MCID: LNG004
MIFTS: 29

Langerhans Cell Sarcoma malady

Rare diseases, Blood diseases, Cancer diseases categories

Summaries for Langerhans Cell Sarcoma

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Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A histiocytic and dendritic cell cancer that derives from the lymph nodes, derives from the skin, derives from the liver, derives from the spleen and derives from bones.

MalaCards: Langerhans Cell Sarcoma, also known as malignant langerhans cell sarcoma, is related to sarcoma and histiocytosis. An important gene associated with Langerhans Cell Sarcoma is CD207 (CD207 molecule, langerin). The compound lipid have been mentioned in the context of this disorder. Affiliated tissues include bone, spleen and lung.

Wikipedia:66 Langerhans cell sarcoma is a form of malignant histiocytosis. It should not be confused with Langerhans... more...

Aliases & Classifications for Langerhans Cell Sarcoma

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 50Orphanet, 63UMLS, 36MeSH, 59SNOMED-CT, 41NCIt, 37MESH via Orphanet, 60SNOMED-CT via Orphanet, 27ICD10 via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

50
langerhans cell sarcoma:
Age of onset: Variable


Aliases & Descriptions:

langerhans cell sarcoma 9 44 11 50 63
malignant langerhans cell sarcoma 44


External Ids:

Disease Ontology9 DOID:7146
MeSH36 D054752
NCIt41 C6921
MESH via Orphanet37 D054752
SNOMED-CT59 128814006
SNOMED-CT via Orphanet60 128814006
ICD10 via Orphanet27 C96.4
UMLS via Orphanet64 C1260327

Related Diseases for Langerhans Cell Sarcoma

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Langerhans Cell Sarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1sarcoma31.2S100B, CD1A, CD207
2histiocytosis30.2CD1A, CD207
3leukemia10.4
4cervicitis10.3
5langerhans-cell histiocytosis10.2
6hairy cell leukemia10.2
7peritonitis10.2
8melanoma10.0S100B, CD1A
9ipex syndrome10.0S100B, CD207

Graphical network of diseases related to Langerhans Cell Sarcoma:



Diseases related to langerhans cell sarcoma

Symptoms for Langerhans Cell Sarcoma

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Drugs & Therapeutics for Langerhans Cell Sarcoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Langerhans Cell Sarcoma

Drug clinical trials:

Search ClinicalTrials for Langerhans Cell Sarcoma

Search NIH Clinical Center for Langerhans Cell Sarcoma

Search CenterWatch for Langerhans Cell Sarcoma

Genetic Tests for Langerhans Cell Sarcoma

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Anatomical Context for Langerhans Cell Sarcoma

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Sources:
34MalaCards
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MalaCards organs/tissues related to Langerhans Cell Sarcoma:

34
Bone, Spleen, Lung, Lymph node, Skin

Animal Models for Langerhans Cell Sarcoma or affiliated genes

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Publications for Langerhans Cell Sarcoma

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53PubMed
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Articles related to Langerhans Cell Sarcoma:

(show all 31)
idTitleAuthorsYear
1
Langerhans cell sarcoma: a case report. (23590692)
2013
2
Expression and anatomical distribution of TIM-containing molecules in Langerhans cell sarcoma. (23264111)
2013
3
Langerhans cell sarcoma: a case report and review of the literature. (23557341)
2013
4
Langerhans cell sarcoma in two young children: imaging findings on initial presentation and recurrence. (23690723)
2013
5
Langerhans cell sarcoma of the nasopharynx: a rare case. (24215052)
2013
6
Paraneoplastic disseminated lentigines heralding aggressive Langerhans cell sarcoma. (22992981)
2013
7
Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature. (23051626)
2013
8
Unusual cutaneous Langerhans cell sarcoma without extracutaneous involvement. (23388086)
2013
9
Langerhans Cell Sarcoma Arising from Chronic Lymphocytic Lymphoma/Small Lymphocytic Leukemia: Lineage Analysis and BRAF V600E Mutation Study. (23923114)
2013
10
Langerhans Cell Sarcoma in a Chronic Myelogenous Leukemia Patient Undergoing Imatinib Mesylate Therapy: A Case Study and Review of the Literature. (24008437)
2013
11
Langerhans cell sarcoma in the cervical lymph node: a case report and literature review. (23207655)
2013
12
Langerhans cell sarcoma in a patient with hairy cell leukemia: common clonal origin indicated by identical immunoglobulin gene rearrangements. (22616604)
2012
13
Multifocal Langerhans cell sarcoma involving epidermis: a case report and review. (22889043)
2012
14
The characteristic expression of B7-associated proteins in Langerhans cell sarcoma. (22305414)
2012
15
The characteristics of FDG PET/CT imaging in pulmonary Langerhans cell sarcoma. (22475903)
2012
16
Langerhans cell sarcoma with an aberrant cytoplasmic CD3 expression. (23006414)
2012
17
Langerhans cell sarcoma of the cervical lymph node: a case report and literature review. (20554413)
2010
18
Langerhans cell sarcoma: Response to radiotherapy. (24376934)
2010
19
Chemotherapy for Langerhans cell sarcoma. (19337819)
2009
20
Langerhans cell sarcoma involving gallbladder and peritoneal lymph nodes: a case report. (18805873)
2009
21
Primary cutaneous Langerhans cell sarcoma without Birbeck granules: indeterminate cell sarcoma? (18422973)
2008
22
ESHAP therapy effective in a patient with Langerhans cell sarcoma. (18415657)
2008
23
Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen. (18274862)
2008
24
Fine needle aspiration cytology of Langerhans cell sarcoma. (18205629)
2008
25
Leukemic transformation of Langerhans cell sarcoma. (18360746)
2008
26
Cutaneous Langerhans cell sarcoma: a case report and review of the literature. (17321988)
2007
27
Langerhans cell sarcoma in a patient who underwent transplantation. (17659009)
2007
28
Langerhans cell sarcoma. (16456323)
2006
29
Langerhans cell sarcoma arising from Langerhans cell histiocytosis: a case report. (16778410)
2006
30
Pulmonary manifestation of a Langerhans cell sarcoma: case report and review of the literature. (16328350)
2006
31
CD56/NCAM-positive Langerhans cell sarcoma: a clinicopathologic study of 4 cases. (15914364)
2005

Variations for Langerhans Cell Sarcoma

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Expression for genes affiliated with Langerhans Cell Sarcoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Langerhans Cell Sarcoma

Search GEO for disease gene expression data for Langerhans Cell Sarcoma.

Pathways for genes affiliated with Langerhans Cell Sarcoma

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Compounds for genes affiliated with Langerhans Cell Sarcoma

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46Novoseek
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Compounds related to Langerhans Cell Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1lipid469.1CD1A, S100B

GO Terms for genes affiliated with Langerhans Cell Sarcoma

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Products for genes affiliated with Langerhans Cell Sarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Langerhans Cell Sarcoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet