MDCIA
MCID: LM2001
MIFTS: 18

Lama2-Related Muscular Dystrophy (MDCIA) malady

Categories: Genetic diseases, Muscle diseases, Rare diseases, Neuronal diseases, Cardiovascular diseases

Aliases & Classifications for Lama2-Related Muscular Dystrophy

Aliases & Descriptions for Lama2-Related Muscular Dystrophy:

Name: Lama2-Related Muscular Dystrophy 23 24 25
Mdc1a 23 24 25
Laminin Alpha 2-Deficient Congenital Muscular Dystrophy 23 24
Merosin-Deficient Congenital Muscular Dystrophy Type 1a 23 24
Early-Onset Laminin Alpha 2 Deficiency 23 24
Late-Onset Laminin Alpha 2 Deficiency 23 24
Muscular Dystrophy Congenital, Merosin Negative 69
Laminin Alpha-2 Deficient Muscular Dystrophy 25
Muscular Dystrophy Due to Lama2 Deficiency 25
Merosin-Deficient Muscular Dystrophy 25
Laminin Alpha 2 Deficiency 25
Laminin, Alpha-2 13
Lama2 Md 25
Mdc 1a 24
Mdc Ia 24
Mdcia 24

Classifications:



Summaries for Lama2-Related Muscular Dystrophy

Genetics Home Reference : 25 LAMA2-related muscular dystrophy is a disorder that causes weakness and wasting (atrophy) of muscles used for movement (skeletal muscles). This condition generally appears in one of two ways: as a severe, early-onset type or a milder, late-onset form.

MalaCards based summary : Lama2-Related Muscular Dystrophy, also known as mdc1a, is related to muscular dystrophy, congenital merosin-deficient and congenital muscular dystrophy type 1a. An important gene associated with Lama2-Related Muscular Dystrophy is LAMA2 (Laminin Subunit Alpha 2). Affiliated tissues include skeletal muscle.

GeneReviews: NBK97333

Related Diseases for Lama2-Related Muscular Dystrophy

Diseases in the Muscular Dystrophy family:

Muscular Dystrophy, Congenital Muscular Dystrophy, Congenital, 1b
Congenital Muscular Dystrophy Due to Lmna Mutation Lama2-Related Muscular Dystrophy
Congenital Muscular Dystrophy Due to Dystroglycanopathy Congenital Muscular Dystrophy Type 1a
Progressive Muscular Dystrophy

Diseases related to Lama2-Related Muscular Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 muscular dystrophy, congenital merosin-deficient 11.4
2 congenital muscular dystrophy type 1a 11.1
3 muscular dystrophy 10.3
4 myopathy 10.1
5 collagen vi-related myopathy 10.1

Graphical network of the top 20 diseases related to Lama2-Related Muscular Dystrophy:



Diseases related to Lama2-Related Muscular Dystrophy

Symptoms & Phenotypes for Lama2-Related Muscular Dystrophy

Drugs & Therapeutics for Lama2-Related Muscular Dystrophy

Interventional clinical trials:


id Name Status NCT ID Phase
1 LAMA2-related Muscular Dystrophy Brain Study Withdrawn NCT01952028

Search NIH Clinical Center for Lama2-Related Muscular Dystrophy

Genetic Tests for Lama2-Related Muscular Dystrophy

Genetic tests related to Lama2-Related Muscular Dystrophy:

id Genetic test Affiliating Genes
1 Lama2-Related Muscular Dystrophy 24 LAMA2

Anatomical Context for Lama2-Related Muscular Dystrophy

MalaCards organs/tissues related to Lama2-Related Muscular Dystrophy:

39
Skeletal Muscle

Publications for Lama2-Related Muscular Dystrophy

Articles related to Lama2-Related Muscular Dystrophy:

id Title Authors Year
1
IGF-1/GH axis enhances losartan treatment in Lama2-related muscular dystrophy. ( 27798092 )
2016
2
Upper extremity outcome measures for collagen VI-related myopathy and LAMA2-related muscular dystrophy. ( 28087121 )
2016
3
Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy. ( 26304763 )
2015
4
Results of a two-year pilot study of clinical outcome measures in collagen VI-related myopathy and LAMA2-related muscular dystrophy. ( 25307854 )
2014
5
LAMA2-Related Muscular Dystrophy ( 22675738 )
1993

Variations for Lama2-Related Muscular Dystrophy

Expression for Lama2-Related Muscular Dystrophy

Search GEO for disease gene expression data for Lama2-Related Muscular Dystrophy.

Pathways for Lama2-Related Muscular Dystrophy

GO Terms for Lama2-Related Muscular Dystrophy

Sources for Lama2-Related Muscular Dystrophy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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