Aliases & Classifications for Joint Disorders

Aliases & Descriptions for Joint Disorders:

Name: Joint Disorders 38 41
Arthropathy 69

Summaries for Joint Disorders

MedlinePlus : 41 a joint is where two or more bones come together, like the knee, hip, elbow, or shoulder. joints can be damaged by many types of injuries or diseases, including arthritis - inflammation of a joint. it causes pain, stiffness, and swelling. over time, the joint can become severely damaged. bursitis - inflammation of a fluid-filled sac that cushions the joint dislocations - injuries that force the ends of the bones out of position treatment of joint problems depends on the cause. if you have a sports injury, treatment often begins with the rice (rest, ice, compression, and elevation) method to relieve pain, reduce swelling, and speed healing. other possible treatments include pain relievers, keeping the injured area from moving, rehabilitation, and sometimes surgery. for arthritis, injuries, or other diseases, you may need joint replacement surgery to remove the damaged joint and put in a new one. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary : Joint Disorders, also known as arthropathy, is related to rheumatoid arthritis and osteochondritis dissecans, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Joint Disorders is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Etanercept and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and endothelial, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and hematopoietic system

Wikipedia : 71 An arthropathy is a disease of a... more...

Related Diseases for Joint Disorders

Diseases related to Joint Disorders via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
id Related Disease Score Top Affiliating Genes
1 rheumatoid arthritis 27.9 CSF1 IL11 IL17A IL1B IL1R1 IL1RN
2 osteochondritis dissecans 10.4
3 adenosine monophosphate deaminase 1 deficiency 10.4
4 crystal arthropathies 10.4
5 familial osteochondritis dissecans 10.4
6 exostosis 10.3
7 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 IL6 TNF
8 intussusception 10.3 IL1B TNF
9 arthropathy 10.3
10 alcoholic hepatitis 10.3 IL6 SERPINB2 TNF
11 angiomyoma 10.3 MMP3 PLAU TIMP1
12 orthostatic proteinuria 10.3 IL1RN IL6 TNF
13 carotenemia 10.3 IL6 MMP3 TNF
14 kidney leiomyosarcoma 10.3 IL1RN IL6 MMP3
15 intracranial arteriosclerosis 10.3 IL18R1 IL6 TNF
16 myiasis 10.2 IL1RN IL6 TNF
17 trichomalacia 10.2 IL17A IL6 TNF
18 germ cell and embryonal cancer 10.2 IL6 MMP3 TIMP1
19 gastric dilatation 10.2 IL17A IL6 TNF
20 anal paget's disease 10.2 IL1B IL6 TNF
21 bipolar i disorder 10.2 IL1B IL6 TNF
22 human immunodeficiency virus infectious disease 10.2 IL1B IL6 TNF
23 choanal atresia, bilateral 10.2 IL17A IL6 TNF
24 tinea capitis 10.2 IL1B IL6 TNF
25 measles 10.2 IL1B IL6 TNF
26 hypoparathyroidism-retardation-dysmorphism syndrome 10.2 IL1B IL6 TNF
27 crohn's colitis 10.2 IL17A IL6 TNF
28 mikulicz disease 10.2 IL1B IL6 TNF
29 acquired thrombocytopenia 10.2 IL1B IL6 TNF
30 dermatitis herpetiformis 10.2 IL17A MMP3 TNF
31 rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies 10.2 IL1B IL6 TNF
32 ectodermal dysplasia bartalos type 10.2 IL1B IL6 TNF
33 mineral metabolism disease 10.2 IL1B IL6 TNF
34 migraine with aura 10.2 IL1B IL6 TNF
35 disease of mental health 10.2 IL17A IL6 TNF
36 plague 10.2 PLAU TNF TNFSF11
37 bladder signet ring cell adenocarcinoma 10.2 IL1B IL6 TNF
38 dysbaric osteonecrosis 10.2 DKK1 IL6 TNFSF11
39 follicular adenoma 10.2 IL17A IL6 TNF
40 neuropathy 10.2 IL1B IL6 TNF
41 splenic artery aneurysm 10.2 IL1B IL6 TNF
42 cholera 10.2 IL1B IL6 TIMP1
43 inappropriate adh syndrome 10.2 IL1B IL6 TNF
44 central nervous system lymphoma 10.2 IL1B IL6 TNF
45 labyrinthitis 10.2 IL1B IL6 TNF
46 pancreas lymphoma 10.2 IL1B IL6 TNF
47 primary ciliary dyskinesia 10.2 IL1R1 IL6 TNF
48 atrophy of prostate 10.2 IL1B IL6 TNF
49 chondrodysplasia punctata, rhizomelic, type 1 10.2 IL1B MMP3 TIMP1
50 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 10.2 IL6 MMP3 TIMP1 TNF

Graphical network of the top 20 diseases related to Joint Disorders:



Diseases related to Joint Disorders

Symptoms & Phenotypes for Joint Disorders

UMLS symptoms related to Joint Disorders:


arthralgia, back pain, metatarsalgia, muscle cramp, sciatica, joint swelling, other symptoms referable to joint, other symptoms referable to joint, shoulder region, other symptoms referable to joint, upper arm, other symptoms referable to joint, forearm, other symptoms referable to joint, hand, other symptoms referable to joint, pelvic region and thigh, other symptoms referable to joint, lower leg, other symptoms referable to joint, ankle and foot, other symptoms referable to joint, other specified sites, other symptoms referable to joint, multiple sites, joint stiffness, musculoskeletal symptom, other symptoms referable to joint, site unspecified, joint symptom, stiffness of joint, not elsewhere classified in icd10cm

GenomeRNAi Phenotypes related to Joint Disorders according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.55 CSF1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-142 9.55 CSF1 TNFSF11
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.55 TNFSF11
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.55 IL1RN
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-175 9.55 TNFSF11
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.55 CSF1 IL18R1 IL1RN PLAU TNFSF11
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.55 PLAU
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.55 IL18R1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.55 PLAU
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.55 CSF1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.55 CSF1 TNFSF11

MGI Mouse Phenotypes related to Joint Disorders:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.28 CSF1 IL17A IL18R1 IL1B IL1R1 IL1RN
2 homeostasis/metabolism MP:0005376 10.25 CSF1 DKK1 IL17A IL1B IL1R1 IL1RN
3 growth/size/body region MP:0005378 10.23 DKK1 IL17A IL1R1 IL1RN IL6 IL6R
4 immune system MP:0005387 10.21 CSF1 IL17A IL18R1 IL1B IL1R1 IL1RN
5 endocrine/exocrine gland MP:0005379 10.13 CSF1 IL17A IL1R1 IL6 IL6R PLAU
6 mortality/aging MP:0010768 10.13 CSF1 DKK1 IL17A IL1B IL1R1 IL1RN
7 craniofacial MP:0005382 10.04 CSF1 DKK1 IL17A IL1R1 PLAU TNF
8 muscle MP:0005369 9.8 IL1R1 IL6 PLAU SERPINB2 TNF TNFSF11
9 neoplasm MP:0002006 9.76 IL1B IL1R1 IL6 IL6R PLAU TIMP1
10 respiratory system MP:0005388 9.61 CSF1 DKK1 IL17A IL1R1 IL6 PLAU
11 skeleton MP:0005390 9.4 CSF1 DKK1 IL17A IL1B IL1R1 IL1RN

Drugs & Therapeutics for Joint Disorders

Drugs for Joint Disorders (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 776)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 185243-69-0
2
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 9004-61-9 53477741 24759
3
Methyclothiazide Approved Phase 4 135-07-9 4121
4
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
5
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
6
Bevacizumab Approved, Investigational Phase 4 216974-75-3
7
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
8
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1 1197-18-8 5526
9
Milnacipran Approved Phase 4 92623-85-3 65833
10
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Phase 2 51-41-2 439260
11
Rivaroxaban Approved Phase 4,Phase 2,Phase 3 366789-02-8
12
Tranylcypromine Approved Phase 4 155-09-9 441233
13
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
14
Ropivacaine Approved Phase 4,Phase 2,Phase 3 84057-95-4 71273 175805
15
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2 169590-42-5 2662
16
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22204-53-1 1302 156391
17
Nabumetone Approved Phase 4 42924-53-8 4409
18
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
19
Denosumab Approved Phase 4,Phase 2,Phase 1 615258-40-7
20
Cimetidine Approved Phase 4,Phase 3,Phase 2 51481-61-9 2756
21
Hyoscyamine Approved Phase 4 101-31-5 64692
22
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2 118-42-3 3652
23
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3
24
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
25
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 83-43-2 6741
26
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 16590-41-3 5360515
27
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-24-8 5755
28
Sulfasalazine Approved Phase 4,Phase 3,Phase 2 599-79-1 5353980 5359476
29
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75706-12-6 3899
30
Anastrozole Approved, Investigational Phase 4 120511-73-1 2187
31
Letrozole Approved, Investigational Phase 4,Phase 2 112809-51-5 3902
32
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1 331731-18-1 16219006
33
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 15307-86-5 3033
34
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 202409-33-4 123619
35
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1 332348-12-6 10237
36
rituximab Approved Phase 4,Phase 2,Phase 3,Phase 1 174722-31-7 10201696
37
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 124-94-7 31307
38
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
39
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 137-58-6 3676
40
Menthol Approved Phase 4,Phase 3,Phase 2,Early Phase 1 2216-51-5 16666
41
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2180-92-9, 38396-39-3 2474
42
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
43
Meloxicam Approved, Vet_approved Phase 4,Phase 3,Phase 2 71125-38-7 5281106 54677470
44
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2 428863-50-7
45
Ibuprofen Approved Phase 4,Phase 3,Phase 1,Phase 2 15687-27-1 3672
46
Dopamine Approved Phase 4,Phase 3,Phase 1,Phase 2 51-61-6, 62-31-7 681
47
Ketorolac Approved Phase 4,Phase 3,Phase 2 74103-06-3, 66635-83-4 3826
48
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
49 Parecoxib Approved Phase 4,Phase 3 198470-84-7
50
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774

Interventional clinical trials:

(show top 50) (show all 5000)
id Name Status NCT ID Phase
1 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
2 Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis Unknown status NCT00144820 Phase 4
3 Artelon Metatarsophalangeal (MTP) Spacer Unknown status NCT01028469 Phase 4
4 A Randomised Single Centre Study to Compare the Long-Term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement Unknown status NCT00208442 Phase 4
5 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4
6 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
7 Investigation of Sacroiliac Fusion Treatment (INSITE) Unknown status NCT01681004 Phase 4
8 Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens Unknown status NCT02314325 Phase 4
9 Comparison Between Anterior and Direct Lateral Approach in Total Hip Arthroplasty Unknown status NCT01578746 Phase 4
10 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
11 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4
12 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
13 The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Unknown status NCT00422643 Phase 4
14 Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic Synovitis Unknown status NCT02060305 Phase 4
15 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4
16 Tranexamic Acid in Knee Joint Surgery Unknown status NCT02278263 Phase 4
17 A Randomized Controlled Trial of Long Versus Short Wait For Primary Total Hip and Knee Arthroplasty Unknown status NCT00138892 Phase 4
18 Hip Viscosupplementation: What is the Best Dosage? Unknown status NCT01810809 Phase 4
19 Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis Unknown status NCT01329406 Phase 4
20 Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy Unknown status NCT02000297 Phase 4
21 Reinflation After Early Tourniquet Release in Total Knee Arthroplasty Unknown status NCT01832272 Phase 4
22 Effectiveness Study of Hylan G-F 20 to Preserve Cartilage in Osteoarthritis of the Knee Unknown status NCT00393393 Phase 4
23 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4
24 Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE) Unknown status NCT02323451 Phase 4
25 The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics Unknown status NCT00778076 Phase 4
26 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4
27 Trial Comparing Navigated and Conventional Implantation Techniques in Knee Replacement Surgery Unknown status NCT00431509 Phase 4
28 Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty Unknown status NCT02152917 Phase 4
29 Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR) Unknown status NCT01973530 Phase 4
30 Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Unknown status NCT01233739 Phase 4
31 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4
32 Intraarticular Xylitol Injections for Knee Osteoarthritis Unknown status NCT02104596 Phase 4
33 To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients of the Knee Unknown status NCT02049606 Phase 4
34 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4
35 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4
36 Denosumab in Enhancement of Bone Bonding of Hip Prosthesis in Postmenopausal Women Unknown status NCT01926158 Phase 4
37 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
38 RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem Unknown status NCT01618084 Phase 4
39 Assessment of the Effects of Chondroitin Sulphate in Patients With Knee Osteoarthritis With Functional Magnetic Resonance Imaging (fMRI) Unknown status NCT01226615 Phase 4
40 Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty Unknown status NCT01027819 Phase 4
41 Use of Cold and Compression Therapy With Total Knee Replacement Patients Unknown status NCT00712816 Phase 4
42 Effect of Flex-a-New on Osteoarthritis of the Knee Unknown status NCT00294801 Phase 4
43 Comparing Clinical Outcome of 2 Different Total Knee Prostheses: Nexgen LPS-Flex Versus AGC Unknown status NCT00294528 Phase 4
44 Efficacy of Celecoxib Vs Placebo to Prevent Pain in a Paced Walk Unknown status NCT00194090 Phase 4
45 Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J) Unknown status NCT00974493 Phase 4
46 RFN for SIJ Disease Study Unknown status NCT01726608 Phase 4
47 The Long-term Evaluation of Glucosamine Sulphate Study Unknown status NCT00513422 Phase 4
48 Bipolar Sealer Aquamantys Use in Total Knee Replacement Unknown status NCT01736644 Phase 4
49 Rheumatoid Arthritis Patients in Training Unknown status NCT00434200 Phase 4
50 TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis Unknown status NCT00908089 Phase 4

Search NIH Clinical Center for Joint Disorders

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Joint Disorders cell therapies at LifeMap Discovery.

Genetic Tests for Joint Disorders

Anatomical Context for Joint Disorders

MalaCards organs/tissues related to Joint Disorders:

39
Bone, Skin, Endothelial, Brain

Publications for Joint Disorders

Articles related to Joint Disorders:

(show top 50) (show all 85)
id Title Authors Year
1
The effect of a functional appliance in the management of temporomandibular joint disorders in patients with juvenile idiopathic arthritis. ( 27716739 )
2017
2
EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update. ( 27697765 )
2017
3
An Analysis of Pathological Activities of CCN Proteins in Joint Disorders: Mechanical Stretch-Mediated CCN2 Expression in Cultured Meniscus Cells. ( 27734404 )
2017
4
Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. ( 28067817 )
2017
5
Dentists' knowledge of occlusal splint therapy for bruxism and temporomandibular joint disorders. ( 27251967 )
2016
6
Comparison of High-field and Low-field Magnetic Resonance Imaging of Stifle Joint Disorders in Dogs. ( 27760030 )
2016
7
Correlation between skeletal Class II and temporo-mandibular joint disorders: a literature review. ( 26938175 )
2016
8
An institutional survey for knowledge-based and self-awareness assessment in temporomandibular joint disorders among dental students. ( 27411654 )
2016
9
Evaluation of validity and reliability of a methodology for measuring human postural attitude and its relation to temporomandibular joint disorders. ( 26768173 )
2016
10
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). ( 26746234 )
2016
11
Blue rubber bleb nevus syndrome with knee joint disorder. ( 27117831 )
2016
12
Diagnosis of temporomandibular joint disorders: indication of imaging exams. ( 26832630 )
2016
13
Osteoblastoma of the temporal articular tubercle misdiagnosed asA a temporomandibular joint disorder. ( 28043747 )
2016
14
WITHDRAWN: Occlusal adjustment for treating and preventing temporomandibular joint disorders. ( 26727292 )
2016
15
Feature selection and classification methodology for the detection of knee-joint disorders. ( 27000292 )
2016
16
Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders. ( 27704395 )
2016
17
Synovial fluid matrix metalloproteinase-2 and -9 activities in dogs suffering from joint disorders. ( 26902805 )
2016
18
Temporomandibular Joint Disorders and Orofacial Pain. ( 26614951 )
2016
19
Improved Therapeutic Efficacy in Bone and Joint Disorders by Targeted Drug Delivery to Bone. ( 27803481 )
2016
20
Atherosclerotic cardiovascular disease in patients with chronic inflammatory joint disorders. ( 26888573 )
2016
21
Cerezen device provides treatment for temporomandibular joint disorders day and night. ( 27338922 )
2016
22
Association Between Harmful Oral Habits and Sign and Symptoms of Temporomandibular Joint Disorders Among Adolescents. ( 26436046 )
2015
23
The Evaluation of Head and Craniocervical Posture among Patients with and without Temporomandibular Joint Disorders- A Comparative Study. ( 26436048 )
2015
24
Temporomandibular joint disorders treated with articular injection: the effectiveness of plasma rich in growth factors-Endoret. ( 25974777 )
2015
25
Temporomandibular Joint Disorders in Patients With Different Facial Morphology. A Systematic Review of the Literature. ( 26255097 )
2015
26
Can pterygoid plate asymmetry be linked to temporomandibular joint disorders? ( 26125003 )
2015
27
Stakeholder engagement analysis - a bioethics dilemma in patient-targeted intervention: patients with temporomandibular joint disorders. ( 25600231 )
2015
28
Cell therapy in joint disorders. ( 25553210 )
2015
29
Quantitative measurements of the articular areas of mandibular condyles with temporomandibular joint disorders using magnetic resonance imaging. ( 26715262 )
2015
30
Modeling of muscle forces in humans with and without temporomandibular joint disorders. ( 25865546 )
2015
31
Contemporary management of temporomandibular joint disorders. ( 25483451 )
2015
32
Joint Arthroplasty With Osteochondral Grafting From the Knee for Posttraumatic or Degenerative Hand Joint Disorders. ( 26143968 )
2015
33
Temporomandibular joint disorder from skull-base osteomyelitis: a case report. ( 26550559 )
2015
34
Comparison of Serum and Salivary Antioxidants in Patients with Temporomandibular Joint Disorders and Healthy Subjects. ( 26622281 )
2015
35
Imaging Approach to Temporomandibular Joint Disorders. ( 26374243 )
2015
36
A pilot study of ambulatory masticatory muscle activities in temporomandibular joint disorders diagnostic groups. ( 25865543 )
2015
37
Botulinum toxin therapy for temporomandibular joint disorders: a systematic review of randomized controlled trials. ( 25920597 )
2015
38
Cytokine profile in the synovial fluid of patients with temporomandibular joint disorders: A systematic review. ( 26556103 )
2015
39
Dickkopfa89related protein 1 induces angiogenesis by upregulating vascular endothelial growth factor in the synovial fibroblasts of patients with temporomandibular joint disorders. ( 26239269 )
2015
40
Bone and Joint Disorders in Acromegaly. ( 25633971 )
2015
41
WITHDRAWN: Arthrocentesis and lavage for treating temporomandibular joint disorders. ( 26677172 )
2015
42
Synovial plicae and temporomandibular joint disorders: surgical findings. ( 25795190 )
2015
43
Association between Ear Fullness, Earache, and Temporomandibular Joint Disorders in the Elderly. ( 25992127 )
2014
44
Brain signature of chronic orofacial pain: a systematic review and meta-analysis on neuroimaging research of trigeminal neuropathic pain and temporomandibular joint disorders. ( 24759798 )
2014
45
Pisotriquetral joint disorders: an under-recognized cause of ulnar side wrist pain. ( 24687844 )
2014
46
Quantitative measurements of the articular areas of mandibular condyles with temporomandibular joint disorders using magnetic resonance imaging. ( 25519808 )
2014
47
Joint motion quality in vibroacoustic signal analysis for patients with patellofemoral joint disorders. ( 25496721 )
2014
48
Comparing proton density and turbo spin echo T2 weighted static sequences with dynamic half-Fourier single-shot TSE pulse sequence at 3.0a88T in diagnosis of temporomandibular joint disorders: a prospective study. ( 24720606 )
2014
49
Signal intensity on fluid-attenuated inversion recovery images of condylar marrow changes correspond with slight pain in patients with temporomandibular joint disorders. ( 25177105 )
2014
50
Comprehensive treatment of temporomandibular joint disorders. ( 24660643 )
2014

Variations for Joint Disorders

Expression for Joint Disorders

Search GEO for disease gene expression data for Joint Disorders.

Pathways for Joint Disorders

Pathways related to Joint Disorders according to GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.99 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
2
Show member pathways
13.88 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
3
Show member pathways
13.65 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
4
Show member pathways
13.57 IL11 IL17A IL18R1 IL1B IL1R1 IL6
5
Show member pathways
13.33 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
6
Show member pathways
13.28 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
7
Show member pathways
13.21 CSF1 IL11 IL17A IL18R1 IL1B IL1R1
8
Show member pathways
13.04 IL18R1 IL1B IL1R1 IL1R2 IL1RN IL6
9
Show member pathways
12.76 IL1B IL1R1 IL1R2 IL6 TIMP1 TNF
10
Show member pathways
12.65 IL17A IL18R1 IL1B IL6 TIMP1 TNF
11
Show member pathways
12.63 IL17A IL18R1 IL1B IL1R1 IL6 IL6R
12 12.59 IL17A IL1B IL1RN TNF TNFSF11
13
Show member pathways
12.44 IL17A IL1B IL6 TNF
14 12.44 IL1R1 IL1R2 IL6 TNF
15
Show member pathways
12.39 IL17A IL1B IL6 IL6R MMP3 TNF
16
Show member pathways
12.36 CSF1 IL1B IL6 TNF
17
Show member pathways
12.33 IL1B IL1R1 IL1R2 IL1RN
18
Show member pathways
12.31 IL1B IL1R1 IL6 TNF
19 12.27 IL1R2 IL6 MMP3 PLAU
20
Show member pathways
12.24 IL11 IL1B IL1R1 IL6 TNF
21 12.23 IL1B IL1RN IL6 IL6R TNF
22
Show member pathways
12.2 IL17A IL1B IL6 TNF
23 12.14 IL1B IL1R1 IL1R2 TNF
24 12.12 CSF1 IL1B IL1R1 TNF TNFSF11
25 12.06 IL1B IL1R1 IL6 TNF
26 12.04 CSF1 IL11 IL6 TNF
27
Show member pathways
12.03 IL17A IL18R1 IL1B IL6 TNF
28 12.02 IL1B IL6 IL6R PLAU SERPINB2
29 12.01 CSF1 IL18R1 IL1B IL6 MMP3 TNF
30
Show member pathways
12 IL17A IL1B IL1R1 IL6 IL6R
31 11.97 IL17A IL1B IL6 IL6R MMP3 TIMP1
32 11.95 IL1B IL1R1 IL1R2 IL6 TNF
33 11.93 IL1B IL1R1 PLAU TNF TNFSF11
34 11.91 IL1B IL6 TNF
35 11.91 IL6 IL6R TIMP1
36
Show member pathways
11.91 MMP3 TIMP1 TNF
37
Show member pathways
11.9 IL6 IL6R TIMP1 TNFSF11
38
Show member pathways
11.88 IL17A IL6 IL6R
39 11.86 IL17A IL1B IL1R1 TNF
40 11.83 CSF1 IL1B IL6 TNF
41 11.78 IL1B IL6 TNF
42
Show member pathways
11.74 IL1B IL6 MMP3 TNF
43 11.74 CSF1 IL11 IL1B IL1R1 IL1R2 IL6
44 11.71 IL1B IL6 PLAU TIMP1 TNF
45 11.68 MMP3 PLAU TIMP1
46
Show member pathways
11.66 IL11 IL6 IL6R
47 11.63 IL1B IL6 TNF
48 11.58 IL1B IL6 TNF
49 11.57 IL1B IL6 TNF TNFSF11
50 11.56 IL6 PLAU TNF

GO Terms for Joint Disorders

Cellular components related to Joint Disorders according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 CSF1 DKK1 IL11 IL17A IL1B IL1RN
2 extracellular region GO:0005576 9.53 CSF1 DKK1 IL11 IL17A IL1B IL1R1
3 interleukin-6 receptor complex GO:0005896 9.16 IL6 IL6R
4 plasma membrane GO:0005886 10.03 CSF1 DKK1 IL18R1 IL1R1 IL1R2 IL1RAPL2

Biological processes related to Joint Disorders according to GeneCards Suite gene sharing:

(show all 38)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.97 CSF1 DKK1 IL1B IL6 TNF
2 inflammatory response GO:0006954 9.88 CSF1 IL17A IL1B IL1RN IL6 TNF
3 wound healing GO:0042060 9.85 IL6 SERPINB2 TIMP1
4 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.85 IL11 IL6 IL6R
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.84 IL1B IL6 TNF TNFSF11
6 positive regulation of protein kinase B signaling GO:0051897 9.83 IL6 TNF TNFSF11
7 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.82 IL11 IL6 TNF
8 response to glucocorticoid GO:0051384 9.81 IL1RN IL6 TNF
9 positive regulation of JNK cascade GO:0046330 9.8 IL1B TNF TNFSF11
10 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.8 IL1B IL6 TNF TNFSF11
11 response to cytokine GO:0034097 9.79 IL6 IL6R TIMP1
12 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 IL6 IL6R TNF
13 positive regulation of interferon-gamma production GO:0032729 9.76 IL18R1 IL1B TNF
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.74 IL1B IL6 TNF
15 monocyte chemotaxis GO:0002548 9.72 IL6 IL6R TNFSF11
16 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.68 IL1B TNF
17 positive regulation of leukocyte chemotaxis GO:0002690 9.67 IL6 IL6R
18 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.66 IL1B TNF
19 negative regulation of hormone secretion GO:0046888 9.65 IL11 IL6
20 positive regulation of chemokine biosynthetic process GO:0045080 9.65 IL1B TNF
21 negative regulation of lipid storage GO:0010888 9.63 IL6 TNF
22 interleukin-6-mediated signaling pathway GO:0070102 9.63 IL6 IL6R
23 osteoclast differentiation GO:0030316 9.63 CSF1 TNF TNFSF11