MCID: IRR003
MIFTS: 32

Irritant Dermatitis malady

Skin category

Summaries for Irritant Dermatitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Contact dermatitis is a type of skin inflammation (dermatitis) that results from exposure to allergens... more...

MalaCards: Irritant Dermatitis, also known as primary irritant dermatitis, is related to atopic dermatitis and erythema multiforme. An important gene associated with Irritant Dermatitis is LCE5A (late cornified envelope 5A). The compounds calcipotriol and 1,25 dihydroxy vitamin d3 have been mentioned in the context of this disorder.

Aliases & Classifications for Irritant Dermatitis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH, 25ICD10
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Related Diseases for Irritant Dermatitis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Irritant Dermatitis:



Diseases related to irritant dermatitis

Clinical Features for Irritant Dermatitis

Drugs & Therapeutics for Irritant Dermatitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Irritant Dermatitis

Drug clinical trials:

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Search NIH Clinical Center for Irritant Dermatitis

Search CenterWatch for Irritant Dermatitis

Genetic Tests for Irritant Dermatitis

Anatomical Context for Irritant Dermatitis

Animal Models for Irritant Dermatitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Irritant Dermatitis

Sources:
51PubMed
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Articles related to Irritant Dermatitis:

(show top 50)    (show all 140)
idTitleAuthorsYear
1
Contact dermatitis: Allergic and irritant. (24314385)
2014
2
Posttraumatic irritant contact dermatitis - an underdiagnosed entity? (24119194)
2013
3
Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis. (23039796)
2013
4
Irritant contact dermatitis to accidental exposure of cyanide. (23716845)
2013
5
To evaluate the efficacy and safety of "RV2427B" cream in Irritant dermatitis care. (23984228)
2013
6
Acute irritant threshold correlates with barrier function, skin hydration and contact hypersensitivity in atopic dermatitis and rosacea. (24112695)
2013
7
P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis. (23489421)
2013
8
Clinical course of occupational irritant contact dermatitis of the hands in relation to filaggrin genotype status and atopy. (22962861)
2012
9
Management of irritant contact dermatitis and peripherally inserted central catheters. (22459537)
2012
10
Oral administration of glucosylceramide ameliorates inflammatory dry-skin condition in chronic oxazolone-induced irritant contact dermatitis in the mouse ear. (22726258)
2012
11
Occupational irritant contact dermatitis caused by Lobelia richardii in an Ethiopian flower farm. (22775548)
2012
12
Irritant contact dermatitis due to the use of a continuous positive airway pressure nasal mask: 2 case reports and review of the literature. (23094310)
2012
13
Contact dermatitis caused by chlorothalonil on imported roses: irritant or allergic reaction? (21658059)
2011
14
The effect of damaged skin barrier induced by subclinical irritation on the sequential irritant contact dermatitis. (21774626)
2011
15
Use of frozen poloxamer as a base for Itchy skin conditions, including irritant contact dermatitis. (21781082)
2011
16
Contact depigmentation following irritant contact dermatitis to chloroxylenol (Dettol). (21860168)
2011
17
IL-6, VEGF, KC and RANTES are a major cause of a high irritant dermatitis to phthalic anhydride in C57BL/6 inbred mice. (20864798)
2010
18
Povidone iodine irritant dermatitis. (20606840)
2010
19
Moisturizer effect on irritant dermatitis: an overview. (16930228)
2006
20
Ratio of irritant contact dermatitis to allergic contact dermatitis in occupational skin disease. (12894103)
2003
21
Irritant dermatitis, irritancy and its role in allergic contact dermatitis. (11952708)
2002
22
Sea water or its components alter experimental irritant dermatitis in man. (11301639)
2001
23
An immunohistochemical analysis of cytokine expression in allergic and irritant contact dermatitis. (10954204)
2000
24
Lymphedema of the hand following recurrent erysipelas secondary to fissured irritant contact dermatitis. (10871118)
2000
25
A histological and immunohistochemical study on chronic irritant contact dermatitis. (9471983)
1998
26
Cytokines and irritant contact dermatitis. (10022266)
1998
27
Human barrier recovery after acute acetone perturbation: an irritant dermatitis model. (9667101)
1998
28
Predictive testing in contact dermatitis. Irritant dermatitis. (9255475)
1997
29
Acute irritant dermatitis: effect of short-term topical corticoid treatment. (7587340)
1995
30
Occupational dermatitis in hairdressing apprentices. Early-onset irritant skin damage. (9035926)
1995
31
Effect of N-acetylcysteine, an inhibitor of tumor necrosis factor, on irritant contact dermatitis in the human. (9035915)
1995
32
Irritant dermatitis among workers cleaning up a pesticide spill: California 1991. (7793424)
1995
33
Irritant dermatitis in the workplace. (7923942)
1994
34
The causes of irritant dermatitis. (8240913)
1993
35
Moisturizers prevent irritant dermatitis. (1350143)
1992
36
Susceptibility of atopic dermatitis patients to irritant dermatitis caused by sodium lauryl sulphate. (1681644)
1991
37
Neuropeptides enhance irritant and allergic contact dermatitis. (1708795)
1991
38
Increased stratum corneum turnover induced by subclinical irritant dermatitis. (2369560)
1990
39
Susceptibility to irritant dermatitis induced by sodium lauryl sulfate. (2365862)
1990
40
Pustular irritant dermatitis due to croton oil. Evaluation of the role played by leukocytes and complement. (2455422)
1988
41
Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol. (2960483)
1987
42
Prevention of irritant dermatitis. (2956714)
1986
43
Vulvar dermatitis and fissures--irritant dermatitis from methyl benzethonium chloride. (2936553)
1985
44
Irritant dermatitis due to Euphorbia marginata. (4042646)
1985
45
Dermal glycosaminoglycans characterise the primary irritant dermatitis in psoriatics and healthy individuals. (6409454)
1983
46
Suppression of DNCB-induced irritant dermatitis by colchicine. (6173985)
1981
47
Irritant dermatitis during the relining of a blast furnace. (141356)
1977
48
Irritant dermatitis from diallylglycol carbonate monomer in the optical industry: clinical and experimental studies of cutaneous tolerance and chemical investigations. (139275)
1976
49
Contact allergic and primary irritant dermatitis in industry vs. what else? (4274012)
1974
50
Primary irritant dermatitis from the Manchineel tree (Hippomane mancineltal inthe Eastern Caribbean. (4461811)
1974

Genetic Variations for Irritant Dermatitis

Expression for genes affiliated with Irritant Dermatitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Irritant Dermatitis

Search GEO for disease gene expression data for Irritant Dermatitis.

Pathways for genes affiliated with Irritant Dermatitis

Compounds for genes affiliated with Irritant Dermatitis

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Irritant Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcipotriol45 60 29 1112.7KRT16, IL1A
21,25 dihydroxy vitamin d3459.7KRT16, IL1A
3sodium dodecylsulfate459.4KRT16, IL1A
4vitamin a45 11 2411.2KRT16, IL1A, LOR

GO Terms for genes affiliated with Irritant Dermatitis

Sources:
16Gene Ontology
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Biological processes related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1epidermis developmentGO:0085449.5KRT16, LCE2B
2keratinizationGO:0314247.9HRNR, LCE2B, LCE5A, LCE3A, LOR

Molecular functions related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.8KRT16, LOR

Products for genes affiliated with Irritant Dermatitis

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Sources for Irritant Dermatitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet