MCID: JPN002
MIFTS: 51

Japanese Encephalitis malady

Categories: Rare diseases, Infectious diseases, Neuronal diseases

Aliases & Classifications for Japanese Encephalitis

About this section
Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 2CDC, 66UMLS, 48Novoseek, 37MeSH, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Japanese Encephalitis:

Name: Japanese Encephalitis 11 46 13 52 2 66
Je 46 2
Japanese B Encephalitis 11
 
Encephalitis, Japanese 37
Encephalitis Japanese 48

Characteristics:

Orphanet epidemiological data:

52
japanese encephalitis:
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:10844
ICD1028 A83.0
ICD9CM30 062.0
MeSH37 D004672
NCIt43 C34577
Orphanet52 ORPHA79139
ICD10 via Orphanet29 A83.0
MESH via Orphanet38 D004672
UMLS via Orphanet67 C0014057

Summaries for Japanese Encephalitis

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CDC:2 Japanese encephalitis (JE) virus is the leading cause of vaccine-preventable encephalitis in Asia and the western Pacific. For most travelers to Asia, the risk for JE is very low but varies based on destination, duration of travel, season, and activities. JE virus is maintained in a cycle involving mosquitoes and vertebrate hosts, mainly pigs and wading birds. Humans can be infected when bitten by an infected mosquito. Most human infections are asymptomatic or result in only mild symptoms. However, a small percentage of infected persons develop inflammation of the brain (encephalitis), with symptoms including sudden onset of headache, high fever, disorientation, coma, tremors and convulsions. About 1 in 4 cases are fatal. There is no specific treatment for JE. Patient management focuses on supportive care and management of complications. Steps to prevent JE include using personal protective measures to prevent mosquito bites and vaccination.

MalaCards based summary: Japanese Encephalitis, also known as je, is related to aseptic meningitis and west nile virus, and has symptoms including headache, high fever and neck stiffness. An important gene associated with Japanese Encephalitis is CD209 (CD209 Molecule), and among its related pathways are Type II interferon signaling (IFNG) and Tuberculosis. Affiliated tissues include brain, brain and t cells, and related mouse phenotypes are immune system and hematopoietic system.

Disease Ontology:11 A viral infectious disease that results in infection located in brain, has material basis in japanese encephalitis virus, which is transmitted by culex tritaeniorhynchus mosquito bite. the infection has symptom headache, has symptom high fever, has symptom neck stiffness, has symptom stupor, has symptom disorientation, has symptom coma, has symptom tremors, has symptom convulsions, and has symptom spastic paralysis.

Wikipedia:69 Japanese encephalitis (JE), formerly known as Japanese B encephalitis to distinguish it from Economo\'s... more...

Related Diseases for Japanese Encephalitis

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Diseases related to Japanese Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 75)
idRelated DiseaseScoreTop Affiliating Genes
1aseptic meningitis29.4CLEC4G, DDX58
2west nile virus28.7CD209, CLEC4M, DDX58, HELLS, TLR3
3encephalitis11.0
4non-langerhans-cell histiocytosis10.4CD209, IFNB1
5vagina leiomyoma10.3IFNB1, SOD1
6dentin dysplasia10.2CD209, CXCL10
7humeroradioulnar synostosis10.1DDX58, IFNB1
8human monocytic ehrlichiosis10.1CD209, DDX58
9secretory diarrhea10.1DDX58, IFNB1
10neuronitis10.1
11dentinogenesis imperfecta10.0CD209, TLR3
12murray valley encephalitis10.0
13progressive relapsing multiple sclerosis10.0CXCL10, IFNB1
14aleutian mink disease10.0DDX58, IFNB1
15erythema multiforme9.9CD209, CXCL10, TLR3
16urethral calculus9.9IFNB1, TYK2
17neuroblastoma9.9
18malaria9.9
19tick-borne encephalitis9.9
20endotheliitis9.9
21hypokalemia9.8CXCL10, DDX58
22listeriosis9.8IFNB1, SOD1, TLR3
23yellow fever9.8
24inner ear disease9.8CD209, CLEC4M, CXCL10, IFNB1
25medulloblastoma9.7
26dengue hemorrhagic fever9.7
27chikungunya9.7
28filariasis9.7
29hemiplegia9.7
30rabies9.7
31myelitis9.7
32cerebritis9.7
33herpes simplex9.7
34meningitis9.7
35hemorrhagic fever9.7
36herpes simplex encephalitis9.7
37transverse myelitis9.7
38encephalopathy9.7
39acute transverse myelitis9.7
40chlamydia9.6CXCL10, TLR3
41hepatitis c virus9.6
42hepatitis9.6
43hydrocephalus9.6
44neuromyelitis optica9.6
45thrombocytopenia9.6
46apraxia9.6
47western equine encephalitis9.6
48st. louis encephalitis9.6
49tetanus9.6
50rift valley fever9.6

Graphical network of the top 20 diseases related to Japanese Encephalitis:



Diseases related to japanese encephalitis

Symptoms for Japanese Encephalitis

About this section

Symptoms:

 11 (show all 9)
  • headache
  • high fever
  • neck stiffness
  • stupor
  • disorientation
  • coma
  • tremors
  • convulsions
  • spastic paralysis

Drugs & Therapeutics for Japanese Encephalitis

About this section

Drugs for Japanese Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EthanolPhase 4197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2
Aluminum hydroxidePhase 319421645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
3
lactitolPhase 3325585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
4
NeomycinPhase 1, Phase 2471404-04-28378
Synonyms:
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
11025-81-3
119-04-0
1393-86-8
1404-04-2
1405-10-3 (sulfate (salt))
4-18-00-07476 (Beilstein Handbook Reference)
72131_FLUKA
AB00443887
AC1L1QVH
Actilin
Actiline
Antibiotic 10676
Antibiotic produced by Streptomyces decaris. Neomycin B
Antibiotique
BDG-(1-4)CYY-(5-1)RIB-(3-1)IDG
BDG-(1-4)NEB-(5-1)RIB-(3-1)NED
BPBio1_000326
BRN 0101621
BSPBio_000296
C01737
C23H46N6O13
C25H50N6O13
CCRIS 5462
CHEBI:7508
CID8378
Caswell No. 595
D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy
D05140
DB00452
DB00994
EINECS 204-292-2
EINECS 215-766-3
EPA Pesticide Chemical Code 006303
Endomixin
Enterfram
Fradiomycin
Fradiomycin B
Fradiomycinum
Framicetina
Framicetina [INN-Spanish]
Framycetin
Framycetin (INN)
Framycetin [INN:BAN:DCF]
Framycetine
Framycetine [INN-French]
Framycetinum
Framycetinum [INN-Latin]
 
Framygen
Fraquinol
HMS2089P15
HSDB 3242
LS-96091
LS-96095
MolPort-003-938-736
Myacine
Myacyne
Mycifradin
Myciguent
N1142_SIGMA
NCGC00179612-01
NEOMYCIN AND POLYMYXIN B SULFATES
NEOMYCIN B
NEOMYCIN SULFATE
NMY
Neo-Fradin
Neo-Rx
Neobiotic
Neobrettin
Neolate
Neomas
Neomcin
Neomicina
Neomicina [DCIT]
Neomin
Neomycin B Sulfate
Neomycin B sulfate
Neomycin Sulfate
Neomycin Sulphate
Neomycin solution
Neomycine
Neomycine [INN-French]
Neomycinum
Neomycinum [INN-Latin]
Nivemycin
PIMAVECORT
Prestwick3_000158
ST075177
Soframycin
Soframycin Ophthalmic
Soframycine
Tuttomycin
UNII-4BOC774388
UNII-I16QD7X297
USAF CB-19
VONAMYCIN
Vonamycin powder V
neomycin
5
RibavirinPhase 296836791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin

Interventional clinical trials:

(show top 50)    (show all 76)
idNameStatusNCT IDPhase
1A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2CompletedNCT01656200Phase 4
2Immunogenicity of Co-administration of Measles and Japanese Encephalitis VaccinesCompletedNCT02643433Phase 4
3This is a Study to Assess the Safety and Immunogenicity of Ixiaro® (IC51) in an Elderly PopulationCompletedNCT01158599Phase 4
4Post-licensure Safety Study of IMOJEV® in ThailandCompletedNCT01981967Phase 4
5Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAXCompletedNCT02526550Phase 4
66-year Antibody Check After Third Vaccination Against Japanese EncephalitisCompletedNCT02039440Phase 4
7Lot-to-lot Consistency Trial of JE Live Attenuated SA 14-14-2 VaccineCompletedNCT01567865Phase 4
8Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE VaccineCompletedNCT01815073Phase 4
9Immunogenicity of SA 14-14-2 JE VaccineCompletedNCT01635816Phase 4
10Long-term Immunogenicity and Safety of Fourth Administration of Boryung Cell-Culture Japanese Encephalitis VaccineinjRecruitingNCT02532569Phase 4
11Long-term Immunogenicity After Receipt of JE Vaccine and Antibody Response and Safety to a Booster DoseActive, not recruitingNCT02514746Phase 4
12Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis VaccineEnrolling by invitationNCT01398540Phase 4
13Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella VaccineNot yet recruitingNCT02880865Phase 4
14Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in ChildrenNot yet recruitingNCT01954810Phase 4
15Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in ToddlersCompletedNCT01396512Phase 3
16A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and ToddlersCompletedNCT01092507Phase 3
17Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese ToddlersCompletedNCT01188343Phase 3
18Study of ChimeriVax™-Japanese Encephalitis Vaccine in Toddlers in Thailand and the PhilippinesCompletedNCT00735644Phase 3
19Study of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With JE-CVCompletedNCT01190228Phase 3
20Determining Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles VaccineCompletedNCT00249769Phase 3
21Long-term Follow-up of Immunogenicity of a Single Dose of Japanese Encephalitis Chimeric Virus Vaccine in ToddlersCompletedNCT01001988Phase 3
22Determining Long-Term Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles VaccineCompletedNCT00412516Phase 3
23A Clinical Trial for Inactivated Japanese Encephalitis Vaccine in Healthy Chinese InfantsCompletedNCT02367664Phase 3
24Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult SubjectsCompletedNCT01662440Phase 3
25A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in AdultsCompletedNCT01466387Phase 3
26Study of a Single Primary Dose Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV®) in Healthy SubjectsCompletedNCT02492165Phase 3
27Ixiaro as Booster After Mouse-brain Derived Vaccines for Japanese EncephalitisCompletedNCT01386827Phase 3
28Longterm Immunogenicity of the Japanese Encephalitis Vaccine IC51CompletedNCT00596102Phase 3
29Safety and Immunogenicity of the Japanese Encephalitis Vaccine IC51 (IXIARO®) in a Pediatric PopulationCompletedNCT01041573Phase 3
30Live Attenuated Japanese Encephalitis (JE) Vaccine Coadministered With Measles Vaccine in Infants 9 Months of AgeCompletedNCT00463684Phase 3
31Immunogenicity and Safety of Inactivated Vero Cell Derived Japanese Encephalitis Vaccine in Thai ChildrenCompletedNCT01408537Phase 3
32Safety and Tolerability of the Japanese Encephalitis Vaccine IC51CompletedNCT00605085Phase 3
33Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE VaccineCompletedNCT00463476Phase 3
34Rapid Immunization Study of the Japanese Encephalitis Vaccine IC51CompletedNCT00595790Phase 3
35Long Term Persistence and Effect of a Booster Dose of the Japanese Encephalitis Vaccine IC51CompletedNCT00595270Phase 3
36Immunogenicity Study of the Japanese Encephalitis Vaccine IC51CompletedNCT00604708Phase 3
37A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAXCompletedNCT00314145Phase 3
38Study of a Booster Dose of IMOJEV® Vaccine One Year After Primary Immunization in Healthy Children in South KoreaCompletedNCT01900444Phase 3
39Safety Study of ChimeriVax™-JE Vaccine to Prevent Japanese Encephalitis.CompletedNCT00314132Phase 3
40Open-label, Randomized Study in a Pediatric Population in a JEV (Japanese Encephalitis Virus)-Endemic CountryCompletedNCT01296360Phase 3
41Comparison of Three Commercial Batches of the Japanese Encephalitis Vaccine IC51CompletedNCT00595465Phase 3
42Comparison of Three Batches of the Japanese Encephalitis Vaccine IC51CompletedNCT00594958Phase 3
43Concomitant Vaccination With the Japanese Encephalitis Vaccine IC51 and HARVIX® 1440CompletedNCT00596271Phase 3
44Effect of a Booster Dose of the Japanese Encephalitis Vaccine IC51CompletedNCT00595309Phase 3
45Immunogenicity of a Commercial Batch of JEV IC51 up to 24 Months Post FillingCompletedNCT00776230Phase 3
46Immunogenicity and Safety of the Japanese Encephalitis Vaccine IC51 (IXIARO®, JESPECT®) in a Pediatric Population in Non-endemic CountriesCompletedNCT01047839Phase 3
47Long Term Immunity and Safety Following Vaccination With the JEV IC51 (IXIARO®, JESPECT®) in Pediatric Population In Non Endemic Countries. Uncontrolled, Ph3 FU-StudyCompletedNCT01246479Phase 3
48Clinical Trial to Assess the Immunogenicity and Safety of the Vero Cell-derived JE Vaccine in KoreaCompletedNCT01150942Phase 3
49Novartis Vaccine and Diagnostics Carriage TrialCompletedNCT01214850Phase 3
50Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDRRecruitingNCT00938379Phase 3

Search NIH Clinical Center for Japanese Encephalitis


Cochrane evidence based reviews: encephalitis, japanese

Genetic Tests for Japanese Encephalitis

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Anatomical Context for Japanese Encephalitis

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MalaCards organs/tissues related to Japanese Encephalitis:

34
Brain, T cells, B cells, Testes, Endothelial, Kidney, Monocytes

FMA organs/tissues related to Japanese Encephalitis:

17
Brain

Animal Models for Japanese Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Japanese Encephalitis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053876.3CLEC4G, CLEC4M, CXCL10, DDX58, HELLS, IFNB1
2MP:00053976.1CLEC4G, CLEC4M, CXCL10, DDX58, HELLS, IFNB1
3MP:00053766.1CLEC4G, CLEC4M, CXCL10, DDX58, HELLS, IFNB1

Publications for Japanese Encephalitis

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Articles related to Japanese Encephalitis:

(show top 50)    (show all 650)
idTitleAuthorsYear
1
miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells. (25889446)
2015
2
The immunogenicity of tetravalent dengue DNA vaccine in mice pre-exposed to Japanese encephalitis or Dengue virus antigens. (26342114)
2015
3
Molecular epidemiology of Japanese encephalitis in northern Vietnam, 1964-2011: genotype replacement. (25889499)
2015
4
MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125. (26202983)
2015
5
Integration analysis of miRNA and mRNA expression profiles in swine testis cells infected with Japanese encephalitis virus. (25847692)
2015
6
TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. (24909816)
2014
7
Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions. (24418539)
2014
8
Cell type-dependent RNA recombination frequency in the Japanese encephalitis virus. (25165704)
2014
9
High incidence of Japanese encephalitis, southern China. (23750863)
2013
10
Recovery of a chemically synthesized Japanese encephalitis virus revealed two critical adaptive mutations in NS2B and NS4A. (24362961)
2013
11
Japanese encephalitis virus isolation from mosquitoes during an outbreak in 2011 in Alappuzha district, Kerala. (24220084)
2013
12
Molecular characterization of Japanese encephalitis viruses circulating in pigs and mosquitoes on pig farms in the Chinese province of Henan. (22945473)
2013
13
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy. (23320079)
2013
14
Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. (23055570)
2013
15
Japanese encephalitis virus infection alters both neuronal and astrocytic differentiation of neural stem/progenitor cells. (23546886)
2013
16
Innate immune mechanisms in Japanese encephalitis virus infection: effect on transcription of pattern recognition receptors in mouse neuronal cells and brain tissue. (24236856)
2013
17
Japanese encephalitis virus non-coding RNA inhibits activation of interferon by blocking nuclear translocation of interferon regulatory factor 3. (23755934)
2013
18
Modelling the long-term persistence of neutralizing antibody in adults after one dose of live attenuated Japanese encephalitis chimeric virus vaccine. (22342547)
2012
19
Safety and immunogenicity of a freeze-dried, cell culture-derived Japanese encephalitis vaccine (Inactivated) (JEBIK(Ar)V) in children. (22841478)
2012
20
Epidemiological characteristics of Japanese encephalitis in Guizhou Province, China, 1971-2009. (22840580)
2012
21
Monoclonal antibodies against NS3 and NS5 proteins of Japanese encephalitis virus. (22509919)
2012
22
Identification and characterization of the short variable region of the Japanese encephalitis virus 3' NTR. (22057659)
2012
23
Concurrent infection of Japanese encephalitis and mixed plasmodium infection. (23560024)
2012
24
Immunogenicity of one dose of Vero cell culture-derived Japanese encephalitis (JE) vaccine in adults previously vaccinated with mouse brain-derived JE vaccine. (22406277)
2012
25
DnaJ homolog Hdj2 facilitates Japanese encephalitis virus replication. (21999493)
2011
26
Knowledge, attitudes and practices of caregivers regarding Japanese encephalitis in Shaanxi Province, China. (21288546)
2011
27
A novel mutation (S227T) in domain II of the envelope gene of Japanese encephalitis virus circulating in North India. (20727244)
2011
28
Infection of mouse bone marrow-derived dendritic cells by live attenuated Japanese encephalitis virus induces cells maturation and triggers T cells activation. (21093495)
2011
29
Neuromyelitis optica after Japanese encephalitis vaccination. (20825468)
2011
30
Simultaneous detection and differentiation of dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus by a combined reverse-transcription loop-mediated isothermal amplification assay. (21777455)
2011
31
Comparison of reverse transcription loop-mediated isothermal amplification, conventional PCR and real-time PCR assays for Japanese encephalitis virus. (21116858)
2011
32
Genetic characterization of Japanese encephalitis virus genotype II strains isolated from 1951 to 1978. (21123550)
2011
33
Serosurveillance for Japanese encephalitis and West Nile viruses in resident birds in Hawai'i. (20688669)
2010
34
Glial activation involvement in neuronal death by Japanese encephalitis virus infection. (20007359)
2010
35
Evaluation of extracellular subviral particles of dengue virus type 2 and Japanese encephalitis virus produced by Spodoptera frugiperda cells for use as vaccine and diagnostic antigens. (20668137)
2010
36
Identification of a heparin binding peptide from the Japanese encephalitis virus envelope protein. (20069543)
2010
37
Japanese encephalitis virus induces matrix metalloproteinase-9 in rat brain astrocytes via NF-I_B signalling dependent on MAPKs and reactive oxygen species. (20698853)
2010
38
Needle-free jet injection of small doses of Japanese encephalitis DNA and inactivated vaccine mixture induces neutralizing antibodies in miniature pigs and protects against fetal death and mummification in pregnant sows. (20851083)
2010
39
Japanese encephalitis vaccine. Useful for selected adult travellers. (20568483)
2010
40
Field evaluation of commercial immunoglobulin M antibody capture ELISA diagnostic tests for the detection of Japanese encephalitis virus infection among encephalitis patients in Nepal. (20346721)
2010
41
ISG15 over-expression inhibits replication of the Japanese encephalitis virus in human medulloblastoma cells. (20035788)
2010
42
NS1' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness. (19906906)
2010
43
A new inactivated Japanese encephalitis vaccine for adult travelers. (19747666)
2009
44
Virus-specific cytolytic antibodies to nonstructural protein 1 of Japanese encephalitis virus effect reduction of virus output from infected cells. (19264772)
2009
45
Expert opinion on vaccination of travelers against Japanese encephalitis. (19930391)
2009
46
Ixiaro: a new vaccine against Japanese encephalitis. (19863241)
2009
47
Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper. (16289409)
2006
48
Cell-mediated immune responses in healthy children with a history of subclinical infection with Japanese encephalitis virus: analysis of CD4+ and CD8+ T cell target specificities by intracellular delivery of viral proteins using the human immunodeficiency virus Tat protein transduction domain. (14769905)
2004
49
Effect of cytokines on Japanese encephalitis virus production by human monocytes. (2118221)
1990
50
Studies of the morphology of Murray Valley encephalitis and Japanese encephalitis viruses growing in cultured mosquito cells. (5651024)
1968

Variations for Japanese Encephalitis

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Expression for genes affiliated with Japanese Encephalitis

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Search GEO for disease gene expression data for Japanese Encephalitis.

Pathways for genes affiliated with Japanese Encephalitis

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Pathways related to Japanese Encephalitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6CXCL10, IFNB1
29.3CD209, CLEC4M, IFNB1
3
Show member pathways
9.1DDX58, TYK2
4
Show member pathways
8.8CXCL10, DDX58, IFNB1
5
Show member pathways
8.6DDX58, IFNB1, TYK2
6
Show member pathways
8.3CXCL10, DDX58, IFNB1, TLR3
7
Show member pathways
8.3CXCL10, DDX58, IFNB1, TLR3
88.3CXCL10, DDX58, TLR3, TYK2
98.2DDX58, IFNB1, TLR3, TYK2
10
Show member pathways
7.2CD209, CLEC4M, CXCL10, DDX58, IFNB1, TLR3

GO Terms for genes affiliated with Japanese Encephalitis

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Biological processes related to Japanese Encephalitis according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1peptide antigen transportGO:004696810.4CD209, CLEC4M
2intracellular transport of virusGO:007573310.4CD209, CLEC4M
3cell-cell recognitionGO:000998810.4CD209, CLEC4M
4virion attachment to host cellGO:001906210.4CD209, CLEC4M
5leukocyte cell-cell adhesionGO:000715910.4CD209, CLEC4M
6modulation by virus of host morphology or physiologyGO:001904810.4CD209, CLEC4M
7antigen processing and presentationGO:001988210.4CD209, CLEC4M
8regulation of protein kinase activityGO:004585910.2CXCL10, SOD1
9cellular response to dsRNAGO:007135910.1IFNB1, TLR3
10viral genome replicationGO:001907910.1CD209, CLEC4M
11cellular response to exogenous dsRNAGO:007136010.0IFNB1, TLR3
12regulation of type I interferon-mediated signaling pathwayGO:006033810.0IFNB1, TYK2
13cellular response to interferon-betaGO:00354589.9IFNB1, TLR3
14adaptive immune responseGO:00022509.7CD209, CLEC4M, IFNB1
15viral entry into host cellGO:00467189.5CD209, CLEC4G, CLEC4M
16detection of virusGO:00095979.5DDX58, TLR3
17positive regulation of interleukin-8 productionGO:00327579.4DDX58, TLR3
18positive regulation of interleukin-6 productionGO:00327559.4DDX58, TLR3
19positive regulation of interferon-beta productionGO:00327289.3DDX58, TLR3
20defense response to virusGO:00516078.8CXCL10, IFNB1, TLR3
21response to exogenous dsRNAGO:00433308.6DDX58, IFNB1, TLR3
22response to virusGO:00096158.3CXCL10, DDX58, IFNB1, TLR3
23innate immune responseGO:00450878.1CD209, CLEC4M, DDX58, TLR3, TYK2

Molecular functions related to Japanese Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virion bindingGO:004679010.2CD209, CLEC4M
2peptide antigen bindingGO:004260510.1CD209, CLEC4M
3mannose bindingGO:00055379.9CD209, CLEC4M
4virus receptor activityGO:00016189.2CD209, CLEC4G, CLEC4M
5double-stranded RNA bindingGO:00037259.2DDX58, TLR3
6helicase activityGO:00043868.9DDX58, HELLS

Sources for Japanese Encephalitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet