MCID: JPN001
MIFTS: 28

Japanese Spotted Fever malady

Infectious diseases category
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Summaries for Japanese Spotted Fever

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8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 A spotted fever that has material basis in rickettsia japonica, which is transmitted by ticks (dermacentor taiwanensis and haemaphysalis flava). the infection has symptom fever, has symptom eschars, has symptom regional adenopathy, and has symptom rash on extremities.

MalaCards: Japanese Spotted Fever, also known as rickettsia japonica spotted fever, is related to spotted fever and scrub typhus, and has symptoms including fever, regional adenopathy and eschars. An important gene associated with Japanese Spotted Fever is CHKB (choline kinase beta), and among its related pathways is Metabolism. Affiliated tissues include testes and skin, and related mouse phenotypes are nervous system and muscle.

Wikipedia:65 Japanese spotted fever (or oriental spotted fever) is a condition characterized by a rash that has early... more...

Aliases & Classifications for Japanese Spotted Fever

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8Disease Ontology, 10DISEASES
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

japanese spotted fever 8 10
rickettsia japonica spotted fever 8
oriental spotted fever 8


External Ids:

Disease Ontology8 DOID:0050050

Related Diseases for Japanese Spotted Fever

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17GeneCards, 18GeneDecks
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Diseases related to Japanese Spotted Fever via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1spotted fever10.9
2scrub typhus10.3
3typhus10.3
4meningoencephalitis10.2
5lyme disease10.2
6q fever10.2
7acute myocarditis10.2
8hepatitis10.2
9myocarditis10.2
10tularemia10.2

Graphical network of diseases related to Japanese Spotted Fever:



Diseases related to japanese spotted fever

Symptoms for Japanese Spotted Fever

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8Disease Ontology
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Symptoms:

8
  • fever
  • regional adenopathy
  • eschars
  • rash on extremities

Drugs & Therapeutics for Japanese Spotted Fever

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Japanese Spotted Fever

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Anatomical Context for Japanese Spotted Fever

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33MalaCards
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MalaCards organs/tissues related to Japanese Spotted Fever:

33
Testes, Skin

Animal Models for Japanese Spotted Fever or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Japanese Spotted Fever:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.1CHKB, YAP1
2MP:00053699.0CHKB, YAP1
3MP:00053868.8CHKB, YAP1

Publications for Japanese Spotted Fever

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52PubMed
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Articles related to Japanese Spotted Fever:

(show all 29)
idTitleAuthorsYear
1
A neonatal case of Japanese spotted fever. (23743544)
2013
2
A case of Japanese spotted fever complicated with central nervous system involvement and multiple organ failure. (22466839)
2012
3
Histopathological diagnosis of Japanese spotted fever using formalin-fixed, paraffin-embedded skin biopsy specimens: usefulness of immunohistochemistry and real-time PCR analysis. (21668575)
2012
4
Predictive values of clinical parameters for severe Japanese spotted fever. (20827564)
2011
5
Serological survey of five zoonoses, scrub typhus, Japanese spotted fever, tularemia, Lyme disease, and Q fever, in feral raccoons (Procyon lotor) in Japan. (20553108)
2011
6
Japanese spotted fever with acute hepatic failure: was it associated with Epstein-Barr virus? (21091673)
2010
7
Surveillance, recognition, and reporting of Tsutsugamushi disease (scrub typhus) and Japanese spotted fever by general practice clinics in Miyazaki Prefecture, determined by questionnaire survey in 2007. (19688250)
2009
8
A case of Japanese spotted fever complicated with acute myocarditis. (17314430)
2007
9
The first fatal case of Japanese spotted fever confirmed by serological and microbiological tests in Awaji Island, Japan. (17642547)
2007
10
Epidemiological study of Japanese spotted fever and tsutsugamushi disease in Shimane Prefecture, Japan. (16785708)
2006
11
Japanese spotted fever, South Korea. (16836831)
2006
12
Simultaneous development of Japanese spotted fever in a married couple in Kagoshima Prefecture. (16922489)
2006
13
Epidemiology of tsutsugamushi disease and Japanese spotted fever in Kagoshima Prefecture, Japan. (16936351)
2006
14
Severe Japanese spotted fever successfully treated with fluoroquinolone. (17170509)
2006
15
Japanese spotted fever in Korea. (16082011)
2005
16
Clinical study of Japanese spotted fever and its aggravating factors. (12673413)
2003
17
Fulminant Japanese spotted fever definitively diagnosed by the polymerase chain reaction method. (12373493)
2002
18
Japanese spotted fever involving the central nervous system: two case reports and a literature review. (12354906)
2002
19
Fulminant Japanese spotted fever associated with hypercytokinemia. (11376087)
2001
20
Japanese spotted fever associated with multiorgan failure. (11810592)
2001
21
A patient with Japanese spotted fever complicated by meningoencephalitis. (11605191)
2001
22
Outbreak of Japanese spotted fever in the southeastern part of Awaji Island. (10783585)
2000
23
Japanese spotted fever cases in Kochi prefecture. (10777859)
2000
24
Japanese spotted fever in Shimane Prefecture - outbreak and place of infection. (10871919)
2000
25
The first reported case of Japanese spotted fever in Hiroshima Prefecture, Japan. (11135712)
2000
26
Japanese spotted fever: report of 31 cases and review of the literature. (9204291)
1997
27
First isolation of a rickettsia closely related to Japanese spotted fever pathogen from a tick in Japan. (8189407)
1994
28
Gelatin particle agglutination test for early serodiagnosis of Japanese spotted fever. (1603001)
1992
29
Serological studies of antigenic similarity between Japanese spotted fever rickettsiae and Weil-Felix test antigens. (1383270)
1992

Variations for Japanese Spotted Fever

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Expression for genes affiliated with Japanese Spotted Fever

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Japanese Spotted Fever

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Pathways for genes affiliated with Japanese Spotted Fever

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50PathCards, 55Reactome, 30KEGG
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Pathways related to Japanese Spotted Fever according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1CHKB, YAP1

Compounds for genes affiliated with Japanese Spotted Fever

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GO Terms for genes affiliated with Japanese Spotted Fever

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16Gene Ontology
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Cellular components related to Japanese Spotted Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:0058299.1CHKB, YAP1

Products for genes affiliated with Japanese Spotted Fever

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Japanese Spotted Fever

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet