MCID: ISC002
MIFTS: 37

Ischemic Optic Neuropathy malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Ischemic Optic Neuropathy

Aliases & Descriptions for Ischemic Optic Neuropathy:

Name: Ischemic Optic Neuropathy 38
Optic Neuropathy, Ischemic 69

Classifications:



Summaries for Ischemic Optic Neuropathy

MalaCards based summary : Ischemic Optic Neuropathy, also known as optic neuropathy, ischemic, is related to nonarteritic anterior ischemic optic neuropathy and arteritic anterior ischemic optic neuropathy. An important gene associated with Ischemic Optic Neuropathy is GP1BA (Glycoprotein Ib Platelet Alpha Subunit), and among its related pathways/superpathways are Platelet activation and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs Dorzolamide and Timolol have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and neutrophil.

Wikipedia : 71 Ischemic optic neuropathy (ION) is the loss of structure and function of a portion of the optic nerve... more...

Related Diseases for Ischemic Optic Neuropathy

Diseases related to Ischemic Optic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 142)
id Related Disease Score Top Affiliating Genes
1 nonarteritic anterior ischemic optic neuropathy 12.7
2 arteritic anterior ischemic optic neuropathy 12.5
3 neuropathy 11.1
4 retinitis 10.5
5 optic neuritis 10.3
6 neuritis 10.3
7 choroiditis 10.2
8 retinal artery occlusion 10.2
9 sleep apnea 10.1
10 intracranial cysts 10.1 MTHFR NOS3
11 glutathionuria 10.1 MTHFR NOS3
12 central retinal artery occlusion 10.1
13 ocular hyperemia 10.1 GP1BA MTHFR
14 capillary hemangioma 10.1 MTHFR NOS3
15 pars planitis 10.1 ACE MTHFR
16 iris disease 10.1 ACE NOS3
17 bullous skin disease 10.1 ACE MTHFR
18 eye degenerative disease 10.1 ACE NOS3
19 joint disorders 10.1 ACE NOS3
20 obstructive sleep apnea 10.1
21 cataract 10.1
22 aplasia cutis congenita recessive 10.1 ACE NOS3
23 lymphadenitis 10.1 ACE NOS3
24 hypertrichosis of eyelid 10.1 ACE MTHFR
25 interstitial emphysema 10.0 ACE MTHFR
26 focal dystonia 10.0 ACE NOS3
27 acute posterior multifocal placoid pigment epitheliopathy 10.0 ACE NOS3
28 oppositional defiant disorder 10.0 ACE NOS3
29 cerebral convexity meningioma 10.0 ACE NOS3
30 intra-abdominal lymph node mast cell malignancy 10.0 ACE MTHFR
31 endotheliitis 10.0
32 hepatitis 10.0
33 retinal vein occlusion 10.0
34 hepatitis c 10.0
35 pyelonephritis 10.0 ACE NOS3
36 vernal conjunctivitis 10.0 ACE MTHFR
37 neurofibroma of the heart 10.0 MTHFR NOS3
38 limb ischemia 10.0 ACE NOS3
39 contagious pustular dermatitis 10.0 ACE MTHFR
40 diabetic encephalopathy 10.0 ACE NOS3
41 rectal prolapse 10.0 NOS3 PDE5A
42 gastrointestinal lymphoma 10.0 ACE NOS3
43 bone development disease 10.0 GP1BA MTHFR
44 traumatic glaucoma 10.0 NOS3 PDE5A
45 welander distal myopathy 10.0 MTHFR NOS3
46 peritonitis 10.0
47 thrombophilia 10.0
48 open-angle glaucoma 10.0
49 citrullinemia, type ii, neonatal-onset 10.0 ACE NOS3
50 pythiosis 9.9 ACE PDE5A

Graphical network of the top 20 diseases related to Ischemic Optic Neuropathy:



Diseases related to Ischemic Optic Neuropathy

Symptoms & Phenotypes for Ischemic Optic Neuropathy

Drugs & Therapeutics for Ischemic Optic Neuropathy

Drugs for Ischemic Optic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 102)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
2
Timolol Approved Phase 4,Phase 1 26839-75-8 33624 5478
3
4-Aminopyridine Approved Phase 4 504-24-5 1727
4
Carbidopa Approved Phase 4 28860-95-9 34359 38101
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Levodopa Approved Phase 4 59-92-7 6047
7
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
8
Ephedrine Approved Phase 4 299-42-3 9294
9
Pseudoephedrine Approved Phase 4 90-82-4 7028
10
Choline Approved, Nutraceutical Phase 4 62-49-7 305
11 Adrenergic Agents Phase 4,Phase 1
12 Adrenergic Antagonists Phase 4,Phase 1
13 Adrenergic beta-Antagonists Phase 4,Phase 1
14 Anti-Arrhythmia Agents Phase 4,Phase 1
15 Antihypertensive Agents Phase 4,Phase 3,Phase 1
16 Carbonic Anhydrase Inhibitors Phase 4
17 Neurotransmitter Agents Phase 4,Phase 2,Phase 1
18 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Gastrointestinal Agents Phase 4,Phase 3,Phase 1,Phase 2
20 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
21 Potassium Channel Blockers Phase 4
22 Adjuvants, Immunologic Phase 4
23 Antiparkinson Agents Phase 4
24 Aromatic Amino Acid Decarboxylase Inhibitors Phase 4
25 Carbidopa, levodopa drug combination Phase 4
26 Dopamine Agents Phase 4
27 Dopamine agonists Phase 4
28 Cytidine Diphosphate Choline Phase 4
29 Nootropic Agents Phase 4
30 Phosphodiesterase 5 Inhibitors Phase 4
31 Phosphodiesterase Inhibitors Phase 4,Phase 2
32 Sildenafil Citrate Phase 4 171599-83-0
33 Vardenafil Dihydrochloride Phase 4
34 Adrenergic Agonists Phase 4
35 Adrenergic alpha-2 Receptor Agonists Phase 4
36 Adrenergic alpha-Agonists Phase 4
37 Brimonidine Tartrate Phase 4 70359-46-5
38 Carboxymethylcellulose Sodium Phase 4
39 Cathartics Phase 4
40 Laxatives Phase 4
41 Nasal Decongestants Phase 4
42 Ophthalmic Solutions Phase 4
43 Pharmaceutical Solutions Phase 4,Phase 2
44 Respiratory System Agents Phase 4,Phase 2
45 Tetrahydrozoline Phase 4
46 Vasoconstrictor Agents Phase 4
47
Methylprednisolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 83-43-2 6741
48
Prednisolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 50-24-8 5755
49
Triamcinolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 124-94-7 31307
50
Bosentan Approved, Investigational Phase 3 147536-97-8 104865

Interventional clinical trials:

(show top 50) (show all 54)
id Name Status NCT ID Phase
1 Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients Unknown status NCT02053298 Phase 4
2 A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT01975324 Phase 4
3 Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy Completed NCT00432393 Phase 4
4 Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases Completed NCT00404729 Phase 4
5 Ophthalmic Findings During 10-year Enzyme Substitution of Danish Fabry Patients. Completed NCT01997489 Phase 4
6 PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT00867815 Phase 4
7 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT03046693 Phase 4
8 Preoperative Brimonidine on IOP of Patients Undergoing RALP Recruiting NCT02818816 Phase 4
9 Outcomes of Steroid and Oxygen Therapy Versus Placebo Therapy in Non-arteritic Anterior Ischemic Optic Neuropathy Unknown status NCT02439866 Phase 3
10 Retrobulbar Triamcinolone Acetonide Injection in the Treatment of NA-AION Unknown status NCT02329288 Phase 3
11 Ischemic Optic Neuropathy Decompression Trial (IONDT) Completed NCT00000127 Phase 3
12 Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT02341560 Phase 2, Phase 3
13 Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study) Recruiting NCT02376881 Phase 3
14 ENDOTHELION Study Group: Effect of Bosentan in NAION Patients Not yet recruiting NCT02377271 Phase 3
15 Intravitreal Bevacizumab for Non-Arteritic Anterior Ischemic Optic Neuropathy Unknown status NCT00813059 Phase 2
16 Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo Unknown status NCT01330524 Phase 1, Phase 2
17 Safety and Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION). Completed NCT02045212 Phase 2
18 Neurotomy of Optic Nerve in Non-Arthritic Anterior Ischemic Optic Neuropathy Completed NCT00372021 Phase 1, Phase 2
19 Effects of Moxaverine and Placebo on Ocular Blood Flow Completed NCT00709423 Phase 2
20 Traumatic Optic Neuropathy Treatment Trial (TONTT) Completed NCT01783847 Phase 1, Phase 2
21 Safety Assessment of Intravitreal Mesenchymal Stem Cells for Acute Non Arteritic Anterior Ischemic Optic Neuropathy Not yet recruiting NCT03173638 Phase 2
22 Intraocular Pressure During Prone Spinal Surgery Terminated NCT00176722 Phase 2
23 Role of Endothelin- and Nitric Oxide-system in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure Withdrawn NCT00406731 Phase 2
24 Ranibizumab Therapy for Non-arteritic Ischemic Optic Neuropathy Completed NCT00561834 Phase 1
25 NT-501 CNTF Implant for Ischemic Optic Neuropathy: Safety, Neuroprotection and Neuroenhancement Completed NCT01411657 Phase 1
26 Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients Completed NCT01064505 Phase 1
27 A Phase I Clinical Trial of DARC Active, not recruiting NCT02394613 Phase 1
28 Treatment Study for Ischemic Optic Neuropathy With Opthalmic Timolol Maleate 0.5% Withdrawn NCT01607671 Phase 1
29 Ischemic Optic Neuropathy Decompression Trial Followup (IONDT Followup) Unknown status NCT00000126
30 Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS) Unknown status NCT00874913
31 Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins Unknown status NCT01794442
32 Epidemiology Study of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT01260324
33 Assessment of Visual Field-related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy Completed NCT01614158
34 A Study to Determine if There is a Possible Association Between Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) and Phosphodiesterase Type 5 (PDE5) Inhibitors Completed NCT01131104
35 Vision Restoration Therapy (VRT) to Treat Non-Arteritic Anterior Ischemic Optic Neuropathy Completed NCT00140491
36 Intraocular Pressure During Abdominal Aortic Aneurysm (AAA) Repair Completed NCT00450294
37 Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours Completed NCT00875043
38 Effects of Sevoflurane and Propofol on Light Flashed Evoked Pupillometry Completed NCT01219569
39 Transcorneal Electrical Stimulation Therapy for Retinal Disease Completed NCT00804102
40 Validation of the GATE Software Completed NCT01265628
41 A Study to Assess Whether PDE5 Inhibitors Increase the Chance of Triggering the Onset of Acute NAION Completed NCT00759174
42 Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation Completed NCT01391247
43 Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS) Completed NCT00610402
44 Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases Completed NCT02308579
45 Effect of EECP on Anterior Ischemic Optic Neuropathy Recruiting NCT01768260
46 Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy Recruiting NCT01338389
47 Biomechanics of Optic Neuropathy Recruiting NCT02982499
48 Stem Cell Ophthalmology Treatment Study II Recruiting NCT03011541
49 Stem Cell Ophthalmology Treatment Study Recruiting NCT01920867
50 Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders Recruiting NCT02836327

Search NIH Clinical Center for Ischemic Optic Neuropathy

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Ischemic Optic Neuropathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Ischemic Optic Neuropathy:
Renexus
Embryonic/Adult Cultured Cells Related to Ischemic Optic Neuropathy:
Human retinal stem cells secreting CNTF PMIDs: 16805711 17508034 16505355 23049090 15684670 12581701 15223826 18830926

Genetic Tests for Ischemic Optic Neuropathy

Anatomical Context for Ischemic Optic Neuropathy

MalaCards organs/tissues related to Ischemic Optic Neuropathy:

39
Eye, Endothelial, Neutrophil, Liver, Testes, B Cells, Prostate

Publications for Ischemic Optic Neuropathy

Articles related to Ischemic Optic Neuropathy:

(show top 50) (show all 668)
id Title Authors Year
1
Aqueous Humor Cytokines in Patients With Acute Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28302535 )
2017
2
Relative Frequencies of Arteritic and Nonarteritic Anterior Ischemic Optic Neuropathy in an Arab Population. ( 28099197 )
2017
3
Neutrophil to Lymphocyte Ratio in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28367045 )
2017
4
Nonarteritic Anterior Ischemic Optic Neuropathy and Intraocular Surgery. ( 28108001 )
2017
5
Assessment of nonarteritic anterior ischemic optic neuropathy with intravoxel incoherent motion diffusion-weighted imaging using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition. ( 28513892 )
2017
6
New Treatments for Nonarteritic Anterior Ischemic Optic Neuropathy. ( 27886887 )
2017
7
Increased Risk of Stroke in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy: A Nationwide Retrospective CohortA Study. ( 28063480 )
2017
8
Optical Coherence Tomography Angiography in Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28301863 )
2017
9
Takayasu arteritis presenting as isolated anterior ischemic optic neuropathy. ( 28389774 )
2017
10
Retinal Vessel Density in Optical Coherence Tomography Angiography in Optic Atrophy after Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28316838 )
2017
11
Perioperative nonarteritic anterior ischemic optic neuropathy in Jehovah's Witnesses. ( 28457303 )
2017
12
Aqueous Humor Cytokines in Patients With Acute Nonarteritic Anterior Ischemic Optic Neuropathy. ( 28438311 )
2017
13
Pathology of Ischemic Optic Neuropathy. ( 28029908 )
2017
14
Increased Risk of Stroke in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy: A Nationwide Retrospective Cohort Study. ( 28093100 )
2017
15
Erectile Dysfunction Agents and Nonarteritic Anterior Ischemic Optic Neuropathy. ( 27886893 )
2017
16
Prospective Case-crossover Study Investigating the Possible Association Between Nonarteritic Anterior Ischemic Optic Neuropathy and Phosphodiesterase Type 5 Inhibitor Exposure. ( 28336289 )
2017
17
Comparison of Visual Outcomes of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients with and without Diabetes Mellitus. ( 28017420 )
2016
18
Giant Cell Arteritis With Arteritic Anterior Ischemic Optic Neuropathy Is Bilateral Until Proven Otherwise. ( 27855128 )
2016
19
Efficacy of Intravitreal Injections of Triamcinolone Acetonide in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy. ( 27082303 )
2016
20
Imaging of macrophage dynamics with optical coherence tomography in anterior ischemic optic neuropathy. ( 27914988 )
2016
21
Trying to Understand Nonarteritic Anterior Ischemic Optic Neuropathy through Big Data. ( 27871391 )
2016
22
Clinical and color Doppler imaging features of one patient with occult giant cell arteritis presenting arteritic anterior ischemic optic neuropathy. ( 27516038 )
2016
23
Comment on: An unusual presentation of nonarteritic ischemic optic neuropathy with subretinal fluid treated with intravitreal bevacizumab. ( 27609174 )
2016
24
Anterior ischemic optic neuropathy and hematologic malignancy: a systematic review of case reports and case series. ( 27938958 )
2016
25
Early macular ganglion cell-inner plexiform layer analysis in non-arteritic anterior ischemic optic neuropathy. ( 26631135 )
2016
26
The Relationship Between Phosphodiesterase-5 Inhibitors and Nonarteritic Anterior Ischemic Optic Neuropathy. ( 26720519 )
2016
27
Temporal Arteritis With Arteritic Anterior Ischemic Optic Neuropathy is Bilateral Until Proven Otherwise: Response. ( 27855129 )
2016
28
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION). ( 27911358 )
2016
29
The 14th Hoyt Lecture: Ischemic Optic Neuropathy: The Evolving Profile, 1966-2015. ( 27176556 )
2016
30
Comparison of the Deep Optic Nerve Head Structure between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy. ( 27035660 )
2016
31
Bilateral simultaneous anterior ischemic optic neuropathy, an extrahepatic manifestation of hepatitis C cured with direct acting antivirals. ( 27625964 )
2016
32
Retinal Ganglion Cell Layer Thinning Within One Month of Presentation for Non-Arteritic Anterior Ischemic Optic Neuropathy. ( 27388052 )
2016
33
Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): A Review and Update on Animal Models. ( 26959135 )
2016
34
SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury. ( 27560494 )
2016
35
An unusual presentation of nonarteritic ischemic optic neuropathy with subretinal fluid treated with intravitreal bevacizumab. ( 26953030 )
2016
36
Peripapillary Retinal Nerve Fiber Layer Swelling Predicts Peripapillary Atrophy in a Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy. ( 26868755 )
2016
37
Could Topical Minoxidil Cause Non-Arteritic Anterior Ischemic Optic Neuropathy? ( 27656541 )
2016
38
Where Is the Lesion in Posterior Ischemic Optic Neuropathy Occurring After Prone Spine Surgery? ( 27428467 )
2016
39
The effect of high-dose steroids, and normobaric oxygen therapy, on recent onset non-arteritic anterior ischemic optic neuropathy: a randomized clinical trial. ( 27510295 )
2016
40
Nonarteritic anterior ischemic optic neuropathy following pars plana vitrectomy for macular hole treatment: case report. ( 27982219 )
2016
41
Comparison of the Pattern of Macular Ganglion Cell-Inner Plexiform Layer Defect Between Ischemic Optic Neuropathy and Open-Angle Glaucoma. ( 26962697 )
2016
42
Postoperative posterior ischemic optic neuropathy (PION) following right pterional meningioma surgery. ( 27570391 )
2016
43
Ganglion cell analysis at acute episode of nonarteritic anterior ischemic optic neuropathy to predict irreversible damage. A prospective study. ( 27422787 )
2016
44
Nonarteritic Ischemic Optic Neuropathy Associated With Clomiphene Citrate Use. ( 27941402 )
2016
45
Nonarteritic Anterior Ischemic Optic Neuropathy and Erectile Dysfunction Drugs: Is There an Elephant in the Bedroom? ( 27984350 )
2016
46
Bilateral septic cavernous sinus thrombosis, congestive orbitopathy, and ischemic optic neuropathy. ( 27085286 )
2016
47
Optic Nerve Head Morphology in Nonarteritic Anterior Ischemic Optic Neuropathy Compared to Open-Angle Glaucoma. ( 27603724 )
2016
48
Arteritic Anterior Ischemic Optic Neuropathy Associated with Giant Cell Arteritis in an Elderly Korean Man. ( 27247526 )
2016
49
Anterior ischemic optic neuropathy following dengue fever. ( 27843231 )
2016
50
Early applications of granulocyte colony-stimulating factor (G-CSF) can stabilize the blood-optic nerve barrier and further ameliorate optic nerve inflammation in a rat model of anterior ischemic optic neuropathy (rAION). ( 27538969 )
2016

Variations for Ischemic Optic Neuropathy

Expression for Ischemic Optic Neuropathy

Search GEO for disease gene expression data for Ischemic Optic Neuropathy.

Pathways for Ischemic Optic Neuropathy

Pathways related to Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.35 GP1BA NOS3
2
Show member pathways
11.06 ACE NOS3
3
Show member pathways
10.58 NOS3 PDE5A
4 9.74 NOS3 PDE5A

GO Terms for Ischemic Optic Neuropathy

Biological processes related to Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 8.96 ACE NOS3
2 blood vessel remodeling GO:0001974 8.62 ACE NOS3

Molecular functions related to Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 flavin adenine dinucleotide binding GO:0050660 8.96 MTHFR NOS3
2 NADP binding GO:0050661 8.62 MTHFR NOS3

Sources for Ischemic Optic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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