MCID: JJN003
MIFTS: 22

Jejunal Cancer malady

Cancer category

Summaries for Jejunal Cancer

Sources:
33MalaCards
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MalaCards: Jejunal Cancer, also known as malignant neoplasm of jejunum, is related to familial adenomatous polyposis and adenoma. An important gene associated with Jejunal Cancer is CDX2 (caudal type homeobox 2), and among its related pathways is Wnt / Hedgehog / Notch. The compounds 5-aza-2deoxycytidine and vitamin d have been mentioned in the context of this disorder.

Aliases & Classifications for Jejunal Cancer

Sources:
8Disease Ontology, 61UMLS, 27ICD9CM, 35MeSH, 57SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

jejunal cancer 8
malignant neoplasm of jejunum 8 61
malignant tumor of jejunum 8


External Ids:

Disease Ontology8 DOID:13499
ICD9CM27 152.1
SNOMED-CT57 363404008, 93846004
MeSH35 D007580
ICD1025 C17.1

Related Diseases for Jejunal Cancer

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Jejunal Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1familial adenomatous polyposis30.3CDX2, APC
2adenoma10.2
3desmoid tumor10.0
4pituitary adenoma10.0APC
5pseudomyxoma peritonei10.0CDX2
6herpes simplex10.0CDX2
7barrett's esophagus10.0APC, CDX2
8gastric adenocarcinoma10.0CDX2, APC
9gallbladder cancer10.0CDX2, APC
10stomach cancer10.0APC, CDX2
11colorectal cancer10.0CDX2, APC
12colon cancer10.0CDX2, APC
13non-small cell lung carcinoma10.0CDX2, APC

Graphical network of diseases related to Jejunal Cancer:



Diseases related to jejunal cancer

Clinical Features for Jejunal Cancer

Drugs & Therapeutics for Jejunal Cancer

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Jejunal Cancer

Drug clinical trials:

Search ClinicalTrials for Jejunal Cancer

Search NIH Clinical Center for Jejunal Cancer

Search CenterWatch for Jejunal Cancer

Genetic Tests for Jejunal Cancer

Anatomical Context for Jejunal Cancer

Animal Models for Jejunal Cancer or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Jejunal Cancer

Sources:
51PubMed
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Articles related to Jejunal Cancer:

(show all 19)
idTitleAuthorsYear
1
A two-stage operation for thoracic esophageal cancer: esophagectomy and subsequent reconstruction by a free jejunal flap. (24292600)
2014
2
Feasibility and functional efficacy of distal gastrectomy with jejunal interposition for gastric cancer: A case series. (24200755)
2014
3
Naso-gastric or naso-jejunal decompression after partial distal gastrectomy for gastric cancer. Final results of a multicenter prospective randomized trial. (24292257)
2013
4
Primary jejunal adenocarcinoma incidentally diagnosed on positron emission tomography/computed tomography in a patient with metastatic colorectal cancer: suspicion of Lynch syndrome and effect on therapeutic management. (23341528)
2013
5
Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations. (22886683)
2012
6
Response to jejunal cancer in patients with familial adenomatous polyposis. (21182984)
2011
7
Jejunal cancer in patients with familial adenomatous polyposis. (20399906)
2010
8
Jejunal cancer in patients with familial adenomatous polyposis. (20621624)
2010
9
Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case. (21046510)
2010
10
Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. (19404084)
2009
11
A case of primary jejunal cancer diagnosed by preoperative small intestinal endoscopy. (21318964)
2008
12
Education and imaging. Gastrointestinal: metallic stent for an obstructing jejunal cancer. (17074030)
2006
13
Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation. (15816449)
2005
14
Primary jejunal cancer. (16246696)
2005
15
Studies on gastrointestinal hormone and jejunal interdigestive migrating motor complex in patients with or without early dumping syndrome after total gastrectomy with Roux-en-Y reconstruction for early gastric cancer. (12657389)
2003
16
A case of jejunal intussusception with gastrointestinal bleeding caused by metastatic testicular germ cell cancer. (10567810)
1999
17
Muir-Torre syndrome: case report of a patient with concurrent jejunal and ureteral cancer and a review of the literature. (10534628)
1999
18
Two sisters with coeliac disease and jejunal cancer: just a coincidence? (8446219)
1993
19
Jejunal cancer; a case report. (20992565)
1946

Genetic Variations for Jejunal Cancer

Expression for genes affiliated with Jejunal Cancer

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Jejunal Cancer

Search GEO for disease gene expression data for Jejunal Cancer.

Pathways for genes affiliated with Jejunal Cancer

Sources:
4Cell Signaling Technology
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Pathways related to Jejunal Cancer according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1CDX2, APC

Compounds for genes affiliated with Jejunal Cancer

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Jejunal Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
15-aza-2deoxycytidine459.2APC, CDX2
2vitamin d459.2APC, CDX2
3paraffin459.1APC, CDX2
4oligonucleotide459.1APC, CDX2
5fatty acid459.0APC, CDX2
6progesterone45 60 29 11 2412.8APC, CDX2

GO Terms for genes affiliated with Jejunal Cancer

Sources:
16Gene Ontology
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Biological processes related to Jejunal Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1anterior/posterior pattern specificationGO:0099529.1CDX2, APC
2somatic stem cell maintenanceGO:0350198.8CDX2, APC

Products for genes affiliated with Jejunal Cancer

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Jejunal Cancer

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet