MCID: JJN003
MIFTS: 29

Jejunal Cancer malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Jejunal Cancer

Aliases & Descriptions for Jejunal Cancer:

Name: Jejunal Cancer 12 14
Malignant Neoplasm of Jejunum 12 69
Jejunal Neoplasms 42 69
Jejunal Neoplasm 12 14
Malignant Tumor of Jejunum 12
Neoplasm of Jejunum 12
Tumor of Jejunum 12
Jejunal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13499 DOID:3218
ICD10 33 C17.1
ICD9CM 35 152.1
MeSH 42 D007580
NCIt 47 C8401

Summaries for Jejunal Cancer

MalaCards based summary : Jejunal Cancer, also known as malignant neoplasm of jejunum, is related to jejunal adenocarcinoma and htr2a-related altered drug metabolism. An important gene associated with Jejunal Cancer is GAN (Gigaxonin). The drugs Pancrelipase and Menthol have been mentioned in the context of this disorder. Affiliated tissues include colon and small intestine, and related phenotype is neoplasm.

Related Diseases for Jejunal Cancer

Diseases related to Jejunal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
id Related Disease Score Top Affiliating Genes
1 jejunal adenocarcinoma 10.9
2 htr2a-related altered drug metabolism 10.0 MUC6 MUTYH
3 pacinian tumor 9.9 KIT MUC6
4 neuroretinitis 9.8 KIT MUC6
5 t-cell large granular lymphocyte leukemia 9.8 MUTYH WRN
6 proctitis 9.8 KIT MUTYH
7 familial adenomatous polyposis 9.8
8 advanced sleep phase syndrome 9.8 KIT MUTYH
9 angiodysplasia 9.6
10 smooth muscle tumor 9.6
11 intestinal obstruction 9.6
12 gastrointestinal stromal tumor 9.6
13 esophagitis 9.5
14 lynch syndrome 9.5
15 desmoid tumor 9.5
16 squamous cell carcinoma 9.5
17 intestinal perforation 9.5
18 trigonitis 9.3 GAN KIT MUC6 MUTYH WRN

Comorbidity relations with Jejunal Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Intestinal Obstruction

Graphical network of the top 20 diseases related to Jejunal Cancer:



Diseases related to Jejunal Cancer

Symptoms & Phenotypes for Jejunal Cancer

MGI Mouse Phenotypes related to Jejunal Cancer:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 KIT MUTYH WRN

Drugs & Therapeutics for Jejunal Cancer

Drugs for Jejunal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pancrelipase Approved Phase 3,Phase 1 53608-75-6
2
Menthol Approved Phase 3 2216-51-5 16666
3
Octreotide Approved, Investigational Phase 3 83150-76-9 383414 6400441
4 pancreatin Phase 3,Phase 1
5 Gastrointestinal Agents Phase 3,Phase 1
6 Chelating Agents Phase 3
7 Antineoplastic Agents, Hormonal Phase 3
8 Cola Nutraceutical Phase 3
9 Pharmaceutical Solutions Phase 2
10
Simvastatin Approved Phase 1 79902-63-9 54454
11
Topotecan Approved, Investigational Phase 1 119413-54-6, 123948-87-8 60700
12
Cyclophosphamide Approved, Investigational Phase 1 50-18-0, 6055-19-2 2907
13
Lenograstim Approved Phase 1 135968-09-1
14 Alkylating Agents Phase 1
15 topoisomerase I inhibitors Phase 1
16 Mitogens Phase 1
17 Adjuvants, Immunologic Phase 1
18 Topoisomerase Inhibitors Phase 1
19 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 1
20 Hypolipidemic Agents Phase 1
21 Immunosuppressive Agents Phase 1
22 Anticholesteremic Agents Phase 1
23 Lipid Regulating Agents Phase 1
24 Antimetabolites Phase 1
25 Antirheumatic Agents Phase 1
26 Antineoplastic Agents, Alkylating Phase 1
27
Loperamide Approved 53179-11-6 3955
28 Fluorodeoxyglucose F18
29 Antidiarrheals
30 Immunoglobulins
31 Antibodies

Interventional clinical trials:

(show all 48)
id Name Status NCT ID Phase
1 Endoscopic Detection of Dysplasia in Crohn 's Disease Patient Completed NCT01180452 Phase 4
2 Roux-en-Y Versus Billroth II Reconstruction After Subtotal Gastrectomy in Gastric Cancer Comorbid With Type II Diabetes Unknown status NCT01528059 Phase 2, Phase 3
3 Evaluation of A New Digestive Reconstruction Procedure Following Pancreatoduodenectomy Unknown status NCT01931449 Phase 3
4 Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Health-Related Quality of Life in Patients Undergoing Total Gastrectomy for Adenocarcinoma Completed NCT01491698 Phase 3
5 Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy Completed NCT01731821 Phase 3
6 Functional Jejunal Interposition Improve Nutritional Status After Total Gastrectomy Recruiting NCT01996059 Phase 3
7 Comparison of Laparoscopic Proximal Gastrectomy and Laparoscopic Total Gastrectomy Recruiting NCT02892643 Phase 3
8 Roux-en-Y vs. Roux-en-Y+ Pouch for D2 Total Gastrectomy Recruiting NCT02110628 Phase 3
9 Cattell-Warren Versus Blumgart Techniques of Pancreatico-jejunostomy Following Pancreato-duodenectomy Recruiting NCT02457156 Phase 3
10 Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy Not yet recruiting NCT02288728 Phase 3
11 Uncut Roux-en-y Anastomosis Reduce Postoperative Complication and Improve Nutritional Status After Distal Gastrectomy Not yet recruiting NCT02763878 Phase 3
12 Comparison Study for Bile Reflux and Gastric Stasis in Patients After Distal Gastrectomy Withdrawn NCT00622804 Phase 3
13 External Drainage Versus Internal Drainage of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD) Unknown status NCT01634971 Phase 2
14 Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy Unknown status NCT01607307 Phase 2
15 Evaluating Weight Stability of Pancreatic Cancer Cachexia Patients Recruiting NCT02400398 Phase 2
16 Uncut Roux-en-Y Gastrojejunostomy for Early Gastric Cancer Patients Recruiting NCT02644148 Phase 2
17 The Safety and Feasibility of Laparoscopic Total Gastrectomy for Remnant Gastric Cancer Enrolling by invitation NCT02792881 Phase 2
18 ENDOBARRIER® and Conventional Therapy in the Management of Metabolic Syndrome in Obese Patients Suspended NCT02297555 Phase 1, Phase 2
19 Pancreaticogastrostomy Versus Pancreaticojejunostomy in Reconstruction After Cephalic Duodenopancreatectomy Unknown status NCT01324856 Phase 1
20 Evaluation of Four Reconstructions After Total Gastrectomy Unknown status NCT00677456 Phase 1
21 Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors Recruiting NCT02390843 Phase 1
22 Magnetic Anastomosis Device Relief of Malignant Gastric Outlet Obstruction Terminated NCT00487552 Phase 1
23 Digestive Tract Reconstruction After Gastrectomy of Gastric Cancer With Type 2 Diabetes Unknown status NCT01637350
24 Improving Diabetes by Reconstruction Methods in Gastric Cancer Patients With Diabetes Mellitus Unknown status NCT01375738
25 Anastomotic Techniques in Pancreaticoduodenectomy Unknown status NCT00855985
26 Evaluation of a Novel Pancreaticojejunostomy Technique for Pancreaticoduodenectomy Unknown status NCT01696903
27 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
28 Gastric Decompression After Sub-total Gastrectomy Completed NCT01073046
29 Novel Esophago-Jejunal Anastomosis Method During Totally Laparoscopic Total Gastrectomy Completed NCT02330913
30 Reconstruction Following Pancreaticoduodenectomy: A Randomized Clinical Trial of Pancreaticojejunostomy vs Pancreaticogastomy Completed NCT00841607
31 A Trial of the Jejunal Diversion Procedure Completed NCT02283632
32 Functional Voice and Speech Outcomes Following Surgical Voice Restorations: A Comparison of Pharyngeal Construction Approaches Completed NCT00600223
33 Safety and Efficacy of Long Limb Roux-en Y Reconstruction Completed NCT01373346
34 Current Management of Gastrointestinal Stromal Tumors (GIST) in the Region of Coquimbo Completed NCT00564265
35 Isolated Roux Loop Pancreaticojejunostomy Versus Pancreaticogastrostomy After Pancreaticoduodenectomy Completed NCT01859806
36 Randomized Controlled Trial on Pancreatic Stent Tube in Pancreaticoduodenectomy Completed NCT00628186
37 Individualized Nutrition for Adult Recipients of Allogeneic Stem Cell Transplants - Effect on Quality of Life Completed NCT01181076
38 Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following Pancreaticoduodenectomy Completed NCT01191138
39 Omentectomy and Metabolic Syndrome Completed NCT00923260
40 Comparisons Between Isoperistaltic and Antiperistaltic Gastrojejunostomy in Laparoscopic Distal Gastrectomy Recruiting NCT02837874
41 Enteral Nutrition After Pancreaticoduodenectomy Recruiting NCT03150615
42 Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticoduodenectomy Recruiting NCT02954302
43 Clinical Trial for Weight Regain Post-RYGB: APC Versus APC Plus Endoscopic Suture Technique Recruiting NCT03094936
44 Comparison of Feasibility Between Internal and External Pancreatic Drainage in Pancreaticoduodenectomy Active, not recruiting NCT01023594
45 Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative Complication in Patients Undergoing Pancreatoduodenectomy Not yet recruiting NCT03083938
46 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132
47 Enteral Feeding in Discharged Patients Terminated NCT02155140
48 Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy Terminated NCT02609100

Search NIH Clinical Center for Jejunal Cancer

Cochrane evidence based reviews: jejunal neoplasms

Genetic Tests for Jejunal Cancer

Anatomical Context for Jejunal Cancer

MalaCards organs/tissues related to Jejunal Cancer:

39
Colon, Small Intestine

Publications for Jejunal Cancer

Articles related to Jejunal Cancer:

(show all 15)
id Title Authors Year
1
A case of Lynch syndrome with advanced jejunal cancer. ( 25373375 )
2014
2
Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview. ( 25018888 )
2014
3
Successful treatment of primary jejunal cancer after esophageal and colon cancer resection. ( 24620639 )
2013
4
Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations. ( 22886683 )
2012
5
Response to jejunal cancer in patients with familial adenomatous polyposis. ( 21182984 )
2011
6
Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case. ( 21046510 )
2010
7
Jejunal cancer in patients with familial adenomatous polyposis. ( 20399906 )
2010
8
Jejunal cancer in patients with familial adenomatous polyposis. ( 20621624 )
2010
9
Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. ( 19404084 )
2009
10
A case of primary jejunal cancer diagnosed by preoperative small intestinal endoscopy. ( 21318964 )
2008
11
Education and imaging. Gastrointestinal: metallic stent for an obstructing jejunal cancer. ( 17074030 )
2006
12
Primary jejunal cancer. ( 16246696 )
2005
13
Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation. ( 15816449 )
2005
14
Two sisters with coeliac disease and jejunal cancer: just a coincidence? ( 8446219 )
1993
15
Jejunal cancer; a case report. ( 20992565 )
1946

Variations for Jejunal Cancer

Expression for Jejunal Cancer

Search GEO for disease gene expression data for Jejunal Cancer.

Pathways for Jejunal Cancer

GO Terms for Jejunal Cancer

Biological processes related to Jejunal Cancer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 base-excision repair GO:0006284 8.62 MUTYH WRN

Sources for Jejunal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....