MCID: IRN001
MIFTS: 51

Iron Deficiency Anemia

Categories: Immune diseases, Blood diseases, Metabolic diseases

Aliases & Classifications for Iron Deficiency Anemia

MalaCards integrated aliases for Iron Deficiency Anemia:

Name: Iron Deficiency Anemia 12 29 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11758
ICD9CM 35 280.8
ICD10 33 D50
UMLS 69 C0029810

Summaries for Iron Deficiency Anemia

MalaCards based summary : Iron Deficiency Anemia is related to sickle cell anemia and malaria. An important gene associated with Iron Deficiency Anemia is TMPRSS6 (Transmembrane Protease, Serine 6), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and HIF-1 signaling pathway. The drugs Iron and Zinc have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and brain, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Iron-deficiency anemia is anemia caused by a lack of iron. Anemia is defined as a decrease in the number... more...

Related Diseases for Iron Deficiency Anemia

Diseases related to Iron Deficiency Anemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 198)
id Related Disease Score Top Affiliating Genes
1 sickle cell anemia 28.7 EPO HFE TF TFR2 TFRC
2 malaria 28.4 CRP EPO HAMP IL6 TFRC
3 iron-refractory iron deficiency anemia 12.5
4 microcytic anemia 11.3
5 plummer vinson syndrome 11.2
6 gastric antral vascular ectasia 11.2
7 autoimmune atrophic gastritis 11.2
8 deficiency anemia 11.1
9 iron metabolism disease 11.0
10 hiatus hernia 10.9
11 ancylostomiasis 10.9
12 dyserythropoietic anemia, congenital, type iii 10.9
13 dermatoosteolysis, kirghizian type 10.7 HFE TF
14 superior vena cava syndrome 10.6 LTF TF
15 pituicytoma 10.6 LTF TF
16 chronic inflammatory demyelinating polyneuritis 10.6 EPO THPO
17 halal setton wang syndrome 10.5 LTF TF
18 segmental odontomaxillary dysplasia 10.5 LTF TF
19 klippel-feil syndrome 4, autosomal recessive, with myopathy and facial dysmorphism 10.5 EPO HFE2 TMPRSS6
20 urethral gland abscess 10.4 CRP EPO
21 thalassemia 10.4
22 euthyroid sick syndrome 10.4 CRP TF
23 afferent loop syndrome 10.4 EPO TFRC THPO
24 slate pneumoconiosis 10.4 HFE TF TFRC
25 distal arthrogryposis 10.4 SLC11A2 TF TMPRSS6
26 cerebral sarcoidosis 10.3 EPO TF
27 posterior foramen magnum meningioma 10.3 TF TFRC
28 diarrhea 1, secretory chloride, congenital 10.3 HFE TFR2
29 microcephaly 8, primary, autosomal recessive 10.3 CRP EPO TF
30 inflammatory bowel disease 10.2
31 intramuscular hemangioma 10.2 CRP EPO TF
32 thrombocytosis 10.2
33 celiac disease 10.2
34 thalassemia minor 10.2
35 virilizing ovarian tumor 10.2 EPO IL6
36 lymphedema 10.2 HFE TF THPO
37 harp syndrome 10.2 CRP HFE TF
38 endometrial adenocarcinoma 10.1 EPO HAMP HFE TF
39 asphyxia neonatorum 10.1 EPO IL6
40 timothy syndrome type 2 10.1 EPO HFE TF TFRC
41 thrombosis 10.1
42 hemosiderosis 10.1
43 tinf2-related dyskeratosis congenita 10.1 HAMP HFE TF TFRC
44 tongue squamous cell carcinoma 10.1 EPO HFE TF TFRC
45 gastritis 10.1
46 kidney disease 10.1
47 pulmonary hemosiderosis 10.1
48 hemangioma 10.1
49 cerebritis 10.1
50 acute myeloblastic leukemia without maturation 10.1 EPO IL6

Comorbidity relations with Iron Deficiency Anemia via Phenotypic Disease Network (PDN): (show top 50) (show all 98)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Alcoholic Liver Cirrhosis Alzheimer Disease
Anxiety Disorder Aplastic Anemia
Ascending Colon Cancer Atrophic Gastritis
Benign Essential Hypertension Bronchitis
Bronchopneumonia Cecal Benign Neoplasm
Celiac Disease Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Chronic Kidney Failure Chronic Myocardial Ischemia
Chylomicron Retention Disease Colorectal Cancer
Conjunctivitis Crohn's Disease
Cystitis Decubitus Ulcer
Deficiency Anemia Dermatomycosis
Duodenitis Dysthymic Disorder
Encephalopathy Esophageal Candidiasis
Esophageal Disease Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Folic Acid Deficiency Anemia Gastrointestinal System Cancer
Generalized Atherosclerosis Gout
Heart Disease Hepatic Flexure Cancer
Hydronephrosis Hypersplenism
Hypertension, Essential Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis
Hypoglycemia Hypoglycemic Coma
Hypothyroidism Intermediate Coronary Syndrome

Graphical network of the top 20 diseases related to Iron Deficiency Anemia:



Diseases related to Iron Deficiency Anemia

Symptoms & Phenotypes for Iron Deficiency Anemia

MGI Mouse Phenotypes related to Iron Deficiency Anemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.03 THPO TMPRSS6 EPO HFE HFE2 IL6
2 homeostasis/metabolism MP:0005376 9.97 CRP EPO HFE HFE2 IL6 LTF
3 cardiovascular system MP:0005385 9.92 CRP EPO HFE2 IL6 MB SLC11A2
4 immune system MP:0005387 9.7 IL6 LTF SLC11A2 TFR2 TFRC THPO
5 liver/biliary system MP:0005370 9.28 EPO HFE HFE2 IL6 LTF SLC11A2

Drugs & Therapeutics for Iron Deficiency Anemia

Drugs for Iron Deficiency Anemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 259)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
2
Zinc Approved Phase 4,Phase 3,Early Phase 1 7440-66-6 32051 23994
3
Halofantrine Approved Phase 4 69756-53-2 37393
4
Copper Approved Phase 4,Phase 3 7440-50-8 27099
5
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 11953898 5460373 44475014
6
Selenium Approved, Vet_approved Phase 4,Phase 3 7782-49-2
7
Metronidazole Approved Phase 4 443-48-1 4173
8
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
9
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 11103-57-4, 68-26-8 445354
10
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1 50-81-7 5785 54670067
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 59-30-3 6037
12
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1 58-05-9 143 6006
13
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 6221 10883523 5280795
14
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 68-19-9 44176380
15
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3 59-67-6 938
16
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3 98-92-0 936
17
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3 66-72-8 1050
18
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 65-23-6 1054
19
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 83-88-5 493570
20
Thiamine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-43-8 1130
21 Tocopherol Approved, Nutraceutical Phase 4,Phase 3,Phase 1
22
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 1406-16-2
23
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1 59-02-9 14985
24
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
25
Iodine Investigational Phase 4,Phase 3 7553-56-2 807
26 Ferric Compounds Phase 4,Phase 3,Phase 2,Phase 1
27 Ferric oxide, saccharated Phase 4,Phase 2,Phase 3,Phase 1
28 Hematinics Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
29 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
30 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Teferrol Phase 4,Phase 3
32 Retinol palmitate Phase 4,Phase 3,Phase 2,Early Phase 1
33 Vitamins Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Ferrous gluconate Phase 4,Phase 1
35 Ferrous fumarate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Anticoagulants Phase 4,Phase 3,Phase 2,Phase 1
37 Blood Substitutes Phase 4,Phase 3,Phase 2,Phase 1
38 Dextrans Phase 4,Phase 3,Phase 2,Phase 1
39 Iron-Dextran Complex Phase 4,Phase 3,Phase 2,Phase 1
40 Plasma Substitutes Phase 4,Phase 3,Phase 2,Phase 1
41 Ferrosoferric Oxide Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
42 Parenteral Nutrition Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
44 Epoetin alfa Phase 4,Phase 2,Phase 3,Phase 1 113427-24-0
45 ferric gluconate Phase 4,Phase 2,Phase 3,Phase 1
46 Vitamin B Complex Phase 4,Phase 2,Phase 3,Phase 1
47 Hepcidins Phase 4,Phase 1,Phase 2
48 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Lactoferrin Phase 4,Phase 1,Phase 2
50 cadexomer iodine Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 499)

id Name Status NCT ID Phase Drugs
1 Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate. Unknown status NCT00199277 Phase 4 i.v. iron sucrose;Oral iron
2 Capsule Endoscopy vs Standard of Care for Obscure Intestinal Bleeding Unknown status NCT00694954 Phase 4
3 Prevention of Iron Deficiency in 2nd Year of Life Unknown status NCT00479102 Phase 4 Ferripel-3 - iron polysaccharide complex for prevention
4 Different Iron Supplements for Prevention of Anemia in Pregnancy Unknown status NCT02487719 Phase 4 Iron sulfate and Iron polymaltose for prevention of iron deficiency anemia
5 Nutrient Fortified Oat Drink Unknown status NCT01418898 Phase 4
6 Iron Deficiency In Pulmonary Hypertension Unknown status NCT01288651 Phase 4 Ferricarboxymaltose
7 Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations. Unknown status NCT00248716 Phase 4 Ferrous gluconate and iron polysaccharide complex
8 Effect Of Intravenous Iron Versus Placebo On Muscle Oxidative Capacity And Physical Performance In Non Anemic Premenopausal Women With Low Ferritin Levels Unknown status NCT01374776 Phase 4 Double blind, randomized, placebo controlled inter
9 Iron Supplementation of Marginally Low Birth Weight Infants Unknown status NCT00558454 Phase 4 Iron
10 Iron Absorption Trial Unknown status NCT02228902 Phase 4 Ferrous fumarate;Ferrous gluconate
11 Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy Completed NCT02086838 Phase 4 Theragran Hematinic;low molecular weight iron dextran
12 Prevention of Iron Deficiency in Breastfed Infants Completed NCT01444261 Phase 4
13 Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia Completed NCT01904864 Phase 4 elemental iron (NovaFerrum®);elemental iron (Ferrous Sulfate)
14 Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies Completed NCT01221844 Phase 4 FerroGrad by Abbott
15 Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy Completed NCT01245777 Phase 4 ferric carboxymaltose
16 Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin Completed NCT00802139 Phase 4 venoferrum(iron sucrose);Bolgre (Iron acetyl-transferase)
17 A Trial of Iron Replacement in Patients With Iron Deficiency. Completed NCT01067547 Phase 4 Iron Sucrose.;Iron sucrose
18 Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate Completed NCT01991314 Phase 4 Ferrous sulphate
19 Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients Completed NCT01942460 Phase 4 Ferumoxytol
20 A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency Completed NCT01453608 Phase 4 Ferinject (ferric carboxymaltose);Placebo (saline)
21 Iron Indices and Intravenous Ferumoxytol: Time to Steady State Completed NCT01148745 Phase 4 ferumoxytol
22 Study of the Efficacy of Two Doses of Ferrlecit in the Treatment of Iron Deficiency in Pediatric Hemodialysis Patients Completed NCT00223964 Phase 4 Ferrlecit (sodium ferric gluconate complex in sucrose injection)
23 Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure Completed NCT01922479 Phase 4 Ferric Carboxymaltose;Placebo
24 Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron. Completed NCT02392910 Phase 4 Iron Sucrose;Placebo
25 Endovenous Versus Liposomal Iron in CKD Completed NCT01864161 Phase 4 gluconate iron;Liposomal iron
26 Iron Substitution in Blood Donors Completed NCT01519830 Phase 4 Iron carboxymaltose (Ferinject);Placebo
27 Short-Term Effects & Safety of an Accelerated Intravenous Iron Regimen in Patients With Heart Failure Completed NCT01925703 Phase 4 Sodium ferric gluconate
28 Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment Completed NCT00746551 Phase 4 Ferli-6® (Continental Pharm co., ltd.);Venofer® (Vifor AG, St. Gallen, Switzerland)
29 Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age Completed NCT01110356 Phase 4 Ferinject
30 Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya Completed NCT01088958 Phase 4
31 Effectiveness of Adaptation of the Dose of Iron Supplementation in Pregnancy on Maternal-child Health. (ECLIPSES) Completed NCT03196882 Phase 4 40mg/day of iron;20mg/day of iron;80mg/day of iron
32 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Completed NCT00224055 Phase 4 Sodium Ferric Gluconate Complex in Sucrose Injection;Ferrous sulfate tablets
33 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents Completed NCT00224042 Phase 4 Sodium Ferric Gluconate complex in sucrose;Ferrous sulfate tablets
34 Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors Completed NCT00689793 Phase 4 Ferrous sulphate;Placebo
35 DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin) Completed NCT00224081 Phase 4 Sodium ferric gluconate,
36 Switch From Oral Iron to Intravenous Ferric Carboxymaltose in Non-dialysis Chronic Kidney Disease (CKD) Completed NCT02232906 Phase 4 intravenous ferric carboxymaltose
37 Effect of Two Iron Preparations on Protein in the Urine Completed NCT00354692 Phase 4 Sodium Ferric Gluconate and Iron sucrose
38 Efficacy of Intravenous Iron Administration in Hemodialysis Patients Completed NCT00298441 Phase 4 chondroitin sulfate-iron colloid
39 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
40 Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study) Completed NCT01609387 Phase 4
41 Periodic Versus Continuous IV Iron Supplementation in HD Patients Completed NCT02787824 Phase 4 Iron Sucrose Supplement
42 The Use of Liposomated Iron After Bariatric Surgery in Patients That Are Receiving Parentheral Therapy With Iron Completed NCT02390921 Phase 4 Fisiogen Ferro Forte;Venofer
43 Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination Completed NCT00677794 Phase 4 Clear fluids;Picosalax;Polyethylene glycol
44 Effect of Iron Therapy as an Adjunct to Epoetin Alfa in the Anemia of Cancer Chemotherapy Completed NCT00224068 Phase 4 Sodium ferric gluconate, ferrous sulfate, standard of care
45 Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD Recruiting NCT02774057 Phase 4 Captafer®;Iron Sulfate
46 Iron Treatment for Young Children With Non-anemic Iron Deficiency Recruiting NCT01481766 Phase 4
47 Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome. Recruiting NCT02031289 Phase 4 Erythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
48 Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy Recruiting NCT03202615 Phase 4 F (ferrous sulphate)
49 the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients Recruiting NCT02631668 Phase 4 ferrous succinate and vitamin C;ferrous succinate;ferrous succinate
50 KRX-0502 (Ferric Citrate) in Subjects With NDD-CKD and IDA (The COMPASS Trial) Recruiting NCT03236246 Phase 4 KRX-0502

Search NIH Clinical Center for Iron Deficiency Anemia

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Iron Deficiency Anemia

Genetic tests related to Iron Deficiency Anemia:

id Genetic test Affiliating Genes
1 Iron Deficiency Anemia 29

Anatomical Context for Iron Deficiency Anemia

MalaCards organs/tissues related to Iron Deficiency Anemia:

39
Heart, Kidney, Brain, Testes, Breast, Skeletal Muscle, Bone

Publications for Iron Deficiency Anemia

Articles related to Iron Deficiency Anemia:

(show top 50) (show all 766)
id Title Authors Year
1
A budget impact analysis of parenteral iron treatments for iron deficiency anemia in the UK: reduced resource utilization with iron isomaltoside 1000. ( 28848355 )
2017
2
A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. ( 28052413 )
2017
3
Curative resectability of gastrointestinal cancer identified from iron deficiency anemia. ( 28943943 )
2017
4
Ability of serum ferritin to diagnose iron deficiency anemia in an elderly cohort. ( 28830601 )
2017
5
Effects of Ferric Citrate in Patients with Nondialysis-Dependent CKD and Iron Deficiency Anemia. ( 28082519 )
2017
6
Enhanced nickel sensitivity in iron deficiency anemia. ( 28928308 )
2017
7
Preoperative management of colorectal cancer-induced iron deficiency anemia in clinical practice: data from a large observational cohort. ( 28833205 )
2017
8
Delusional parasitosis secondary to severe iron deficiency anemia. ( 28879221 )
2017
9
Correction to: Carvalho et al., Prevalence of iron deficiency anemia and iron deficiency in a pediatric population with inflammatory bowel disease. ( 28853335 )
2017
10
Helicobacter pylori sabA gene is associated with iron deficiency anemia in childhood and adolescence. ( 28854239 )
2017
11
Comparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemia. ( 28872486 )
2017
12
Idiopathic Pulmonary Hemosiderosis Mimicking Iron Deficiency Anemia: A Delayed Diagnosis? ( 28670434 )
2017
13
Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child. ( 28460265 )
2017
14
Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study. ( 28073037 )
2017
15
Author's reply: Directly observed iron supplementation for control of iron deficiency anemia. ( 28928309 )
2017
16
Reply: Intravenous Ferumoxytol in Pediatric Patients With Iron-Deficiency Anemia. ( 28831808 )
2017
17
New Bioinformatics-Based Discrimination Formulas for Differentiation of Thalassemia Traits From Iron Deficiency Anemia. ( 28934514 )
2017
18
Primary care physicians are under-testing for celiac disease in patients with iron deficiency anemia: Results of a national survey. ( 28931034 )
2017
19
Total dose iron dextran infusion versus oral iron for treating iron deficiency anemia in pregnant women: a randomized controlled trial. ( 28901214 )
2017
20
Comment: Intravenous Ferumoxytol in Pediatric Patients With Iron Deficiency Anemia. ( 28925297 )
2017
21
Iron Refractory Iron Deficiency Anemia in Dizygotic Twins Due to a Novel TMPRSS6 Gene Mutation in Addition to Polymorphisms Associated With High Susceptibility to Develop Ferropenic Anemia. ( 28491880 )
2017
22
Challenges in the diagnosis of iron deficiency anemia in aged people. ( 28830594 )
2017
23
Assessment of the Matos & Carvalho index for distinguishing thalassemia from iron deficiency anemia. ( 28830614 )
2017
24
Phase III randomized trial comparing intravenous to oral iron in patients with cancer-related iron deficiency anemia not on erythropoiesis stimulating agents. ( 28849623 )
2017
25
Prevalence of Iron Deficiency and Iron Deficiency Anemia in the Northern and Southern Provinces of Rwanda. ( 28826251 )
2017
26
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population. ( 28492865 )
2017
27
Ferric carboxymaltose reduces the number of red blood cell units transfused and allows transfusion independence to be obtained in patients with iron deficiency anemia secondary to gastrointestinal chronic blood loss. ( 27600706 )
2016
28
Gastroduodenal lesions in iron-deficiency anemia. ( 27852537 )
2016
29
Impact of iron deficiency anemia on the function of the immune system in children. ( 27893677 )
2016
30
Pediatric Crohn's disease, iron deficiency anemia and intravenous iron treatment: a follow-up study. ( 27576956 )
2016
31
A Curious Case of Iron-Deficiency Anemia. ( 27446874 )
2016
32
Cost-Effectiveness of Price Subsidies on Fortified Packaged Infant Cereals in Reducing Iron Deficiency Anemia in 6-23-Month-Old-Children in Urban India. ( 27073892 )
2016
33
Absolute Reticulocyte Count and Reticulocyte Hemoglobin Content as Predictors of Early Response to Exclusive Oral Iron in Children with Iron Deficiency Anemia. ( 27092272 )
2016
34
Coexistence of Essential Thrombocythemia, Iron-Refractory Iron Deficiency Anemia and Renal Cell Carcinoma. ( 27103977 )
2016
35
A new index to discriminate between iron deficiency anemia and thalassemia trait. ( 27521859 )
2016
36
A 5-Year Follow-Up of Study Patients With Asymptomatic Iron-Deficiency Anemia Using a Nurse-Led Pathway. ( 27922517 )
2016
37
Severe childhood caries associated with iron deficiency anemia: a case report. ( 27148650 )
2016
38
The association between subjective assessment of menstrual bleeding and measures of iron deficiency anemia in premenopausal African-American women: a cross-sectional study. ( 27524363 )
2016
39
Usefulness of Reticulocyte Hemoglobin Equivalent in Management of Regular Hemodialysis Patients with Iron Deficiency Anemia. ( 27141568 )
2016
40
Hemodynamic response to treatment of iron deficiency anemia in pulmonary arterial hypertension: longitudinal insights from an implantable hemodynamic monitor. ( 28090307 )
2016
41
Breastfeeding, Mixed, or Formula Feeding at 9 Months of Age and the Prevalence of Iron Deficiency and Iron Deficiency Anemia in Two Cohorts of Infants in China. ( 27836288 )
2016
42
Prevalence of Thalassemia Trait & Iron Deficiency Anemia during Infancy in 2011-2013 in a Thalassemia Prevalent Region: North Cyprus. ( 27928530 )
2016
43
Prevalence and Risk Factors for Iron Deficiency Anemia and Iron Depletion During Pregnancy: A Prospective Study. ( 28060688 )
2016
44
Response to parenteral iron therapy distinguish unexplained refractory iron deficiency anemia from iron-refractory iron deficiency anemia. ( 26818204 )
2016
45
Iron deficiency anemia in infants and toddlers. ( 28090490 )
2016
46
A rare case of iron-deficiency anemia rapidly progressing to a life-threatening event. ( 27124228 )
2016
47
Iron Refractory Iron Deficiency Anemia (IRIDA): A heterogeneous disease that is not always iron refractory. ( 27643674 )
2016
48
Iron-refractory iron deficiency anemia (IRIDA) cases with 2 novel TMPRSS6 mutations. ( 27120435 )
2016
49
A Rare Cause of Unexplained Refractory Iron Deficiency Anemia: Unicentric Plasma-Cell Type Castleman's Disease. ( 27102825 )
2016
50
Iron deficiency anemia in the emergency department: over-utilization of red blood cell transfusion and infrequent use of iron supplementation. ( 27819205 )
2016

Variations for Iron Deficiency Anemia

Expression for Iron Deficiency Anemia

Search GEO for disease gene expression data for Iron Deficiency Anemia.

Pathways for Iron Deficiency Anemia

GO Terms for Iron Deficiency Anemia

Cellular components related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasmic vesicle GO:0031410 9.83 HFE SLC11A2 TF TFR2 TFRC
2 cell surface GO:0009986 9.73 EPO HFE2 LTF SLC11A2 TF TFRC
3 extracellular space GO:0005615 9.7 CRP EPO HAMP HFE HFE2 IL6
4 external side of plasma membrane GO:0009897 9.67 HFE IL6 TFR2 TFRC
5 recycling endosome GO:0055037 9.62 HFE SLC11A2 TF TFRC
6 basal part of cell GO:0045178 9.33 HFE SLC11A2 TF
7 HFE-transferrin receptor complex GO:1990712 9.02 HFE HFE2 TF TFR2 TFRC
8 extracellular region GO:0005576 10.01 CRP EPO HAMP IL6 LTF TF

Biological processes related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.63 CRP EPO HAMP HFE IL6 TFR2
2 transferrin transport GO:0033572 9.62 HFE TF TFR2 TFRC
3 iron ion transport GO:0006826 9.61 SLC11A2 TF TFR2
4 multicellular organismal iron ion homeostasis GO:0060586 9.58 HAMP HFE SLC11A2
5 response to iron ion GO:0010039 9.56 HAMP HFE SLC11A2 TFR2
6 positive regulation of receptor-mediated endocytosis GO:0048260 9.54 HFE TF
7 cellular response to iron ion GO:0071281 9.54 HFE TF TFR2
8 response to vitamin A GO:0033189 9.52 EPO HAMP
9 negative regulation of lipid storage GO:0010888 9.51 CRP IL6
10 iron ion homeostasis GO:0055072 9.5 HFE HFE2 LTF SLC11A2 TF TFR2
11 positive regulation of peptide hormone secretion GO:0090277 9.49 HFE TFR2
12 response to iron ion starvation GO:1990641 9.48 HAMP HFE
13 ferrous iron import across plasma membrane GO:0098707 9.46 TF TFR2
14 cellular iron ion homeostasis GO:0006879 9.23 HAMP HFE HFE2 SLC11A2 TF TFR2

Molecular functions related to Iron Deficiency Anemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.43 EPO HAMP THPO
2 co-receptor binding GO:0039706 9.16 HFE TFR2
3 transferrin receptor activity GO:0004998 8.96 TFR2 TFRC
4 transferrin receptor binding GO:1990459 8.8 HFE HFE2 TF

Sources for Iron Deficiency Anemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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