MCID: JJN003
MIFTS: 30

Jejunal Cancer

Categories: Cancer diseases

Aliases & Classifications for Jejunal Cancer

MalaCards integrated aliases for Jejunal Cancer:

Name: Jejunal Cancer 12 14
Malignant Neoplasm of Jejunum 12 69
Jejunal Neoplasms 41 69
Jejunal Neoplasm 12 14
Malignant Tumor of Jejunum 12
Neoplasm of Jejunum 12
Tumor of Jejunum 12
Jejunal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13499 DOID:3218
ICD10 32 C17.1
ICD9CM 34 152.1
MeSH 41 D007580
NCIt 46 C8401

Summaries for Jejunal Cancer

MalaCards based summary : Jejunal Cancer, also known as malignant neoplasm of jejunum, is related to jejunal adenocarcinoma and cribriform carcinoma. An important gene associated with Jejunal Cancer is KRT7 (Keratin 7). The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include small intestine, liver and skin, and related phenotype is cellular.

Related Diseases for Jejunal Cancer

Diseases related to Jejunal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 jejunal adenocarcinoma 11.0
2 cribriform carcinoma 10.2 KIT KRT7
3 malignant mixed mullerian tumor 10.2 KIT KRT7
4 adenoid basal cell carcinoma 10.2 KIT KRT7
5 intratubular embryonal carcinoma 10.2 KIT KRT7
6 malignant leydig cell tumor 10.1 KIT KRT7
7 warthin tumor 10.1 KIT KRT7
8 pleomorphic carcinoma 10.1 KIT KRT7
9 kidney benign neoplasm 10.1 KIT KRT7
10 dermoid cyst 10.1 KIT KRT7
11 mixed cell type cancer 10.1 KIT KRT7
12 necrotizing sialometaplasia 10.1 KIT KRT7
13 large cell neuroendocrine carcinoma 10.1 KIT KRT7
14 spindle cell synovial sarcoma 10.1 KIT KRT7
15 renal oncocytoma 10.1 KIT KRT7
16 ovarian brenner tumor 10.1 KIT KRT7
17 renal cell carcinoma, papillary, 1 10.1 KIT KRT7
18 organ system benign neoplasm 10.1 KIT KRT7
19 integumentary system cancer 10.1 KIT KRT7
20 small cell carcinoma 10.1 KIT KRT7
21 oncocytoma 10.1 KIT KRT7
22 chromophobe renal cell carcinoma 10.1 KIT KRT7
23 merkel cell carcinoma 10.0 KIT KRT7
24 thymus cancer 10.0 KIT KRT7
25 teratoma 10.0 KIT KRT7
26 sarcoma, synovial 10.0 KIT KRT7
27 cecal benign neoplasm 9.9 KRT7 MUTYH
28 duodenum cancer 9.9 KRT7 MUTYH
29 cell type cancer 9.9 KIT KRT7
30 familial adenomatous polyposis 9.9
31 cell type benign neoplasm 9.8 KRT7 MUTYH
32 small cell cancer of the lung 9.8 KIT KRT7
33 rectal neoplasm 9.7 KRT7 MUTYH
34 gastrointestinal stromal tumor 9.7
35 angiodysplasia 9.7
36 smooth muscle tumor 9.7
37 intestinal obstruction 9.7
38 autosomal genetic disease 9.6 MUTYH WRN
39 esophagitis 9.6
40 lynch syndrome 9.6
41 desmoid tumor 9.6
42 squamous cell carcinoma 9.6
43 intestinal perforation 9.6
44 gastrointestinal system benign neoplasm 9.6 KIT KRT7 MUTYH
45 gastrointestinal system cancer 9.6 KIT KRT7 MUTYH
46 adenoma 9.4 KRT7 MUTYH
47 endometrial cancer 9.3 KIT KRT7 MUTYH

Comorbidity relations with Jejunal Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Intestinal Obstruction

Graphical network of the top 20 diseases related to Jejunal Cancer:



Diseases related to Jejunal Cancer

Symptoms & Phenotypes for Jejunal Cancer

MGI Mouse Phenotypes related to Jejunal Cancer:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 GAN KIT KRT7 MUTYH WRN

Drugs & Therapeutics for Jejunal Cancer

Drugs for Jejunal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Cola Nutraceutical Phase 1
3
Menthol Approved 2216-51-5 16666
4 Fluorodeoxyglucose F18
5 Antibodies
6 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science Recruiting NCT03189992 Phase 1 Bushen-Jianpi Dedoction;cinobufotalin injection
2 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
3 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132

Search NIH Clinical Center for Jejunal Cancer

Cochrane evidence based reviews: jejunal neoplasms

Genetic Tests for Jejunal Cancer

Anatomical Context for Jejunal Cancer

MalaCards organs/tissues related to Jejunal Cancer:

38
Small Intestine, Liver, Skin, Colon

Publications for Jejunal Cancer

Articles related to Jejunal Cancer:

(show all 15)
# Title Authors Year
1
Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview. ( 25018888 )
2014
2
A case of Lynch syndrome with advanced jejunal cancer. ( 25373375 )
2014
3
Successful treatment of primary jejunal cancer after esophageal and colon cancer resection. ( 24620639 )
2013
4
Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations. ( 22886683 )
2012
5
Response to jejunal cancer in patients with familial adenomatous polyposis. ( 21182984 )
2011
6
Jejunal cancer in patients with familial adenomatous polyposis. ( 20621624 )
2010
7
Jejunal cancer in patients with familial adenomatous polyposis. ( 20399906 )
2010
8
Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case. ( 21046510 )
2010
9
Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. ( 19404084 )
2009
10
A case of primary jejunal cancer diagnosed by preoperative small intestinal endoscopy. ( 21318964 )
2008
11
Education and imaging. Gastrointestinal: metallic stent for an obstructing jejunal cancer. ( 17074030 )
2006
12
Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation. ( 15816449 )
2005
13
Primary jejunal cancer. ( 16246696 )
2005
14
Two sisters with coeliac disease and jejunal cancer: just a coincidence? ( 8446219 )
1993
15
Jejunal cancer; a case report. ( 20992565 )
1946

Variations for Jejunal Cancer

Expression for Jejunal Cancer

Search GEO for disease gene expression data for Jejunal Cancer.

Pathways for Jejunal Cancer

GO Terms for Jejunal Cancer

Biological processes related to Jejunal Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 base-excision repair GO:0006284 8.62 MUTYH WRN

Sources for Jejunal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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