MCID: LRY018
MIFTS: 57

Laryngeal Squamous Cell Carcinoma malady

Cancer diseases, Skin diseases, Oral diseases categories
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Summaries for Laryngeal Squamous Cell Carcinoma

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Disease Ontology:8 A laryngeal carcinoma that has material basis in squamous cells.

MalaCards based summary: Laryngeal Squamous Cell Carcinoma, also known as epidermoid carcinoma of the larynx, is related to papilloma and lung adenocarcinoma. An important gene associated with Laryngeal Squamous Cell Carcinoma is GSTM3 (glutathione S-transferase mu 3 (brain)), and among its related pathways are IL-2 Gene Expression in Activated and Quiescent T-Cells and FoxO signaling pathway. The compounds drugs for treatment of tuberculosis and p00001 have been mentioned in the context of this disorder. Affiliated tissues include lymph node, endothelial and thyroid, and related mouse phenotypes are digestive/alimentary and embryogenesis.

Aliases & Classifications for Laryngeal Squamous Cell Carcinoma

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Laryngeal Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Laryngeal Squamous Cell Carcinoma 8 10 44 62
Epidermoid Carcinoma of the Larynx 8 62
 
Squamous Cell Carcinoma of Larynx 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases, Oral diseases


External Ids:

Disease Ontology8 DOID:2876
SNOMED-CT57 405822008
NCIt39 C4044

Related Diseases for Laryngeal Squamous Cell Carcinoma

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Diseases related to Laryngeal Squamous Cell Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1papilloma31.5CDKN2B, CDKN2A
2lung adenocarcinoma29.6CDKN2A, GSTT1, GSTM1, BIRC5, CCND1, TERT
3retinoblastoma29.3CDKN2B, CDKN2A, NME1, BIRC5, CCND1, CCNA2
4adenocarcinoma27.9CTSD, CDKN2A, EIF4E, NME1, GSTT1, GSTM1
5laryngitis11.6
6endotheliitis10.7
7cervicitis10.6
8thyroiditis10.6
9hypoxia10.6
10neuronal ceroid-lipofuscinoses10.5CTSD
11gliomatosis cerebri10.4PTEN
12pharyngitis10.4
13nasopharyngitis10.4
14laryngeal carcinoma10.4
15papillary thyroid carcinoma10.4
16skin melanoma10.4CDKN2B, NME1
17esophageal cancer10.3CDKN2A, CCND1
18ependymoma10.3CDKN2B, MKI67
19burkitt's lymphoma10.3CDKN2B, CCND1
20malignant mesothelioma10.3CDKN2B, CDKN2A, NAT2
21parathyroid carcinoma10.3CCND1, MKI67
22cataract10.3GSTT1, GSTM3, NAT2
23hodgkin's lymphoma10.3
24sarcocystosis10.3
25conjunctivitis10.3
26epidermolysis bullosa10.3
27histoplasmosis10.3
28lipoma10.3
29kindler syndrome10.3
30familial colorectal cancer10.3CDKN2A, PTEN
31breast ductal carcinoma10.2CTSD, NME1
32bladder transitional cell carcinoma10.2CDKN2B, BIRC5, MKI67
33familial adenomatous polyposis10.2BIRC5, CCND1, NAT2
34cervical adenocarcinoma10.2CDKN2A, NME1
35oligodendroglioma10.2CDKN2B, CDKN2A, PTEN
36anaplastic oligodendroglioma10.2CDKN2B, CDKN2A, PTEN
37adenosquamous carcinoma10.2CTSD, NME1
38keratoacanthoma10.2NME1, MKI67
39rectal neoplasm10.2BIRC5, NAT2
40breast cancer10.2CTSD, CCND1, AURKA
41hematologic cancer10.2CDKN2B, BIRC5, CCNA2
42phyllode tumor10.2CCNA2, MKI67
43follicular adenoma10.2CDKN2B, NME1, PTEN
44gastritis10.2GSTT1, TERT
45follicular thyroid carcinoma10.2NME1, PTEN
46brain cancer10.2GSTT1, GSTM1
47asbestosis10.1GSTT1, GSTM1
48chronic lymphocytic leukemia10.1BIRC5, CCND1, CCNA2
49breast fibroadenoma10.1CTSD, NME1, MKI67
50cholangiocarcinoma10.1EIF4E, NAT2, TERT

Graphical network of the top 20 diseases related to Laryngeal Squamous Cell Carcinoma:



Diseases related to laryngeal squamous cell carcinoma

Symptoms for Laryngeal Squamous Cell Carcinoma

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Drugs & Therapeutics for Laryngeal Squamous Cell Carcinoma

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Drug clinical trials:

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Genetic Tests for Laryngeal Squamous Cell Carcinoma

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Anatomical Context for Laryngeal Squamous Cell Carcinoma

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MalaCards organs/tissues related to Laryngeal Squamous Cell Carcinoma:

32
Lymph node, Endothelial, Thyroid, Skin, T cells, Lung, Pituitary

Animal Models for Laryngeal Squamous Cell Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Laryngeal Squamous Cell Carcinoma:

36 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4CTSD, CDKN2A, CCND1, PTEN, TERT
2MP:00053808.2AURKA, PTEN, CCNA2, BIRC5, NME1, CDKN2A
3MP:00053898.1TERT, PTEN, NAT2, CCND1, CDKN2A, CDKN2B
4MP:00053797.9TERT, PTEN, CCND1, NME1, CDKN2A, CDKN2B
5MP:00020067.8CDKN2B, TERT, AURKA, PTEN, CCND1, NME1
6MP:00053877.4TERT, PTEN, CCNA2, CCND1, BIRC5, CDKN2A
7MP:00053977.2TERT, PTEN, CCNA2, CCND1, BIRC5, NME1
8MP:00107686.9TERT, AURKA, PTEN, CCNA2, CCND1, BIRC5
9MP:00036316.8TERT, PTEN, CCND1, GSTM1, NME1, CDKN2A
10MP:00053766.3CCND1, NAT2, PTEN, TERT, BIRC5, GSTM1
11MP:00053846.3TERT, AURKA, PTEN, CCNA2, CCND1, BIRC5

Publications for Laryngeal Squamous Cell Carcinoma

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Articles related to Laryngeal Squamous Cell Carcinoma:

(show top 50)    (show all 579)
idTitleAuthorsYear
1
LOH Detected by Microsatellite Markers Reveals the Clonal Origin of Recurrent Laryngeal Squamous Cell Carcinoma. (25365429)
2014
2
miR-375 suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal squamous cell carcinoma. (25184138)
2014
3
The Efficacy of 18F-FDG PET/CT Imaging for Extracapsular spread of the laryngeal squamous cell carcinoma. (25327765)
2014
4
Identification of cancer stem-like side population cells in purified primary cultured human laryngeal squamous cell carcinoma epithelia. (23776540)
2013
5
Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma. (22605671)
2013
6
Heterogeneity of 11q13 region rearrangements in laryngeal squamous cell carcinoma analyzed by microarray platforms and fluorescence in situ hybridization. (23652995)
2013
7
Significance of MDM2-309 Polymorphisms and Induced Corresponding Plasma MDM2 Levels in Susceptibility to Laryngeal Squamous Cell Carcinoma. (24325471)
2013
8
High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma. (23835793)
2013
9
Expression and clinicopathological significance of foxM1 gene in laryngeal squamous cell carcinoma]. (23285957)
2012
10
Cigarette smoking and alcohol ingestion as risk factors for laryngeal squamous cell carcinoma at kenyatta national hospital, kenya. (24179405)
2012
11
Expression of VEGF-C/VEGFR-3 in human laryngeal squamous cell carcinomas and its significance for lymphatic metastasis. (22502683)
2012
12
The cadherin-catenin complex in laryngeal squamous cell carcinoma. (22197995)
2012
13
The expression and relationship of CXCR4 and microvessel density in laryngeal squamous cell carcinoma]. (21553525)
2011
14
The involvement of CHD5 hypermethylation in laryngeal squamous cell carcinoma. (21636313)
2011
15
Aurora B kinase expression in laryngeal squamous cell carcinoma and its prognostic implications. (21299608)
2011
16
Podoplanin expression in the development and progression of laryngeal squamous cell carcinomas. (20196862)
2010
17
Study of mRNA expression level and hypermethylation of CHFR promoter in the laryngeal squamous cell carcinoma tissue]. (20942233)
2010
18
Silencing STAT3 with short hairpin RNA enhances radiosensitivity of human laryngeal squamous cell carcinoma xenografts in vivo. (22993624)
2010
19
Assessment of disease-free survival in patients with laryngeal squamous cell carcinoma treated with radiotherapy associated or not with chemotherapy. (20549084)
2010
20
The expression of hepatocyte growth factor and heparanase in laryngeal squamous cell carcinoma and its clinical significance]. (19452723)
2009
21
Expression and pathobiological significance of Col I, Col IV and Fn in laryngeal squamous cell carcinomas]. (20359090)
2009
22
Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. (19513509)
2009
23
Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. (18604514)
2008
24
Expression of Livin in laryngeal squamous cell carcinoma and relationship with bFGF]. (18476630)
2008
25
The mutation and expression of MUS81 gene in laryngeal squamous cell carcinoma]. (18841572)
2008
26
Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of laryngeal squamous cell carcinoma]. (18826096)
2008
27
Expression of cyclin G1 in laryngeal squamous cell carcinoma and its clinicopathologic significance]. (18788592)
2008
28
The relationship between the activation of ERK and the up-regulation of uPA in laryngeal squamous cell carcinoma]. (17634019)
2007
29
Combined p14ARF and antisense EGFR potentiate the efficacy of adenovirus-mediated gene therapy in laryngeal squamous cell carcinoma (LSCC). (17328665)
2007
30
The expressions and significance of CK2 in normal laryngeal mucosa, laryngeal precancerosis and laryngeal squamous cell carcinoma]. (18062282)
2007
31
Clinical significance and expression of FLIP and PTEN protein in laryngeal squamous cell carcinoma]. (17441421)
2007
32
Fas expression is associated with a better prognosis in laryngeal squamous cell carcinoma. (18225575)
2007
33
The expression of tumor necrosis factor related apoptosis induce ligand in human laryngeal squamous cell carcinoma]. (17357513)
2006
34
Expression of telomerase reverse transcriptase and its relationship with expression of c-myc in laryngeal squamous cell carcinomas]. (17219990)
2006
35
Multivariate survival analysis in patient with laryngeal squamous cell carcinomas]. (17017186)
2006
36
Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness. (16299231)
2005
37
Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas. (15671554)
2005
38
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. (15746850)
2005
39
Laryngeal squamous cell carcinoma with ectopic production of granulocyte colony-stimulating factor and parathyroid hormone-related protein. (15990969)
2005
40
Combination of adenovirus p16(INK4A) gene therapy and ionizing radiation for laryngeal squamous cell carcinoma]. (15071918)
2004
41
Expression of VEGF-C and VEGFR-3 in human laryngeal squamous cell carcinomas and cervical metastatic lymph node tissues]. (15715411)
2004
42
Expression and significance of PTEN and caspase-3 in laryngeal squamous cell carcinoma]. (15831044)
2004
43
Gene expression of matrix metalloproteinase 14 in laryngeal squamous cell carcinoma]. (15563089)
2004
44
Correlation of FHIT expression to cell proliferation and metastasis of laryngeal squamous cell carcinoma]. (15522186)
2004
45
p63 in laryngeal squamous cell carcinoma: evidence for a role of TA-p63 down-regulation in tumorigenesis and lack of prognostic implications of p63 immunoreactivity. (12379767)
2002
46
Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas. (11911285)
2001
47
The study of p16 gene mutation and methylation in laryngeal squamous cell carcinoma]. (12768709)
2000
48
Immunohistochemical study of Cath-D and CD44 in laryngeal squamous cell carcinomas]. (11189153)
1998
49
Microvessel count is predictive of patients' survival in laryngeal squamous-cell carcinoma. (8900379)
1996
50
Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. (8883413)
1996

Variations for Laryngeal Squamous Cell Carcinoma

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Expression for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Expression patterns in normal tissues for genes affiliated with Laryngeal Squamous Cell Carcinoma

Search GEO for disease gene expression data for Laryngeal Squamous Cell Carcinoma.

Pathways for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Pathways related to Laryngeal Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6CCNA2, CCND1
2
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
9.4PTEN, CCND1, CDKN2B
39.4CDKN2B, PTEN, CCND1
4
Show member pathways
Signal transduction PTEN pathway60
9.4PTEN, CCND1, BIRC5
59.4PTEN, CCND1, AURKA
69.3GSTM1, GSTT1
79.3GSTM1, GSTT1
89.3CDKN2A, CCND1, PTEN
9
Show member pathways
DNA damage response37
9.3CCND1, CDKN2A, PTEN
10
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
9.3CCND1, PTEN, CDKN2A
11
Show member pathways
glutathione-mediated detoxification I37
glutathione redox reactions I37
glutathione redox reactions II37
4-hydroxy-2-nonenal detoxification37
Glutathione metabolism60
Glutathione metabolism37
9.1GSTM1, GSTT1, GSTM3
12
Show member pathways
Signaling Pathways in Glioblastoma37
9.1PTEN, CCND1, CDKN2A, CDKN2B
13
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation60
9.0CDKN2A, CDKN2B, CCND1, CCNA2
14
Show member pathways
9.0CDKN2B, CCNA2, CCND1, CDKN2A
15
Show member pathways
9.0CDKN2B, CCND1, CDKN2A, CCNA2
169.0CDKN2B, CCNA2, CCND1, CDKN2A
17
Show member pathways
Cell cycle37
9.0CCND1, CDKN2A, CCNA2, CDKN2B
188.9BIRC5, EIF4E, TERT, NME1
198.9CDKN2B, CDKN2A, TERT, CCND1
20
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
8.9BIRC5, CCND1, CCNA2, PTEN
21
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.9CCND1, BIRC5, CCNA2, PTEN
22
Show member pathways
8.8GSTM1, NAT2, GSTT1, GSTM3
23
Show member pathways
8.8GSTM1, GSTM3, NAT2, GSTT1
248.8BIRC5, CCND1, CDKN2A, CDKN2B, PTEN
25
Show member pathways
8.8CDKN2B, CCNA2, BIRC5, CDKN2A, CCND1
268.5PTEN, CDKN2B, CCNA2, CCND1, NME1
27
Show member pathways
8.5CDKN2A, MKI67, AURKA, CCNA2, CCND1
28
Show member pathways
8.0PTEN, NME1, GSTT1, GSTM1, GSTM3, NAT2
29
Show member pathways
7.9CDKN2B, TERT, AURKA, CCNA2, CCND1, BIRC5

Compounds for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Compounds related to Laryngeal Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 210)
idCompoundScoreTop Affiliating Genes
1drugs for treatment of tuberculosis509.4GSTT1, NAT2, GSTM1
2p00001449.2CCND1, CDKN2A, BIRC5, MKI67
3crcs449.0CDKN2A, NME1, BIRC5, CCND1, PTEN
4isoniazid44 50 1111.0NAT2, GSTM1, CDKN2A, GSTT1
5aflatoxin b144 2410.0NAT2, GSTM1, GSTT1, CDKN2A
6gsts448.8NAT2, GSTT1, GSTM1, GSTM3
7adriamycin448.7TERT, CTSD, CDKN2A, BIRC5, CCND1
8chi 2448.7NME1, MKI67, GSTT1, GSTM1
9acetone448.7MKI67, CCND1, GSTM1, GSTT1
10mg 13244 619.6CCNA2, CDKN2A, EIF4E, BIRC5, PTEN, CCND1
11p003448.5CTSD, CDKN2B, GSTT1, GSTM1, MKI67
12agar448.5CCND1, PTEN, EIF4E, CDKN2A, CTSD, NME1
13depsipeptide448.3TERT, CCNA2, CDKN2A, CCND1
14butyrate448.3CDKN2A, CCNA2, CCND1, TERT, CTSD, BIRC5
15tamoxifen44 50 28 1111.3MKI67, PTEN, CCNA2, BIRC5, CCND1, CTSD
16tgf beta1448.3MKI67, PTEN, CDKN2B, CCND1, CCNA2
17p002448.2GSTM1, CTSD, NME1, BIRC5, MKI67, GSTT1
18folate448.2MKI67, NAT2, GSTM1, CCND1, GSTT1, CDKN2A
19pd 98,059448.1PTEN, CDKN2B, CCND1, TERT, BIRC5, EIF4E
20rapamycin448.1CCNA2, PTEN, TERT, EIF4E, BIRC5, CCND1
21estradiol44 24 1110.1BIRC5, CCND1, CCNA2, PTEN, MKI67, CTSD
22ly294002448.1EIF4E, PTEN, TERT, BIRC5, CCND1, CCNA2
23genistein44 28 61 2 24 1112.9TERT, PTEN, CCNA2, BIRC5, CDKN2A, CTSD
24cyclophosphamide44 50 119.9GSTT1, NAT2, MKI67, CTSD, PTEN, GSTM1
25arsenite44 248.9CDKN2B, EIF4E, PTEN, TERT, BIRC5, CCND1
26cycloheximide447.8EIF4E, MKI67, CTSD, PTEN, BIRC5, CCND1
27thymidine44 248.8NME1, BIRC5, CCND1, CTSD, CCNA2, TERT
28etoposide44 50 61 1110.7CCNA2, NME1, TERT, CTSD, EIF4E, GSTT1
29aspartate447.7CTSD, PTEN, CCNA2, GSTM1, NME1, CDKN2A
30vincristine44 50 119.6BIRC5, CDKN2A, CCND1, PTEN, MKI67, GSTM1
31methotrexate50 44 119.6CDKN2B, MKI67, CCND1, CCNA2, CDKN2A, BIRC5
32thymidylate447.4CDKN2A, CCNA2, CCND1, BIRC5, GSTM1, MKI67
33paclitaxel44 50 119.3MKI67, AURKA, BIRC5, CTSD, CDKN2A, TERT
34h2o2447.3CCNA2, GSTM1, CTSD, PTEN, TERT, EIF4E
35progesterone44 28 61 24 1111.2NME1, CCNA2, CTSD, MKI67, CDKN2A, BIRC5
36cysteine447.1NME1, GSTM1, NAT2, CTSD, PTEN, TERT
37steroid447.1CDKN2A, CCNA2, MKI67, EIF4E, NME1, GSTT1
38paraffin447.1CDKN2A, CTSD, NME1, BIRC5, CCNA2, PTEN
39oligonucleotide447.1NAT2, CCND1, PTEN, CCNA2, BIRC5, GSTT1
40threonine447.0PTEN, MKI67, AURKA, CDKN2B, CDKN2A, EIF4E
41nitric oxide44 24 118.9EIF4E, NME1, TERT, PTEN, NAT2, CCNA2
42vegf446.8CTSD, BIRC5, PTEN, CCNA2, CCND1, MKI67
435fluorouracil446.7TERT, MKI67, PTEN, CCNA2, BIRC5, GSTM1
44testosterone44 61 24 119.7CCND1, CCNA2, TERT, PTEN, MKI67, BIRC5
45retinoic acid44 247.6NME1, BIRC5, MKI67, CCNA2, CCND1, PTEN
46doxorubicin44 50 118.4CTSD, CDKN2A, TERT, MKI67, PTEN, CCNA2
47serine446.3BIRC5, CCND1, CCNA2, NME1, EIF4E, CDKN2A
48oxygen44 247.3PTEN, CCNA2, MKI67, GSTM1, GSTT1, EIF4E
49cisplatin44 50 61 118.2CCND1, PTEN, MKI67, TERT, CDKN2A, CTSD
50estrogen444.9CCND1, PTEN, CTSD, CDKN2B, TERT, AURKA

GO Terms for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Cellular components related to Laryngeal Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleolusGO:0057307.9CDKN2A, CCND1, PTEN, MKI67, TERT, CDKN2B
2nucleusGO:0056346.8PTEN, CCNA2, CCND1, BIRC5, NME1, CDKN2A
3cytosolGO:0058296.3AURKA, CDKN2B, CDKN2A, EIF4E, NME1, GSTT1
4cytoplasmGO:0057375.7GSTM3, BIRC5, CCNA2, PTEN, MKI67, TERT

Biological processes related to Laryngeal Squamous Cell Carcinoma according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of mitotic cell cycleGO:04593110.0EIF4E, BIRC5
2regulation of G2/M transition of mitotic cell cycleGO:0103899.8CCNA2, CDKN2A
3regulation of protein stabilityGO:0316479.7CDKN2A, PTEN, AURKA
4nitrobenzene metabolic processGO:0189169.7GSTM1, GSTM3
5cellular detoxification of nitrogen compoundGO:0704589.7GSTM1, GSTM3
6negative regulation of G1/S transition of mitotic cell cycleGO:20001349.7CDKN2B, PTEN
7response to organic cyclic compoundGO:0140709.7CDKN2B, GSTT1, MKI67
8xenobiotic catabolic processGO:0421789.6GSTM1, GSTM3
9replicative senescenceGO:0903999.6TERT, CDKN2A
10negative regulation of phosphorylationGO:0423269.6CDKN2B, CDKN2A
11G2/M transition of mitotic cell cycleGO:0000869.5AURKA, CCNA2, BIRC5, CDKN2B
12G1/S transition of mitotic cell cycleGO:0000829.5CCND1, EIF4E, CDKN2A
13regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.5CDKN2B, CCNA2, PTEN
14glutathione derivative biosynthetic processGO:19016879.4GSTM3, GSTM1, GSTT1
15glutathione metabolic processGO:0067499.4GSTM3, GSTM1, GSTT1
16organ regenerationGO:0311009.3MKI67, CCNA2, CCND1
17xenobiotic metabolic processGO:0068059.1GSTT1, GSTM1, GSTM3, NAT2
18negative regulation of cell proliferationGO:0082859.1CDKN2B, CDKN2A, NME1, PTEN
19mitotic cell cycleGO:0002788.8CDKN2B, CDKN2A, BIRC5, CCND1, CCNA2, AURKA
20small molecule metabolic processGO:0442818.1NME1, GSTT1, GSTM1, GSTM3, NAT2, PTEN

Molecular functions related to Laryngeal Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.9CDKN2B, CDKN2A
2glutathione bindingGO:0432959.1GSTM1, GSTM3
3glutathione transferase activityGO:0043649.0GSTM3, GSTM1, GSTT1
4enzyme bindingGO:0198998.4PTEN, CCND1, BIRC5, GSTM3, GSTM1
5protein kinase bindingGO:0199018.0CDKN2B, CDKN2A, NME1, CCND1, CCNA2, PTEN
6protein bindingGO:0055155.9TERT, AURKA, MKI67, PTEN, CCNA2, CCND1

Products for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Sources for Laryngeal Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet