MCID: IRR003
MIFTS: 40

Irritant Dermatitis malady

Skin diseases category

Summaries for Irritant Dermatitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Contact dermatitis is a type of skin inflammation (dermatitis) that results from exposure to allergens... more...

MalaCards: Irritant Dermatitis, also known as primary irritant dermatitis, is related to dermatitis and contact dermatitis. An important gene associated with Irritant Dermatitis is LCE5A (late cornified envelope 5A). The compounds calcipotriol and 1,25 dihydroxy vitamin d3 have been mentioned in the context of this disorder. Affiliated tissues include skin and testes.

Aliases & Classifications for Irritant Dermatitis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Related Diseases for Irritant Dermatitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Irritant Dermatitis:



Diseases related to irritant dermatitis

Clinical Features for Irritant Dermatitis

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Drugs & Therapeutics for Irritant Dermatitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Irritant Dermatitis

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Genetic Tests for Irritant Dermatitis

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Anatomical Context for Irritant Dermatitis

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32MalaCards
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MalaCards organs/tissues related to Irritant Dermatitis:

32
Skin, Testes

Animal Models for Irritant Dermatitis or affiliated genes

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Publications for Irritant Dermatitis

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50PubMed
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Articles related to Irritant Dermatitis:

(show top 50)    (show all 141)
idTitleAuthorsYear
1
Irritant contact dermatitis from a black henna tattoo without sensitization to para-phenylendiamine. (23690526)
2013
2
Facial contact dermatitis and the irritant potential of mobile phone screens. (23025548)
2013
3
Irritant contact dermatitis due to ammonium bifluoride in two infant twins. (22211467)
2013
4
Is dermatitis palmaris sicca an irritant contact dermatitis? (23665830)
2013
5
Cytokines and Chemokines in Irritant Contact Dermatitis. (24371376)
2013
6
Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis. (23039796)
2013
7
To evaluate the efficacy and safety of "RV2427B" cream in Irritant dermatitis care. (23984228)
2013
8
Chemicals inducing acute irritant contact dermatitis mobilize intracellular calcium in human keratinocytes. (22906572)
2013
9
Do-it-yourself cement work: the main cause of severe irritant contact dermatitis requiring hospitalization. (22900492)
2013
10
Allergic and irritant dermatitis: pathogenic and management aspects. (22827836)
2012
11
Irritant contact dermatitis: effect of age. (21967594)
2012
12
Contact irritant dermatitis in Kenya. (23472569)
2012
13
Fiddler's neck: Chin rest-associated irritant contact dermatitis and allergic contact dermatitis in a violin player. (23031377)
2012
14
Anti-irritants agents for the treatment of irritant contact dermatitis: clinical and patent perspective. (22827755)
2012
15
Oxidative stress in allergic and irritant dermatitis: from basic research to clinical management. (22827837)
2012
16
Allergic or irritant contact dermatitis after patch testing with alcohol--that is the point. (23151199)
2012
17
Use of frozen poloxamer as a base for Itchy skin conditions, including irritant contact dermatitis. (21781082)
2011
18
Erythema multiforme-like irritant contact dermatitis after application of an antiscabies treatment. (21658333)
2011
19
Atopic dermatitis and ichthyosis vulgaris caused by irritants in a professional windsurfer. (21569747)
2011
20
Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis. (19818069)
2010
21
Hair highlights and severe acute irritant dermatitis ("burn") of the scalp. (20854194)
2010
22
Influence of tumour necrosis factor-I+ polymorphism-308 and atopy on irritant contact dermatitis in healthcare workers. (20731689)
2010
23
Recurrent cyclic hyperkeratotic eczema after occupational alkali burn: traumatic chronic irritant dermatitis. (19489972)
2009
24
Filaggrin mutations may confer susceptibility to chronic hand eczema characterized by combined allergic and irritant contact dermatitis. (19538184)
2009
25
Treatment with pimecrolimus cream 1% clears irritant dermatitis of the periocular region, face and neck. (18937664)
2008
26
Polymorphisms in the interleukin-1 gene influence the stratum corneum interleukin-1 alpha concentration in uninvolved skin of patients with chronic irritant contact dermatitis. (18416755)
2008
27
Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis. (18416756)
2008
28
The effect of irritant dermatitis on cutaneous bioavailability of a metronidazole formulation, investigated by microdialysis and dermatopharmacokinetic method. (18537995)
2008
29
Occlusive irritant dermatitis: when is "allergic" contact dermatitis not allergic? (17366682)
2007
30
Contact and primary irritant dermatitis of the nail unit diagnosis and treatment. (17403259)
2007
31
Airborne irritant contact dermatitis and conjunctivitis after occupational exposure to chlorothalonil in textiles. (17680869)
2007
32
Irritant contact dermatitis from exposure to povidone-iodine may resemble toxic epidermal necrolysis. (17459298)
2006
33
Effectiveness of a hand care regimen with moisturizer in manufacturing facilities where workers are prone to occupational irritant dermatitis. (15573643)
2004
34
Contact irritant dermatitis and anti-pruritic agents: the need to address the itch. (12852365)
2003
35
Irritant dermatitis due to prolonged contact with Oilatum Plus. (12534617)
2003
36
Importance of irritant contact dermatitis in occupational skin disease. (12010073)
2002
37
Successfully managing incontinence-related irritant dermatitis across the lifespan. (10347509)
1999
38
Crystal deodorant dermatitis: irritant dermatitis to alum-containing deodorant. (10431678)
1999
39
Human skin lymph derived from irritant and allergic contact dermatitis: interleukin 10 is increased selectively in elicitation reactions. (9187837)
1997
40
Pigmented and hyperkeratotic napkin dermatitis: a liquid detergent irritant dermatitis. (8864616)
1996
41
Sodium hydroxide-induced irritant dermatitis as assessed by computerized elaboration of 20 MHz B-scan images and by TEWL measurement: a method for investigating skin barrier function. (7604663)
1995
42
In vivo cytokine profiles in allergic and irritant contact dermatitis. (8654078)
1995
43
Immunocytochemical detection of the carbohydrate antigen, Sialyl Lewis(x), in normal human skin and during irritant contact dermatitis. (7533625)
1994
44
Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel. (2713259)
1989
45
Disuse contractures in a patient with tinea manuum and irritant contact dermatitis. (3160548)
1985
46
Sudden onset irritant dermatitis in a car component factory. (3159932)
1985
47
Irritant dermatitis from phenol-formaldehyde resin powder. (6452249)
1980
48
Primary irritant dermatitis from topical clioquinol. (157250)
1979
49
Temperature dependent primary irritant dermatitis from lemon perfume. (139284)
1977
50
Some theoretical aspects of "orthoergic" (irritant) dermatitis. (4728171)
1973

Genetic Variations for Irritant Dermatitis

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Expression for genes affiliated with Irritant Dermatitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Irritant Dermatitis

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Pathways for genes affiliated with Irritant Dermatitis

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Compounds for genes affiliated with Irritant Dermatitis

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Sources:
44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Irritant Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcipotriol44 59 28 1112.7KRT16, IL1A
21,25 dihydroxy vitamin d3449.7KRT16, IL1A
3sodium dodecylsulfate449.4KRT16, IL1A
4vitamin a44 11 2411.2KRT16, IL1A, LOR

GO Terms for genes affiliated with Irritant Dermatitis

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16Gene Ontology
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Biological processes related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1epidermis developmentGO:0085449.5KRT16, LCE2B
2keratinizationGO:0314247.9HRNR, LCE2B, LCE5A, LCE3A, LOR

Molecular functions related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.8KRT16, LOR

Products for genes affiliated with Irritant Dermatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Irritant Dermatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet