KD
MCID: KWS002
MIFTS: 76

Kawasaki Disease (KD) malady

Rare diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases, Immune diseases categories
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Summaries for Kawasaki Disease

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MedlinePlus:33 Kawasaki disease is a rare childhood disease. it makes the walls of the blood vessels in the body become inflamed. it can affect any type of blood vessel, including the arteries, veins, and capillaries. no one knows what causes kawasaki disease. symptoms include high fever that lasts longer than 5 days swollen lymph nodes in the neck a rash on the mid-section and genital area red, dry, cracked lips and a red, swollen tongue red, swollen palms of the hands and soles of the feet redness of the eyes kawasaki disease can't be passed from one child to another. there is no single test. to diagnose it, doctors look at the signs and symptoms. they may also use an echocardiogram or other tests. it is mainly treated with medicines. rarely, medical procedures and surgery also may be used for children whose coronary arteries are affected. kawasaki disease can't be prevented. however, most children who develop the disease fully recover - usually within weeks of getting signs and symptoms. further problems are rare. nih: national heart, lung, and blood institute

MalaCards based summary: Kawasaki Disease, also known as mucocutaneous lymph node syndrome, is related to aneurysm and rheumatic fever, and has symptoms including chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis, oral mucosa disease/cheilitis and glossitis. An important gene associated with Kawasaki Disease is ITPKC (inositol-trisphosphate 3-kinase C), and among its related pathways are A-beta Uptake and Degradation and Development Leptin signaling via JAK STAT and MAPK cascades. The compounds neopterin and (4-aminophenyl)mercuric acetate have been mentioned in the context of this disorder. Affiliated tissues include body, lymph node and tongue, and related mouse phenotypes are tumorigenesis and muscle.

Disease Ontology:8 A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and characterized by inflammation of medium-sized blood vessels located in body, has symptom fever, has symptom congestion of ocular conjunctivae, has symptom reddening of lips, has symptom reddening of oral cavity, has symptom protuberance of tongue papillae and has symptom edema of extremities.

Genetics Home Reference:21 Kawasaki disease is a sudden and time-limited (acute) illness that affects infants and young children. Affected children develop a prolonged fever lasting several days, a skin rash, and swollen lymph nodes in the neck (cervical lymphadenopathy). They also develop redness in the whites of the eyes (conjunctivitis) and redness (erythema) of the lips, lining of the mouth (oral mucosa), tongue, palms of the hands, and soles of the feet.

NIH Rare Diseases:42 Kawasaki syndrome is a condition that involves inflammation of the blood vessels. it is typically diagnosed in young children, but older children and adults can also develop this condition.  kawasaki syndrome is usually accompanied by a fever that lasts at least 5 days. other classic symptoms may include red eyes, lips, and mouth; rash; swollen and red hands and feet; and swollen lymph nodes. kawasaki syndrome occurs most often in people of asian and pacific island descent. last updated: 1/12/2009

Wikipedia:65 For other uses see Kawasaki more...

Description from OMIM:46 611775

Aliases & Classifications for Kawasaki Disease

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Kawasaki Disease, Aliases & Descriptions:

Name: Kawasaki Disease 8 42 21 46 10 44 48 33
Mucocutaneous Lymph Node Syndrome 8 42 21 48 62
Acute Febrile Mucocutaneous Lymph Node Syndrome 8 21 62
Kawasaki Syndrome 42 21
Kd 21 62
 
Kawasaki Disease, Susceptibility to 9
Kawasaki's Disease 8
Acute Febrile Mcls 8
Mlns 8


Classifications:



Characteristics (Orphanet epidemiological data):

48
kawasaki disease:
Inheritance: Sporadic; Age of onset: Neonatal/infancy


External Ids:

Disease Ontology8 DOID:13378
OMIM46 611775
NCIt39 C34825
ICD9CM27 446.1
MeSH34 D009080
ICD10 via Orphanet26 M30.3
ICD1025 M30.3

Related Diseases for Kawasaki Disease

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Diseases related to Kawasaki Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 314)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm31.6ELANE, MMP3, MMP9, SELL
2rheumatic fever31.2MBL2, CRP
3arthritis30.7TIMP1, SELL, MMP3
4meningitis30.5MMP9, CRP, MBL2
5aspergillosis30.5ELANE, MBL2
6neutropenia30.4GPT, ELANE, MBL2
7myocardial infarction30.3NPPB, CRP, ADM, SELL
8acute myocardial infarction30.2MMP9, ADM, CRP, NPPB
921-hydroxylase deficiency30.2TIMP1, GPT
10hepatitis30.1GPT, HSPD1, SELL
11hepatitis b30.0MBL2, MMP3, MYD88, GPT
12juvenile rheumatoid arthritis30.0CRP, HSPD1
13obesity30.0GPT, SELL, MMP3, CCL2, CRP
14pulmonary hypertension30.0ADM, ELANE, NPPB
15vasculitis29.9HSPD1, SELL, ELANE, CCL2, ITPKC, CRP
16atopic dermatitis29.8FCER2, TIMP1, SELL, CCL2
17tuberculosis29.8HSPD1, SELL, MYD88, CRP, MBL2
18systemic lupus erythematosus29.7HSPD1, FCER2, MMP3, CCL2, CRP, MBL2
19vascular disease29.6HSPD1, MMP9, ELANE, CCL2, CRP
20hypertension29.6MMP9, ADM, CCL2, CRP, NPPB
21pneumonia29.5SELL, MYD88, ADM, ELANE, CCL2, CRP
22diabetes mellitus28.9GPT, HSPD1, SELL, MMP9, MMP3, CCL2
23atherosclerosis28.7HSPD1, TIMP1, SELL, MYD88, MMP9, MMP3
24sepsis28.5NPPB, MBL2, CRP, CCL2, HSPD1, SELL
25asthma28.4FCER2, TIMP1, SELL, MMP9, MMP3, ADM
26rheumatoid arthritis28.4HSPD1, FCER2, TIMP1, SELL, MMP9, MMP3
27coronary artery aneurysm10.9
28coronary aneurysm10.8
29endotheliitis10.7
30cholecystitis10.5GPT
31cryptococcosis10.5SELL
32scrub typhus10.5GPT
33aortic aneurysm10.5CRP
34bronchitis10.5CRP
35arthus reaction10.4SELL, ELANE
36abdominal aortic aneurysm10.4MMP9
37endocarditis10.4
38bronchiolitis10.4FCER2
39pyuria10.4
40cervicitis10.4
41trachoma10.4HSPD1
42bronchiectasis10.4MBL2, ELANE
43bacteremia10.4CRP, MBL2
44pulmonary emphysema10.4MMP9, ELANE
45common variable immunodeficiency10.3SELL, MBL2
46malaria10.3HSPD1, FCER2
47primary sclerosing cholangitis10.3GPT, ELANE
48chorioamnionitis10.3ELANE, CRP
49hemophagocytic lymphohistiocytosis10.3
50carotid stenosis10.3MMP9, CRP

Graphical network of the top 20 diseases related to Kawasaki Disease:



Diseases related to kawasaki disease

Symptoms for Kawasaki Disease

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Clinical features from OMIM:

611775

Symptoms:

48 (show all 40)
  • chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis
  • oral mucosa disease/cheilitis
  • glossitis
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • pharyngitis
  • vascularitis/vasculitides/arteritis
  • lymphadenopathy/polyadenopathies
  • proteinuria
  • dry/squaly skin/exfoliation
  • enanthema/aphtosa/aphta/leukoplakia
  • cutaneous edema
  • abnormal nails colour/leukonychia/melanonychia
  • acute abdominal pain/colic
  • acute diarrhea
  • cardiac valvulopathy
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • acute ischemic syndrome
  • arthritis/synovitis/synovial proliferation
  • hyperleukocytosis/leukocytosis
  • fever/chilling
  • asthenia/fatigue/weakness
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • ptosis
  • dermal/subcutaneous infiltration/induration
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • biliary/gallbladder stones/lithiasis/cholecystitis
  • hepatitis/icterus/cholestasis
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • myocardium anomalies/myocarditis
  • aortic root dilatation/dilation/aneurysm
  • cardiac rhythm disorder/arrhythmia
  • angor pectoris/myocardial infarction
  • heart/cardiac failure
  • aseptic leukocyturia
  • cranial nerves palsy
  • facial pain/cephalalgia/migraine
  • meningitis/meningeal syndrome
  • humour troubles/anxiety/depression/apathy/euphoria/irritability
  • articular/joint pain/arthralgia

HPO human phenotypes related to Kawasaki Disease:

(show all 33)
id Description Frequency HPO Source Accession
1 proteinuria hallmark (90%) HP:0000093
2 glossitis hallmark (90%) HP:0000206
3 skin rash hallmark (90%) HP:0000988
4 vasculitis hallmark (90%) HP:0002633
5 lymphadenopathy hallmark (90%) HP:0002716
6 inflammatory abnormality of the eye hallmark (90%) HP:0100533
7 recurrent pharyngitis hallmark (90%) HP:0100776
8 cheilitis hallmark (90%) HP:0100825
9 dry skin typical (50%) HP:0000958
10 edema typical (50%) HP:0000969
11 arthritis typical (50%) HP:0001369
12 abnormality of the heart valves typical (50%) HP:0001654
13 abnormality of the pericardium typical (50%) HP:0001697
14 leukocytosis typical (50%) HP:0001974
15 diarrhea typical (50%) HP:0002014
16 abdominal pain typical (50%) HP:0002027
17 abnormality of temperature regulation typical (50%) HP:0004370
18 abnormality of nail color typical (50%) HP:0100643
19 ptosis occasional (7.5%) HP:0000508
20 behavioral abnormality occasional (7.5%) HP:0000708
21 biliary tract abnormality occasional (7.5%) HP:0001080
22 meningitis occasional (7.5%) HP:0001287
23 congestive heart failure occasional (7.5%) HP:0001635
24 abnormality of the myocardium occasional (7.5%) HP:0001637
25 coronary artery disease occasional (7.5%) HP:0001677
26 nausea and vomiting occasional (7.5%) HP:0002017
27 migraine occasional (7.5%) HP:0002076
28 restrictive lung disease occasional (7.5%) HP:0002091
29 arthralgia occasional (7.5%) HP:0002829
30 dilatation of the ascending aorta occasional (7.5%) HP:0005111
31 cranial nerve paralysis occasional (7.5%) HP:0006824
32 arrhythmia occasional (7.5%) HP:0011675
33 aseptic leukocyturia occasional (7.5%) HP:0100586

Drugs & Therapeutics for Kawasaki Disease

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Drug clinical trials:

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Genetic Tests for Kawasaki Disease

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Anatomical Context for Kawasaki Disease

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MalaCards organs/tissues related to Kawasaki Disease:

32
Lymph node, Tongue, Eye, Heart, Skin, Endothelial, Testes, Lung, Brain, Monocytes, T cells, Bone, Neutrophil, Whole blood, Kidney, Liver, Tonsil, Myeloid, B cells

FMA organs/tissues related to Kawasaki Disease:

14
Body

Animal Models for Kawasaki Disease or affiliated genes

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MGI Mouse Phenotypes related to Kawasaki Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.3TIMP1, SELL, MYD88, MMP9, ELANE, CCL2
2MP:00053697.9NPPB, CCL2, ADM, MMP9, HSPD1
3MP:00053887.8TIMP1, SELL, MYD88, MMP9, ADM
4MP:00053847.4HSPD1, FCER2, SELL, MYD88, MMP9, ADM
5MP:00053897.4HSPD1, TIMP1, MYD88, MMP9, ADM, CCL2
6MP:00053857.0TIMP1, SELL, MYD88, MMP9, ADM, CCL2
7MP:00107686.7HSPD1, FCER2, TIMP1, MYD88, MMP9, ADM
8MP:00053976.3MYD88, SELL, TIMP1, FCER2, MMP9, MMP3
9MP:00053766.1MYD88, SELL, TIMP1, FCER2, MMP9, MMP3
10MP:00053875.9MBL2, FCER2, TIMP1, SELL, MYD88, MMP9

Publications for Kawasaki Disease

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Articles related to Kawasaki Disease:

(show top 50)    (show all 910)
idTitleAuthorsYear
1
Peribronchovascular haze: a frequently observed finding on chest X-rays in the acute phase of Kawasaki disease. (24293071)
2014
2
JNK is critical for the development of Candida albicans-induced vascular lesions in a mouse model of Kawasaki Disease. (25242023)
2014
3
The Late Sequalae of Coronary Artery in A Grown Up Kawasaki Disease Patient. (23629576)
2013
4
FcI^R gene copy number in Kawasaki disease and intravenous immunoglobulin treatment response. (23778324)
2013
5
Bilateral giant coronary aneurysms in Kawasaki disease: how difficult can it be? (24218442)
2013
6
Carotid intima-media thickness in children with Kawasaki disease. (23925993)
2013
7
Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in a Pediatric Patient with Giant Coronary Aneurysm Due to Kawasaki Disease. (23601472)
2013
8
Incomplete Kawasaki disease. (23481152)
2013
9
Comparison of patients with Kawasaki disease with retropharyngeal edema and patients with retropharyngeal abscess. (24146166)
2013
10
Histopathological study of lymph node lesions in the acute phase of Kawasaki disease. (23020240)
2013
11
Incomplete clinical manifestation as a risk factor for coronary artery abnormalities in Kawasaki disease: a meta-analysis. (23229186)
2013
12
National Japanese survey of thrombolytic therapy selection for coronary aneurysm: Intracoronary thrombolysis or intravenous coronary thrombolysis in patients with Kawasaki disease. (23919576)
2013
13
Genetics of Kawasaki disease: what we know and don't know. (22789975)
2012
14
Efficacy of plasma exchange therapy for Kawasaki disease by cytokine profiling. (22607573)
2012
15
Marked variations in serial coronary artery diameter measures in Kawasaki disease: a new indicator of coronary involvement. (22824173)
2012
16
Persistent coronary arterial inflammation in a patient long after the onset of Kawasaki disease. (22075420)
2012
17
Is Kawasaki disease a new disease?--a pathological perspective. (22343197)
2012
18
Pachyman treatment improves CD4+CD25+ Treg counts and serum interleukin 4 and interferon I^ levels in a mouse model of Kawasaki disease. (22367425)
2012
19
Regulation of oxidative stress in patients with Kawasaki disease. (22012196)
2012
20
Initial characteristics of Kawasaki disease with cerebrospinal fluid pleocytosis in febrile infants. (22964439)
2012
21
Circulating levels of the adipocytokines vaspin and omentin in patients with Kawasaki disease. (21442174)
2012
22
Symptomatic myocarditis in Kawasaki disease. (21863318)
2012
23
Associated symptoms of kawasaki disease. (21860641)
2011
24
Kawasaki disease in ghana: case reports from Korle Bu teaching hospital. (21572825)
2011
25
The functions of endothelial progenitor cells were significantly improved after treatment with intravenous immunoglobulin and aspirin in children with Kawasaki disease. (21327631)
2011
26
Incomplete Kawasaki disease in a patient with chronic granulomatous disease. (20723110)
2010
27
Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children. (20628649)
2010
28
Serum resistin concentrations in children with Kawasaki disease. (20422438)
2010
29
Cytokine genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children. (21048327)
2010
30
Sensorineural hearing loss: an underdiagnosed complication of Kawasaki disease. (20859226)
2010
31
Common variants in CASP3 confer susceptibility to Kawasaki disease. (20423928)
2010
32
Promoter polymorphism (rs3755724, -55C/T) of tissue inhibitor of metalloproteinase 4 (TIMP4) as a risk factor for Kawasaki disease with coronary artery lesions in a Korean population. (19048177)
2009
33
Influence of interleukin 18 promoter polymorphisms in susceptibility to Kawasaki disease in Taiwan. (18484687)
2008
34
Inflammatory gene polymorphisms and susceptibility to kawasaki disease and its arterial sequelae. (18710885)
2008
35
Genetic variations of HLA-DRB1 and susceptibility to Kawasaki disease in Taiwanese children. (17207714)
2007
36
Elastolytic matrix metalloproteinases and coronary outcome in children with Kawasaki disease. (17426658)
2007
37
Persistent monocytosis after intravenous immunoglobulin therapy correlated with the development of coronary artery lesions in patients with Kawasaki disease. (17932598)
2007
38
Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease. (15889128)
2005
39
Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease. (15962231)
2005
40
Modulating effects of mannose binding lectin genotype on arterial stiffness in children after Kawasaki disease. (15295097)
2004
41
Polymorphisms of heme oxygenase-1 and bilirubin UDP-glucuronosyltransferase genes are not associated with Kawasaki disease susceptibility. (14521259)
2003
42
Increased frequency of alleles associated with elevated tumor necrosis factor-alpha levels in children with Kawasaki disease. (11328953)
2001
43
Elevated serum levels of macrophage colony-stimulating factor in patients with Kawasaki disease complicated by cardiac lesions. (11791654)
2001
44
Expression of IL-8 in Kawasaki disease. (11122263)
2000
45
Increased levels of circulating soluble CD14 in Kawasaki disease. (10632678)
2000
46
Polyclonal expansion of TCRBV2- and TCRBV6-bearing T cells in patients with Kawasaki disease. (10233729)
1999
47
Analysis of tumor necrosis factor-alpha production and polymorphisms of the tumor necrosis factor-alpha gene in individuals with a history of Kawasaki disease. (10453180)
1999
48
Morphologic and functional assessment of coronary aneurysm after Kawasaki disease by repeated dipyridamole-loading coronary angiography. (9708673)
1998
49
Presence in Kawasaki disease of antibodies to mycobacterial heat-shock protein HSP65 and autoantibodies to epitopes of human HSP65 cognate antigen. (7686092)
1993
50
Kawasaki disease presenting in an adult as inflammatory diarrhea. (3509115)
1987

Variations for Kawasaki Disease

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Expression for genes affiliated with Kawasaki Disease

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Expression patterns in normal tissues for genes affiliated with Kawasaki Disease

Search GEO for disease gene expression data for Kawasaki Disease.

Pathways for genes affiliated with Kawasaki Disease

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Compounds for genes affiliated with Kawasaki Disease

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Compounds related to Kawasaki Disease according to GeneCards/GeneDecks:

(show top 50)    (show all 218)
idCompoundScoreTop Affiliating Genes
1neopterin449.2ELANE, FCER2, GPT, MBL2, CRP
2(4-aminophenyl)mercuric acetate449.1TIMP1, MMP3, ELANE, MMP9
3pravastatin44 50 28 24 1113.1CRP, NPPB, GPT, CCL2
4leukotriene b444 61 2410.9FCER2, MMP9, ELANE, CCL2, SELL
5aprotinin44 119.9NPPB, ELANE, SELL, TIMP1, MMP9
6prednisolone44 28 1110.8NPPB, MMP3, SELL, GPT, MBL2, CRP
7valsartan44 61 28 1111.8TIMP1, CCL2, NPPB, CRP
8batimastat44 61 1110.8MMP9, FCER2, TIMP1, ELANE, MMP3
9alpha tocopherol448.6TIMP1, GPT, ELANE, CRP, MMP9
10doxycycline44 119.6TIMP1, HSPD1, MMP9, MMP3, ELANE
11simvastatin44 50 61 28 24 1113.5SELL, CRP, CCL2, MMP3, MMP9, GPT
12pioglitazone28 44 50 1111.3CRP, CCL2, TIMP1, NPPB, GPT, MMP9
13rosiglitazone28 44 50 24 1112.3CCL2, GPT, TIMP1, CRP, MMP9, NPPB
14cytochalasin d44 619.2MMP9, SELL, TIMP1, CCL2, MMP3
15fibrinogen448.2CRP, CCL2, HSPD1, GPT, MMP9, ELANE
16phorbol448.1MMP9, SELL, TIMP1, HSPD1, MMP3
17procollagen448.1TIMP1, NPPB, MMP9, MMP3, ADM
18vitamin d448.1MBL2, MMP3, ELANE, NPPB, TIMP1, GPT
19atorvastatin44 50 28 24 1112.1SELL, TIMP1, GPT, MMP9, CCL2, CRP
20genistein44 28 61 2 24 1112.9TIMP1, SELL, FCER2, MMP3, NPPB, CCL2
21prostacyclin447.8CCL2, NPPB, ELANE, TIMP1, ADM, CRP
22endotoxin447.8ADM, CRP, HSPD1, SELL, MYD88, CCL2
23aspartate447.7HSPD1, GPT, TIMP1, MMP9, CCL2, CRP
24n acetylcysteine447.7TIMP1, MMP3, HSPD1, GPT, CRP, MMP9
25rantes447.6MBL2, HSPD1, CCL2, SELL, MYD88, MMP9
26indomethacin44 28 61 1110.6HSPD1, TIMP1, SELL, MMP3, NPPB, ADM
27sb 20358044 618.6FCER2, TIMP1, SELL, MMP9, MMP3, CCL2
28superoxide44 248.6HSPD1, SELL, FCER2, ELANE, CCL2, ADM
29p002447.6NPPB, GPT, TIMP1, ADM, MMP9, CRP
30histamine44 28 249.5CCL2, NPPB, ADM, MMP3, SELL, TIMP1
31glutamine447.5GPT, MMP3, HSPD1, ELANE, FCER2, TIMP1
32norepinephrine44 24 119.3SELL, ELANE, CCL2, NPPB, TIMP1, CRP
33cyclosporin a44 28 619.2HSPD1, ADM, NPPB, GPT, TIMP1, MMP9
34serine447.2CCL2, MMP9, SELL, FCER2, TIMP1, MYD88
35oxygen44 248.1SELL, NPPB, MYD88, MMP3, CCL2, ADM
36pge2447.0TIMP1, ELANE, NPPB, SELL, FCER2, MMP9
37alanine446.9ADM, MMP3, MMP9, SELL, HSPD1, CRP
38cholesterol44 28 24 119.9TIMP1, MMP3, ADM, CCL2, CRP, GPT
39estrogen446.9TIMP1, MMP3, ADM, ELANE, MBL2, HSPD1
40cysteine446.9MBL2, ELANE, ADM, MMP3, MMP9, HSPD1
41retinoic acid44 247.9SELL, TIMP1, FCER2, HSPD1, ADM, ELANE
42lipid446.8CRP, MYD88, MBL2, NPPB, CCL2, ADM
43paraffin446.8MBL2, HSPD1, TIMP1, SELL, MMP9, MMP3
44creatinine446.7MBL2, NPPB, GPT, HSPD1, SELL, MMP9
45cycloheximide446.6CRP, CCL2, ADM, MMP3, MMP9, SELL
46tyrosine446.6HSPD1, FCER2, SELL, NPPB, MBL2, ADM
47glucose446.5GPT, CRP, HSPD1, MBL2, NPPB, CCL2
48dexamethasone44 50 28 119.5MMP3, TIMP1, HSPD1, MMP9, ADM, CCL2
49vegf446.3NPPB, ADM, CRP, CCL2, MBL2, MMP3
50lactate446.2SELL, GPT, FCER2, TIMP1, MMP9, MMP3

GO Terms for genes affiliated with Kawasaki Disease

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Cellular components related to Kawasaki Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056156.8MMP9, MMP3, ADM, CCL2, CRP, MBL2
2extracellular regionGO:0055766.1NPPB, TIMP1, MMP9, MMP3, ADM, ELANE

Biological processes related to Kawasaki Disease according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1opsonizationGO:00822810.0MBL2, CRP
2negative regulation of growth of symbiont in hostGO:04413010.0ELANE, MBL2
3positive regulation of nitric-oxide synthase biosynthetic processGO:0517709.8CCL2, FCER2
4defense response to Gram-positive bacteriumGO:0508309.8MYD88, CRP, MBL2
5leukocyte migrationGO:0509009.7ELANE, MMP9, SELL
6collagen catabolic processGO:0305749.6ELANE, MMP3, MMP9
7positive regulation of T cell activationGO:0508709.5HSPD1, CCL2
8proteolysisGO:0065089.4ELANE, MMP3, MMP9
9cell surface receptor signaling pathwayGO:0071669.0MYD88, CCL2, NPPB
10extracellular matrix disassemblyGO:0226179.0ELANE, MMP3, MMP9, TIMP1
11extracellular matrix organizationGO:0301988.9TIMP1, MMP9, MMP3, ELANE
12response to hypoxiaGO:0016668.6CRP, CCL2, ADM
13agingGO:0075688.4CRP, CCL2, ADM, TIMP1

Molecular functions related to Kawasaki Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.3ELANE, SELL, TIMP1
2heparin bindingGO:0082019.1SELL, ELANE, CCL2
3receptor bindingGO:0051028.4NPPB, MBL2, CCL2, ADM
4protein bindingGO:0055156.7TIMP1, SELL, MYD88, MMP9, ADM, ELANE

Products for genes affiliated with Kawasaki Disease

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Sources for Kawasaki Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet