MCID: KDN013
MIFTS: 23

Kidney Hypertrophy malady

Summaries for Kidney Hypertrophy

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32MalaCards
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MalaCards: Kidney Hypertrophy, also known as hypertrophy of kidney, is related to hypertension and glomerulonephritis. An important gene associated with Kidney Hypertrophy is TGFB1 (transforming growth factor, beta 1), and among its related pathways are Integrated Pancreatic Cancer Pathway and Endocytosis. Affiliated tissues include kidney, bone and liver.

Aliases & Classifications for Kidney Hypertrophy

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT
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Aliases & Descriptions:

kidney hypertrophy 8 10
hypertrophy of kidney 60


External Ids:

Disease Ontology8 DOID:9622
SNOMED-CT56 197800004, 88531004
ICD9CM27 593.1

Related Diseases for Kidney Hypertrophy

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Kidney Hypertrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hypertension10.2
2glomerulonephritis10.0TGFB1
3bronchopneumonia10.0
4arteriosclerosis10.0
5chronic kidney failure10.0
6chronic pyelonephritis10.0
7proteinuria10.0
8pyelonephritis10.0
9uremia10.0

Graphical network of diseases related to Kidney Hypertrophy:



Diseases related to kidney hypertrophy

Clinical Features for Kidney Hypertrophy

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Drugs & Therapeutics for Kidney Hypertrophy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Kidney Hypertrophy

Search CenterWatch for Kidney Hypertrophy

Genetic Tests for Kidney Hypertrophy

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Anatomical Context for Kidney Hypertrophy

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32MalaCards
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MalaCards organs/tissues related to Kidney Hypertrophy:

32
Kidney, Bone, Liver, Brain, Prostate

Animal Models for Kidney Hypertrophy or affiliated genes

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Publications for Kidney Hypertrophy

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50PubMed
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Articles related to Kidney Hypertrophy:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease. (24028070)
2014
2
Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease. (21242674)
2011
3
Plasma adiponectin concentration and left ventricular hypertrophy in kidney transplant patients. (20964715)
2011
4
Fibroblast growth factor 23 in chronic kidney disease: bridging the gap between bone mineral metabolism and left ventricular hypertrophy. (21135546)
2011
5
A comparison of the effects of ramipril and losartan on blood pressure control and left ventricle hypertrophy in patients with autosomal dominant polycystic kidney disease. (20722556)
2010
6
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats. (20404054)
2010
7
Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis. (19211686)
2009
8
The relationship between insulin resistance and left ventricular hypertrophy in patients with early chronic kidney disease.]. (20193515)
2009
9
Is valvular calcification a part of the missing link between residual kidney function and cardiac hypertrophy in peritoneal dialysis patients? (19713292)
2009
10
Left ventricular hypertrophy in mild and moderate reduction in kidney function determined using cardiac magnetic resonance imaging and cystatin C: the multi-ethnic study of atherosclerosis (MESA). (18845370)
2008
11
Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension. (18423813)
2008
12
Epoetin alfa and darbepoetin alfa: effects on ventricular hypertrophy in patients with chronic kidney disease. (18651544)
2008
13
Effect of sirolimus on left ventricular hypertrophy in kidney transplant recipients: a 1-year nonrandomized controlled trial. (18585837)
2008
14
Left ventricular hypertrophy in predialysis chronic kidney disease: impact of cardiomuscular stress markers]. (18186229)
2007
15
Relationship of brain natriuretic peptide to renal function and left ventricular hypertrophy in patients with chronic kidney disease]. (18396626)
2007
16
Risk factors and pathogenetic mechanisms of left ventricular hypertrophy in progressive chronic kidney disease and after transplantation of the kidney]. (17684964)
2007
17
Association between biomarkers of inflammation and left ventricular hypertrophy in moderate chronic kidney disease. (17474556)
2007
18
Development of hypertension and kidney hypertrophy in transgenic mice overexpressing ARAP1 gene in the kidney. (16801480)
2006
19
Renin-angiotensin system blockade prevents the increase in plasma transforming growth factor beta 1, and reduces proteinuria and kidney hypertrophy in the streptozotocin-diabetic rat. (15526251)
2004
20
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. Part II--Kidney hypertrophy and calcium deposition. (15161952)
2004
21
Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to heparin. (15126919)
2004
22
The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption II--kidney hypertrophy, vitellogenin and spiggin induction. (15588642)
2004
23
No effect of angiotensin-converting enzyme gene polymorphism on disease progression and left ventricular hypertrophy in autosomal dominant polycystic kidney disease. (14600431)
2003
24
Left ventricular hypertrophy in hypertensive patients with autosomal dominant polycystic kidney disease: influence of blood pressure and humoral and neurohormonal factors. (10878400)
2000
25
Reversal of left ventricular hypertrophy with angiotensin converting enzyme inhibition in hypertensive patients with autosomal dominant polycystic kidney disease. (10344347)
1999
26
The effect of angiotensin-converting enzyme inhibitors on left ventricular hypertrophy in patients with chronic glomerulonephritis and pronounced kidney failure]. (9297267)
1997
27
Isthmus hypertrophy mimics tumour in horseshoe kidney: a case report. (8713567)
1996
28
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. (8603776)
1996
29
An evaluation of the role of polyamines in different models of kidney hypertrophy in mice. (7474658)
1995
30
Inhibition of renal ornithine decarboxylase activity fails to reduce kidney size and urinary albumin excretion in diabetic rats with manifest kidney hypertrophy. (7796931)
1995
31
Antihypertensive effect of sesamin. II. Protection against two-kidney, one-clip renal hypertension and cardiovascular hypertrophy. (8845824)
1995
32
Renal proteinases and kidney hypertrophy in experimental diabetes. (7926340)
1994
33
Inhibition of renal ornithine decarboxylase activity prevents kidney hypertrophy in experimental diabetes. (8447376)
1993
34
Morphometric analysis of kidney hypertrophy in rats after chronic potassium depletion. (1566879)
1992
35
Transient increase in renal insulin-like growth factor binding proteins during initial kidney hypertrophy in experimental diabetes in rats. (1377139)
1992
36
Kidney IGF-I and renal hypertrophy in GH-deficient diabetic dwarf rats. (1616029)
1992
37
Increased ornithine decarboxylase activity in kidneys undergoing hypertrophy in experimental diabetes. (1511780)
1992
38
Vasopressin-dependent kidney hypertrophy: role of urinary concentration in protein-induced hypertrophy and in the progression of chronic renal failure. (2042645)
1991
39
Medullary sponge kidney and congenital hemi-hypertrophy. (3408897)
1988
40
Characterization of beta-adrenergic receptor subtypes in androgen-induced mouse kidney hypertrophy using a new high-affinity ligand, [125I]iodocyanopindolol. (6299377)
1983
41
Increased beta-adrenergic receptor complement in androgen-induced mouse kidney hypertrophy. (6269651)
1981
42
Regulation of compensatory kidney hypertrophy by its own products. (894611)
1977
43
The influence of salt intake on glomerular count in compensatory kidney hypertrophy in rats of different ages. (954972)
1976
44
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy. (4119904)
1972
45
Immunochemical studies on kidney hypertrophy of the rat. (13954727)
1962
46
On renal failure complicating surgical diseases (laparotomy etc.), with special regard to conservative treatment, and the need for the artificial kidney (dialyser, ultrafilter) in rational renal therapy; acute tubular nephritis, chronic pyelonephritis and prostatic hypertrophy with urinary retention. (14398036)
1954
47
Clinico-pathological conference: hypoplasia of the kidneys secondary to chronic pyelonephritis; acute bronchitis; myocardial hypertrophy; fatty metamorphosis of the liver; rickets. (14870327)
1951
48
WEEKLY clinicopathological exercises: chronic pyelonephritis severe (with uremia); atrophy of the right kidney, hypertrophy of left; bronchopneumonia; aortic arteriosclerosis, severe, ascending arch, with short localized dissection; calcareous aortic stenosis. (14863577)
1951
49
THE PRODUCTION OF HYPERTENSION BY THE PREVENTION OF KIDNEY HYPERTROPHY: (Preliminary Report). (20321520)
1939
50
Congenital Hydronephrosis of both Kidneys; both Ureters dilated, with Hypertrophy of Bladder. (19979448)
1916

Genetic Variations for Kidney Hypertrophy

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Expression for genes affiliated with Kidney Hypertrophy

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Kidney Hypertrophy

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Pathways for genes affiliated with Kidney Hypertrophy

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37NCBI BioSystems Database, 29KEGG
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Pathways related to Kidney Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4TGFB1, POLR1A
29.1TGFB1, ARAP1

Compounds for genes affiliated with Kidney Hypertrophy

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GO Terms for genes affiliated with Kidney Hypertrophy

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Products for genes affiliated with Kidney Hypertrophy

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  • Antibodies
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Sources for Kidney Hypertrophy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet