MCID: KRN004
MIFTS: 39

Kernicterus malady

Rare diseases, Fetal diseases, Neuronal diseases, Metabolic diseases, Cancer diseases, Skin diseases, Blood diseases categories

Aliases & Classifications for Kernicterus

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Aliases & Descriptions for Kernicterus:

Name: Kernicterus 10 45 47 12 51 2 65 36
Bilirubin Encephalopathy 10 45 51
Hyperbilirubinemic Encephalopathy 45
 
Kernicterus of Newborn Nos 10
Kernicterus of Newborn 10
Smallpox 65


Classifications:



External Ids:

Disease Ontology10 DOID:2382
NCIt42 C84799
MeSH36 D007647
Orphanet51 415286
ICD1027 P57, P57.8, P57.9

Summaries for Kernicterus

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Wikipedia:68 Kernicterus is a bilirubin-induced brain dysfunction. Bilirubin is a highly neurotoxic substance that... more...

MalaCards based summary: Kernicterus, also known as bilirubin encephalopathy, is related to crigler-najjar syndrome, type ii and crigler-najjar syndrome, type i. An important gene associated with Kernicterus is UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1), and among its related pathways are and Nicotine Pathway, Pharmacokinetics. Affiliated tissues include brain, globus pallidus and breast.

Related Diseases for Kernicterus

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Diseases in the Kernicterus family:

Kernicterus Due to Isoimmunization

Diseases related to Kernicterus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idRelated DiseaseScoreTop Affiliating Genes
1crigler-najjar syndrome, type ii30.1UGT1A1, UGT1A4, UGT1A6, UGT1A9
2crigler-najjar syndrome, type i30.0UGT1A1, UGT1A4, UGT1A6, UGT1A9
3fetal erythroblastosis28.2ALB, G6PD, PKM, RHCE, SLC4A1, UGT1A1
4neonatal jaundice10.6
5kernicterus due to isoimmunization10.5
6glucose-6-phosphate dehydrogenase deficiency10.5
7encephalopathy10.5
8brain injury10.2
9cerebritis10.2
10blood group incompatibility10.2
11neonatal period electroclinical syndrome10.2G6PD, UGT1A1
12hepatitis10.2
13neuronitis10.2
14hemoglobinuria10.2G6PD, UGT1A1
15conjunctival pigmentation10.1G6PD, UGT1A1
16diaphragm disease10.1UGT1A1, UGT1A6
17snyder-robinson syndrome10.1G6PD, UGT1A1
18kosztolanyi syndrome10.1ALB, G6PD
19klippel-feil syndrome10.1ALB, UGT1A1
20paralytic lagophthalmos10.1ALB, G6PD
21dihydropyrimidine dehydrogenase deficiency10.1UGT1A1, UGT1A6
22hemoglobin h disease, nondeletional10.1G6PD, UGT1A1
23sensory organ benign neoplasm10.1ALB, G6PD
24encephalopathy, neonatal severe10.1
25speech and communication disorders10.1
26acquired metabolic disease10.1
27bilirubin metabolic disorder10.1
28prion disease10.1
29neurologic diseases10.1
30congenital hypoplastic anemia10.0G6PD, SLC4A1
31presbyopia10.0G6PD, SLC4A1, UGT1A1
32goiter10.0G6PD, UGT1A1, UGT1A6
33hyperbilirubinemia, familial transient neonatal10.0
34cerebral palsy10.0
35hemolytic anemia10.0
36rheumatic fever10.0
37hereditary spherocytosis10.0
38congenital hypothyroidism10.0
39central pontine myelinolysis10.0
40aphasia10.0
41congenital hemolytic anemia10.0
42hypothyroidism10.0
43viral hepatitis10.0
44athetosis10.0
45lucey-driscoll syndrome10.0
46visceral steatosis10.0
47anoxia10.0
48endotheliitis10.0
49fulminant viral hepatitis10.0
50sickle cell anemia10.0G6PD, UGT1A1, UGT1A6

Graphical network of the top 20 diseases related to Kernicterus:



Diseases related to kernicterus

Symptoms for Kernicterus

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Drugs & Therapeutics for Kernicterus

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Drugs for Kernicterus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BilirubinPhase 495635-65-45280352
Synonyms:
(4Z,15Z)-Bilirubin IXa
(Z,Z)-Bilirubin IXa
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
 
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Bilirubin
Bilirubin IX-alpha
Cholerythrin
Hematoidin
2Rho(D) Immune GlobulinPhase 4198
3Immunoglobulins, IntravenousPhase 4203
4
Mentholapproved17482216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
999 Itch Relief
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
Absorbine Back Therapeutic Pain Relief
Absorbine Jr
Absorbine Jr Ultra Strength Pain Relieving
Absorbine Jr.
Absorbine Jr. Back
Algomend Pain Relief
Alhua Huogan Pain Relieving Patch
Aloemint Skin Aid
Amar Ice
Analgesic
Anc Neverpain External Analgesic
Anti Itch
Army Health Pain Reliever
Arthri-support
Arthri-zen Relief
Arthripain Relief
Arthritis Relief
Aspercreme Heat
Aspercreme Max No Mess Roll On
Assured Cold N Hot Pain Relief Menthol
Assured Extra Strength Cold N Hot
Assured Ice Cold Topical Analgesic
Assured Muscle Rub
Assured Pain Relief Hot Menthol
Atopalm Pain Relieving
Aurorae Healing Pain Relieving Roll-on
Avapta
Avedana Pain Relieving Roll On
Avedana Pain-relieving
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
Babyganics Cold Relief Chest Rub
Barox
Barox BODY CARE MASSAGE
Barox Body Care Massage Relax Refresh Revital
Being Well Extra Strength Menthol Heat
Bengay Ultra Strength Large Size
Bengay Ultra Strength Pain Relieving Large Size
Bengay Ultra Strength Pain Relieving Regular Size
Bengay Ultra Strength Regular Size
Bengay Vanishing Scent
Bengay Zero Degrees Menthol Pain Relieving
Bentasil SUGAR FREE BLACKCURRANT SOFT Texture
Bentasil SUGAR FREE CHERRY SOFT Texture
Bentasil SUGAR FREE HONEY LEMON SOFT Texture
Berri-freez
Besthealth Cherry
Besthealth Cough Suppressant Sugar Free Black Cherry Flavor
Besthealth Cough Suppressant Sugar Free Honey Lemon Flavor
Besthealth Honey Lemon
Besthealth Menthol
Bio 2 Brazilian Heat Brazilian Heat
Bio-scriptives Extreme Pr
Bioblast Pain Relief
Bioflexor
Biofreeze
Biofreeze Colorless
Biofreeze Colorless Roll-on
Biofreeze Roll-on
Biorelief Ice Pain Relieving
Blistex Ivarest Medicated Poison Ivy Cleansing Foam
Blue Gel Pain Relieving
Blue Ice
Blue Ice Analgesic
Blue Ice Analgesic Gel
Blue Ice Pain Relieving
Body
Budpack Muscle Rub
Budpak Muscle Rub
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Canker Complete Canker Sore Relief
Caswell No. 540
Celadrin
Cepacol Sore Throat From Post Nasal Drip
Cepacol Sore Throat Regular Strength
Ching Wan Hung Soothing Herbal Balm
Choice Personal Care Theraputic Blue Ice
Cold Hot Patch
Cold Spot Point Relief
Coldaid
Cool N Heat Patch For Back Extra Strength
Coralite Extra Strength Menthol Pain Relief Sleeve - Knee
Coralite Extra Strength Menthol Pain Relief Sleeve - Wrist
Coralite Pain Relief
Counteract Cough Drops Honey Lemon
Counteract Cough Drops Orchard Cherry
Cryogel Island Rain Natural Pain Relieving Vitaminerals
Cvs Cold Hot Medicated
Cvs Soothing Itch Relief
Cvs Sore Muscle Rub Vanishing Scent
Cvs Therapeutic Menthol Gel
Cvs Therapeutic Menthol Pain Reliever
Cvs Tropical Citrus Cough
Cvs Ultra Strength Pain Relieving
Cvs Vanishing Scent Muscle Rub
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
Dg Health Extra Strength Medicated
Dg Health Pain Relieving
Dg Ice Cold Analgesic
Diapedic Foot Treatment
DivK1c_000820
Dorflex Icy Hot Flexible, Large
Dorflex Icy Hot Flexible, Small
Dorflex Icy Hot Flexible, XL
Dr. Blue
Dt Ice Cold Analgesic
Dual Action Cherry Cough Suppressant Oral Anesthetic
Dynafreeze
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
Easy
Eb301ap Pain Relief
Eb301ct Bruise Pain Relief
Eb302 Arthritis Relief
Ecolyptus Pain Relieving Muscle Rub
Efac Pain Relieving
Elgin Pain Relief
Equaline Blue Ice Pain Relieving
Equate Menthol Extra Strength
Eros Iron Man
Eucalyptamint
Eucerin Calming Itch Relief Treatment
Extra Strength Cold N Hot Pain Relief Medicated
Extra Strength Pain Relief Therapy
Extra Strength Stopain Cold Pain Relieving
Extra Strength Stopain Cold Pain Relieving Roll On
FEMA No. 2665
Family Care Maximum Strength Medicated Anti Itch
Fast Freeze
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
Flexall Pain Relieving
Flexgen
Fluaid
Foot Works Achy Foot Massager Pain Relieving
Gold Bond Foot Extra Strength
Gold Bond Medicated Foot
Gold Bond Pain Relieving Foot
Gold Bond Pain Relieving Foot Roll On
Green Bamboo
Green Guard Cough Drop Relief
HMS1922G13
HMS2092L14
HMS502I22
HSDB 5662
HSDB 593
Halls Apple Cider
Halls Butterscotch
Halls Cherry
Halls Extra Strong Menthol
Halls Honey Lemon
Halls Ice Peppermint
Halls MENTHO-LYPTUS
Halls Melon Splash
Halls Menthol
Halls Mentholyptus
Halls Mocha Mint
Halls Naturals Honey Lemon Chamomile
Halls Plus Cherry
Halls Plus Honey
Halls Plus Strawberry
Halls Spearmint
Halls Strawberry
Halls Sugar Free Black Cherry
Halls Sugar Free Citrus Blend
Halls Sugar Free Extra Strong Menthol
Halls Sugar Free Honey Berry
Halls Sugar Free Honey Lemon
Halls Sugar Free Mountain Menthol
Halls Tropical Fruit
Hallsmelon Splash Melon Splash
Hallssugar Free Extra Sugar Free Extra Strong Menthol
Han Honey Loquat Syrup
Hanbang Cataplasma
Harmon Extra Strength Pain Relieving
Harmon Extra Strength Pain Relieving Roll-on
Headache crystals
Health Smart Medicated Foot
Herbion Naturals Honey Lemon
Herbion Naturals Honey Lemon Cough Drops
Herbion Naturals Honey-Lemon Cough Drops
Herbion Naturals Mint Cough Drops
Herbion Naturals Orange
Herbion Naturals Orange Cough Drops
Hexahydrothymol
Hielo Ardiente
Honibe
 
Hot Ice Soothing Analgesic Gel
Huitomi Slimming Sports
Humphreys Bendito Alcoholado
I06-1216
I14-7371
IDI1_000820
Ice
Ice Cold Analgesic
Ice Cold Topical Analgesic Gel
Ice External Analgesic Leader
Ice Quake
Ice Quake Muscle Rub
Icy Cool Maximum Strength
Icy Hot
Icy Hot Back
Icy Hot Medicated
Icy Hot Medicated No Mess Applicator
Icy Hot Medicated Roll Large
Icy Hot Medicated Roll Medium
Icy Hot Medicated Roll, Large
Icy Hot Medicated Roll, Medium
Icy Hot Medicated, Advanced Relief
Icy Hot Medicated, Back
Icy Hot Medicated, XL
Icy Hot Naturals
Icy Hot Power Gel
Icy Hot Vanishing Scent
Icyhot Medicated
Imada Four Seasons Safe Analgesic Balm
Jakemans Blueberry
Jakemans Cherry
Jakemans Peppermint
K2 Cold Therapy
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
Kay Medic Menthol Pain Relief
Kool Comfort
Kool Comfort Pain Relieving Roll-on
Kpp Triple Action
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
La Jiao Feng Shi Gao
Lander Polar Ice
Leader Cough Drops Cherry Flavor
Leader Cough Drops Honey Lemon
Leader Cough Drops Menthol Flavor
Leader Extra Strength Medicated Pain Relief Patch
Leader Sugar Free Cough Drops Black Cherry
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
Linkus Lozenges Cough Suppressant/Oral Anesthetic
Low Sugar Cherry Flavor Fishermans Friend Menthol Cough Suppressant
Ludens Honey Lemon Throat Drops
Ludens Honey Licorice Throat Drops
Ludens Original Menthol Throat Drops
Lurosil
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Makesense Extra Strength Muscle Rub
Maxfit Freeze Gel
Maybelline New York Baby Lips Dr Rescue Medicated Balm
Medi First Plus Cherry Cough Drops
Medi-first Cherry Cough Drops
Medic Ice
Medicated Body Powder
Medicated Pain Relief
Mediflex
Medique Medikoff Drops
Medique Sugar Free Medikoff Drops
Meditowel PAIN RELIEF
Meijer Cherry Cough Drops
Meijer Honey Lemon Cough Drops
Meijer Menthol Cough Drops
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol Fresh Cough Suppressant
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Mentholatum Pain Relief Extra Strength
Mentholatum Sports Pain Relief Cold
Menthomenthol
Menthyl alcohol
Mineral Ice Pain Relieving
Miracle Foot Repair
Miracle Foot Repair Cream
Miracle Of Aloe Rub Roll On
Miracle Pain Cream
Moisture Therapy Anti-Itch
MolPort-000-849-729
MolPort-001-793-392
Moore Medical Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Black Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Menthol Cough Suppressant/anesthetic Drops
Mr Dudleys Topical Pain Relief
Muscle
Muscle Rub Ultra Strength Pain Relieving
Myo-breathe
Myorx Low Dose Pain Relieving
Myorx Pain Relieving
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Nan San Easy Flex Pain Relieving
Natural Cherry Honey Herb Throat Drops
Natural Herb cough drop
Natural Honey Herb Cough Suppressant Throat Drops
Natural Lemon Mint Herb Throat Drops
Natural Pain Relieving Lavender Breeze Cryogel
Natures Choice Cool Hot Ice
Natures Sunshine Products Everflex Topical Analgesic Pain Relief
Neoisomenthol
Nice Assorted
Nice Cherry
Nice Citrus
Nice Cool Mint
Nice Honey Lemon
Nice Menthol
No Pain More Gain
North Cough Drop
Numotizine
Olbas Lozenges Maximun Strength
Olbas Pastilles
Original Extra Strong All Natural Fishermans Friend Menthol Cough Suppressant
Ortho-nesic
Osmoflex
Oxyrub Pain Relief
Pain Relief Balmpreferred Plus Ph Preferred Plus Pharmacy
Pain Relief Therapy Patch
Pain Reliever
Pain Relieving
Pain Relieving Analgesic
Pain Relieving Patch
Pain Relieving Patch Ultra Strength
Pain Relieving Patch Ultra Strength ULTRA STRENGTH
Panitrol XR
Paraid Extra Strength Menthol Pain Relief Sleeve Knee Large Ankles Elbows
Patch Scherer Labs
Patch Walgreens
Peppermint camphor
Perfect Purity Hotice
Perfect Purity Medicated Foot Powder
Perform
Personal Care Extra Strength Cold Hot
Personal Care Ice Cold
Plaster MandAHerbalPlaster
Po Sum On Medicated
Polar Frost Cold
Power Relief
Preferred Plus Body Powder
Premier Value Medicated Foot Powder
Q Health Pain Relief Spray
Quickflex
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Raw Heat
Raw Ice
Reactice Reactivating Ice Baume
Red Lion Relief
Relief Pain Relieving Cream
Rexall Vanishing Scent Pain Relieving
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Screamin Menthol Toast
Sella Natural
Skin So Soft Bug Guard Plusitch Relief itch relief
Smith Bros Honey Lemon Cough Drops
Smith Bros Menthol Eucalyptus Cough Drops
Smith Bros Sugar-free Black Cherry Cough Drops
Sof Skin Icy Blue
Sofskin Ice Analgesic
Sombra Cool Therapy
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Stopain Cold Pain Relieving
Stopain Cold Professional Strength Pain Relieving
Stopain Extra Strength Pain Relieving
Sub-zero COOL PAIN RELIEVING
Sugar Free Cherry Fishermans Friend Menthol Cough Suppressant
Sugar Free Cherry Herb Throat Drops
Sugar Free Lemon Mint Herb Throat Drops
Sugar Free Mountain Herb Cough Suppressant Throat Drops
Sugar Free Original Swiss Herb Cough Suppressant Throat Drops
Sugar Free Refreshing Mint Fishermans Friend Menthol Cough Suppressant
Sugar Free Swiss Cherry Herb Throat Drops
The Medicine Shoppe Extra Strength Pain Relieving
The Original Natural Herb Cough Drops
Therafreeze
Theraid
Therapeutic Relief Preferred Plus Pharmacy
Theraplus Plus
Throat Coat
Tianhe Guben Yaoshen Tie Gao
Top Care Medicated
Topcare Medicated
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
Ultra Strength Stopain Pain Relieving
Us Favorite Cold Pain Relieving
Vaporizing Colds Rub
Vicks Vapodrops Cough Relief
Vitaminerals Inc. Cryogel Natural Pain Relieving
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
Walgreens Aloe Vera Cooling
Watermelon Frost Sore Throat
Wellpatch Backache Pain Relief
Xtracare Ice Cold Topical Analgesic Gel
Youngevity Invision CM
Yun Xiang Jing
ZINC01482164
Zhong Hua Jiu Patch
Zims Arnica Max
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy of High-dose Intravenous Immunoglobulin Therapy for Hyperbilirubinemia Due Rh Hemolytic DiseaseCompletedNCT00288600Phase 4
2Use of a New Phototherapy Device (BBloo®) for the Treatment of Hyperbilirubinemia in the Newborn InfantRecruitingNCT02156050Phase 4
3Efficacy of Yinzhihuang Oral Liquid on Indirect Bilirubin of Neonates With Glucose-6-phosphate Dehydrogenase DeficiencyRecruitingNCT02594904Phase 4
4Efficacy and Safety of Stannsoporfin in NeonatesCompletedNCT02685137Phase 3
5Determining Prevalence of Acute Bilirubin Encephalopathy in Developing CountriesCompletedNCT01754688
6Follow-up of Extreme Neonatal Hyperbilirubinemia in 5-10 Year Old Children: a Danish Population Based StudyCompletedNCT01599611
7Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm InfantsRecruitingNCT02691156
8Resting State Functional Magnetic Resonance Imaging Study of Jaundice Infants Before and After Light Treatment.RecruitingNCT02224586
9Implementation of a Transcutaneous BilirubinometerRecruitingNCT01622699
10New Phototherapy Device to Treat Patients With Crigler-Najjar DiseaseActive, not recruitingNCT02356978

Search NIH Clinical Center for Kernicterus


Cochrane evidence based reviews: Kernicterus

Genetic Tests for Kernicterus

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Anatomical Context for Kernicterus

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MalaCards organs/tissues related to Kernicterus:

33
Brain, Globus pallidus, Breast, Liver, Endothelial, Skin

Animal Models for Kernicterus or affiliated genes

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Publications for Kernicterus

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Articles related to Kernicterus:

(show top 50)    (show all 335)
idTitleAuthorsYear
1
Serum unbound bilirubin as a predictor for clinical kernicterus in extremely low birth weight infants at a late age in the neonatal intensive care unit. (25638486)
2015
2
Jaundice and kernicterus in the moderately preterm infant. (24182955)
2013
3
The Italian Registry of kernicterus and hyperbilirubinaemia. (22958040)
2012
4
Fatal kernicterus in a girl deficient in glucose-6-phosphate dehydrogenase: a paradigm of synergistic heterozygosity. (19324225)
2009
5
Unbound bilirubin: a better predictor of kernicterus? (18160727)
2008
6
Kernicterus in an adult dog. (17491082)
2007
7
Kernicterus associated with hereditary spherocytosis and UGT1A1 promoter polymorphism. (16735790)
2006
8
Magnetic resonance imaging of the brain in children with chronic kernicterus. (22266622)
2006
9
Hyperintense globus pallidus on T1-weighted MR imaging in acute kernicterus: is it common or rare? (15565320)
2005
10
Bronze baby syndrome and the risk of kernicterus. (16188824)
2005
11
Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin. (15936300)
2005
12
Urgent clinical need for accurate and precise bilirubin measurements in the United States to prevent kernicterus. (14726464)
2004
13
Research on prevention of bilirubin-induced brain injury and kernicterus: National Institute of Child Health and Human Development conference executive summary. 2003. (15231933)
2004
14
Cost-effectiveness of strategies that are intended to prevent kernicterus in newborn infants. (15466085)
2004
15
Kernicterus and G6PD deficiency--a case series from Oman. (12729287)
2003
16
Breast-feeding, neonatal jaundice and kernicterus. (12208098)
2002
17
System-based approach to management of neonatal jaundice and prevention of kernicterus. (12006952)
2002
18
Preterm infants with athetoid cerebral palsy: kernicterus? (11207234)
2001
19
From the Centers for Disease Control and Prevention. Kernicterus in full-term infants--United States, 1994-1998. (11474907)
2001
20
Risk factors for kernicterus in term babies with non-hemolytic jaundice. (11463962)
2001
21
Kernicterus threatens healthy newborns. (11424865)
2001
22
Kernicterus in a full-term infant: the need for increased vigilance. (7724333)
1995
23
Kernicterus in preterm infants; lest we forget (to turn on the lights) (1408550)
1992
24
Assessing the risk of kernicterus using nuclear magnetic resonance. (2369802)
1990
25
Auditory brainstem response in patients with a history of kernicterus. (3272525)
1988
26
Kernicterus in the premature neonate. (3333255)
1987
27
Neonatal bilirubin toxicity. A review of kernicterus and the implications of drug-induced bilirubin displacement. (3304769)
1987
28
Value and limitations of bilirubin binding capacity in predicting the development of kernicterus. (6466218)
1984
29
Kernicterus at low levels of serum bilirubin: the impact of bilirubin albumin-binding capacity. A 10-year retrospective survey. (7199940)
1982
30
Kernicterus: effect on choline acetyltransferase, glutamic acid decarboxylase and tyrosine hydroxylase activities in the brain of the Gunn rat. (6105009)
1980
31
Singapore kernicterus. (262490)
1979
32
The pathochemistry of kernicterus. (43803)
1979
33
Absence of kernicterus in low-birth weight infants from 1971 through 1976: comparison with findings in 1966 and 1967. (714577)
1978
34
Breakdown of blood/brain barrier in kernicterus. (67529)
1977
35
An electron microscopic and radioautographic study on experimental kernicterus. I. Bilirubin transport via astroglia. (5815579)
1969
36
Serum albumin reserve PSP dye binding capacity in infants with kernicterus. (6067403)
1967
37
Risk of kernicterus in newborn infants with a high level of conjugated bilirubin. (6007580)
1966
38
KERNICTERUS IN NEWBORN RABBITS. (14266216)
1965
39
PREVENTION OF CEREBRAL DAMAGE (KERNICTERUS) FROM FOETO-MATERNAL INCOMPATIBILITY; ANTENATAL ASPECTS. (14062989)
1963
40
Kernicterus in premature infants associated with low concentrations of bilirubin in the plasma. (13553575)
1958
41
Clinical kernicterus and congenital hypothyroidism. (13493800)
1958
42
Congenital hemolytic anemia in the newborn; relationship to kernicterus. (13478296)
1957
43
Experimental studies on the pathogenesis of kernicterus. (13484304)
1957
44
Congenital cirrhosis of the liver with kernicterus; report of two cases in siblings with a discussion of the relationship to so-called neonatal hepatitis and to iso-immunization disease. (13268609)
1955
45
Prevention of death and crippling from kernicterus in hemolytic disease of the newborn. (13221977)
1954
46
Cerebrospinal fluid bilirubin in the neonatal period with special reference to the development of kernicterus; preliminary report. (13217811)
1954
47
The mechanism of production of kernicterus. (13000553)
1952
48
Kernicterus. (14819084)
1951
49
Pathogenesis of Kernicterus. (17800122)
1946
50
Case of Kernicterus. (19992043)
1939

Variations for Kernicterus

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Expression for genes affiliated with Kernicterus

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Search GEO for disease gene expression data for Kernicterus.

Pathways for genes affiliated with Kernicterus

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Pathways related to Kernicterus according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
AhR pathway (WikiPathways)
Show member pathways
9.6
2
Show member pathways
9.6UGT1A4, UGT1A9
39.1UGT1A4, UGT1A6, UGT1A9
4
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
5
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
6
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
7
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
8
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
9
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
10
Show member pathways
8.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
117.8G6PD, PKM, UGT1A1, UGT1A4, UGT1A6, UGT1A9
12
Show member pathways
6.9ALB, G6PD, PKM, SLC4A1, UGT1A1, UGT1A4

GO Terms for genes affiliated with Kernicterus

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Cellular components related to Kernicterus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulumGO:00057839.0UGT1A1, UGT1A4, UGT1A6, UGT1A9
2endoplasmic reticulum membraneGO:00057898.7UGT1A1, UGT1A4, UGT1A6, UGT1A9
3extracellular exosomeGO:00700627.6ALB, G6PD, PKM, SLC4A1, UGT1A6, UGT1A9

Biological processes related to Kernicterus according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1heme catabolic processGO:004216710.3UGT1A1, UGT1A4
2flavone metabolic processGO:005155210.3UGT1A1, UGT1A9
3porphyrin-containing compound metabolic processGO:000677810.2UGT1A1, UGT1A4
4retinoic acid metabolic processGO:004257310.1UGT1A1, UGT1A9
5organ regenerationGO:00311009.8PKM, UGT1A1
6flavonoid biosynthetic processGO:00098139.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
7negative regulation of fatty acid metabolic processGO:00459229.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
8flavonoid glucuronidationGO:00526969.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
9xenobiotic glucuronidationGO:00526979.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
10negative regulation of glucuronosyltransferase activityGO:19042249.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
11negative regulation of cellular glucuronidationGO:20010309.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
12cellular glucuronidationGO:00526959.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
13cellular response to hormone stimulusGO:00328709.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
14drug metabolic processGO:00171449.2UGT1A1, UGT1A4, UGT1A6, UGT1A9
15xenobiotic metabolic processGO:00068059.1UGT1A1, UGT1A4, UGT1A6, UGT1A9
16small molecule metabolic processGO:00442816.9ALB, G6PD, PKM, SLC4A1, UGT1A1, UGT1A4

Molecular functions related to Kernicterus according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1enzyme inhibitor activityGO:00048579.6UGT1A1, UGT1A9
2transferase activity, transferring hexosyl groupsGO:00167589.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
3retinoic acid bindingGO:00019729.1UGT1A1, UGT1A4, UGT1A6, UGT1A9
4glucuronosyltransferase activityGO:00150209.1UGT1A1, UGT1A4, UGT1A6, UGT1A9
5enzyme bindingGO:00198998.9UGT1A1, UGT1A4, UGT1A6, UGT1A9
6protein heterodimerization activityGO:00469828.8UGT1A1, UGT1A4, UGT1A6, UGT1A9
7protein homodimerization activityGO:00428037.6G6PD, SLC4A1, UGT1A1, UGT1A4, UGT1A6, UGT1A9

Sources for Kernicterus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet