MCID: KRT023
MIFTS: 16

Keratoderma Palmoplantaris Transgrediens malady

Genetic diseases, Rare diseases, Skin diseases categories

Aliases & Classifications for Keratoderma Palmoplantaris Transgrediens

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 26ICD10 via Orphanet
See all sources

Keratoderma Palmoplantaris Transgrediens, Aliases & Descriptions:

Name: Keratoderma Palmoplantaris Transgrediens 41 60
Greither Disease 41 47 60
Keratosis Palmoplantaris Transgrediens Et Progrediens 41 47
Transgrediens Et Progrediens Palmoplantar Keratoderma 41 47
Keratosis Extremitatum Hereditaria Progrediens 41 47
Progressive Diffuse Palmoplantar Keratoderma 41 47
 
Transgrediens Et Progrediens Ppk 41 47
Progressive Diffuse Ppk 41 47
Erythrokeratodermia Figurata, Congenital Familial, in Plaques 41
Erythrokeratodermia Variabilis with Erythema Gyratum Repens 41
Greither's Disease 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Skin diseases
Orphanet: 47 
Rare skin diseases


External Ids:

Orphanet47 495
ICD10 via Orphanet26 Q82.8

Summaries for Keratoderma Palmoplantaris Transgrediens

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MalaCards based summary: Keratoderma Palmoplantaris Transgrediens, also known as greither disease, is related to erythrokeratodermia variabilis et progressiva and keratoderma, and has symptoms including dry skin, palmoplantar keratoderma and hyperhidrosis. Affiliated tissues include skin.

Related Diseases for Keratoderma Palmoplantaris Transgrediens

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Diseases related to Keratoderma Palmoplantaris Transgrediens via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1erythrokeratodermia variabilis et progressiva10.4
2keratoderma10.1

Symptoms for Keratoderma Palmoplantaris Transgrediens

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Symptoms:

 47 (show all 10)
  • palmoplantar hyperkeratosis/keratoderma
  • dry/squaly skin/exfoliation
  • autosomal dominant inheritance
  • hyperhidrosis/increased sweating
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • thin/hypoplastic/hyperconvex fingernails
  • corneal dystrophy
  • hyperkeratosis/ainhum/hyperkeratotic skin fissures
  • alopecia
  • restricted joint mobility/joint stiffness/ankylosis

HPO human phenotypes related to Keratoderma Palmoplantaris Transgrediens:

(show all 7)
id Description Frequency HPO Source Accession
1 dry skin hallmark (90%) HP:0000958
2 palmoplantar keratoderma hallmark (90%) HP:0000982
3 hyperhidrosis typical (50%) HP:0000975
4 abnormality of the fingernails typical (50%) HP:0001231
5 corneal dystrophy occasional (7.5%) HP:0001131
6 limitation of joint mobility occasional (7.5%) HP:0001376
7 alopecia occasional (7.5%) HP:0001596

Drugs & Therapeutics for Keratoderma Palmoplantaris Transgrediens

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Drug clinical trials:

Search ClinicalTrials for Keratoderma Palmoplantaris Transgrediens

Search NIH Clinical Center for Keratoderma Palmoplantaris Transgrediens

Genetic Tests for Keratoderma Palmoplantaris Transgrediens

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Anatomical Context for Keratoderma Palmoplantaris Transgrediens

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MalaCards organs/tissues related to Keratoderma Palmoplantaris Transgrediens:

31
Skin

Animal Models for Keratoderma Palmoplantaris Transgrediens or affiliated genes

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Publications for Keratoderma Palmoplantaris Transgrediens

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Variations for Keratoderma Palmoplantaris Transgrediens

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Expression for genes affiliated with Keratoderma Palmoplantaris Transgrediens

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Search GEO for disease gene expression data for Keratoderma Palmoplantaris Transgrediens.

Pathways for genes affiliated with Keratoderma Palmoplantaris Transgrediens

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Compounds for genes affiliated with Keratoderma Palmoplantaris Transgrediens

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GO Terms for genes affiliated with Keratoderma Palmoplantaris Transgrediens

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Products for genes affiliated with Keratoderma Palmoplantaris Transgrediens

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Keratoderma Palmoplantaris Transgrediens

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet