MCID: LM2001
MIFTS: 19

Lama2-Related Muscular Dystrophy malady

Categories: Genetic diseases, Muscle diseases, Rare diseases, Neuronal diseases, Cardiovascular diseases

Aliases & Classifications for Lama2-Related Muscular Dystrophy

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Aliases & Descriptions for Lama2-Related Muscular Dystrophy:

Name: Lama2-Related Muscular Dystrophy 23 24 25
Mdc1a 23 24 25 49
Laminin Alpha 2-Deficient Congenital Muscular Dystrophy 23 24
Merosin-Deficient Congenital Muscular Dystrophy Type 1a 23 24
Early-Onset Laminin Alpha 2 Deficiency 23 24
Late-Onset Laminin Alpha 2 Deficiency 23 24
Muscular Dystrophy Congenital, Merosin Negative 67
Laminin Alpha-2 Deficient Muscular Dystrophy 25
 
Muscular Dystrophy Due to Lama2 Deficiency 25
Merosin-Deficient Muscular Dystrophy 25
Laminin Alpha 2 Deficiency 25
Laminin, Alpha-2 12
Lama2 Md 25
Mdc 1a 24
Mdc Ia 24
Mdcia 24

Classifications:



Summaries for Lama2-Related Muscular Dystrophy

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Genetics Home Reference:25 LAMA2-related muscular dystrophy is a disorder that causes weakness and wasting (atrophy) of muscles used for movement (skeletal muscles). This condition generally appears in one of two ways: as a severe, early-onset type or a milder, late-onset form.

MalaCards based summary: Lama2-Related Muscular Dystrophy, also known as mdc1a, is related to congenital muscular dystrophy type 1a and muscular dystrophy, congenital merosin-deficient. An important gene associated with Lama2-Related Muscular Dystrophy is LAMA2 (Laminin Subunit Alpha 2). Affiliated tissues include skeletal muscle and brain.

GeneReviews for NBK97333

Related Diseases for Lama2-Related Muscular Dystrophy

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Graphical network of diseases related to Lama2-Related Muscular Dystrophy:



Diseases related to lama2-related muscular dystrophy

Symptoms for Lama2-Related Muscular Dystrophy

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Drugs & Therapeutics for Lama2-Related Muscular Dystrophy

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Congenital Muscle Disease Study of Patient and Family Reported Medical InformationRecruitingNCT01403402
2LAMA2-related Muscular Dystrophy Brain StudyWithdrawnNCT01952028

Search NIH Clinical Center for Lama2-Related Muscular Dystrophy

Genetic Tests for Lama2-Related Muscular Dystrophy

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Genetic tests related to Lama2-Related Muscular Dystrophy:

id Genetic test Affiliating Genes
1 Lama2-Related Muscular Dystrophy24 LAMA2

Anatomical Context for Lama2-Related Muscular Dystrophy

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MalaCards organs/tissues related to Lama2-Related Muscular Dystrophy:

35
Skeletal muscle, Brain

Animal Models for Lama2-Related Muscular Dystrophy or affiliated genes

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Publications for Lama2-Related Muscular Dystrophy

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Articles related to Lama2-Related Muscular Dystrophy:

idTitleAuthorsYear
1
Upper extremity outcome measures for collagen VI-related myopathy and LAMA2-related muscular dystrophy. (28087121)
2016
2
IGF-1/GH axis enhances losartan treatment in Lama2-related muscular dystrophy. (27798092)
2016
3
Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy. (26304763)
2015
4
Results of a two-year pilot study of clinical outcome measures in collagen VI-related myopathy and LAMA2-related muscular dystrophy. (25307854)
2014
5
LAMA2-Related Muscular Dystrophy (22675738)
1993

Variations for Lama2-Related Muscular Dystrophy

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Expression for genes affiliated with Lama2-Related Muscular Dystrophy

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Search GEO for disease gene expression data for Lama2-Related Muscular Dystrophy.

Pathways for genes affiliated with Lama2-Related Muscular Dystrophy

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GO Terms for genes affiliated with Lama2-Related Muscular Dystrophy

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Sources for Lama2-Related Muscular Dystrophy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet