MCID: LNG004
MIFTS: 29

Langerhans Cell Sarcoma malady

Rare diseases, Blood diseases, Cancer diseases categories

Summaries for Langerhans Cell Sarcoma

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Disease Ontology:10 A histiocytic and dendritic cell cancer that derives from the lymph nodes, derives from the skin, derives from the liver, derives from the spleen and derives from bones.

MalaCards based summary: Langerhans Cell Sarcoma, also known as malignant langerhans cell sarcoma, is related to sarcoma and langerhans-cell histiocytosis. An important gene associated with Langerhans Cell Sarcoma is CD207 (CD207 molecule, langerin). The compound lipid have been mentioned in the context of this disorder. Affiliated tissues include bone, spleen and lung.

Wikipedia:65 Langerhans cell sarcoma is a form of malignant histiocytosis. It should not be confused with Langerhans... more...

Aliases & Classifications for Langerhans Cell Sarcoma

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Sources:
10Disease Ontology, 43NIH Rare Diseases, 12DISEASES, 49Orphanet, 62UMLS, 35MeSH, 57SNOMED-CT, 40NCIt, 36MESH via Orphanet, 28ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Langerhans Cell Sarcoma, Aliases & Descriptions:

Name: Langerhans Cell Sarcoma 10 43 12 49 62
 
Malignant Langerhans Cell Sarcoma 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

49
langerhans cell sarcoma:
Age of onset: All ages


External Ids:

Disease Ontology10 DOID:7146
MeSH35 D054752
NCIt40 C6921
Orphanet49 86897
SNOMED-CT57 128814006
MESH via Orphanet36 D054752
ICD10 via Orphanet28 C96.4
UMLS via Orphanet63 C1260327

Related Diseases for Langerhans Cell Sarcoma

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Diseases related to Langerhans Cell Sarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1sarcoma31.4S100B, CD1A, CD207
2langerhans-cell histiocytosis30.2CD1A, CD207
3histiocytosis30.2S100B, CD207, CD1A
4leukemia10.4
5cervicitis10.3
6wilms tumor10.2
7peritonitis10.2
8dendritic cell tumor10.2
9melanoma10.0S100B, CD1A
10ipex syndrome10.0S100B, CD207

Graphical network of diseases related to Langerhans Cell Sarcoma:



Diseases related to langerhans cell sarcoma

Symptoms for Langerhans Cell Sarcoma

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Drugs & Therapeutics for Langerhans Cell Sarcoma

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Drug clinical trials:

Search ClinicalTrials for Langerhans Cell Sarcoma

Search NIH Clinical Center for Langerhans Cell Sarcoma

Genetic Tests for Langerhans Cell Sarcoma

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Anatomical Context for Langerhans Cell Sarcoma

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MalaCards organs/tissues related to Langerhans Cell Sarcoma:

33
Bone, Spleen, Lung, Lymph node, Skin

Animal Models for Langerhans Cell Sarcoma or affiliated genes

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Publications for Langerhans Cell Sarcoma

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Articles related to Langerhans Cell Sarcoma:

(show all 39)
idTitleAuthorsYear
1
Diagnostic Value of Wilms Tumor 1 and CD44 in Langerhans Cell Sarcoma: Case Series of 4 Patients. (25837753)
2015
2
Langerhans cell sarcoma: A systematic review. (25805533)
2015
3
High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. (24834110)
2014
4
Clinical experience of bendamustine for adult Langerhans cell sarcoma. (24881923)
2014
5
Rare case of Langerhans cell sarcoma with cutaneous manifestation arising on the inguinal region. (25387842)
2014
6
Langerhans cell sarcoma: case report and review of world literature. (24942035)
2014
7
A case of an adult Langerhans cell sarcoma. (25312302)
2014
8
Cutaneous Langerhans cell sarcoma relapsing systemically: Complete remission with the EPIG regimen. (25186787)
2014
9
Langerhans cell sarcoma: a case report. (23590692)
2013
10
Expression and anatomical distribution of TIM-containing molecules in Langerhans cell sarcoma. (23264111)
2013
11
Langerhans cell sarcoma: a case report and review of the literature. (23557341)
2013
12
Langerhans cell sarcoma in two young children: imaging findings on initial presentation and recurrence. (23690723)
2013
13
Langerhans cell sarcoma of the nasopharynx: a rare case. (24215052)
2013
14
Paraneoplastic disseminated lentigines heralding aggressive Langerhans cell sarcoma. (22992981)
2013
15
Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature. (23051626)
2013
16
Unusual cutaneous Langerhans cell sarcoma without extracutaneous involvement. (23388086)
2013
17
Langerhans Cell Sarcoma Arising from Chronic Lymphocytic Lymphoma/Small Lymphocytic Leukemia: Lineage Analysis and BRAF V600E Mutation Study. (23923114)
2013
18
Langerhans Cell Sarcoma in a Chronic Myelogenous Leukemia Patient Undergoing Imatinib Mesylate Therapy: A Case Study and Review of the Literature. (24008437)
2013
19
Langerhans cell sarcoma in the cervical lymph node: a case report and literature review. (23207655)
2013
20
Langerhans cell sarcoma in a patient with hairy cell leukemia: common clonal origin indicated by identical immunoglobulin gene rearrangements. (22616604)
2012
21
Multifocal Langerhans cell sarcoma involving epidermis: a case report and review. (22889043)
2012
22
The characteristic expression of B7-associated proteins in Langerhans cell sarcoma. (22305414)
2012
23
The characteristics of FDG PET/CT imaging in pulmonary Langerhans cell sarcoma. (22475903)
2012
24
Langerhans cell sarcoma with an aberrant cytoplasmic CD3 expression. (23006414)
2012
25
Langerhans cell sarcoma of the cervical lymph node: a case report and literature review. (20554413)
2010
26
Langerhans cell sarcoma: Response to radiotherapy. (24376934)
2010
27
Chemotherapy for Langerhans cell sarcoma. (19337819)
2009
28
Langerhans cell sarcoma involving gallbladder and peritoneal lymph nodes: a case report. (18805873)
2009
29
Primary cutaneous Langerhans cell sarcoma without Birbeck granules: indeterminate cell sarcoma? (18422973)
2008
30
ESHAP therapy effective in a patient with Langerhans cell sarcoma. (18415657)
2008
31
Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen. (18274862)
2008
32
Fine needle aspiration cytology of Langerhans cell sarcoma. (18205629)
2008
33
Leukemic transformation of Langerhans cell sarcoma. (18360746)
2008
34
Cutaneous Langerhans cell sarcoma: a case report and review of the literature. (17321988)
2007
35
Langerhans cell sarcoma in a patient who underwent transplantation. (17659009)
2007
36
Langerhans cell sarcoma. (16456323)
2006
37
Langerhans cell sarcoma arising from Langerhans cell histiocytosis: a case report. (16778410)
2006
38
Pulmonary manifestation of a Langerhans cell sarcoma: case report and review of the literature. (16328350)
2006
39
CD56/NCAM-positive Langerhans cell sarcoma: a clinicopathologic study of 4 cases. (15914364)
2005

Variations for Langerhans Cell Sarcoma

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Expression for genes affiliated with Langerhans Cell Sarcoma

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Search GEO for disease gene expression data for Langerhans Cell Sarcoma.

Pathways for genes affiliated with Langerhans Cell Sarcoma

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Compounds for genes affiliated with Langerhans Cell Sarcoma

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Sources:
45Novoseek
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Compounds related to Langerhans Cell Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1lipid459.1CD1A, S100B

GO Terms for genes affiliated with Langerhans Cell Sarcoma

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Products for genes affiliated with Langerhans Cell Sarcoma

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Sources for Langerhans Cell Sarcoma

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet