Aliases & Classifications for Keratosis

Aliases & Descriptions for Keratosis:

Name: Keratosis 12 42 14 69
Actinic Keratosis 69
Hyperkeratosis 69

Classifications:



External Ids:

Disease Ontology 12 DOID:161
MeSH 42 D007642
NCIt 47 C34747
SNOMED-CT 64 254666005
UMLS 69 C0022593

Summaries for Keratosis

Disease Ontology : 12 A skin disease characterized_by growth of keratin on the skin or mucous membranes.

MalaCards based summary : Keratosis, also known as actinic keratosis, is related to palmoplantar keratosis and keratosis palmoplantaris striata iii, and has symptoms including exanthema, pruritus and trichorrhexis invaginata. An important gene associated with Keratosis is MBTPS2 (Membrane Bound Transcription Factor Peptidase, Site 2), and among its related pathways/superpathways are Developmental Biology and Pathways in cancer. The drugs Aminolevulinic acid and Imiquimod have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and breast, and related phenotypes are cellular and growth/size/body region

Wikipedia : 71 Keratosis (from keratinocyte, the prominent cell type in the epidermis, and -osis, abnormal) is a growth... more...

Related Diseases for Keratosis

Diseases related to Keratosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 229)
id Related Disease Score Top Affiliating Genes
1 palmoplantar keratosis 33.5 CDKN2A LRP1 TP53
2 keratosis palmoplantaris striata iii 33.0 CTSC KRT10 KRT9
3 folliculitis 30.0 FGFR3 PIK3CA
4 cryoglobulinemia 29.6 CDKN2A FGFR3 TP53
5 actinic keratosis 12.4
6 keratosis, seborrheic, somatic 12.2
7 keratosis pilaris 12.2
8 keratosis follicularis spinulosa decalvans 12.2
9 inverted follicular keratosis 12.1
10 keratosis linearis with ichthyosis congenita and sclerosing keratoderma 12.1
11 keratosis follicularis spinulosa decalvans, x-linked 12.0
12 keratosis palmoplantaris striata i, ad 12.0
13 vulvar seborrheic keratosis 11.9
14 keratosis palmoplantaris striata 11.9
15 inflamed seborrheic keratosis 11.9
16 keratosis palmoplantaris striata ii 11.8
17 keratosis follicularis, dwarfism, and cerebral atrophy 11.8
18 darier disease 11.7
19 keratosis palmaris et plantaris with clinodactyly 11.7
20 keratosis palmoplantaris adenocarcinoma of the colon 11.6
21 keratosis, focal palmoplantar and gingival 11.6
22 circumscribed disseminated keratosis jadassohn lew type 11.6
23 vulvar inverted follicular keratosis 11.6
24 papillon-lefevre syndrome 11.5
25 meleda disease 11.5
26 keratoderma, palmoplantar, punctate type ia 11.5
27 tyrosinemia, type ii 11.4
28 haim-munk syndrome 11.4
29 focal palmoplantar and gingival keratoderma 11.4
30 punctate palmoplantar keratoderma 11.3
31 cholesteatoma 11.0
32 melanoacanthoma 11.0
33 clear cell acanthoma 11.0
34 ichthyosis vulgaris 11.0
35 tylosis with esophageal cancer 11.0
36 palmoplantar keratoderma, epidermolytic 11.0
37 cole disease 11.0
38 naxos disease 10.9
39 erythrokeratodermia variabilis et progressiva 10.9
40 actinic cheilitis 10.8
41 palmoplantar keratoderma, nagashima type 10.8
42 palmoplantar keratoderma, nonepidermolytic 10.8
43 schopf-schulz-passarge syndrome 10.8
44 keratoderma palmoplantaris transgrediens 10.8
45 burnett schwartz berberian syndrome 10.8
46 olmsted syndrome, x-linked 10.7
47 peeling skin with leukonychia, acral punctate keratoses, cheilitis, and knuckle pads 10.7
48 mucoepithelial dysplasia, hereditary 10.7
49 hereditary papulotranslucent acrokeratoderma 10.7
50 white sponge nevus 1 10.6

Comorbidity relations with Keratosis via Phenotypic Disease Network (PDN):


Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Keratosis, Seborrheic, Somatic

Graphical network of the top 20 diseases related to Keratosis:



Diseases related to Keratosis

Symptoms & Phenotypes for Keratosis

UMLS symptoms related to Keratosis:


exanthema, pruritus, trichorrhexis invaginata

MGI Mouse Phenotypes related to Keratosis:

44 (show all 16)
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.36 FGFR3 GJA1 GJB2 KRT17 LRP1 MCM2
2 growth/size/body region MP:0005378 10.36 ATP2A2 CDKN2A CTSC FGFR3 GJA1 GJB2
3 homeostasis/metabolism MP:0005376 10.27 ATP2A2 CDKN2A CTSC FGFR3 GJA1 GJB2
4 immune system MP:0005387 10.22 ATP2A2 CDKN2A CTSC FGFR3 GJA1 GJB2
5 integument MP:0010771 10.2 ATP2A2 CDKN2A CTSC FGFR3 GJA1 GJB2
6 embryo MP:0005380 10.13 ATP2A2 CDKN2A GJA1 GJB2 LRP1 MCM2
7 nervous system MP:0003631 10.11 ATP2A2 CDKN2A CTSC FGFR3 GJA1 GJB2
8 digestive/alimentary MP:0005381 10.08 ATP2A2 CDKN2A FGFR3 KRT17 MCM2 SLURP1
9 adipose tissue MP:0005375 10.03 LRP1 MCM2 PIK3CA SAT1 SLURP1 TP53
10 muscle MP:0005369 10.03 ATP2A2 CDKN2A GJA1 LRP1 MCM2 MMP2
11 neoplasm MP:0002006 10.01 ATP2A2 CDKN2A FGFR3 MCM2 MMP2 PIK3CA
12 normal MP:0002873 9.91 CTSC FGFR3 GJA1 GJB2 LRP1 MCM2
13 no phenotypic analysis MP:0003012 9.87 CDKN2A FGFR3 GJA1 GJB2 KRT17 PIK3CA
14 reproductive system MP:0005389 9.81 GJA1 GJB2 LRP1 PIK3CA SAT1 TP53
15 respiratory system MP:0005388 9.56 ATP2A2 CDKN2A FGFR3 GJA1 MCM2 MMP2
16 skeleton MP:0005390 9.28 ATP2A2 CDKN2A FGFR3 GJA1 GJB2 LRP1

Drugs & Therapeutics for Keratosis

Drugs for Keratosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 204)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aminolevulinic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 106-60-5 137
2
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
3
Fluorouracil Approved Phase 4,Phase 3,Early Phase 1 51-21-8 3385
4
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 1 15307-86-5 3033
5
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
6
Ethanol Approved Phase 4,Phase 2 64-17-5 702
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
8
Bezafibrate Approved Phase 4 41859-67-0 39042
9
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
10
Salicylic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 69-72-7 338
11
Tacrolimus Approved, Investigational Phase 4,Phase 1,Phase 2 104987-11-3 445643 439492
12
Menthol Approved Phase 4 2216-51-5 16666
13
Everolimus Approved Phase 4,Phase 1,Phase 2 159351-69-6 6442177
14
Sirolimus Approved, Investigational Phase 4,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
15
Azathioprine Approved Phase 4 446-86-6 2265
16
Cyclosporine Approved, Investigational, Vet_approved Phase 4 79217-60-0, 59865-13-3 5284373 6435893
17
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
18
Mycophenolic acid Approved Phase 4 24280-93-1 446541
19
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 11103-57-4, 68-26-8 445354
20
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 6221 10883523 5280795
21
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1 50-14-6 5280793
22 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1
23 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
24 Interferon Inducers Phase 4,Phase 3,Phase 2,Phase 1
25 interferons Phase 4,Phase 3,Phase 2,Phase 1
26 Methyl 5-aminolevulinate Phase 4,Phase 3,Phase 2,Phase 1
27 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
28 Photosensitizing Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
29 Protective Agents Phase 4,Phase 3,Phase 2
30 Radiation-Protective Agents Phase 4,Phase 2
31 Sunscreening Agents Phase 4,Phase 3,Phase 2
32 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
33 Antimetabolites Phase 4,Phase 3,Phase 2,Early Phase 1
34 Antimetabolites, Antineoplastic Phase 4,Phase 3,Early Phase 1
35 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Hormone Antagonists Phase 4,Phase 2,Phase 3
37 Hormones Phase 4,Phase 2,Phase 3
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
39 Anticholesteremic Agents Phase 4,Phase 2
40 Hypolipidemic Agents Phase 4,Phase 2
41 Lipid Regulating Agents Phase 4,Phase 2
42 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
43 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
44 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1
46 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
48 Retinol palmitate Phase 4,Phase 3,Phase 2
49
Alginic acid Phase 4 9005-32-7
50 Mineral Oil Phase 4

Interventional clinical trials:

(show top 50) (show all 329)
id Name Status NCT ID Phase
1 Imiquimod Versus Photodynamic Therapy of Actinic Keratoses in Organ Transplant Recipients Unknown status NCT01538901 Phase 4
2 Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses Unknown status NCT01229319 Phase 4
3 Long Term Efficacy and Safety of Eryfotona AK-NMSC® in Patients With Actinic Keratosis Unknown status NCT01656226 Phase 4
4 Potential Effect of Topical Imiquimod on Atrial Ectopy in Patients With Actinic Keratosis Unknown status NCT01413763 Phase 4
5 Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015% Completed NCT02446223 Phase 4
6 Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis Completed NCT00116649 Phase 4
7 Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses Completed NCT00774787 Phase 4
8 Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis Completed NCT02716714 Phase 4
9 Study of Imiquimod 5% Cream in Addition to Cryotherapy in the Management of Actinic Keratoses Completed NCT00110682 Phase 4
10 Study to Assess the Safety and Efficacy of Imiquimod 5% Cream for the Treatment of Actinic Keratosis on the Arms and Hands Completed NCT00115154 Phase 4
11 Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT) Completed NCT01000636 Phase 4
12 Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses Completed NCT00777127 Phase 4
13 Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2) Completed NCT01453179 Phase 4
14 An Open-Label 18-Month Safety Study of Fluorouracil Cream 0.5% for the Treatment of Actinic Keratoses Completed NCT00377273 Phase 4
15 Comparison of the Efficacy and Tolerability of Solaraze for 3 Versus 6 Months in Patients With Mild to Moderate Actinic Keratosis Located on the Face and Head Completed NCT00204542 Phase 4
16 Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy Completed NCT00695578 Phase 4
17 Safety and Efficacy of Ingenol Mebutate 0.05% Gel When Used After Cryotherapy in the Hypertrophic Actinic Keratoses Completed NCT02251652 Phase 4
18 Effects of Topical Diclofenac on Tumor Metabolism Completed NCT01935531 Phase 4
19 Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp Completed NCT02406014 Phase 4
20 Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population Completed NCT00696488 Phase 4
21 Daylight-PDT for AKs: Comparing Two Photosensitizers (BF-200 ALA and MAL) Completed NCT01893203 Phase 4
22 Zurich Multiple Endpoint Vitamin D Trial in Knee OA Patients Completed NCT00599807 Phase 4
23 Comparison of Efficacy of Intralesional Triamcinolone Injection and Clobetasol Propionate Ointment for Psoriatic Nails Completed NCT01703325 Phase 4
24 The Effect of Fibrate Therapy in Two Patients With Neutral Lipid Storage Disease With Myopathy (NLSDM) Completed NCT01527318 Phase 4
25 Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA Gel Recruiting NCT02647151 Phase 4
26 IM Versus 5-FU Versus IMI Versus MAL-PDT in Treatment of Actinic Keratosis Recruiting NCT02281682 Phase 4
27 Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients Recruiting NCT02866695 Phase 4
28 Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL) Active, not recruiting NCT02464709 Phase 4
29 Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times Active, not recruiting NCT02622594 Phase 4
30 Daylight-PDT With MAL for AK and Photodamaged Skin Active, not recruiting NCT02736760 Phase 4
31 Risk of Squamous Cell Carcinoma on Skin Areas Treated With Ingenol Mebutate Gel, 0.015% and Imiquimod Cream, 5% Active, not recruiting NCT01926496 Phase 4
32 Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy Not yet recruiting NCT02990221 Phase 4
33 Menthol for PDT Pain Not yet recruiting NCT02984072 Phase 4
34 Treatment of Actinic Keratoses of the Face With Imiquimod 3.75% Cream Followed by Photodynamic Therapy Terminated NCT01203878 Phase 4
35 Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study Terminated NCT00944216 Phase 4
36 Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol Terminated NCT00866684 Phase 4
37 Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol Terminated NCT01797315 Phase 4
38 T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum Unknown status NCT00002811 Phase 3
39 5fluorouracil for Advanced Photoaging Unknown status NCT01405144 Phase 3
40 A Study of the Clinicopathologic Behaviour of the Different Types of Unsafe Chronic Otitis Media Unknown status NCT00270660 Phase 3
41 Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine Cutaneous Unknown status NCT01222000 Phase 3
42 A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations Completed NCT00742391 Phase 3
43 A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations Completed NCT00942604 Phase 3
44 Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment Completed NCT01459393 Phase 3
45 A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) Completed NCT00915551 Phase 3
46 A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) Completed NCT00916006 Phase 3
47 Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp Completed NCT00304239 Phase 3
48 Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp Completed NCT00306800 Phase 3
49 Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic Keratoses Completed NCT02289768 Phase 3
50 Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities Completed NCT02137785 Phase 3

Search NIH Clinical Center for Keratosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: keratosis

Genetic Tests for Keratosis

Anatomical Context for Keratosis

MalaCards organs/tissues related to Keratosis:

39
Skin, T Cells, Breast, Testes, Liver, Kidney, Colon

Publications for Keratosis

Articles related to Keratosis:

(show top 50) (show all 1122)
id Title Authors Year
1
CD40 Ligand Is Increased in Mast Cells in Psoriasis and Actinic Keratosis but Less So in Epithelial Skin Carcinomas. ( 28267402 )
2017
2
Predictors of actinic keratosis count in patients with multiple keratinocyte carcinomas: A cross-sectional study. ( 28088997 )
2017
3
A seamless Phase I/II dose-finding trial assessing ingenol disoxate (LEO 43204) for field treatment of actinic keratosis on the scalp. ( 28078678 )
2017
4
Pharmacoeconomic Considerations in Treating Actinic Keratosis: An Update. ( 27785771 )
2017
5
Acantholytic squamous cell carcinoma is usually associated with hair follicles, not acantholytic actinic keratosis, and is not "high risk": Diagnosis, management, and clinical outcomes in a series of 115 cases. ( 27889291 )
2017
6
Photodynamic Therapy Effective for the Treatment of Actinic Keratosis and Basal Cell Carcinoma in Bullous Pemphigoid Patients. ( 28373119 )
2017
7
Nagashima-type palmoplantar keratosis in a Chinese Han population. ( 27666198 )
2016
8
Differentiating Regressed Melanoma from Regressed Lichenoid Keratosis. ( 28026045 )
2016
9
Photodynamic therapy in the management of actinic keratosis: Retrospective evaluation of outcome. ( 27174210 )
2016
10
Nodulocystic Basal Cell Carcinoma Arising Directly from a Seborrheic Keratosis: A Rare Case Report. ( 27512194 )
2016
11
Pain evaluation in patients affected by cutaneous squamous cell carcinoma and actinic keratosis: an observational study. ( 27096539 )
2016
12
Italian expert consensus for the management of actinic keratosis in immunocompetent patients. ( 27060910 )
2016
13
PDT and emerging therapies for Actinic Keratosis-A resource letter. ( 27613999 )
2016
14
Long-term use of a new topical formulation containing piroxicam 0.8% and sunscreen: efficacy and tolerability on actinic keratosis. A proof of concept study. ( 27046744 )
2016
15
Adherence to topical therapies in actinic keratosis: A literature review. ( 27161045 )
2016
16
Fractional Carbon Dioxide Laser for Keratosis Pilaris: A Single-Blind, Randomized, Comparative Study. ( 27247936 )
2016
17
Histopathology and reflectance confocal microscopy features of photodamaged skin and actinic keratosis. ( 27298142 )
2016
18
Oral Pathology Quiz #90. Case Number 1. Frictional keratosis. ( 27159940 )
2016
19
Electrospun poly-l-lactide scaffold for the controlled and targeted delivery of a synthetically obtained Diclofenac prodrug to treat actinic keratosis. ( 27816622 )
2016
20
Clinical and Histopathological Investigation of Seborrheic Keratosis. ( 27081260 )
2016
21
Costs of Keratinocyte Carcinoma (Nonmelanoma Skin Cancer) and Actinic Keratosis Treatment in the Veterans Health Administration. ( 27465252 )
2016
22
Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. ( 27503482 )
2016
23
A new algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma based on in vivo analysis of optical properties by high-definition optical coherence tomography. ( 27311752 )
2016
24
Survey of Patient Satisfaction With Ingenol Mebutate Gel Treatment for Actinic Keratosis From a Community Dermatology Practice. ( 27784514 )
2016
25
Case of Japanese Hermansky-Pudlak syndrome patient with deeply invasive squamous cell carcinoma and multiple lesions of actinic keratosis on the face and neck. ( 27178242 )
2016
26
Prevalence of actinic keratosis among dermatology outpatients in Spain. ( 27445129 )
2016
27
Feasibility of daylight-mediated photodynamic therapy for actinic keratosis throughout the year in Central and South America: a meteorological study. ( 27061814 )
2016
28
Pigmentation-Independent Susceptibility Loci for Actinic Keratosis Highlighted by Compound Heterozygosity Analysis. ( 27646882 )
2016
29
Cytokeratin 17 immunoexpression in actinic keratosis (bowenoid and nonbowenoid) and in Bowen disease. ( 26740287 )
2016
30
Generalized keratosis pilaris-like eruptions in a chronic myelogenous leukemia patient treated with nilotinib. ( 27028020 )
2016
31
Defining Field Cancerization of the Skin Using Noninvasive Optical Coherence Tomography Imaging to Detect and Monitor Actinic Keratosis in Ingenol Mebutate 0.015%- Treated Patients. ( 27386042 )
2016
32
Expression of Podoplanin in Non-melanoma Skin Cancers and Actinic Keratosis. ( 27069135 )
2016
33
Randomized controlled trial comparing 35% trichloroacetic acid peel and 5-aminolevulinic acid photodynamic therapy for the treatment of multiple actinic keratosis. ( 28012181 )
2016
34
Dermoscopy of inverted follicular keratosis: study of 12 cases. ( 27018237 )
2016
35
Seborrheic Keratosis-like Lesions of the Cervix and Vagina: Report of a New Entity Possibly Related to Low-risk Human Papillomavirus Infection. ( 27792064 )
2016
36
Proteomic profiling reveals candidate markers for arsenic-induced skin keratosis. ( 27552035 )
2016
37
Mycosis fungoides patient accompanied actinic keratosis, actinic keratosis with squamous cell carcinoma transformation, and porokeratosis after NBUVB therapy - 1st case report and review of the literature. ( 27741114 )
2016
38
Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma. ( 27519350 )
2016
39
Bucher's indirect comparison of daylight photodynamic therapy with methyl aminolevulinate cream versus diclofenac plus hyaluronic acid gel for the treatment of multiple actinic keratosis. ( 27352420 )
2016
40
A sporadic case of Nagashima-type palmoplantar keratosis caused by gene mutation in SERPINB7. ( 27663160 )
2016
41
Egg membrane may protect eyes from ALA photodynamic therapy for eyelid actinic keratosis: Two case reports. ( 27350169 )
2016
42
Variables in Cryosurgery Technique Associated With Clearance of Actinic Keratosis. ( 28002105 )
2016
43
Keratosis lichenoides chronica mit untypischer klinischer PrAosentation und variblen histopathologischen Merkmalen. ( 27879072 )
2016
44
Successful Treatment of Keratosis Pilaris Rubra with Pulsed Dye Laser. ( 27282957 )
2016
45
Two cases of seborrheic keratosis with basal clear cells. ( 27790747 )
2016
46
Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography. ( 27095632 )
2016
47
Actinic Keratosis Pathogenesis Update and New Patents. ( 27142784 )
2016
48
Actinic Keratosis. ( 27046367 )
2016
49
Treatment of seborrheic keratosis in bilateral external auditory canal using fiber CO2 laser. ( 27888829 )
2016
50
Cost-Effectiveness and Cost-Utility Analysis of Ingenol Mebutate Versus Diclofenac 3% and Imiquimod 5% in the Treatment of Actinic Keratosis in Spain. ( 27130804 )
2016

Variations for Keratosis

Expression for Keratosis

Search GEO for disease gene expression data for Keratosis.

Pathways for Keratosis

GO Terms for Keratosis

Cellular components related to Keratosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 9.13 FLG IVL KRT10
2 intermediate filament GO:0005882 8.92 FLG KRT10 KRT17 KRT9
3 cytoplasm GO:0005737 10 CDKN2A FGFR3 GJA1 GJB2 IVL KRT10

Biological processes related to Keratosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.63 CDKN2A CTSC FGFR3 GJA1 MCM2 TP53
2 keratinization GO:0031424 9.62 IVL KRT10 KRT17 KRT9
3 keratinocyte differentiation GO:0030216 9.58 FLG IVL KRT10
4 replicative senescence GO:0090399 9.46 CDKN2A TP53
5 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress GO:1990440 9.43 MBTPS2 TP53
6 skin epidermis development GO:0098773 9.37 FLG KRT10
7 gap junction assembly GO:0016264 9.26 GJA1 GJB2
8 peptide cross-linking GO:0018149 9.13 FLG IVL KRT10
9 cornification GO:0070268 9.02 FLG IVL KRT10 KRT17 KRT9

Molecular functions related to Keratosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural constituent of epidermis GO:0030280 8.96 FLG KRT10
2 gap junction channel activity GO:0005243 8.62 GJA1 GJB2

Sources for Keratosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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