MCID: KDN013
MIFTS: 19

Kidney Hypertrophy malady

Nephrological diseases category
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Summaries for Kidney Hypertrophy

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33MalaCards
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MalaCards: Kidney Hypertrophy, also known as hypertrophy of kidney, is related to hypertension and bronchopneumonia. An important gene associated with Kidney Hypertrophy is TGFB1 (transforming growth factor, beta 1), and among its related pathways are GPCR Pathway and Integrated Pancreatic Cancer Pathway. Affiliated tissues include kidney.

Aliases & Classifications for Kidney Hypertrophy

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

kidney hypertrophy 8 10
hypertrophy of kidney 62


External Ids:

Disease Ontology8 DOID:9622
SNOMED-CT58 197800004, 88531004
ICD9CM27 593.1

Related Diseases for Kidney Hypertrophy

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17GeneCards, 18GeneDecks
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Diseases related to Kidney Hypertrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hypertension10.2
2bronchopneumonia10.0
3arteriosclerosis10.0
4chronic pyelonephritis10.0
5proteinuria10.0
6pyelonephritis10.0
7uremia10.0

Graphical network of diseases related to Kidney Hypertrophy:



Diseases related to kidney hypertrophy

Symptoms for Kidney Hypertrophy

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Drugs & Therapeutics for Kidney Hypertrophy

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Kidney Hypertrophy

Search NIH Clinical Center for Kidney Hypertrophy

Genetic Tests for Kidney Hypertrophy

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Anatomical Context for Kidney Hypertrophy

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33MalaCards
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MalaCards organs/tissues related to Kidney Hypertrophy:

33
Kidney

Animal Models for Kidney Hypertrophy or affiliated genes

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Publications for Kidney Hypertrophy

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52PubMed
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Articles related to Kidney Hypertrophy:

(show all 22)
idTitleAuthorsYear
1
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats. (20404054)
2010
2
Development of hypertension and kidney hypertrophy in transgenic mice overexpressing ARAP1 gene in the kidney. (16801480)
2006
3
Renin-angiotensin system blockade prevents the increase in plasma transforming growth factor beta 1, and reduces proteinuria and kidney hypertrophy in the streptozotocin-diabetic rat. (15526251)
2004
4
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. Part II--Kidney hypertrophy and calcium deposition. (15161952)
2004
5
The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption II--kidney hypertrophy, vitellogenin and spiggin induction. (15588642)
2004
6
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. (8603776)
1996
7
An evaluation of the role of polyamines in different models of kidney hypertrophy in mice. (7474658)
1995
8
Inhibition of renal ornithine decarboxylase activity fails to reduce kidney size and urinary albumin excretion in diabetic rats with manifest kidney hypertrophy. (7796931)
1995
9
Renal proteinases and kidney hypertrophy in experimental diabetes. (7926340)
1994
10
Inhibition of renal ornithine decarboxylase activity prevents kidney hypertrophy in experimental diabetes. (8447376)
1993
11
Morphometric analysis of kidney hypertrophy in rats after chronic potassium depletion. (1566879)
1992
12
Transient increase in renal insulin-like growth factor binding proteins during initial kidney hypertrophy in experimental diabetes in rats. (1377139)
1992
13
Vasopressin-dependent kidney hypertrophy: role of urinary concentration in protein-induced hypertrophy and in the progression of chronic renal failure. (2042645)
1991
14
Characterization of beta-adrenergic receptor subtypes in androgen-induced mouse kidney hypertrophy using a new high-affinity ligand, [125I]iodocyanopindolol. (6299377)
1983
15
Increased beta-adrenergic receptor complement in androgen-induced mouse kidney hypertrophy. (6269651)
1981
16
Regulation of compensatory kidney hypertrophy by its own products. (894611)
1977
17
The influence of salt intake on glomerular count in compensatory kidney hypertrophy in rats of different ages. (954972)
1976
18
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy. (4119904)
1972
19
Immunochemical studies on kidney hypertrophy of the rat. (13954727)
1962
20
WEEKLY clinicopathological exercises: chronic pyelonephritis severe (with uremia); atrophy of the right kidney, hypertrophy of left; bronchopneumonia; aortic arteriosclerosis, severe, ascending arch, with short localized dissection; calcareous aortic stenosis. (14863577)
1951
21
Kidney hypertrophy in B complex deficiency. (21024173)
1946
22
THE PRODUCTION OF HYPERTENSION BY THE PREVENTION OF KIDNEY HYPERTROPHY: (Preliminary Report). (20321520)
1939

Variations for Kidney Hypertrophy

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Expression for genes affiliated with Kidney Hypertrophy

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Kidney Hypertrophy

Search GEO for disease gene expression data for Kidney Hypertrophy.

Pathways for genes affiliated with Kidney Hypertrophy

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Sources:
50PathCards, 53QIAGEN, 38NCBI BioSystems Database
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Pathways related to Kidney Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1POLR1A, TGFB1
29.1POLR1A, TGFB1

Compounds for genes affiliated with Kidney Hypertrophy

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GO Terms for genes affiliated with Kidney Hypertrophy

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Products for genes affiliated with Kidney Hypertrophy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Kidney Hypertrophy

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet