JNA
MCID: JVN033
MIFTS: 51

Juvenile Nasopharyngeal Angiofibroma (JNA) malady

Cancer diseases, Rare diseases categories

Summaries for Juvenile Nasopharyngeal Angiofibroma

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MalaCards based summary: Juvenile Nasopharyngeal Angiofibroma, also known as JNA, is related to familial adenomatous polyposis and nasopharyngitis. An important gene associated with Juvenile Nasopharyngeal Angiofibroma is BMI1 (BMI1 polycomb ring finger oncogene), and among its related pathways are Angiogenesis and Tyrosine Kinases / Adaptors. The compounds everolimus and triphenylethylene have been mentioned in the context of this disorder. Affiliated tissues include endothelial and retina, and related mouse phenotypes are liver/biliary system and craniofacial.

Aliases & Classifications for Juvenile Nasopharyngeal Angiofibroma

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Sources:
48Orphanet, 27ICD10 via Orphanet
See all sources

Juvenile Nasopharyngeal Angiofibroma, Aliases & Descriptions:

Name: Juvenile Nasopharyngeal Angiofibroma 48
 
Jna 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Orphanet: 48 
Rare tumors


External Ids:

ICD10 via Orphanet27 D10.6

Related Diseases for Juvenile Nasopharyngeal Angiofibroma

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Diseases related to Juvenile Nasopharyngeal Angiofibroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 137)
idRelated DiseaseScoreTop Affiliating Genes
1familial adenomatous polyposis30.6MYC, CDH1, CTNNB1
2nasopharyngitis11.5
3endotheliitis10.6
4angiodysplasia10.5ENG
5carney triad10.5KIT
6cerebral meningioma10.5PGR
7retinitis10.5
8hypoglycemic coma10.4IGF2
9spindle cell carcinoma10.4PGR, ACTC1
10dermatofibrosarcoma protuberans10.4ACTC1, KIT
11telangiectasia, hereditary hemorrhagic, type 510.4BMP6, ENG
12leiomyomatosis10.4PGR, ESR1
13gestational trophoblastic tumor10.4H19, PCNA
14prolymphocytic leukemia10.4MYC, ZAP70
15teratoma10.3ACTC1, H19, KIT
16telangiectasis10.3BMP6, ENG
17myelofibrosis10.3BMP6, FGF2
18progesterone resistance10.3ESR1, PGR
19embryonal cancer10.3IGF2, H19
20mammary paget's disease10.3PGR, ESR1
21diabetic macular edema10.3VEGFA
22uterine sarcoma10.3ESR1, KIT
23mesoblastic nephroma10.3IGF2, KIT
24bilateral breast cancer10.3PGR, ESR1
25alopecia10.3
26foster-kennedy syndrome10.3
27central retinal artery occlusion10.3
28fibrous histiocytoma10.3
29esotropia10.3
30fibrosarcoma10.3
31histiocytoma10.3
32retinal artery occlusion10.3
33follicular lymphoma10.3MYC, BMI1, ZAP70
34breast fibroadenoma10.3PGR, ESR1
35chronic myocardial ischemia10.3VEGFA, FGF2
36papilloma10.3ENG, PCNA, ACTC1
37li-fraumeni syndrome10.3PGR, ESR1
38gastrointestinal stromal tumor10.3KIT, PCNA, ACTC1
39middle ear cholesteatoma10.3PCNA, FGF2
40clear cell sarcoma10.3IGF2, KIT
41myoma10.3PGR, ESR1
42adenosarcoma10.3PGR, ESR1, ACTC1
43hemihypertrophy10.3IGF2, H19
44rhabdoid tumor10.3ACTC1, IGF2
45hypertrophic scars10.3TGFB3, BMP6, FGF2
46keloids10.3TGFB3, BMP6, FGF2
47hemangiopericytoma10.3IGF2, ACTC1
48uterine fibroid10.3ESR1, PGR
49corneal neovascularization10.3VEGFA, FGF2
50embryonal rhabdomyosarcoma10.3H19, ACTC1, IGF2

Graphical network of the top 20 diseases related to Juvenile Nasopharyngeal Angiofibroma:



Diseases related to juvenile nasopharyngeal angiofibroma

Symptoms for Juvenile Nasopharyngeal Angiofibroma

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Drugs & Therapeutics for Juvenile Nasopharyngeal Angiofibroma

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Drug clinical trials:

Search ClinicalTrials for Juvenile Nasopharyngeal Angiofibroma

Search NIH Clinical Center for Juvenile Nasopharyngeal Angiofibroma

Genetic Tests for Juvenile Nasopharyngeal Angiofibroma

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Anatomical Context for Juvenile Nasopharyngeal Angiofibroma

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MalaCards organs/tissues related to Juvenile Nasopharyngeal Angiofibroma:

32
Endothelial, Retina

Animal Models for Juvenile Nasopharyngeal Angiofibroma or affiliated genes

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MGI Mouse Phenotypes related to Juvenile Nasopharyngeal Angiofibroma:

36 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.9CTNNB1, KIT, MYC, ESR1, VEGFA, IGF2
2MP:00053827.6IGF2, VEGFA, TGFB3, MYC, BMI1, KIT
3MP:00053917.6IGF2, VEGFA, TGFB3, BMI1, KIT, CTNNB1
4MP:00053887.5IGF2, VEGFA, TGFB3, ESR1, BMI1, KIT
5MP:00053717.5IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
6MP:00020067.3VEGFA, PGR, ESR1, MYC, BMI1, H19
7MP:00053697.1IGF2, VEGFA, PGR, ESR1, MYC, ACTC1
8MP:00053817.1ESR1, TGFB3, VEGFA, IGF2, MYC, BMI1
9MP:00028737.1VEGFA, TGFB3, PGR, MYC, ACTC1, BMI1
10MP:00107716.9ESR1, PGR, VEGFA, IGF2, MYC, KIT
11MP:00053866.8IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
12MP:00036316.7ESR1, TGFB3, VEGFA, IGF2, MYC, BMI1
13MP:00053806.6IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
14MP:00030126.4ESR1, PGR, VEGFA, IGF2, MYC, H19
15MP:00053796.4ESR1, PGR, VEGFA, IGF2, MYC, BMI1
16MP:00053766.3ESR1, PGR, TGFB3, VEGFA, IGF2, MYC
17MP:00053856.3ESR1, PGR, TGFB3, VEGFA, IGF2, MYC
18MP:00053906.2FGF2, IGF2, VEGFA, TGFB3, PGR, ESR1
19MP:00053846.0MYC, ESR1, PGR, TGFB3, VEGFA, IGF2
20MP:00053976.0MYC, ESR1, PGR, VEGFA, IGF2, BMI1
21MP:00053876.0IGF2, VEGFA, PGR, ESR1, MYC, BMI1
22MP:00053895.8IGF2, VEGFA, PGR, ESR1, MYC, BMP6
23MP:00053785.5ACTC1, MYC, ESR1, VEGFA, IGF2, BMI1
24MP:00107685.2MYC, ESR1, PGR, TGFB3, VEGFA, IGF2

Publications for Juvenile Nasopharyngeal Angiofibroma

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Articles related to Juvenile Nasopharyngeal Angiofibroma:

(show top 50)    (show all 260)
idTitleAuthorsYear
1
Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. (23878770)
2013
2
Tenascin-C, GLUT-1, and syndecan-2 expression in juvenile nasopharyngeal angiofibroma: correlations to vessel density and tumor stage. (22791513)
2013
3
Endonasal endoscopic management of juvenile nasopharyngeal angiofibroma without angiographic embolization. (23271032)
2013
4
Bilateral non-superselective embolization with particles under transient occlusion of the internal carotid artery in the management of juvenile nasopharyngeal angiofibroma: technical note. (22903329)
2012
5
Juvenile nasopharyngeal angiofibroma with intradural extension. (22030982)
2011
6
Role of Le Fort type I osteotomy approach in juvenile nasopharyngeal angiofibroma. (21880465)
2011
7
Endoscopically assisted intratumoral embolization of juvenile nasopharyngeal angiofibroma using Onyx. (21631195)
2011
8
The changing surgical management of juvenile nasopharyngeal angiofibroma. (20848119)
2011
9
Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma. (21492601)
2010
10
Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study. (22319699)
2010
11
Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). (19922097)
2009
12
Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. (19842877)
2009
13
Juvenile nasopharyngeal angiofibroma in a tertiary centre: ten-year experience. (19352568)
2009
14
Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence and proposal of a staging system. (18623035)
2008
15
Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. (19668408)
2008
16
Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. (19144296)
2008
17
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA). (18227724)
2008
18
Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. (17556070)
2007
19
Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. (17285972)
2006
20
Orbital involvement in juvenile nasopharyngeal angiofibroma: prevalence and treatment. (15266144)
2004
21
Tissue maturation during the growth of juvenile nasopharyngeal angiofibroma. (14763569)
2004
22
Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. (11374252)
2001
23
Immunolocalization of activated transforming growth factor beta1 in juvenile nasopharyngeal angiofibroma. (10864108)
2000
24
Juvenile nasopharyngeal angiofibroma. (10410346)
1999
25
Noradrenergic innervation of juvenile nasopharyngeal angiofibroma. (8024761)
1994
26
Radiation therapy as an alternative to surgery in the management of intracranial juvenile nasopharyngeal angiofibroma. (8300314)
1993
27
Surgical experience with juvenile nasopharyngeal angiofibroma. (1337963)
1992
28
Juvenile nasopharyngeal angiofibroma: a trap for the unwary. (1322461)
1992
29
Juvenile nasopharyngeal angiofibroma in a static population: the implications of misdiagnosis. (2178075)
1990
30
Preoperative embolisation in the management of juvenile nasopharyngeal angiofibroma. (2561258)
1989
31
The treatment of advanced juvenile nasopharyngeal angiofibroma. (2553648)
1989
32
Juvenile nasopharyngeal angiofibroma. (3025797)
1986
33
Juvenile nasopharyngeal angiofibroma treated by radiotherapy. (3005454)
1986
34
Juvenile nasopharyngeal angiofibroma: an unusual presentation in the oral cavity. (2989749)
1985
35
Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. (6327493)
1984
36
A few points in the management of juvenile nasopharyngeal angiofibroma. (6325570)
1984
37
Oronasal fistula--a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. (6308111)
1983
38
Juvenile nasopharyngeal angiofibroma--the preferred treatment. (6301001)
1983
39
Clinicopathologic conferences. Case 46, Part II: Juvenile nasopharyngeal angiofibroma. (6306189)
1983
40
Juvenile nasopharyngeal angiofibroma. (6256588)
1980
41
Juvenile nasopharyngeal angiofibroma. (6255615)
1980
42
Juvenile nasopharyngeal angiofibroma. A report of seven cases. (205902)
1978
43
Angiographic evaluation of the regression of an extensive juvenile nasopharyngeal angiofibroma after radiation therapy: a case report with therapeutic implications. (4373112)
1974
44
Juvenile nasopharyngeal angiofibroma. (4344430)
1972
45
Juvenile nasopharyngeal angiofibroma. (4338568)
1972
46
Further experience in treatment of juvenile nasopharyngeal angiofibroma. (4305190)
1969
47
Juvenile nasopharyngeal angiofibroma. a theory of pathogenesis. (14442741)
1959
48
Sarcomatous transformation of a juvenile, nasopharyngeal angiofibroma. (13532703)
1958
49
Juvenile nasopharyngeal angiofibroma. (13087657)
1953
50
Juvenile Nasopharyngeal Angiofibroma. (17859097)
1948

Variations for Juvenile Nasopharyngeal Angiofibroma

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Expression for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Expression patterns in normal tissues for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

Search GEO for disease gene expression data for Juvenile Nasopharyngeal Angiofibroma.

Pathways for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Pathways related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7ENG, FGF2, TGFB3
29.6KIT, FGF2, ZAP70
39.5FGF2, TGFB3, VEGFA
4
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy37
9.5ACTC1, CTNNB1, TGFB3
5
Show member pathways
9.5VEGFA, TGFB3, MYC
6
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling59
Leptin signaling pathway37
9.5ESR1, MYC, ZAP70
7
Show member pathways
Cell cycle ESR1 regulation of G1 S transition59
Immune response MIF JAB1 signaling59
Cell cycle Cell cycle generic schema 59
9.5PGR, ESR1, MYC
8
Show member pathways
9.4BMP6, MYC, TGFB3
99.3ESR1, MYC, TGFB3, ENG
10
Show member pathways
Neurophysiological process Receptor mediated axon growth repulsion59
Pathogenic Escherichia coli infection37
9.3ACTC1, CTNNB1, CDH1
119.3ACTC1, CDH1, CTNNB1
129.2ESR1, CTNNB1, MYC
13
Show member pathways
9.2IGF2, TGFB3, VEGFA
14
Show member pathways
9.2FGF2, KIT, ESR1, PGR
15
Show member pathways
Development ERBB family signaling59
Development GDNF family signaling59
9.2CDH1, CTNNB1, MYC
169.2CTNNB1, CDH1, MYC
179.2CDH1, CTNNB1, MYC
189.1VEGFA, MYC, KIT, FGF2
199.0FGF2, KIT, IGF2, ACTC1
209.0BMP6, VEGFA, CTNNB1
219.0CTNNB1, MYC, IGF2
228.9CDH1, TGFB3, MYC, CTNNB1
238.8FGF2, CTNNB1, MYC, CDH1
248.8CTNNB1, MYC, TGFB3, ENG, ESR1
25
Show member pathways
Immune response IL 4 signaling pathway59
Signal transduction AKT signaling59
8.7MYC, IGF2, PCNA
26
Show member pathways
8.7VEGFA, TGFB3, BMP6, KIT, MYC
27
Show member pathways
Cell cycle37
8.6MYC, TGFB3, PCNA, CDH1
288.6IGF2, VEGFA, BMP6, FGF2
298.6TGFB3, PCNA, MYC, CTNNB1
30
Show member pathways
8.5IGF2, BMP6, TGFB3, ZAP70, FGF2
31
Show member pathways
8.5KIT, FGF2, TGFB3, BMP6, IGF2
32
Show member pathways
Signaling Pathways in Glioblastoma37
8.4CTNNB1, FGF2, VEGFA, CDH1, MYC
338.4TGFB3, MYC, BMP6, CTNNB1, CDH1
348.4CTNNB1, CDH1, MYC, VEGFA, ESR1
35
Show member pathways
8.2KIT, IGF2, BMP6, FGF2, ZAP70, TGFB3
36
Show member pathways
8.2ZAP70, FGF2, KIT, TGFB3, IGF2, BMP6
37
Show member pathways
8.2FGF2, ZAP70, KIT, BMP6, TGFB3, IGF2
38
Show member pathways
8.2KIT, VEGFA, ZAP70, CDH1, CTNNB1, FGF2
39
Show member pathways
8.0TGFB3, BMP6, KIT, CTNNB1, FGF2, IGF2
407.9VEGFA, TGFB3, MYC, KIT, CDH1, CTNNB1
41
Show member pathways
7.9IGF2, FGF2, ZAP70, KIT, BMP6, TGFB3
427.9FGF2, CTNNB1, MYC, ESR1, VEGFA, IGF2
43
Show member pathways
Signal transduction PTEN pathway59
7.8CTNNB1, KIT, PCNA, MYC, TGFB3, CDH1
44
Show member pathways
7.7IGF2, FGF2, KIT, TGFB3, MYC, CDH1
457.7VEGFA, CTNNB1, FGF2, PCNA, MYC, ESR1
46
Show member pathways
7.5TGFB3, FGF2, CTNNB1, CDH1, IGF2, BMP6
47
Show member pathways
7.5TGFB3, FGF2, ZAP70, KIT, BMP6, MYC
48
Show member pathways
7.3CTNNB1, MYC, ESR1, FGF2, KIT, PGR
49
Show member pathways
7.1CTNNB1, CDH1, KIT, BMP6, IGF2, FGF2
50
Show member pathways
6.5ESR1, MYC, TGFB3, IGF2, BMP6, KIT

Compounds for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Compounds related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 198)
idCompoundScoreTop Affiliating Genes
1everolimus44 50 1211.3VEGFA, KIT, MYC, ESR1
2triphenylethylene449.2PGR, ESR1, BMP6
3trastuzumab44 50 1210.9VEGFA, PGR, ESR1, KIT, CTNNB1
4danazol44 25 1210.7PGR, PCNA, CDH1, ESR1
5docetaxel44 50 60 1211.6PGR, ESR1, CDH1, VEGFA, KIT, MYC
6methylcellulose448.6CDH1, KIT, IGF2, CTNNB1, FGF2
7geldanamycin44 50 60 1211.5CTNNB1, CDH1, ESR1, PGR, KIT, VEGFA
8hyaluronic acid44 259.5VEGFA, BMP6, FGF2, MYC, ENG, CDH1
9progestin448.5IGF2, VEGFA, TGFB3, CDH1, ESR1, PGR
10dfmo44 29 6010.2MYC, CDH1, CTNNB1, IGF2
11celecoxib44 60 29 50 25 1213.2VEGFA, PCNA, CDH1, CTNNB1, FGF2
12matrigel448.1VEGFA, FGF2, ACTC1, CTNNB1, CDH1, ENG
13retinoid448.1CDH1, MYC, ESR1, BMP6, CTNNB1, PGR
14ribonucleic acid448.1ACTC1, IGF2, BMP6, H19, KIT, MYC
15pd 98,059448.1CDH1, CTNNB1, BMP6, MYC, KIT, ZAP70
164-hydroxytamoxifen448.0TGFB3, IGF2, ESR1, MYC, BMP6, CTNNB1
17tgf beta1448.0FGF2, CTNNB1, CDH1, BMP6, TGFB3, IGF2
18steroid448.0ACTC1, KIT, H19, IGF2, TGFB3, PGR
19methotrexate50 44 129.9CDH1, PGR, ESR1, PCNA, KIT, BMP6
20gefitinib44 50 129.9ESR1, KIT, CDH1, CTNNB1, IGF2, FGF2
21mg 13244 608.9CDH1, VEGFA, ESR1, MYC, PCNA, CTNNB1
22suramin44 29 129.8VEGFA, BMP6, FGF2, IGF2, PCNA
23imatinib44 50 129.7IGF2, VEGFA, CTNNB1, ZAP70, KIT, BMP6
24rapamycin447.6BMP6, CDH1, MYC, CTNNB1, IGF2, VEGFA
25dihydrotestosterone44 29 25 1210.5BMP6, PGR, ESR1, CDH1, CTNNB1, FGF2
26doxorubicin44 50 129.4ENG, CDH1, PGR, VEGFA, KIT, ESR1
27indomethacin44 29 60 1210.4PCNA, IGF2, CDH1, MYC, BMP6, PGR
28phosphatidylinositol447.3FGF2, IGF2, MYC, BMP6, KIT, ZAP70
29agar447.3FGF2, CTNNB1, CDH1, ENG, H19, BMP6
30ly294002447.3IGF2, FGF2, MYC, CTNNB1, CDH1, BMP6
31glutamine447.2CTNNB1, KIT, BMP6, PGR, IGF2, CDH1
32cycloheximide447.2BMP6, IGF2, VEGFA, PGR, ESR1, MYC
33heparin44 29 25 1210.1ZAP70, IGF2, BMP6, FGF2, PCNA, VEGFA
34genistein44 29 60 3 25 1212.1FGF2, CTNNB1, CDH1, ZAP70, PCNA, VEGFA
35testosterone44 60 25 1210.0PCNA, ACTC1, KIT, CTNNB1, PGR, ESR1
36oligonucleotide447.0MYC, KIT, BMP6, PCNA, ZAP70, ENG
375fluorouracil446.9IGF2, VEGFA, TGFB3, PGR, ESR1, PCNA
38cisplatin44 50 60 129.8VEGFA, ESR1, MYC, BMP6, CDH1, CTNNB1
395-aza-2deoxycytidine446.7PGR, ESR1, MYC, BMP6, H19, PCNA
40thymidine44 257.7IGF2, TGFB3, MYC, BMP6, H19, PCNA
41alanine446.7FGF2, CTNNB1, CDH1, BMP6, MYC, PCNA
42tamoxifen44 50 29 129.5ESR1, MYC, VEGFA, IGF2, BMP6, PGR
43progesterone44 29 60 25 1210.3IGF2, CTNNB1, CDH1, ENG, KIT, PCNA
44tyrosine446.2CDH1, ENG, IGF2, VEGFA, TGFB3, FGF2
45paclitaxel44 50 127.9VEGFA, PGR, ESR1, MYC, BMP6, PCNA
46dexamethasone44 50 29 128.6FGF2, CTNNB1, CDH1, ENG, ZAP70, PCNA
47retinoic acid44 256.6CDH1, H19, BMP6, ACTC1, MYC, KIT
48paraffin445.5PGR, TGFB3, VEGFA, IGF2, ESR1, MYC
49vegf445.2PCNA, BMP6, ACTC1, MYC, ESR1, PGR
50estrogen445.0ENG, FGF2, IGF2, KIT, PCNA, BMP6

GO Terms for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Cellular components related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:0163429.4CDH1, CTNNB1
2cytoplasmic side of plasma membraneGO:0098989.3KIT, CDH1, CTNNB1
3platelet alpha granule lumenGO:0310939.3VEGFA, TGFB3, IGF2
4cell surfaceGO:0099869.1TGFB3, ENG, CDH1, VEGFA
5nucleoplasmGO:0056547.9MYC, CTNNB1, PCNA, PGR, BMI1, ESR1
6extracellular spaceGO:0056157.8FGF2, IGF2, VEGFA, TGFB3, ACTC1, BMP6
7cytoplasmGO:0057376.5CTNNB1, VEGFA, CDH1, ENG, PCNA, BMP6

Biological processes related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 42)
idNameGO IDScoreTop Affiliating Genes
1detection of hypoxiaGO:07048310.4TGFB3, ENG
2central nervous system vasculogenesisGO:02200910.1CTNNB1, ENG
3positive regulation of collagen biosynthetic processGO:03296710.1TGFB3, ENG
4cell migration involved in sprouting angiogenesisGO:00204210.0FGF2, VEGFA
5positive regulation of blood vessel endothelial cell migrationGO:04353610.0VEGFA, FGF2
6mammary gland alveolus developmentGO:06074910.0ESR1, VEGFA
7artery morphogenesisGO:04884410.0VEGFA, ENG
8activation of MAPK activityGO:00018710.0FGF2, KIT, TGFB3
9transforming growth factor beta receptor signaling pathwayGO:00717910.0ENG, MYC, TGFB3
10positive regulation of fibroblast proliferationGO:0481469.9BMI1, ESR1, MYC
11positive regulation of phospholipase C activityGO:0108639.9KIT, FGF2, ESR1
12positive regulation of pathway-restricted SMAD protein phosphorylationGO:0108629.9ENG, BMP6, TGFB3
13positive regulation of phosphatidylinositol 3-kinase activityGO:0435529.9KIT, FGF2
14cellular response to indole-3-methanolGO:0716819.9CTNNB1, CDH1
15regulation of protein localization to cell surfaceGO:20000089.9CTNNB1, CDH1
16digestive tract developmentGO:0485659.9TGFB3, KIT
17positive regulation of gene expressionGO:0106289.8ENG, VEGFA, KIT
18response to hypoxiaGO:0016669.8TGFB3, ENG, VEGFA
19positive regulation of neuroblast proliferationGO:0020529.8VEGFA, CTNNB1
20positive regulation of endothelial cell differentiationGO:0456039.8CTNNB1, BMP6
21patterning of blood vesselsGO:0015699.7VEGFA, ENG, CTNNB1
22branching involved in ureteric bud morphogenesisGO:0016589.7FGF2, CTNNB1, MYC
23regulation of angiogenesisGO:0457659.6CTNNB1, FGF2
24male genitalia developmentGO:0305399.6BMP6, CTNNB1
25positive regulation of mesenchymal cell proliferationGO:0020539.6VEGFA, MYC, CTNNB1
26positive regulation of epithelial cell proliferationGO:0506799.6MYC, VEGFA, BMP6
27positive regulation of endothelial cell proliferationGO:0019389.6VEGFA, BMP6, FGF2
28platelet degranulationGO:0025769.6TGFB3, IGF2, VEGFA
29positive regulation of protein phosphorylationGO:0019349.5ENG, VEGFA, IGF2
30positive regulation of osteoblast differentiationGO:0456699.5BMP6, FGF2, CTNNB1
31positive regulation of protein secretionGO:0507149.4TGFB3, BMP6
32positive regulation of MAPK cascadeGO:0434109.4IGF2, KIT, CTNNB1
33positive regulation of cell divisionGO:0517819.3FGF2, TGFB3, IGF2, VEGFA
34phosphatidylinositol-mediated signalingGO:0480159.3PCNA, KIT, FGF2
35response to estradiolGO:0323559.3IGF2, CTNNB1, ESR1
36response to cadmium ionGO:0466869.2CTNNB1, PCNA
37negative regulation of transcription from RNA polymerase II promoterGO:0001229.1MYC, BMI1, ENG, VEGFA, CTNNB1
38positive regulation of transcription, DNA-templatedGO:0458939.0CTNNB1, CDH1, MYC, FGF2, TGFB3
39cellular response to mechanical stimulusGO:0712609.0CTNNB1, BMP6, IGF2, ENG
40positive regulation of cell proliferationGO:0082848.9IGF2, VEGFA, KIT, FGF2, MYC
41response to drugGO:0424938.7CTNNB1, CDH1, IGF2, MYC, ACTC1
42positive regulation of transcription from RNA polymerase II promoterGO:0459447.3VEGFA, IGF2, TGFB3, ESR1, MYC, BMP6

Molecular functions related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1type I transforming growth factor beta receptor bindingGO:03471310.2ENG, TGFB3
2type II transforming growth factor beta receptor bindingGO:00511410.1ENG, TGFB3
3transforming growth factor beta bindingGO:05043110.1ENG, TGFB3
4steroid bindingGO:0054969.8ESR1, PGR
5chemoattractant activityGO:0420569.6FGF2, VEGFA
6cytokine activityGO:0051258.9VEGFA, FGF2, BMP6
7identical protein bindingGO:0428028.6PCNA, VEGFA, TGFB3, ESR1
8growth factor activityGO:0080838.5BMP6, TGFB3, IGF2, FGF2, VEGFA
9protein bindingGO:0055155.3TGFB3, ZAP70, KIT, PCNA, BMI1, MYC

Products for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources for Juvenile Nasopharyngeal Angiofibroma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet