MCID: JPN002
MIFTS: 54

Japanese Encephalitis malady

Categories: Rare diseases, Infectious diseases, Neuronal diseases

Aliases & Classifications for Japanese Encephalitis

About this section
Sources:
2CDC, 11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Japanese Encephalitis:

Name: Japanese Encephalitis 11 47 53 2 13 67
Je 47 2
Japanese B Encephalitis 11
 
Encephalitis, Japanese 38
Encephalitis Japanese 49

Characteristics:

Orphanet epidemiological data:

53
japanese encephalitis:
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:10844
ICD1029 A83.0
ICD9CM31 062.0
MeSH38 D004672
NCIt44 C34577
Orphanet53 ORPHA79139
MESH via Orphanet39 D004672
UMLS via Orphanet68 C0014057
ICD10 via Orphanet30 A83.0

Summaries for Japanese Encephalitis

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CDC:2 Japanese encephalitis (JE) virus is the leading cause of vaccine-preventable encephalitis in Asia and the western Pacific. For most travelers to Asia, the risk for JE is very low but varies based on destination, duration of travel, season, and activities. JE virus is maintained in a cycle involving mosquitoes and vertebrate hosts, mainly pigs and wading birds. Humans can be infected when bitten by an infected mosquito. Most human infections are asymptomatic or result in only mild symptoms. However, a small percentage of infected persons develop inflammation of the brain (encephalitis), with symptoms including sudden onset of headache, high fever, disorientation, coma, tremors and convulsions. About 1 in 4 cases are fatal. There is no specific treatment for JE. Patient management focuses on supportive care and management of complications. Steps to prevent JE include using personal protective measures to prevent mosquito bites and vaccination.

MalaCards based summary: Japanese Encephalitis, also known as je, is related to aseptic meningitis and west nile virus, and has symptoms including headache, high fever and neck stiffness. An important gene associated with Japanese Encephalitis is CD209 (CD209 Molecule), and among its related pathways are Cytokines and Inflammatory Response and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include brain, brain and t cells, and related mouse phenotypes are homeostasis/metabolism and hematopoietic system.

Disease Ontology:11 A viral infectious disease that results in infection located in brain, has material basis in Japanese encephalitis virus, which is transmitted by Culex tritaeniorhynchus mosquito bite. The infection has symptom headache, has symptom high fever, has symptom neck stiffness, has symptom stupor, has symptom disorientation, has symptom coma, has symptom tremors, has symptom convulsions, and has symptom spastic paralysis.

Wikipedia:70 Japanese encephalitis (JE), formerly known as Japanese B encephalitis to distinguish it from Economo\'s... more...

Related Diseases for Japanese Encephalitis

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Diseases related to Japanese Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1aseptic meningitis29.6CLEC4G, DDX58
2west nile virus29.2CD209, CLEC4M, DDX58, HELLS, TLR3
3myelitis29.0CXCL10, IFNB1, TNF
4encephalitis10.9
5humeroradioulnar synostosis10.4DDX58, IFNB1
6secretory diarrhea10.3DDX58, IFNB1
7listeriosis10.2IFNB1, TLR3
8aleutian mink disease10.2DDX58, IFNB1
9streptococcal meningitis10.2IFNB1, TNF
10mastocytosis cutaneous with short stature conductive hearing loss and microtia10.1CD209, TNF
11pancreatic solid pseudopapillary carcinoma10.0HELLS, TNF
12steatorrhea10.0CXCL10, TNF
13atypical depressive disorder10.0CXCL10, TNF
14oesophagostomiasis10.0IFNB1, TNF
15non-langerhans-cell histiocytosis10.0CD209, IFNB1, TNF
16progressive relapsing multiple sclerosis9.9CXCL10, IFNB1
17neuronitis9.9
18erythema multiforme9.9CD209, CXCL10, TLR3
19murray valley encephalitis9.9
20macular amyloidosis9.9CXCL10, TNF
21hereditary ataxia9.8CLEC4M, DDX58, TNF
22dentin dysplasia9.8CD209, CXCL10, TNF
23binocular vision disease9.8CXCL10, TNF
24dentinogenesis imperfecta9.8CD209, TLR3, TNF
25whipple disease9.8DDX58, IFNB1, TNF
26neuroblastoma9.8
27malaria9.8
28tick-borne encephalitis9.8
29endotheliitis9.8
30human monocytic ehrlichiosis9.8CCL5, CD209, DDX58
31primary orthostatic tremor9.7CCL5, TNF
32toxic maculopathy9.7CXCL10, TNF
33hereditary hemorrhagic telangiectasia9.7IFNB1, TLR3, TNF
34hypokalemia9.7CXCL10, DDX58, TNF
35intracranial hemorrhage in brain cerebrovascular malformations9.7CXCL10, IFNB1, TNF
36sterility due to immotile flagella9.7CCL5, TNF
37orbital lymphangioma9.7CCL5, TNF
38viral encephalitis9.7
39yellow fever9.7
40nervous system disease9.7CD209, DDX58, IFNB1, TLR3
41medulloblastoma9.6
42dengue hemorrhagic fever9.6
43chikungunya9.6
44filariasis9.6
45hemiplegia9.6
46rabies9.6
47cerebritis9.6
48herpes simplex9.6
49meningitis9.6
50hemorrhagic fever9.6

Graphical network of the top 20 diseases related to Japanese Encephalitis:



Diseases related to japanese encephalitis

Symptoms for Japanese Encephalitis

About this section

Symptoms:

 11 (show all 9)
  • headache
  • high fever
  • neck stiffness
  • stupor
  • disorientation
  • coma
  • tremors
  • convulsions
  • spastic paralysis

Drugs & Therapeutics for Japanese Encephalitis

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Drugs for Japanese Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EthanolapprovedPhase 4204364-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2AntibodiesPhase 4, Phase 3, Phase 2, Phase 16045
3VaccinesPhase 4, Phase 3, Phase 2, Phase 16428
4ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16045
5
Aluminum hydroxideapprovedPhase 3, Phase 120121645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
6Protective AgentsPhase 37190
7DEETPhase 32
8Insect RepellentsPhase 33
9
LactitolPhase 3332585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
10Heptavalent Pneumococcal Conjugate VaccinePhase 3454
11Pharmaceutical SolutionsPhase 37793
12
RibavirinapprovedPhase 298436791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
13
Neomycinapproved, vet_approvedPhase 1, Phase 2481404-04-28378
Synonyms:
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
11025-81-3
119-04-0
1393-86-8
1404-04-2
1405-10-3 (sulfate (salt))
4-18-00-07476 (Beilstein Handbook Reference)
72131_FLUKA
AB00443887
AC1L1QVH
Actilin
Actiline
Antibiotic 10676
Antibiotic produced by Streptomyces decaris. Neomycin B
Antibiotique
BDG-(1-4)CYY-(5-1)RIB-(3-1)IDG
BDG-(1-4)NEB-(5-1)RIB-(3-1)NED
BPBio1_000326
BRN 0101621
BSPBio_000296
C01737
C23H46N6O13
C25H50N6O13
CCRIS 5462
CHEBI:7508
CID8378
Caswell No. 595
D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy
D05140
DB00452
DB00994
EINECS 204-292-2
EINECS 215-766-3
EPA Pesticide Chemical Code 006303
Endomixin
Enterfram
Fradiomycin
Fradiomycin B
Fradiomycinum
Framicetina
Framicetina [INN-Spanish]
Framycetin
Framycetin (INN)
Framycetin [INN:BAN:DCF]
Framycetine
Framycetine [INN-French]
Framycetinum
Framycetinum [INN-Latin]
 
Framygen
Fraquinol
HMS2089P15
HSDB 3242
LS-96091
LS-96095
MolPort-003-938-736
Myacine
Myacyne
Mycifradin
Myciguent
N1142_SIGMA
NCGC00179612-01
NEOMYCIN AND POLYMYXIN B SULFATES
NEOMYCIN B
NEOMYCIN SULFATE
NMY
Neo-Fradin
Neo-Rx
Neobiotic
Neobrettin
Neolate
Neomas
Neomcin
Neomicina
Neomicina [DCIT]
Neomin
Neomycin B Sulfate
Neomycin B sulfate
Neomycin Sulfate
Neomycin Sulphate
Neomycin solution
Neomycine
Neomycine [INN-French]
Neomycinum
Neomycinum [INN-Latin]
Nivemycin
PIMAVECORT
Prestwick3_000158
ST075177
Soframycin
Soframycin Ophthalmic
Soframycine
Tuttomycin
UNII-4BOC774388
UNII-I16QD7X297
USAF CB-19
VONAMYCIN
Vonamycin powder V
neomycin
14AntimetabolitesPhase 211774
15Anti-Infective AgentsPhase 221402
16Antiviral AgentsPhase 29732
17Rho(D) Immune GlobulinPhase 2317
18gamma-GlobulinsPhase 2317
19Immunoglobulins, IntravenousPhase 2324
20Aluminum sulfatePhase 187

Interventional clinical trials:

(show top 50)    (show all 78)
idNameStatusNCT IDPhase
1Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in ChildrenUnknown statusNCT01954810Phase 4
2Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis VaccineUnknown statusNCT01398540Phase 4
3A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2CompletedNCT01656200Phase 4
4Immunogenicity of Co-administration of Measles and Japanese Encephalitis VaccinesCompletedNCT02643433Phase 4
5Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAXCompletedNCT02526550Phase 4
6This is a Study to Assess the Safety and Immunogenicity of Ixiaro® (IC51) in an Elderly PopulationCompletedNCT01158599Phase 4
7Post-licensure Safety Study of IMOJEV® in ThailandCompletedNCT01981967Phase 4
86-year Antibody Check After Third Vaccination Against Japanese EncephalitisCompletedNCT02039440Phase 4
9Lot-to-lot Consistency Trial of JE Live Attenuated SA 14-14-2 VaccineCompletedNCT01567865Phase 4
10Immunogenicity of SA 14-14-2 JE VaccineCompletedNCT01635816Phase 4
11Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE VaccineCompletedNCT01815073Phase 4
12Long-term Immunogenicity and Safety of Fourth Administration of Boryung Cell-Culture Japanese Encephalitis VaccineinjRecruitingNCT02532569Phase 4
13Postmarketing Surveillance Study for IMOJEV® in Republic of KoreaRecruitingNCT02933710Phase 4
14Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella VaccineRecruitingNCT02880865Phase 4
15Long-term Immunogenicity After Receipt of JE Vaccine and Antibody Response and Safety to a Booster DoseActive, not recruitingNCT02514746Phase 4
16Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDRUnknown statusNCT00938379Phase 3
17Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in ToddlersCompletedNCT01396512Phase 3
18A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and ToddlersCompletedNCT01092507Phase 3
19Determining Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles VaccineCompletedNCT00249769Phase 3
20Longterm Immunogenicity of the Japanese Encephalitis Vaccine IC51CompletedNCT00596102Phase 3
21Long-term Follow-up of Immunogenicity of a Single Dose of Japanese Encephalitis Chimeric Virus Vaccine in ToddlersCompletedNCT01001988Phase 3
22Study of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With JE-CVCompletedNCT01190228Phase 3
23Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese ToddlersCompletedNCT01188343Phase 3
24Live Attenuated Japanese Encephalitis (JE) Vaccine Coadministered With Measles Vaccine in Infants 9 Months of AgeCompletedNCT00463684Phase 3
25Rapid Immunization Study of the Japanese Encephalitis Vaccine IC51CompletedNCT00595790Phase 3
26Long Term Persistence and Effect of a Booster Dose of the Japanese Encephalitis Vaccine IC51CompletedNCT00595270Phase 3
27Immunogenicity Study of the Japanese Encephalitis Vaccine IC51CompletedNCT00604708Phase 3
28Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE VaccineCompletedNCT00463476Phase 3
29Ixiaro as Booster After Mouse-brain Derived Vaccines for Japanese EncephalitisCompletedNCT01386827Phase 3
30Study of a Single Primary Dose Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV®) in Healthy SubjectsCompletedNCT02492165Phase 3
31Safety and Tolerability of the Japanese Encephalitis Vaccine IC51CompletedNCT00605085Phase 3
32Determining Long-Term Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles VaccineCompletedNCT00412516Phase 3
33Study of ChimeriVax™-Japanese Encephalitis Vaccine in Toddlers in Thailand and the PhilippinesCompletedNCT00735644Phase 3
34Immunogenicity and Safety of Inactivated Vero Cell Derived Japanese Encephalitis Vaccine in Thai ChildrenCompletedNCT01408537Phase 3
35Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult SubjectsCompletedNCT01662440Phase 3
36A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAXCompletedNCT00314145Phase 3
37Comparison of Three Commercial Batches of the Japanese Encephalitis Vaccine IC51CompletedNCT00595465Phase 3
38A Clinical Trial for Inactivated Japanese Encephalitis Vaccine in Healthy Chinese InfantsCompletedNCT02367664Phase 3
39Comparison of Three Batches of the Japanese Encephalitis Vaccine IC51CompletedNCT00594958Phase 3
40Study of a Booster Dose of IMOJEV® Vaccine One Year After Primary Immunization in Healthy Children in South KoreaCompletedNCT01900444Phase 3
41Safety and Immunogenicity of the Japanese Encephalitis Vaccine IC51 (IXIARO®) in a Pediatric PopulationCompletedNCT01041573Phase 3
42Concomitant Vaccination With the Japanese Encephalitis Vaccine IC51 and HARVIX® 1440CompletedNCT00596271Phase 3
43Safety Study of ChimeriVax™-JE Vaccine to Prevent Japanese Encephalitis.CompletedNCT00314132Phase 3
44Open-label, Randomized Study in a Pediatric Population in a JEV (Japanese Encephalitis Virus)-Endemic CountryCompletedNCT01296360Phase 3
45Effect of a Booster Dose of the Japanese Encephalitis Vaccine IC51CompletedNCT00595309Phase 3
46Immunogenicity of a Commercial Batch of JEV IC51 up to 24 Months Post FillingCompletedNCT00776230Phase 3
47Immunogenicity and Safety of the Japanese Encephalitis Vaccine IC51 (IXIARO®, JESPECT®) in a Pediatric Population in Non-endemic CountriesCompletedNCT01047839Phase 3
48Clinical Trial to Assess the Immunogenicity and Safety of the Vero Cell-derived JE Vaccine in KoreaCompletedNCT01150942Phase 3
49Long Term Immunity and Safety Following Vaccination With the JEV IC51 (IXIARO®, JESPECT®) in Pediatric Population In Non Endemic Countries. Uncontrolled, Ph3 FU-StudyCompletedNCT01246479Phase 3
50A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in AdultsCompletedNCT01466387Phase 3

Search NIH Clinical Center for Japanese Encephalitis


Cochrane evidence based reviews: encephalitis, japanese

Genetic Tests for Japanese Encephalitis

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Anatomical Context for Japanese Encephalitis

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MalaCards organs/tissues related to Japanese Encephalitis:

35
Brain, T cells, B cells, Testes, Endothelial, Kidney, Monocytes

FMA organs/tissues related to Japanese Encephalitis:

17
Brain

Animal Models for Japanese Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Japanese Encephalitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.4CLEC4G, CLEC4M, CXCL10, DDX58, HELLS, IFNB1
2MP:00053976.9CCL5, CLEC4G, CLEC4M, CXCL10, DDX58, HELLS
3MP:00053876.1CCL5, CLEC4G, CLEC4M, CXCL10, DDX58, HELLS

Publications for Japanese Encephalitis

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Articles related to Japanese Encephalitis:

(show top 50)    (show all 671)
idTitleAuthorsYear
1
How Zoophilic Japanese Encephalitis Vector Mosquitoes Feed on Humans. (28082626)
2017
2
Antisense Oligonucleotides Targeting Raf-1 Block Japanese Encephalitis Virus In Vitro and In Vivo. (28051352)
2017
3
Diagnostic dilemma-dengue or Japanese encephalitis? (28084251)
2017
4
miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells. (25889446)
2015
5
The immunogenicity of tetravalent dengue DNA vaccine in mice pre-exposed to Japanese encephalitis or Dengue virus antigens. (26342114)
2015
6
Molecular epidemiology of Japanese encephalitis in northern Vietnam, 1964-2011: genotype replacement. (25889499)
2015
7
MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125. (26202983)
2015
8
Integration analysis of miRNA and mRNA expression profiles in swine testis cells infected with Japanese encephalitis virus. (25847692)
2015
9
TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. (24909816)
2014
10
Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions. (24418539)
2014
11
Cell type-dependent RNA recombination frequency in the Japanese encephalitis virus. (25165704)
2014
12
High incidence of Japanese encephalitis, southern China. (23750863)
2013
13
Recovery of a chemically synthesized Japanese encephalitis virus revealed two critical adaptive mutations in NS2B and NS4A. (24362961)
2013
14
Japanese encephalitis virus isolation from mosquitoes during an outbreak in 2011 in Alappuzha district, Kerala. (24220084)
2013
15
Molecular characterization of Japanese encephalitis viruses circulating in pigs and mosquitoes on pig farms in the Chinese province of Henan. (22945473)
2013
16
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy. (23320079)
2013
17
Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. (23055570)
2013
18
Japanese encephalitis virus infection alters both neuronal and astrocytic differentiation of neural stem/progenitor cells. (23546886)
2013
19
Innate immune mechanisms in Japanese encephalitis virus infection: effect on transcription of pattern recognition receptors in mouse neuronal cells and brain tissue. (24236856)
2013
20
Modelling the long-term persistence of neutralizing antibody in adults after one dose of live attenuated Japanese encephalitis chimeric virus vaccine. (22342547)
2012
21
Safety and immunogenicity of a freeze-dried, cell culture-derived Japanese encephalitis vaccine (Inactivated) (JEBIK(Ar)V) in children. (22841478)
2012
22
Epidemiological characteristics of Japanese encephalitis in Guizhou Province, China, 1971-2009. (22840580)
2012
23
Monoclonal antibodies against NS3 and NS5 proteins of Japanese encephalitis virus. (22509919)
2012
24
Identification and characterization of the short variable region of the Japanese encephalitis virus 3' NTR. (22057659)
2012
25
Concurrent infection of Japanese encephalitis and mixed plasmodium infection. (23560024)
2012
26
Immunogenicity of one dose of Vero cell culture-derived Japanese encephalitis (JE) vaccine in adults previously vaccinated with mouse brain-derived JE vaccine. (22406277)
2012
27
DnaJ homolog Hdj2 facilitates Japanese encephalitis virus replication. (21999493)
2011
28
Knowledge, attitudes and practices of caregivers regarding Japanese encephalitis in Shaanxi Province, China. (21288546)
2011
29
A novel mutation (S227T) in domain II of the envelope gene of Japanese encephalitis virus circulating in North India. (20727244)
2011
30
Infection of mouse bone marrow-derived dendritic cells by live attenuated Japanese encephalitis virus induces cells maturation and triggers T cells activation. (21093495)
2011
31
Neuromyelitis optica after Japanese encephalitis vaccination. (20825468)
2011
32
Simultaneous detection and differentiation of dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus by a combined reverse-transcription loop-mediated isothermal amplification assay. (21777455)
2011
33
Comparison of reverse transcription loop-mediated isothermal amplification, conventional PCR and real-time PCR assays for Japanese encephalitis virus. (21116858)
2011
34
Serosurveillance for Japanese encephalitis and West Nile viruses in resident birds in Hawai'i. (20688669)
2010
35
Glial activation involvement in neuronal death by Japanese encephalitis virus infection. (20007359)
2010
36
Evaluation of extracellular subviral particles of dengue virus type 2 and Japanese encephalitis virus produced by Spodoptera frugiperda cells for use as vaccine and diagnostic antigens. (20668137)
2010
37
Identification of a heparin binding peptide from the Japanese encephalitis virus envelope protein. (20069543)
2010
38
Japanese encephalitis virus induces matrix metalloproteinase-9 in rat brain astrocytes via NF-I_B signalling dependent on MAPKs and reactive oxygen species. (20698853)
2010
39
Needle-free jet injection of small doses of Japanese encephalitis DNA and inactivated vaccine mixture induces neutralizing antibodies in miniature pigs and protects against fetal death and mummification in pregnant sows. (20851083)
2010
40
Japanese encephalitis vaccine. Useful for selected adult travellers. (20568483)
2010
41
Field evaluation of commercial immunoglobulin M antibody capture ELISA diagnostic tests for the detection of Japanese encephalitis virus infection among encephalitis patients in Nepal. (20346721)
2010
42
ISG15 over-expression inhibits replication of the Japanese encephalitis virus in human medulloblastoma cells. (20035788)
2010
43
A new inactivated Japanese encephalitis vaccine for adult travelers. (19747666)
2009
44
Virus-specific cytolytic antibodies to nonstructural protein 1 of Japanese encephalitis virus effect reduction of virus output from infected cells. (19264772)
2009
45
Expert opinion on vaccination of travelers against Japanese encephalitis. (19930391)
2009
46
Ixiaro: a new vaccine against Japanese encephalitis. (19863241)
2009
47
Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper. (16289409)
2006
48
Cell-mediated immune responses in healthy children with a history of subclinical infection with Japanese encephalitis virus: analysis of CD4+ and CD8+ T cell target specificities by intracellular delivery of viral proteins using the human immunodeficiency virus Tat protein transduction domain. (14769905)
2004
49
Effect of cytokines on Japanese encephalitis virus production by human monocytes. (2118221)
1990
50
Studies of the morphology of Murray Valley encephalitis and Japanese encephalitis viruses growing in cultured mosquito cells. (5651024)
1968

Variations for Japanese Encephalitis

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Expression for genes affiliated with Japanese Encephalitis

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Search GEO for disease gene expression data for Japanese Encephalitis.

Pathways for genes affiliated with Japanese Encephalitis

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Pathways related to Japanese Encephalitis according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.4IFNB1, TNF
29.1CD209, IFNB1, TNF
3
Show member pathways
9.0CXCL10, IFNB1, TNF
48.9CCL5, CXCL10, TNF
58.9CCL5, CXCL10, TNF
68.9CCL5, IFNB1, TNF
78.8CD209, CLEC4M, IFNB1, TNF
8
Show member pathways
8.5CXCL10, DDX58, IFNB1, TNF
9
Show member pathways
8.3CD209, IFNB1, TLR3, TNF
108.1DDX58, IFNB1, TLR3, TNF
11
Show member pathways
7.7CCL5, CXCL10, DDX58, IFNB1, TLR3
127.6CCL5, CXCL10, DDX58, TLR3, TNF
13
Show member pathways
7.1CCL5, CXCL10, DDX58, IFNB1, TLR3, TNF
14
Show member pathways
6.5CCL5, CD209, CLEC4M, CXCL10, DDX58, IFNB1

GO Terms for genes affiliated with Japanese Encephalitis

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Biological processes related to Japanese Encephalitis according to GeneCards Suite gene sharing:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1peptide antigen transportGO:004696810.5CD209, CLEC4M
2cell-cell recognitionGO:000998810.5CD209, CLEC4M
3virion attachment to host cellGO:001906210.5CD209, CLEC4M
4modulation by virus of host morphology or physiologyGO:001904810.4CD209, CLEC4M
5antigen processing and presentationGO:001988210.4CD209, CLEC4M
6viral genome replicationGO:001907910.1CD209, CLEC4M
7positive regulation of monocyte chemotaxisGO:009002610.1CCL5, CXCL10
8positive regulation of T cell migrationGO:200040610.1CCL5, CXCL10
9positive regulation of innate immune responseGO:004508910.1CCL5, IFNB1
10response to salt stressGO:000965110.0CCL5, TNF
11protein kinase B signalingGO:004349110.0CCL5, TNF
12lipopolysaccharide-mediated signaling pathwayGO:003166310.0CCL5, TNF
13leukocyte cell-cell adhesionGO:00071599.9CCL5, CD209, CLEC4M
14positive regulation of fever generationGO:00316229.9CCL5, TNF
15positive regulation of osteoclast differentiationGO:00456729.9CCL5, TNF
16adaptive immune responseGO:00022509.9CD209, CLEC4M, IFNB1
17cellular response to dsRNAGO:00713599.9IFNB1, TLR3
18cellular response to exogenous dsRNAGO:00713609.8IFNB1, TLR3
19cellular response to interferon-betaGO:00354589.7IFNB1, TLR3
20necroptotic signaling pathwayGO:00975279.7TLR3, TNF
21positive regulation of chemokine productionGO:00327229.7TLR3, TNF
22positive regulation of chemokine biosynthetic processGO:00450809.7TLR3, TNF
23positive regulation of NF-kappaB import into nucleusGO:00423469.7TLR3, TNF
24extrinsic apoptotic signaling pathwayGO:00971919.7TLR3, TNF
25detection of virusGO:00095979.6DDX58, TLR3
26negative regulation of myoblast differentiationGO:00456629.6CXCL10, TNF
27negative regulation of viral genome replicationGO:00450719.5CCL5, IFNB1, TNF
28positive regulation of interferon-beta productionGO:00327289.5DDX58, TLR3
29viral entry into host cellGO:00467189.4CD209, CLEC4G, CLEC4M
30response to exogenous dsRNAGO:00433309.1DDX58, IFNB1, TLR3
31defense response to bacteriumGO:00427429.0IFNB1, TLR3, TNF
32defense response to virusGO:00516079.0CXCL10, IFNB1, TLR3
33positive regulation of interleukin-6 productionGO:00327559.0DDX58, TLR3, TNF
34positive regulation of interleukin-8 productionGO:00327578.8DDX58, TLR3, TNF
35innate immune responseGO:00450878.7CD209, CLEC4M, DDX58, TLR3
36inflammatory responseGO:00069548.4CCL5, CXCL10, TLR3, TNF
37positive regulation of transcription from RNA polymerase II promoterGO:00459447.6CXCL10, DDX58, IFNB1, TLR3, TNF
38response to virusGO:00096157.5CCL5, CXCL10, DDX58, IFNB1, TLR3, TNF

Molecular functions related to Japanese Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virion bindingGO:004679010.0CD209, CLEC4M
2peptide antigen bindingGO:00426059.8CD209, CLEC4M
3mannose bindingGO:00055379.6CD209, CLEC4M
4virus receptor activityGO:00016189.5CD209, CLEC4G, CLEC4M

Sources for Japanese Encephalitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet