MCID: IRR003
MIFTS: 40

Irritant Dermatitis malady

Skin diseases category

Summaries for Irritant Dermatitis

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Sources:
63Wikipedia, 32MalaCards
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Wikipedia:63 Contact dermatitis is a type of skin inflammation (dermatitis) that results from exposure to allergens... more...

MalaCards: Irritant Dermatitis, also known as primary irritant dermatitis, is related to dermatitis and contact dermatitis. An important gene associated with Irritant Dermatitis is LCE5A (late cornified envelope 5A). The compounds calcipotriol and 1,25 dihydroxy vitamin d3 have been mentioned in the context of this disorder. Affiliated tissues include skin and testes.

Aliases & Classifications for Irritant Dermatitis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Related Diseases for Irritant Dermatitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Irritant Dermatitis:



Diseases related to irritant dermatitis

Clinical Features for Irritant Dermatitis

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Drugs & Therapeutics for Irritant Dermatitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Irritant Dermatitis

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Anatomical Context for Irritant Dermatitis

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32MalaCards
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MalaCards organs/tissues related to Irritant Dermatitis:

32
Skin, Testes

Animal Models for Irritant Dermatitis or affiliated genes

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Publications for Irritant Dermatitis

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50PubMed
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Articles related to Irritant Dermatitis:

(show top 50)    (show all 141)
idTitleAuthorsYear
1
Irritant contact dermatitis from a black henna tattoo without sensitization to para-phenylendiamine. (23690526)
2013
2
Facial contact dermatitis and the irritant potential of mobile phone screens. (23025548)
2013
3
Is dermatitis palmaris sicca an irritant contact dermatitis? (23665830)
2013
4
Cytokines and Chemokines in Irritant Contact Dermatitis. (24371376)
2013
5
Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis. (23039796)
2013
6
To evaluate the efficacy and safety of "RV2427B" cream in Irritant dermatitis care. (23984228)
2013
7
Chemicals inducing acute irritant contact dermatitis mobilize intracellular calcium in human keratinocytes. (22906572)
2013
8
Acute irritant threshold correlates with barrier function, skin hydration and contact hypersensitivity in atopic dermatitis and rosacea. (24112695)
2013
9
Clinical course of occupational irritant contact dermatitis of the hands in relation to filaggrin genotype status and atopy. (22962861)
2012
10
Irritant contact dermatitis: effect of age. (21967594)
2012
11
Oral administration of glucosylceramide ameliorates inflammatory dry-skin condition in chronic oxazolone-induced irritant contact dermatitis in the mouse ear. (22726258)
2012
12
Occupational irritant contact dermatitis caused by Lobelia richardii in an Ethiopian flower farm. (22775548)
2012
13
Irritant contact dermatitis due to the use of a continuous positive airway pressure nasal mask: 2 case reports and review of the literature. (23094310)
2012
14
Fiddler's neck: Chin rest-associated irritant contact dermatitis and allergic contact dermatitis in a violin player. (23031377)
2012
15
Anti-irritants agents for the treatment of irritant contact dermatitis: clinical and patent perspective. (22827755)
2012
16
Oxidative stress in allergic and irritant dermatitis: from basic research to clinical management. (22827837)
2012
17
Allergic or irritant contact dermatitis after patch testing with alcohol--that is the point. (23151199)
2012
18
Contact dermatitis caused by chlorothalonil on imported roses: irritant or allergic reaction? (21658059)
2011
19
Use of frozen poloxamer as a base for Itchy skin conditions, including irritant contact dermatitis. (21781082)
2011
20
Contact depigmentation following irritant contact dermatitis to chloroxylenol (Dettol). (21860168)
2011
21
Povidone iodine irritant dermatitis. (20606840)
2010
22
Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis. (19818069)
2010
23
Treatment with pimecrolimus cream 1% clears irritant dermatitis of the periocular region, face and neck. (18937664)
2008
24
Polymorphisms in the interleukin-1 gene influence the stratum corneum interleukin-1 alpha concentration in uninvolved skin of patients with chronic irritant contact dermatitis. (18416755)
2008
25
Airborne irritant contact dermatitis and conjunctivitis after occupational exposure to chlorothalonil in textiles. (17680869)
2007
26
Moisturizer effect on irritant dermatitis: an overview. (16930228)
2006
27
Irritant dermatitis due to prolonged contact with Oilatum Plus. (12534617)
2003
28
Importance of irritant contact dermatitis in occupational skin disease. (12010073)
2002
29
Irritant dermatitis, irritancy and its role in allergic contact dermatitis. (11952708)
2002
30
Sea water or its components alter experimental irritant dermatitis in man. (11301639)
2001
31
Lymphedema of the hand following recurrent erysipelas secondary to fissured irritant contact dermatitis. (10871118)
2000
32
Human barrier recovery after acute acetone perturbation: an irritant dermatitis model. (9667101)
1998
33
Adhesion molecules in atopic dermatitis: upregulation of alpha6 integrin expression in spontaneous lesional skin as well as in atopen, antigen and irritative induced patch test reactions. (9250597)
1997
34
Predictive testing in contact dermatitis. Irritant dermatitis. (9255475)
1997
35
Pigmented and hyperkeratotic napkin dermatitis: a liquid detergent irritant dermatitis. (8864616)
1996
36
Acute irritant dermatitis: effect of short-term topical corticoid treatment. (7587340)
1995
37
Sodium hydroxide-induced irritant dermatitis as assessed by computerized elaboration of 20 MHz B-scan images and by TEWL measurement: a method for investigating skin barrier function. (7604663)
1995
38
Occupational dermatitis in hairdressing apprentices. Early-onset irritant skin damage. (9035926)
1995
39
Irritant dermatitis among workers cleaning up a pesticide spill: California 1991. (7793424)
1995
40
The causes of irritant dermatitis. (8240913)
1993
41
Susceptibility of atopic dermatitis patients to irritant dermatitis caused by sodium lauryl sulphate. (1681644)
1991
42
Neuropeptides enhance irritant and allergic contact dermatitis. (1708795)
1991
43
Increased stratum corneum turnover induced by subclinical irritant dermatitis. (2369560)
1990
44
Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel. (2713259)
1989
45
Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol. (2960483)
1987
46
Prevention of irritant dermatitis. (2956714)
1986
47
Vulvar dermatitis and fissures--irritant dermatitis from methyl benzethonium chloride. (2936553)
1985
48
Irritant dermatitis due to Euphorbia marginata. (4042646)
1985
49
Temperature dependent primary irritant dermatitis from lemon perfume. (139284)
1977
50
Primary irritant dermatitis from the Manchineel tree (Hippomane mancineltal inthe Eastern Caribbean. (4461811)
1974

Genetic Variations for Irritant Dermatitis

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Expression for genes affiliated with Irritant Dermatitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Irritant Dermatitis

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Pathways for genes affiliated with Irritant Dermatitis

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Compounds for genes affiliated with Irritant Dermatitis

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Sources:
44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Irritant Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcipotriol44 59 28 1112.7KRT16, IL1A
21,25 dihydroxy vitamin d3449.7KRT16, IL1A
3sodium dodecylsulfate449.4KRT16, IL1A
4vitamin a44 11 2411.2KRT16, IL1A, LOR

GO Terms for genes affiliated with Irritant Dermatitis

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16Gene Ontology
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Biological processes related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1epidermis developmentGO:0085449.5KRT16, LCE2B
2keratinizationGO:0314247.9HRNR, LCE2B, LCE5A, LCE3A, LOR

Molecular functions related to Irritant Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.8KRT16, LOR

Products for genes affiliated with Irritant Dermatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Irritant Dermatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet