Aliases & Classifications for Keratopathy

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Aliases & Descriptions for Keratopathy:

Name: Keratopathy 33 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:2283
NCIt43 C27012

Summaries for Keratopathy

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MalaCards based summary: Keratopathy is related to bullous keratopathy and band keratopathy, and has symptoms including corneal structural change, deposit and degeneration, corneal striae and dellen. An important gene associated with Keratopathy is PAX6 (Paired Box 6), and among its related pathways are IL-2 Gene Expression in Activated and Quiescent T-Cells and IL-4 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include endothelial, eye and thyroid, and related mouse phenotypes are hearing/vestibular/ear and craniofacial.

Related Diseases for Keratopathy

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Diseases related to Keratopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 121)
idRelated DiseaseScoreTop Affiliating Genes
1bullous keratopathy12.4
2band keratopathy12.3
3neurotrophic keratopathy12.1
4endotheliitis10.4
5autosomal recessive congenital methemoglobinemia10.3AIRE, NLRP1
6diamond-blackfan anemia10.3TGFB1, TGFB2
7necrotizing ulcerative gingivitis10.3IGF1, PAX6
8keratitis10.2
9strawberry gallbladder10.2TGFB1, TGFB2
10brucella canis brucellosis10.2FBN1, TGFB2
11genetic prion diseases10.2FBN1, TGFB1
12twin-to-twin transfusion syndrome10.2TGFB1, TGFB2
13aniridia10.1
14cataract10.1
15peanut allergy10.1TGFB1, TGFB2
16lagophthalmos10.0
17vitreous abscess10.0TGFB1, TGFB2
18keratoconus10.0
19endothelial dystrophy10.0
20myeloma10.0
21acromicric dysplasia10.0FBN1, TGFB1, TGFB2
22multiple myeloma10.0
23osteopetrosis10.0IGF1, TGFB1
24epidemic typhus10.0FBN1, TGFB1, TGFB2
25corneal intraepithelial dyskeratosis and ectodermal dysplasia10.0
26fuchs' endothelial dystrophy9.9
27herpes zoster9.9
28fibrosclerosis of breast9.9IGF1, TGFB1, TGFB2
29prolactin producing pituitary tumor9.8BMP4, IGF1, TGFB1
30corneal disease9.8
31hypercalcemia9.8
32herpes simplex9.8
33citrullinemia, adult-onset type ii9.8AKR1B1, IGF1, TGFB2
34leprosy9.7
35insulin-like growth factor i9.7
36fabry disease9.7
37arthritis9.7
38crohn's disease9.7
39lymphoma9.7
40ptosis9.7
41xerophthalmia9.7
42cystinosis9.7
43keratomalacia9.7
44corneal neovascularization9.7
45choroiditis9.7
46corneal deposit9.7
47astigmatism9.7
48myopia9.7
49corneal degeneration9.7
50uveitis9.7

Graphical network of the top 20 diseases related to Keratopathy:



Diseases related to keratopathy

Symptoms for Keratopathy

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UMLS symptoms related to Keratopathy:


corneal structural change, deposit and degeneration, corneal striae, dellen, arcus lipoides, corneal leukoma, corneal thickening, corneal flap complication

Drugs & Therapeutics for Keratopathy

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Drugs for Keratopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholinePhase 2, Phase 375251-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
EphedrinePhase 1, Phase 2569299-42-39294
Synonyms:
( )-Pseudoephedrine
(+)-Ephedrin
(+)-Ephedrine
(+)-Pseudoephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(+-)-Ephedrine
(-)-Ephedrine
(-)-Pseudoephedrine
(-)-psi-Ephedrine
(-)-threo-Ephedrine
(1R,2R)-Ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2R)-Ephedrine
(L)-EPHEDRINE
--EPHEDRINE
1-EPHEDRINE
1-Sedrin
134910_ALDRICH
287636_ALDRICH
287644_ALDRICH
299-42-3
304-87-0
30987-59-8
321-96-0
321-97-1
321-98-2
37577-31-4
38732-95-5
45261_FLUKA
4607-45-8
50-98-6
50906-05-3
53214-57-6
649031_ALDRICH
6912-63-6
7009-81-6
90-82-4
968-63-8
AC-20231
AC-20292
AC1L1JGK
AC1L1NUA
AC1L1RFA
AC1L1SR1
AC1L1T31
AC1L1Y3M
AC1O8JUO
AC1Q3XJE
AC1Q3XJM
AC1Q3XJN
AC1Q59F5
AC1Q7701
AI3-02761
AKOS000268842
AR-1A0126
AR-1I7143
Acunaso
Acunaso (TN)
Afrinol
Ambap299-42-3
BIDD:GT0817
BRN 3197916
BRN 4231286
BSPBio_001946
BSPBio_001968
BSPBio_003261
Benylin Decongestant
Besan
Biophedrin
C01575
C02765
C10H15NO
CHEBI:15407
CHEBI:51209
CHEMBL1590
CHEMBL211456
CHEMBL357080
CID11972440
CID5032
CID62946
CID6710657
CID7028
CID8650
CID9294
CID9457
CPD-9954
CPDD 0049
Cenafed
D00124
D08449
DB00852
DB01364
Decofed
DivK1c_000181
DivK1c_000451
DivK1c_000461
Drixoral N.D.
EINECS 202-017-0
EINECS 202-018-6
EINECS 206-080-5
EINECS 206-292-8
EINECS 206-293-3
Eciphin
Efedrin
Efidac/24
Eltor 120
Ephedral
Ephedremal
Ephedrin
Ephedrine
Ephedrine (TN)
Ephedrine (USP)
Ephedrine [USAN:BAN]
Ephedrine l-form
Ephedrital
Ephedrol
Ephedrosan
Ephedrotal
Ephedsol
Ephendronal
Ephoxamin
Fedrin
Genaphed
HSDB 3072
HSDB 3177
I-Sedrin
I01-3584
I01-8925
I01-8928
 
IDI1_000181
IDI1_000451
IDI1_000461
Isoephedrine
Jsp005664
KBio1_000181
KBio1_000451
KBio1_000461
KBio2_001358
KBio2_001500
KBio2_003926
KBio2_004068
KBio2_006494
KBio2_006636
KBio3_001188
KBio3_001446
KBio3_002762
KBioGR_001013
KBioGR_001763
KBioSS_001358
KBioSS_001500
KST-1A9168
Kratedyn
L(+)-psi-Ephedrine
L(-)-Ephedrine
L-(+)-Ephedrine
L-(-)-Ephedrine
L-Ephedrine
L-erythro-2-(Methylamino)-1-phenylpropan-1-ol
L000968
LS-125921
LS-125922
LS-43083
LS-63961
LS-63962
LS-63963
LS-63964
Lexofedrin
Lopac-E-3250
Lopac0_000501
MLS000069657
Manadrin
Mandrin
Maxenal
MolPort-001-684-474
MolPort-001-684-477
MolPort-001-684-478
MolPort-001-684-479
MolPort-001-769-085
Myfedrine
NCGC00015408-01
NCGC00015408-02
NCGC00162174-01
NCGC00178180-01
NCGC00178889-01
NCI-C55652
NCI60_002955
NINDS_000181
NINDS_000451
NINDS_000461
NSC 165609
NSC 170951
NSC 8971
NSC165609
NSC170951
NSC8971
Nasol
Neodurasina
Neodurasina (TN)
Oprea1_287330
PDSP1_000168
PDSP1_001106
PDSP1_001343
PDSP1_001345
PDSP1_001346
PDSP1_001347
PDSP2_000167
PDSP2_001090
PDSP2_001327
PDSP2_001329
PDSP2_001330
PDSP2_001331
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoephedrine (D)
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
Robidrine
SMR000059174
SPBio_000214
SPBio_001365
SPBio_001377
ST023802
STK367993
STOCK1N-42675
Sanedrine
Spectrum2_000137
Spectrum2_001303
Spectrum2_001309
Spectrum3_000414
Spectrum3_000563
Spectrum3_001771
Spectrum4_000497
Spectrum4_001162
Spectrum5_000650
Spectrum5_000879
Spectrum5_001106
Spectrum_000878
Spectrum_001020
Sudafed
Sudafed Decongestant
UNII-03VRY66076
UNII-7CUC9DDI9F
UNII-GN83C131XS
Vencipon
WLN: QYR & Y1 & M1
WLN: QYR&Y1&M1
Zephrol
d-Ephedrine
d-Isoephedrine
d-Pseudoephedrine
d-psi-Ephedrine
l-Ephedrine
l-Pseudoephedrine
racephedrine
trans-Ephedrine
3
PseudoephedrinePhase 1, Phase 256990-82-47028
Synonyms:
( )-Pseudoephedrine
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
(1S,2S)-2-Methylamino-1-phenyl-1-propanol
(1S,2S)-Pseudoephedrine
(1S,2S)-Pseudoephedrine, polymer-bound
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
287636_ALDRICH
304-87-0
30987-59-8
37577-31-4
649031_ALDRICH
90-82-4
AC-20292
AC1L1NUA
Acunaso
Acunaso (TN)
Afrinol
BIDD:GT0817
BRD-K84175871-003-02-2
BSPBio_003261
Balminil Decongestant Syrup
Benylin Decongestant
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alpha-S)- (9CI)
Besan
C02765
C10H15NO
CHEBI:51209
CHEMBL1590
CID7028
CPD-9954
Cenafed
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-Methylamino-1-phenyl-1-propanol
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-Ephedrine
D-Psi-ephedrine
D08449
DB00852
Decofed
Dimetapp Decongestant
Dimetapp Decongestant Pediatric Drops
DivK1c_000451
Drixoral N.D.
Drixoral Nasal Decongestant
EINECS 202-018-6
Efidac 24 Pseudoephedrine Hcl
Efidac/24
Eltor 120
Ephedrine
Genaphed
HSDB 3177
I01-8928
IDI1_000451
 
Isoephedrine
KBio1_000451
KBio2_001358
KBio2_003926
KBio2_006494
KBio3_002762
KBioGR_001763
KBioSS_001358
L(+)-Psi-Ephedrine
L(+)-Psi-ephedrine
L(+)-psi-Ephedrine
L-(+)-Pseudoephedrine
LS-125922
Lopac-E-3250
Maxenal
MolPort-001-684-474
Myfedrine
NCGC00015408-01
NCGC00178180-01
NCI60_002955
NINDS_000451
Neodurasina
Neodurasina (TN)
Novafed
PDSP1_001347
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoefedrina [INN-Spanish]
Pseudoephedrine
Pseudoephedrine (D)
Pseudoephedrine (INN)
Pseudoephedrine D-form
Pseudoephedrine Ephedrine
Pseudoephedrine [INN:BAN]
Pseudoephedrine d-form
Pseudoephedrinum
Pseudoephedrinum [INN-Latin]
Psi-ephedrin
Psi-ephedrine
Robidrine
SPBio_001365
STOCK1N-42675
Spectrum2_001303
Spectrum3_001771
Spectrum4_001162
Spectrum5_000650
Spectrum_000878
Sudafed
Sudafed Decongestant
Sudafed Decongestant 12 Hour
Sudafed Decongestant Extra Strength
Triaminic AM Decongestant Formula
Triaminic Infant Oral Decongestant Drops
UNII-7CUC9DDI9F
alpha-(1-(Methylamino)ethyl)benzyl alcohol
d-Isoephedrine
d-Pseudoephedrine
d-psi-2-Methylamino-1-phenyl-1-propanol
d-psi-Ephedrine
trans-Ephedrine
4
AmbroxolPhase 1, Phase 21418683-91-5
Synonyms:
4-(((2-Amino-3,5-dibromophenyl)methyl)amino)cyclohexanol
4-(2-Amino-3,5-dibromo-benzylamino)-cyclohexanol
4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol
Amboxol
Ambroxol
Ambroxol hcl
Ambroxolum
Bisolvon metabolite vIII
 
Bromhexine metabolite vIII
Bromhexine-metabolite vIII
N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol
N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol
Tabcin
Tabcin (TN)
trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol
trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol
5PREDNISOLONE ACETATEPhase 21118
6
BevacizumabPhase 21938216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
7
PrednisolonePhase 2111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
8glucocorticoidsPhase 24756
9
FluorometholonePhase 218426-13-19878
Synonyms:
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11beta,17alpha-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
426-13-1
9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
AC-3520
AC1L1U0Y
AI3-52813
Alcon Brand of Fluorometholone
Allergan Brand 1 of Fluorometholone
Allergan Brand 2 of Fluorometholone
Allergan Brand 3 of Fluorometholone
BPBio1_001029
BRD-K64862097-001-03-9
BSPBio_000935
CHEMBL1200600
CID9878
Cortilet
Cortisdin
D005469
D01367
DB00324
Delmeson
EINECS 207-041-5
Efflumidex
F0414
F9381_SIGMA
FML
FML Forte
FML Liquifilm
FML S.O.P
FML-S Liquifilm
Fluaton
Flucon
Flucon, Isopto
Flumetholon
Fluor Op
Fluor-OP
Fluor-Op
Fluor-op (TN)
Fluormetholon
Fluormetholone
Fluormetholonum
Fluoro Ophtal
Fluoro-Ophtal
Fluoromethalone
Fluorometholon
Fluorometholone
 
Fluorometholone (JP15/USP/INN)
Fluorometholone [INN:BAN:JAN]
Fluorometholonum
Fluorometholonum [INN-Latin]
Fluorometolona
Fluorometolona [INN-Spanish]
Fluorometolone
Fluorometolone [DCIT]
Fluorométholone
Fluoropos
Fml (TN)
HMS1570O17
Isdin Brand of Fluorometholone
Isopto Flucon
LS-118455
Loticort
MLS000069537
MLS001076157
MolPort-003-941-413
NCGC00021575-03
NCI60_002886
NSC 33001
NSC-33001
NSC33001
Neo-Oxylone
Novartis Brand of Fluorometholone
Oxylone
Oxylone (TN)
PMS Fluorometholone
PMS-Fluorometholone
Pharm Allergan Brand of Fluorometholone
Pharm-Allergan Brand of Fluorometholone
Pharmascience Brand of Fluorometholone
Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl- (8CI)
Prestwick0_000718
Prestwick1_000718
Prestwick2_000718
Prestwick3_000718
Prestwick_227
SMR000058598
SPBio_002856
Trilcin
U 8614
UNII-SV0CSG527L
Ursapharm Brand of Fluorometholone
Ursnon
Winzer Brand of Fluorometholone
ZINC03876158
component of Neo-Oxylone
fluorometholone
10
MethylprednisolonePhase 2111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
11tafenoquinePhase 114
12cadexomer iodine484
13
Iodine5167553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
14Alkylating Agents4573
15
Miconazole357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
16
Lidocaine1168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
17
Povidone-iodine14425655-41-8
Synonyms:
 
Betadine
18
Folic AcidNutraceutical414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
19FolateNutraceutical4143
20
RiboflavinNutraceutical15883-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2

Interventional clinical trials:

(show all 34)
idNameStatusNCT IDPhase
1Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision LensesCompletedNCT01268306Phase 4
2Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic KeratopathyRecruitingNCT02600429Phase 3
3Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye DiseaseRecruitingNCT00370734Phase 2, Phase 3
4Amniotic Membrane Graft In Syntomathic Bullous KeratopathyCompletedNCT01926535Phase 2
5Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)CompletedNCT01448213Phase 2
6Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal HealingCompletedNCT02746848Phase 1, Phase 2
7Effects of Oral Mucolytics on Tear Film and Ocular SurfaceCompletedNCT01713179Phase 1, Phase 2
8Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)RecruitingNCT01808378Phase 2
9Study of Ataluren in Patients With AniridiaRecruitingNCT02647359Phase 2
10Bevacizumab for the Treatment of Corneal NeovascularizationActive, not recruitingNCT00992849Phase 2
11Pain and Visual Outcome in Intravitreal Bevacizumab InjectionEnrolling by invitationNCT02790775Phase 2
12A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-Host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) PatientsTerminatedNCT01972438Phase 2
13A Study of SAR428926 in Patients With Advanced Solid TumorsRecruitingNCT02575781Phase 1
14Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)RecruitingNCT02658435Phase 1
15Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous KeratopathyCompletedNCT00659308
16The Effects of Riboflavin/ Ultraviolet-A Corneal Cross-linking on the Signs and Symptoms of Bullous KeratopathyCompletedNCT01106274
17Automated Lamellar Keratectomy in Symptomatic Patients With Bullous KeratopathyCompletedNCT00654888
18Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal NeovasculizationCompletedNCT00681603
19The SNEC DSAEK EndoGlide Clinical TrialCompletedNCT01122043
20A Comparison of Hydrogel Dressings and Ocular Lubricants in the Prevention on Corneal Damage in the Critically IllCompletedNCT00513734
21Comparison of Patient Comfort After Two Anesthetic Protocols for Injections Into the EyeCompletedNCT01087489
22Eyelash Line Resection for Entropion Associated With Down's SyndromeCompletedNCT01758718
23Correlation of Gene Abnormalities and Clinical Manifestations of AniridiaCompletedNCT00265590
24Long-term Topical Cyclosporine for Atopic KeratoconjunctivitisCompletedNCT00987467
25Staged and Combined Surgery for Cataract Patients With Corneal Endothelial DysfunctionRecruitingNCT02523950
26Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)RecruitingNCT02020044
27Study of Endothelial Keratoplasty OutcomesRecruitingNCT00800111
28Comparing Endoglide to Endoserter for DSAEK Graft InsertionRecruitingNCT01791075
29Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal EdemaRecruitingNCT02660151
30Corneal Transplantation Guided by OCT RESCANNot yet recruitingNCT02736877
31Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture MediaNot yet recruitingNCT00623584
32Comparison of Aqueous and Plasma Glucose Level in Diabetic PatientsNot yet recruitingNCT02750098
33Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal EdemaNot yet recruitingNCT01890252
34Topical Steroid Treatment After Posterior Lamellar Corneal TransplantationWithdrawnNCT01682421

Search NIH Clinical Center for Keratopathy

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Keratopathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Keratopathy:
Adipose-derived stem cells for treatment of bilateral limbic-associated keratopathy
Embryonic/Adult Cultured Cells Related to Keratopathy:
Adipose-derived stem cells

Genetic Tests for Keratopathy

About this section

Anatomical Context for Keratopathy

About this section

MalaCards organs/tissues related to Keratopathy:

34
Endothelial, Eye, Thyroid, T cells, B cells, Myeloid, Skin

Animal Models for Keratopathy or affiliated genes

About this section

MGI Mouse Phenotypes related to Keratopathy:

39 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.4BMP4, IGF1, PAX6, TGFB2, TNC
2MP:00053828.3BMP4, FBN1, PAX6, TGFB1, TGFB2
3MP:00053897.6AIRE, BMP4, FBN1, IGF1, PAX6, TGFB1
4MP:00053887.6AIRE, BMP4, FBN1, IGF1, PAX6, TGFB1
5MP:00053697.5BMP4, FBN1, IGF1, NID1, PAX6, TGFB1
6MP:00053797.3AIRE, BMP4, FBN1, IGF1, PAX6, TGFB1
7MP:00053857.3BMP4, FBN1, IGF1, NID1, PAX6, TGFB1
8MP:00053847.2AIRE, BMP4, FBN1, IGF1, NID1, PAX6
9MP:00053677.2AKR1B1, BMP4, FBN1, IGF1, PAX6, TGFB1
10MP:00053907.2AKR1B1, BMP4, FBN1, IGF1, PAX6, TGFB1
11MP:00053917.1AIRE, AKR1B1, BMP4, KRT12, NID1, PAX6
12MP:00053866.8AIRE, AKR1B1, BMP4, FBN1, NID1, PAX6
13MP:00036316.5AIRE, BMP4, FBN1, IGF1, NID1, PAX6
14MP:00053765.6AIRE, AKR1B1, BMP4, FBN1, IGF1, NLRP1

Publications for Keratopathy

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Articles related to Keratopathy:

(show top 50)    (show all 716)
idTitleAuthorsYear
1
Risk of Band Keratopathy in Patients with End-Stage Renal Disease. (27346848)
2016
2
Idiopathic stromal keratitis resembling central toxic keratopathy. (26210054)
2015
3
Real-Time Microscope-Integrated OCT to Improve Visualization in DSAEK for Advanced Bullous Keratopathy. (26509766)
2015
4
Stem cell therapies in the treatment of diabetic retinopathy and keratopathy. (26454200)
2015
5
A simple technique for temporary eyelid closure in severe exposure keratopathy. (25448147)
2014
6
Midinfrared Laser Pancorneal Coagulation as a Method of Treatment for Painful Bullous Keratopathy. (23974894)
2013
7
Treatment of bullous keratopathy with corneal collagen cross-linking in two dogs. (24373539)
2013
8
New findings for an old disease: morphological studies on pseudoexfoliation syndrome-related keratopathy and binocular asymmetry. (24104940)
2013
9
Prevalence of linear keratopathy in a herd of Lipizzaners over an 18-month period. (23839726)
2013
10
Central toxic keratopathy: a clinical case series. (23536420)
2013
11
Characteristics of, prevalence of, and risk factors for corneal pigmentation (pigmentary keratopathy) in Pugs. (23971846)
2013
12
Tropheryma whipplei Crystalline Keratopathy: Report of a Case and Updated Review of the Literature. (22988534)
2012
13
Chloroquine keratopathy of rheumatoid arthritis patients detected by in vivo confocal microscopy. (22440160)
2012
14
Long-term outcome of central toxic keratopathy after photorefractive keratectomy. (21926568)
2011
15
Reproducibility of cornea measurements in anterior segment OCT images of normal eyes and eyes with bullous keratopathy analyzed with the Zhongshan Assessment Program. (21828152)
2011
16
Confocal laser-scanning microscopy allows differentiation between Fabry disease and amiodarone-induced keratopathy. (21720814)
2011
17
Corneal nerve aberrations in bullous keratopathy. (21310389)
2011
18
Topical anesthetic abuse keratopathy: a commonly overlooked health care problem. (21598429)
2011
19
Penetrating keratoplasty for bullous keratopathy after trabeculectomy. (18369373)
2009
20
Corneal collagen cross-linking in bullous keratopathy. (19714792)
2009
21
Nummular keratopathy in a patient with Hyper-IgD Syndrome. (19656398)
2009
22
Amiodarone-induced keratopathy: full-thickness corneal involvement. (18327053)
2008
23
Neuroparalytic keratopathy as the first sign of a cerebral meningioma. (17894293)
2007
24
Anaesthetic abuse keratopathy as a manifestation of ocular Munchausen's syndrome. (16451265)
2006
25
In vivo confocal microscopy in congenital rubella keratopathy. (15803165)
2006
26
Hypopyon uveitis following band keratopathy removal in ankylosing spondylitis-a case report. (16507493)
2006
27
Confocal microscopy of Thygeson's superficial punctate keratopathy. (15670099)
2005
28
The implications of the upregulation of ICAM-1/VCAM-1 expression of corneal fibroblasts on the pathogenesis of allergic keratopathy. (16303942)
2005
29
Management of aniridic keratopathy with keratolimbal allograft: a limbal stem cell transplantation technique. (12511357)
2003
30
Long-term follow-up for bullous keratopathy after sato-type anterior-posterior corneal refractive surgery. (14644229)
2003
31
Biofilm formation and coccal organisms in infectious crystalline keratopathy. (11913899)
2002
32
In vivo confocal microscopy of patients with amiodarone-induced keratopathy. (11333323)
2001
33
Infectious crystalline keratopathy. (10656309)
2000
34
Infectious keratitis in climatic droplet keratopathy. (10928756)
2000
35
Nd:YAG laser corneal disruption as adjuvant treatment for infectious crystalline keratopathy. (10926992)
2000
36
Infectious crystalline keratopathy: a case report. (9810093)
1998
37
The current situation of lagophthalmos and keratopathy of leprosy in PR China. (9598407)
1998
38
Association of tear lipid layer interference patterns with superficial punctate keratopathy. (9634902)
1998
39
Neurotrophic and anhidrotic keratopathy treated with substance P and insulinlike growth factor 1. (9230840)
1997
40
Vortex keratopathy associated with atovaquone. (7485371)
1995
41
Detection of mRNA for the cytokines, interleukin-1 alpha and interleukin-8, in corneas from patients with pseudophakic bullous keratopathy. (7657553)
1995
42
Pseudophakic bullous keratopathy and intraocular lens fixation. To suture or not: that is the question! (7945030)
1994
43
Treatment of calcific band keratopathy by Nd:YAG laser. (1638162)
1992
44
Climatic droplet keratopathy, exfoliation syndrome, and cataract. (1768663)
1991
45
The dilemma of pseudophakic bullous keratopathy. (2674810)
1989
46
The bandage lens in bullous keratopathy. (2594381)
1989
47
Pseudophakic bullous keratopathy: relationship with endothelial cell density and use of a predictive cell loss model. A preliminary report. (3720342)
1986
48
Intraocular lens replacement in pseudophakic bullous keratopathy. (3901432)
1985
49
Band keratopathy in hypercalcemia of myeloma. (7074461)
1982
50
Bullous keratopathy (Fuchs' endothelial dystrophy) treated systemically with 4-trans-amino-cyclohexano-carboxylic acid. (302548)
1977

Variations for Keratopathy

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Expression for genes affiliated with Keratopathy

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Search GEO for disease gene expression data for Keratopathy.

Pathways for genes affiliated with Keratopathy

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Pathways related to Keratopathy according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.4TGFB1, TGFB2
29.4TGFB1, TGFB2
39.4TGFB1, TGFB2
4
Show member pathways
9.2NID1, TGFB1, TNC
59.1IGF1, TGFB1, TGFB2
6
Show member pathways
9.1IGF1, TGFB1, TGFB2
79.1IGF1, TGFB1, TGFB2
89.1BMP4, IGF1, PAX6
99.1BMP4, IGF1, PAX6
108.9BMP4, IGF1, TGFB1
11
Show member pathways
8.9TGFB1, TGFB2, TNC
128.9TGFB1, TGFB2, TNC
138.7BMP4, IGF1, PAX6, TGFB1
148.7BMP4, IGF1, PAX6, TGFB1
158.6BMP4, TGFB1, TGFB2
168.6BMP4, TGFB1, TGFB2
178.6BMP4, TGFB1, TGFB2
18
Show member pathways
8.6BMP4, TGFB1, TGFB2
19
Show member pathways
8.6BMP4, TGFB1, TGFB2
208.3BMP4, IGF1, TGFB1, TGFB2
218.3BMP4, IGF1, TGFB1, TGFB2
22
Show member pathways
8.3BMP4, IGF1, TGFB1, TGFB2
238.3BMP4, IGF1, TGFB1, TGFB2
24
Show member pathways
8.3BMP4, IGF1, TGFB1, TGFB2
25
Show member pathways
8.1BMP4, FBN1, TGFB1, TGFB2
26
Show member pathways
7.3BMP4, FBN1, IGF1, TGFB1, TGFB2, TNC
27
Show member pathways
7.2BMP4, FBN1, NID1, TGFB1, TGFB2, TNC

GO Terms for genes affiliated with Keratopathy

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Cellular components related to Keratopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interstitial matrixGO:000561410.3IGF1, TNC
2platelet alpha granule lumenGO:00310939.8IGF1, TGFB1, TGFB2
3basement membraneGO:00056049.6FBN1, NID1, TNC
4neuronal cell bodyGO:00430258.7IGF1, NLRP1, TGFB1, TGFB2
5extracellular matrixGO:00310128.3FBN1, NID1, TGFB1, TGFB2, TNC
6proteinaceous extracellular matrixGO:00055788.1BMP4, FBN1, NID1, TGFB1, TNC
7extracellular regionGO:00055766.9BMP4, FBN1, IGF1, NID1, TGFB1, TGFB2
8extracellular spaceGO:00056156.8AKR1B1, BMP4, FBN1, IGF1, TGFB1, TGFB2

Biological processes related to Keratopathy according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription regulatory region DNA bindingGO:200067910.5IGF1, TGFB1
2cell activationGO:000177510.3IGF1, TGFB1
3SMAD protein import into nucleusGO:000718410.1TGFB1, TGFB2
4pathway-restricted SMAD protein phosphorylationGO:006038910.1TGFB1, TGFB2
5positive regulation of protein localization to nucleusGO:190018210.1TGFB1, TGFB2
6cellular response to insulin-like growth factor stimulusGO:199031410.1FBN1, TGFB1
7telencephalon regionalizationGO:002197810.1BMP4, PAX6
8negative regulation of macrophage cytokine productionGO:001093610.0TGFB1, TGFB2
9negative regulation of immune responseGO:005077710.0TGFB1, TGFB2
10cell-cell junction organizationGO:004521610.0TGFB1, TGFB2
11pituitary gland developmentGO:002198310.0BMP4, PAX6
12common-partner SMAD protein phosphorylationGO:00071829.9BMP4, TGFB1
13regulation of cartilage developmentGO:00610359.9BMP4, TGFB1
14regulation of protein import into nucleusGO:00423069.9BMP4, TGFB1
15positive regulation of pri-miRNA transcription from RNA polymerase II promoterGO:19028959.9BMP4, TGFB1
16salivary gland morphogenesisGO:00074359.8PAX6, TGFB1, TGFB2
17face morphogenesisGO:00603259.8TGFB1, TGFB2
18positive regulation of collagen biosynthetic processGO:00329679.8BMP4, TGFB1
19positive regulation of SMAD protein import into nucleusGO:00603919.8BMP4, TGFB1
20membranous septum morphogenesisGO:00031499.7BMP4, TGFB2
21pulmonary valve morphogenesisGO:00031849.7BMP4, TGFB2
22negative regulation of myoblast differentiationGO:00456629.7BMP4, TGFB1
23cardiac right ventricle morphogenesisGO:00032159.7BMP4, TGFB2
24outflow tract septum morphogenesisGO:00031489.7BMP4, TGFB2
25pharyngeal arch artery morphogenesisGO:00616269.7BMP4, TGFB2
26positive regulation of ossificationGO:00457789.7BMP4, TGFB2
27platelet degranulationGO:00025769.7IGF1, TGFB1, TGFB2
28odontogenesisGO:00424769.6BMP4, TGFB2
29positive regulation of smooth muscle cell proliferationGO:00486619.6AKR1B1, BMP4, IGF1
30positive regulation of protein secretionGO:00507149.5IGF1, TGFB1, TGFB2
31neuron fate commitmentGO:00486639.4BMP4, PAX6, TGFB2
32camera-type eye developmentGO:00430109.4BMP4, FBN1, PAX6
33positive regulation of epithelial cell proliferationGO:00506799.3BMP4, IGF1, TGFB1
34SMAD protein signal transductionGO:00603959.3BMP4, TGFB1, TGFB2
35response to woundingGO:00096119.2PAX6, TGFB1, TGFB2, TNC
36blood vessel developmentGO:00015689.2BMP4, PAX6, TGFB2
37positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.2BMP4, TGFB1, TGFB2
38response to hypoxiaGO:00016669.1IGF1, TGFB1, TGFB2
39positive regulation of cell migrationGO:00303359.1BMP4, IGF1, TGFB1
40negative regulation of gene expressionGO:00106299.1BMP4, TGFB1, TGFB2
41regulation of gene expressionGO:00104689.0BMP4, IGF1, PAX6, TGFB1
42negative regulation of epithelial cell proliferationGO:00506808.8BMP4, PAX6, TGFB1, TGFB2
43extracellular matrix organizationGO:00301988.8FBN1, NID1, TGFB2, TNC
44positive regulation of transcription, DNA-templatedGO:00458938.7AIRE, BMP4, IGF1, PAX6, TGFB1
45skeletal system developmentGO:00015018.6BMP4, FBN1, IGF1, TGFB2
46negative regulation of cell proliferationGO:00082858.5BMP4, PAX6, TGFB1, TGFB2
47wound healingGO:00420608.1BMP4, TGFB1, TGFB2, TNC
48positive regulation of gene expressionGO:00106288.1BMP4, PAX6, TGFB1, TGFB2, TNC
49positive regulation of transcription from RNA polymerase II promoterGO:00459448.1AIRE, BMP4, IGF1, PAX6, TGFB1
50positive regulation of cell proliferationGO:00082847.7BMP4, IGF1, TGFB1, TGFB2, TNC

Molecular functions related to Keratopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1type III transforming growth factor beta receptor bindingGO:003471410.0TGFB1, TGFB2
2type II transforming growth factor beta receptor bindingGO:00051149.9TGFB1, TGFB2
3transforming growth factor beta receptor bindingGO:00051609.0BMP4, TGFB1, TGFB2
4cytokine activityGO:00051258.3BMP4, TGFB1, TGFB2
5growth factor activityGO:00080838.3BMP4, IGF1, TGFB1, TGFB2

Sources for Keratopathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet