MCID: LCT001
MIFTS: 52

Lactic Acidosis malady

Categories: Genetic diseases, Metabolic diseases, Rare diseases

Aliases & Classifications for Lactic Acidosis

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Aliases & Descriptions for Lactic Acidosis:

Name: Lactic Acidosis 11 26 13
Acidosis, Lactic 38 67
 
Acidosis Lactic 49

Classifications:



External Ids:

Disease Ontology11 DOID:3650
ICD1029 E87.2
SNOMED-CT61 91273001
MeSH38 D000140
NCIt44 C98969

Summaries for Lactic Acidosis

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Disease Ontology:11 An acquired metabolic disease that has material basis in low pH in body tissues and blood accompanied by the buildup of lactate especially D-lactate.

MalaCards based summary: Lactic Acidosis, also known as acidosis, lactic, is related to mitochondrial complex i deficiency and myoclonic epilepsy associated with ragged-red fibers, and has symptoms including symptomatic hyperlactatemia and acetonaemic vomiting. An important gene associated with Lactic Acidosis is YARS2 (Tyrosyl-TRNA Synthetase 2), and among its related pathways are Propanoate metabolism and Pyruvate metabolism. Affiliated tissues include kidney, liver and heart.

Wikipedia:70 Lactic acidosis is a medical condition characterized by the buildup of lactate (especially L-lactate) in... more...

Related Diseases for Lactic Acidosis

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Diseases in the Lactic Acidosis family:

Lactic Acidosis Congenital Infantile Fatal Infantile Lactic Acidosis

Diseases related to Lactic Acidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 238)
idRelated DiseaseScoreTop Affiliating Genes
1mitochondrial complex i deficiency31.5MT-ND1, MT-ND4, MT-ND5, MT-ND6
2myoclonic epilepsy associated with ragged-red fibers27.8LARS2, MT-ATP6, MT-CO3, MT-ND1, MT-ND4, MT-ND5
3mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes12.5
4mitochondrial myopathy with lactic acidosis12.4
5myopathy, lactic acidosis, and sideroblastic anemia 212.4
6myopathy with lactic acidosis, hereditary12.3
7hydrops, lactic acidosis, and sideroblastic anemia12.2
8myopathy, lactic acidosis, and sideroblastic anemia 312.2
9myopathy, lactic acidosis, and sideroblastic anemia12.1
10fatal infantile lactic acidosis12.1
11lactic acidosis congenital infantile12.0
12succinic acidemia lactic acidosis congenital11.9
13infantile myopathy and lactic acidosis11.9
14gracile syndrome11.8
15mitochondrial myopathy and sideroblastic anemia 111.8
16dihydrolipoamide dehydrogenase deficiency11.8
17pyruvate dehydrogenase e1-alpha deficiency11.8
18mitochondrial dna depletion syndrome 911.7
19pyruvate carboxylase deficiency11.7
20pyruvate dehydrogenase lipoic acid synthetase deficiency11.7
21combined oxidative phosphorylation deficiency 1011.6
22combined oxidative phosphorylation deficiency 1811.6
23combined oxidative phosphorylation deficiency 1911.5
24mitochondrial phosphate carrier deficiency11.5
25mitochondrial disorders11.2
26pyruvate dehydrogenase phosphatase deficiency11.2
27metabolic acidosis11.2
28combined oxidative phosphorylation deficiency 211.1
29combined oxidative phosphorylation deficiency 311.1
30multiple mitochondrial dysfunctions syndrome 111.0
31pyruvate dehydrogenase e1-beta deficiency11.0
32combined oxidative phosphorylation deficiency 1411.0
33mitochondrial dna depletion syndrome 1311.0
34combined oxidative phosphorylation deficiency 1111.0
35sengers syndrome11.0
36mitochondrial dna depletion syndrome 8a11.0
37mitochondrial complex iii deficiency, nuclear type 611.0
38combined oxidative phosphorylation deficiency 1711.0
39combined oxidative phosphorylation deficiency 2311.0
40barth syndrome11.0
41maple syrup urine disease, type ii10.9
42leigh syndrome, french-canadian type10.9
43myopathy with deficiency of iron-sulfur cluster assembly enzyme10.9
44multiple mitochondrial dysfunctions syndrome 310.8
45cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 410.8
46mitochondrial complex iv deficiency10.8
47multiple mitochondrial dysfunctions syndrome 210.8
48lipoyltransferase 1 deficiency10.8
49mitochondrial complex iii deficiency, nuclear type 110.8
50mitochondrial complex iii deficiency, nuclear type 710.8

Graphical network of the top 20 diseases related to Lactic Acidosis:



Diseases related to lactic acidosis

Symptoms for Lactic Acidosis

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UMLS symptoms related to Lactic Acidosis:


symptomatic hyperlactatemia, acetonaemic vomiting

Drugs & Therapeutics for Lactic Acidosis

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Drugs for Lactic Acidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 112)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1ParecoxibapprovedPhase 439198470-84-7
2
Epinephrineapproved, vet_approvedPhase 493351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
3
Celecoxibapproved, investigationalPhase 4435169590-42-52662
Synonyms:
169590-42-5
184007-95-2
1oq5
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
AC-4228
AC1L1E6K
AI-525
BIDD:GT0408
BRD-K02637541-001-02-4
BSPBio_003596
Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)
C07589
C105934
C17H14F3N3O2S
CCRIS 8679
CEL
CEP-33222
CHEBI:41423
CHEMBL118
CID2662
CPD000550473
Celebra
Celebrex
Celebrex (TN)
Celebrex, Celebra, Celecoxib
Celecox
Celecoxi
Celecoxib
Celecoxib (JAN/USAN/INN)
Celecoxib (SC-58635)
Celecoxib [Old RN]
Celecoxib [USAN]
Celecoxibum
Celocoxib
Célécoxib
D00567
DB00482
DivK1c_000893
Eurocox
FT-0080064
HMS1922G14
HMS2089L18
HMS2093I07
HMS502M15
HSDB 7038
I01-1033
IDI1_000893
KBio1_000893
KBio2_000912
 
KBio2_002351
KBio2_003480
KBio2_004919
KBio2_006048
KBio2_007487
KBio3_002830
KBio3_003037
KBioGR_000723
KBioGR_002351
KBioSS_000912
KBioSS_002354
LS-31667
MLS001165684
MLS001195656
MLS001304708
Medicoxib
MolPort-002-885-815
NCGC00091455-01
NCGC00091455-02
NCGC00091455-03
NCGC00091455-04
NCI60_041049
NINDS_000893
NSC719627
Onsenal
P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
Pfizer brand of celecoxib
S1261_Selleck
SAM002589995
SC 58635
SC-58553, SC-58635
SC-58635
SC58635
SMR000550473
SPBio_001512
SPECTRUM1503678
Solexa
Spectrum2_001576
Spectrum3_001996
Spectrum4_000182
Spectrum5_001324
Spectrum_000432
TL8001323
TPI-336
UNM-0000305813
Xilebao
YM 177
YM-177
YM177
ZINC02570895
cMAP_000027
celecoxib
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
4
Tramadolapproved, investigationalPhase 423227203-92-533741
Synonyms:
(+)-(R,R)-trans-Tramadol
(+)-Tramadol
(+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol
(+)-trans-Tramadol free ba
(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexan-1-ol
(1R,2R)-2-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexanol
(1R,2R)-2-[(dimethylamino)methyl]-1-[3-(methyloxy)phenyl]cyclohexanol
27203-92-5
AC1L1Q6E
AC1Q59O2
AKOS005066335
Amanda
Amanda (TN)
BIDD:GT0075
C07153
CHEMBL1066
CID33741
Crispin
D08623
DB00193
EINECS 248-319-6
HMS2090D10
Jsp005295
LS-57115
 
LS-57116
MLS000333190
MolPort-002-507-778
NCGC00159343-02
Ralivia ER
Ralivia Flashtab
Ralivia flashtab
SMR000436547
STOCK4S-19075
Tradonal odis
Tramadol
Tramadol (INN)
Tramadol HCl
Tramadol HCl BP/EP
Tramadol [INN:BAN]
Tramadol hydrochloride
Tramadolum
Tramadolum [INN-Latin]
Tramal
Tramodol Hcl
Tridural
UNII-39J1LGJ30J
Ultram
Ultram ER
Zydol
tramadol
5
Telbivudineapproved, investigationalPhase 4853424-98-4159269
Synonyms:
1-(2-Deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2-Deoxy-beta-L-erythropentafuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
1-(2-Deoxy-beta-L-ribofuranosyl)-5-methyluracil
1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
2'-Deoxy-L-thymidine
3424-98-4
AC-5632
AC1L4LJI
Beta-l-thymidine
CHEBI:17748
CHEMBL374731
CID159269
D06675
DB01265
Epavudine
I14-8810
L-DT
L-Deoxythymidine
L-Thymidine
L-dT
L-deoxythymidine
L-thymidine
 
LDT
LDT-600
LDT600
LLT
LS-186402
LS-187347
LdT
NB 02B
NV 02B
NV-02B
S1651_Selleck
Sebivo
Telbivudin
Telbivudine
Telbivudine (USAN/INN)
Telbivudine [USAN]
Tyzeka
Tyzeka (TN)
Tyzeka, Sebivo, Telbivudine
UNII-2OC4HKD3SF
ZINC00002159
beta-L-2'-Deoxythymidine
beta-L-Thymidine
6
Adefovir Dipivoxilapproved, investigationalPhase 4133142340-99-660871
Synonyms:
(((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate
((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid, diester with hydroxymethyl pivalate
142340-99-6
9-(2-((-Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine
9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine
AC-1693
AC1L1U36
ADEFOVIR DIPIVOXIL
ADV
AKOS005145737
Adefovir
Adefovir Pivoxil
Adefovir dipivoxil (USAN)
Adefovir pivoxil
Adefovir pivoxil (JAN)
Adefovirdipivoxl
Adefovirum
Adéfovir
Ambap142340-99-6
Bis(POM)-PMEA
Bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine
Bis(pom)PMEA
Bis-POM PMEA
Bis-POM PMEA, Adefovir Dipivoxil
Bis-POM PMEA, Preveon, Hepsera, Adefovir Dipivoxil
C20H32N5O8P
CHEMBL922
 
CID60871
D01655
DB00718
FT-0082875
GS 0840
GS 840
GS-0840
GS-840
Hepsera
Hepsera (TM)
Hepsera (TN)
I06-1150
I14-3234
LS-173141
MolPort-003-986-417
NCGC00164624-01
PMEA
Piv2PMEA
Preveon
Propanoic acid, 2,2-dimethyl-, (((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) ester
Propanoic acid,2,2-dimethyl-(((2-(6-amino-9H-purin-9-yl)ehtoxy)mehtyl)phosphinyldiene)bis(oxymehtylene)ester
S1718_Selleck
TL8000938
UNII-U6Q8Z01514
YouHeDing
ZINC03930376
[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
adefovir depivoxil
bis-POM PMEA
7
MetforminapprovedPhase 4, Phase 3, Phase 21746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
8
Stavudineapproved, investigationalPhase 4, Phase 2, Phase 31723056-17-518283
Synonyms:
1-(2,3-Dideoxy-beta-D-glycero-2-pentenofuranosyl)thymine
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
1-[5-(hydroxymethyl)-2,5-dihydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione & Colony-stimulating factor 2
132425-31-1
2',3' Didehydro 3' deoxythymidine
2',3'-Anhydrothymidine
2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE (DDI)
2',3'-Didehydro-2',3'-dideoxythmidine
2',3'-Didehydro-3'-deoxythimidine
2',3'-Didehydro-3'-deoxythymidine
3'- Azido-3'-deoxythymidine & Granulocyte-macrophage colony-stimulating factor
3'-Deoxy-2',3'-didehydrothymidine
3'-Deoxy-2'-thymidinene
3056-17-5
AC-5263
AC1L2BQ9
AC1Q6BSH
BB_NC-1008
BIDD:GT0082
BMY 27857
BMY-27857
BMY27857
BRN 0618327
Bristol-Myers Brand of Stavudine
Bristol-Myers Squibb Brand of Stavudine
C07312
CHEBI:207119
CHEMBL991
CID18283
CPD000058350
CPD000673569
D 1413
D 4T
D 4T (nucleoside)
D00445
D018119
D1413_SIGMA
D3580
D4T & GM-CSF
D4TMBY-27857-3
DB00649
Dideoxydidehydrothymidine
EU-0100336
Estavudina
Estavudina [INN-Spanish]
FT-0082665
 
HMS2051O20
HSDB 7338
LS-1160
Lopac0_000336
MLS000028546
MLS000759504
MLS001055348
MLS001077292
MolPort-002-507-283
NCGC00023212-03
NCGC00023212-04
NCGC00023212-05
NCGC00023212-07
NCGC00023212-08
NCGC00023212-09
NCGC00023212-10
NSC 163661
NSC163661
SAM001246729
SAM002589948
SMR000058350
SMR000673569
STK801888
STV
Sanilvudine
Sanilvudine (JAN)
Stavudin
Stavudine
Stavudine (USAN/INN)
Stavudine [USAN:BAN:INN]
Stavudine [USAN:INN:BAN]
Stavudine [Usan:Ban:Inn]
Stavudine, Monosodium Salt
Stavudinum
Stavudinum [INN-Latin]
Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)- (7CI,8CI)
UNII-BO9LE4QFZF
ZINC00137884
Zent
Zerit
Zerit (TN)
Zerit XR
Zerit Xr
Zerit(TM)
Zerut XR
d4T
ddeThd
ddeTyd
sanilvudine
stavudine
9
FenoldopamapprovedPhase 41367227-56-9, 67227-57-03341
Synonyms:
6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
67227-56-9
67227-57-0 (mesylate)
67287-54-1 (hydrobromide)
87900-90-1
9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
AC1L1FPQ
AC1Q3LHG
AR-1L4264
BPBio1_001265
BRD-A50684349-001-01-5
Biomol-NT_000042
C07693
CHEBI:5002
CHEMBL588
CID3341
Carlacor
Carlacor (TN)
D07946
DB00800
 
Fenodopam mesylate
Fenoldopam
Fenoldopam (INN)
Fenoldopam [INN:BAN]
Fenoldopamum
Fenoldopamum [Latin]
Fénoldopam
HMS2090G16
L000254
LS-27993
Lopac0_000556
NCGC00015444-05
NCGC00025246-02
NCGC00025246-03
PDSP1_001661
PDSP2_001645
SK&F-82526
SKF 82526
SKF 82526-J
SKF-82526J
UNII-INU8H2KAWG
fenoldopam
10
DopamineapprovedPhase 4375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
11
Entecavirapproved, investigationalPhase 4180142217-69-4153941
Synonyms:
142217-69-4
2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one--water (1/1)
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
209216-23-9
6-H-Purin-6-one-,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]
9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine monohydrate
AB1004838
AC-1593
AC1L4BEC
Anhydrous entecavir
BMS-200475
Baraclude
Baraclude (TN)
CHEBI:473990
CHEBI:59902
CHEMBL713
CID153941
 
D04008
D07896
DB00442
ETV
Entecavir
Entecavir (INN)
Entecavir (USAN)
Entecavir (anhydrous)
Entecavir anhydrous
Entecavir hydrate
Entecavir hydrate (JAN)
Entecavirum
FT-0083013
MolPort-005-942-963
S2128_Selleck
SBB066120
SQ-34676
TL8000933
ZINC03802690
entecavir monohydrate
12
Lamivudineapproved, investigationalPhase 4613134678-17-460825
Synonyms:
(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(+/-)-3TC
(+/-)-BCH-189
(+/-)-SddC
(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-2'-Deoxy-3'-thiacytidine
(-)-BCH 189
(-)-BCH-189
(-)-SddC
(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine
(-)NGPB-21
(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To
134678-17-4
2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)
3'-Thia-2',3'-dideoxycytidine
3TC
3TC & GNA
3TC & SST
3TC (AIDS INITIATIVE) (AIDS INITIATIVE)
3TC and NV-01
3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
480434-79-5
AC-1416
AC1L1TZZ
AC1Q6C34
BCH 189
BCH-189
BCH-790
BCH189
BIDD:GT0033
Bio-0652
C07065
C8H11N3O3S
CCRIS 9274
CHEBI:133986
CHEMBL141
CID60825
CPD000466319
D00353
D019259
 
DB00709
DRG-0126
DTHC
Epivir
Epivir (TN)
Epivir(TM)
Epivir-HBV
Epzicom
FT-0082667
GG-714
GR 109714X
GR-109714X
GR109714X
HHA & 3TC
HHA & Lamivudine
HMS2051D21
HSDB 7155
Hepitec
Heptivir
Heptodin
Heptovir
L0217
LMV
LS-2107
Lamivir
Lamivudin
Lamivudina
Lamivudine
Lamivudine & GNA
Lamivudine (JAN/USP/INN)
Lamivudine [USAN:BAN:INN]
Lamivudine [USAN:INN:BAN]
Lamivudine [Usan:Ban:Inn]
Lamivudine, (2S-cis)-Isomer
Lamivudinum
MLS000759424
MLS001424097
MolPort-002-507-347
NCGC00159341-03
NCGC00159341-04
NSC620753
S1706_Selleck
SAM001246582
SAM002589994
SMR000466319
STK801940
UNII-2T8Q726O95
ZINC00012346
Zeffix
Zefix
beta-L-2',3'-Dideoxy-3'-thiacytidine
beta-L-3'-Thia-2',3'-dideoxycytidine
lamivudine
13
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 2, Phase 3, Phase 1427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
14
Thiamineapproved, nutraceutical, vet_approvedPhase 4, Phase 2, Phase 3, Phase 19859-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
 
HSDB 220
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
15
Riboflavinapproved, nutraceutical, vet_approvedPhase 4, Phase 2, Phase 316583-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
16Antiviral AgentsPhase 4, Phase 2, Phase 39732
17Anti-Retroviral AgentsPhase 4, Phase 2, Phase 33232
18AdefovirPhase 4133
19Anti-Infective AgentsPhase 4, Phase 2, Phase 321402
20RacepinephrinePhase 4933
21Vasodilator AgentsPhase 43438
22Neurotransmitter AgentsPhase 417734
23Antihypertensive AgentsPhase 44095
24Peripheral Nervous System AgentsPhase 422776
25Epinephryl boratePhase 4933
26Nucleic Acid Synthesis InhibitorsPhase 4, Phase 2, Phase 34855
27Reverse Transcriptase InhibitorsPhase 4, Phase 2, Phase 31880
28Liver ExtractsPhase 43868
29insulinPhase 4, Phase 24524
30Central Nervous System DepressantsPhase 412806
31Hypoglycemic AgentsPhase 4, Phase 3, Phase 25733
32Psychotropic DrugsPhase 46279
33Tranquilizing AgentsPhase 44164
34Antipsychotic AgentsPhase 42359
35VitaminsPhase 4, Phase 2, Phase 3, Phase 15095
36MicronutrientsPhase 4, Phase 2, Phase 3, Phase 15802
37Trace ElementsPhase 4, Phase 2, Phase 3, Phase 15802
38Vitamin B ComplexPhase 4, Phase 2, Phase 3, Phase 14229
39NarcoticsPhase 43486
40AnalgesicsPhase 411287
41Cyclooxygenase 2 InhibitorsPhase 4616
42Cyclooxygenase InhibitorsPhase 42778
43Insulin, Globin ZincPhase 4, Phase 24523
44Antirheumatic AgentsPhase 410627
45Anti-Inflammatory Agents, Non-SteroidalPhase 44295
46Analgesics, Non-NarcoticPhase 46260
47Anti-Inflammatory AgentsPhase 410355
48Analgesics, OpioidPhase 43091
49Anti-HIV AgentsPhase 4, Phase 2, Phase 33100
50Dopamine agonistsPhase 4618

Interventional clinical trials:

(show top 50)    (show all 64)
idNameStatusNCT IDPhase
1Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart SurgeryUnknown statusNCT01524315Phase 4
2Metformin for Weight Control in Adolescents Taking Atypical AntipsychoticsUnknown statusNCT00845936Phase 4
3Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance After Gastrointestinal Laparoscopic SurgeryUnknown statusNCT01930318Phase 4
4Telbivudine Renoprotective Effect in Patients With the HBV-related Liver Cirrhosis: a Randomized Controlled TrialUnknown statusNCT01799486Phase 4
5Sodium Bicarbonate in Cardiopulmonary ResuscitationUnknown statusNCT01377337Phase 4
6Lactate Metabolism Study in HIV Infected PersonsCompletedNCT00202228Phase 4
7Fenoldopam and Splanchnic Perfusion During Cardiopulmonary BypassCompletedNCT00747331Phase 4
8Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)CompletedNCT01831934Phase 4
9The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) TrialCompletedNCT01438723Phase 4
10Body Weight Effects on Glucophage's Efficacy in Chinese Diagnosed T2DM PatientsCompletedNCT00778622Phase 4
11Lactic Acidosis During Entecavir(ETV)TreatmentTerminatedNCT01354652Phase 4
12Phase III Randomized Study of Sodium Dichloroacetate in Children With Congenital Lactic AcidosisCompletedNCT00004490Phase 3
13D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE)CompletedNCT00143702Phase 2, Phase 3
14RBC Transfusion in Severe Anemia With Lactic AcidosisCompletedNCT01586923Phase 3
15Dichloroacetate Treatment of Congenital Lactic Acidosis Phase B: Open LabelActive, not recruitingNCT01797276Phase 3
16Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial DiseaseEnrolling by invitationNCT02023866Phase 2, Phase 3
17Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:Not yet recruitingNCT02616484Phase 3
18Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot StudyTerminatedNCT00325910Phase 3
19Evaluating the Effectiveness of a Dichloroacetate in MELAS SyndromeUnknown statusNCT00068913Phase 2
20Phase IIb Study of MP4OX in Traumatic Hemorrhagic Shock PatientsCompletedNCT01262196Phase 2
21Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock PatientsCompletedNCT01004198Phase 2
22Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like EpisodesCompletedNCT00887562Phase 2
23Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic AcidemiaCompletedNCT00004493Phase 2
24SELESTIAL: Trial of Insulin to Control Blood Sugar After Acute Stroke Using Magnetic Resonance Imaging (MRI) End-PointsCompletedNCT00124826Phase 2
25Thiamine as a Metabolic Resuscitator in Septic ShockCompletedNCT01070810Phase 1, Phase 2
26The KHENERGY StudyRecruitingNCT02909400Phase 2
27A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial DiseaseEnrolling by invitationNCT02473445Phase 2
28Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac ArrestNot yet recruitingNCT02974257Phase 2
29The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal AdenocarcinomaNot yet recruitingNCT02978547Phase 2
30Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up StudyNot yet recruitingNCT02848508Phase 2
31Phase 2c Dose Comparison Study of MP4OX in TraumaWithdrawnNCT01973504Phase 2
32A Dose-escalating Clinical Trial With KH176CompletedNCT02544217Phase 1
33A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid TumoursCompletedNCT00566410Phase 1
34Anaplerotic Therapy in Propionic AcidemiaCompletedNCT00645879Phase 1
35Nitroglycerin Infusion During Cardiac SurgeryUnknown statusNCT01901419
36Lactic Acidosis During and After SeizuresUnknown statusNCT01833247
37Use of Phenoxybenzamine [PBZ] IV to Assist High Flow Low Pressure Perfusion [HFLPP] on Cardio-Pulmonary BypassUnknown statusNCT00620945
38Mitochondrial nt3243 A>G Mutation in TaiwanUnknown statusNCT02114554
39Psychophysical Aspects of Maximal Anaerobic PerformanceUnknown statusNCT01770288
40Effect of Blood Storage Age on the Resolution of Lactic Acidosis in Children With Severe Malarial Anemia at Mulago HospitalCompletedNCT01580111
41Safety of Continuing Metformin in Diabetic Patients With Normal Kidney Function Receiving Contrast MediaCompletedNCT01873859
42Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic AcidosisCompletedNCT00942123
43Metformin Treatment, Renal Function and Lactic AcidosisCompletedNCT01358994
44Prevention of Dichloroacetate ToxicityCompletedNCT00031161
45Dichloroacetate Kinetics, Metabolism and ToxicologyCompletedNCT00015015
46Pharmacotoxicology of Trichloroethylene MetabolitesCompletedNCT00874276
47Study of Blood Lactate Levels in Patients Treated With AntipsychoticsCompletedNCT01139463
48Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic AcidemiaCompletedNCT00004353
49Variation in Serum Levels of Metformin in Patients With Reduced Renal FunctionCompletedNCT00767351
50The Cytoadherence in Pediatric Malaria (CPM) StudyCompletedNCT00707200

Search NIH Clinical Center for Lactic Acidosis


Cochrane evidence based reviews: acidosis, lactic

Genetic Tests for Lactic Acidosis

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Genetic tests related to Lactic Acidosis:

id Genetic test Affiliating Genes
1 Lactic Acidosis26

Anatomical Context for Lactic Acidosis

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MalaCards organs/tissues related to Lactic Acidosis:

35
Kidney, Liver, Heart, Brain, B cells, Testes, Lung

Animal Models for Lactic Acidosis or affiliated genes

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Publications for Lactic Acidosis

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Articles related to Lactic Acidosis:

(show top 50)    (show all 759)
idTitleAuthorsYear
1
Recommendations for the Management of Strokelike Episodes in Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Strokelike Episodes. (26954033)
2016
2
Venlafaxine intoxication in an adolescent presenting with severe lactic acidosis. (27976562)
2016
3
Recoverable, Record-High Lactic Acidosis in a Patient with Glycogen Storage Disease Type 1: A Mixed Type A and Type B Lactate Disorder. (27974893)
2016
4
Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation. (27259254)
2016
5
Ombitasvir-Paritaprevir-Ritonavir-Dasabuvir (Viekira Pak)-Induced Lactic Acidosis. (27661862)
2016
6
I^ Agonist-induced lactic acidosis, an evidence-based approach to a critical question. (26830219)
2016
7
Metformin use and risk of lactic acidosis in people with diabetes with and without renal impairment: a cohort study in Denmark and the UK. (27504911)
2016
8
Lactic Acidosis in a Patient with Type 2 Diabetes Mellitus. (25762524)
2015
9
Metformin-Associated Lactic Acidosis in a Patient With Normal Renal Function. (26487794)
2015
10
EBV-driven HIV-associated diffuse large B-cell lymphoma causing profound lactic acidosis. (25247213)
2014
11
Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review. (23436666)
2013
12
Reversible lactic acidosis in a newborn with thiamine transporter-2 deficiency. (23589815)
2013
13
Type B lactic acidosis associated with multiple myeloma. (23759296)
2013
14
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome mimicking herpes simplex encephalitis on imaging studies. (23493219)
2013
15
A case of type B lactic acidosis in multiple myeloma. (23009980)
2013
16
Teaching NeuroImages: mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes. (23033508)
2012
17
Lactic acidosis after resuscitation with sodium acetate. (21227457)
2012
18
Metformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs. (22568883)
2012
19
Risk factors for symptomatic hyperlactatemia and lactic acidosis among combination antiretroviral therapy-treated adults in Botswana: results from a clinical trial. (22540188)
2012
20
Type 2 diabetes, metformin and lactic acidosis-defining the risk and promoting safe practice. (21978280)
2012
21
Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases. (21441284)
2011
22
Carotid dissection in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes. (21076841)
2011
23
A8344G mutation of the mitochondrial DNA with typical mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome. (22611618)
2011
24
Sodium bicarbonate use in the treatment of acute neonatal lactic acidosis: benefit or harm? (21576057)
2011
25
Severe lactic acidosis after an iatrogenic propylene glycol overdose. (20099997)
2010
26
Does metformin increase the risk of fatal or nonfatal lactic acidosis? (21121550)
2010
27
Lactic acidosis: recognition, kinetics, and associated prognosis. (20381719)
2010
28
Fatal lactic acidosis after prolonged linezolid exposure for treatment of multidrug-resistant tuberculosis. (19782904)
2009
29
Erlotinib-induced hepatitis complicated by fatal lactic acidosis in an elderly man with lung cancer. (19261961)
2009
30
Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis. (18782901)
2008
31
Is there a role for sodium bicarbonate in treating lactic acidosis from shock? (18614899)
2008
32
The genomic analysis of lactic acidosis and acidosis response in human cancers. (19057672)
2008
33
Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment. (18490795)
2008
34
Nonsense mutation in pseudouridylate synthase 1 (PUS1) in two brothers affected by myopathy, lactic acidosis and sideroblastic anaemia (MLASA). (17056637)
2007
35
Evolution of brain imaging abnormalities in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes. (17204916)
2006
36
Recurrent D-lactic acidosis in a child with short bowel syndrome. (15927940)
2005
37
Fatal lactic acidosis due to leukemic transformation in a patient with non-Hodgkin's lymphoma: case report. (16418152)
2005
38
Lactic acidosis following short-term propofol infusion may be an early warning of propofol infusion syndrome. (15841003)
2005
39
D(-)-lactic acid-producing probiotics, D(-)-lactic acidosis and infants. (15565207)
2004
40
Treatment of HAART-induced lactic acidosis with B vitamin supplements. (16215128)
2004
41
Comparison of conventional and diffusion-weighted MRI and proton MR spectroscopy in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like events. (14673554)
2004
42
Lactic acidosis after cardiac surgery is associated with adverse outcome. (15138095)
2004
43
Anaesthesia for an adolescent with mitochondrial encephalomyopathy-lactic acidosis-stroke-like episodes syndrome. (12791122)
2003
44
Fatal lactic acidosis and mimicking Guillain-BarrAc syndrome in an adolescent with human immunodeficiency virus infection. (12886900)
2003
45
Simvastatin-induced lactic acidosis: a rare adverse reaction? (12386648)
2002
46
Familial occurrence of intestinal obstruction in children with the syndrome of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). (9869067)
1998
47
Diagnosis of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes in a Chinese family by PCR/restriction enzyme analysis. (16696023)
1995
48
Pancreatic beta-cell secretory defect associated with mitochondrial point mutation of the tRNA(LEU(UUR)) gene: a study in seven families with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). (7988784)
1994
49
Proton magnetic resonance spectroscopy studies in lactic acidosis and mitochondrial disorders. (8412023)
1993
50
Lactic acidosis in biotin-responsive multiple carboxylase deficiency caused by holocarboxylase synthetase deficiency of early and late onset. (6811711)
1982

Variations for Lactic Acidosis

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Expression for genes affiliated with Lactic Acidosis

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Search GEO for disease gene expression data for Lactic Acidosis.

Pathways for genes affiliated with Lactic Acidosis

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Pathways related to Lactic Acidosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.0DLD, SUCLG1
2
Show member pathways
9.8DLD, PC, PDHA1
3
Show member pathways
9.7DLD, PDHA1, PDHX
4
Show member pathways
9.7DLD, PDHA1, PDHX
5
Show member pathways
9.5DLD, PC, PDHA1, SUCLG1
6
Show member pathways
9.5DLD, PC, PDHA1, SUCLG1
7
Show member pathways
9.5DLD, PC, PDHA1, PDHX
8
Show member pathways
9.2DLD, PDHA1, PDHX, PDP1, SUCLG1
9
Show member pathways
7.4COX14, DLD, MT-ATP6, MT-CO3, MT-ND1, MT-ND4
10
Show member pathways
6.6COX14, DLD, ISCU, MT-ATP6, MT-CO3, MT-ND1

GO Terms for genes affiliated with Lactic Acidosis

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Cellular components related to Lactic Acidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial respiratory chain complex IGO:000574710.5MT-ND1, MT-ND4, MT-ND5
2pyruvate dehydrogenase complexGO:004525410.1DLD, PDHA1, PDHX
3mitochondrial inner membraneGO:00057438.7MT-ATP6, MT-CO3, MT-ND1, MT-ND4, MT-ND5, MT-ND6
4mitochondrial matrixGO:00057598.1DLD, ISCU, LARS2, PC, PDHA1, PDHX
5mitochondrionGO:00057396.2COX14, DLD, ISCU, LARS2, MT-CO3, MT-ND1

Biological processes related to Lactic Acidosis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1response to hyperoxiaGO:005509310.2MT-ATP6, POLG
2acetyl-CoA biosynthetic process from pyruvateGO:000608610.1DLD, PDHA1
3mitochondrial acetyl-CoA biosynthetic process from pyruvateGO:00617329.9DLD, PDHA1, PDHX
4mitochondrial respiratory chain complex I assemblyGO:00329819.8MT-ND1, MT-ND4, MT-ND5, MT-ND6
5glyoxylate metabolic processGO:00464879.7DLD, PDHA1, PDHX
6regulation of acetyl-CoA biosynthetic process from pyruvateGO:00105109.7DLD, PDHA1, PDHX, PDP1
7tricarboxylic acid cycleGO:00060999.7DLD, PDHA1, SUCLG1
8pyruvate metabolic processGO:00060909.6DLD, PC, PDHA1, PDHX
9agingGO:00075689.4DLD, MT-ATP6, MT-ND4, POLG
10mitochondrial electron transport, NADH to ubiquinoneGO:00061209.3DLD, MT-ND1, MT-ND4, MT-ND5, MT-ND6

Molecular functions related to Lactic Acidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1pyruvate dehydrogenase (NAD+) activityGO:00346049.7DLD, PDHA1, PDHX
2NADH dehydrogenase (ubiquinone) activityGO:00081379.3MT-ND1, MT-ND4, MT-ND5, MT-ND6

Sources for Lactic Acidosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet