MCID: KRT036
MIFTS: 44

Keratosis, Seborrheic, Somatic malady

Categories: Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Keratosis, Seborrheic, Somatic

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Aliases & Descriptions for Keratosis, Seborrheic, Somatic:

Name: Keratosis, Seborrheic, Somatic 50 12
Keratosis, Seborrheic 46 68 25 37
Seborrheic Keratosis 11 13 48 66
 
Keratosis Seborrheica 46
Seborrheic Keratoses 46
Kerseb 68

Characteristics:

HPO:

62
keratosis, seborrheic, somatic:
Inheritance: autosomal dominant inheritance


Classifications:



External Ids:

OMIM50 182000
Disease Ontology11 DOID:6498
ICD1028 L82, L82.1
ICD9CM30 702.1
MeSH37 D017492
NCIt43 C9006
MedGen35 C0022603

Summaries for Keratosis, Seborrheic, Somatic

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UniProtKB/Swiss-Prot:68 Keratosis, seborrheic: A common benign skin tumor. Seborrheic keratoses usually begin with the appearance of one or more sharply defined, light brown, flat macules. The lesions may be sparse or numerous. As they initially grow, they develop a velvety to finely verrucous surface, followed by an uneven warty surface with multiple plugged follicles and a dull or lackluster appearance.

MalaCards based summary: Keratosis, Seborrheic, Somatic, also known as keratosis, seborrheic, is related to syringoma and vulvar seborrheic keratosis, and has symptoms including leser-trélat sign, leser-trélat sign and verrucae. An important gene associated with Keratosis, Seborrheic, Somatic is PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha), and among its related pathways are Chronic myeloid leukemia and Thyroid hormone signaling pathway. Affiliated tissues include skin, and related mouse phenotypes are hearing/vestibular/ear and renal/urinary system.

OMIM:50 Seborrheic keratoses are common benign epidermal lesion that can develop on any part of the body. (182000) more...

Related Diseases for Keratosis, Seborrheic, Somatic

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Diseases related to Keratosis, Seborrheic, Somatic via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 75)
idRelated DiseaseScoreTop Affiliating Genes
1syringoma30.0CLEC2A, KRT10
2vulvar seborrheic keratosis12.4
3inflamed seborrheic keratosis12.3
4inverted follicular keratosis11.7
5actinic keratosis11.5
6keratosis11.1
7megalencephaly-capillary malformation-polymicrogyria syndrome, somatic10.7MUT, PIK3CA
8cowden syndrome 510.7MUT, PIK3CA
9spermatogenic failure 610.7MUT, PIK3CA
10dermatosis papulosa nigra10.7
11melanoacanthoma10.6
12clear cell acanthoma10.6
13pancreatitis, pediatric10.6MTOR, PIK3CA
14pseudoangiomatous stromal hyperplasia10.6PIK3CA, TP53
15basal cell carcinoma10.6
16melanoma10.6
17pasli disease10.5FGFR3, TP53
18epidermal nevus, somatic10.5FGFR3, MUT, PIK3CA
19tamoxifen-related endometrial lesion10.5PIK3CA, TP53
20spongiotic dermatitis10.5FGFR3, MTOR, PIK3CA
21epidermolytic acanthoma10.5KRT10, MTOR
22familial renal oncocytoma10.5FGFR3, TP53
23scrapie10.4FGFR3, TP53
24intrahepatic bile duct adenoma10.4FGFR3, TP53
25papillary adenofibroma10.3MTOR, PIK3CA, TP53
26progesterone-receptor positive breast cancer10.3MTOR, PIK3CA, TP53
27glomangioma10.3CLEC2A, TP53
28encapsulated thymoma10.3MTOR, PIK3CA, TP53
29kidney sarcoma10.3PIK3CA, TP53
30zimmermann-laband syndrome 210.2MTOR, PIK3CA, TP53
31hemochromatosis type 210.2MTOR, PIK3CA
32epidermodysplasia verruciformis10.2
33lipomatosis10.2KRT10, RBP1, TP53
34acute retinal necrosis syndrome10.2MCM2, MCM7
35cryptosporidiosis10.2CLEC2A, TP53
36acanthoma10.2
37gigantism10.2
38breast fibroadenoma10.1FGFR3, KRT10, PIK3CA, TP53
39brachyolmia10.1MTOR, PIK3CA, TP53
40dowling-degos disease10.1
41cutaneous ganglioneuroma10.1
42adenocarcinoma10.1
43ganglioneuroma10.1
44psoriasis10.1
45lichen planus10.1
46lentigo maligna melanoma10.1
47complex lethal osteochondrodysplasia10.1KRT10, PIK3CA
48gliomatosis peritonei10.0MTOR, PIK3CA, TP53
49acute apical periodontitis10.0MCM2, MCM7, SALL1
50penis carcinoma in situ10.0FGFR3, LUM, PIK3CA, TP53

Comorbidity relations with Keratosis, Seborrheic, Somatic via Phenotypic Disease Network (PDN):


Hypertension, EssentialKeratosis

Graphical network of the top 20 diseases related to Keratosis, Seborrheic, Somatic:



Diseases related to keratosis, seborrheic, somatic

Symptoms for Keratosis, Seborrheic, Somatic

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Symptoms by clinical synopsis from OMIM:

182000

Clinical features from OMIM:

182000

HPO human phenotypes related to Keratosis, Seborrheic, Somatic:

id Description Frequency HPO Source Accession
1 verrucae HP:0200043

UMLS symptoms related to Keratosis, Seborrheic, Somatic:


leser-trélat sign

Drugs & Therapeutics for Keratosis, Seborrheic, Somatic

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Drugs for Keratosis, Seborrheic, Somatic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Lidocaine1168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
2
Epinephrine88651-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9

Interventional clinical trials:

(show all 13)
idNameStatusNCT IDPhase
1A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.RecruitingNCT02667236Phase 3
2A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic KeratosisRecruitingNCT02667275Phase 3
3An Open-Label Safety Study of A-101 SolutionRecruitingNCT02667288Phase 3
4Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic KeratosisCompletedNCT01214564Phase 2
5Study of A-101 for the Treatment of Seborrheic KeratosisCompletedNCT02260180Phase 2
6Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic KeratosisCompletedNCT01986920Phase 1, Phase 2
7Dose-Response Profile of A-101 in Subjects With Seborrheic KeratosisActive, not recruitingNCT02160626Phase 2
8Dermatosis Papulosa NigraCompletedNCT00710203
9Optical Biopsy of Human Skin in Conjunction With Laser TreatmentCompletedNCT00540566
10Analysis of Melanocytes (Pigment Cells) in Sun-Exposed SkinCompletedNCT00875381
11Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?Active, not recruitingNCT01159860
12In-vivo Optical Coherence Tomography Imaging in DermatooncologyActive, not recruitingNCT01680562
13Electrocautery vs Q-switch for Seborrheic KeratosisWithdrawnNCT02366559

Search NIH Clinical Center for Keratosis, Seborrheic, Somatic


Cochrane evidence based reviews: keratosis, seborrheic

Genetic Tests for Keratosis, Seborrheic, Somatic

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Genetic tests related to Keratosis, Seborrheic, Somatic:

id Genetic test Affiliating Genes
1 Keratosis, Seborrheic25

Anatomical Context for Keratosis, Seborrheic, Somatic

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MalaCards organs/tissues related to Keratosis, Seborrheic, Somatic:

34
Skin

Animal Models for Keratosis, Seborrheic, Somatic or affiliated genes

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MGI Mouse Phenotypes related to Keratosis, Seborrheic, Somatic:

39 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.5FGFR3, RBP1, SALL1, TGFB2, TP53
2MP:00053679.0FGFR3, MTOR, MUT, SALL1, TGFB2, TP53
3MP:00053818.6FGFR3, LUM, MCM2, MUT, SALL1, TGFB2
4MP:00053798.3MCM2, MTOR, MUT, OSMR, PIK3CA, RBP1
5MP:00107718.2FGFR3, LUM, MAGED1, MCM2, OSMR, PIK3CA
6MP:00053918.0FGFR3, LUM, MAGED1, PIK3CA, RBP1, TGFB2
7MP:00053977.7FGFR3, LUM, MCM2, MCM7, MTOR, OSMR
8MP:00036317.2FGFR3, MAGED1, MCM2, MTOR, MUT, PIK3CA
9MP:00053767.0FGFR3, LUM, MAGED1, MTOR, MUT, OSMR
10MP:00053877.0FGFR3, LUM, MAGED1, MCM2, MTOR, MUT
11MP:00053867.0FGFR3, LUM, MAGED1, MCM2, MTOR, MUT
12MP:00053846.8FGFR3, LUM, MAGED1, MCM2, MCM7, MTOR
13MP:00053786.7FGFR3, LUM, MCM2, MCM7, MTOR, MUT

Publications for Keratosis, Seborrheic, Somatic

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Variations for Keratosis, Seborrheic, Somatic

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UniProtKB/Swiss-Prot genetic disease variations for Keratosis, Seborrheic, Somatic:

68 (show all 11)
id Symbol AA change Variation ID SNP ID
1FGFR3p.Arg248CysVAR_004148rs121913482
2FGFR3p.Ser249CysVAR_004149rs121913483
3FGFR3p.Gly370CysVAR_004151rs121913479
4FGFR3p.Ser371CysVAR_004152rs121913484
5FGFR3p.Tyr373CysVAR_004153rs121913485
6FGFR3p.Lys650GluVAR_004160rs78311289
7FGFR3p.Lys650MetVAR_004161rs121913105
8PIK3CAp.Glu542LysVAR_026173rs121913273
9PIK3CAp.Glu545GlyVAR_026177rs121913274
10PIK3CAp.Glu545LysVAR_026178rs104886003
11PIK3CAp.His1047ArgVAR_026192rs121913279

Clinvar genetic disease variations for Keratosis, Seborrheic, Somatic:

5
id Gene Variation Type Significance SNP ID Assembly Location
1PIK3CANM_006218.3(PIK3CA): c.3140A> G (p.His1047Arg)single nucleotide variantPathogenicrs121913279GRCh37Chr 3, 178952085: 178952085
2PIK3CANM_006218.3(PIK3CA): c.1633G> A (p.Glu545Lys)single nucleotide variantPathogenicrs104886003GRCh37Chr 3, 178936091: 178936091
3FGFR3NM_000142.4(FGFR3): c.742C> T (p.Arg248Cys)single nucleotide variantPathogenicrs121913482GRCh37Chr 4, 1803564: 1803564
4FGFR3NM_000142.4(FGFR3): c.746C> G (p.Ser249Cys)single nucleotide variantPathogenicrs121913483GRCh37Chr 4, 1803568: 1803568

Expression for genes affiliated with Keratosis, Seborrheic, Somatic

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Search GEO for disease gene expression data for Keratosis, Seborrheic, Somatic.

Pathways for genes affiliated with Keratosis, Seborrheic, Somatic

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Pathways related to Keratosis, Seborrheic, Somatic according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6PIK3CA, TGFB2, TP53
29.6MTOR, PIK3CA, TP53
3
Show member pathways
9.5MTOR, OSMR, TP53
4
Show member pathways
9.5FGFR3, MTOR, PIK3CA, TGFB2
5
Show member pathways
9.4FGFR3, MTOR, PIK3CA, TP53
69.4FGFR3, MTOR, PIK3CA, TP53
7
Show member pathways
9.3MTOR, PIK3CA, TGFB2, TP53
89.2MCM7, RBP1, TP53
99.1FGFR3, MTOR, PIK3CA, TGFB2, TP53
109.1FGFR3, MTOR, PIK3CA, TGFB2, TP53
11
Show member pathways
9.1MAGED1, PIK3CA, TP53
129.0FGFR3, MTOR, OSMR, PIK3CA, TP53
138.9MCM2, MCM7, TGFB2, TP53
148.9LUM, MTOR, PIK3CA, TGFB2, TP53
15
Show member pathways
8.5MAGED1, MTOR, PIK3CA, TGFB2, TP53

GO Terms for genes affiliated with Keratosis, Seborrheic, Somatic

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Cellular components related to Keratosis, Seborrheic, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol 3-kinase complexGO:000594210.4MTOR, PIK3CA
2MCM complexGO:00425559.9MCM2, MCM7
3chromatinGO:00007858.7MAGED1, MCM2, MCM7

Biological processes related to Keratosis, Seborrheic, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1heart valve morphogenesisGO:000317910.2MTOR, TGFB2
2embryonic digestive tract developmentGO:00485669.9SALL1, TGFB2
3DNA unwinding involved in DNA replicationGO:00062689.7MCM2, MCM7
4phosphatidylinositol-mediated signalingGO:00480159.4FGFR3, MTOR, PIK3CA

Sources for Keratosis, Seborrheic, Somatic

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet