MCID: LNG004
MIFTS: 30

Langerhans Cell Sarcoma malady

Rare diseases, Blood diseases, Cancer diseases categories
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Summaries for Langerhans Cell Sarcoma

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Disease Ontology:8 A histiocytic and dendritic cell cancer that derives from the lymph nodes, derives from the skin, derives from the liver, derives from the spleen and derives from bones.

MalaCards based summary: Langerhans Cell Sarcoma, also known as malignant langerhans cell sarcoma, is related to sarcoma and langerhans-cell histiocytosis. An important gene associated with Langerhans Cell Sarcoma is CD207 (CD207 molecule, langerin). The compound lipid have been mentioned in the context of this disorder. Affiliated tissues include bone, spleen and lung.

Wikipedia:65 Langerhans cell sarcoma is a form of malignant histiocytosis. It should not be confused with Langerhans... more...

Aliases & Classifications for Langerhans Cell Sarcoma

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 62UMLS, 34MeSH, 57SNOMED-CT, 39NCIt, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Langerhans Cell Sarcoma, Aliases & Descriptions:

Name: Langerhans Cell Sarcoma 8 42 10 48 62
 
Malignant Langerhans Cell Sarcoma 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

48
langerhans cell sarcoma:
Age of onset: Variable


External Ids:

Disease Ontology8 DOID:7146
MeSH34 D054752
NCIt39 C6921
SNOMED-CT57 128814006
MESH via Orphanet35 D054752
ICD10 via Orphanet26 C96.4
UMLS via Orphanet63 C1260327

Related Diseases for Langerhans Cell Sarcoma

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Diseases related to Langerhans Cell Sarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1sarcoma30.8S100B, CD1A, CD207
2langerhans-cell histiocytosis30.0CD1A, CD207
3histiocytosis29.7S100B, CD207, CD1A
4leukemia10.4
5cervicitis10.3
6hairy cell leukemia10.2
7peritonitis10.2
8dendritic cell tumor10.2
9melanoma9.9S100B, CD1A
10ipex syndrome9.8S100B, CD207

Graphical network of diseases related to Langerhans Cell Sarcoma:



Diseases related to langerhans cell sarcoma

Symptoms for Langerhans Cell Sarcoma

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Drugs & Therapeutics for Langerhans Cell Sarcoma

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Drug clinical trials:

Search ClinicalTrials for Langerhans Cell Sarcoma

Search NIH Clinical Center for Langerhans Cell Sarcoma

Genetic Tests for Langerhans Cell Sarcoma

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Anatomical Context for Langerhans Cell Sarcoma

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MalaCards organs/tissues related to Langerhans Cell Sarcoma:

32
Bone, Spleen, Lung, Lymph node, Skin

Animal Models for Langerhans Cell Sarcoma or affiliated genes

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Publications for Langerhans Cell Sarcoma

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Articles related to Langerhans Cell Sarcoma:

(show all 36)
idTitleAuthorsYear
1
High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. (24834110)
2014
2
Clinical experience of bendamustine for adult Langerhans cell sarcoma. (24881923)
2014
3
Rare case of Langerhans cell sarcoma with cutaneous manifestation arising on the inguinal region. (25387842)
2014
4
Langerhans cell sarcoma: case report and review of world literature. (24942035)
2014
5
A case of an adult Langerhans cell sarcoma. (25312302)
2014
6
Cutaneous Langerhans cell sarcoma relapsing systemically: Complete remission with the EPIG regimen. (25186787)
2014
7
Langerhans cell sarcoma: a case report. (23590692)
2013
8
Expression and anatomical distribution of TIM-containing molecules in Langerhans cell sarcoma. (23264111)
2013
9
Langerhans cell sarcoma: a case report and review of the literature. (23557341)
2013
10
Langerhans cell sarcoma in two young children: imaging findings on initial presentation and recurrence. (23690723)
2013
11
Langerhans cell sarcoma of the nasopharynx: a rare case. (24215052)
2013
12
Paraneoplastic disseminated lentigines heralding aggressive Langerhans cell sarcoma. (22992981)
2013
13
Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature. (23051626)
2013
14
Unusual cutaneous Langerhans cell sarcoma without extracutaneous involvement. (23388086)
2013
15
Langerhans Cell Sarcoma Arising from Chronic Lymphocytic Lymphoma/Small Lymphocytic Leukemia: Lineage Analysis and BRAF V600E Mutation Study. (23923114)
2013
16
Langerhans Cell Sarcoma in a Chronic Myelogenous Leukemia Patient Undergoing Imatinib Mesylate Therapy: A Case Study and Review of the Literature. (24008437)
2013
17
Langerhans cell sarcoma in the cervical lymph node: a case report and literature review. (23207655)
2013
18
Langerhans cell sarcoma in a patient with hairy cell leukemia: common clonal origin indicated by identical immunoglobulin gene rearrangements. (22616604)
2012
19
Multifocal Langerhans cell sarcoma involving epidermis: a case report and review. (22889043)
2012
20
The characteristic expression of B7-associated proteins in Langerhans cell sarcoma. (22305414)
2012
21
The characteristics of FDG PET/CT imaging in pulmonary Langerhans cell sarcoma. (22475903)
2012
22
Langerhans cell sarcoma with an aberrant cytoplasmic CD3 expression. (23006414)
2012
23
Langerhans cell sarcoma of the cervical lymph node: a case report and literature review. (20554413)
2010
24
Langerhans cell sarcoma: Response to radiotherapy. (24376934)
2010
25
Chemotherapy for Langerhans cell sarcoma. (19337819)
2009
26
Langerhans cell sarcoma involving gallbladder and peritoneal lymph nodes: a case report. (18805873)
2009
27
Primary cutaneous Langerhans cell sarcoma without Birbeck granules: indeterminate cell sarcoma? (18422973)
2008
28
ESHAP therapy effective in a patient with Langerhans cell sarcoma. (18415657)
2008
29
Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen. (18274862)
2008
30
Fine needle aspiration cytology of Langerhans cell sarcoma. (18205629)
2008
31
Leukemic transformation of Langerhans cell sarcoma. (18360746)
2008
32
Cutaneous Langerhans cell sarcoma: a case report and review of the literature. (17321988)
2007
33
Langerhans cell sarcoma in a patient who underwent transplantation. (17659009)
2007
34
Langerhans cell sarcoma. (16456323)
2006
35
Langerhans cell sarcoma arising from Langerhans cell histiocytosis: a case report. (16778410)
2006
36
Pulmonary manifestation of a Langerhans cell sarcoma: case report and review of the literature. (16328350)
2006

Variations for Langerhans Cell Sarcoma

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Expression for genes affiliated with Langerhans Cell Sarcoma

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Expression patterns in normal tissues for genes affiliated with Langerhans Cell Sarcoma

Search GEO for disease gene expression data for Langerhans Cell Sarcoma.

Pathways for genes affiliated with Langerhans Cell Sarcoma

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Compounds for genes affiliated with Langerhans Cell Sarcoma

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Sources:
44Novoseek
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Compounds related to Langerhans Cell Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1lipid449.1CD1A, S100B

GO Terms for genes affiliated with Langerhans Cell Sarcoma

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Products for genes affiliated with Langerhans Cell Sarcoma

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  • Antibodies
  • Proteins
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Sources for Langerhans Cell Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet