MCID: IRR003
MIFTS: 45

Irritant Dermatitis

Categories: Skin diseases

Aliases & Classifications for Irritant Dermatitis

Summaries for Irritant Dermatitis

MalaCards based summary : Irritant Dermatitis, also known as dermatitis, irritant, is related to burns and dermatitis, atopic. An important gene associated with Irritant Dermatitis is IL1A (Interleukin 1 Alpha), and among its related pathways/superpathways are Developmental Biology and Allograft rejection. The drugs Clobetasol and Glycerol have been mentioned in the context of this disorder. Affiliated tissues include skin and testes.

Wikipedia : 72 Irritant contact dermatitis is a form of contact dermatitis that can be divided into forms caused by... more...

Related Diseases for Irritant Dermatitis

Diseases related to Irritant Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 101)
# Related Disease Score Top Affiliating Genes
1 burns 30.0 IL1B TNF
2 dermatitis, atopic 29.9 FLG MS4A2 TNF
3 allergic contact dermatitis 29.9 FLG IL1B TNF
4 contact dermatitis 29.5 FLG IL1A IL1B KRT16 TNF
5 dermatitis 10.7
6 sebaceous gland disease 10.4 IER3IP1 IL1A
7 skin conditions 10.4 IL1A TNF
8 paratyphoid fever 10.4 IL1A TNF
9 chronic follicular conjunctivitis 10.4 IL1A IL1B
10 melancholia 10.4 IER3IP1 TNF
11 discoid lupus erythematosus 10.4 FLG KRT16
12 glossitis 10.4 KRT16 TNF
13 palmoplantar keratoderma, nonepidermolytic 10.4 FLG KRT16
14 dysentery 10.4 IER3IP1 IL1A
15 multidrug-resistant tuberculosis 10.3 IL1A TNF
16 post-transplant lymphoproliferative disease 10.3 IL1A TNF
17 limbal stem cell deficiency 10.3 IL1A IL1B
18 meningococcemia 10.3 IL1A IL1B
19 polyposis, gastric 10.3 IL1B TNF
20 systemic onset juvenile idiopathic arthritis 10.3 IL1B TNF
21 staphylococcal toxic shock syndrome 10.3 IL1B TNF
22 kashin-beck disease 10.3 IL1B TNF
23 vulvar vestibulitis syndrome 10.3 IL1B TNF
24 rosacea 10.3 IER3IP1 TNF
25 laryngitis 10.3 IL1B TNF
26 cerebral artery occlusion 10.3 IL1B TNF
27 haemophilus influenzae 10.3 IL1B TNF
28 retinitis pigmentosa 60 10.3 IL1B TNF
29 acute vascular insufficiency of intestine 10.3 IL1B TNF
30 actinic prurigo 10.3 IL1B TNF
31 poems syndrome 10.3 IL1B TNF
32 crohn's colitis 10.2 IL1B TNF
33 burning mouth syndrome 10.2 IL1B TNF
34 central nervous system vasculitis 10.2 IL1B TNF
35 dental pulp disease 10.2 IL1B TNF
36 osteosclerotic myeloma 10.2 IL1B TNF
37 jejunoileitis 10.2 IL1B TNF
38 eales disease 10.2 IL1B TNF
39 aseptic meningitis 10.2 IL1B TNF
40 blau syndrome 10.2 IL1B TNF
41 endometritis 10.2 IL1B TNF
42 pulpitis 10.2 IL1B TNF
43 scrub typhus 10.2 IL1B TNF
44 pustular psoriasis 10.2 PI3 TNF
45 farmer's lung 10.2 PI3 TNF
46 joint disorders 10.2 IL1B TNF
47 lichen planus 10.2 FLG KRT16 TNF
48 root resorption 10.1 IL1A IL1B
49 erysipelas 10.1 PI3 TNF
50 lacrimal apparatus disease 10.1 IL1B TNF

Graphical network of the top 20 diseases related to Irritant Dermatitis:



Diseases related to Irritant Dermatitis

Symptoms & Phenotypes for Irritant Dermatitis

Drugs & Therapeutics for Irritant Dermatitis

Drugs for Irritant Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clobetasol Approved, Investigational Phase 4 25122-41-2, 25122-46-7 5311051 32798
2
Glycerol Approved, Investigational Phase 4 56-81-5 753
3
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Menthol Approved Phase 4 2216-51-5 16666
6
Zinc Approved, Investigational Phase 4,Not Applicable 7440-66-6 32051 23994
7
Zinc oxide Approved Phase 4,Not Applicable 1314-13-2
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 1 22916-47-8 4189
9 Tocopherol Approved, Investigational, Nutraceutical Phase 4
10
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
11 Anti-Inflammatory Agents Phase 4
12 Calcineurin Inhibitors Phase 4
13 glucocorticoids Phase 4
14 Hormone Antagonists Phase 4,Phase 1
15 Hormones Phase 4,Phase 1
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 1
17 Immunosuppressive Agents Phase 4
18 Protective Agents Phase 4,Phase 2,Not Applicable
19 triamcinolone acetonide Phase 4
20 Triamcinolone diacetate Phase 4
21 Triamcinolone hexacetonide Phase 4
22 Antipruritics Phase 4
23 Dermatologic Agents Phase 4,Phase 1,Phase 2,Not Applicable
24 Micronutrients Phase 4,Not Applicable
25 Radiation-Protective Agents Phase 4,Phase 2,Not Applicable
26 Sunscreening Agents Phase 4,Phase 2,Not Applicable
27 Trace Elements Phase 4,Not Applicable
28 Antifungal Agents Phase 4,Phase 1
29 Anti-Infective Agents Phase 4,Phase 1
30 Cytochrome P-450 CYP2C9 Inhibitors Phase 4
31 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 1
32 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 1
33 Steroid Synthesis Inhibitors Phase 4,Phase 1
34 Antioxidants Phase 4
35 Tocopherols Phase 4
36 Tocotrienols Phase 4
37 Vitamins Phase 4
38 Aloe Nutraceutical Phase 4
39 Tocotrienol Investigational, Nutraceutical Phase 4 6829-55-6
40
Aminolevulinic acid Approved Phase 1, Phase 2 106-60-5 137
41 Pharmaceutical Solutions Phase 2
42 Methyl 5-aminolevulinate Phase 1, Phase 2
43 Photosensitizing Agents Phase 1, Phase 2
44
Doxycycline Approved, Investigational, Vet_approved Phase 1 564-25-0 54671203
45
Voriconazole Approved, Investigational Phase 1 137234-62-9 71616
46 Anti-Bacterial Agents Phase 1
47 Antimalarials Phase 1
48 Antiparasitic Agents Phase 1
49 Antiprotozoal Agents Phase 1
50 Coconut Approved, Nutraceutical Not Applicable

Interventional clinical trials:

(show all 33)

# Name Status NCT ID Phase Drugs
1 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
2 Trial Comparing Calmoseptine Ointment and Desitin Diaper Rash Paste in Diaper Dermatitis in Neonates and Infants Unknown status NCT02716415 Phase 4 Calmoseptine Ointment;Destin Maximum Strength 40% Zinc
3 Prospective Two-Year Study to Assess Miconazole Nitrate Resistance in Neonates and Infants Completed NCT00702507 Phase 4 0.25 % Miconazole Nitrate Ointment
4 Clinical Study to Evaluate the Efficacy and Safety of Two Marketed Investigational Products in Children With Diaper Rash Completed NCT00219466 Phase 4
5 Determination of Safety and Consumers' Satisfaction of Moussik Versus Desitin Creamy Ointment in Diaper Rash Prophylaxis Withdrawn NCT01167465 Phase 4
6 COLLAGEN CROSS-LINKING WITH ULTRAVIOLET-A IN ASYMMETRIC CORNEAS Recruiting NCT03029104 Phase 2 CXLO Corneal Strengthening Solution and UVA Illumination
7 Superficial Basal Cell Cancer's Photodynamic Therapy: Comparing Three Photosensitises: HAL and BF-200 ALA Versus MAL Recruiting NCT02367547 Phase 1, Phase 2 Hexylaminolevulinate cream;Aminolevulinic Acid Nano Emulsion;Methylaminolevulinate cream
8 Efficacy and Safety of a Sunscreen Against Porfimer Sodium-induced Phototoxicity to Visible Light Withdrawn NCT01256203 Phase 2 Solar Protection Formula SPF® 60
9 A 4-Day Study to Evaluate Phototoxicity of CCP-020 (Diacerein 1%) in Healthy Subjects Completed NCT03473184 Phase 1 CCP-020 Diacerein 1% topical ointment;Vehicle
10 A Study Evaluating Skin Irritation, Phototoxicity and Safety After Administration of LEO 90105 on Intact Skin of Healthy Japanese Male Subjects Completed NCT01293357 Phase 1 LEO 90105
11 A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity Completed NCT00353158 Phase 1 Doxycycline;Voriconazole
12 A Randomised Clinical Trial in a Population of Health Care Workers With Hand Eczema Unknown status NCT01012453
13 Regional Differences of Cutaneous Irritation and Its Effect on Skin Barrier Recovery Completed NCT03231813
14 Effect of Tetrix on Alleviation of Burning,Itching Associated With Lesions of Contact Dermatitis Completed NCT00646867
15 Risk Factors for Incontinence-Associated Dermatitis (IAD) in ICU Patients Suffering From Fecal Incontinence Completed NCT02996357
16 BM Collection From NICU Infants for Composition Completed NCT02570698
17 BM Characterization Pilot Completed NCT03138057
18 Infant Microbiome in Diaper Rash Completed NCT02893501
19 Human Phototoxicity Test (823/2016) Completed NCT02962856 Not Applicable BAY987517
20 18348-Human Phototoxicity Test Completed NCT02823483 Not Applicable
21 Test the Phototoxicity of Sunscreen Products Completed NCT02802930 Not Applicable SPF 50 Y65 110 (BAY987519);SPF 50 Y51 002 (BAY987519);SPF 15 V27 104 (BAY987519);Sodium chloride [NaCl]
22 Human Phototoxicity Test Completed NCT02754102 Not Applicable
23 Human Phototoxicity Test Completed NCT02751541 Not Applicable Sunscreen Sport Spray (BAY987519)
24 Human Phototoxicity Test Completed NCT02751489 Not Applicable
25 Human Phototoxicity Test Completed NCT02750475 Not Applicable Sunscreen Sport Lotion (BAY987516)
26 The Use of Coconut Oil for the Prevention and Treatment of Diaper Dermatitis in the NICU Population Recruiting NCT02614248 Not Applicable
27 Comparison of Barrier Products in the Prevention of Incontinence-associated Dermatitis in Hospitalized Elderly Recruiting NCT03309059 Not Applicable
28 Prevention of Phototoxicities in Patients Undergoing Vemurafenib Treatment Recruiting NCT03108209 Not Applicable
29 Diaper Distribution in Low-Income Infants Recruiting NCT03425851 Not Applicable
30 Preliminary Evaluation of CASTLE Barrier Prototype UK Terminated NCT01530087
31 Comparison of Wash Wipes and Standard Care in the Prevention of Incontinence-associated Dermatitis in Elderly Terminated NCT02475512
32 CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants Terminated NCT02299206 Not Applicable CeraVe Baby Diaper Rash Cream;Desitin Maximum Strength Original Paste
33 Vulvar Contact Dermatitis Resulting From Urine Incontinence Withdrawn NCT01320046

Search NIH Clinical Center for Irritant Dermatitis

Cochrane evidence based reviews: dermatitis, irritant

Genetic Tests for Irritant Dermatitis

Anatomical Context for Irritant Dermatitis

MalaCards organs/tissues related to Irritant Dermatitis:

38
Skin, Testes

Publications for Irritant Dermatitis

Articles related to Irritant Dermatitis:

(show top 50) (show all 73)
# Title Authors Year
1
Topical ROR inverse agonists suppress inflammation in mouse models of atopic dermatitis and acute irritant dermatitis. ( 28774591 )
2017
2
Preapplication of white petroleum jelly to adjacent skin to prevent aluminum chloride-induced irritant dermatitis. ( 28619576 )
2017
3
N-acyl ethanolamide and eicosanoid involvement in irritant dermatitis. ( 26947140 )
2016
4
IL-6 deficiency exacerbates skin inflammation in a murine model of irritant dermatitis. ( 22966985 )
2013
5
To evaluate the efficacy and safety of "RV2427B" cream in Irritant dermatitis care. ( 23984228 )
2013
6
Hand hygiene compliance and irritant dermatitis: a juxtaposition of healthcare issues. ( 22691060 )
2012
7
Allergic and irritant dermatitis: pathogenic and management aspects. ( 22827836 )
2012
8
Contact irritant dermatitis in Kenya. ( 23472569 )
2012
9
Oxidative stress in allergic and irritant dermatitis: from basic research to clinical management. ( 22827837 )
2012
10
Hair highlights and severe acute irritant dermatitis ("burn") of the scalp. ( 20854194 )
2010
11
IL-6, VEGF, KC and RANTES are a major cause of a high irritant dermatitis to phthalic anhydride in C57BL/6 inbred mice. ( 20864798 )
2010
12
WOC nurse consult: Moist, painful peristomal skin. Chemical irritant dermatitis and pseudoverrucous lesions. ( 20228658 )
2010
13
Irritant Dermatitis to Staphylinid Beetle in Indian Troops in Congo. ( 27375320 )
2010
14
Povidone iodine irritant dermatitis. ( 20606840 )
2010
15
Contact irritant dermatitis from insect secretions: report of 74 cases in a military unit in Eritrea. ( 19731793 )
2009
16
Recurrent cyclic hyperkeratotic eczema after occupational alkali burn: traumatic chronic irritant dermatitis. ( 19489972 )
2009
17
Treatment with pimecrolimus cream 1% clears irritant dermatitis of the periocular region, face and neck. ( 18937664 )
2008
18
The effect of irritant dermatitis on cutaneous bioavailability of a metronidazole formulation, investigated by microdialysis and dermatopharmacokinetic method. ( 18537995 )
2008
19
Occlusive irritant dermatitis: when is "allergic" contact dermatitis not allergic? ( 17366682 )
2007
20
Contact and primary irritant dermatitis of the nail unit diagnosis and treatment. ( 17403259 )
2007
21
Moisturizer effect on irritant dermatitis: an overview. ( 16930228 )
2006
22
Effectiveness of a hand care regimen with moisturizer in manufacturing facilities where workers are prone to occupational irritant dermatitis. ( 15573643 )
2004
23
Contact irritant dermatitis and anti-pruritic agents: the need to address the itch. ( 12852365 )
2003
24
Irritant dermatitis to detergents in textiles. ( 12882025 )
2003
25
Irritant dermatitis due to prolonged contact with Oilatum Plus. ( 12534617 )
2003
26
Irritant dermatitis, irritancy and its role in allergic contact dermatitis. ( 11952708 )
2002
27
Sea water or its components alter experimental irritant dermatitis in man. ( 11301639 )
2001
28
Successfully managing incontinence-related irritant dermatitis across the lifespan. ( 10347509 )
1999
29
Crystal deodorant dermatitis: irritant dermatitis to alum-containing deodorant. ( 10431678 )
1999
30
Kerosene - Induced Acute Irritant Dermatitis (le). ( 20921732 )
1998
31
Human barrier recovery after acute acetone perturbation: an irritant dermatitis model. ( 9667101 )
1998
32
Arachidonic acid metabolism in primary irritant dermatitis produced by patch testing of human skin with surfactants. ( 9875300 )
1998
33
Predictive testing in contact dermatitis. Irritant dermatitis. ( 9255475 )
1997
34
What's new in irritant dermatitis. ( 9255463 )
1997
35
Pigmented and hyperkeratotic napkin dermatitis: a liquid detergent irritant dermatitis. ( 8864616 )
1996
36
Sodium hydroxide-induced irritant dermatitis as assessed by computerized elaboration of 20 MHz B-scan images and by TEWL measurement: a method for investigating skin barrier function. ( 7604663 )
1995
37
Irritant dermatitis: experimental aspects. ( 9035907 )
1995
38
Acute irritant dermatitis: effect of short-term topical corticoid treatment. ( 7587340 )
1995
39
Irritant dermatitis among workers cleaning up a pesticide spill: California 1991. ( 7793424 )
1995
40
Electrical impedance measured to five skin depths in mild irritant dermatitis induced by sodium lauryl sulphate. ( 7772476 )
1995
41
Irritant dermatitis in the workplace. ( 7923942 )
1994
42
The causes of irritant dermatitis. ( 8240913 )
1993
43
Moisturizers prevent irritant dermatitis. ( 1350143 )
1992
44
Susceptibility of atopic dermatitis patients to irritant dermatitis caused by sodium lauryl sulphate. ( 1681644 )
1991
45
Increased stratum corneum turnover induced by subclinical irritant dermatitis. ( 2369560 )
1990
46
Susceptibility to irritant dermatitis induced by sodium lauryl sulfate. ( 2365862 )
1990
47
Quantification of sodium lauryl sulfate irritant dermatitis in man: comparison of four techniques: skin color reflectance, transepidermal water loss, laser Doppler flow measurement and visual scores. ( 2774663 )
1989
48
Cumulative irritant dermatitis and abnormal epidermal plasminogen activator activity: what connection? ( 2531125 )
1989
49
Susceptibility to cumulative and acute irritant dermatitis. An experimental approach in human volunteers. ( 3180788 )
1988
50
Pustular irritant dermatitis due to croton oil. Evaluation of the role played by leukocytes and complement. ( 2455422 )
1988

Variations for Irritant Dermatitis

Expression for Irritant Dermatitis

Search GEO for disease gene expression data for Irritant Dermatitis.

Pathways for Irritant Dermatitis

Pathways related to Irritant Dermatitis according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.27 FLG KRT16 LCE2B PI3 PKP3 TNF
2
Show member pathways
12.65 IL1A IL1B MS4A2 TNF
3
Show member pathways
12.08 IL1A IL1B TNF
4
Show member pathways
12.07 IL1A IL1B TNF
5 12.05 IL1A IL1B TNF
6
Show member pathways
12.03 IL1A IL1B TNF
7 11.98 IL1A IL1B TNF
8
Show member pathways
11.94 IL1A IL1B TNF
9 11.89 IL1A IL1B TNF
10 11.83 IL1A IL1B TNF
11 11.78 IL1A IL1B TNF
12 11.74 IL1A IL1B TNF
13 11.67 IL1A IL1B TNF
14 11.64 IL1A IL1B TNF
15 11.59 IL1A IL1B TNF
16 11.49 IL1A IL1B TNF
17
Show member pathways
11.48 FLG KRT16 LCE2B PI3 PKP3
18
Show member pathways
11.34 IL1A IL1B TNF
19 11.19 IL1B TNF
20 11.19 IL1A IL1B
21 11.19 IL1A IL1B TNF
22 11.14 IL1B TNF
23 11.12 IL1B TNF
24 11.09 IL1A IL1B TNF
25 11.03 IL1A IL1B TNF
26 10.93 IL1B TNF
27 10.88 IL1A IL1B TNF
28 10.74 IL1B TNF
29 10.61 IL1A IL1B TNF
30 10.25 IL1A IL1B

GO Terms for Irritant Dermatitis

Cellular components related to Irritant Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.92 FLG LCE2B PI3 PKP3

Biological processes related to Irritant Dermatitis according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.92 IL1A IL1B MS4A2 TNF
2 positive regulation of gene expression GO:0010628 9.87 IL1A IL1B PKP3 TNF
3 keratinization GO:0031424 9.83 KRT16 LCE2B PKP3
4 keratinocyte differentiation GO:0030216 9.69 FLG KRT16 LCE2B
5 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 IL1B TNF
6 positive regulation of phagocytosis GO:0050766 9.65 IL1B TNF
7 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.64 IL1A IL1B
8 positive regulation of cytokine secretion GO:0050715 9.64 IL1A TNF
9 positive regulation of interleukin-8 production GO:0032757 9.63 IL1B TNF
10 positive regulation of vascular endothelial growth factor production GO:0010575 9.63 IL1A IL1B
11 positive regulation of mitotic nuclear division GO:0045840 9.62 IL1A IL1B
12 positive regulation of NF-kappaB import into nucleus GO:0042346 9.61 IL1B TNF
13 positive regulation of interleukin-6 secretion GO:2000778 9.61 IL1B NLRP10
14 establishment of skin barrier GO:0061436 9.6 FLG KRT16
15 negative regulation of lipid catabolic process GO:0050995 9.59 IL1B TNF
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.58 IL1B TNF
17 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.58 IL1B TNF
18 peptide cross-linking GO:0018149 9.58 FLG LCE2B PI3
19 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.56 IL1B TNF
20 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.55 IL1A IL1B
21 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.54 IL1A IL1B
22 positive regulation of chemokine biosynthetic process GO:0045080 9.52 IL1B TNF
23 positive regulation of interleukin-6 production GO:0032755 9.5 IL1A IL1B TNF
24 regulation of establishment of endothelial barrier GO:1903140 9.49 IL1B TNF
25 ectopic germ cell programmed cell death GO:0035234 9.48 IL1A IL1B
26 fever generation GO:0001660 9.46 IL1A IL1B
27 positive regulation of fever generation GO:0031622 9.43 IL1B TNF
28 sequestering of triglyceride GO:0030730 9.37 IL1B TNF
29 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.33 IL1A IL1B TNF
30 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.26 IL1B TNF
31 cornification GO:0070268 9.26 FLG KRT16 PI3 PKP3
32 inflammatory response GO:0006954 9.1 IL1A IL1B KRT16 MS4A2 NLRP10 TNF

Molecular functions related to Irritant Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.33 IL1A IL1B TNF
2 interleukin-1 receptor binding GO:0005149 8.96 IL1A IL1B
3 structural constituent of epidermis GO:0030280 8.62 FLG PI3

Sources for Irritant Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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