MCID: KRT002
MIFTS: 41

Keratomalacia malady

Rare diseases, Metabolic diseases categories

Aliases & Classifications for Keratomalacia

About this section

Summaries for Keratomalacia

About this section


MedlinePlus:32 Vitamin a plays a role in your vision bone growth reproduction cell functions immune system vitamin a is an antioxidant. it can come from plant or animal sources. plant sources include colorful fruits and vegetables. animal sources include liver and whole milk. vitamin a is also added to foods like cereals. vegetarians, young children, and alcoholics may need extra vitamin a. you might also need more if you have certain conditions, such as liver diseases, cystic fibrosis, and crohn's disease. check with your health care provider to see if you need to take vitamin a supplements. nih: national institutes of health office of dietary supplements

MalaCards based summary: Keratomalacia, also known as vitamin a deficiency, is related to xerophthalmia and night blindness. An important gene associated with Keratomalacia is RHO (rhodopsin). The drugs cod liver oil and vitamin a and the compounds amine and acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include liver, eye and bone.

Wikipedia:63 Keratomalacia is an eye disorder that results from Vitamin A deficiency. Vitamin A is required to... more...

Related Diseases for Keratomalacia

About this section

Diseases related to Keratomalacia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 333)
idRelated DiseaseScoreTop Affiliating Genes
1xerophthalmia30.2RHO, DNASE1L1
2night blindness11.3
3congenital stationary night blindness11.2
4x-linked congenital stationary night blindness10.9
5retinitis10.7
6autosomal dominant congenital stationary night blindness10.6
7autosomal recessive congenital stationary night blindness10.6
8hereditary night blindness10.6
9retinitis pigmentosa10.6
10night blindness, congenital stationary , 1e, autosomal recessive10.5
11night blindness, congenital stationary , 1d, autosomal recessive10.5
12night blindness, congenital stationary , 1a, x-linked10.5
13night blindness, congenital stationary , 1f, autosomal recessive10.5
14night blindness, congenital stationary , 1b, autosomal recessive10.5
15night blindness, congenital stationary , 2b, autosomal recessive10.5
16night blindness, congenital stationary , 1c, autosomal recessive10.5
17myopia10.5
18leukemia10.5
19night blindness, congenital stationary, autosomal dominant 310.5
20night blindness, congenital stationary, autosomal dominant 110.5
21night blindness, congenital stationary, autosomal dominant 210.5
22night blindness, congenital stationary , 2a, x-linked10.5
23acquired night blindness10.5
24pityriasis rubra pilaris10.5
25choroideremia10.4
26amyloidosis10.4
27myeloma10.4
28al amyloidosis10.4
29plasma cell leukemia10.4
30fundus albipunctatus10.4
31chorioretinitis10.4
32night blindness - skeletal anomalies - dysmorphism10.4
33multiple myeloma10.4
34hereditary hypercarotenemia and vitamin a deficiency10.4
35keratoconjunctivitis sicca10.4
36vascular dementia10.3
37dementia10.3
38night blindness skeletal anomalies unusual facies10.3
39bronchopulmonary dysplasia10.3
40hypercarotenemia and vitamin a deficiency, autosomal dominant10.3
41obesity10.3
42cone-rod dystrophy10.3
43usher syndrome, type 3a10.3
44gyrate atrophy of choroid and retina with or without ornithinemia10.3
45melanoma10.3
46woods black norbury syndrome10.3
47cacna1f-related x-linked congenital stationary night blindness10.3
48nyx-related x-linked congenital stationary night blindness10.3
49chondroectodermal dysplasia with night blindness10.3
50leukoplakia10.3

Graphical network of the top 20 diseases related to Keratomalacia:



Diseases related to keratomalacia

Symptoms for Keratomalacia

About this section

Drugs & Therapeutics for Keratomalacia

About this section

Genetic Tests for Keratomalacia

About this section

Anatomical Context for Keratomalacia

About this section

MalaCards organs/tissues related to Keratomalacia:

31
Liver, Eye, Bone, Pancreas, Skin

Animal Models for Keratomalacia or affiliated genes

About this section

Publications for Keratomalacia

About this section

Articles related to Keratomalacia:

(show top 50)    (show all 60)
idTitleAuthorsYear
1
Severe keratomalacia after 12 months of continuous hydrogel contact lens wear in a psychiatric patient. (25467290)
2015
2
Xerophthalmia and keratomalacia secondary to diet-induced vitamin A deficiency in Scottish adults. (24513368)
2014
3
Porcine urinary bladder extracellular matrix grafts (ACell Vet(Ar) Corneal Discs) for keratomalacia in 17 equids (2012-2013). (25429917)
2014
4
Sociodemographic features and risk factor profile of keratomalacia in early infancy. (22406941)
2012
5
360-degree conjunctival grafting for management of diffuse keratomalacia in a dog. (21521447)
2011
6
Ciliary hypertrichosis in a child with keratomalacia. (21092399)
2010
7
Use of amniotic membrane graft and corneal transplantation in a patient with bilateral keratomalacia induced by uncontrolled phenylketonuria. (17525666)
2007
8
Keratomalacia caused by psychiatric-induced dietary restrictions. (17721303)
2007
9
Equine amniotic membrane transplantation for corneal ulceration and keratomalacia in three horses. (16178841)
2005
10
Keratomalacia in a neonate secondary to maternal vitamin A deficiency. (16272665)
2005
11
Advanced keratomalacia with descemetocele in an infant with cystic fibrosis. (16009849)
2005
12
Inflammatory stromal keratopathies: medical management of stromal keratomalacia, stromal abscesses, eosinophilic keratitis, and band keratopathy in the horse. (15271427)
2004
13
Keratoplasty for keratomalacia in preschool children. (12714386)
2003
14
Keratomalacia and scurvy in a severely malnourished infant. (11860588)
2002
15
Bilateral keratomalacia in a cachectic scleroderma patient. (10692938)
1999
16
Keratomalacia in northern Afghanistan. (17492034)
1998
17
A new classification system predicting keratomalacia after trauma in vitamin A deficiency: sodium citrate does not prevent disease progression. (9220247)
1997
18
Xerophthalmia, keratomalacia and nutritional blindness. (2188921)
1990
19
Keratomalacia in a child with familial hypo-retinol-binding proteinemia. (3148050)
1988
20
Keratomalacia in Soyal fed infants. (3448023)
1987
21
Keratomalacia on a 'healthy diet'. (3516209)
1986
22
Vitamin A to prevent keratomalacia. (6149410)
1984
23
Nutritional factors in corneal xerophthalmia and keratomalacia. (7065955)
1982
24
Corneal xerophthalmia and keratomalacia. (7150067)
1982
25
Corneal xerophthalmia and keratomalacia. (7065956)
1982
26
Keratomalacia in acrodermatitis enteropathica (AE). (6796792)
1981
27
Role of vitamin A deficiency and protein-calorie malnutrition in keratomalacia and Bitot's spots (A clinicopathologic study). (120319)
1979
28
Keratomalacia in the cachectic hospitalized patient. (986773)
1976
29
Keratomalacia. (1081744)
1975
30
Therapeutic penetrating keratoplasty in keratomalacia. (4585797)
1973
31
Keratomalacia in Haiti. (4647770)
1972
32
Clinical aspects of keratomalacia. (4647768)
1972
33
Clinical aspects of keratomalacia. (4630594)
1972
34
Surgical treatment of active keratomalacia by "covering graft". (4567293)
1972
35
Keratomalacia and intestinal helminthiasis. (4644282)
1972
36
Serum proteins in kwashiorkor and marasmus. 4. Cases with or without keratomalacia. (5401879)
1969
37
Necrotizing keratitis (keratomalacia) with corneal perforation and expulsive uveal hemorrhage in a new-born. (5755680)
1968
38
The evolution of keratomalacia. (5255226)
1967
39
Keratomalacia: a review of its relationship to xerophthalmia and its response to treatment. (6037438)
1967
40
Xerophthalmia (keratomalacia) in Singapore--a study. (5587801)
1967
41
Keratomalacia following senile cataract extraction. (5830426)
1965
42
KERATOMALACIA IN KWASHIORKOR AND MARASMUS. (14281021)
1964
43
Protein deficiency in keratomalacia. (13364173)
1956
44
Keratomalacia: causes, diagnosis, treatment and prevention. (13212074)
1954
45
A CASE OF KERATOMALACIA CURED BY PENICILLIN AND VITAMIN A. (18170469)
1948
46
Xerophthalmia and keratomalacia in children. (20257859)
1947
47
ON THE PIGMENTATION OF THE CONJUNCTIVA IN NORMAL INDIVIDUALS AND IN CASES OF KERATOMALACIA IN ADULTS. (18168928)
1931
48
AN INQUIRY INTO THE ORIGIN OF THE ABNORMAL PIGMENTATION OF THE SKIN AND CONJUNCTIVA IN CASES OF KERATOMALACIA IN ADULTS. (18168824)
1929
49
KERATOMALACIA IN SOUTHERN INDIA. (18168192)
1922
50
A Contribution to the Study of Keratomalacia among Rats. (16742953)
1920

Variations for Keratomalacia

About this section

Expression for genes affiliated with Keratomalacia

About this section
Search GEO for disease gene expression data for Keratomalacia.

Pathways for genes affiliated with Keratomalacia

About this section

Compounds for genes affiliated with Keratomalacia

About this section
Sources:
43Novoseek, 49PharmGKB, 28IUPHAR, 24HMDB, 12DrugBank
See all sources

Compounds related to Keratomalacia according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1amine439.2QDPR, RHO
2acetylcholine43 49 28 24 1213.2QDPR, RHO
3gtp43 2810.1QDPR, RHO
4hydrogen43 2410.1QDPR, RHO
5dopamine43 28 24 1212.0RHO, QDPR
6lipid439.0QDPR, RHO
7threonine438.9QDPR, RHO
8alanine438.7QDPR, RHO

GO Terms for genes affiliated with Keratomalacia

About this section

Products for genes affiliated with Keratomalacia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Keratomalacia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet