MCID: KDN006
MIFTS: 24

Kidney Papillary Necrosis

Categories: Nephrological diseases

Aliases & Classifications for Kidney Papillary Necrosis

MalaCards integrated aliases for Kidney Papillary Necrosis:

Name: Kidney Papillary Necrosis 12 42 14 69
Necrotizing Renal Papillitis 12
Renal Papillitis Necrotizing 12
Papillary Necrosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2981
MeSH 42 D007681
SNOMED-CT 64 197651008 90241004
UMLS 69 C0022667

Summaries for Kidney Papillary Necrosis

MalaCards based summary : Kidney Papillary Necrosis, also known as necrotizing renal papillitis, is related to immune-complex glomerulonephritis and glycogen storage disease viii. An important gene associated with Kidney Papillary Necrosis is LYZ (Lysozyme), and among its related pathways/superpathways are Platelet activation and Celecoxib Pathway, Pharmacodynamics. Affiliated tissues include kidney, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 72 Renal papillary necrosis is a form of nephropathy involving the necrosis of the renal papilla. Lesions... more...

Related Diseases for Kidney Papillary Necrosis

Diseases related to Kidney Papillary Necrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
id Related Disease Score Top Affiliating Genes
1 immune-complex glomerulonephritis 10.3 ALB LYZ
2 glycogen storage disease viii 10.3 LYZ REN
3 eustachian tube disease 10.3 LYZ REN
4 toxic myocarditis 10.2 ALB LYZ
5 wernicke-korsakoff syndrome 10.2 ALB REN
6 non-congenital cyst of kidney 10.2 ALB REN
7 adenocarcinoma 10.2 ALB REN
8 myopia 10.1 ALB REN
9 broad ligament malignant neoplasm 10.1 ALB REN
10 capillary hemangioma 10.1 ALB REN
11 cystinosis 10.1 ALB REN
12 acute liver failure 10.1 ALB REN
13 chronic inflammatory demyelinating polyradiculoneuropathy 10.1 ALB REN
14 pulmonary embolism 10.0 ALB LYZ
15 ovarian hyperstimulation syndrome 10.0 ALB REN
16 paranasal sinus sarcoma 10.0 ALB REN
17 prostate neuroendocrine neoplasm 10.0 ALB REN
18 hypertrichosis 10.0 ALB REN
19 survival motor neuron spinal muscular atrophy 9.9 ALB REN
20 pulmonary artery hypoplasia 9.8 PTGS1 REN
21 bardet-biedl syndrome 17 9.8 ALB PTGS1
22 chronic myelomonocytic leukemia 9.8 ALB REN
23 waterhouse-friderichsen syndrome 9.8
24 calcinosis 9.8 ALB LYZ REN
25 ureteral obstruction 9.7
26 pleural tuberculosis 9.7 ALB REN
27 anuria 9.6
28 cervix uteri carcinoma in situ 9.5 ALB REN
29 glomerulonephritis 9.5
30 nephropathia epidemica 9.5
31 interstitial nephritis 9.5
32 chronic pyelonephritis 9.5
33 hydronephrosis 9.5
34 pyelonephritis 9.5
35 leptospirosis 9.5
36 hemoglobinopathy 9.5
37 protein c deficiency 9.5
38 rapidly progressive glomerulonephritis 9.5
39 medullary sponge kidney 9.5
40 myocardial infarction 9.0 ALB PTGS1 REN
41 iga glomerulonephritis 7.9 ALB LYZ NFAT5 PTGIR PTGS1 REN

Graphical network of the top 20 diseases related to Kidney Papillary Necrosis:



Diseases related to Kidney Papillary Necrosis

Symptoms & Phenotypes for Kidney Papillary Necrosis

MGI Mouse Phenotypes related to Kidney Papillary Necrosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 PTGS1 REN ALB LYZ NFAT5 PTGIR
2 cardiovascular system MP:0005385 9.83 LYZ NFAT5 PTGIR PTGS1 REN
3 hematopoietic system MP:0005397 9.8 LYZ NFAT5 PTGIR PTGS1 REN
4 mortality/aging MP:0010768 9.73 ALB LYZ NFAT5 PTGIR PTGS1 REN
5 immune system MP:0005387 9.72 LYZ NFAT5 PTGIR PTGS1 REN
6 muscle MP:0005369 9.46 ALB NFAT5 PTGS1 REN
7 neoplasm MP:0002006 9.26 ALB LYZ PTGIR PTGS1
8 renal/urinary system MP:0005367 9.02 ALB LYZ NFAT5 PTGS1 REN

Drugs & Therapeutics for Kidney Papillary Necrosis

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Regional and Long Term Outcomes of Acute Kidney Injury in England From 2000 to 2015 - A National Database Study Completed NCT02675296

Search NIH Clinical Center for Kidney Papillary Necrosis

Cochrane evidence based reviews: kidney papillary necrosis

Genetic Tests for Kidney Papillary Necrosis

Anatomical Context for Kidney Papillary Necrosis

MalaCards organs/tissues related to Kidney Papillary Necrosis:

39
Kidney

Publications for Kidney Papillary Necrosis

Variations for Kidney Papillary Necrosis

Expression for Kidney Papillary Necrosis

Search GEO for disease gene expression data for Kidney Papillary Necrosis.

Pathways for Kidney Papillary Necrosis

Pathways related to Kidney Papillary Necrosis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.41 PTGIR PTGS1
2 11.02 PTGIR PTGS1
3 10.86 PTGIR PTGS1
4 10.43 PTGIR PTGS1
5 10.07 PTGIR PTGS1

GO Terms for Kidney Papillary Necrosis

Biological processes related to Kidney Papillary Necrosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular oxidant detoxification GO:0098869 9.16 ALB PTGS1
2 regulation of blood pressure GO:0008217 8.96 PTGS1 REN
3 retina homeostasis GO:0001895 8.62 ALB LYZ

Sources for Kidney Papillary Necrosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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