MCID: KDN013
MIFTS: 21

Kidney Hypertrophy malady

Summaries for Kidney Hypertrophy

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33MalaCards
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MalaCards: Kidney Hypertrophy, also known as hypertrophy of kidney, is related to bronchopneumonia and arteriosclerosis. An important gene associated with Kidney Hypertrophy is TGFB1 (transforming growth factor, beta 1), and among its related pathways are Integrated Pancreatic Cancer Pathway and Endocytosis. Affiliated tissues include liver, brain and kidney.

Aliases & Classifications for Kidney Hypertrophy

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 57SNOMED-CT
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Aliases & Descriptions:

kidney hypertrophy 8 10
hypertrophy of kidney 61


External Ids:

Disease Ontology8 DOID:9622
SNOMED-CT57 197800004, 88531004
ICD9CM27 593.1

Related Diseases for Kidney Hypertrophy

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Kidney Hypertrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1bronchopneumonia10.0
2arteriosclerosis10.0
3uremia10.0
4glomerulonephritis10.0TGFB1

Clinical Features for Kidney Hypertrophy

Drugs & Therapeutics for Kidney Hypertrophy

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Kidney Hypertrophy

Drug clinical trials:

Search ClinicalTrials for Kidney Hypertrophy

Search NIH Clinical Center for Kidney Hypertrophy

Search CenterWatch for Kidney Hypertrophy

Genetic Tests for Kidney Hypertrophy

Anatomical Context for Kidney Hypertrophy

Sources:
33MalaCards
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MalaCards organs/tissues related to Kidney Hypertrophy:

33
Liver, Brain, Kidney, Prostate

Animal Models for Kidney Hypertrophy or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Kidney Hypertrophy

Sources:
51PubMed
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Articles related to Kidney Hypertrophy:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease. (24028070)
2014
2
Sex differences in the association between serum uric acid levels and cardiac hypertrophy in patients with chronic kidney disease. (24089265)
2013
3
Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease. (21242674)
2011
4
Plasma adiponectin concentration and left ventricular hypertrophy in kidney transplant patients. (20964715)
2011
5
A comparison of the effects of ramipril and losartan on blood pressure control and left ventricle hypertrophy in patients with autosomal dominant polycystic kidney disease. (20722556)
2010
6
Moderate chronic kidney disease and left ventricular hypertrophy after aortic valve replacement for aortic valve stenosis. (20304136)
2010
7
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats. (20404054)
2010
8
Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis. (19211686)
2009
9
Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. (19414634)
2009
10
The relationship between insulin resistance and left ventricular hypertrophy in patients with early chronic kidney disease.]. (20193515)
2009
11
Is valvular calcification a part of the missing link between residual kidney function and cardiac hypertrophy in peritoneal dialysis patients? (19713292)
2009
12
Left ventricular hypertrophy in mild and moderate reduction in kidney function determined using cardiac magnetic resonance imaging and cystatin C: the multi-ethnic study of atherosclerosis (MESA). (18845370)
2008
13
Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension. (18423813)
2008
14
Effect of sirolimus on left ventricular hypertrophy in kidney transplant recipients: a 1-year nonrandomized controlled trial. (18585837)
2008
15
Left ventricular hypertrophy in predialysis chronic kidney disease: impact of cardiomuscular stress markers]. (18186229)
2007
16
Relationship of brain natriuretic peptide to renal function and left ventricular hypertrophy in patients with chronic kidney disease]. (18396626)
2007
17
Risk factors and pathogenetic mechanisms of left ventricular hypertrophy in progressive chronic kidney disease and after transplantation of the kidney]. (17684964)
2007
18
Association between biomarkers of inflammation and left ventricular hypertrophy in moderate chronic kidney disease. (17474556)
2007
19
Development of hypertension and kidney hypertrophy in transgenic mice overexpressing ARAP1 gene in the kidney. (16801480)
2006
20
Renin-angiotensin system blockade prevents the increase in plasma transforming growth factor beta 1, and reduces proteinuria and kidney hypertrophy in the streptozotocin-diabetic rat. (15526251)
2004
21
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. Part II--Kidney hypertrophy and calcium deposition. (15161952)
2004
22
Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to heparin. (15126919)
2004
23
The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption II--kidney hypertrophy, vitellogenin and spiggin induction. (15588642)
2004
24
New cardiovascular risk factors and chronic kidney disease. Hypertrophy of the left ventricle. Atrial fibrillation. Smoking. Obesity. Emerging cardiovascular risk factors: homocysteine, Reactive C protein. Fibrinogen]. (15696897)
2004
25
No effect of angiotensin-converting enzyme gene polymorphism on disease progression and left ventricular hypertrophy in autosomal dominant polycystic kidney disease. (14600431)
2003
26
Left ventricular hypertrophy in hypertensive patients with autosomal dominant polycystic kidney disease: influence of blood pressure and humoral and neurohormonal factors. (10878400)
2000
27
Reversal of left ventricular hypertrophy with angiotensin converting enzyme inhibition in hypertensive patients with autosomal dominant polycystic kidney disease. (10344347)
1999
28
The effect of angiotensin-converting enzyme inhibitors on left ventricular hypertrophy in patients with chronic glomerulonephritis and pronounced kidney failure]. (9297267)
1997
29
Isthmus hypertrophy mimics tumour in horseshoe kidney: a case report. (8713567)
1996
30
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. (8603776)
1996
31
An evaluation of the role of polyamines in different models of kidney hypertrophy in mice. (7474658)
1995
32
Inhibition of renal ornithine decarboxylase activity fails to reduce kidney size and urinary albumin excretion in diabetic rats with manifest kidney hypertrophy. (7796931)
1995
33
Antihypertensive effect of sesamin. II. Protection against two-kidney, one-clip renal hypertension and cardiovascular hypertrophy. (8845824)
1995
34
Renal proteinases and kidney hypertrophy in experimental diabetes. (7926340)
1994
35
Morphometric analysis of kidney hypertrophy in rats after chronic potassium depletion. (1566879)
1992
36
Transient increase in renal insulin-like growth factor binding proteins during initial kidney hypertrophy in experimental diabetes in rats. (1377139)
1992
37
Kidney IGF-I and renal hypertrophy in GH-deficient diabetic dwarf rats. (1616029)
1992
38
Increased ornithine decarboxylase activity in kidneys undergoing hypertrophy in experimental diabetes. (1511780)
1992
39
Vasopressin-dependent kidney hypertrophy: role of urinary concentration in protein-induced hypertrophy and in the progression of chronic renal failure. (2042645)
1991
40
Characterization of beta-adrenergic receptor subtypes in androgen-induced mouse kidney hypertrophy using a new high-affinity ligand, [125I]iodocyanopindolol. (6299377)
1983
41
Increased beta-adrenergic receptor complement in androgen-induced mouse kidney hypertrophy. (6269651)
1981
42
Regulation of compensatory kidney hypertrophy by its own products. (894611)
1977
43
The influence of salt intake on glomerular count in compensatory kidney hypertrophy in rats of different ages. (954972)
1976
44
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy. (4119904)
1972
45
Immunochemical studies on kidney hypertrophy of the rat. (13954727)
1962
46
On renal failure complicating surgical diseases (laparotomy etc.), with special regard to conservative treatment, and the need for the artificial kidney (dialyser, ultrafilter) in rational renal therapy; acute tubular nephritis, chronic pyelonephritis and prostatic hypertrophy with urinary retention. (14398036)
1954
47
Clinico-pathological conference: hypoplasia of the kidneys secondary to chronic pyelonephritis; acute bronchitis; myocardial hypertrophy; fatty metamorphosis of the liver; rickets. (14870327)
1951
48
WEEKLY clinicopathological exercises: chronic pyelonephritis severe (with uremia); atrophy of the right kidney, hypertrophy of left; bronchopneumonia; aortic arteriosclerosis, severe, ascending arch, with short localized dissection; calcareous aortic stenosis. (14863577)
1951
49
Kidney hypertrophy in B complex deficiency. (21024173)
1946
50
Congenital Hydronephrosis of both Kidneys; both Ureters dilated, with Hypertrophy of Bladder. (19979448)
1916

Genetic Variations for Kidney Hypertrophy

Expression for genes affiliated with Kidney Hypertrophy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Kidney Hypertrophy

Search GEO for disease gene expression data for Kidney Hypertrophy.

Pathways for genes affiliated with Kidney Hypertrophy

Sources:
38NCBI BioSystems Database, 30KEGG
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Pathways related to Kidney Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4TGFB1, POLR1A
29.1TGFB1, ARAP1

Compounds for genes affiliated with Kidney Hypertrophy

GO Terms for genes affiliated with Kidney Hypertrophy

Products for genes affiliated with Kidney Hypertrophy

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Kidney Hypertrophy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet