MCID: KLD001
MIFTS: 34

Keloids malady

Genetic diseases (common) category
Download this MalaCard

Summaries for Keloids

About this section


Fully expand this MalaCard
Wikipedia:65 A keloid (/?ki?l??d/; also keloidal scar) is the formation of a type of scar which, depending on its... more...

MalaCards based summary: Keloids, also known as keloid, is related to hypertrophic scars and keloid formation, and has symptoms including An important gene associated with Keloids is MIR196A2 (microRNA 196a-2). Affiliated tissues include skin, endothelial and breast.

Aliases & Classifications for Keloids

About this section

Keloids, Aliases & Descriptions:

Name: Keloids 30 20
 
Keloid 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Keloids

About this section

Graphical network of the top 20 diseases related to Keloids:



Diseases related to keloids

Symptoms for Keloids

About this section

HPO human phenotypes related to Keloids:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 keloids HP:0010562

Drugs & Therapeutics for Keloids

About this section

Drug clinical trials:

Search ClinicalTrials for Keloids

Search NIH Clinical Center for Keloids

Genetic Tests for Keloids

About this section

Genetic tests related to Keloids:

id Genetic test Affiliating Genes
1 Keloids20

Anatomical Context for Keloids

About this section

MalaCards organs/tissues related to Keloids:

32
Skin, Endothelial, Breast, Eye, Lymph node, Smooth muscle, Kidney, T cells

Animal Models for Keloids or affiliated genes

About this section

Publications for Keloids

About this section

Articles related to Keloids:

(show top 50)    (show all 803)
idTitleAuthorsYear
1
Which is better option for the treatment of large neck keloids? Free tissue transfer versus skin grafting. (25086708)
2014
2
RUNX3 expression is associated with sensitivity to pheophorbide a-based photodynamic therapy in keloids. (24957188)
2014
3
Keloids in Rubinstein-Taybi syndrome: a clinical study. (25132000)
2014
4
Clinical and epidemiological analysis of keloids in Chinese patients. (25266787)
2014
5
Reply: Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids. (24076718)
2013
6
Keloid formation after trigger finger release: a case report. (23182345)
2013
7
Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids. (24182692)
2013
8
Pharmacological treatment for keloids. (23937443)
2013
9
Clinical features and outcomes of foot keloids treated using complete surgical excision and full thickness skin grafting followed by corticosteroid injections. (23856363)
2013
10
Prosthetic conformer as a pressure device in the prophylactic management of postsurgical auricular keloid formation: a clinical report. (23298199)
2013
11
New pressure device, "Magsil," as an adjuvant pressure therapy for ear keloids. (22801801)
2012
12
Nodular scleroderma presenting as multiple spontaneous keloidal scars. (22583729)
2012
13
A comparative clinical study on role of 5-flurouracil versus triamcinolone in the treatment of keloids. (23904725)
2012
14
Surgical excision and immediate postoperative radiotherapy versus cryotherapy and intralesional steroids in the management of keloids: a prospective clinical trial. (20639666)
2010
15
Earlobe keloids: emerging cosmetic complication of ear-piercing. (21243860)
2010
16
Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option. (20872224)
2010
17
Postoperative strontium-90 brachytherapy in the prevention of keloids: results and prognostic factors. (19101094)
2009
18
Unusual formation of keloids after each episode of recurrent herpes zoster in an HIV positive patient. (21938132)
2009
19
Keloidoscope: in search for the ideal treatment of keloids. (23139545)
2009
20
Matrix metalloproteinase-2 and -9 activities in human keloids, hypertrophic and atrophic scars: a pilot study. (19165813)
2009
21
Is radiation therapy for keloids acceptable? The risk of radiation-induced carcinogenesis. (19935303)
2009
22
A custom-made silicon mold for pressure therapy to ear keloids. (19322608)
2009
23
Isolation and characterization of multipotent human keloid-derived mesenchymal-like stem cells. (18710345)
2008
24
Correlation analysis between clinical phenotypes of keloids and polymorphism of p53 gene codon 72]. (19137883)
2008
25
Descriptive study of patients receiving excision and radiotherapy for keloids. (18249504)
2008
26
Keloids do not harbor EBV or HHV8. (17689878)
2008
27
Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts. (17550447)
2007
28
Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells. (17535221)
2007
29
Trisomy 9p associated with self-injured behaviour and multiple intractable keloids. (16922967)
2006
30
Pseudopterygium arising in a patient with multiple keloids. (16491728)
2006
31
Expressions of TGF-betaR I, Smad2, Smad3 and Smad7 in keloids]. (17144456)
2006
32
Gene expression patterns in isolated keloid fibroblasts. (16939575)
2006
33
Genetic susceptibility to keloid disease: mutation screening of the TGFbeta3 gene. (16043141)
2005
34
Activated caspase expression and apoptosis increase in keloids: cytochrome c release and caspase-9 activation during the apoptosis of keloid fibroblast lines. (16008726)
2005
35
Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects. (16365887)
2005
36
Pathological genomics of keloid fibroblastic cells]. (16248530)
2005
37
Retrospective analysis of treatment of unresectable keloids with primary radiation over 25 years. (15214654)
2004
38
Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts. (14708599)
2003
39
Phosphorylation of extracellular signal-regulated protein kinase in cultured keloid fibroblasts when stimulated by platelet-derived growth factor BB. (15328769)
2003
40
Insulin-like growth factor-I enhances transforming growth factor-beta-induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts. (12787120)
2003
41
Painless steroid injections for hypertrophic scars and keloids. (12706172)
2003
42
Fibrodysplasia ossificans progressiva and corneal keloid. (12352096)
2002
43
Zimmer splintage: a simple effective treatment for keloids following ear-piercing. (11513513)
2001
44
Aetiopathogenesis of keloids. (10862278)
1999
45
Altered posttranslational modifications of collagen in keloid. (9731191)
1998
46
The protruding scars: keloids and hypertrophic diagnosis and treatment with silicon-gel-sheeting. (7971533)
1994
47
Regulation of collagen gene expression in keloids and hypertrophic scars. (8412102)
1993
48
Treatment of keloids by 90Sr-90Y beta-rays. (1858015)
1991
49
Intralesional interferon gamma treatment for keloids and hypertrophic scars. (2119626)
1990
50
Follow-up on treatment of hypertrophic scars and keloids with triamcinolone. (5566476)
1971

Variations for Keloids

About this section

Expression for genes affiliated with Keloids

About this section
Expression patterns in normal tissues for genes affiliated with Keloids

Search GEO for disease gene expression data for Keloids.

Pathways for genes affiliated with Keloids

About this section

Compounds for genes affiliated with Keloids

About this section

GO Terms for genes affiliated with Keloids

About this section

Biological processes related to Keloids according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ovarian follicle developmentGO:0015419.6FOXL2, MMP19
2cell differentiationGO:0301549.5FOXL2, MMP19, TNFSF12

Products for genes affiliated with Keloids

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Keloids

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet