MCID: JVN033
MIFTS: 41

Juvenile Nasopharyngeal Angiofibroma malady

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Juvenile Nasopharyngeal Angiofibroma

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Sources:
51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Juvenile Nasopharyngeal Angiofibroma:

Name: Juvenile Nasopharyngeal Angiofibroma 51
 
Jna 51

Classifications:

Orphanet: 51 
Rare tumors


External Ids:

Orphanet51 289596
ICD10 via Orphanet28 D10.6

Summaries for Juvenile Nasopharyngeal Angiofibroma

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MalaCards based summary: Juvenile Nasopharyngeal Angiofibroma, also known as jna, is related to nasopharyngitis and syringoma. An important gene associated with Juvenile Nasopharyngeal Angiofibroma is PCNA (Proliferating Cell Nuclear Antigen), and among its related pathways are Th17 Differentiation Pathway and IL27-mediated signaling events. Affiliated tissues include breast, prostate and thyroid, and related mouse phenotypes are no phenotypic analysis and endocrine/exocrine gland.

Related Diseases for Juvenile Nasopharyngeal Angiofibroma

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Diseases related to Juvenile Nasopharyngeal Angiofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 111)
idRelated DiseaseScoreTop Affiliating Genes
1nasopharyngitis11.2
2syringoma10.8ESR1, PGR
3endocrine organ benign neoplasm10.8ESR1, PGR
4cervical benign neoplasm10.8ESR1, PGR
5large bowel leiomyoma10.8ESR1, PGR
6bile duct cystadenoma10.8ESR1, PGR
7glaucoma iridogoniodysgenesia10.8ESR1, PGR
8venous tributary occlusion of retina10.7ESR1, PGR
9deafness, autosomal dominant 8/1210.7ESR1, PGR
10peroneal nerve paralysis10.7ESR1, PGR
11situs inversus10.7ESR1, PGR
12vulvar squamous papilloma10.7ESR1, PGR
13childhood choriocarcinoma of the ovary10.7ESR1, PGR
14ureter adenocarcinoma10.7ESR1, PGR
15dental pulp calcification10.7ESR1, PGR
16spondylitis10.7ESR1, PGR
17vulvar alveolar soft part sarcoma10.7ESR1, PGR
18pancreatic cystadenoma10.7PGR, VEGFA
19rectum mucinous adenocarcinoma10.7ESR1, PGR
20childhood mediastinal neurogenic tumor10.7ESR1, PGR
21apocrine adenosis of breast10.7ESR1, PGR
22retroperitoneal sarcoma10.7ESR1, PGR
23benign multicystic peritoneal mesothelioma10.7ACTC1, PGR
24uterine corpus adenosarcoma10.7ESR1, PGR
25renal pelvis squamous cell carcinoma10.7ESR1, PGR
26sciatic neuropathy10.6ESR1, PGR
27adult mesoblastic nephroma10.6ACTC1, PGR
28intraventricular meningioma10.6ESR1, PGR
29ovarian mucinous cystadenocarcinoma10.6ACTC1, PCNA
30large cell acanthoma10.6ESR1, PGR
31primary gastrointestinal melanoma10.6MYC, VEGFA
32breast metaplastic carcinoma10.6ESR1, PGR
33internal auditory canal lipoma10.6ESR1, PGR
34prostatic cyst10.5ESR1, PCNA, PGR
35adenosarcoma of the uterus10.5ESR1, PGR, VEGFA
36ovary epithelial cancer10.5ESR1, PGR, VEGFA
37ovarian wilms' cancer10.5ESR1, PGR, VEGFA
38leptospirosis10.5ESR1, PGR, VEGFA
39deep leiomyoma10.5ACTC1, PCNA, PGR
40omsk hemorrhagic fever10.5ESR1, VEGFA
41microinvasive gastric cancer10.5PCNA, VEGFA
42suppurative thyroiditis10.5ESR1, PGR
43thymus lipoma10.5ACTC1, ESR1, PGR
44exocervical carcinoma10.5ESR1, PGR, VEGFA
45autoimmune lymphoproliferative syndrome10.4ESR1, PCNA, PGR
46senile angioma10.4ENG, VEGFA
47paranoid schizophrenia10.4TLR9, VEGFA
48sclerosing bone dysplasia mental retardation10.4ACTC1, FGF2
49ovarian clear cell adenocarcinoma10.4ESR1, PGR
50chronic venous leg ulcers10.4FGF2, VEGFA

Graphical network of the top 20 diseases related to Juvenile Nasopharyngeal Angiofibroma:



Diseases related to juvenile nasopharyngeal angiofibroma

Symptoms for Juvenile Nasopharyngeal Angiofibroma

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Drugs & Therapeutics for Juvenile Nasopharyngeal Angiofibroma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Juvenile Nasopharyngeal Angiofibroma

Genetic Tests for Juvenile Nasopharyngeal Angiofibroma

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Anatomical Context for Juvenile Nasopharyngeal Angiofibroma

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MalaCards organs/tissues related to Juvenile Nasopharyngeal Angiofibroma:

33
Breast, Prostate, Thyroid, Ovary, Lung, Endothelial, Retina

Animal Models for Juvenile Nasopharyngeal Angiofibroma or affiliated genes

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MGI Mouse Phenotypes related to Juvenile Nasopharyngeal Angiofibroma:

38 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.6ESR1, KIT, MYC, PCNA, PGR, VEGFA
2MP:00053798.3ESR1, KIT, MYC, PCNA, PGR, TLR3
3MP:00028738.1ACTC1, ENG, ESR1, KIT, MYC, PGR
4MP:00020067.9ESR1, FGF2, KIT, MYC, PGR, TLR3
5MP:00053907.3BMP6, ESR1, FGF2, KIT, MYC, PGR
6MP:00053877.2ESR1, KIT, MYC, PCNA, PGR, TLR3
7MP:00053847.2ACTC1, ESR1, FGF2, KIT, MYC, PGR
8MP:00053897.1BMP6, ESR1, FGF2, KIT, MYC, PCNA
9MP:00053696.9ACTC1, ENG, ESR1, FGF2, KIT, MYC
10MP:00053856.8ACTC1, ENG, ESR1, FGF2, KIT, MYC
11MP:00053766.2ACTC1, ENG, ESR1, FGF2, KIT, MYC
12MP:00053976.0ENG, ESR1, FGF2, KIT, MYC, PCNA
13MP:00107685.9ACTC1, ENG, ESR1, FGF2, KIT, MYC

Publications for Juvenile Nasopharyngeal Angiofibroma

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Articles related to Juvenile Nasopharyngeal Angiofibroma:

(show top 50)    (show all 286)
idTitleAuthorsYear
1
Changing trends in the incidence of juvenile nasopharyngeal angiofibroma: seven decades of experience at King George's Medical University, Lucknow, India. (26864451)
2016
2
Endoscopic graduated multiangle, multicorridor resection of juvenile nasopharyngeal angiofibroma: an individualized, tailored, multicorridor skull base approach. (26566205)
2015
3
Bilateral, independent juvenile nasopharyngeal angiofibroma: case report. (26314415)
2015
4
Microspheres embolization of juvenile nasopharyngeal angiofibroma in an adult. (25437676)
2014
5
Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. (23878770)
2013
6
Tenascin-C, GLUT-1, and syndecan-2 expression in juvenile nasopharyngeal angiofibroma: correlations to vessel density and tumor stage. (22791513)
2013
7
Endonasal endoscopic management of juvenile nasopharyngeal angiofibroma without angiographic embolization. (23271032)
2013
8
Bilateral non-superselective embolization with particles under transient occlusion of the internal carotid artery in the management of juvenile nasopharyngeal angiofibroma: technical note. (22903329)
2012
9
Juvenile nasopharyngeal angiofibroma with intradural extension. (22030982)
2011
10
Role of Le Fort type I osteotomy approach in juvenile nasopharyngeal angiofibroma. (21880465)
2011
11
Endoscopically assisted intratumoral embolization of juvenile nasopharyngeal angiofibroma using Onyx. (21631195)
2011
12
The changing surgical management of juvenile nasopharyngeal angiofibroma. (20848119)
2011
13
Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma. (21492601)
2010
14
Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study. (22319699)
2010
15
Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). (19922097)
2009
16
Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence and proposal of a staging system. (18623035)
2008
17
Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. (19668408)
2008
18
Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. (19144296)
2008
19
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA). (18227724)
2008
20
Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. (17556070)
2007
21
Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. (17285972)
2006
22
Orbital involvement in juvenile nasopharyngeal angiofibroma: prevalence and treatment. (15266144)
2004
23
Tissue maturation during the growth of juvenile nasopharyngeal angiofibroma. (14763569)
2004
24
Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. (11238055)
2001
25
Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. (11374252)
2001
26
Immunolocalization of activated transforming growth factor beta1 in juvenile nasopharyngeal angiofibroma. (10864108)
2000
27
Juvenile nasopharyngeal angiofibroma. (10410346)
1999
28
Surgical experience with juvenile nasopharyngeal angiofibroma. (1337963)
1992
29
Juvenile nasopharyngeal angiofibroma: a trap for the unwary. (1322461)
1992
30
Juvenile nasopharyngeal angiofibroma in a static population: the implications of misdiagnosis. (2178075)
1990
31
Preoperative embolisation in the management of juvenile nasopharyngeal angiofibroma. (2561258)
1989
32
The treatment of advanced juvenile nasopharyngeal angiofibroma. (2553648)
1989
33
Juvenile nasopharyngeal angiofibroma. (3025797)
1986
34
Juvenile nasopharyngeal angiofibroma treated by radiotherapy. (3005454)
1986
35
Juvenile nasopharyngeal angiofibroma: an unusual presentation in the oral cavity. (2989749)
1985
36
Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. (6327493)
1984
37
A few points in the management of juvenile nasopharyngeal angiofibroma. (6325570)
1984
38
Oronasal fistula--a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. (6308111)
1983
39
Juvenile nasopharyngeal angiofibroma--the preferred treatment. (6301001)
1983
40
Clinicopathologic conferences. Case 46, Part II: Juvenile nasopharyngeal angiofibroma. (6306189)
1983
41
Juvenile nasopharyngeal angiofibroma. (6256588)
1980
42
Juvenile nasopharyngeal angiofibroma. (6255615)
1980
43
Juvenile nasopharyngeal angiofibroma. A report of seven cases. (205902)
1978
44
Juvenile nasopharyngeal angiofibroma. (4344430)
1972
45
Juvenile nasopharyngeal angiofibroma. (4338568)
1972
46
Further experience in treatment of juvenile nasopharyngeal angiofibroma. (4305190)
1969
47
Juvenile nasopharyngeal angiofibroma. a theory of pathogenesis. (14442741)
1959
48
Sarcomatous transformation of a juvenile, nasopharyngeal angiofibroma. (13532703)
1958
49
Juvenile nasopharyngeal angiofibroma. (13087657)
1953
50
Juvenile Nasopharyngeal Angiofibroma. (17859097)
1948

Variations for Juvenile Nasopharyngeal Angiofibroma

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Expression for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Search GEO for disease gene expression data for Juvenile Nasopharyngeal Angiofibroma.

Pathways for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Pathways related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.4TLR3, TLR7, TLR9
2
Show member pathways
9.4TLR3, TLR7, TLR9
3
Show member pathways
9.4TLR3, TLR7, TLR9
49.4TLR3, TLR7, TLR9
59.3ENG, ESR1, MYC
69.3FGF2, MYC, VEGFA
7
Show member pathways
9.2PCNA, TLR3, TLR7, TLR9
89.1BMI1, FGF2, VEGFA
99.1BMP6, FGF2, VEGFA
109.1BMI1, FGF2, MYC
119.0ESR1, FGF2, MYC, VEGFA
129.0KIT, TLR7, TLR9
13
Show member pathways
8.8MYC, PCNA, TLR3, TLR7, TLR9
148.8BMI1, FGF2, MYC, VEGFA
158.8MYC, TLR3, TLR7, TLR9, VEGFA
168.7ESR1, FGF2, MYC, PCNA, VEGFA
178.7ACTC1, FGF2, KIT
188.4FGF2, KIT, MYC, VEGFA
198.4FGF2, KIT, MYC, VEGFA
20
Show member pathways
8.2BMP6, FGF2, TLR3, TLR7, TLR9
218.0BMP6, ENG, FGF2, KIT

GO Terms for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Biological processes related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interferon-beta biosynthetic processGO:004535910.5TLR3, TLR9
2positive regulation of interferon-beta productionGO:003272810.4TLR3, TLR9
3positive regulation of mesenchymal cell proliferationGO:000205310.4MYC, VEGFA
4I-kappaB phosphorylationGO:000725210.4TLR3, TLR9
5positive regulation of interleukin-12 productionGO:003273510.4TLR3, TLR9
6positive regulation of toll-like receptor signaling pathwayGO:003412310.3TLR3, TLR9
7cell migration involved in sprouting angiogenesisGO:000204210.3FGF2, VEGFA
8patterning of blood vesselsGO:000156910.3ENG, VEGFA
9artery morphogenesisGO:004884410.2ENG, VEGFA
10positive regulation of blood vessel endothelial cell migrationGO:004353610.2FGF2, VEGFA
11microglial cell activationGO:000177410.1TLR3, TLR7
12positive regulation of NF-kappaB import into nucleusGO:004234610.1TLR3, TLR7, TLR9
13positive regulation of interleukin-8 productionGO:00327579.9TLR3, TLR7, TLR9
14toll-like receptor signaling pathwayGO:00022249.8TLR3, TLR7, TLR9
15positive regulation of protein phosphorylationGO:00019349.6FGF2, TLR3, VEGFA
16positive regulation of phosphatidylinositol 3-kinase activityGO:00435529.4FGF2, KIT
17positive regulation of angiogenesisGO:00457669.4ENG, FGF2, VEGFA
18positive regulation of phospholipase C activityGO:00108639.3ESR1, FGF2, KIT
19negative regulation of transcription from RNA polymerase II promoterGO:00001229.1BMI1, BMP6, ESR1, VEGFA
20angiogenesisGO:00015259.1ENG, FGF2, VEGFA
21inflammatory responseGO:00069548.7BMP6, KIT, TLR3, TLR7
22innate immune responseGO:00450877.9FGF2, KIT, TLR3, TLR7, TLR9
23positive regulation of transcription from RNA polymerase II promoterGO:00459447.8BMP6, ENG, ESR1, FGF2, MYC, VEGFA
24positive regulation of gene expressionGO:00106287.8FGF2, KIT, TLR3, TLR9, VEGFA

Sources for Juvenile Nasopharyngeal Angiofibroma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet