MCID: KDN013
MIFTS: 19

Kidney Hypertrophy malady

Nephrological diseases category

Summaries for Kidney Hypertrophy

About this section
Sources:
34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
MalaCards: Kidney Hypertrophy, also known as hypertrophy of kidney, is related to hypertension and bronchopneumonia. An important gene associated with Kidney Hypertrophy is TGFB1 (transforming growth factor, beta 1), and among its related pathways are GPCR Pathway and Integrated Pancreatic Cancer Pathway. Affiliated tissues include kidney.

Aliases & Classifications for Kidney Hypertrophy

About this section
Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 28ICD9CM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

kidney hypertrophy 9 11
hypertrophy of kidney 63


External Ids:

Disease Ontology9 DOID:9622
SNOMED-CT59 197800004, 88531004
ICD9CM28 593.1

Related Diseases for Kidney Hypertrophy

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases related to Kidney Hypertrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hypertension10.2
2bronchopneumonia10.0
3arteriosclerosis10.0
4chronic pyelonephritis10.0
5proteinuria10.0
6pyelonephritis10.0
7uremia10.0

Graphical network of diseases related to Kidney Hypertrophy:



Diseases related to kidney hypertrophy

Symptoms for Kidney Hypertrophy

About this section

Drugs & Therapeutics for Kidney Hypertrophy

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Kidney Hypertrophy

Drug clinical trials:

Search ClinicalTrials for Kidney Hypertrophy

Search NIH Clinical Center for Kidney Hypertrophy

Search CenterWatch for Kidney Hypertrophy

Genetic Tests for Kidney Hypertrophy

About this section

Anatomical Context for Kidney Hypertrophy

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Kidney Hypertrophy:

34
Kidney

Animal Models for Kidney Hypertrophy or affiliated genes

About this section

Publications for Kidney Hypertrophy

About this section
Sources:
53PubMed
See all sources

Articles related to Kidney Hypertrophy:

(show all 22)
idTitleAuthorsYear
1
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats. (20404054)
2010
2
Development of hypertension and kidney hypertrophy in transgenic mice overexpressing ARAP1 gene in the kidney. (16801480)
2006
3
Renin-angiotensin system blockade prevents the increase in plasma transforming growth factor beta 1, and reduces proteinuria and kidney hypertrophy in the streptozotocin-diabetic rat. (15526251)
2004
4
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. Part II--Kidney hypertrophy and calcium deposition. (15161952)
2004
5
The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption II--kidney hypertrophy, vitellogenin and spiggin induction. (15588642)
2004
6
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. (8603776)
1996
7
An evaluation of the role of polyamines in different models of kidney hypertrophy in mice. (7474658)
1995
8
Inhibition of renal ornithine decarboxylase activity fails to reduce kidney size and urinary albumin excretion in diabetic rats with manifest kidney hypertrophy. (7796931)
1995
9
Renal proteinases and kidney hypertrophy in experimental diabetes. (7926340)
1994
10
Inhibition of renal ornithine decarboxylase activity prevents kidney hypertrophy in experimental diabetes. (8447376)
1993
11
Morphometric analysis of kidney hypertrophy in rats after chronic potassium depletion. (1566879)
1992
12
Transient increase in renal insulin-like growth factor binding proteins during initial kidney hypertrophy in experimental diabetes in rats. (1377139)
1992
13
Vasopressin-dependent kidney hypertrophy: role of urinary concentration in protein-induced hypertrophy and in the progression of chronic renal failure. (2042645)
1991
14
Characterization of beta-adrenergic receptor subtypes in androgen-induced mouse kidney hypertrophy using a new high-affinity ligand, [125I]iodocyanopindolol. (6299377)
1983
15
Increased beta-adrenergic receptor complement in androgen-induced mouse kidney hypertrophy. (6269651)
1981
16
Regulation of compensatory kidney hypertrophy by its own products. (894611)
1977
17
The influence of salt intake on glomerular count in compensatory kidney hypertrophy in rats of different ages. (954972)
1976
18
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy. (4119904)
1972
19
Immunochemical studies on kidney hypertrophy of the rat. (13954727)
1962
20
WEEKLY clinicopathological exercises: chronic pyelonephritis severe (with uremia); atrophy of the right kidney, hypertrophy of left; bronchopneumonia; aortic arteriosclerosis, severe, ascending arch, with short localized dissection; calcareous aortic stenosis. (14863577)
1951
21
Kidney hypertrophy in B complex deficiency. (21024173)
1946
22
THE PRODUCTION OF HYPERTENSION BY THE PREVENTION OF KIDNEY HYPERTROPHY: (Preliminary Report). (20321520)
1939

Variations for Kidney Hypertrophy

About this section

Expression for genes affiliated with Kidney Hypertrophy

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Kidney Hypertrophy

Search GEO for disease gene expression data for Kidney Hypertrophy.

Pathways for genes affiliated with Kidney Hypertrophy

About this section
Sources:
51PathCards, 54QIAGEN, 39NCBI BioSystems Database
See all sources

Pathways related to Kidney Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1POLR1A, TGFB1
29.1POLR1A, TGFB1

Compounds for genes affiliated with Kidney Hypertrophy

About this section

GO Terms for genes affiliated with Kidney Hypertrophy

About this section

Products for genes affiliated with Kidney Hypertrophy

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Kidney Hypertrophy

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet