MCID: LM2001
MIFTS: 17

Lama2-Related Muscular Dystrophy malady

Categories: Genetic diseases, Muscle diseases, Rare diseases, Neuronal diseases

Aliases & Classifications for Lama2-Related Muscular Dystrophy

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Aliases & Descriptions for Lama2-Related Muscular Dystrophy:

Name: Lama2-Related Muscular Dystrophy 22 23 24
Mdc1a 22 23 24 48
Laminin Alpha 2-Deficient Congenital Muscular Dystrophy 22 23
Merosin-Deficient Congenital Muscular Dystrophy Type 1a 22 23
Early-Onset Laminin Alpha 2 Deficiency 22 23
Late-Onset Laminin Alpha 2 Deficiency 22 23
Muscular Dystrophy Congenital, Merosin Negative 66
Laminin Alpha-2 Deficient Muscular Dystrophy 24
 
Muscular Dystrophy Due to Lama2 Deficiency 24
Merosin-Deficient Muscular Dystrophy 24
Laminin Alpha 2 Deficiency 24
Laminin, Alpha-2 12
Lama2 Md 24
Mdc 1a 23
Mdc Ia 23
Mdcia 23

Classifications:



Summaries for Lama2-Related Muscular Dystrophy

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Genetics Home Reference:24 LAMA2-related muscular dystrophy is a disorder that causes weakness and wasting (atrophy) of muscles used for movement (skeletal muscles). This condition generally appears in one of two ways: as a severe, early-onset type or a milder, late-onset form.

MalaCards based summary: Lama2-Related Muscular Dystrophy, also known as mdc1a, is related to muscular dystrophy, congenital merosin-deficient and congenital muscular dystrophy type 1a. An important gene associated with Lama2-Related Muscular Dystrophy is LAMA2 (Laminin Subunit Alpha 2). Affiliated tissues include skeletal muscle and brain.

GeneReviews summary for NBK97333

Related Diseases for Lama2-Related Muscular Dystrophy

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Diseases in the Muscular Dystrophy family:

Muscular Dystrophy, Congenital Muscular Dystrophy, Congenital, 1b
lama2-related muscular dystrophy Congenital Muscular Dystrophy Type 1a
Progressive Muscular Dystrophy

Diseases related to Lama2-Related Muscular Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1muscular dystrophy, congenital merosin-deficient11.4
2congenital muscular dystrophy type 1a11.2
3muscular dystrophy10.3
4myopathy10.1
5collagen vi-related myopathy10.1

Graphical network of diseases related to Lama2-Related Muscular Dystrophy:



Diseases related to lama2-related muscular dystrophy

Symptoms for Lama2-Related Muscular Dystrophy

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Drugs & Therapeutics for Lama2-Related Muscular Dystrophy

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Congenital Muscle Disease Study of Patient and Family Reported Medical InformationRecruitingNCT01403402
2LAMA2-related Muscular Dystrophy Brain StudyWithdrawnNCT01952028

Search NIH Clinical Center for Lama2-Related Muscular Dystrophy

Genetic Tests for Lama2-Related Muscular Dystrophy

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Genetic tests related to Lama2-Related Muscular Dystrophy:

id Genetic test Affiliating Genes
1 Lama2-Related Muscular Dystrophy23 LAMA2

Anatomical Context for Lama2-Related Muscular Dystrophy

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MalaCards organs/tissues related to Lama2-Related Muscular Dystrophy:

34
Skeletal muscle, Brain

Animal Models for Lama2-Related Muscular Dystrophy or affiliated genes

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Publications for Lama2-Related Muscular Dystrophy

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Articles related to Lama2-Related Muscular Dystrophy:

idTitleAuthorsYear
1
Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy. (26304763)
2015
2
Results of a two-year pilot study of clinical outcome measures in collagen VI-related myopathy and LAMA2-related muscular dystrophy. (25307854)
2014
3
LAMA2-Related Muscular Dystrophy (22675738)
1993

Variations for Lama2-Related Muscular Dystrophy

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Expression for genes affiliated with Lama2-Related Muscular Dystrophy

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Search GEO for disease gene expression data for Lama2-Related Muscular Dystrophy.

Pathways for genes affiliated with Lama2-Related Muscular Dystrophy

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GO Terms for genes affiliated with Lama2-Related Muscular Dystrophy

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Sources for Lama2-Related Muscular Dystrophy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet