MCID: KRT005
MIFTS: 45

Keratoacanthoma malady

Categories: Genetic diseases, Cancer diseases, Eye diseases, Skin diseases, Rare diseases

Aliases & Classifications for Keratoacanthoma

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Aliases & Descriptions for Keratoacanthoma:

Name: Keratoacanthoma 11 49 38 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:3149
MeSH38 D007636
NCIt44 C3146

Summaries for Keratoacanthoma

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Wikipedia:70 Keratoacanthoma (KA) is a common low-grade (unlikely to metastasize or invade) skin tumour that is... more...

MalaCards based summary: Keratoacanthoma is related to clear cell acanthoma and generalized eruptive keratoacanthoma, and has symptoms including exanthema, pruritus and skin manifestations. An important gene associated with Keratoacanthoma is MSH2 (MutS Homolog 2), and among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and GADD45 Pathway. Affiliated tissues include skin, thyroid and lung, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Keratoacanthoma

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Diseases in the Keratoacanthoma family:

Familial Keratoacanthoma

Diseases related to Keratoacanthoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1clear cell acanthoma29.5MLH1, TP53
2generalized eruptive keratoacanthoma12.0
3familial keratoacanthoma12.0
4vulvar keratoacanthoma-like carcinoma11.8
5multiple self-healing squamous epithelioma, susceptiblity to11.4
6muir-torre syndrome11.4
7peptic ulcer disease10.6MKI67, TP53
8split hand split foot malformation autosomal recessive10.6MKI67, TP53
9pasli disease10.6MSH2, TP53
10oral pharyngeal disorders10.6MKI67, TP53
11stampe sorensen syndrome10.5MKI67, TP53
12l-cell glucagon-like peptide producing tumor10.5MSH2, TP53
13liver lymphoma10.5KRT17, TP53
14epidermolytic acanthoma10.5KRT10, KRT17
15emerinopathy10.5MKI67, TP53
16cardiac granular cell neoplasm10.5GZMB, TP53
17conversion disorder10.5MSH2, TP53
18vulva basal cell carcinoma10.4KRT17, TP53
19metatypical basal cell carcinoma10.4KRT10, KRT17
20hemoglobin d disease10.4KRT10, KRT17
21lacrimal passage granuloma10.4GZMB, KRT10
22large intestine adenocarcinoma10.4MLH1, MSH2
23lung acinar adenocarcinoma10.4CDKN1A, TP53
24ureter inverted papilloma10.4CDKN1A, TP53
25mesenchymoma10.4KRT10, TP53
26mixed endometrial stromal and smooth muscle tumor10.4CDKN1A, TP53
27sialolithiasis10.4GZMB, MKI67, TP53
28neuropathy, distal hereditary motor, type viib10.4MLH1, MSH2
29angioimmunoblastic lymphadenopathy with dysproteinemia10.4MLH1, MSH2
30spleen angiosarcoma10.4MLH1, MSH2
31ampulla of vater squamous cell carcinoma10.4MLH1, TP53
32pityriasis rosea10.4MLH1, MSH2
33novak syndrome10.4MKI67, TP53
34anal squamous cell carcinoma10.3KRT17, TP53
35cervical adenomyoma10.3MLH1, MSH2
36x-linked congenital generalized hypertrichosis10.3KRT17, MKI67, TP53
37colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas10.3KRT10, KRT17
38geniculate herpes zoster10.3GZMB, KRT10, TP53
39hyperaldosteronism10.3MLH1, MSH2
40food allergy10.3MLH1, MSH2
41pyoderma10.3MLH1, TP53
42ichthyosis histrix, curth-macklin type10.3KRT10, KRT16
43otosclerosis10.2KRT16, KRT17
44antidepressant or antipsychotic toxicity or dose selection10.2MKI67, TP53
45sclerosteosis 110.2KRT16, KRT17
46clove syndrome, somatic10.2KRT10, RBP1, TP53
47pachyonychia congenita 210.2KRT16, KRT17
48colver steer godman syndrome10.2MLH1, MSH2, TP53
49nodular degeneration of cornea10.2MKI67, MLH1, TP53
50periapical granuloma10.2MLH1, MSH2, TP53

Graphical network of the top 20 diseases related to Keratoacanthoma:



Diseases related to keratoacanthoma

Symptoms for Keratoacanthoma

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UMLS symptoms related to Keratoacanthoma:


exanthema, pruritus, skin manifestations

Drugs & Therapeutics for Keratoacanthoma

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Drugs for Keratoacanthoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DabrafenibapprovedPhase 27944462760, 44516822
Synonyms:
BRAF inhibitor GSK2118436
Dabrafenib
 
GSK2118436
GSK2118436a
Tafinlar
dabrafenib
2
TrametinibapprovedPhase 2121871700-17-311707110
Synonyms:
GSK 1120212
GSK1120212
JTP 74057
JTP-74057
 
MEK Inhibitor GSK1120212
Mekinist
Trametinib Dimethyl Sulfoxide
Trametinibum
trametinib
3
nivolumabapprovedPhase 2326946414-94-4
Synonyms:
BMS-936558
 
MDX-1106
ONO-4538
nivolumab
4Protein Kinase InhibitorsPhase 23612
5ImmunoglobulinsPhase 26045
6Antibodies, MonoclonalPhase 23795
7AntibodiesPhase 26045
8
Sorafenibapproved, investigational692284461-73-0216239, 406563
Synonyms:
284461-73-0
4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide
4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate
4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
AB1004622
AC-1674
AC1L50CF
BAX
BAY 43-9006
BAY 43-9006 (free base)
BAY 43-9006 tosylate salt
BAY 439006
BAY 54-9085 (tosylate salt)
BAY-43-0006
BAY-43-9006
BAY-54-9085
BAY43-9006
BRD-K23984367-001-01-8
Bio-0100
CHEBI:47228
CHEBI:50924
CHEMBL1336
CID216239
 
D08524
DB00398
DB07438
EN002709
I06-0856
K00597a
Kinome_766
LS-186067
LS-187021
LS-187788
MolPort-003-850-270
N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea
NCGC00167488-01
NSC-724772
NSC747971
Nexavar
STK627350
Sorafenib
Sorafenib (INN)
Sorafenib [INN]
Sorafenib tosylate
Sorafenibum
UNII-9ZOQ3TZI87
ZINC01493878
nchembio.117-comp17
sorafenib
sorafenibum
9
Niacinapproved, investigational, nutraceutical90659-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Nicacid
Nicamin
Nicangin
 
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-╬▓-carboxylic acid
╬▓-pyridinecarboxylic acid
10
Nicotinamideapproved, Nutraceutical90298-92-0936
Synonyms:
.beta.-Pyridinecarboxamide
11032-50-1
123574-63-0
1yc5
3 Pyridinecarboxamide
3-Carbamoylpyridine
3-Pyridinecarboxamide
3-Pyridinecarboxylic acid amide
37321-14-5
47865U_SUPELCO
55600-01-6
63748-44-7
72340_FLUKA
72340_SIGMA
72347_FLUKA
78731-47-2
98-92-0
A186B02E-6C70-4E54-9739-79398D439AAA
AC-907/25014114
AC1L1ACZ
AC1Q4ZFV
AI3-02906
Acid amide
Amid kyseliny nikotinove
Amid kyseliny nikotinove [Czech]
Amide PP
Aminicotin
Amixicotyn
Amnicotin
Astra Brand of Niacinamide
Austrovit PP
B 3, Vitamin
B3, Vitamin
BB_NC-2290
Benicot
C00153
C6H6N2O
CCRIS 1901
CHEBI:17154
CHEMBL1140
CID936
CPD000058212
D00036
D009536
DB02701
DEA No. 1405
Delonin Amide
Delonin amide
Dipegyl
Dipigyl
EINECS 202-713-4
EINECS 234-265-0
Endobion
Enduramide
Factor pp
HMS2052M21
HMS2090B05
HMS2093H03
HSDB 1237
Hansamid
I02-1741
I02-2250
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Inovitan PP
Jenapharm Brand of Niacinamide
Jenapharm, Nicotinsaureamid
LS-2051
MLS000069714
Mediatric
Merck Brand of Niacinamide
MolMap_000061
MolPort-001-783-876
N0078
N0636_SIGMA
N2142_SIGMA
N3376_SIGMA
N5535_SIAL
NAM
NCGC00093354-03
NCGC00093354-04
NSC 13128
NSC13128
NSC27452
Nandervit-N
Niacevit
Niacinamide
Niacinamide (USP)
Niacinamide Astra Brand
Niacinamide Jenapharm Brand
Niacinamide Merck Brand
 
Niacinamide Pharmagenix Brand
Niacinamide [USAN]
Niacinamide, Nicotinic acid amide, Nicotinamide
Niacotinamide
Niamide
Niavit PP
Nicamide
Nicamina
Nicamindon
Nicasir
Nicobion
Nicofort
Nicogen
Nicomidol
Nicosan 2
Nicosylamide
Nicota
Nicotamide
Nicotilamide
Nicotililamido
Nicotinamid
Nicotinamida
Nicotinamida [INN-Spanish]
Nicotinamide
Nicotinamide (JP15/INN)
Nicotinamide (Niacinamide)
Nicotinamide, niacin, vitamin B3
Nicotinamide-carbonyl-14C
Nicotinamidum
Nicotinamidum [INN-Latin]
Nicotine acid amide
Nicotine amide
Nicotinic acid amide
Nicotinic amide
Nicotinsaeureamid
Nicotinsaureamid
Nicotinsaureamid Jenapharm
Nicotinsaureamid [German]
Nicotol
Nicotylamide
Nicotylamidum
Nicovel
Nicovit
Nicovitina
Nicovitol
Nicozymin
Nictoamide
Nikasan
Nikazan
Niko-tamin
Nikotinamid
Nikotinsaeureamid
Nikotinsaeureamid [German]
Niocinamide
Niozymin
PP-Faktor
Papulex
Pelmin
Pelmine
Pelonin amide
Pharmagenix Brand of Niacinamide
Propamine A
Pyridine-3-carboxylic acid amide
S1899_Selleck
SAM001246860
SGCUT00176
SMR000058212
Savacotyl
UNII-25X51I8RD4
Vi-Nicotyl
Vi-noctyl
Vitamin B
Vitamin B (VAN)
Vitamin B 3
Vitamin B3 amide
Vitamin H1
Vitamin PP
WLN: T6NJ CVZ
Witamina PP
ZINC00005878
b-Pyridinecarboxamide
beta-Pyridinecarboxamide
bmse000281
m-(Aminocarbonyl)pyridine
nchembio.154-comp4
nchembio.73-comp6
niacin - Vitamin B3
niacinamide
nicotinamide
pyridine-3-carboxamide
to_000073
vitamin PP
11
Folic Acidapproved, nutraceutical, vet_approved427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
12Trace Elements5802
13Vitamin B Complex4229
14Vitamins5095
15Micronutrients5802
16Nicotinic Acids906
17FolateNutraceutical4279
18Vitamin B3Nutraceutical906
19Vitamin B9Nutraceutical4279

Interventional clinical trials:

idNameStatusNCT IDPhase
1Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or TrametinibRecruitingNCT02314143Phase 2
2Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin CancersNot yet recruitingNCT02978625Phase 2
3A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic MelanomaWithdrawnNCT02068079Phase 1
4Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With SorafenibRecruitingNCT02185560

Search NIH Clinical Center for Keratoacanthoma


Cochrane evidence based reviews: keratoacanthoma

Genetic Tests for Keratoacanthoma

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Anatomical Context for Keratoacanthoma

About this section

MalaCards organs/tissues related to Keratoacanthoma:

35
Skin, Thyroid, Lung, Bone, Colon, Tongue, Cervix

Animal Models for Keratoacanthoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Keratoacanthoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4CDKN1A, KRT16, KRT17, MLH1, MSH2, TP53
2MP:00107717.7CDKN1A, KRT16, KRT17, MLH1, MSH2, TP53

Publications for Keratoacanthoma

About this section

Articles related to Keratoacanthoma:

(show top 50)    (show all 608)
idTitleAuthorsYear
1
Sonographic features of keratoacanthoma. May ultrasound be a useful tool to differentiate it from squamous cell carcinoma? (26681149)
2016
2
Keratoacanthoma of the conjunctiva in a young patient. (27463634)
2016
3
Unusual Ultrasound Appearance of Subungual Keratoacanthoma With Clinical and Histological Correlation. (26833061)
2016
4
Clues in DeRmoscopy: Dermoscopy of keratoacanthoma. (27528474)
2016
5
Case of generalized eruptive keratoacanthoma with probable SjAPgren's syndrome. (26119532)
2015
6
Recurrent facial keratoacanthoma in a patient with diabetes: a case report. (24758418)
2014
7
Keratoacanthoma accompanied by multiple lung squamous cell carcinomas developing in a renal transplant recipient. (25120468)
2014
8
Plasmacytoid dendritic cell involvement in the host response against keratoacanthoma. (24831321)
2014
9
Metastatic laryngeal carcinoma mimicking eruptive keratoacanthomas: report of keratoacanthoma-like cutaneous metastases in a radiation port. (25244165)
2014
10
Keratoacanthoma with secondary ossification. (23231325)
2014
11
Generalized eruptive keratoacanthoma: a diagnostic and therapeutic challenge. (25070745)
2014
12
Keratoacanthoma: an unusual nasal mass. (24376301)
2013
13
A case of granular cell tumor masquerading as a keratoacanthoma. (23627913)
2013
14
Spontaneous involution of keratoacanthoma, iconographic documentation and similarity with volcanoes of nature. (22570051)
2012
15
The nuclear factor kappa B p50 subunit and cortactin as markers to distinguish between keratoacanthoma and well-differentiated squamous cell carcinoma. (21883393)
2011
16
Cutaneous lupus erythematosus mimicking multiple keratoacanthomas. (19106056)
2009
17
Keratoacanthoma in a tattoo. (19903437)
2009
18
Eruptive squamous cell carcinomas, keratoacanthoma type, arising in a multicolor tattoo. (18095997)
2008
19
Benign fibrous histiocytoma of the eyelid mimicking keratoacanthoma. (17237703)
2007
20
A case of multiple keratoacanthomas associated with keratoacanthoma centrifugum marginatum. (16648927)
2006
21
HPV 6-positive giant keratoacanthoma in an immunocompetent patient. (16683389)
2006
22
Vulval Keratoacanthoma: a case report. (15863180)
2005
23
Multiple, keratoacanthoma-like nodules on a 47-year-old man: a rare presentation of cutaneous lupus erythematosus. (14636190)
2003
24
Conjunctival keratoacanthoma in an Asian. (12523897)
2003
25
Keratoacanthoma developing on a pigmented patch in incontinentia pigmenti. (10828638)
2000
26
Malignant changes in a giant orbital keratoacanthoma developing over 25 years. (10794263)
2000
27
Multiple keratoacanthoma with neonatal onset in a girl. (10627223)
1999
28
Keratoacanthoma centrifugum marginatum arising from a scar after skin injury. (10487013)
1999
29
Cutaneous sporotrichosis presenting as a keratoacanthoma. (9675531)
1998
30
Keratoacanthoma: is it a real entity? (9600429)
1998
31
Keratoacanthomas and lymphomatoid papulosis. (9700388)
1998
32
Generalized eruptive keratoacanthoma of Grzybowski: response to cyclophosphamide. (9146546)
1997
33
The paradoxical association of regression with a poor prognosis in melanoma contrasted with a good prognosis in keratoacanthoma. (8640780)
1996
34
Solitary intraoral keratoacanthoma: report of a case. (8765395)
1996
35
Keratoacanthoma versus squamous cell carcinoma. An immunohistochemical reappraisal of p53 protein and proliferating cell nuclear antigen expression in keratoacanthoma-like tumors. (8600793)
1995
36
Subungual keratoacanthoma masquerading as a chronic paronychia. (7702309)
1995
37
Keratoacanthoma in Japanese Hawaiians in Kauai, Hawaii. (8647663)
1995
38
Eruptive skin tags and keratoacanthomas in a patient with prolactinoma and colonic polyposis. (8075462)
1994
39
Nature of keratoacanthoma. (7943646)
1994
40
Keratoacanthoma versus squamous cell carcinoma of the lower lip. (2189352)
1990
41
Intralesional 5-fluorouracil for keratoacanthoma of the eyelid. (3154563)
1986
42
Treatment of keratoacanthoma with intralesional bleomycin. (6194810)
1983
43
Squamous-cell carcinoma vs. keratoacanthoma. (7096765)
1982
44
Keratoacanthoma arising in a linear epidermal nevus. (7082032)
1982
45
Hypocomplementemia in keratoacanthoma. (7247456)
1981
46
Successful treatment of keratoacanthoma with intralesional fluorouracil. (7364978)
1980
47
Immune response to human keratoacanthoma. (394758)
1979
48
Giant keratoacanthoma of the ear. (595076)
1977
49
Keratoacanthoma of the lower lip. Review of the literature and report of a case. (4531621)
1974
50
Keratoacanthoma of nailbed: a report of two cases. (4704160)
1973

Variations for Keratoacanthoma

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Expression for genes affiliated with Keratoacanthoma

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Search GEO for disease gene expression data for Keratoacanthoma.

Pathways for genes affiliated with Keratoacanthoma

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GO Terms for genes affiliated with Keratoacanthoma

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Cellular components related to Keratoacanthoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1condensed chromosomeGO:00007939.4MKI67, MLH1
2intermediate filamentGO:00058828.5FLG, KRT10, KRT16, KRT17

Biological processes related to Keratoacanthoma according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1somatic recombination of immunoglobulin genes involved in immune responseGO:000220410.5MLH1, MSH2
2determination of adult lifespanGO:000834010.4MSH2, TP53
3somatic hypermutation of immunoglobulin genesGO:001644610.4MLH1, MSH2
4somatic recombination of immunoglobulin gene segmentsGO:001644710.4MLH1, MSH2
5mismatch repairGO:000629810.4MLH1, MSH2
6isotype switchingGO:004519010.3MLH1, MSH2
7positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:190074010.3GZMB, TP53
8positive regulation of reactive oxygen species metabolic processGO:200037910.0CDKN1A, TP53
9cellular response to ionizing radiationGO:00714799.9CDKN1A, TP53
10replicative senescenceGO:00903999.9CDKN1A, TP53
11meiotic nuclear divisionGO:00071269.7MKI67, MLH1
12response to X-rayGO:00101659.7CDKN1A, MSH2, TP53
13intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:00427719.5CDKN1A, MSH2, TP53
14establishment of skin barrierGO:00614369.5FLG, KRT16
15reciprocal meiotic recombinationGO:00071319.5MLH1, MSH2
16intrinsic apoptotic signaling pathwayGO:00971939.4CDKN1A, TP53
17cell cycle arrestGO:00070509.3CDKN1A, MSH2, TP53
18keratinocyte differentiationGO:00302169.3FLG, KRT10, KRT16
19cellular response to DNA damage stimulusGO:00069748.8CDKN1A, MLH1, MSH2, TP53

Molecular functions related to Keratoacanthoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1guanine/thymine mispair bindingGO:00321379.8MLH1, MSH2

Sources for Keratoacanthoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet