MCID: IRN001
MIFTS: 52

Iron Deficiency Anemia malady

Categories: Immune diseases, Blood diseases, Metabolic diseases

Aliases & Classifications for Iron Deficiency Anemia

Aliases & Descriptions for Iron Deficiency Anemia:

Name: Iron Deficiency Anemia 12 29 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11758
ICD9CM 35 280.8
ICD10 33 D50
UMLS 69 C0029810

Summaries for Iron Deficiency Anemia

MalaCards based summary : Iron Deficiency Anemia is related to atherosclerosis and neuropathy. An important gene associated with Iron Deficiency Anemia is TMPRSS6 (Transmembrane Protease, Serine 6), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and HIF-1 signaling pathway. The drugs Zinc and Iron have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 71 Iron-deficiency anemia, also spelled iron-deficiency anaemia,[help 1] is anemia caused by a lack of... more...

Related Diseases for Iron Deficiency Anemia

Diseases related to Iron Deficiency Anemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
id Related Disease Score Top Affiliating Genes
1 atherosclerosis 29.5 EPO IL6
2 neuropathy 29.2 CRP IL6 THPO
3 iron-refractory iron deficiency anemia 12.5
4 microcytic anemia 11.4
5 autoimmune atrophic gastritis 11.2
6 plummer vinson syndrome 11.2
7 gastric antral vascular ectasia 11.2
8 deficiency anemia 11.1
9 iron metabolism disease 11.0
10 hiatus hernia 10.9
11 thalassemia 10.4
12 dermatoleukodystrophy 10.3 HFE TF
13 sutton disease 2 10.2 LTF TF
14 rosette-forming glioneuronal tumor of fourth ventricule 10.2 LTF TF
15 inflammatory bowel disease 10.2
16 thrombocytosis 10.2
17 thalassemia minor 10.2
18 celiac disease 10.2
19 intestinal impaction 10.1 EPO TFRC THPO
20 villonodular synovitis 10.1 CRP EPO
21 thrombosis 10.1
22 retinal arterial macroaneurysm with supravalvular pulmonic stenosis 10.1 CRP EPO TF
23 spinocerebellar ataxia 18 10.1 HFE TFR2
24 hemosiderosis 10.1
25 gastritis 10.1
26 kidney disease 10.1
27 bile duct mucoepidermoid carcinoma 10.1 CRP EPO TF
28 vitamin a embryopathy 10.1 EPO IL6
29 pulmonary hemosiderosis 10.1
30 hemangioma 10.1
31 cerebritis 10.1
32 harp syndrome 10.1 CRP HFE TF
33 larynx sarcoma 10.1 EPO HAMP HFE TF
34 tmem216-related meckel syndrome 10.1 EPO HFE TF TFRC
35 spastic entropion 10.0 CRP LTF TF
36 retinitis 10.0
37 epileptic encephalopathy, early infantile, 13 10.0 HAMP SLC11A2 TF TMPRSS6
38 tmem231-related joubert syndrome 10.0 HAMP HFE TF TFRC
39 optic atrophy 5 10.0 EPO HFE2 TMPRSS11A TMPRSS6
40 hemoglobin c disease 10.0 CRP TF
41 thrombocytopenia 10.0
42 kaolin pneumoconiosis 10.0 HFE LTF TF TFRC
43 coloboma of iris 10.0 CRP IL6
44 psychotic disorder 10.0 IL6 LTF
45 cutaneous sclerosis 10.0 CRP IL6
46 shoulder impingement syndrome 9.9 CRP IL6
47 obesity 9.9
48 duodenitis 9.9
49 cavernous hemangioma 9.9
50 papilledema 9.9

Comorbidity relations with Iron Deficiency Anemia via Phenotypic Disease Network (PDN): (show top 50) (show all 98)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Alcoholic Liver Cirrhosis Alzheimer Disease
Anxiety Disorder Aplastic Anemia
Ascending Colon Cancer Atrophic Gastritis
Benign Essential Hypertension Bronchitis
Bronchopneumonia Cecal Benign Neoplasm
Celiac Disease Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Chronic Kidney Failure Chronic Myocardial Ischemia
Chylomicron Retention Disease Colorectal Cancer
Conjunctivitis Cystitis
Decubitus Ulcer Deficiency Anemia
Dermatomycosis Duodenitis
Dysthymic Disorder Encephalopathy
Esophageal Candidiasis Esophageal Disease
Esophagitis Familial Atrial Fibrillation
First-Degree Atrioventricular Block Folic Acid Deficiency Anemia
Gastric Cancer, Somatic Gastrointestinal System Cancer
Generalized Atherosclerosis Gout
Heart Disease Hepatic Flexure Cancer
Hydronephrosis Hypersplenism
Hypertension, Essential Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis
Hypoglycemia Hypoglycemic Coma
Hypothyroidism Inflammatory Bowel Disease 1

Graphical network of the top 20 diseases related to Iron Deficiency Anemia:



Diseases related to Iron Deficiency Anemia

Symptoms & Phenotypes for Iron Deficiency Anemia

MGI Mouse Phenotypes related to Iron Deficiency Anemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 EPO HFE HFE2 IL6 LTF SLC11A2
2 homeostasis/metabolism MP:0005376 9.93 TF TFR2 TFRC THPO TMPRSS6 CRP
3 immune system MP:0005387 9.7 CRP EPO HFE HFE2 IL6 LTF
4 liver/biliary system MP:0005370 9.28 EPO HFE HFE2 IL6 LTF SLC11A2

Drugs & Therapeutics for Iron Deficiency Anemia

Drugs for Iron Deficiency Anemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 268)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc Approved Phase 4,Phase 3,Early Phase 1 7440-66-6 32051 23994
2
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 11953898 5460373 44475014
5
Copper Approved Phase 4,Phase 3,Phase 2 15158-11-9, 7440-50-8 27099
6
Selenium Approved, Vet_approved Phase 4,Phase 3 7782-49-2
7
Metronidazole Approved Phase 4 443-48-1 4173
8
Halofantrine Approved Phase 4 69756-53-2 37393
9
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 11103-57-4, 68-26-8 445354
10
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
11
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1 50-81-7 5785 54670067
12
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 2 67-97-0 6221 10883523 5280795
13
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2 50-14-6 5280793
14
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
15
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 68-19-9 44176380
16
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 65-23-6 1054
17
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2 59-67-6 938
18
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 83-88-5 493570
19
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2 98-92-0 936
20
Thiamine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-43-8 1130
21
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3,Phase 2 66-72-8 1050
22
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1 59-02-9 14985
23 vitamin d Phase 4,Phase 3,Phase 2
24 ferric gluconate Phase 4,Phase 2,Phase 3,Phase 1
25 Epoetin alfa Phase 4,Phase 2,Phase 3,Phase 1 113427-24-0
26
Proton pump inhibitors Phase 4
27 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
28 Teferrol Phase 4,Phase 3
29 Hematinics Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
30 Hepcidins Phase 4,Phase 2,Phase 1
31 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Dextrans Phase 4,Phase 3,Phase 2,Phase 1
33 Parenteral Nutrition Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Vitamin B 12 Phase 4,Phase 2,Phase 3
35 Vitamin B Complex Phase 4,Phase 3,Phase 2,Phase 1
36 Antacids Phase 4,Phase 2,Phase 3,Phase 1
37 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
38 Ergocalciferols Phase 4,Phase 2
39 Vitamins Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Plasma Substitutes Phase 4,Phase 3,Phase 2
41 Anti-Infective Agents Phase 4,Phase 3,Phase 2
42 Ferric Compounds Phase 4,Phase 3,Phase 2,Phase 1
43 Ferric oxide, saccharated Phase 4,Phase 2,Phase 3,Phase 1
44 Ferrosoferric Oxide Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
45 Ferrous fumarate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Ferrous gluconate Phase 4,Phase 1
47 Anticoagulants Phase 4,Phase 3,Phase 2,Phase 1
48 Iron-Dextran Complex Phase 4,Phase 3,Phase 2,Phase 1
49 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3,Phase 1
50 Retinol palmitate Phase 4,Phase 3,Phase 2,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 502)
id Name Status NCT ID Phase
1 Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia Unknown status NCT01904864 Phase 4
2 Prevention of Iron Deficiency in 2nd Year of Life Unknown status NCT00479102 Phase 4
3 Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate. Unknown status NCT00199277 Phase 4
4 Different Iron Supplements for Prevention of Anemia in Pregnancy Unknown status NCT02487719 Phase 4
5 Capsule Endoscopy vs Standard of Care for Obscure Intestinal Bleeding Unknown status NCT00694954 Phase 4
6 Nutrient Fortified Oat Drink Unknown status NCT01418898 Phase 4
7 Iron Deficiency In Pulmonary Hypertension Unknown status NCT01288651 Phase 4
8 Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations. Unknown status NCT00248716 Phase 4
9 Effect Of Intravenous Iron Versus Placebo On Muscle Oxidative Capacity And Physical Performance In Non Anemic Premenopausal Women With Low Ferritin Levels Unknown status NCT01374776 Phase 4
10 Iron Supplementation of Marginally Low Birth Weight Infants Unknown status NCT00558454 Phase 4
11 Iron Absorption Trial Unknown status NCT02228902 Phase 4
12 Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC Unknown status NCT01795794 Phase 4
13 Prevention of Iron Deficiency in Breastfed Infants Completed NCT01444261 Phase 4
14 Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy Completed NCT01245777 Phase 4
15 A Trial of Iron Replacement in Patients With Iron Deficiency. Completed NCT01067547 Phase 4
16 Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy Completed NCT02086838 Phase 4
17 Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies Completed NCT01221844 Phase 4
18 A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency Completed NCT01453608 Phase 4
19 Study of the Efficacy of Two Doses of Ferrlecit in the Treatment of Iron Deficiency in Pediatric Hemodialysis Patients Completed NCT00223964 Phase 4
20 Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin Completed NCT00802139 Phase 4
21 Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate Completed NCT01991314 Phase 4
22 Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure Completed NCT01922479 Phase 4
23 Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya Completed NCT01088958 Phase 4
24 Iron Substitution in Blood Donors Completed NCT01519830 Phase 4
25 Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients Completed NCT01942460 Phase 4
26 Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron. Completed NCT02392910 Phase 4
27 Iron Indices and Intravenous Ferumoxytol: Time to Steady State Completed NCT01148745 Phase 4
28 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Completed NCT00224055 Phase 4
29 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents Completed NCT00224042 Phase 4
30 Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age Completed NCT01110356 Phase 4
31 Endovenous Versus Liposomal Iron in CKD Completed NCT01864161 Phase 4
32 Short-Term Effects & Safety of an Accelerated Intravenous Iron Regimen in Patients With Heart Failure Completed NCT01925703 Phase 4
33 Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors Completed NCT00689793 Phase 4
34 Effect of Two Iron Preparations on Protein in the Urine Completed NCT00354692 Phase 4
35 Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment Completed NCT00746551 Phase 4
36 DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin) Completed NCT00224081 Phase 4
37 Switch From Oral Iron to Intravenous Ferric Carboxymaltose in Non-dialysis Chronic Kidney Disease (CKD) Completed NCT02232906 Phase 4
38 Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study) Completed NCT01609387 Phase 4
39 Efficacy of Intravenous Iron Administration in Hemodialysis Patients Completed NCT00298441 Phase 4
40 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
41 The Use of Liposomated Iron After Bariatric Surgery in Patients That Are Receiving Parentheral Therapy With Iron Completed NCT02390921 Phase 4
42 Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination Completed NCT00677794 Phase 4
43 Effect of Iron Therapy as an Adjunct to Epoetin Alfa in the Anemia of Cancer Chemotherapy Completed NCT00224068 Phase 4
44 Iodine Status of Preschoolers Given Micronutrient Powder for 6 Months Completed NCT02280330 Phase 4
45 Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS) Completed NCT00944281 Phase 4
46 Iron Treatment for Young Children With Non-anemic Iron Deficiency Recruiting NCT01481766 Phase 4
47 Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome. Recruiting NCT02031289 Phase 4
48 Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality Recruiting NCT03036462 Phase 4
49 Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD Recruiting NCT02774057 Phase 4
50 the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients Recruiting NCT02631668 Phase 4

Search NIH Clinical Center for Iron Deficiency Anemia

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Iron Deficiency Anemia

Genetic tests related to Iron Deficiency Anemia:

id Genetic test Affiliating Genes
1 Iron Deficiency Anemia 29

Anatomical Context for Iron Deficiency Anemia

MalaCards organs/tissues related to Iron Deficiency Anemia:

39
Kidney, Heart, Testes, Colon, Small Intestine, Neutrophil, Placenta

Publications for Iron Deficiency Anemia

Articles related to Iron Deficiency Anemia:

(show top 50) (show all 745)
id Title Authors Year
1
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population. ( 28492865 )
2017
2
A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. ( 28052413 )
2017
3
Effects of Ferric Citrate in Patients with Nondialysis-Dependent CKD and Iron Deficiency Anemia. ( 28082519 )
2017
4
Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child. ( 28460265 )
2017
5
Iron Refractory Iron Deficiency Anemia in Dizygotic Twins Due to a Novel TMPRSS6 Gene Mutation in Addition to Polymorphisms Associated With High Susceptibility to Develop Ferropenic Anemia. ( 28491880 )
2017
6
Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study. ( 28073037 )
2017
7
Iron Refractory Iron Deficiency Anemia (IRIDA): A heterogeneous disease that is not always iron refractory. ( 27643674 )
2016
8
Iron deficiency anemia due to excessive green tea drinking. ( 27830072 )
2016
9
Iron-Refractory Iron Deficiency Anemia May Not Lead to Neurocognitive Dysfunction: A Case Report. ( 27365303 )
2016
10
Evaluation of Choroidal Thickness in Children With Iron Deficiency Anemia. ( 27806382 )
2016
11
Gastric inverted hyperplastic polyp: A rare cause of iron deficiency anemia. ( 27099452 )
2016
12
Iron Deficiency Anemia: Problems in Diagnosis and Prevention at the Population Level. ( 27040956 )
2016
13
Abdominal aortic thrombosis secondary to reactive thrombocytosis in a patient with iron deficiency anemia. ( 27256347 )
2016
14
Gastroduodenal lesions in iron-deficiency anemia. ( 27852537 )
2016
15
Iron deficiency, anemia, and mortality in renal transplant recipients. ( 27516242 )
2016
16
Evaluation of left atrial function in patients with iron-deficiency anemia by two-dimensional speckle tracking echocardiography. ( 27550185 )
2016
17
Iron deficiency anemia in the emergency department: over-utilization of red blood cell transfusion and infrequent use of iron supplementation. ( 27819205 )
2016
18
Oral Submucous Fibrosis Secondary to Iron Deficiency Anemia: A Case Report, Etiopathogenesis and Management. ( 26812518 )
2016
19
A 5-Year Follow-Up of Study Patients With Asymptomatic Iron-Deficiency Anemia Using a Nurse-Led Pathway. ( 27922517 )
2016
20
A comprehensive evaluation of the gastrointestinal tract in iron-deficiency anemia with predefined hemoglobin below 9mg/dL: A prospective cohort study. ( 28065528 )
2016
21
Resolution of constipation, anal stricture, and iron deficiency anemia after iron infusion: an analogy with Plummer Vinson syndrome. ( 27917348 )
2016
22
Cost-Effectiveness of Price Subsidies on Fortified Packaged Infant Cereals in Reducing Iron Deficiency Anemia in 6-23-Month-Old-Children in Urban India. ( 27073892 )
2016
23
Ferumoxytol versus placebo in iron deficiency anemia: efficacy, safety, and quality of life in patients with gastrointestinal disorders. ( 27468245 )
2016
24
Absolute Reticulocyte Count and Reticulocyte Hemoglobin Content as Predictors of Early Response to Exclusive Oral Iron in Children with Iron Deficiency Anemia. ( 27092272 )
2016
25
Prevalence and Risk Factors for Iron Deficiency Anemia and Iron Depletion During Pregnancy: A Prospective Study. ( 28060688 )
2016
26
Iron deficiency anemia and megaloblastic anemia in obese patients. ( 27648630 )
2016
27
Comparison of serum paraoxonase and arylesterase activities between iron deficiency anemia patients and chronic kidney disease patients with anemia. ( 27050633 )
2016
28
Parenteral iron therapy in children with iron deficiency anemia. ( 27175456 )
2016
29
Gastrointestinal Pyogenic Granuloma (Lobular Capillary Hemangioma): An Underrecognized Entity Causing Iron Deficiency Anemia. ( 27403353 )
2016
30
Efficacy and safety of adjuvant recombinant human erythropoietin and ferrous sulfate as treatment for iron deficiency anemia during the third trimester of pregnancy. ( 27566219 )
2016
31
Efficacy and safety of iron isomaltoside (Monofer(Ar)) in the management of patients with iron deficiency anemia. ( 27022297 )
2016
32
Embolic Stroke due to a Common Carotid Artery Thrombus in a Young Patient with Severe Iron-Deficiency Anemia without Thrombocytosis. ( 27752375 )
2016
33
Usefulness of Reticulocyte Hemoglobin Equivalent in Management of Regular Hemodialysis Patients with Iron Deficiency Anemia. ( 27141568 )
2016
34
Duodenal Amyloidosis Masquerading as Iron Deficiency Anemia. ( 27625911 )
2016
35
Association of Iron Deficiency Anemia With Hearing Loss in US Adults. ( 28033450 )
2016
36
Outcome of endoscopy-negative iron deficiency anemia in patients above 65: A longitudinal multicenter cohort. ( 27893668 )
2016
37
Response of Iron Deficiency Anemia to Intravenous Iron Sucrose in Pediatric Inflammatory Bowel Disease. ( 27199624 )
2016
38
Iron Polymaltose Complex in the Treatment of Iron Deficiency Anemia in Pregnancy. ( 27612899 )
2016
39
Peripapillary retinal nerve fiber layer thickness in patients with iron deficiency anemia. ( 27146929 )
2016
40
Dietary composition influences incidence of Helicobacter pylori-induced iron deficiency anemia and gastric ulceration. ( 27620719 )
2016
41
Serum paraoxonase 1 activity in patients with iron deficiency anemia. ( 27478448 )
2016
42
The association between subjective assessment of menstrual bleeding and measures of iron deficiency anemia in premenopausal African-American women: a cross-sectional study. ( 27524363 )
2016
43
A Rare Cause of Unexplained Refractory Iron Deficiency Anemia: Unicentric Plasma-Cell Type Castleman's Disease. ( 27102825 )
2016
44
Impact of iron deficiency anemia on the function of the immune system in children. ( 27893677 )
2016
45
A rare case of iron-deficiency anemia rapidly progressing to a life-threatening event. ( 27124228 )
2016
46
Breastfeeding, Mixed, or Formula Feeding at 9 Months of Age and the Prevalence of Iron Deficiency and Iron Deficiency Anemia in Two Cohorts of Infants in China. ( 27836288 )
2016
47
Iron deficiency anemia: like mother, like child. ( 27507308 )
2016
48
Erratum to: Renal functional and structural integrity in infants with iron deficiency anemia: relation to oxidative stress and response to iron therapy. ( 26391608 )
2016
49
Evaluation of Platelet and Red Blood Cell Parameters with Proposal of Modified Score as Discriminating Guide for Iron Deficiency Anemia and I^-Thalassemia Minor. ( 27437228 )
2016
50
Coexistence of Essential Thrombocythemia, Iron-Refractory Iron Deficiency Anemia and Renal Cell Carcinoma. ( 27103977 )
2016

Variations for Iron Deficiency Anemia

Expression for Iron Deficiency Anemia

Search GEO for disease gene expression data for Iron Deficiency Anemia.

Pathways for Iron Deficiency Anemia

GO Terms for Iron Deficiency Anemia

Cellular components related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasmic vesicle GO:0031410 9.83 HFE SLC11A2 TF TFR2 TFRC
2 cell surface GO:0009986 9.73 EPO HFE2 LTF SLC11A2 TF TFRC
3 external side of plasma membrane GO:0009897 9.71 HFE IL6 TFR2 TFRC
4 extracellular space GO:0005615 9.7 CRP EPO HAMP HFE HFE2 IL6
5 recycling endosome GO:0055037 9.62 HFE SLC11A2 TF TFRC
6 basal part of cell GO:0045178 9.33 HFE SLC11A2 TF
7 HFE-transferrin receptor complex GO:1990712 9.02 HFE HFE2 TF TFR2 TFRC
8 extracellular region GO:0005576 10.02 CRP EPO HAMP IL6 LTF TF

Biological processes related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.63 CRP EPO HAMP HFE IL6 TFR2
2 transferrin transport GO:0033572 9.62 HFE TF TFR2 TFRC
3 iron ion transport GO:0006826 9.61 SLC11A2 TF TFR2
4 multicellular organismal iron ion homeostasis GO:0060586 9.58 HAMP HFE SLC11A2
5 response to electrical stimulus GO:0051602 9.56 EPO IL6
6 response to iron ion GO:0010039 9.56 HAMP HFE SLC11A2 TFR2
7 positive regulation of receptor-mediated endocytosis GO:0048260 9.55 HFE TF
8 response to vitamin A GO:0033189 9.54 EPO HAMP
9 cellular response to iron ion GO:0071281 9.54 HFE TF TFR2
10 negative regulation of lipid storage GO:0010888 9.52 CRP IL6
11 positive regulation of peptide hormone secretion GO:0090277 9.51 HFE TFR2
12 iron ion homeostasis GO:0055072 9.5 HFE HFE2 LTF SLC11A2 TF TFR2
13 response to iron ion starvation GO:1990641 9.49 HAMP HFE
14 ferrous iron import into cell GO:0097460 9.48 TF TFR2
15 ferrous iron import across plasma membrane GO:0098707 9.46 TF TFR2
16 cellular iron ion homeostasis GO:0006879 9.23 HAMP HFE HFE2 SLC11A2 TF TFR2

Molecular functions related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 serine-type peptidase activity GO:0008236 9.54 LTF TMPRSS11A TMPRSS6
2 hormone activity GO:0005179 9.5 EPO HAMP THPO
3 glycoprotein binding GO:0001948 9.33 HFE2 TFR2 TFRC
4 co-receptor binding GO:0039706 9.26 HFE TFR2
5 transferrin receptor activity GO:0004998 8.96 TFR2 TFRC
6 transferrin receptor binding GO:1990459 8.8 HFE HFE2 TF

Sources for Iron Deficiency Anemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....