MCID: KMR001
MIFTS: 50

Kimura Disease

Categories: Rare diseases, Bone diseases, Skin diseases, Immune diseases

Aliases & Classifications for Kimura Disease

MalaCards integrated aliases for Kimura Disease:

Name: Kimura Disease 12 50 56 52 14 69
Angiolymphoid Hyperplasia with Eosinophilia 50
Eosinophilic Hyperplastic Lymphogranuloma 50
Eosinophilic Lymphofollicular Granuloma 50
Eosinophilic Granuloma of Soft Tissue 50
Eosinophilic Lymphofolliculosis 50
Eosinophilic Lymphogranuloma 56
Kimura's Disease 12

Characteristics:

Orphanet epidemiological data:

56
kimura disease
Prevalence: <1/1000000 (Worldwide); Age of onset: Adult; Age of death: normal life expectancy;

Classifications:



External Ids:

Disease Ontology 12 DOID:7365
MeSH 42 D000796
NCIt 47 C26867
Orphanet 56 ORPHA482
MESH via Orphanet 43 D000796
UMLS via Orphanet 70 C0033838
ICD10 via Orphanet 34 I89.8
SNOMED-CT via HPO 65 10890000
UMLS 69 C0033838

Summaries for Kimura Disease

NIH Rare Diseases : 50 kimura disease is a rare, benign, chronic disorder that causes inflammation of tissue (nodules) under the skin of the head or neck.  these nodules tend to recur despite treatment. the cause of this condition is unknown, but may be due to an immune response. last updated: 1/20/2011

MalaCards based summary : Kimura Disease, also known as angiolymphoid hyperplasia with eosinophilia, is related to histiocytoid hemangioma and skin epithelioid hemangioma, and has symptoms including eosinophilia, follicular hyperplasia and increased ige level. An important gene associated with Kimura Disease is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Rivaroxaban and Pitavastatin have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and heart, and related phenotypes are hematopoietic system and immune system

Related Diseases for Kimura Disease

Diseases related to Kimura Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
id Related Disease Score Top Affiliating Genes
1 histiocytoid hemangioma 11.5
2 skin epithelioid hemangioma 11.2
3 papillary follicular thyroid adenocarcinoma 10.6 IL5 RNASE3
4 toxic diffuse goiter 10.6 IL5 RNASE3
5 crustacean allergy 10.6 IL5 RNASE3
6 subacute bacterial endocarditis 10.5 IL5 RNASE3
7 orbit alveolar rhabdomyosarcoma 10.5 IL4 IL5
8 angioid streaks of choroid 10.5 IL4 IL5
9 allescheriosis 10.5 IL4 IL5
10 urethral intrinsic sphincter deficiency 10.5 IL4 IL5
11 cherry allergy 10.5 IL4 IL5
12 signet ring cell adenocarcinoma 10.5 IL5 RNASE3
13 penis agenesis 10.5 CCL11 IL5
14 skin disease 10.5 IL5 RNASE3
15 solitary cyst of breast 10.5 CCL11 IL5
16 histoplasmosis retinitis 10.5 IL4 IL5
17 abdominal tuberculosis 10.5 IL4 IL5
18 hypothyroidism due to deficient transcription factors involved in pituitary development or function 10.5 IL4 IL5
19 glucose intolerance 10.5 IL4 IL5
20 autoimmune neuropathy 10.5 IL5 RNASE3
21 cholesteatoma of middle ear 10.5 CCL11 IL5
22 whistling face syndrome, recessive form 10.5 IL5 RNASE3
23 philophthalmiasis 10.5 IL4 IL5
24 hypercementosis 10.4 CCL5 IL5
25 spindle cell variant squamous cell breast carcinoma 10.4 IL4 IL5
26 psychotic disorder 10.4 CCL11 IL4
27 glioblastoma multiforme 10.4 IL5 RNASE3
28 dissociated nystagmus 10.4 IL4 IL5
29 retinal vascular disease 10.4 CCL11 IL4
30 vulvar disease 10.4 CCL5 RNASE3
31 chronic cholangitis 10.4 CCL11 IL4
32 loiasis 10.4 IL4 IL5
33 hemangioma 10.3
34 hidradenitis suppurativa 10.3 CCL11 CCL5
35 epidermolysis bullosa simplex superficialis 10.3 IL4 RNASE3
36 abnormal retinal correspondence 10.3 IL4 IL5
37 dermatitis herpetiformis 10.3 CCL5 IL5
38 vascular dementia 10.3 CCL5 IL4
39 central nervous system origin vertigo 10.3 IL4 RNASE3
40 gonococcal endophthalmia 10.2 CCL5 IL5
41 marasmus 10.2 IL4 IL5 RNASE3
42 x-linked intellectual disability, van esch type 10.2 IL4 IL5 RNASE3
43 orbital plasma cell granuloma 10.2 IL4 IL5 RNASE3
44 winchester syndrome 10.2 IL4 IL5 RNASE3
45 purpura fulminans 10.2 IL4 IL5 RNASE3
46 subcorneal pustular dermatosis 10.2 CCL11 IL4
47 acute gonococcal prostatitis 10.2 IL4 IL5 RNASE3
48 nut allergy 10.2 IL4 IL5 RNASE3
49 sublingual gland cancer 10.2 IL4 IL5 RNASE3
50 balkan nephropathy 10.2 IL4 IL5 RNASE3

Graphical network of the top 20 diseases related to Kimura Disease:



Diseases related to Kimura Disease

Symptoms & Phenotypes for Kimura Disease

Human phenotypes related to Kimura Disease:

56 32
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 eosinophilia 56 32 hallmark (90%) Very frequent (99-80%) HP:0001880
2 follicular hyperplasia 56 32 hallmark (90%) Very frequent (99-80%) HP:0002729
3 increased ige level 56 32 hallmark (90%) Very frequent (99-80%) HP:0003212
4 abnormality of the salivary glands 56 32 occasional (7.5%) Occasional (29-5%) HP:0010286
5 lymphadenopathy 56 Frequent (79-30%)

MGI Mouse Phenotypes related to Kimura Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CCL11 CCL5 CCR3 IL33 IL4 IL5
2 immune system MP:0005387 9.5 CCL11 CCL5 CCR3 IL33 IL4 IL5
3 respiratory system MP:0005388 9.1 IL4 IL5 TSLP CCL11 CCR3 IL33

Drugs & Therapeutics for Kimura Disease

Drugs for Kimura Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rivaroxaban Approved Phase 4 366789-02-8
2
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
3
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
4
Ticlopidine Approved Phase 4 55142-85-3 5472
5
Everolimus Approved Phase 4 159351-69-6 6442177
6
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
7
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
8
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
9
Apixaban Approved Phase 4 503612-47-3 10182969
10 Edoxaban Approved Phase 4 480449-70-5
11
Warfarin Approved Phase 4 81-81-2 6691 54678486
12
Losartan Approved Phase 4 114798-26-4 3961
13
Clopidogrel Approved, Nutraceutical Phase 4 120202-66-6, 113665-84-2 60606
14
Angiotensin II Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
15 Anticoagulants Phase 4
16 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
17 Antithrombin III Phase 4
18 Antithrombins Phase 4
19 Dabigatran Phase 4
20 Factor Xa Inhibitors Phase 4
21 HIV Protease Inhibitors Phase 4
22
protease inhibitors Phase 4
23 Serine Proteinase Inhibitors Phase 4
24 Anticholesteremic Agents Phase 4
25 Antimetabolites Phase 4
26 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
27 Hypolipidemic Agents Phase 4
28 Lipid Regulating Agents Phase 4
29 Adrenergic beta-Antagonists Phase 4,Phase 1
30 Angiotensin II Type 1 Receptor Blockers Phase 4
31 Angiotensin Receptor Antagonists Phase 4
32 Angiotensin-Converting Enzyme Inhibitors Phase 4
33 Angiotensinogen Phase 4
34 Antihypertensive Agents Phase 4
35 calcium channel blockers Phase 4,Phase 3
36 Calcium, Dietary Phase 4,Phase 3
37 diuretics Phase 4
38 Cytochrome P-450 Enzyme Inhibitors Phase 4
39 Fibrinolytic Agents Phase 4
40 Neurotransmitter Agents Phase 4,Phase 1
41 Platelet Aggregation Inhibitors Phase 4
42 Purinergic P2 Receptor Antagonists Phase 4
43 Purinergic P2Y Receptor Antagonists Phase 4
44 Anti-Bacterial Agents Phase 4
45 Antibiotics, Antitubercular Phase 4
46 Antifungal Agents Phase 4
47 Anti-Infective Agents Phase 4
48 Immunosuppressive Agents Phase 4,Phase 3,Phase 1
49 Atorvastatin Calcium Phase 4 134523-03-8
50 Analgesics Phase 4,Phase 3,Phase 1

Interventional clinical trials:

(show all 34)

id Name Status NCT ID Phase Drugs
1 Anti-inflammatory Effects of Rivaroxaban Versus Dabigatran Unknown status NCT02331602 Phase 4 Rivaroxaban;Dabigatran
2 Kanagawa Valsartan Trial (KVT): Effects of Valsartan on Renal and Cardiovascular Disease Completed NCT00190580 Phase 4 valsartan;Conventional antihypertensive drugs
3 Clopidogrel High Dose Evaluation for the Patient With Coronary Artery Disease in Japan Completed NCT01069302 Phase 4 Clopidogrel;Clopidogrel;Clopidogrel;Clopidogrel
4 Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial Completed NCT01123291 Phase 4
5 Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting Stent Trial Completed NCT01035450 Phase 4
6 Short and Optimal Duration of Dual Antiplatelet Therapy Study Completed NCT01659034 Phase 4 Thienopyridine for 3 months
7 NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-eluting Stent Trial Completed NCT01303640 Phase 4
8 Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS) Completed NCT00242944 Phase 4 Pitavastatin;Atorvastatin
9 Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure Completed NCT00733161 Phase 4
10 The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study) Completed NCT00250380 Phase 4
11 ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study Recruiting NCT02619760 Phase 4 1-month DAPT;12-month DAPT
12 The Preventive Coronary Intervention on Stenosis With Functionally Insignificant Vulnerable Plaque Recruiting NCT02316886 Phase 4 Optimal Medical treatment
13 Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study Active, not recruiting NCT01962545 Phase 4 OAC alone
14 Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound Terminated NCT01230216 Phase 4 control systolic blood pressure less than 120 mmHg;control systolic blood pressure less than 140 mmHg
15 Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants Completed NCT00419146 Phase 2, Phase 3 Ethyl-eicosapentaenoic acid (EPA);Vitamins E + C
16 A Study of Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3) Completed NCT00912093 Phase 3 Icatibant;Placebo
17 An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain Completed NCT01202227 Phase 3 pregabalin
18 Aromatase Inhibitors or GnRH-a for Uterine Adenomyosis Completed NCT01218581 Phase 2, Phase 3 received oral letrozole (2.5 mg/day)and goserelin subcutaneosly (3.6 mg/month)
19 A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema Completed NCT01100307 Phase 3 pegaptanib sodium
20 Study of Cetuximab With Concomitant-boost Radiotherapy in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) Completed NCT00865098 Phase 2 Cetuximab
21 Low Intensity Physical Activity Leads to Improvement in Brachial-ankle Pulse Wave Velocity of Hemiplegics Completed NCT01569386 Phase 2
22 Neoadjuvant Nab-PTX and Trastuzumab for ER Negative and HER2 Positive Breast Cancer Recruiting NCT02598310 Phase 2 nab-paclitaxel;Trastuzumab
23 Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers Completed NCT02045264 Phase 1 Icatibant (30 mg)
24 An Open Label, Single Arm, Dose Escalation Phase 1 Trial of PRI-724 in Patients With HCV-induced Cirrhosis Completed NCT02195440 Phase 1 PRI-724
25 Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy With Pitavastatin in Coronary Artery Disease (REAL-CAD) Unknown status NCT01042730 Pitavastatin 1 mg daily or 4 mg daily
26 Epithelioid Hemangioma of Bone And Soft Tissue Completed NCT03169595
27 A Study of Duration of Maintained Efficacy in Rheumatoid Arthritis (RA) Patients Off Treatment With MRA(a Development Code of Tocilizumab, an Anti IL-6 Receptor Monoclonal Antibody.) Completed NCT00661284
28 Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry Recruiting NCT02418442
29 Start Time Optimization of Biologics in Polyarticular JIA Recruiting NCT02593006
30 Kyoto Congestive Heart Failure Study Recruiting NCT02334891
31 AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorb™ BVS) in Japanese Population Active, not recruiting NCT01844284
32 Special Investigation in Patients With Ulcerative Colitis Active, not recruiting NCT01947816
33 A Follow-up Evaluation Study of PRI-724-1101 Active, not recruiting NCT02828254 PRI-724
34 Individualized Management for Long Gap Esophageal Atresia Not yet recruiting NCT03023865

Search NIH Clinical Center for Kimura Disease

Genetic Tests for Kimura Disease

Anatomical Context for Kimura Disease

MalaCards organs/tissues related to Kimura Disease:

39
Skin, Bone, Heart, Lymph Node, Breast, Salivary Gland, Endothelial

Publications for Kimura Disease

Articles related to Kimura Disease:

(show top 50) (show all 99)
id Title Authors Year
1
Superficial Parotidectomy Plane for Debulking Surgery in Kimura Disease. ( 28468187 )
2017
2
Expression of the interleukin-21 and phosphorylated extracellular signal regulated kinase 1/2 in Kimura disease. ( 28108473 )
2017
3
Superficial Parotidectomy Plane for Debulking Surgery in Kimura Disease. ( 28106687 )
2017
4
Treatment of Kimura disease with mycophenolate mofetil monotherapy. ( 28932783 )
2017
5
A Rare Case of Kimura Disease with Bilateral Parotid Involvement. ( 28946727 )
2017
6
Kimura Disease of the Breast - A Previously Undescribed Entity. ( 27058987 )
2016
7
Kimura disease as mimicker of lymphoma - A case report. ( 27728556 )
2016
8
Kimura Disease Presenting as Forehead Soft Mass. ( 27100647 )
2016
9
An Unusual Clinical Presentation of Kimura Disease Manifesting with a Typical Cephalocervical Lesion and an Atypical Subcutaneous Hip Mass Lesion. ( 27086824 )
2016
10
Comparison of Local Recurrence Rate of Three Treatment Modalities for Kimura Disease. ( 26674917 )
2016
11
Kimura disease in a Maori man with nephrotic syndrome. ( 27981775 )
2016
12
Kimura disease. No age or ethnicity limit. ( 26905356 )
2016
13
Eosinophilia and multiple lymphadenopathy: Kimura disease, a rare, but benign condition. ( 27581232 )
2016
14
Concurrent Kimura disease and lupus nephritis: A case report. ( 27741124 )
2016
15
A case of refractory Kimura disease with a buccal bulky mass successfullyA treated with low-dose cyclosporine A: Report andA reviewA ofA the literature. ( 26666475 )
2016
16
Human Polyomavirus-6 Infecting Lymph Nodes of a Patient With an Angiolymphoid Hyperplasia With Eosinophilia or Kimura Disease. ( 26962076 )
2016
17
Pulmonary embolism as the initial clinical presentation of Kimura disease: case report and literature review. ( 25699606 )
2015
18
Recurrent Kimura Disease of the Inner Canthus With No Lymphadenopathy. ( 26020715 )
2015
19
A mass under parotid gland: a patient with kimura disease. ( 25668110 )
2015
20
Kimura disease: A rare case of bilateral infra-auricular masses. ( 26831431 )
2015
21
Kimura disease associated with severe visual dysfunction due to remarkable periorbital involvement. ( 26031497 )
2015
22
Paradoxical brain embolism associated with Kimura disease mimics watershed infarction. ( 25447210 )
2015
23
Retrospective Multicentric Study of 25 Kimura Disease Patients: Emphasis on Therapeutics and Shared Features with Cutaneous IgG4-Related Disease. ( 26452023 )
2015
24
Kimura Disease Presenting As an Eyelid Mass in a Young Asian Male. ( 26080258 )
2015
25
Kimura disease accompanied with nephrotic syndrome in a 45-year-old male. ( 25928198 )
2015
26
Kimura Disease Mimicking an Aneurysm of the Radial Artery. ( 26362092 )
2015
27
Unusual Cause of Swelling in the Upper Limb: Kimura Disease. ( 26421119 )
2015
28
Kimura Disease Simulating Hodgkin's Lymphoma on (18)F FDG PET-CT: Report of a Case. ( 26396638 )
2014
29
Kimura disease complicated with bowel infarction and multiple arterial thromboses in the extremities. ( 24356478 )
2014
30
Kimura disease associated with IgA nephropathy. ( 24656163 )
2014
31
Preliminary study of diffusion-weighted imaging and magnetic resonance spectroscopy imaging in kimura disease. ( 25377973 )
2014
32
Kimura disease manifesting as synchronous bilateral parotid swelling in a young middle-eastern patient. ( 25544928 )
2014
33
Kimura Disease of the Epiglottis: A Case Report and Review of Literature. ( 23907346 )
2013
34
The false-positive finding of left pulmonary Kimura disease on 18F-FDG PET/CT. ( 23510880 )
2013
35
Intraparotid Kimura disease. ( 23021002 )
2013
36
Kimura Disease: rare cause of a slowly progressive orbital mass. ( 24119195 )
2013
37
Kimura disease involving a caruncle. ( 23543681 )
2013
38
Epitrochlear mass in a patient on maintenance hemodialysis--Kimura disease. ( 22280213 )
2012
39
Kimura disease: diagnostic challenges and clinical management. ( 21763034 )
2012
40
Kimura disease: CT and MR imaging findings. ( 22173767 )
2012
41
Elevated numbers of cells producing interleukin-5 and interleukin-10 in a boy with Kimura disease. ( 22627370 )
2012
42
Treatment of Kimura disease with photodynamic therapy: a case study. ( 22369733 )
2012
43
Kimura disease in the parotid gland. ( 21239930 )
2011
44
Treatment of Kimura disease with intravenous immunoglobulin. ( 22106083 )
2011
45
Kimura disease: a case report and review of the literature with a new management protocol. ( 21423602 )
2011
46
Microfilaria in lymph node mimicking Kimura disease. ( 23508372 )
2011
47
Head and neck MRI of Kimura disease. ( 21849365 )
2011
48
Kimura disease with necrosis of the limbs and mononeuritis multiplex. ( 21418278 )
2011
49
Juvenile temporal arteritis with perifollicular lymphoid proliferation resembling Kimura disease. Report of a case. ( 21182505 )
2011
50
Kimura disease in children: a case report and a summary of the literature in Chinese. ( 21436734 )
2011

Variations for Kimura Disease

Expression for Kimura Disease

Search GEO for disease gene expression data for Kimura Disease.

Pathways for Kimura Disease

Pathways related to Kimura Disease according to GeneCards Suite gene sharing:

(show all 21)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.29 CCL11 CCL5 CCR3 IL4 IL5 TSLP
2
Show member pathways
13.1 CCL11 CCL5 CCR3 IL4 IL5
3
Show member pathways
13.04 CCL11 CCL5 IL33 IL4 IL5
4
Show member pathways
12.96 CCL11 CCL5 CCR3 IL4 IL5
5
Show member pathways
12.55 CCL11 IL4 IL5 RNASE3
6
Show member pathways
12.09 CCL11 CCL5 CCR3
7
Show member pathways
12.08 CCL11 IL4 IL5
8
Show member pathways
11.94 IL4 IL5 TSLP
9
Show member pathways
11.7 CCL11 CCL5 CCR3
10 11.65 CCR3 IL4 IL5
11 11.46 IL33 IL4 IL5 TSLP
12 11.34 CCL11 IL4 IL5
13 11.29 CCL5 IL4
14 11.13 CCL11 IL33 IL4 IL5
15 11.11 IL4 IL5
16 11.06 IL4 IL5
17 10.96 IL4 IL5
18 10.85 CCL11 CCL5 IL4 IL5
19 10.82 CCL11 CCL5 CCR3 IL4 IL5
20 10.76 IL33 IL4 IL5 TSLP
21 10.63 IL4 IL5

GO Terms for Kimura Disease

Cellular components related to Kimura Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL11 CCL5 IL33 IL4 IL5 RNASE3
2 extracellular space GO:0005615 9.17 CCL11 CCL5 IL33 IL4 IL5 RNASE3

Biological processes related to Kimura Disease according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.73 CCL11 CCL5 IL4 IL5
2 inflammatory response GO:0006954 9.67 CCL11 CCL5 CCR3 IL5
3 positive regulation of T cell proliferation GO:0042102 9.56 CCL5 IL4
4 response to cytokine GO:0034097 9.55 CCL5 IL4
5 cellular response to interferon-gamma GO:0071346 9.54 CCL11 CCL5
6 cellular defense response GO:0006968 9.52 CCR3 IL4
7 monocyte chemotaxis GO:0002548 9.51 CCL11 CCL5
8 positive regulation of B cell proliferation GO:0030890 9.49 IL4 IL5
9 innate immune response in mucosa GO:0002227 9.48 IL4 RNASE3
10 positive regulation of JAK-STAT cascade GO:0046427 9.46 CCL5 IL5
11 positive regulation of immunoglobulin secretion GO:0051024 9.4 IL33 IL5
12 eosinophil chemotaxis GO:0048245 9.32 CCL11 CCL5
13 positive regulation of interleukin-13 production GO:0032736 9.26 IL33 IL4
14 type 2 immune response GO:0042092 9.16 IL33 IL4
15 chemokine-mediated signaling pathway GO:0070098 9.13 CCL11 CCL5 CCR3
16 chemotaxis GO:0006935 8.92 CCL11 CCL5 CCR3 IL4

Molecular functions related to Kimura Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CCL11 CCL5 IL33 IL4 IL5 TSLP
2 chemokine activity GO:0008009 8.96 CCL11 CCL5

Sources for Kimura Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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