MCID: LRY018
MIFTS: 49

Laryngeal Squamous Cell Carcinoma malady

Skin diseases, Oral diseases, Cancer diseases categories

Aliases & Classifications for Laryngeal Squamous Cell Carcinoma

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Laryngeal Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Laryngeal Squamous Cell Carcinoma 9 11 43 60
Epidermoid Carcinoma of the Larynx 9
 
Squamous Cell Carcinoma of Larynx 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases, Oral diseases


External Ids:

Disease Ontology9 DOID:2876
SNOMED-CT55 405822008
NCIt38 C4044

Summaries for Laryngeal Squamous Cell Carcinoma

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Disease Ontology:9 A laryngeal carcinoma that has material basis in squamous cells.

MalaCards based summary: Laryngeal Squamous Cell Carcinoma, also known as epidermoid carcinoma of the larynx, is related to papilloma and nasopharyngeal carcinoma. An important gene associated with Laryngeal Squamous Cell Carcinoma is GSTM3 (glutathione S-transferase mu 3 (brain)), and among its related pathways are IL-2 Gene Expression in Activated and Quiescent T-Cells and Small cell lung cancer. The compounds drugs for treatment of tuberculosis and p00001 have been mentioned in the context of this disorder. Affiliated tissues include lymph node, endothelial and thyroid, and related mouse phenotypes are digestive/alimentary and embryogenesis.

Related Diseases for Laryngeal Squamous Cell Carcinoma

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Diseases related to Laryngeal Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 113)
idRelated DiseaseScoreTop Affiliating Genes
1papilloma31.5CDKN2B, CDKN2A
2nasopharyngeal carcinoma29.6CDKN2A, NME1, GSTT1, GSTM1, NAT2, TERT
3retinoblastoma29.3CDKN2B, CDKN2A, NME1, BIRC5, CCND1, CCNA2
4laryngeal carcinoma29.0CTSD, NME1, GSTT1, GSTM1, GSTM3, CCNA2
5adenocarcinoma27.8CTSD, CDKN2A, EIF4E, NME1, GSTT1, GSTM1
6laryngitis11.7
7endotheliitis10.7
8cervicitis10.6
9thyroiditis10.6
10hypoxia10.6
11neuronal ceroid-lipofuscinoses10.5CTSD
12pharyngitis10.4
13nasopharyngitis10.4
14gliomatosis cerebri10.4PTEN
15skin melanoma10.4CDKN2B, NME1
16tonsil squamous cell carcinoma10.3CDKN2A, CCND1
17ependymoma10.3CDKN2B, MKI67
18burkitt lymphoma10.3CDKN2B, CCND1
19mesothelioma, somatic10.3CDKN2B, CDKN2A, NAT2
20parathyroid carcinoma10.3CCND1, MKI67
21kindler syndrome10.3
22lipoma10.3
23hodgkin lymphoma10.3
24sarcocystosis10.3
25conjunctivitis10.3
26epidermolysis bullosa10.3
27histoplasmosis10.3
28cataract10.3GSTT1, GSTM3, NAT2
29breast ductal carcinoma10.2CTSD, NME1
30bladder transitional cell carcinoma10.2CDKN2B, BIRC5, MKI67
31adenomatous polyposis coli10.2BIRC5, CCND1, NAT2
32cervical adenocarcinoma10.2CDKN2A, NME1
33oligodendroglioma10.2CDKN2B, CDKN2A, PTEN
34anaplastic oligodendroglioma10.2CDKN2B, CDKN2A, PTEN
35adenosquamous carcinoma10.2CTSD, NME1
36keratoacanthoma10.2NME1, MKI67
37rectal neoplasm10.2BIRC5, NAT2
38breast cancer10.2CTSD, CCND1, AURKA
39hematologic cancer10.2CDKN2B, BIRC5, CCNA2
40benign breast phyllodes tumor10.2CCNA2, MKI67
41follicular adenoma10.2CDKN2B, NME1, PTEN
42gastritis10.2GSTT1, TERT
43thyroid carcinoma, follicular10.2NME1, PTEN
44brain cancer10.1GSTT1, GSTM1
45asbestosis10.1GSTT1, GSTM1
46chronic lymphocytic leukemia10.1BIRC5, CCND1, CCNA2
47breast fibroadenoma10.1CTSD, NME1, MKI67
48cholangiocarcinoma10.1EIF4E, NAT2, TERT
49cervical squamous cell carcinoma10.1CDKN2A, MKI67
50barrett esophagus/esophageal adenocarcinoma10.1CDKN2A, CCND1, MKI67

Graphical network of the top 20 diseases related to Laryngeal Squamous Cell Carcinoma:



Diseases related to laryngeal squamous cell carcinoma

Symptoms for Laryngeal Squamous Cell Carcinoma

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Drugs & Therapeutics for Laryngeal Squamous Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Laryngeal Squamous Cell Carcinoma

Search NIH Clinical Center for Laryngeal Squamous Cell Carcinoma

Genetic Tests for Laryngeal Squamous Cell Carcinoma

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Anatomical Context for Laryngeal Squamous Cell Carcinoma

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MalaCards organs/tissues related to Laryngeal Squamous Cell Carcinoma:

31
Lymph node, Endothelial, Thyroid, Skin, T cells, Lung, Pituitary

Animal Models for Laryngeal Squamous Cell Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Laryngeal Squamous Cell Carcinoma:

35 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4CTSD, CDKN2A, CCND1, PTEN, TERT
2MP:00053808.2AURKA, PTEN, CCNA2, BIRC5, NME1, CDKN2A
3MP:00053898.1TERT, PTEN, NAT2, CCND1, CDKN2A, CDKN2B
4MP:00053797.9TERT, PTEN, CCND1, NME1, CDKN2A, CDKN2B
5MP:00020067.8CDKN2B, TERT, AURKA, PTEN, CCND1, NME1
6MP:00053877.4TERT, PTEN, CCNA2, CCND1, BIRC5, CDKN2A
7MP:00053977.2TERT, PTEN, CCNA2, CCND1, BIRC5, NME1
8MP:00107686.9TERT, AURKA, PTEN, CCNA2, CCND1, BIRC5
9MP:00036316.8TERT, PTEN, CCND1, GSTM1, NME1, CDKN2A
10MP:00053766.3CCND1, NAT2, PTEN, TERT, BIRC5, GSTM1
11MP:00053846.3TERT, AURKA, PTEN, CCNA2, CCND1, BIRC5

Publications for Laryngeal Squamous Cell Carcinoma

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Articles related to Laryngeal Squamous Cell Carcinoma:

(show top 50)    (show all 599)
idTitleAuthorsYear
1
High microRNA-23a expression in laryngeal squamous cell carcinoma is associated with poor patient prognosis. (25879432)
2015
2
Expression of CBY and methylation of CBY at promoter region in human laryngeal squamous cell carcinoma. (25838250)
2015
3
Association of cagA Positive Helicobacter pylori Infection and Laryngeal Squamous Cell Carcinoma: A PCR Approach. (25621254)
2015
4
LOH Detected by Microsatellite Markers Reveals the Clonal Origin of Recurrent Laryngeal Squamous Cell Carcinoma. (25365429)
2014
5
miR-375 suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal squamous cell carcinoma. (25184138)
2014
6
Identification of cancer stem-like side population cells in purified primary cultured human laryngeal squamous cell carcinoma epithelia. (23776540)
2013
7
Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma. (22605671)
2013
8
Heterogeneity of 11q13 region rearrangements in laryngeal squamous cell carcinoma analyzed by microarray platforms and fluorescence in situ hybridization. (23652995)
2013
9
Significance of MDM2-309 Polymorphisms and Induced Corresponding Plasma MDM2 Levels in Susceptibility to Laryngeal Squamous Cell Carcinoma. (24325471)
2013
10
High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma. (23835793)
2013
11
Expression and clinicopathological significance of foxM1 gene in laryngeal squamous cell carcinoma]. (23285957)
2012
12
Cigarette smoking and alcohol ingestion as risk factors for laryngeal squamous cell carcinoma at kenyatta national hospital, kenya. (24179405)
2012
13
Expression of VEGF-C/VEGFR-3 in human laryngeal squamous cell carcinomas and its significance for lymphatic metastasis. (22502683)
2012
14
The cadherin-catenin complex in laryngeal squamous cell carcinoma. (22197995)
2012
15
The expression and relationship of CXCR4 and microvessel density in laryngeal squamous cell carcinoma]. (21553525)
2011
16
The involvement of CHD5 hypermethylation in laryngeal squamous cell carcinoma. (21636313)
2011
17
Aurora B kinase expression in laryngeal squamous cell carcinoma and its prognostic implications. (21299608)
2011
18
Podoplanin expression in the development and progression of laryngeal squamous cell carcinomas. (20196862)
2010
19
Study of mRNA expression level and hypermethylation of CHFR promoter in the laryngeal squamous cell carcinoma tissue]. (20942233)
2010
20
Silencing STAT3 with short hairpin RNA enhances radiosensitivity of human laryngeal squamous cell carcinoma xenografts in vivo. (22993624)
2010
21
The expression of hepatocyte growth factor and heparanase in laryngeal squamous cell carcinoma and its clinical significance]. (19452723)
2009
22
Expression and pathobiological significance of Col I, Col IV and Fn in laryngeal squamous cell carcinomas]. (20359090)
2009
23
Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. (19513509)
2009
24
Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. (18604514)
2008
25
Expression of Livin in laryngeal squamous cell carcinoma and relationship with bFGF]. (18476630)
2008
26
The mutation and expression of MUS81 gene in laryngeal squamous cell carcinoma]. (18841572)
2008
27
Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of laryngeal squamous cell carcinoma]. (18826096)
2008
28
Expression of cyclin G1 in laryngeal squamous cell carcinoma and its clinicopathologic significance]. (18788592)
2008
29
The relationship between the activation of ERK and the up-regulation of uPA in laryngeal squamous cell carcinoma]. (17634019)
2007
30
Combined p14ARF and antisense EGFR potentiate the efficacy of adenovirus-mediated gene therapy in laryngeal squamous cell carcinoma (LSCC). (17328665)
2007
31
The expressions and significance of CK2 in normal laryngeal mucosa, laryngeal precancerosis and laryngeal squamous cell carcinoma]. (18062282)
2007
32
Clinical significance and expression of FLIP and PTEN protein in laryngeal squamous cell carcinoma]. (17441421)
2007
33
Fas expression is associated with a better prognosis in laryngeal squamous cell carcinoma. (18225575)
2007
34
The expression of tumor necrosis factor related apoptosis induce ligand in human laryngeal squamous cell carcinoma]. (17357513)
2006
35
Expression of telomerase reverse transcriptase and its relationship with expression of c-myc in laryngeal squamous cell carcinomas]. (17219990)
2006
36
Multivariate survival analysis in patient with laryngeal squamous cell carcinomas]. (17017186)
2006
37
Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness. (16299231)
2005
38
Prognostic significance of Jab1 expression in laryngeal squamous cell carcinomas. (15671554)
2005
39
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. (15746850)
2005
40
Laryngeal squamous cell carcinoma with ectopic production of granulocyte colony-stimulating factor and parathyroid hormone-related protein. (15990969)
2005
41
Expression of VEGF-C and VEGFR-3 in human laryngeal squamous cell carcinomas and cervical metastatic lymph node tissues]. (15715411)
2004
42
Expression and significance of PTEN and caspase-3 in laryngeal squamous cell carcinoma]. (15831044)
2004
43
Gene expression of matrix metalloproteinase 14 in laryngeal squamous cell carcinoma]. (15563089)
2004
44
Correlation of FHIT expression to cell proliferation and metastasis of laryngeal squamous cell carcinoma]. (15522186)
2004
45
p63 in laryngeal squamous cell carcinoma: evidence for a role of TA-p63 down-regulation in tumorigenesis and lack of prognostic implications of p63 immunoreactivity. (12379767)
2002
46
Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas. (11911285)
2001
47
The study of p16 gene mutation and methylation in laryngeal squamous cell carcinoma]. (12768709)
2000
48
Immunohistochemical study of Cath-D and CD44 in laryngeal squamous cell carcinomas]. (11189153)
1998
49
Microvessel count is predictive of patients' survival in laryngeal squamous-cell carcinoma. (8900379)
1996
50
Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. (8883413)
1996

Variations for Laryngeal Squamous Cell Carcinoma

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Cosmic variations for Laryngeal Squamous Cell Carcinoma:

7
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
110808TP53upper aerodigestive tract,larynx,carcinoma,squamous cell carcinoma1

Expression for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Search GEO for disease gene expression data for Laryngeal Squamous Cell Carcinoma.

Pathways for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Pathways related to Laryngeal Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6CCND1, CCNA2
29.4CDKN2B, CCND1, PTEN
3
Show member pathways
PLK2 and PLK4 events36
Polo-like kinase signaling events in the cell cycle36
9.4CDKN2B, CCND1, PTEN
4
Show member pathways
Signal transduction PTEN pathway58
9.4PTEN, CCND1, BIRC5
59.4AURKA, PTEN, CCND1
69.3GSTT1, GSTM1
79.3GSTT1, GSTM1
8
Show member pathways
DNA damage response (only ATM dependent)36
Wnt Signaling Pathway and Pluripotency36
9.3CDKN2A, CCND1, PTEN
9
Show member pathways
DNA damage response36
9.3PTEN, CCND1, CDKN2A
109.3CDKN2A, CCND1, PTEN
11
Show member pathways
glutathione-mediated detoxification I36
glutathione redox reactions I36
glutathione redox reactions II36
4-hydroxy-2-nonenal detoxification36
Glutathione metabolism58
Glutathione metabolism36
9.1GSTT1, GSTM1, GSTM3
12
Show member pathways
Signaling Pathways in Glioblastoma36
9.1CDKN2B, CDKN2A, CCND1, PTEN
13
Show member pathways
Cell cycle36
9.0CCNA2, CCND1, CDKN2A, CDKN2B
14
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation58
9.0CCNA2, CCND1, CDKN2A, CDKN2B
15
Show member pathways
9.0CCNA2, CCND1, CDKN2A, CDKN2B
169.0CCNA2, CCND1, CDKN2A, CDKN2B
17
Show member pathways
9.0CDKN2B, CDKN2A, CCND1, CCNA2
188.9EIF4E, NME1, BIRC5, TERT
198.9TERT, CCND1, CDKN2A, CDKN2B
20
Show member pathways
IL-9 Signaling Pathway36
Development Thrombopoietin regulated cell processes58
IL-7 Signaling Pathway36
Immune response IL 9 signaling pathway58
8.9PTEN, CCNA2, CCND1, BIRC5
21
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.9BIRC5, CCND1, CCNA2, PTEN
22
Show member pathways
8.8GSTT1, GSTM1, GSTM3, NAT2
23
Show member pathways
8.8NAT2, GSTM3, GSTM1, GSTT1
248.8PTEN, CCND1, BIRC5, CDKN2A, CDKN2B
25
Show member pathways
8.8CCNA2, CCND1, BIRC5, CDKN2A, CDKN2B
268.5PTEN, CCNA2, CCND1, NME1, CDKN2B
27
Show member pathways
8.5AURKA, MKI67, CCNA2, CCND1, CDKN2A
28
Show member pathways
8.0PTEN, NAT2, GSTM3, GSTM1, GSTT1, NME1
29
Show member pathways
7.9CDKN2B, CDKN2A, BIRC5, CCND1, CCNA2, AURKA

Compounds for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Compounds related to Laryngeal Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 210)
idCompoundScoreTop Affiliating Genes
1drugs for treatment of tuberculosis499.4GSTT1, NAT2, GSTM1
2p00001439.2CCND1, CDKN2A, BIRC5, MKI67
3crcs439.0CDKN2A, NME1, BIRC5, CCND1, PTEN
4isoniazid43 49 1211.0NAT2, GSTM1, CDKN2A, GSTT1
5aflatoxin b143 2410.0NAT2, GSTM1, GSTT1, CDKN2A
6gsts438.8NAT2, GSTT1, GSTM1, GSTM3
7adriamycin438.7TERT, CTSD, CDKN2A, BIRC5, CCND1
8chi 2438.7NME1, MKI67, GSTT1, GSTM1
9acetone438.7MKI67, CCND1, GSTM1, GSTT1
10mg 13243 599.6CCNA2, CDKN2A, EIF4E, BIRC5, PTEN, CCND1
11p003438.5CTSD, CDKN2B, GSTT1, GSTM1, MKI67
12agar438.5CCND1, PTEN, EIF4E, CDKN2A, CTSD, NME1
13depsipeptide438.3TERT, CCNA2, CDKN2A, CCND1
14butyrate438.3CDKN2A, CCNA2, CCND1, TERT, CTSD, BIRC5
15tamoxifen43 49 28 1211.3MKI67, PTEN, CCNA2, BIRC5, CCND1, CTSD
16tgf beta1438.3MKI67, PTEN, CDKN2B, CCND1, CCNA2
17p002438.2GSTM1, CTSD, NME1, BIRC5, MKI67, GSTT1
18folate438.2MKI67, NAT2, GSTM1, CCND1, GSTT1, CDKN2A
19pd 98,059438.1PTEN, CDKN2B, CCND1, TERT, BIRC5, EIF4E
20rapamycin438.1CCNA2, PTEN, TERT, EIF4E, BIRC5, CCND1
21estradiol43 24 1210.1BIRC5, CCND1, CCNA2, PTEN, MKI67, CTSD
22ly294002438.1EIF4E, PTEN, TERT, BIRC5, CCND1, CCNA2
23genistein43 28 59 2 24 1212.9TERT, PTEN, CCNA2, BIRC5, CDKN2A, CTSD
24cyclophosphamide43 49 129.9GSTT1, NAT2, MKI67, CTSD, PTEN, GSTM1
25arsenite43 248.9CDKN2B, EIF4E, PTEN, TERT, BIRC5, CCND1
26cycloheximide437.8EIF4E, MKI67, CTSD, PTEN, BIRC5, CCND1
27thymidine43 248.8NME1, BIRC5, CCND1, CTSD, CCNA2, TERT
28etoposide43 49 59 1210.7CCNA2, NME1, TERT, CTSD, EIF4E, GSTT1
29aspartate437.7CTSD, PTEN, CCNA2, GSTM1, NME1, CDKN2A
30vincristine43 49 129.6BIRC5, CDKN2A, CCND1, PTEN, MKI67, GSTM1
31methotrexate49 43 129.6CDKN2B, MKI67, CCND1, CCNA2, CDKN2A, BIRC5
32thymidylate437.4CDKN2A, CCNA2, CCND1, BIRC5, GSTM1, MKI67
33paclitaxel43 49 129.3MKI67, AURKA, BIRC5, CTSD, CDKN2A, TERT
34h2o2437.3CCNA2, GSTM1, CTSD, PTEN, TERT, EIF4E
35progesterone43 28 59 24 1211.2NME1, CCNA2, CTSD, MKI67, CDKN2A, BIRC5
36cysteine437.1NME1, GSTM1, NAT2, CTSD, PTEN, TERT
37steroid437.1CDKN2A, CCNA2, MKI67, EIF4E, NME1, GSTT1
38paraffin437.1CDKN2A, CTSD, NME1, BIRC5, CCNA2, PTEN
39oligonucleotide437.1NAT2, CCND1, PTEN, CCNA2, BIRC5, GSTT1
40threonine437.0PTEN, MKI67, AURKA, CDKN2B, CDKN2A, EIF4E
41nitric oxide43 24 128.9EIF4E, NME1, TERT, PTEN, NAT2, CCNA2
42vegf436.8CTSD, BIRC5, PTEN, CCNA2, CCND1, MKI67
435fluorouracil436.7TERT, MKI67, PTEN, CCNA2, BIRC5, GSTM1
44testosterone43 59 24 129.7CCND1, CCNA2, TERT, PTEN, MKI67, BIRC5
45retinoic acid43 247.6NME1, BIRC5, MKI67, CCNA2, CCND1, PTEN
46doxorubicin43 49 128.4CTSD, CDKN2A, TERT, MKI67, PTEN, CCNA2
47serine436.3BIRC5, CCND1, CCNA2, NME1, EIF4E, CDKN2A
48oxygen43 247.3PTEN, CCNA2, MKI67, GSTM1, GSTT1, EIF4E
49cisplatin43 49 59 128.2CCND1, PTEN, MKI67, TERT, CDKN2A, CTSD
50estrogen434.9CCND1, PTEN, CTSD, CDKN2B, TERT, AURKA

GO Terms for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Cellular components related to Laryngeal Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleolusGO:00057307.9CDKN2A, CCND1, PTEN, MKI67, TERT, CDKN2B
2nucleusGO:00056346.8PTEN, CCNA2, CCND1, BIRC5, NME1, CDKN2A
3cytosolGO:00058296.3AURKA, CDKN2B, CDKN2A, EIF4E, NME1, GSTT1
4cytoplasmGO:00057375.7GSTM3, BIRC5, CCNA2, PTEN, MKI67, TERT

Biological processes related to Laryngeal Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of mitotic cell cycleGO:004593110.0EIF4E, BIRC5
2regulation of G2/M transition of mitotic cell cycleGO:00103899.8CCNA2, CDKN2A
3regulation of protein stabilityGO:00316479.7CDKN2A, PTEN, AURKA
4nitrobenzene metabolic processGO:00189169.7GSTM1, GSTM3
5cellular detoxification of nitrogen compoundGO:00704589.7GSTM1, GSTM3
6negative regulation of G1/S transition of mitotic cell cycleGO:020001349.7CDKN2B, PTEN
7response to organic cyclic compoundGO:00140709.7CDKN2B, GSTT1, MKI67
8xenobiotic catabolic processGO:00421789.6GSTM1, GSTM3
9replicative senescenceGO:00903999.6TERT, CDKN2A
10negative regulation of phosphorylationGO:00423269.6CDKN2B, CDKN2A
11G2/M transition of mitotic cell cycleGO:00000869.5AURKA, CCNA2, BIRC5, CDKN2B
12G1/S transition of mitotic cell cycleGO:00000829.5CCND1, EIF4E, CDKN2A
13regulation of cyclin-dependent protein serine/threonine kinase activityGO:00000799.5CDKN2B, CCNA2, PTEN
14glutathione derivative biosynthetic processGO:019016879.4GSTM3, GSTM1, GSTT1
15glutathione metabolic processGO:00067499.4GSTM3, GSTM1, GSTT1
16organ regenerationGO:00311009.3MKI67, CCNA2, CCND1
17xenobiotic metabolic processGO:00068059.1GSTT1, GSTM1, GSTM3, NAT2
18negative regulation of cell proliferationGO:00082859.1CDKN2B, CDKN2A, NME1, PTEN
19mitotic cell cycleGO:00002788.8CDKN2B, CDKN2A, BIRC5, CCND1, CCNA2, AURKA
20small molecule metabolic processGO:00442818.1NME1, GSTT1, GSTM1, GSTM3, NAT2, PTEN

Molecular functions related to Laryngeal Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:00048619.9CDKN2B, CDKN2A
2glutathione bindingGO:00432959.1GSTM1, GSTM3
3glutathione transferase activityGO:00043649.0GSTM3, GSTM1, GSTT1
4enzyme bindingGO:00198998.4PTEN, CCND1, BIRC5, GSTM3, GSTM1
5protein kinase bindingGO:00199018.0CDKN2B, CDKN2A, NME1, CCND1, CCNA2, PTEN
6protein bindingGO:00055155.9TERT, AURKA, MKI67, PTEN, CCNA2, CCND1

Products for genes affiliated with Laryngeal Squamous Cell Carcinoma

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Sources for Laryngeal Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet