Categories: Genetic diseases, Rare diseases, Eye diseases
50OMIM, 11Disease Ontology, 13DISEASES, 25GTR, 12diseasecard, 48Novoseek, 37MeSH, 66UMLS, 46NIH Rare Diseases, 52Orphanet, 68UniProtKB/Swiss-Prot, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 35MedGen, 60SNOMED-CT, 62The Human Phenotype Ontology
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Aliases & Descriptions for Keratitis:
Orphanet epidemiological data:52
autosomal dominant keratitis:
Inheritance: Autosomal dominant; Age of onset: Childhood; Age of death: normal life expectancy
Inheritance: autosomal dominant inheritance
Global: Genetic diseases, Rare diseases
Anatomical: Eye diseases
ICD10: 29 28
Rare eye diseases
OMIM:50 Keratitis is a rare ocular disorder presenting with congenital and progressive features predominantly involving the... (148190) more...
MalaCards based summary: Keratitis, also known as keratitis, hereditary, is related to mycobacterium gordonae and herpes zoster, and has symptoms including visual disturbance, keratitis and opacification of the corneal stroma. An important gene associated with Keratitis is PAX6 (Paired Box 6), and among its related pathways are LDL Oxidation in Atherogenesis and Th17 Differentiation Pathway. The drugs loteprednol etabonate and loteprednol have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and lung, and related mouse phenotypes are integument and muscle.
Disease Ontology:11 A corneal disease that is characterized by inflammation of the cornea.
CDC:2 Acanthamoeba is a microscopic, free-living ameba, or amoeba* (single-celled living organism), that can cause rare, but severe infections of the eye, skin, and central nervous system. The ameba is found worldwide in the environment in water and soil. The ameba can be spread to the eyes through contact lens use, cuts, or skin wounds or by being inhaled into the lungs. Most people will be exposed to Acanthamoeba during their lifetime, but very few will become sick from this exposure. The three diseases caused by Acanthamoeba are:
UniProtKB/Swiss-Prot:68 Keratitis hereditary: An ocular disorder characterized by corneal opacification, recurrent stromal keratitis and vascularization.
Wikipedia:69 Keratitis is a condition in which the eye\'s cornea, the front part of the eye, becomes inflamed. The... more...
Drugs for Keratitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show top 50) (show all 117)
Interventional clinical trials:(show top 50) (show all 478)
Search NIH Clinical Center for Keratitis
Inferred drug relations via UMLS66/NDF-RT44:
MalaCards organs/tissues related to Keratitis:34
Eye, Skin, Lung, T cells, Testes, Endothelial, B cells
MGI Mouse Phenotypes related to Keratitis:39 (show all 13)
Articles related to Keratitis:(show top 50) (show all 2107)
Search GEO for disease gene expression data for Keratitis.
Pathways related to Keratitis according to GeneCards Suite gene sharing:(show top 50) (show all 61)
Cellular components related to Keratitis according to GeneCards Suite gene sharing:
Biological processes related to Keratitis according to GeneCards Suite gene sharing:(show top 50) (show all 69)
Molecular functions related to Keratitis according to GeneCards Suite gene sharing:
29ICD10 via Orphanet
38MESH via Orphanet
51OMIM via Orphanet
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
67UMLS via Orphanet