MCID: JVN033
MIFTS: 52

Juvenile Nasopharyngeal Angiofibroma malady

Cancer diseases, Rare diseases categories

Summaries for Juvenile Nasopharyngeal Angiofibroma

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MalaCards based summary: Juvenile Nasopharyngeal Angiofibroma, also known as jna, is related to nasopharyngitis and endotheliitis. An important gene associated with Juvenile Nasopharyngeal Angiofibroma is BMI1 (BMI1 polycomb ring finger oncogene), and among its related pathways are Angiogenesis and Tyrosine Kinases / Adaptors. The compounds everolimus and triphenylethylene have been mentioned in the context of this disorder. Affiliated tissues include endothelial and retina, and related mouse phenotypes are liver/biliary system and craniofacial.

Aliases & Classifications for Juvenile Nasopharyngeal Angiofibroma

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Sources:
49Orphanet, 28ICD10 via Orphanet
See all sources

Juvenile Nasopharyngeal Angiofibroma, Aliases & Descriptions:

Name: Juvenile Nasopharyngeal Angiofibroma 49
 
Jna 49


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Orphanet: 49 
Rare tumors


External Ids:

Orphanet49 289596
ICD10 via Orphanet28 D10.6

Related Diseases for Juvenile Nasopharyngeal Angiofibroma

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Diseases related to Juvenile Nasopharyngeal Angiofibroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 136)
idRelated DiseaseScoreTop Affiliating Genes
1nasopharyngitis11.5
2endotheliitis10.6
3retinitis10.5
4alopecia10.3
5fibrous histiocytoma10.3
6central retinal artery occlusion10.3
7foster-kennedy syndrome10.3
8esotropia10.3
9fibrosarcoma10.3
10histiocytoma10.3
11retinal artery occlusion10.3
12angiodysplasia10.1ENG
13carney triad10.1KIT
14cerebral meningioma10.1PGR
15hypoglycemic coma10.1IGF2
16spindle cell carcinoma10.0ACTC1, PGR
17dermatofibrosarcoma protuberans10.0ACTC1, KIT
18hereditary hemorrhagic telangiectasia10.0BMP6, ENG
19leiomyomatosis10.0ESR1, PGR
20gestational trophoblastic tumor10.0PCNA, H19
21teratoma10.0H19, ACTC1, KIT
22prolymphocytic leukemia10.0MYC, ZAP70
23telangiectasis10.0BMP6, ENG
24myelofibrosis10.0BMP6, FGF2
25progesterone resistance10.0ESR1, PGR
26embryonal cancer10.0H19, IGF2
27diabetic macular edema10.0VEGFA
28mammary paget's disease10.0ESR1, PGR
29uterine sarcoma10.0KIT, ESR1
30mesoblastic nephroma10.0IGF2, KIT
31bilateral breast cancer10.0PGR, ESR1
32follicular lymphoma10.0MYC, BMI1, ZAP70
33breast fibroadenoma10.0PGR, ESR1
34chronic myocardial ischemia10.0FGF2, VEGFA
35papilloma10.0ENG, PCNA, ACTC1
36gastrointestinal stromal tumor10.0PCNA, ACTC1, KIT
37middle ear cholesteatoma10.0FGF2, PCNA
38breast disease10.0PGR, ESR1
39clear cell sarcoma10.0IGF2, KIT
40hemi 3 syndrome10.0IGF2, H19
41myoma10.0ESR1, PGR
42adenosarcoma10.0PGR, ACTC1, ESR1
43hypertrophic scars10.0TGFB3, BMP6, FGF2
44rhabdoid tumor10.0IGF2, ACTC1
45corneal neovascularization10.0VEGFA, FGF2
46uterine fibroid10.0ESR1, PGR
47keloids10.0BMP6, FGF2, TGFB3
48hemangiopericytoma10.0ACTC1, IGF2
49embryonal rhabdomyosarcoma10.0H19, ACTC1, IGF2
50benign meningioma10.0PCNA, PGR

Graphical network of the top 20 diseases related to Juvenile Nasopharyngeal Angiofibroma:



Diseases related to juvenile nasopharyngeal angiofibroma

Symptoms for Juvenile Nasopharyngeal Angiofibroma

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Drugs & Therapeutics for Juvenile Nasopharyngeal Angiofibroma

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Drug clinical trials:

Search ClinicalTrials for Juvenile Nasopharyngeal Angiofibroma

Search NIH Clinical Center for Juvenile Nasopharyngeal Angiofibroma

Genetic Tests for Juvenile Nasopharyngeal Angiofibroma

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Anatomical Context for Juvenile Nasopharyngeal Angiofibroma

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MalaCards organs/tissues related to Juvenile Nasopharyngeal Angiofibroma:

33
Endothelial, Retina

Animal Models for Juvenile Nasopharyngeal Angiofibroma or affiliated genes

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MGI Mouse Phenotypes related to Juvenile Nasopharyngeal Angiofibroma:

37 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.9CTNNB1, KIT, MYC, ESR1, VEGFA, IGF2
2MP:00053827.6MYC, TGFB3, BMI1, KIT, CTNNB1, VEGFA
3MP:00053917.6FGF2, CTNNB1, KIT, BMI1, TGFB3, VEGFA
4MP:00053887.5ESR1, VEGFA, ZAP70, IGF2, KIT, BMI1
5MP:00053717.5IGF2, TGFB3, KIT, BMI1, MYC, ESR1
6MP:00020067.3FGF2, CDH1, BMI1, VEGFA, PGR, ESR1
7MP:00053697.1VEGFA, ACTC1, KIT, ENG, CTNNB1, IGF2
8MP:00053817.1CTNNB1, H19, CDH1, KIT, MYC, VEGFA
9MP:00028737.1KIT, H19, BMI1, MYC, PGR, TGFB3
10MP:00107716.9IGF2, KIT, PGR, VEGFA, ESR1, MYC
11MP:00053866.8MYC, TGFB3, FGF2, CTNNB1, KIT, BMI1
12MP:00036316.7ESR1, VEGFA, TGFB3, FGF2, CTNNB1, ENG
13MP:00053806.6PGR, KIT, H19, MYC, ESR1, TGFB3
14MP:00030126.4IGF2, VEGFA, PGR, MYC, H19, PCNA
15MP:00053796.4VEGFA, IGF2, MYC, PCNA, ESR1, PGR
16MP:00053766.3VEGFA, FGF2, CTNNB1, CDH1, ENG, KIT
17MP:00053856.3BMI1, KIT, ENG, CDH1, CTNNB1, FGF2
18MP:00053906.2TGFB3, BMI1, BMP6, H19, KIT, ZAP70
19MP:00053846.0H19, BMI1, KIT, ENG, CDH1, CTNNB1
20MP:00053976.0FGF2, CTNNB1, ENG, ZAP70, KIT, PCNA
21MP:00053876.0ESR1, PGR, CTNNB1, VEGFA, MYC, BMI1
22MP:00053895.8VEGFA, PGR, ESR1, KIT, CDH1, PCNA
23MP:00053785.5ACTC1, CTNNB1, CDH1, ENG, IGF2, VEGFA
24MP:00107685.2ESR1, MYC, ACTC1, BMI1, H19, PCNA

Publications for Juvenile Nasopharyngeal Angiofibroma

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Articles related to Juvenile Nasopharyngeal Angiofibroma:

(show top 50)    (show all 264)
idTitleAuthorsYear
1
Microspheres embolization of juvenile nasopharyngeal angiofibroma in an adult. (25437676)
2014
2
Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. (23878770)
2013
3
Tenascin-C, GLUT-1, and syndecan-2 expression in juvenile nasopharyngeal angiofibroma: correlations to vessel density and tumor stage. (22791513)
2013
4
Endonasal endoscopic management of juvenile nasopharyngeal angiofibroma without angiographic embolization. (23271032)
2013
5
Bilateral non-superselective embolization with particles under transient occlusion of the internal carotid artery in the management of juvenile nasopharyngeal angiofibroma: technical note. (22903329)
2012
6
Juvenile nasopharyngeal angiofibroma with intradural extension. (22030982)
2011
7
Role of Le Fort type I osteotomy approach in juvenile nasopharyngeal angiofibroma. (21880465)
2011
8
Endoscopically assisted intratumoral embolization of juvenile nasopharyngeal angiofibroma using Onyx. (21631195)
2011
9
The changing surgical management of juvenile nasopharyngeal angiofibroma. (20848119)
2011
10
Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma. (21492601)
2010
11
Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study. (22319699)
2010
12
Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). (19922097)
2009
13
Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. (19842877)
2009
14
Juvenile nasopharyngeal angiofibroma in a tertiary centre: ten-year experience. (19352568)
2009
15
Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence and proposal of a staging system. (18623035)
2008
16
Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. (19668408)
2008
17
Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. (19144296)
2008
18
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA). (18227724)
2008
19
Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. (17285972)
2006
20
Orbital involvement in juvenile nasopharyngeal angiofibroma: prevalence and treatment. (15266144)
2004
21
Tissue maturation during the growth of juvenile nasopharyngeal angiofibroma. (14763569)
2004
22
Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. (11238055)
2001
23
Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. (11374252)
2001
24
Immunolocalization of activated transforming growth factor beta1 in juvenile nasopharyngeal angiofibroma. (10864108)
2000
25
Juvenile nasopharyngeal angiofibroma. (10410346)
1999
26
Noradrenergic innervation of juvenile nasopharyngeal angiofibroma. (8024761)
1994
27
Radiation therapy as an alternative to surgery in the management of intracranial juvenile nasopharyngeal angiofibroma. (8300314)
1993
28
Surgical experience with juvenile nasopharyngeal angiofibroma. (1337963)
1992
29
Juvenile nasopharyngeal angiofibroma: a trap for the unwary. (1322461)
1992
30
Juvenile nasopharyngeal angiofibroma in a static population: the implications of misdiagnosis. (2178075)
1990
31
Preoperative embolisation in the management of juvenile nasopharyngeal angiofibroma. (2561258)
1989
32
The treatment of advanced juvenile nasopharyngeal angiofibroma. (2553648)
1989
33
Juvenile nasopharyngeal angiofibroma. (3025797)
1986
34
Juvenile nasopharyngeal angiofibroma treated by radiotherapy. (3005454)
1986
35
Juvenile nasopharyngeal angiofibroma: an unusual presentation in the oral cavity. (2989749)
1985
36
Postirradiation malignant fibrous histiocytoma arising in juvenile nasopharyngeal angiofibroma and producing alpha-1-antitrypsin. (6327493)
1984
37
A few points in the management of juvenile nasopharyngeal angiofibroma. (6325570)
1984
38
Oronasal fistula--a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. (6308111)
1983
39
Juvenile nasopharyngeal angiofibroma--the preferred treatment. (6301001)
1983
40
Clinicopathologic conferences. Case 46, Part II: Juvenile nasopharyngeal angiofibroma. (6306189)
1983
41
Juvenile nasopharyngeal angiofibroma. (6256588)
1980
42
Juvenile nasopharyngeal angiofibroma. (6255615)
1980
43
Juvenile nasopharyngeal angiofibroma. A report of seven cases. (205902)
1978
44
Juvenile nasopharyngeal angiofibroma. (4344430)
1972
45
Juvenile nasopharyngeal angiofibroma. (4338568)
1972
46
Further experience in treatment of juvenile nasopharyngeal angiofibroma. (4305190)
1969
47
Juvenile nasopharyngeal angiofibroma. a theory of pathogenesis. (14442741)
1959
48
Sarcomatous transformation of a juvenile, nasopharyngeal angiofibroma. (13532703)
1958
49
Juvenile nasopharyngeal angiofibroma. (13087657)
1953
50
Juvenile Nasopharyngeal Angiofibroma. (17859097)
1948

Variations for Juvenile Nasopharyngeal Angiofibroma

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Expression for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Search GEO for disease gene expression data for Juvenile Nasopharyngeal Angiofibroma.

Pathways for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Pathways related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7FGF2, ENG, TGFB3
29.6KIT, ZAP70, FGF2
39.5VEGFA, TGFB3, FGF2
4
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy38
9.5CTNNB1, ACTC1, TGFB3
5
Show member pathways
9.5MYC, TGFB3, VEGFA
6
Show member pathways
Prolactin Signaling Pathway38
Development Prolactin receptor signaling60
Leptin signaling pathway38
9.5ZAP70, MYC, ESR1
7
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.5MYC, ESR1, PGR
8
Show member pathways
9.4BMP6, MYC, TGFB3
99.3ENG, MYC, ESR1, TGFB3
10
Show member pathways
Neurophysiological process Receptor mediated axon growth repulsion60
Pathogenic Escherichia coli infection38
9.3CTNNB1, CDH1, ACTC1
119.3ACTC1, CDH1, CTNNB1
129.2ESR1, MYC, CTNNB1
13
Show member pathways
9.2TGFB3, VEGFA, IGF2
14
Show member pathways
9.2PGR, ESR1, KIT, FGF2
15
Show member pathways
Development ERBB family signaling60
Development GDNF family signaling60
9.2CTNNB1, CDH1, MYC
169.2MYC, CDH1, CTNNB1
179.2CTNNB1, CDH1, MYC
189.1VEGFA, MYC, KIT, FGF2
199.0IGF2, ACTC1, KIT, FGF2
209.0CTNNB1, BMP6, VEGFA
219.0IGF2, MYC, CTNNB1
228.9CTNNB1, CDH1, MYC, TGFB3
238.8MYC, CDH1, CTNNB1, FGF2
248.8TGFB3, ESR1, MYC, ENG, CTNNB1
25
Show member pathways
Immune response IL 4 signaling pathway60
Signal transduction AKT signaling60
8.7PCNA, MYC, IGF2
26
Show member pathways
8.7VEGFA, TGFB3, MYC, BMP6, KIT
27
Show member pathways
Cell cycle38
8.6TGFB3, MYC, PCNA, CDH1
288.6IGF2, VEGFA, BMP6, FGF2
298.6TGFB3, MYC, PCNA, CTNNB1
30
Show member pathways
8.5IGF2, TGFB3, BMP6, ZAP70, FGF2
31
Show member pathways
8.5IGF2, TGFB3, BMP6, KIT, FGF2
32
Show member pathways
Signaling Pathways in Glioblastoma38
8.4FGF2, CTNNB1, CDH1, MYC, VEGFA
338.4TGFB3, MYC, BMP6, CDH1, CTNNB1
348.4VEGFA, ESR1, MYC, CDH1, CTNNB1
35
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
36
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
37
Show member pathways
8.2IGF2, TGFB3, BMP6, KIT, ZAP70, FGF2
38
Show member pathways
8.2VEGFA, KIT, ZAP70, CDH1, CTNNB1, FGF2
39
Show member pathways
8.0IGF2, TGFB3, BMP6, KIT, CTNNB1, FGF2
407.9VEGFA, TGFB3, MYC, KIT, CDH1, CTNNB1
41
Show member pathways
7.9IGF2, TGFB3, MYC, BMP6, KIT, ZAP70
427.9IGF2, VEGFA, ESR1, MYC, CTNNB1, FGF2
43
Show member pathways
Signal transduction PTEN pathway60
7.8TGFB3, MYC, PCNA, KIT, CDH1, CTNNB1
44
Show member pathways
7.7IGF2, TGFB3, MYC, BMP6, KIT, CDH1
457.7VEGFA, ESR1, MYC, PCNA, CTNNB1, FGF2
46
Show member pathways
7.5IGF2, TGFB3, BMP6, KIT, CDH1, CTNNB1
47
Show member pathways
7.5IGF2, TGFB3, ESR1, MYC, BMP6, KIT
48
Show member pathways
7.3IGF2, VEGFA, PGR, ESR1, MYC, KIT
49
Show member pathways
7.1IGF2, TGFB3, ESR1, BMP6, KIT, CDH1
50
Show member pathways
6.5FGF2, IGF2, TGFB3, ESR1, MYC, BMP6

Compounds for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Compounds related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 198)
idCompoundScoreTop Affiliating Genes
1everolimus45 51 1311.3VEGFA, KIT, MYC, ESR1
2triphenylethylene459.2PGR, ESR1, BMP6
3trastuzumab45 51 1310.9VEGFA, PGR, ESR1, KIT, CTNNB1
4danazol45 26 1310.7PGR, PCNA, CDH1, ESR1
5docetaxel45 51 61 1311.6PGR, ESR1, CDH1, VEGFA, KIT, MYC
6methylcellulose458.6CDH1, KIT, IGF2, CTNNB1, FGF2
7geldanamycin45 51 61 1311.5CTNNB1, CDH1, ESR1, PGR, KIT, VEGFA
8hyaluronic acid45 269.5VEGFA, BMP6, FGF2, MYC, ENG, CDH1
9progestin458.5IGF2, VEGFA, TGFB3, CDH1, ESR1, PGR
10dfmo45 30 6110.2MYC, CDH1, CTNNB1, IGF2
11celecoxib45 61 30 51 26 1313.2VEGFA, PCNA, CDH1, CTNNB1, FGF2
12matrigel458.1VEGFA, FGF2, ACTC1, CTNNB1, CDH1, ENG
13retinoid458.1CDH1, MYC, ESR1, BMP6, CTNNB1, PGR
14ribonucleic acid458.1ACTC1, IGF2, BMP6, H19, KIT, MYC
15pd 98,059458.1CDH1, CTNNB1, BMP6, MYC, KIT, ZAP70
164-hydroxytamoxifen458.0TGFB3, IGF2, ESR1, MYC, BMP6, CTNNB1
17tgf beta1458.0FGF2, CTNNB1, CDH1, BMP6, TGFB3, IGF2
18steroid458.0ACTC1, KIT, H19, IGF2, TGFB3, PGR
19methotrexate51 45 139.9CDH1, PGR, ESR1, PCNA, KIT, BMP6
20gefitinib45 51 139.9ESR1, KIT, CDH1, CTNNB1, IGF2, FGF2
21mg 13245 618.9CDH1, VEGFA, ESR1, MYC, PCNA, CTNNB1
22suramin45 30 139.8VEGFA, BMP6, FGF2, IGF2, PCNA
23imatinib45 51 139.7IGF2, VEGFA, CTNNB1, ZAP70, KIT, BMP6
24rapamycin457.6BMP6, CDH1, MYC, CTNNB1, IGF2, VEGFA
25dihydrotestosterone45 30 26 1310.5BMP6, PGR, ESR1, CDH1, CTNNB1, FGF2
26doxorubicin45 51 139.4ENG, CDH1, PGR, VEGFA, KIT, ESR1
27indomethacin45 30 61 1310.4PCNA, IGF2, CDH1, MYC, BMP6, PGR
28phosphatidylinositol457.3FGF2, IGF2, MYC, BMP6, KIT, ZAP70
29agar457.3FGF2, CTNNB1, CDH1, ENG, H19, BMP6
30ly294002457.3IGF2, FGF2, MYC, CTNNB1, CDH1, BMP6
31glutamine457.2CTNNB1, KIT, BMP6, PGR, IGF2, CDH1
32cycloheximide457.2BMP6, IGF2, VEGFA, PGR, ESR1, MYC
33heparin45 30 26 1310.1ZAP70, IGF2, BMP6, FGF2, PCNA, VEGFA
34genistein45 30 61 3 26 1312.1FGF2, CTNNB1, CDH1, ZAP70, PCNA, VEGFA
35testosterone45 61 26 1310.0PCNA, ACTC1, KIT, CTNNB1, PGR, ESR1
36oligonucleotide457.0MYC, KIT, BMP6, PCNA, ZAP70, ENG
375fluorouracil456.9IGF2, VEGFA, TGFB3, PGR, ESR1, PCNA
38cisplatin45 51 61 139.8VEGFA, ESR1, MYC, BMP6, CDH1, CTNNB1
395-aza-2deoxycytidine456.7PGR, ESR1, MYC, BMP6, H19, PCNA
40thymidine45 267.7IGF2, TGFB3, MYC, BMP6, H19, PCNA
41alanine456.7FGF2, CTNNB1, CDH1, BMP6, MYC, PCNA
42tamoxifen45 51 30 139.5ESR1, MYC, VEGFA, IGF2, BMP6, PGR
43progesterone45 30 61 26 1310.3IGF2, CTNNB1, CDH1, ENG, KIT, PCNA
44tyrosine456.2CDH1, ENG, IGF2, VEGFA, TGFB3, FGF2
45paclitaxel45 51 137.9VEGFA, PGR, ESR1, MYC, BMP6, PCNA
46dexamethasone45 51 30 138.6FGF2, CTNNB1, CDH1, ENG, ZAP70, PCNA
47retinoic acid45 266.6CDH1, H19, BMP6, ACTC1, MYC, KIT
48paraffin455.5PGR, TGFB3, VEGFA, IGF2, ESR1, MYC
49vegf455.2PCNA, BMP6, ACTC1, MYC, ESR1, PGR
50estrogen455.0ENG, FGF2, IGF2, KIT, PCNA, BMP6

GO Terms for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Cellular components related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:00163429.4CTNNB1, CDH1
2cytoplasmic side of plasma membraneGO:00098989.3KIT, CDH1, CTNNB1
3platelet alpha granule lumenGO:00310939.3TGFB3, VEGFA, IGF2
4cell surfaceGO:00099869.1CDH1, ENG, TGFB3, VEGFA
5nucleoplasmGO:00056547.9PGR, ESR1, MYC, BMI1, PCNA, CTNNB1
6extracellular spaceGO:00056157.8FGF2, ENG, KIT, BMP6, ACTC1, TGFB3
7cytoplasmGO:00057376.5VEGFA, ACTC1, BMI1, BMP6, PCNA, ZAP70

Biological processes related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 42)
idNameGO IDScoreTop Affiliating Genes
1detection of hypoxiaGO:007048310.4ENG, TGFB3
2central nervous system vasculogenesisGO:002200910.1CTNNB1, ENG
3cell migration involved in sprouting angiogenesisGO:000204210.0FGF2, VEGFA
4positive regulation of collagen biosynthetic processGO:003296710.0TGFB3, ENG
5positive regulation of blood vessel endothelial cell migrationGO:004353610.0FGF2, VEGFA
6mammary gland alveolus developmentGO:006074910.0ESR1, VEGFA
7activation of MAPK activityGO:000018710.0TGFB3, KIT, FGF2
8transforming growth factor beta receptor signaling pathwayGO:000717910.0TGFB3, MYC, ENG
9positive regulation of fibroblast proliferationGO:00481469.9ESR1, MYC, BMI1
10artery morphogenesisGO:00488449.9ENG, VEGFA
11positive regulation of phospholipase C activityGO:00108639.9ESR1, KIT, FGF2
12positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.9TGFB3, BMP6, ENG
13regulation of protein localization to cell surfaceGO:020000089.9CDH1, CTNNB1
14cellular response to indole-3-methanolGO:00716819.9CDH1, CTNNB1
15digestive tract developmentGO:00485659.9KIT, TGFB3
16positive regulation of gene expressionGO:00106289.8VEGFA, KIT, ENG
17response to hypoxiaGO:00016669.8VEGFA, TGFB3, ENG
18positive regulation of neuroblast proliferationGO:00020529.8CTNNB1, VEGFA
19positive regulation of endothelial cell differentiationGO:00456039.8CTNNB1, BMP6
20positive regulation of protein secretionGO:00507149.7BMP6, TGFB3
21patterning of blood vesselsGO:00015699.7VEGFA, ENG, CTNNB1
22regulation of angiogenesisGO:00457659.7CTNNB1, FGF2
23branching involved in ureteric bud morphogenesisGO:00016589.7FGF2, CTNNB1, MYC
24male genitalia developmentGO:00305399.6CTNNB1, BMP6
25positive regulation of mesenchymal cell proliferationGO:00020539.6VEGFA, MYC, CTNNB1
26positive regulation of epithelial cell proliferationGO:00506799.6BMP6, MYC, VEGFA
27positive regulation of phosphatidylinositol 3-kinase activityGO:00435529.6FGF2, KIT
28positive regulation of endothelial cell proliferationGO:00019389.6FGF2, BMP6, VEGFA
29platelet degranulationGO:00025769.6TGFB3, VEGFA, IGF2
30positive regulation of protein phosphorylationGO:00019349.5ENG, VEGFA, IGF2
31positive regulation of osteoblast differentiationGO:00456699.5BMP6, CTNNB1, FGF2
32positive regulation of MAPK cascadeGO:00434109.4IGF2, KIT, CTNNB1
33positive regulation of cell divisionGO:00517819.3FGF2, TGFB3, VEGFA, IGF2
34phosphatidylinositol-mediated signalingGO:00480159.3FGF2, KIT, PCNA
35response to estradiolGO:00323559.3IGF2, ESR1, CTNNB1
36response to cadmium ionGO:00466869.3CTNNB1, PCNA
37negative regulation of transcription from RNA polymerase II promoterGO:00001229.1CTNNB1, ENG, BMI1, MYC, VEGFA
38positive regulation of transcription, DNA-templatedGO:00458939.0TGFB3, MYC, CDH1, CTNNB1, FGF2
39cellular response to mechanical stimulusGO:00712609.0IGF2, BMP6, ENG, CTNNB1
40positive regulation of cell proliferationGO:00082848.9FGF2, KIT, MYC, VEGFA, IGF2
41response to drugGO:00424938.7CTNNB1, CDH1, ACTC1, MYC, IGF2
42positive regulation of transcription from RNA polymerase II promoterGO:00459447.3FGF2, IGF2, VEGFA, TGFB3, ESR1, MYC

Molecular functions related to Juvenile Nasopharyngeal Angiofibroma according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1type I transforming growth factor beta receptor bindingGO:003471310.2TGFB3, ENG
2type II transforming growth factor beta receptor bindingGO:000511410.1TGFB3, ENG
3transforming growth factor beta bindingGO:005043110.1ENG, TGFB3
4steroid bindingGO:00054969.8ESR1, PGR
5chemoattractant activityGO:00420569.6FGF2, VEGFA
6cytokine activityGO:00051258.9FGF2, BMP6, VEGFA
7identical protein bindingGO:00428028.6VEGFA, TGFB3, ESR1, PCNA
8growth factor activityGO:00080838.5IGF2, VEGFA, TGFB3, BMP6, FGF2
9protein bindingGO:00055155.3FGF2, IGF2, VEGFA, TGFB3, PGR, ESR1

Products for genes affiliated with Juvenile Nasopharyngeal Angiofibroma

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Sources for Juvenile Nasopharyngeal Angiofibroma

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet