JNA
MCID: JVN033
MIFTS: 51

Juvenile Nasopharyngeal Angiofibroma (JNA) malady

Cancer diseases, Rare diseases categories

Summaries for Juvenile Nasopharyngeal Angiofibroma

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34MalaCards
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MalaCards: Juvenile Nasopharyngeal Angiofibroma, also known as JNA, is related to familial adenomatous polyposis and nasopharyngitis. An important gene associated with Juvenile Nasopharyngeal Angiofibroma is BMI1 (BMI1 polycomb ring finger oncogene), and among its related pathways are Angiogenesis and Tyrosine Kinases / Adaptors. The compounds everolimus and triphenylethylene have been mentioned in the context of this disorder. Affiliated tissues include endothelial and retina, and related mouse phenotypes are liver/biliary system and craniofacial.

Aliases & Classifications for Juvenile Nasopharyngeal Angiofibroma

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50Orphanet, 27ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Orphanet: 50 
Rare tumors


Aliases & Descriptions:

juvenile nasopharyngeal angiofibroma 50
jna 50


External Ids:

ICD10 via Orphanet27 D10.6

Related Diseases for Juvenile Nasopharyngeal Angiofibroma

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18GeneCards, 19GeneDecks
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Diseases related to Juvenile Nasopharyngeal Angiofibroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 135)
idRelated DiseaseScoreTop Affiliating Genes
1familial adenomatous polyposis30.8MYC, CDH1, CTNNB1
2nasopharyngitis11.5
3retinitis10.5
4endotheliitis10.5
5fibrous histiocytoma10.3
6central retinal artery occlusion10.3
7foster-kennedy syndrome10.3
8alopecia10.3
9esotropia10.3
10fibrosarcoma10.3
11histiocytoma10.3
12retinal artery occlusion10.3
13angiodysplasia10.1ENG
14carney triad10.1KIT
15cerebral meningioma10.1PGR
16hypoglycemic coma10.1IGF2
17spindle cell carcinoma10.1PGR, ACTC1
18dermatofibrosarcoma protuberans10.1ACTC1, KIT
19hereditary hemorrhagic telangiectasia10.1BMP6, ENG
20leiomyomatosis10.1PGR, ESR1
21gestational trophoblastic tumor10.1H19, PCNA
22prolymphocytic leukemia10.1MYC, ZAP70
23teratoma10.1ACTC1, H19, KIT
24telangiectasis10.1BMP6, ENG
25myelofibrosis10.1BMP6, FGF2
26progesterone resistance10.1ESR1, PGR
27embryonal cancer10.1IGF2, H19
28mammary paget's disease10.1PGR, ESR1
29diabetic macular edema10.1VEGFA
30mesoblastic nephroma10.1IGF2, KIT
31uterine sarcoma10.1ESR1, KIT
32bilateral breast cancer10.1PGR, ESR1
33follicular lymphoma10.1MYC, BMI1, ZAP70
34breast fibroadenoma10.1PGR, ESR1
35papilloma10.1ENG, PCNA, ACTC1
36li-fraumeni syndrome10.1PGR, ESR1
37gastrointestinal stromal tumor10.1KIT, PCNA, ACTC1
38middle ear cholesteatoma10.1PCNA, FGF2
39clear cell sarcoma10.1IGF2, KIT
40myoma10.1PGR, ESR1
41adenosarcoma10.1PGR, ESR1, ACTC1
42hemihypertrophy10.1IGF2, H19
43rhabdoid tumor10.1ACTC1, IGF2
44hypertrophic scars10.1TGFB3, BMP6, FGF2
45keloids10.1TGFB3, BMP6, FGF2
46hemangiopericytoma10.1IGF2, ACTC1
47uterine fibroid10.1ESR1, PGR
48corneal neovascularization10.1VEGFA, FGF2
49embryonal rhabdomyosarcoma10.1H19, ACTC1, IGF2
50benign meningioma10.1PCNA, PGR

Graphical network of the top 20 diseases related to Juvenile Nasopharyngeal Angiofibroma:



Diseases related to juvenile nasopharyngeal angiofibroma

Symptoms for Juvenile Nasopharyngeal Angiofibroma

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Drugs & Therapeutics for Juvenile Nasopharyngeal Angiofibroma

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Juvenile Nasopharyngeal Angiofibroma

Drug clinical trials:

Search ClinicalTrials for Juvenile Nasopharyngeal Angiofibroma

Search NIH Clinical Center for Juvenile Nasopharyngeal Angiofibroma

Search CenterWatch for Juvenile Nasopharyngeal Angiofibroma

Genetic Tests for Juvenile Nasopharyngeal Angiofibroma

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Anatomical Context for Juvenile Nasopharyngeal Angiofibroma

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34MalaCards
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MalaCards organs/tissues related to Juvenile Nasopharyngeal Angiofibroma:

34
Endothelial, Retina

Animal Models for Juvenile Nasopharyngeal Angiofibroma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Juvenile Nasopharyngeal Angiofibroma:

38 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.9CTNNB1, KIT, MYC, ESR1, VEGFA, IGF2
2MP:00053827.6IGF2, VEGFA, TGFB3, MYC, BMI1, KIT
3MP:00053917.6IGF2, VEGFA, TGFB3, BMI1, KIT, CTNNB1
4MP:00053887.5IGF2, VEGFA, TGFB3, ESR1, BMI1, KIT
5MP:00053717.5IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
6MP:00020067.3VEGFA, PGR, ESR1, MYC, BMI1, H19
7MP:00053697.1IGF2, VEGFA, PGR, ESR1, MYC, ACTC1
8MP:00053817.1ESR1, TGFB3, VEGFA, IGF2, MYC, BMI1
9MP:00028737.1VEGFA, TGFB3, PGR, MYC, ACTC1, BMI1
10MP:00107716.9ESR1, PGR, VEGFA, IGF2, MYC, KIT
11MP:00053866.8IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
12MP:00036316.7ESR1, TGFB3, VEGFA, IGF2, MYC, BMI1
13MP:00053806.6IGF2, VEGFA, TGFB3, PGR, ESR1, MYC
14MP:00030126.4ESR1, PGR, VEGFA, IGF2, MYC, H19
15MP:00053796.4ESR1, PGR, VEGFA, IGF2, MYC, BMI1
16MP:00053766.3ESR1, PGR, TGFB3, VEGFA, IGF2, MYC
17MP:00053856.3ESR1, PGR, TGFB3, VEGFA, IGF2, MYC
18MP:00053906.2FGF2, IGF2, VEGFA, TGFB3, PGR, ESR1
19MP:00053846.0MYC, ESR1, PGR, TGFB3, VEGFA, IGF2
20MP:00053976.0MYC, ESR1, PGR, VEGFA, IGF2, BMI1
21MP:00053876.0IGF2, VEGFA, PGR, ESR1, MYC, BMI1
22MP:00053895.8IGF2, VEGFA, PGR, ESR1, MYC, BMP6
23MP:00053785.5ACTC1, MYC, ESR1, VEGFA, IGF2, BMI1
24MP:00107685.2MYC, ESR1, PGR, TGFB3, VEGFA, IGF2

Publications for Juvenile Nasopharyngeal Angiofibroma

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53PubMed
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Articles related to Juvenile Nasopharyngeal Angiofibroma:

(show top 50)    (show all 251)
idTitleAuthorsYear
1
Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. (23878770)
2013
2
Tenascin-C, GLUT-1, and syndecan-2 expression in juvenile nasopharyngeal angiofibroma: correlations to vessel density and tumor stage. (22791513)
2013
3
Endonasal endoscopic management of juvenile nasopharyngeal angiofibroma without angiographic embolization. (23271032)
2013
4
Bilateral non-superselective embolization with particles under transient occlusion of the internal carotid artery in the management of juvenile nasopharyngeal angiofibroma: technical note. (22903329)
2012
5
Juvenile nasopharyngeal angiofibroma with intradural extension. (22030982)
2011
6
Role of Le Fort type I osteotomy approach in juvenile nasopharyngeal angiofibroma. (21880465)
2011
7
Endoscopically assisted intratumoral embolization of juvenile nasopharyngeal angiofibroma using Onyx. (21631195)
2011
8
The changing surgical management of juvenile nasopharyngeal angiofibroma. (20848119)
2011
9
Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma. (21492601)
2010
10
Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study. (22319699)
2010
11
Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). (19922097)
2009
12
Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. (19842877)
2009
13
Juvenile nasopharyngeal angiofibroma in a tertiary centre: ten-year experience. (19352568)
2009
14
Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence and proposal of a staging system. (18623035)
2008
15
Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. (19668408)
2008
16
Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. (19144296)
2008
17
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA). (18227724)
2008
18
Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. (17556070)
2007
19
Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. (17285972)
2006
20
Orbital involvement in juvenile nasopharyngeal angiofibroma: prevalence and treatment. (15266144)
2004
21
Tissue maturation during the growth of juvenile nasopharyngeal angiofibroma. (14763569)
2004
22
Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. (11238055)
2001
23
Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. (11374252)
2001
24
Immunolocalization of activated transforming growth factor beta1 in juvenile nasopharyngeal angiofibroma. (10864108)
2000
25
Juvenile nasopharyngeal angiofibroma. (10410346)
1999
26
Noradrenergic innervation of juvenile nasopharyngeal angiofibroma. (8024761)
1994
27
Radiation therapy as an alternative to surgery in the management of intracranial juvenile nasopharyngeal angiofibroma. (8300314)
1993
28
Surgical experience with juvenile nasopharyngeal angiofibroma. (1337963)
1992
29
Juvenile nasopharyngeal angiofibroma: a trap for the unwary. (1322461)
1992
30
Juvenile nasopharyngeal angiofibroma in a static population: the implications of misdiagnosis. (2178075)
1990
31
Preoperative embolisation in the management of juvenile nasopharyngeal angiofibroma. (2561258)
1989
32
The treatment of advanced juvenile nasopharyngeal angiofibroma. (2553648)
1989
33
Juvenile nasopharyngeal angiofibroma. (3025797)
1986
34
Juvenile nasopharyngeal angiofibroma treated by radiotherapy. (3005454)
1986
35
Juvenile nasopharyngeal angiofibroma: an unusual presentation in the oral cavity. (2989749)
1985
36
Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. (6327493)
1984
37
A few points in the management of juvenile nasopharyngeal angiofibroma. (6325570)
1984
38
Oronasal fistula--a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. (6308111)
1983
39
Juvenile nasopharyngeal angiofibroma--the preferred treatment. (6301001)
1983
40
Clinicopathologic conferences. Case 46, Part II: Juvenile nasopharyngeal angiofibroma. (6306189)
1983
41
Juvenile nasopharyngeal angiofibroma. (6256588)
1980
42
Juvenile nasopharyngeal angiofibroma. (6255615)
1980
43
Juvenile nasopharyngeal angiofibroma. A report of seven cases. (205902)
1978
44
Juvenile nasopharyngeal angiofibroma. (4344430)
1972
45
Juvenile nasopharyngeal angiofibroma. (4338568)
1972
46
Further experience in treatment of juvenile nasopharyngeal angiofibroma. (4305190)
1969
47
Juvenile nasopharyngeal angiofibroma. a theory of pathogenesis. (14442741)
1959
48
Sarcomatous transformation of a juvenile, nasopharyngeal angiofibroma. (13532703)
1958
49
Juvenile nasopharyngeal angiofibroma. (13087657)
1953
50
Juvenile Nasopharyngeal Angiofibroma. (17859097)
1948

Variations for Juvenile Nasopharyngeal Angiofibroma

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Expression for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

Search GEO for disease gene expression data for Juvenile Nasopharyngeal Angiofibroma.

Pathways for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources:
51PathCards, 5Cell Signaling Technology, 39NCBI BioSystems Database, 31KEGG, 61Thomson Reuters, 56Reactome, 58SinoBiological, 55R&D Systems, 13EMD Millipore, 54QIAGEN
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Pathways related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7FGF2, ENG, TGFB3
29.6KIT, ZAP70, FGF2
39.5VEGFA, TGFB3, FGF2
4
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy39
9.5CTNNB1, ACTC1, TGFB3
5
Show member pathways
9.5MYC, TGFB3, VEGFA
6
Show member pathways
Prolactin Signaling Pathway39
Development Prolactin receptor signaling61
Leptin signaling pathway39
9.5ZAP70, MYC, ESR1
7
Show member pathways
Cell cycle ESR1 regulation of G1 S transition61
Immune response MIF JAB1 signaling61
Cell cycle Cell cycle generic schema 61
9.5MYC, ESR1, PGR
8
Show member pathways
9.4BMP6, MYC, TGFB3
99.3ENG, MYC, ESR1, TGFB3
10
Show member pathways
Neurophysiological process Receptor mediated axon growth repulsion61
Pathogenic Escherichia coli infection39
9.3CTNNB1, CDH1, ACTC1
119.3ACTC1, CDH1, CTNNB1
129.2ESR1, MYC, CTNNB1
13
Show member pathways
9.2TGFB3, VEGFA, IGF2
14
Show member pathways
9.2PGR, ESR1, KIT, FGF2
15
Show member pathways
Development ERBB family signaling61
Development GDNF family signaling61
9.2CTNNB1, CDH1, MYC
169.2MYC, CDH1, CTNNB1
179.2CTNNB1, CDH1, MYC
189.1VEGFA, MYC, KIT, FGF2
199.0IGF2, ACTC1, KIT, FGF2
209.0CTNNB1, BMP6, VEGFA
219.0IGF2, MYC, CTNNB1
228.9CTNNB1, CDH1, MYC, TGFB3
238.8MYC, CDH1, CTNNB1, FGF2
248.8TGFB3, ESR1, MYC, ENG, CTNNB1
25
Show member pathways
Immune response IL 4 signaling pathway61
Signal transduction AKT signaling61
8.7PCNA, MYC, IGF2
26
Show member pathways
8.7VEGFA, TGFB3, MYC, BMP6, KIT
27
Show member pathways
Cell cycle39
8.6TGFB3, MYC, PCNA, CDH1
288.6IGF2, VEGFA, BMP6, FGF2
298.6TGFB3, MYC, PCNA, CTNNB1
30
Show member pathways
8.5IGF2, TGFB3, BMP6, ZAP70, FGF2
31
Show member pathways
8.5IGF2, TGFB3, BMP6, KIT, FGF2
32
Show member pathways
Signaling Pathways in Glioblastoma39
8.4FGF2, CTNNB1, CDH1, MYC, VEGFA
338.4TGFB3, MYC, BMP6, CDH1, CTNNB1
348.4VEGFA, ESR1, MYC, CDH1, CTNNB1
35
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
36
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
37
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
38
Show member pathways
8.2VEGFA, KIT, ZAP70, CDH1, CTNNB1, FGF2
39
Show member pathways
8.0IGF2, TGFB3, BMP6, KIT, CTNNB1, FGF2
407.9VEGFA, TGFB3, MYC, KIT, CDH1, CTNNB1
41
Show member pathways
7.9IGF2, TGFB3, MYC, BMP6, KIT, ZAP70
427.9IGF2, VEGFA, ESR1, MYC, CTNNB1, FGF2
43
Show member pathways
Signal transduction PTEN pathway61
7.8TGFB3, MYC, PCNA, KIT, CDH1, CTNNB1
44
Show member pathways
7.7IGF2, TGFB3, MYC, BMP6, KIT, CDH1
457.7VEGFA, ESR1, MYC, PCNA, CTNNB1, FGF2
46
Show member pathways
7.5IGF2, TGFB3, BMP6, KIT, CDH1, CTNNB1
47
Show member pathways
7.5IGF2, TGFB3, ESR1, MYC, BMP6, KIT
48
Show member pathways
7.3IGF2, VEGFA, PGR, ESR1, MYC, KIT
49
Show member pathways
7.1IGF2, TGFB3, ESR1, BMP6, KIT, CDH1
50
Show member pathways
6.5FGF2, IGF2, TGFB3, ESR1, MYC, BMP6

Compounds for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources:
46Novoseek, 52PharmGKB, 12DrugBank, 25HMDB, 62Tocris Bioscience, 30IUPHAR, 3BitterDB
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Compounds related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 198)
idCompoundScoreTop Affiliating Genes
1everolimus46 52 1211.3VEGFA, KIT, MYC, ESR1
2triphenylethylene469.2PGR, ESR1, BMP6
3trastuzumab46 52 1210.9VEGFA, PGR, ESR1, KIT, CTNNB1
4danazol46 25 1210.7PGR, PCNA, CDH1, ESR1
5docetaxel46 52 62 1211.6PGR, ESR1, CDH1, VEGFA, KIT, MYC
6methylcellulose468.6CDH1, KIT, IGF2, CTNNB1, FGF2
7geldanamycin46 52 62 1211.5CTNNB1, CDH1, ESR1, PGR, KIT, VEGFA
8hyaluronic acid46 259.5VEGFA, BMP6, FGF2, MYC, ENG, CDH1
9progestin468.5IGF2, VEGFA, TGFB3, CDH1, ESR1, PGR
10dfmo46 30 6210.2MYC, CDH1, CTNNB1, IGF2
11celecoxib46 62 30 52 25 1213.2VEGFA, PCNA, CDH1, CTNNB1, FGF2
12matrigel468.1VEGFA, FGF2, ACTC1, CTNNB1, CDH1, ENG
13retinoid468.1CDH1, MYC, ESR1, BMP6, CTNNB1, PGR
14ribonucleic acid468.1ACTC1, IGF2, BMP6, H19, KIT, MYC
15pd 98,059468.1CDH1, CTNNB1, BMP6, MYC, KIT, ZAP70
164-hydroxytamoxifen468.0TGFB3, IGF2, ESR1, MYC, BMP6, CTNNB1
17tgf beta1468.0FGF2, CTNNB1, CDH1, BMP6, TGFB3, IGF2
18steroid468.0ACTC1, KIT, H19, IGF2, TGFB3, PGR
19methotrexate52 46 129.9CDH1, PGR, ESR1, PCNA, KIT, BMP6
20gefitinib46 52 129.9ESR1, KIT, CDH1, CTNNB1, IGF2, FGF2
21mg 13246 628.9CDH1, VEGFA, ESR1, MYC, PCNA, CTNNB1
22suramin46 30 129.8VEGFA, BMP6, FGF2, IGF2, PCNA
23imatinib46 52 129.7IGF2, VEGFA, CTNNB1, ZAP70, KIT, BMP6
24rapamycin467.6BMP6, CDH1, MYC, CTNNB1, IGF2, VEGFA
25dihydrotestosterone46 30 25 1210.5BMP6, PGR, ESR1, CDH1, CTNNB1, FGF2
26doxorubicin46 52 129.4ENG, CDH1, PGR, VEGFA, KIT, ESR1
27indomethacin46 30 62 1210.4PCNA, IGF2, CDH1, MYC, BMP6, PGR
28phosphatidylinositol467.3FGF2, IGF2, MYC, BMP6, KIT, ZAP70
29agar467.3FGF2, CTNNB1, CDH1, ENG, H19, BMP6
30ly294002467.3IGF2, FGF2, MYC, CTNNB1, CDH1, BMP6
31glutamine467.2CTNNB1, KIT, BMP6, PGR, IGF2, CDH1
32cycloheximide467.2BMP6, IGF2, VEGFA, PGR, ESR1, MYC
33heparin46 30 25 1210.1ZAP70, IGF2, BMP6, FGF2, PCNA, VEGFA
34genistein46 30 62 3 25 1212.1FGF2, CTNNB1, CDH1, ZAP70, PCNA, VEGFA
35testosterone46 62 25 1210.0PCNA, ACTC1, KIT, CTNNB1, PGR, ESR1
36oligonucleotide467.0MYC, KIT, BMP6, PCNA, ZAP70, ENG
375fluorouracil466.9IGF2, VEGFA, TGFB3, PGR, ESR1, PCNA
38cisplatin46 52 62 129.8VEGFA, ESR1, MYC, BMP6, CDH1, CTNNB1
395-aza-2deoxycytidine466.7PGR, ESR1, MYC, BMP6, H19, PCNA
40thymidine46 257.7IGF2, TGFB3, MYC, BMP6, H19, PCNA
41alanine466.7FGF2, CTNNB1, CDH1, BMP6, MYC, PCNA
42tamoxifen46 52 30 129.5ESR1, MYC, VEGFA, IGF2, BMP6, PGR
43progesterone46 30 62 25 1210.3IGF2, CTNNB1, CDH1, ENG, KIT, PCNA
44tyrosine466.2CDH1, ENG, IGF2, VEGFA, TGFB3, FGF2
45paclitaxel46 52 127.9VEGFA, PGR, ESR1, MYC, BMP6, PCNA
46dexamethasone46 52 30 128.6FGF2, CTNNB1, CDH1, ENG, ZAP70, PCNA
47retinoic acid46 256.6CDH1, H19, BMP6, ACTC1, MYC, KIT
48paraffin465.5PGR, TGFB3, VEGFA, IGF2, ESR1, MYC
49vegf465.2PCNA, BMP6, ACTC1, MYC, ESR1, PGR
50estrogen465.0ENG, FGF2, IGF2, KIT, PCNA, BMP6

GO Terms for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources:
17Gene Ontology
See all sources

Cellular components related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:0163429.4CTNNB1, CDH1
2cytoplasmic side of plasma membraneGO:0098989.3KIT, CDH1, CTNNB1
3platelet alpha granule lumenGO:0310939.3TGFB3, VEGFA, IGF2
4cell surfaceGO:0099869.1CDH1, ENG, TGFB3, VEGFA
5nucleoplasmGO:0056547.9PGR, ESR1, MYC, BMI1, PCNA, CTNNB1
6extracellular spaceGO:0056157.8FGF2, ENG, KIT, BMP6, ACTC1, TGFB3
7cytoplasmGO:0057376.5VEGFA, ACTC1, BMI1, BMP6, PCNA, ZAP70

Biological processes related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 42)
idNameGO IDScoreTop Affiliating Genes
1detection of hypoxiaGO:07048310.4ENG, TGFB3
2central nervous system vasculogenesisGO:02200910.1CTNNB1, ENG
3cell migration involved in sprouting angiogenesisGO:00204210.0FGF2, VEGFA
4positive regulation of collagen biosynthetic processGO:03296710.0TGFB3, ENG
5positive regulation of blood vessel endothelial cell migrationGO:04353610.0FGF2, VEGFA
6mammary gland alveolus developmentGO:06074910.0ESR1, VEGFA
7activation of MAPK activityGO:00018710.0TGFB3, KIT, FGF2
8transforming growth factor beta receptor signaling pathwayGO:00717910.0TGFB3, MYC, ENG
9positive regulation of fibroblast proliferationGO:0481469.9ESR1, MYC, BMI1
10artery morphogenesisGO:0488449.9ENG, VEGFA
11positive regulation of phospholipase C activityGO:0108639.9ESR1, KIT, FGF2
12positive regulation of pathway-restricted SMAD protein phosphorylationGO:0108629.9TGFB3, BMP6, ENG
13regulation of protein localization to cell surfaceGO:20000089.9CDH1, CTNNB1
14cellular response to indole-3-methanolGO:0716819.9CDH1, CTNNB1
15digestive tract developmentGO:0485659.9KIT, TGFB3
16positive regulation of gene expressionGO:0106289.8VEGFA, KIT, ENG
17response to hypoxiaGO:0016669.8VEGFA, TGFB3, ENG
18positive regulation of neuroblast proliferationGO:0020529.8CTNNB1, VEGFA
19positive regulation of endothelial cell differentiationGO:0456039.8CTNNB1, BMP6
20positive regulation of protein secretionGO:0507149.7BMP6, TGFB3
21patterning of blood vesselsGO:0015699.7VEGFA, ENG, CTNNB1
22regulation of angiogenesisGO:0457659.7CTNNB1, FGF2
23branching involved in ureteric bud morphogenesisGO:0016589.7FGF2, CTNNB1, MYC
24male genitalia developmentGO:0305399.6CTNNB1, BMP6
25positive regulation of mesenchymal cell proliferationGO:0020539.6VEGFA, MYC, CTNNB1
26positive regulation of epithelial cell proliferationGO:0506799.6BMP6, MYC, VEGFA
27positive regulation of phosphatidylinositol 3-kinase activityGO:0435529.6FGF2, KIT
28positive regulation of endothelial cell proliferationGO:0019389.6FGF2, BMP6, VEGFA
29platelet degranulationGO:0025769.6TGFB3, VEGFA, IGF2
30positive regulation of protein phosphorylationGO:0019349.5ENG, VEGFA, IGF2
31positive regulation of osteoblast differentiationGO:0456699.5BMP6, CTNNB1, FGF2
32positive regulation of MAPK cascadeGO:0434109.4IGF2, KIT, CTNNB1
33positive regulation of cell divisionGO:0517819.3FGF2, TGFB3, VEGFA, IGF2
34phosphatidylinositol-mediated signalingGO:0480159.3FGF2, KIT, PCNA
35response to estradiolGO:0323559.3IGF2, ESR1, CTNNB1
36response to cadmium ionGO:0466869.3CTNNB1, PCNA
37negative regulation of transcription from RNA polymerase II promoterGO:0001229.1CTNNB1, ENG, BMI1, MYC, VEGFA
38positive regulation of transcription, DNA-templatedGO:0458939.0TGFB3, MYC, CDH1, CTNNB1, FGF2
39cellular response to mechanical stimulusGO:0712609.0IGF2, BMP6, ENG, CTNNB1
40positive regulation of cell proliferationGO:0082848.9FGF2, KIT, MYC, VEGFA, IGF2
41response to drugGO:0424938.7CTNNB1, CDH1, ACTC1, MYC, IGF2
42positive regulation of transcription from RNA polymerase II promoterGO:0459447.3FGF2, IGF2, VEGFA, TGFB3, ESR1, MYC

Molecular functions related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1type I transforming growth factor beta receptor bindingGO:03471310.2TGFB3, ENG
2type II transforming growth factor beta receptor bindingGO:00511410.1TGFB3, ENG
3transforming growth factor beta bindingGO:05043110.1ENG, TGFB3
4steroid bindingGO:0054969.8ESR1, PGR
5chemoattractant activityGO:0420569.6FGF2, VEGFA
6cytokine activityGO:0051258.9FGF2, BMP6, VEGFA
7identical protein bindingGO:0428028.6VEGFA, TGFB3, ESR1, PCNA
8growth factor activityGO:0080838.5IGF2, VEGFA, TGFB3, BMP6, FGF2
9protein bindingGO:0055155.3FGF2, IGF2, VEGFA, TGFB3, PGR, ESR1

Products for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources for Juvenile Nasopharyngeal Angiofibroma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet