Aliases & Classifications for Keratopathy

About this section

Aliases & Descriptions for Keratopathy:

Name: Keratopathy 32 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:2283
NCIt42 C27012
UMLS65 C0235270

Summaries for Keratopathy

About this section
MalaCards based summary: Keratopathy is related to palindromic rheumatism and bullous keratopathy. An important gene associated with Keratopathy is PAX6 (Paired Box 6), and among its related pathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Cardiac Progenitor Differentiation. Affiliated tissues include endothelial, eye and breast, and related mouse phenotypes are renal/urinary system and respiratory system.

Related Diseases for Keratopathy

About this section

Graphical network of the top 20 diseases related to Keratopathy:



Diseases related to keratopathy

Symptoms for Keratopathy

About this section

Drugs & Therapeutics for Keratopathy

About this section

Drugs for Keratopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 87)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Pharmaceutical SolutionsPhase 4, Phase 3, Phase 2, Phase 17004
2
AcetylcholineexperimentalPhase 2, Phase 368951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride
3Peripheral Nervous System AgentsPhase 2, Phase 3, Phase 118510
4TetrahydrozolinePhase 3, Phase 1, Phase 2542
5Ophthalmic SolutionsPhase 3, Phase 1, Phase 21006
6Neuromuscular AgentsPhase 2, Phase 3922
7IncobotulinumtoxinAPhase 2, Phase 3599
8Neurotransmitter AgentsPhase 2, Phase 314795
9OnabotulinumtoxinAPhase 2, Phase 3588
10Botulinum ToxinsPhase 2, Phase 3616
11Cholinergic AgentsPhase 2, Phase 33243
12Botulinum Toxins, Type APhase 2, Phase 3588
13AbobotulinumtoxinAPhase 2, Phase 3588
14
AmbroxolapprovedPhase 1, Phase 21318683-91-52132
Synonyms:
4-(((2-Amino-3,5-dibromophenyl)methyl)amino)cyclohexanol
4-(2-Amino-3,5-dibromo-benzylamino)-cyclohexanol
4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol
Amboxol
Ambroxol
Ambroxol Hydrochloride
Ambroxol hcl
Ambroxolum
Bisolvon metabolite vIII
 
Bromhexine metabolite vIII
Bromhexine-metabolite vIII
N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol
N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol
SID29215331
SID50085991
Tabcin
Tabcin (TN)
trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol
trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol
15
EphedrineapprovedPhase 1, Phase 2447299-42-39294
Synonyms:
( )-Pseudoephedrine
(+)-Ephedrin
(+)-Ephedrine
(+)-Pseudoephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(+-)-Ephedrine
(-)-Ephedrine
(-)-Pseudoephedrine
(-)-psi-Ephedrine
(-)-threo-Ephedrine
(1R,2R)-Ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2R)-Ephedrine
(L)-EPHEDRINE
--EPHEDRINE
1-EPHEDRINE
1-Sedrin
134910_ALDRICH
287636_ALDRICH
287644_ALDRICH
299-42-3
304-87-0
30987-59-8
321-96-0
321-97-1
321-98-2
37577-31-4
38732-95-5
45261_FLUKA
4607-45-8
50-98-6
50906-05-3
53214-57-6
649031_ALDRICH
6912-63-6
7009-81-6
90-82-4
968-63-8
AC-20231
AC-20292
AC1L1JGK
AC1L1NUA
AC1L1RFA
AC1L1SR1
AC1L1T31
AC1L1Y3M
AC1O8JUO
AC1Q3XJE
AC1Q3XJM
AC1Q3XJN
AC1Q59F5
AC1Q7701
AI3-02761
AKOS000268842
AR-1A0126
AR-1I7143
Acunaso
Acunaso (TN)
Afrinol
Ambap299-42-3
BIDD:GT0817
BRN 3197916
BRN 4231286
BSPBio_001946
BSPBio_001968
BSPBio_003261
Benylin Decongestant
Besan
Biophedrin
C01575
C02765
C10H15NO
CHEBI:15407
CHEBI:51209
CHEMBL1590
CHEMBL211456
CHEMBL357080
CID11972440
CID5032
CID62946
CID6710657
CID7028
CID8650
CID9294
CID9457
CPD-9954
CPDD 0049
Cenafed
D00124
D08449
DB00852
DB01364
Decofed
DivK1c_000181
DivK1c_000451
DivK1c_000461
Drixoral N.D.
EINECS 202-017-0
EINECS 202-018-6
EINECS 206-080-5
EINECS 206-292-8
EINECS 206-293-3
Eciphin
Efedrin
Efidac/24
Eltor 120
Ephedral
Ephedremal
Ephedrin
Ephedrine
Ephedrine (TN)
Ephedrine (USP)
Ephedrine [USAN:BAN]
Ephedrine l-form
Ephedrital
Ephedrol
Ephedrosan
Ephedrotal
Ephedsol
Ephendronal
Ephoxamin
Fedrin
Genaphed
HSDB 3072
HSDB 3177
I-Sedrin
I01-3584
I01-8925
I01-8928
 
IDI1_000181
IDI1_000451
IDI1_000461
Isoephedrine
Jsp005664
KBio1_000181
KBio1_000451
KBio1_000461
KBio2_001358
KBio2_001500
KBio2_003926
KBio2_004068
KBio2_006494
KBio2_006636
KBio3_001188
KBio3_001446
KBio3_002762
KBioGR_001013
KBioGR_001763
KBioSS_001358
KBioSS_001500
KST-1A9168
Kratedyn
L(+)-psi-Ephedrine
L(-)-Ephedrine
L-(+)-Ephedrine
L-(-)-Ephedrine
L-Ephedrine
L-erythro-2-(Methylamino)-1-phenylpropan-1-ol
L000968
LS-125921
LS-125922
LS-43083
LS-63961
LS-63962
LS-63963
LS-63964
Lexofedrin
Lopac-E-3250
Lopac0_000501
MLS000069657
Manadrin
Mandrin
Maxenal
MolPort-001-684-474
MolPort-001-684-477
MolPort-001-684-478
MolPort-001-684-479
MolPort-001-769-085
Myfedrine
NCGC00015408-01
NCGC00015408-02
NCGC00162174-01
NCGC00178180-01
NCGC00178889-01
NCI-C55652
NCI60_002955
NINDS_000181
NINDS_000451
NINDS_000461
NSC 165609
NSC 170951
NSC 8971
NSC165609
NSC170951
NSC8971
Nasol
Neodurasina
Neodurasina (TN)
Oprea1_287330
PDSP1_000168
PDSP1_001106
PDSP1_001343
PDSP1_001345
PDSP1_001346
PDSP1_001347
PDSP2_000167
PDSP2_001090
PDSP2_001327
PDSP2_001329
PDSP2_001330
PDSP2_001331
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoephedrine (D)
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
Robidrine
SMR000059174
SPBio_000214
SPBio_001365
SPBio_001377
ST023802
STK367993
STOCK1N-42675
Sanedrine
Spectrum2_000137
Spectrum2_001303
Spectrum2_001309
Spectrum3_000414
Spectrum3_000563
Spectrum3_001771
Spectrum4_000497
Spectrum4_001162
Spectrum5_000650
Spectrum5_000879
Spectrum5_001106
Spectrum_000878
Spectrum_001020
Sudafed
Sudafed Decongestant
UNII-03VRY66076
UNII-7CUC9DDI9F
UNII-GN83C131XS
Vencipon
WLN: QYR & Y1 & M1
WLN: QYR&Y1&M1
Zephrol
d-Ephedrine
d-Isoephedrine
d-Pseudoephedrine
d-psi-Ephedrine
l-Ephedrine
l-Pseudoephedrine
racephedrine
trans-Ephedrine
16
MethylprednisoloneapprovedPhase 2108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
17
PseudoephedrineapprovedPhase 1, Phase 244790-82-47028
Synonyms:
( )-Pseudoephedrine
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
(1S,2S)-2-Methylamino-1-phenyl-1-propanol
(1S,2S)-Pseudoephedrine
(1S,2S)-Pseudoephedrine, polymer-bound
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
287636_ALDRICH
304-87-0
30987-59-8
37577-31-4
649031_ALDRICH
90-82-4
AC-20292
AC1L1NUA
Acunaso
Acunaso (TN)
Afrinol
BIDD:GT0817
BRD-K84175871-003-02-2
BSPBio_003261
Balminil Decongestant Syrup
Benylin Decongestant
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alpha-S)- (9CI)
Besan
C02765
C10H15NO
CHEBI:51209
CHEMBL1590
CID7028
CPD-9954
Cenafed
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-Methylamino-1-phenyl-1-propanol
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-Ephedrine
D-Psi-ephedrine
D08449
DB00852
Decofed
Dimetapp Decongestant
Dimetapp Decongestant Pediatric Drops
DivK1c_000451
Drixoral N.D.
Drixoral Nasal Decongestant
EINECS 202-018-6
Efidac 24 Pseudoephedrine Hcl
Efidac/24
Eltor 120
Ephed 60
Ephedrine
Genaphed
HSDB 3177
I01-8928
IDI1_000451
Isoephedrine
KBio1_000451
 
KBio2_001358
KBio2_003926
KBio2_006494
KBio3_002762
KBioGR_001763
KBioSS_001358
L(+)-Psi-Ephedrine
L(+)-Psi-ephedrine
L(+)-psi-Ephedrine
L-(+)-Pseudoephedrine
LS-125922
Lopac-E-3250
Maxenal
MolPort-001-684-474
Myfedrine
NCGC00015408-01
NCGC00178180-01
NCI60_002955
NINDS_000451
Neodurasina
Neodurasina (TN)
Novafed
PDSP1_001347
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoefedrina [INN-Spanish]
Pseudoephedrine
Pseudoephedrine (D)
Pseudoephedrine (INN)
Pseudoephedrine D-form
Pseudoephedrine Ephedrine
Pseudoephedrine Hydrochloride
Pseudoephedrine [INN:BAN]
Pseudoephedrine d-form
Pseudoephedrine hydrochloride
Pseudoephedrine sulfate
Pseudoephedrinum
Pseudoephedrinum [INN-Latin]
Psi-ephedrin
Psi-ephedrine
Robidrine
SPBio_001365
STOCK1N-42675
Spectrum2_001303
Spectrum3_001771
Spectrum4_001162
Spectrum5_000650
Spectrum_000878
Sudafed
Sudafed Decongestant
Sudafed Decongestant 12 Hour
Sudafed Decongestant Extra Strength
Suphedrine
Triaminic AM Decongestant Formula
Triaminic Infant Oral Decongestant Drops
UNII-7CUC9DDI9F
alpha-(1-(Methylamino)ethyl)benzyl alcohol
d-Isoephedrine
d-Pseudoephedrine
d-psi-2-Methylamino-1-phenyl-1-propanol
d-psi-Ephedrine
trans-Ephedrine
18
FluorometholoneapprovedPhase 217426-13-19878
Synonyms:
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11beta,17alpha-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
426-13-1
9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
AC-3520
AC1L1U0Y
AI3-52813
Alcon Brand of Fluorometholone
Allergan Brand 1 of Fluorometholone
Allergan Brand 2 of Fluorometholone
Allergan Brand 3 of Fluorometholone
BPBio1_001029
BRD-K64862097-001-03-9
BSPBio_000935
CHEMBL1200600
CID9878
Cortilet
Cortisdin
D005469
D01367
DB00324
Delmeson
EINECS 207-041-5
Efflumidex
F0414
F9381_SIGMA
FML
FML Forte
FML Liquifilm
FML S.O.P
FML-S Liquifilm
Flarex
Fluaton
Flucon
Flucon, Isopto
Flumetholon
Fluor Op
Fluor-OP
Fluor-Op
Fluor-op (TN)
Fluormetholon
Fluormetholone
Fluormetholonum
Fluoro Ophtal
Fluoro-Ophtal
Fluoromethalone
Fluorometholon
Fluorometholone
Fluorometholone (JP15/USP/INN)
 
Fluorometholone Acetate
Fluorometholone [INN:BAN:JAN]
Fluorometholonum
Fluorometholonum [INN-Latin]
Fluorometolona
Fluorometolona [INN-Spanish]
Fluorometolone
Fluorometolone [DCIT]
Fluorométholone
Fluoropos
Fml
Fml (TN)
Fml Forte
HMS1570O17
Isdin Brand of Fluorometholone
Isopto Flucon
LS-118455
Loticort
MLS000069537
MLS001076157
MolPort-003-941-413
NCGC00021575-03
NCI60_002886
NSC 33001
NSC-33001
NSC33001
Neo-Oxylone
Novartis Brand of Fluorometholone
Oxylone
Oxylone (TN)
PMS Fluorometholone
PMS-Fluorometholone
Pharm Allergan Brand of Fluorometholone
Pharm-Allergan Brand of Fluorometholone
Pharmascience Brand of Fluorometholone
Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl- (8CI)
Prestwick0_000718
Prestwick1_000718
Prestwick2_000718
Prestwick3_000718
Prestwick_227
SMR000058598
SPBio_002856
Trilcin
U 8614
UNII-SV0CSG527L
Ursapharm Brand of Fluorometholone
Ursnon
Winzer Brand of Fluorometholone
ZINC03876158
component of Neo-Oxylone
fluorometholone
19
PrednisoloneapprovedPhase 2108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
20
Bevacizumabapproved, investigationalPhase 21875216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
21Nasal DecongestantsPhase 1, Phase 2414
22Prednisolone phosphatePhase 21082
23Protective AgentsPhase 25651
24Prednisolone hemisuccinatePhase 21082
25Angiogenesis Modulating AgentsPhase 23611
26Angiogenesis InhibitorsPhase 23688
27ExpectorantsPhase 1, Phase 2337
28Vasoconstrictor AgentsPhase 1, Phase 21303
29Respiratory System AgentsPhase 1, Phase 23931
30HormonesPhase 211748
31Antineoplastic Agents, HormonalPhase 24256
32Gastrointestinal AgentsPhase 26401
33Anti-Inflammatory AgentsPhase 28478
34AntiemeticsPhase 23213
35AnestheticsPhase 27385
36Anti-Allergic AgentsPhase 21312
37Prednisolone acetatePhase 21082
38glucocorticoidsPhase 23896
39Methylprednisolone HemisuccinatePhase 21082
40Neuroprotective AgentsPhase 21376
41Hormone AntagonistsPhase 210002
42Methylprednisolone acetatePhase 21082
43Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 29988
44ImmunoglobulinsPhase 24477
45MitogensPhase 21386
46Antibodies, MonoclonalPhase 22413
47AntibodiesPhase 24477
48Endothelial Growth FactorsPhase 2328
49Anti-Infective AgentsPhase 117220
50Antiprotozoal AgentsPhase 11730

Interventional clinical trials:

(show all 32)
idNameStatusNCT IDPhase
1Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision LensesCompletedNCT01268306Phase 4
2Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic KeratopathyRecruitingNCT02600429Phase 3
3Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye DiseaseRecruitingNCT00370734Phase 2, Phase 3
4Amniotic Membrane Graft In Syntomathic Bullous KeratopathyCompletedNCT01926535Phase 2
5Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)CompletedNCT01448213Phase 2
6Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal HealingCompletedNCT02746848Phase 1, Phase 2
7Effects of Oral Mucolytics on Tear Film and Ocular SurfaceCompletedNCT01713179Phase 1, Phase 2
8Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)RecruitingNCT01808378Phase 2
9Study of Ataluren in Patients With AniridiaRecruitingNCT02647359Phase 2
10Bevacizumab for the Treatment of Corneal NeovascularizationActive, not recruitingNCT00992849Phase 2
11A Randomized, Controlled, Double-masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) PatientsSuspendedNCT01972438Phase 1, Phase 2
12Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)RecruitingNCT02658435Phase 1
13Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous KeratopathyCompletedNCT00659308
14The Effects of Riboflavin/ Ultraviolet-A Corneal Cross-linking on the Signs and Symptoms of Bullous KeratopathyCompletedNCT01106274
15Automated Lamellar Keratectomy in Symptomatic Patients With Bullous KeratopathyCompletedNCT00654888
16Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal NeovasculizationCompletedNCT00681603
17A Comparison of Hydrogel Dressings and Ocular Lubricants in the Prevention on Corneal Damage in the Critically IllCompletedNCT00513734
18Comparison of Patient Comfort After Two Anesthetic Protocols for Injections Into the EyeCompletedNCT01087489
19Eyelash Line Resection for Entropion Associated With Down's SyndromeCompletedNCT01758718
20Correlation of Gene Abnormalities and Clinical Manifestations of AniridiaCompletedNCT00265590
21Long-term Topical Cyclosporine for Atopic KeratoconjunctivitisCompletedNCT00987467
22The SNEC DSAEK EndoGlide Clinical TrialRecruitingNCT01122043
23Staged and Combined Surgery for Cataract Patients With Corneal Endothelial DysfunctionRecruitingNCT02523950
24Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)RecruitingNCT02020044
25Study of Endothelial Keratoplasty OutcomesRecruitingNCT00800111
26Comparing Endoglide to Endoserter for DSAEK Graft InsertionRecruitingNCT01791075
27Corneal Transplantation Guided by OCT RESCANNot yet recruitingNCT02736877
28Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture MediaNot yet recruitingNCT00623584
29Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal EdemaNot yet recruitingNCT02660151
30Comparison of Aqueous and Plasma Glucose Level in Diabetic PatientsNot yet recruitingNCT02750098
31Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal EdemaNot yet recruitingNCT01890252
32Topical Steroid Treatment After Posterior Lamellar Corneal TransplantationWithdrawnNCT01682421

Search NIH Clinical Center for Keratopathy

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Keratopathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Keratopathy:
Adipose-derived stem cells for treatment of bilateral limbic-associated keratopathy
Embryonic/Adult Cultured Cells Related to Keratopathy:
Adipose-derived stem cells

Genetic Tests for Keratopathy

About this section

Anatomical Context for Keratopathy

About this section

MalaCards organs/tissues related to Keratopathy:

33
Endothelial, Eye, Breast, Liver, Lung, Thyroid, Brain

Animal Models for Keratopathy or affiliated genes

About this section

MGI Mouse Phenotypes related to Keratopathy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.8AKR1B1, IGF1, PAX6, TGFB1, TGFB2
2MP:00053888.6IGF1, PAX6, TGFB1, TGFB2, TGFB3
3MP:00053827.7MBD5, PAX6, TGFB1, TGFB2, TGFB3
4MP:00053917.3AKR1B1, CYP1B1, KRT12, NID1, PAX6, TGFB1
5MP:00053907.2AKR1B1, IGF1, MBD5, PAX6, TGFB1, TGFB2
6MP:00053856.9IGF1, MBD5, NID1, PAX6, TGFB1, TGFB2
7MP:00053766.3AKR1B1, CYP1B1, IGF1, MBD5, NLRP1, PAX6

Publications for Keratopathy

About this section

Articles related to Keratopathy:

(show top 50)    (show all 689)
idTitleAuthorsYear
1
Divalproex sodium leading to sustained significant improvement in tardive dyskinesia in a patient with bipolar disorder. (26985118)
2016
2
Understanding West Nile virus ecology in Europe: Culex pipiens host feeding preference in a hotspot of virus emergence. (25888754)
2015
3
A Case of Neuromyelitis Optica Masquerading as Miller Fisher Syndrome. (25408664)
2014
4
LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts. (24583087)
2014
5
Desmocollina892 affects the adhesive strength and cytoskeletal arrangement in esophageal squamous cell carcinoma cells. (25119898)
2014
6
Unusual venous thrombosis in a 35-year-old man. (24167216)
2014
7
Isolated splenomegaly as the only presentation of systemic mastocytosis. (23604430)
2013
8
Coping and Coping Assistance Among Children With Sickle Cell Disease and Their Parents. (24327131)
2013
9
Correction of postaxial metatarsal polydactyly of the foot by percutaneous ray amputation and osteotomy. (23063205)
2013
10
Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a I^2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells. (22167199)
2012
11
What lies beneath: an unusual case of tuberculous osteomyelitis. (22645216)
2012
12
A reformulated spherule-derived coccidioidin (Spherusol) to detect delayed-type hypersensitivity in coccidioidomycosis. (22669545)
2012
13
Acoustic neuroma neurophysiologic correlates: vestibular-preoperative, intraoperative, and postoperative. (22483818)
2012
14
Expression form of p53 and PCNA at the invasive front in oral squamous cell carcinoma: correlation with clinicopathological features and prognosis. (21501231)
2011
15
Solitary juvenile xanthogranuloma in the lung of a young adult. (21753717)
2011
16
Giant cell tumor of the metacarpal bones. (21886934)
2011
17
Diagnosis of medial plica syndrome of the knee with dynamic sonography. (20445372)
2010
18
Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. (18583570)
2009
19
Clinical features and long-term outcome of nephrotic syndrome associated with heterozygous NPHS1 and NPHS2 mutations. (19406966)
2009
20
Central large pulmonary arteriovenous malformation with aneurysmal dilatation. (19795336)
2009
21
Impact of glutathione S-transferase M1 and T1 gene polymorphisms on the smoking-related coronary artery disease. (18583868)
2008
22
New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome. (18550699)
2008
23
IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma. (17591896)
2007
24
Plasma cytokine and soluble receptor signature predicts outcome of patients with classical Hodgkin's lymphoma: a study from the Groupe d'Etude des Lymphomes de l'Adulte. (17389336)
2007
25
The influence of garlic (Allium sativum) extract on interleukin 1alpha-induced expression of endothelial intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. (16492524)
2006
26
Identification of the N-linked glycosylation sites of vitamin K-dependent carboxylase and effect of glycosylation on carboxylase function. (17144668)
2006
27
The coracoacromial ligament: morphology and study of acromial enthesopathy. (16194749)
2005
28
Mutation, loss of heterozygosity, and expression of tumor suppressor gene ING1 in sporadic colorectal carcinoma]. (15694021)
2005
29
Estimating the probability of cancer with several tumor markers in patients with colorectal disease. (15218297)
2004
30
Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21. (15354323)
2004
31
HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells. (14515355)
2003
32
Bone and In-111 octreotide imaging in oncogenic osteomalacia: a case report. (12170004)
2002
33
A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling. (12426372)
2002
34
Incidence of a second tumor in hypopituitary patients operated for pituitary tumors. (11158027)
2001
35
Proteinases, their inhibitors, and cytokine profiles in acute wound fluid. (11115151)
2000
36
Expression of interleukin (IL)-12 (p40) and IL-12 (beta 2) receptors in allergic rhinitis and chronic sinusitis. (10520052)
1999
37
Triiodothyronine enhances expression of the interleukin-2 receptor alpha chain. (10503997)
1999
38
Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome. (10072440)
1999
39
A novel KIT gene missense mutation in a Japanese family with piebaldism. (9699740)
1998
40
Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors. (9614197)
1998
41
The influence of chronic hypokalemia on myocardial adrenergic receptor densities: enhanced sensitivity to epinephrine-induced arrhythmias. (9085948)
1997
42
Jun and Fos regulation of NAD(P)H: quinone oxidoreductase gene expression. (8004128)
1994
43
Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review. (8411230)
1993
44
Characterization of the serpin, alpha 1-antichymotrypsin, in normal human cerebrospinal fluid. (1727448)
1992
45
Nephrocalcinosis in the rat: a literature review. (1620876)
1992
46
Unusual association: Dandy-Walker-like malformation in the Rubinstein-Taybi syndrome. (2801779)
1989
47
Importance of cholesterol-phospholipid interaction in determining dynamics of normal and abetalipoproteinemia red blood cell membrane. (6168375)
1981
48
Treatment of paralytic ileus with adrenergic neuronal blocking drugs. (4928770)
1971
49
What is chronic pyelonephritis? (5551266)
1971
50
Scarlet Fever: An Effort in Preventive Medicine. (19988875)
1932

Variations for Keratopathy

About this section

Expression for genes affiliated with Keratopathy

About this section
Search GEO for disease gene expression data for Keratopathy.

Pathways for genes affiliated with Keratopathy

About this section

Pathways related to Keratopathy according to GeneCards Suite gene sharing:

(show all 40)
idSuper pathwaysScoreTop Affiliating Genes
19.5IGF1, PAX6, TGFB1
29.5IGF1, PAX6, TGFB1
39.4TGFB1, TGFB3
4
Show member pathways
9.4TGFB1, TGFB3
5
Show member pathways
9.4AKR1B1, IGF1, TGFB1
69.4AKR1B1, IGF1, TGFB1
79.2IGF1, TGFB1, TGFB2
89.2IGF1, TGFB1, TGFB2
98.9TGFB1, TGFB2, TGFB3
10
Show member pathways
8.9TGFB1, TGFB2, TGFB3
118.9TGFB1, TGFB2, TGFB3
128.9TGFB1, TGFB2, TGFB3
138.9TGFB1, TGFB2, TGFB3
14
Show member pathways
8.9TGFB1, TGFB2, TGFB3
15
Show member pathways
8.9TGFB1, TGFB2, TGFB3
168.9TGFB1, TGFB2, TGFB3
178.9TGFB1, TGFB2, TGFB3
188.9TGFB1, TGFB2, TGFB3
19
Show member pathways
8.9TGFB1, TGFB2, TGFB3
20
Show member pathways
8.9TGFB1, TGFB2, TGFB3
218.9TGFB1, TGFB2, TGFB3
22
Show member pathways
8.9TGFB1, TGFB2, TGFB3
23
Show member pathways
8.9TGFB1, TGFB2, TGFB3
248.9TGFB1, TGFB2, TGFB3
258.9TGFB1, TGFB2, TGFB3
268.9TGFB1, TGFB2, TGFB3
27
Show member pathways
8.9TGFB1, TGFB2, TGFB3
288.9TGFB1, TGFB2, TGFB3
298.9TGFB1, TGFB2, TGFB3
30
Show member pathways
8.9TGFB1, TGFB2, TGFB3
31
Show member pathways
8.6IGF1, TGFB1, TGFB2, TGFB3
32
Show member pathways
8.6IGF1, TGFB1, TGFB2, TGFB3
338.6IGF1, TGFB1, TGFB2, TGFB3
34
Show member pathways
8.6IGF1, TGFB1, TGFB2, TGFB3
35
Show member pathways
8.6IGF1, TGFB1, TGFB2, TGFB3
36
Show member pathways
8.6IGF1, TGFB1, TGFB2, TGFB3
378.6AKR1B1, TGFB1, TGFB2, TGFB3
388.6AKR1B1, TGFB1, TGFB2, TGFB3
39
Show member pathways
8.6NID1, TGFB1, TGFB2, TGFB3
408.3AKR1B1, IGF1, TGFB1, TGFB2, TGFB3

GO Terms for genes affiliated with Keratopathy

About this section

Biological processes related to Keratopathy according to GeneCards Suite gene sharing:

(show all 46)
idNameGO IDScoreTop Affiliating Genes
1cell activationGO:000177510.3IGF1, TGFB1
2regulation of cell migrationGO:003033410.3PAX6, TGFB1
3neuron fate commitmentGO:004866310.2PAX6, TGFB2
4blood vessel developmentGO:000156810.2PAX6, TGFB2
5negative regulation of immune responseGO:005077710.2TGFB1, TGFB2
6pathway-restricted SMAD protein phosphorylationGO:006038910.2TGFB1, TGFB2
7response to laminar fluid shear stressGO:003461610.1TGFB1, TGFB3
8ossification involved in bone remodelingGO:004393210.1TGFB1, TGFB3
9regulation of epithelial to mesenchymal transition involved in endocardial cushion formationGO:190500510.1TGFB1, TGFB3
10frontal suture morphogenesisGO:006036410.1TGFB1, TGFB3
11eye developmentGO:000165410.1PAX6, TGFB2
12positive regulation of collagen biosynthetic processGO:003296710.1TGFB1, TGFB3
13negative regulation of DNA replicationGO:000815610.1TGFB1, TGFB3
14collagen fibril organizationGO:003019910.1CYP1B1, TGFB2
15positive regulation of SMAD protein import into nucleusGO:006039110.0TGFB1, TGFB3
16epithelial to mesenchymal transitionGO:000183710.0TGFB1, TGFB2
17positive regulation of fibroblast proliferationGO:004814610.0IGF1, TGFB1
18SMAD protein signal transductionGO:006039510.0TGFB1, TGFB2
19regulation of gene expressionGO:001046810.0IGF1, PAX6, TGFB1
20positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.9TGFB1, TGFB2
21response to progesteroneGO:00325709.9TGFB1, TGFB3
22positive regulation of cell divisionGO:00517819.9TGFB2, TGFB3
23inner ear developmentGO:00488399.9TGFB1, TGFB3
24mammary gland developmentGO:00308799.9TGFB1, TGFB3
25regulation of multicellular organism growthGO:00400149.7IGF1, MBD5
26negative regulation of epithelial cell proliferationGO:00506809.7TGFB1, TGFB2
27positive regulation of epithelial to mesenchymal transitionGO:00107189.7TGFB1, TGFB3
28response to organic substanceGO:00100339.7IGF1, TGFB1
29negative regulation of macrophage cytokine productionGO:00109369.6TGFB1, TGFB2, TGFB3
30SMAD protein import into nucleusGO:00071849.6TGFB1, TGFB2, TGFB3
31agingGO:00075689.5IGF1, TGFB1, TGFB3
32face morphogenesisGO:00603259.5TGFB1, TGFB2, TGFB3
33female pregnancyGO:00075659.4IGF1, TGFB1, TGFB3
34cell growthGO:00160499.4TGFB1, TGFB2, TGFB3
35growthGO:00400079.3TGFB1, TGFB2, TGFB3
36positive regulation of transcription, DNA-templatedGO:00458939.3IGF1, PAX6, TGFB1, TGFB3
37cell proliferationGO:00082839.2IGF1, TGFB1, TGFB2
38regulation of cell proliferationGO:00421279.1IGF1, TGFB1, TGFB3
39extracellular matrix organizationGO:00301989.1TGFB1, TGFB2, TGFB3
40salivary gland morphogenesisGO:00074359.1PAX6, TGFB1, TGFB2, TGFB3
41positive regulation of protein secretionGO:00507149.1IGF1, TGFB1, TGFB2, TGFB3
42platelet degranulationGO:00025769.0IGF1, TGFB1, TGFB2, TGFB3
43negative regulation of cell proliferationGO:00082859.0CYP1B1, PAX6, TGFB1, TGFB2
44platelet activationGO:00301689.0IGF1, TGFB1, TGFB2, TGFB3
45positive regulation of transcription from RNA polymerase II promoterGO:00459448.9IGF1, PAX6, TGFB1, TGFB3
46transforming growth factor beta receptor signaling pathwayGO:00071798.6TGFB1, TGFB2, TGFB3

Sources for Keratopathy

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet