MCID: IRR003
MIFTS: 40

Irritant Dermatitis malady

Skin diseases category

Summaries for Irritant Dermatitis

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Contact dermatitis is a type of skin inflammation (dermatitis). more...

MalaCards: Irritant Dermatitis, also known as primary irritant dermatitis, is related to dermatitis and contact dermatitis. An important gene associated with Irritant Dermatitis is LCE5A (late cornified envelope 5A). The compounds calcipotriol and sodium dodecylsulfate have been mentioned in the context of this disorder. Affiliated tissues include skin and testes.

Aliases & Classifications for Irritant Dermatitis

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 26ICD10
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Related Diseases for Irritant Dermatitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Irritant Dermatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1dermatitis31.4KRT16, LOR, IL1A
2contact dermatitis30.5KRT16, IL1A
3skin disease30.5IL1A, LOR, KRT16
4psoriasis30.2IL1A, LOR, KRT16
5atopic dermatitis30.1LOR, IL1A
6erythema multiforme10.4
7atopy10.4
8diaper rash10.2
9erysipelas10.2
10tinea manuum10.2
11alopecia10.2
12conjunctivitis10.2
13lymphedema10.2
14alopecia totalis10.2
15toxic epidermal necrolysis10.2
16allergic contact dermatitis10.2
17burns10.1
18basal cell carcinoma10.1
19scabies10.1
20keratoderma10.0KRT16, LOR
21palmoplantar keratosis10.0KRT16, LOR
22epidermolytic hyperkeratosis10.0LOR, KRT16
23nonepidermolytic palmoplantar keratoderma10.0LOR, KRT16
24keratosis10.0LOR, KRT16
25cholesteatoma10.0KRT16, IL1A

Graphical network of the top 20 diseases related to Irritant Dermatitis:



Diseases related to irritant dermatitis

Symptoms for Irritant Dermatitis

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Drugs & Therapeutics for Irritant Dermatitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Irritant Dermatitis

Drug clinical trials:

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Search NIH Clinical Center for Irritant Dermatitis

Search CenterWatch for Irritant Dermatitis

Genetic Tests for Irritant Dermatitis

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Anatomical Context for Irritant Dermatitis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Irritant Dermatitis:

34
Skin, Testes

Animal Models for Irritant Dermatitis or affiliated genes

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Publications for Irritant Dermatitis

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53PubMed
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Articles related to Irritant Dermatitis:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
IL-6 deficiency exacerbates skin inflammation in a murine model of irritant dermatitis. (22966985)
2013
2
To evaluate the efficacy and safety of "RV2427B" cream in Irritant dermatitis care. (23984228)
2013
3
Allergic and irritant dermatitis: pathogenic and management aspects. (22827836)
2012
4
Contact irritant dermatitis in Kenya. (23472569)
2012
5
Hand hygiene compliance and irritant dermatitis: a juxtaposition of healthcare issues. (22691060)
2012
6
IL-6, VEGF, KC and RANTES are a major cause of a high irritant dermatitis to phthalic anhydride in C57BL/6 inbred mice. (20864798)
2010
7
Povidone iodine irritant dermatitis. (20606840)
2010
8
WOC nurse consult: Moist, painful peristomal skin. Chemical irritant dermatitis and pseudoverrucous lesions. (20228658)
2010
9
Hair highlights and severe acute irritant dermatitis ("burn") of the scalp. (20854194)
2010
10
Contact irritant dermatitis from insect secretions: report of 74 cases in a military unit in Eritrea. (19731793)
2009
11
Treatment with pimecrolimus cream 1% clears irritant dermatitis of the periocular region, face and neck. (18937664)
2008
12
The effect of irritant dermatitis on cutaneous bioavailability of a metronidazole formulation, investigated by microdialysis and dermatopharmacokinetic method. (18537995)
2008
13
Occlusive irritant dermatitis: when is "allergic" contact dermatitis not allergic? (17366682)
2007
14
Contact and primary irritant dermatitis of the nail unit diagnosis and treatment. (17403259)
2007
15
Moisturizer effect on irritant dermatitis: an overview. (16930228)
2006
16
Effectiveness of a hand care regimen with moisturizer in manufacturing facilities where workers are prone to occupational irritant dermatitis. (15573643)
2004
17
Irritant dermatitis to detergents in textiles. (12882025)
2003
18
Successfully managing incontinence-related irritant dermatitis across the lifespan. (10347509)
1999
19
Crystal deodorant dermatitis: irritant dermatitis to alum-containing deodorant. (10431678)
1999
20
Arachidonic acid metabolism in primary irritant dermatitis produced by patch testing of human skin with surfactants. (9875300)
1998
21
What's new in irritant dermatitis. (9255463)
1997
22
Predictive testing in contact dermatitis. Irritant dermatitis. (9255475)
1997
23
Pigmented and hyperkeratotic napkin dermatitis: a liquid detergent irritant dermatitis. (8864616)
1996
24
Irritant dermatitis: experimental aspects. (9035907)
1995
25
Acute irritant dermatitis: effect of short-term topical corticoid treatment. (7587340)
1995
26
Sodium hydroxide-induced irritant dermatitis as assessed by computerized elaboration of 20 MHz B-scan images and by TEWL measurement: a method for investigating skin barrier function. (7604663)
1995
27
The causes of irritant dermatitis. (8240913)
1993
28
Moisturizers prevent irritant dermatitis. (1350143)
1992
29
Susceptibility of atopic dermatitis patients to irritant dermatitis caused by sodium lauryl sulphate. (1681644)
1991
30
Increased stratum corneum turnover induced by subclinical irritant dermatitis. (2369560)
1990
31
Susceptibility to irritant dermatitis induced by sodium lauryl sulfate. (2365862)
1990
32
Cumulative irritant dermatitis and abnormal epidermal plasminogen activator activity: what connection? (2531125)
1989
33
Susceptibility to cumulative and acute irritant dermatitis. An experimental approach in human volunteers. (3180788)
1988
34
Irritant dermatitis from tetrachloroisophthalonitrile. (3720299)
1986
35
Prevention of irritant dermatitis. (2956714)
1986
36
Vulvar dermatitis and fissures--irritant dermatitis from methyl benzethonium chloride. (2936553)
1985
37
Irritant dermatitis due to Euphorbia marginata. (4042646)
1985
38
Severe irritant dermatitis mimicking a basal cell carcinoma. (6230178)
1983
39
Dermal glycosaminoglycans characterise the primary irritant dermatitis in psoriatics and healthy individuals. (6409454)
1983
40
Suppression of DNCB-induced irritant dermatitis by colchicine. (6173985)
1981
41
Prostaglandin E1 in suction-separated human epidermal tissue in primary irritant dermatitis. (6172932)
1981
42
Irritant dermatitis from phenol-formaldehyde resin powder. (6452249)
1980
43
Primary irritant dermatitis from topical clioquinol. (157250)
1979
44
Irritant dermatitis during the relining of a blast furnace. (141356)
1977
45
Temperature dependent primary irritant dermatitis from lemon perfume. (139284)
1977
46
Irritant dermatitis from diallylglycol carbonate monomer in the optical industry: clinical and experimental studies of cutaneous tolerance and chemical investigations. (139275)
1976
47
Contact allergic and primary irritant dermatitis in industry vs. what else? (4274012)
1974
48
3H-thymidine incorporation into circulating white cells during allergic and irritant dermatitis in guinea pigs. (4855450)
1974
49
Recovery of prostaglandins in human primary irritant dermatitis. (4415499)
1974
50
Primary irritant dermatitis of the scrotum due to hexachlorophene. (4239294)
1969

Variations for Irritant Dermatitis

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Expression for genes affiliated with Irritant Dermatitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Irritant Dermatitis

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Pathways for genes affiliated with Irritant Dermatitis

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Compounds for genes affiliated with Irritant Dermatitis

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 12DrugBank, 25HMDB
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Compounds related to Irritant Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcipotriol46 62 30 1212.4IL1A, KRT16
2sodium dodecylsulfate469.4IL1A, KRT16
31,25 dihydroxy vitamin d3469.3IL1A, KRT16
4calcitriol46 62 25 1212.0KRT16, IL1A
5vitamin a46 25 1211.0LOR, IL1A, KRT16
6serine468.9KRT16, IL1A, LOR
7retinoic acid46 259.8KRT16, IL1A, LOR

GO Terms for genes affiliated with Irritant Dermatitis

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Sources:
17Gene Ontology
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Biological processes related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell proliferationGO:0082839.3KRT16, IL1A
2epidermis developmentGO:0085449.1KRT16, LCE2B
3keratinizationGO:0314248.2LCE3A, LCE5A, LCE2B, LOR

Molecular functions related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.5KRT16, LOR

Products for genes affiliated with Irritant Dermatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Irritant Dermatitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet