia 29.9 EPO TFRC THPO
9 hemoglobinopathy 29.8 EPO HAMP HFE TF
10 thrombocytosis 29.7 CRP EPO IL6 THPO
11 dysentery 29.6 CRP LTF TF
12 castleman disease 29.5 CRP IL6
13 chronic kidney failure 29.5 CRP EPO IL6 TF
14 beta-thalassemia 29.4 EPO HAMP HFE TF TFR2 TFRC
15 intussusception 29.3 CRP IL6
16 hemosiderosis 29.0 EPO HAMP HFE SLC11A2 SLC40A1 TF
17 malaria 28.6 CRP EPO HAMP IL6 TF TFRC
18 hemochromatosis, type 1 27.5 HAMP HFE HFE2 SLC11A2 SLC40A1 TF
19 deficiency anemia 27.3 CRP EPO HAMP HFE HFE2 IL6
20 hernia, hiatus 11.3
21 gastric antral vascular ectasia 11.3
22 autoimmune atrophic gastritis 11.3
23 anemia, congenital dyserythropoietic, type iii 11.0
24 ancylostomiasis 11.0
25 iron overload in africa 10.4 HFE TF
26 aging 10.4
27 superficial siderosis of the central nervous system 10.4 LTF TF
28 superficial siderosis 10.4 LTF TF
29 splenic disease 10.4 EPO THPO
30 haemophilus influenzae 10.3 LTF TF
31 hemoglobin h disease 10.3 EPO TF TFRC
32 celiac disease 1 10.3
33 inflammatory bowel disease 10.3
34 radiation proctitis 10.3 LTF TF
35 miliary tuberculosis 10.3 CRP EPO
36 melancholia 10.3 CRP TF
37 helicobacter pylori infection 10.2
38 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.2
39 thrombosis 10.2
40 kidney disease 10.2
41 pulmonary hemosiderosis 10.2
42 cerebritis 10.2
43 gastritis 10.2
44 analbuminemia 10.1 CRP EPO TF
45 uremia 10.1 CRP EPO TF
46 hemangioma 10.1
47 hemochromatosis, type 3 10.1 HFE TFR2
48 vibrio vulnificus infection 10.1 EPO IL6
49 thrombocytopenia 10.1
50 retinitis 10.1

Comorbidity relations with Iron Deficiency Anemia via Phenotypic Disease Network (PDN): (show top 50) (show all 99)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Alcoholic Liver Cirrhosis Alzheimer Disease
Anxiety Aortic Valve Disease 1
Ascending Colon Cancer Atrophic Gastritis
Benign Essential Hypertension Bronchitis
Bronchopneumonia Cecal Benign Neoplasm
Celiac Disease 1 Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Chronic Intestinal Vascular Insufficiency Chronic Kidney Failure
Chronic Myocardial Ischemia Chylomicron Retention Disease
Colorectal Cancer Conjunctivitis
Cystitis Decubitus Ulcer
Deficiency Anemia Dermatomycosis
Duodenitis Dysthymic Disorder
Encephalopathy Esophageal Candidiasis
Esophageal Disease Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Folic Acid Deficiency Anemia Gastric Cancer
Gastrointestinal System Cancer Generalized Atherosclerosis
Gout Heart Disease
Hepatic Flexure Cancer Hydronephrosis
Hypersplenism Hypertension, Essential
Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome Hypoglycemia
Hypoglycemic Coma Hypothyroidism

Graphical network of the top 20 diseases related to Iron Deficiency Anemia:



Diseases related to Iron Deficiency Anemia

Symptoms & Phenotypes for Iron Deficiency Anemia

MGI Mouse Phenotypes related to Iron Deficiency Anemia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 THPO LTF SLC11A2 EPO SLC40A1 HFE
2 homeostasis/metabolism MP:0005376 10.07 THPO LTF CRP SLC11A2 EPO SLC40A1
3 cardiovascular system MP:0005385 9.97 CRP SLC11A2 EPO SLC40A1 HFE2 TFRC
4 immune system MP:0005387 9.93 THPO LTF CRP SLC11A2 EPO SLC40A1
5 integument MP:0010771 9.5 SLC11A2 EPO SLC40A1 HFE2 TFRC IL6
6 liver/biliary system MP:0005370 9.32 LTF SLC11A2 EPO SLC40A1 HFE HFE2

Drugs & Therapeutics for Iron Deficiency Anemia

PubMedHealth treatment related to Iron Deficiency Anemia: 59

Treatment for iron-deficiency anemia will depend on its cause and severity. Treatments may include dietary changes and supplements, medicines, and surgery.Severe iron-deficiency anemia may require a blood transfusion, iron injections, or intravenous (IV) iron therapy. Treatment may need to be done in a hospital.The goals of treating iron-deficiency anemia are to treat its underlying cause and restore normal levels of red blood cells, hemoglobin, and iron.

Drugs for Iron Deficiency Anemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 265)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
2
Zinc Approved, Investigational Phase 4,Phase 3,Early Phase 1 7440-66-6 32051 23994
3
Halofantrine Approved Phase 4 69756-53-2 37393
4
Copper Approved, Investigational Phase 4,Phase 3 7440-50-8 27099
5
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 5460373 44475014 11953898
6
Iodine Approved, Investigational Phase 4,Phase 3 7553-56-2 807
7
Selenium Approved, Investigational, Vet_approved Phase 4,Phase 3 7782-49-2
8
Metronidazole Approved Phase 4 443-48-1 4173
9
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
10
Clarithromycin Approved Phase 4 81103-11-9 84029
11
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
12
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 68-26-8, 11103-57-4 445354
13
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1 50-81-7 54670067 5785
14
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 59-30-3 6037
15
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1 58-05-9 143 6006
16
Glycine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 56-40-6 750
17
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 10883523 5280795 6221
18
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 68-19-9 44176380
19
Methylcobalamin Approved, Experimental, Investigational, Nutraceutical Phase 4,Phase 2,Phase 3 13422-55-4
20
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3 59-67-6 938
21
Nicotinamide Approved, Investigational, Nutraceutical Phase 4,Phase 3 98-92-0 936
22
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3 66-72-8 1050
23
Pyridoxine Approved, Investigational, Nutraceutical, Vet_approved Phase 4,Phase 3 65-23-6 1054
24
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 4,Phase 3 83-88-5 493570
25
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 4,Phase 3 59-43-8 1130
26 Tocopherol Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 1
27
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 1406-16-2
28
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1 59-02-9 14985
29
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 77-92-9 311
30
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
31 Ferric Compounds Phase 4,Phase 3,Phase 2,Phase 1
32 Ferric oxide, saccharated Phase 4,Phase 2,Phase 3,Phase 1
33 Hematinics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
35 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Teferrol Phase 4,Phase 3
37 Retinol palmitate Phase 4,Phase 3,Phase 2,Early Phase 1
38 Vitamins Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Ferrous gluconate Phase 4,Phase 1
40 Ferrous fumarate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Ferrosoferric Oxide Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
42 Parenteral Nutrition Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
44 Epoetin alfa Phase 4,Phase 2,Phase 3,Phase 1 113427-24-0
45 ferric gluconate Phase 4,Phase 2,Phase 3,Phase 1
46 Vitamin B Complex Phase 4,Phase 2,Phase 3,Phase 1
47 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
48 Hepcidins Phase 4,Phase 1,Phase 2
49 Anticoagulants Phase 4,Phase 3,Phase 2,Phase 1
50 Blood Substitutes Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 527)

# Name Status NCT ID Phase Drugs
1 Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate. Unknown status NCT00199277 Phase 4 i.v. iron sucrose;Oral iron
2 Prevention of Iron Deficiency in 2nd Year of Life Unknown status NCT00479102 Phase 4 Ferripel-3 - iron polysaccharide complex for prevention
3 Different Iron Supplements for Prevention of Anemia in Pregnancy Unknown status NCT02487719 Phase 4 Iron sulfate and Iron polymaltose for prevention of iron deficiency anemia
4 Nutrient Fortified Oat Drink Unknown status NCT01418898 Phase 4
5 Iron Deficiency In Pulmonary Hypertension Unknown status NCT01288651 Phase 4 Ferricarboxymaltose
6 Effect Of Intravenous Iron Versus Placebo On Muscle Oxidative Capacity And Physical Performance In Non Anemic Premenopausal Women With Low Ferritin Levels Unknown status NCT01374776 Phase 4 Double blind, randomized, placebo controlled inter
7 Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations. Unknown status NCT00248716 Phase 4 Ferrous gluconate and iron polysaccharide complex
8 Iron Supplementation of Marginally Low Birth Weight Infants Unknown status NCT00558454 Phase 4 Iron
9 Iron Absorption Trial Unknown status NCT02228902 Phase 4 Ferrous fumarate;Ferrous gluconate
10 Prevention of Iron Deficiency in Breastfed Infants Completed NCT01444261 Phase 4
11 Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy Completed NCT02086838 Phase 4 Theragran Hematinic;low molecular weight iron dextran
12 Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia Completed NCT01904864 Phase 4 elemental iron (NovaFerrum®);elemental iron (Ferrous Sulfate)
13 Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies Completed NCT01221844 Phase 4 FerroGrad by Abbott
14 Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy Completed NCT01245777 Phase 4 ferric carboxymaltose
15 A Phase IV Trial of Repeated Doses of Ferumoxytol Compared to Iron Sucrose for the Treatment of Iron Deficiency Anemia in Patients With Chronic Kidney Disease on Hemodialysis Completed NCT01227616 Phase 4 Ferumoxytol;Iron Sucrose
16 A Trial of Iron Replacement in Patients With Iron Deficiency. Completed NCT01067547 Phase 4 Iron Sucrose.;Iron sucrose
17 Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin Completed NCT00802139 Phase 4 venoferrum(iron sucrose);Bolgre (Iron acetyl-transferase)
18 Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate Completed NCT01991314 Phase 4 Ferrous sulphate
19 A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency Completed NCT01453608 Phase 4 Ferinject (ferric carboxymaltose);Placebo (saline)
20 Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients Completed NCT01942460 Phase 4 Ferumoxytol
21 Study of the Efficacy of Two Doses of Ferrlecit in the Treatment of Iron Deficiency in Pediatric Hemodialysis Patients Completed NCT00223964 Phase 4 Ferrlecit (sodium ferric gluconate complex in sucrose injection)
22 Iron Indices and Intravenous Ferumoxytol: Time to Steady State Completed NCT01148745 Phase 4 ferumoxytol
23 Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure Completed NCT01922479 Phase 4 Ferric Carboxymaltose;Placebo
24 Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron. Completed NCT02392910 Phase 4 Iron Sucrose;Placebo
25 Iron Substitution in Blood Donors Completed NCT01519830 Phase 4 Iron carboxymaltose (Ferinject);Placebo
26 Endovenous Versus Liposomal Iron in CKD Completed NCT01864161 Phase 4 gluconate iron;Liposomal iron
27 Short-Term Effects & Safety of an Accelerated Intravenous Iron Regimen in Patients With Heart Failure Completed NCT01925703 Phase 4 Sodium ferric gluconate
28 Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age Completed NCT01110356 Phase 4 Ferinject
29 Intravenous Treatment of Anemia in Pregnancy Completed NCT03317210 Phase 4 iron sucrose (200 mg VENOFER®);recombinant human erythropoietin (10,000 U EPREX®)
30 Effectiveness of Adaptation of the Dose of Iron Supplementation in Pregnancy on Maternal-child Health. (ECLIPSES) Completed NCT03196882 Phase 4 40mg/day of iron;20mg/day of iron;80mg/day of iron
31 Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya Completed NCT01088958 Phase 4
32 Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment Completed NCT00746551 Phase 4 Ferli-6® (Continental Pharm co., ltd.);Venofer® (Vifor AG, St. Gallen, Switzerland)
33 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Completed NCT00224055 Phase 4 Sodium Ferric Gluconate Complex in Sucrose Injection;Ferrous sulfate tablets
34 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents Completed NCT00224042 Phase 4 Sodium Ferric Gluconate complex in sucrose;Ferrous sulfate tablets
35 Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors Completed NCT00689793 Phase 4 Ferrous sulphate;Placebo
36 DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin) Completed NCT00224081 Phase 4 Sodium ferric gluconate,
37 Switch From Oral Iron to Intravenous Ferric Carboxymaltose in Non-dialysis Chronic Kidney Disease (CKD) Completed NCT02232906 Phase 4 intravenous ferric carboxymaltose
38 Effect of Two Iron Preparations on Protein in the Urine Completed NCT00354692 Phase 4 Sodium Ferric Gluconate and Iron sucrose
39 Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study) Completed NCT01609387 Phase 4
40 Efficacy of Intravenous Iron Administration in Hemodialysis Patients Completed NCT00298441 Phase 4 chondroitin sulfate-iron colloid
41 Periodic Versus Continuous IV Iron Supplementation in HD Patients Completed NCT02787824 Phase 4 Iron Sucrose Supplement
42 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
43 The Use of Liposomated Iron After Bariatric Surgery in Patients That Are Receiving Parentheral Therapy With Iron Completed NCT02390921 Phase 4 Fisiogen Ferro Forte;Venofer
44 Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination Completed NCT00677794 Phase 4 Clear fluids;Picosalax;Polyethylene glycol
45 Effect of Iron Therapy as an Adjunct to Epoetin Alfa in the Anemia of Cancer Chemotherapy Completed NCT00224068 Phase 4 Sodium ferric gluconate, ferrous sulfate, standard of care
46 Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD Recruiting NCT02774057 Phase 4 Captafer®;Iron Sulfate
47 Iron Treatment for Young Children With Non-anemic Iron Deficiency Recruiting NCT01481766 Phase 4
48 Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome. Recruiting NCT02031289 Phase 4 Erythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
49 Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy Recruiting NCT03202615 Phase 4 F (ferrous sulphate)
50 Iron Deficiency Anemia, Iron Supplementation and Genomic Stability in Infants Recruiting NCT03359447 Phase 4 Weekly Ferrous Sulfate;Daily Ferrous Sulfate

Search NIH Clinical Center for Iron Deficiency Anemia

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Iron Deficiency Anemia

Genetic tests related to Iron Deficiency Anemia:

# Genetic test Affiliating Genes
1 Iron Deficiency Anemia 28

Anatomical Context for Iron Deficiency Anemia

MalaCards organs/tissues related to Iron Deficiency Anemia:

38
Heart, Kidney, Testes, Brain, Breast, Skeletal Muscle, Bone

Publications for Iron Deficiency Anemia

Articles related to Iron Deficiency Anemia:

(show top 50) (show all 791)
# Title Authors Year
1
Pharmacokinetics, pharmacodynamics, safety, and tolerability of intravenous ferric carboxymaltose: a dose-escalation study in Japanese volunteers with iron-deficiency anemia. ( 29357079 )
2018
2
Lactoferrin plus health education versus total dose infusion (TDI) of low-molecular weight (LMW) iron dextran for treating iron deficiency anemia (IDA) in pregnancy: a randomized controlled trial. ( 29338568 )
2018
3
Assessment of peripheral blood lymphocyte subsets in children with iron deficiency anemia. ( 29433459 )
2018
4
Comments on: Prognostic impact of anemia and iron-deficiency anemia in a contemporary cohort of patients undergoing transcatheter aortic valve implantation. ( 29407119 )
2018
5
Should asymptomatic young men with iron deficiency anemia necessarily undergo endoscopy? ( 29294595 )
2018
6
Capsule Endoscopy for Refractory Iron Deficiency Anemia in Crohn's Disease: Captivating Pathology, Hybrid Therapy. ( 29409826 )
2018
7
Association Between Iron-Deficiency Anemia and Hypophosphatemia. ( 29031590 )
2018
8
Relationship between obesity and iron deficiency anemia: is there a role of hepcidin? ( 29318945 )
2018
9
Comparative safety of intravenous ferumoxytol vs ferric carboxymaltose in iron deficiency anemia: A randomized trial. ( 29417614 )
2018
10
Aggregation-Induced Emission Probe for Specific Turn-On Quantification of Soluble Transferrin Receptor: An Important Disease Marker for Iron Deficiency Anemia and Kidney Diseases. ( 29271190 )
2018
11
Iron deficiency and iron deficiency anemia in children aged 6-36 months: Is there room for improvement of screening, prophylaxis and treatment? ( 29258914 )
2018
12
Celiac Disease in Children with Moderate-to-Severe Iron-deficiency Anemia. ( 29396932 )
2018
13
Development of probiotic formulation for the treatment of iron deficiency anemia. ( 29353864 )
2018
14
Microcytosis is important in screening of iron deficiency anemia. ( 29361474 )
2018
15
Effectiveness and safety of ferric carboxymaltose compared to iron sucrose in women with iron deficiency anemia: phase IV clinical trials. ( 29304848 )
2018
16
Efficacy and safety of IV ferumoxytol for iron deficiency anemia in patients with cancer. ( 29263710 )
2017
17
Electrophysiological changes of autonomic cells in left ventricular outflow tract in guinea pigs with iron deficiency anemia complicated with chronic heart failure. ( 29268978 )
2017
18
Erythroferrone and iron status parameters levels in pediatric patients with iron deficiency anemia. ( 29282766 )
2017
19
Comment: Intravenous Ferumoxytol in Pediatric Patients With Iron Deficiency Anemia. ( 28925297 )
2017
20
Helicobacter pylori sabA gene is associated with iron deficiency anemia in childhood and adolescence. ( 28854239 )
2017
21
Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study. ( 28073037 )
2017
22
Preoperative management of colorectal cancer-induced iron deficiency anemia in clinical practice: data from a large observational cohort. ( 28833205 )
2017
23
Sodium chloride pica causing recurrent nephrolithiasis in a patient with iron deficiency anemia: a case report. ( 29149910 )
2017
24
Idiopathic Pulmonary Hemosiderosis Mimicking Iron Deficiency Anemia: A Delayed Diagnosis? ( 28670434 )
2017
25
A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. ( 28052413 )
2017
26
VON WILLEBRAND FACTOR IMMUNOHISTOCHEMICAL STAINING QUANTITATIVE OPTICAL DENSITY PARAMETERS IN THE ENDOTHELIUM AND FIBRINOID OF THE PLACENTA DURING SECUNDINES INFLAMMATION AND CONCOMITANT IRON DEFICIENCY ANEMIA IN GRAVIDAS. ( 29328041 )
2017
27
Author's reply: Directly observed iron supplementation for control of iron deficiency anemia. ( 28928309 )
2017
28
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population. ( 28492865 )
2017
29
Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child. ( 28460265 )
2017
30
Prevalence of Iron Deficiency and Iron Deficiency Anemia in the Northern and Southern Provinces of Rwanda. ( 28826251 )
2017
31
Challenges in the diagnosis of iron deficiency anemia in aged people. ( 28830594 )
2017
32
Relationship between iron deficiency anemia and febrile seizures in children: A systematic review and meta-analysis. ( 28957722 )
2017
33
Iron deficiency anemia and Plummer-Vinson syndrome: current insights. ( 29089792 )
2017
34
The DMT1 IVS4+44C>A polymorphism and the risk of iron deficiency anemia in children with celiac disease. ( 29023457 )
2017
35
Phase III randomized trial comparing intravenous to oral iron in patients with cancer-related iron deficiency anemia not on erythropoiesis stimulating agents. ( 28849623 )
2017
36
Assessment of the Matos & Carvalho index for distinguishing thalassemia from iron deficiency anemia. ( 28830614 )
2017
37
A budget impact analysis of parenteral iron treatments for iron deficiency anemia in the UK: reduced resource utilization with iron isomaltoside 1000. ( 28848355 )
2017
38
Effects of Ferric Citrate in Patients with Nondialysis-Dependent CKD and Iron Deficiency Anemia. ( 28082519 )
2017
39
New Bioinformatics-Based Discrimination Formulas for Differentiation of Thalassemia Traits From Iron Deficiency Anemia. ( 28934514 )
2017
40
Total dose iron dextran infusion versus oral iron for treating iron deficiency anemia in pregnant women: a randomized controlled trial. ( 28901214 )
2017
41
Comparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemia. ( 28872486 )
2017
42
QUANTITATIVE ASSESSMENT OF THE RESULTS OF VIMENTIN IMMUNOHISTOCHEMICAL EXAMINATION IN FIBROBLASTS AND ENDOTHELIOCYTES OF THE PLACENTAL VILLI IN THE ASPECT OF PRETERM MATURATION OF THE CHORIONIC TREE AND IRON DEFICIENCY ANEMIA OF GRAVIDAS. ( 29328038 )
2017
43
Delusional parasitosis secondary to severe iron deficiency anemia. ( 28879221 )
2017
44
Reply: Intravenous Ferumoxytol in Pediatric Patients With Iron-Deficiency Anemia. ( 28831808 )
2017
45
Ability of serum ferritin to diagnose iron deficiency anemia in an elderly cohort. ( 28830601 )
2017
46
Curative resectability of gastrointestinal cancer identified from iron deficiency anemia. ( 28943943 )
2017
47
Cerebral Venous Thrombosis in a Patient with Iron Deficiency Anemia and Thrombocytopenia: A Case Report. ( 29362628 )
2017
48
Primary care physicians are under-testing for celiac disease in patients with iron deficiency anemia: Results of a national survey. ( 28931034 )
2017
49
Iron Refractory Iron Deficiency Anemia in Dizygotic Twins Due to a Novel TMPRSS6 Gene Mutation in Addition to Polymorphisms Associated With High Susceptibility to Develop Ferropenic Anemia. ( 28491880 )
2017
50
Enhanced nickel sensitivity in iron deficiency anemia. ( 28928308 )
2017

Variations for Iron Deficiency Anemia

Expression for Iron Deficiency Anemia

Search GEO for disease gene expression data for Iron Deficiency Anemia.

Pathways for Iron Deficiency Anemia

GO Terms for Iron Deficiency Anemia

Cellular components related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasmic vesicle GO:0031410 9.83 HFE SLC11A2 TF TFR2 TFRC
2 cell surface GO:0009986 9.73 EPO HFE2 LTF SLC11A2 TF TFRC
3 extracellular space GO:0005615 9.7 CRP EPO HAMP HFE HFE2 IL6
4 early endosome GO:0005769 9.67 HFE SLC11A2 TF TFRC
5 recycling endosome GO:0055037 9.62 HFE SLC11A2 TF TFRC
6 basal part of cell GO:0045178 9.33 HFE SLC11A2 TF
7 HFE-transferrin receptor complex GO:1990712 9.02 HFE HFE2 TF TFR2 TFRC
8 extracellular region GO:0005576 10.01 CRP EPO HAMP IL6 LTF TF

Biological processes related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.93 HFE LTF SLC11A2 SLC40A1 TF
2 regulation of receptor activity GO:0010469 9.87 EPO HAMP IL6 THPO
3 transferrin transport GO:0033572 9.71 HFE TF TFR2 TFRC
4 response to iron ion GO:0010039 9.67 HAMP HFE SLC11A2 TFR2
5 acute-phase response GO:0006953 9.63 CRP EPO HAMP HFE IL6 TFR2
6 iron ion transport GO:0006826 9.62 SLC11A2 SLC40A1 TF TFR2
7 cellular response to iron ion GO:0071281 9.61 HFE TF TFR2
8 cellular iron ion homeostasis GO:0006879 9.61 HAMP HFE HFE2 SLC11A2 SLC40A1 TF
9 positive regulation of receptor-mediated endocytosis GO:0048260 9.56 HFE TF
10 multicellular organismal iron ion homeostasis GO:0060586 9.56 HAMP HFE SLC11A2 SLC40A1
11 response to vitamin A GO:0033189 9.55 EPO HAMP
12 negative regulation of lipid storage GO:0010888 9.52 CRP IL6
13 positive regulation of peptide hormone secretion GO:0090277 9.51 HFE TFR2
14 iron ion transmembrane transport GO:0034755 9.49 SLC11A2 SLC40A1
15 response to iron ion starvation GO:1990641 9.48 HAMP HFE
16 ferrous iron import across plasma membrane GO:0098707 9.46 TF TFR2
17 iron ion homeostasis GO:0055072 9.23 HFE HFE2 LTF SLC11A2 SLC40A1 TF

Molecular functions related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.58 EPO HAMP THPO
2 co-receptor binding GO:0039706 9.37 HFE TFR2
3 iron ion transmembrane transporter activity GO:0005381 9.32 SLC11A2 SLC40A1
4 ferrous iron transmembrane transporter activity GO:0015093 9.26 SLC11A2 SLC40A1
5 transferrin transmembrane transporter activity GO:0033570 9.16 TFR2 TFRC
6 transferrin receptor activity GO:0004998 8.96 TFR2 TFRC
7 transferrin receptor binding GO:1990459 8.8 HFE HFE2 TF

Sources for Iron Deficiency Anemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....