Lama2-Related Muscular Dystrophy disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Aliases & Classifications for Lama2-Related Muscular Dystrophy

Sources:
¹²diseasecard, ²³GeneReviews, ²⁴GeneTests, ²⁵Genetics Home Reference, ⁶⁸UMLS
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Aliases & Descriptions for Lama2-Related Muscular Dystrophy:

Name: Lama2-Related Muscular Dystrophy ²³ ²⁴ ²⁵

Mdc1a ²³ ²⁴ ²⁵

Laminin Alpha 2-Deficient Congenital Muscular Dystrophy ²³ ²⁴

Merosin-Deficient Congenital Muscular Dystrophy Type 1a ²³ ²⁴

Early-Onset Laminin Alpha 2 Deficiency ²³ ²⁴

Late-Onset Laminin Alpha 2 Deficiency ²³ ²⁴

Muscular Dystrophy Congenital, Merosin Negative ⁶⁸

Laminin Alpha-2 Deficient Muscular Dystrophy ²⁵

Muscular Dystrophy Due to Lama2 Deficiency ²⁵

Merosin-Deficient Muscular Dystrophy ²⁵

Laminin Alpha 2 Deficiency ²⁵

Laminin, Alpha-2 ¹²

Lama2 Md ²⁵

Mdc 1a ²⁴

Mdc Ia ²⁴

Mdcia ²⁴

Classifications:

MalaCards categories:
Global: Genetic diseases, Rare diseases
Anatomical: Muscle diseases, Neuronal diseases, Cardiovascular diseases

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Summaries for Lama2-Related Muscular Dystrophy

Sources:
²³GeneReviews, ²⁵Genetics Home Reference, ³⁶MalaCards
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Genetics Home Reference:²⁵ LAMA2-related muscular dystrophy is a disorder that causes weakness and wasting (atrophy) of muscles used for movement (skeletal muscles). This condition generally appears in one of two ways: as a severe, early-onset type or a milder, late-onset form.

MalaCards based summary: Lama2-Related Muscular Dystrophy, also known as mdc1a, is related to muscular dystrophy, congenital merosin-deficient and congenital muscular dystrophy type 1a. An important gene associated with Lama2-Related Muscular Dystrophy is LAMA2 (Laminin Subunit Alpha 2). Affiliated tissues include skeletal muscle.

GeneReviews for NBK97333

Related Diseases for Lama2-Related Muscular Dystrophy

Sources:
²⁰GeneAnalytics, ²¹GeneCards
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Diseases in the Muscular Dystrophy family:

Muscular Dystrophy, Congenital	Muscular Dystrophy, Congenital, 1b
Congenital Muscular Dystrophy Due to Lmna Mutation	lama2-related muscular dystrophy
Congenital Muscular Dystrophy Due to Dystroglycanopathy	Congenital Muscular Dystrophy Type 1a
Progressive Muscular Dystrophy

Diseases related to Lama2-Related Muscular Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

id	Related Disease	Score
1	muscular dystrophy, congenital merosin-deficient	11.4
2	congenital muscular dystrophy type 1a	11.1
3	muscular dystrophy	10.3
4	myopathy	10.1
5	collagen vi-related myopathy	10.1

Graphical network of diseases related to Lama2-Related Muscular Dystrophy:

Symptoms & Phenotypes for Lama2-Related Muscular Dystrophy

Drugs & Therapeutics for Lama2-Related Muscular Dystrophy

Sources:
⁴ClinicalTrials
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Interventional clinical trials:

id	Name	Status	NCT ID	Phase
1	LAMA2-related Muscular Dystrophy Brain Study	Withdrawn	NCT01952028

Search NIH Clinical Center for Lama2-Related Muscular Dystrophy

Genetic Tests for Lama2-Related Muscular Dystrophy

Sources:
²⁴GeneTests
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Genetic tests related to Lama2-Related Muscular Dystrophy:

id	Genetic test	Affiliating Genes
1	Lama2-Related Muscular Dystrophy²⁴	LAMA2

Anatomical Context for Lama2-Related Muscular Dystrophy

Sources:
³⁶MalaCards
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MalaCards organs/tissues related to Lama2-Related Muscular Dystrophy:

³⁶

Skeletal muscle

Publications for Lama2-Related Muscular Dystrophy

Sources:
⁵⁷PubMed
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Articles related to Lama2-Related Muscular Dystrophy:

id	Title	Authors	Year
1	IGF-1/GH axis enhances losartan treatment in Lama2-related muscular dystrophy. (27798092)	Accorsi A.... Girgenrath M.	2016
2	Upper extremity outcome measures for collagen VI-related myopathy and LAMA2-related muscular dystrophy. (28087121)	Bendixen R.M.... Meilleur K.G.	2016
3	Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy. (26304763)	Ding J.... Xiong H.	2015
4	Results of a two-year pilot study of clinical outcome measures in collagen VI-related myopathy and LAMA2-related muscular dystrophy. (25307854)	Meilleur K.G.... BAPnnemann C.G.	2014
5	LAMA2-Related Muscular Dystrophy (22675738)	Pagon R.A.... Stephens K.	1993