MCID: LRY019
MIFTS: 54

Laryngitis malady

Categories: Respiratory diseases, Infectious diseases

Aliases & Classifications for Laryngitis

Aliases & Descriptions for Laryngitis:

Name: Laryngitis 12 42 14 69
Acute Laryngitis 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3437
MeSH 42 D007827
NCIt 47 C26811
SNOMED-CT 64 45913009
UMLS 69 C0023067

Summaries for Laryngitis

Disease Ontology : 12 A laryngeal disease involving an inflammation of the larynx leading to hoarse voice or a complete loss of voice due to irritation of the vocal cords caused by viral, bacterial or fungal infection, inflammation due to overuse of the vocal cords and excessive coughing, smoking, or alcohol consumption.

MalaCards based summary : Laryngitis, also known as acute laryngitis, is related to larynx leiomyoma and tuberculosis, and has symptoms including throat irritation An important gene associated with Laryngitis is HRH2 (Histamine Receptor H2), and among its related pathways/superpathways are TGF-Beta Pathway and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The drugs Dexamethasone and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include lymph node, thyroid and endothelial, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 71 Laryngitis is inflammation of the larynx (voice box). Symptoms often include a hoarse voice and may... more...

Related Diseases for Laryngitis

Diseases in the Laryngitis family:

Chronic Laryngitis Viral Laryngitis
Acute Laryngitis

Diseases related to Laryngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 621)
id Related Disease Score Top Affiliating Genes
1 larynx leiomyoma 30.6 IL1B IL6
2 tuberculosis 30.4 IL1B IL6 TNF
3 pleomorphic rhabdomyosarcoma 29.7 ATP4A HRH2
4 neuropathy 29.3 IL1B IL6 TNF
5 burns 29.2 IL6 TGFB1 TNF
6 colon adenocarcinoma 29.1 IL1B IL6 TNF
7 nasopharyngitis 29.0 IL1A IL1B IL6 TNF
8 cataract 29.0 IL1B TNF
9 histiocytosis 28.9 IL1A IL1B IL6 TNF
10 measles 28.8 IL1B IL6 TNF
11 laryngeal papillomatosis 12.2
12 laryngeal cleft 12.2
13 chronic laryngitis 12.2
14 acute laryngitis 12.2
15 viral laryngitis 12.0
16 laryngeal web, familial 12.0
17 congenital laryngeal palsy 12.0
18 laryngeal tuberculosis 11.9
19 laryngeal abductor paralysis 11.9
20 laryngeal disease 11.9
21 laryngeal cartilage cancer 11.9
22 laryngeal small cell carcinoma 11.8
23 supraglottic laryngeal cancer 11.8
24 laryngeal adenoid cystic carcinoma 11.8
25 laryngeal mucoepidermoid carcinoma 11.8
26 laryngeal adductor paralysis 11.8
27 congenital laryngeal cyst 11.8
28 laryngeal neuroendocrine tumor 11.7
29 larynx cancer 11.6
30 vater-like defects with pulmonary hypertension, laryngeal webs, and growth deficiency 11.6
31 laryngeal abductor paralysis mental retardation 11.6
32 laryngeal cancer, childhood 11.6
33 primary laryngeal lymphangioma 11.6
34 spasmodic dysphonia 11.6
35 laryngomalacia 11.5
36 recurrent respiratory papillomatosis 11.5
37 dystonia 24 11.3
38 croup 11.3
39 urbach-wiethe disease 11.1
40 thyroiditis 11.1
41 fraser syndrome 11.0
42 van den ende-gupta syndrome 11.0
43 mucocutaneous leishmaniasis 11.0
44 dystonia 25 10.8
45 dystonia 4, torsion, autosomal dominant 10.8
46 shprintzen omphalocele syndrome 10.8
47 spasmodic dystonia 10.8
48 squamous cell carcinoma 10.7
49 dystonia 16 10.7
50 farber lipogranulomatosis 10.7

Comorbidity relations with Laryngitis via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Deficiency Anemia Esophagitis
Heart Disease Hypertension, Essential
Ischemic Heart Disease Pharyngitis

Graphical network of the top 20 diseases related to Laryngitis:



Diseases related to Laryngitis

Symptoms & Phenotypes for Laryngitis

UMLS symptoms related to Laryngitis:


throat irritation

MGI Mouse Phenotypes related to Laryngitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.8 FGF2 IL1A IL1B IL6 TGFB1 TNF
2 hematopoietic system MP:0005397 9.7 ATP4A FGF2 IL1A IL1B IL6 TGFB1
3 digestive/alimentary MP:0005381 9.65 ATP4A HRH2 IL6 TGFB1 TNF
4 homeostasis/metabolism MP:0005376 9.56 ATP4A FGF2 HRH2 IL1A IL1B IL6
5 neoplasm MP:0002006 9.1 FGF2 IL1A IL1B IL6 TGFB1 TNF

Drugs & Therapeutics for Laryngitis

Drugs for Laryngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 82)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
2
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
5
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 5281106 54677470
6
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 4594 9579578
7
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
8
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
9
Salmeterol xinafoate Phase 4 94749-08-3 56801
10 Dexamethasone acetate Phase 4 1177-87-3
11
Fluticasone Phase 4,Phase 3 90566-53-3, 80474-14-2 62924 22833648
12
Proton pump inhibitors Phase 4,Phase 2,Phase 3
13 glucocorticoids Phase 4,Phase 3
14
protease inhibitors Phase 4
15 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4
16 Mydriatics Phase 4
17 Adrenergic Agents Phase 4,Phase 2,Phase 3
18 Adrenergic Agonists Phase 4
19 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
20 Adrenergic alpha-Agonists Phase 4
21 Adrenergic beta-2 Receptor Agonists Phase 4
22 Adrenergic beta-Agonists Phase 4
23 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
24 HIV Protease Inhibitors Phase 4
25 Dermatologic Agents Phase 4,Phase 3
26 Hormone Antagonists Phase 4,Phase 3
27 Dexamethasone 21-phosphate Phase 4
28 Hormones Phase 4,Phase 3
29 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
30 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
31 Vasoconstrictor Agents Phase 4
32 Epinephryl borate Phase 4
33 Anti-Allergic Agents Phase 4,Phase 3
34 Anti-Asthmatic Agents Phase 4,Phase 3
35 Antiemetics Phase 4
36 Anti-Inflammatory Agents Phase 4,Phase 3
37 Racepinephrine Phase 4
38 Respiratory System Agents Phase 4,Phase 3
39 BB 1101 Phase 4
40 Autonomic Agents Phase 4,Phase 3
41 Antineoplastic Agents, Hormonal Phase 4,Phase 3
42 Bronchodilator Agents Phase 4,Phase 3
43 Analgesics Phase 4,Phase 2,Phase 3
44 Cyclooxygenase Inhibitors Phase 4
45 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
46 Antacids Phase 4,Phase 2,Phase 3
47 Anti-Inflammatory Agents, Non-Steroidal Phase 4
48 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3
49 Antirheumatic Agents Phase 4
50
Dexlansoprazole Phase 4 138530-94-6, 103577-45-3 9578005

Interventional clinical trials:

(show all 24)
id Name Status NCT ID Phase
1 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4
2 The Effect and Safety of Low Dose Nebulized Epinephrine in Croup Unknown status NCT01664507 Phase 4
3 Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux Completed NCT00628667 Phase 4
4 Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4
5 Quality of Life Validation in Laryngitis Completed NCT00641264 Phase 4
6 Community Care for Croup (RCT) Completed NCT01042145 Phase 4
7 Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux Terminated NCT00369265 Phase 4
8 Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed NCT00204698 Phase 2, Phase 3
9 CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study Completed NCT01948856 Phase 3
10 Management of Recurrent Croup Completed NCT01748162 Phase 3
11 Treatment of Chronic Laryngitis With Amitriptyline Recruiting NCT02552225 Phase 2, Phase 3
12 Trial of the Treatment of Chronic Laryngitis With Amitryptiline Terminated NCT02434523 Phase 2, Phase 3
13 Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup Terminated NCT00938353 Phase 3
14 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants Completed NCT00611390 Phase 1, Phase 2
15 Comparing Different Ways of Delivering Humidity to Children With Croup Completed NCT00230841 Phase 2
16 Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR Unknown status NCT01755221
17 Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children Unknown status NCT02056379
18 Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis Completed NCT01806220
19 Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients Completed NCT00517114
20 Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis Completed NCT01389401
21 Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis Completed NCT02160912
22 Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists Completed NCT02048449
23 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275
24 A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup Terminated NCT00147849

Search NIH Clinical Center for Laryngitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: laryngitis

Genetic Tests for Laryngitis

Anatomical Context for Laryngitis

MalaCards organs/tissues related to Laryngitis:

39
Lymph Node, Thyroid, Endothelial, Lung, T Cells, Skin, Testes

Publications for Laryngitis

Articles related to Laryngitis:

(show top 50) (show all 3412)
id Title Authors Year
1
Conservative surgery for laryngeal chondrosarcoma: a review of the most recently proposed approaches. ( 28059901 )
2017
2
Laryngeal lipoma: a rare cause of dysphonia. ( 28450988 )
2017
3
Laryngeal alveolar soft part sarcoma: A case report of a rare malignancy in an atypical location. ( 28131550 )
2017
4
Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma. ( 28345455 )
2017
5
Minimally invasive endoscopic treatment for pediatric combined high grade stenosis as a laryngeal manifestation of epidermolysis bullosa. ( 28012513 )
2017
6
The expression and function of epithelial membrane protein 1 in laryngeal carcinoma. ( 27909719 )
2017
7
Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from aspiration pneumonia. ( 28024728 )
2017
8
Functional significance of the long non-coding RNA RP11-169D4.1 as a metastasis suppressor in laryngeal squamous cell carcinoma by regulating CDH1. ( 28534968 )
2017
9
Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90I^. ( 27959448 )
2017
10
CCL20/CCR6 promotes cell proliferation and metastasis in laryngeal cancer by activating p38 pathway. ( 27916417 )
2017
11
Ascorbic Acid Induces Necrosis in Human Laryngeal Squamous Cell Carcinoma via ROS, PKC, and Calcium Signaling. ( 27211910 )
2017
12
Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population. ( 28362993 )
2017
13
SHISA3 Promoter Methylation Is a Potential Diagnostic and Prognostic Biomarker for Laryngeal Squamous Cell Carcinoma. ( 28299336 )
2017
14
The pre-treatment neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and red cell distribution width predict prognosis in patients with laryngeal carcinoma. ( 27520567 )
2016
15
Evaluation of the CD44 isoform v-6 (sCD44var, v6) in the saliva of patients with laryngeal carcinoma and its prognostic role. ( 26756618 )
2016
16
High BAX/BCL2 mRNA ratio predicts favorable prognosis in laryngeal squamous cell carcinoma, particularly in patients with negative lymph nodes at the time of diagnosis. ( 27129795 )
2016
17
Identification of key genes for laryngeal squamous cell carcinoma using weighted co-expression network analysis. ( 27123111 )
2016
18
miR-375 exhibits a more effective tumor-suppressor function in laryngeal squamous carcinoma cells by regulating KLF4 expression compared with simple co-transfection of miR-375 and miR-206. ( 27279635 )
2016
19
Detection of O6-methylguanine-DNA methyltransferase gene promoter region methylation pattern using pyrosequencing and the effect of methylation pattern on survival, recurrence, and chemotherapy sensitivity in patients with laryngeal cancer. ( 27067808 )
2016
20
A rare laryngeal tumor in a patient with thyroid papillary cancer: granular cell tumor. ( 27068886 )
2016
21
Association between UGT1A1 Polymorphism and Risk of Laryngeal Squamous Cell Carcinoma. ( 26751466 )
2016
22
CYP1A1 rs1048943 and rs4646903 polymorphisms associated with laryngeal cancer susceptibility among Asian populations: a meta-analysis. ( 26578427 )
2016
23
Up-Regulation of Angiotensin-Converting Enzyme (ACE) Enhances Cell Proliferation and Predicts Poor Prognosis in Laryngeal Cancer. ( 27801393 )
2016
24
Specific patterns of laryngeal electromyography during wakefulness are associated to sleep disordered breathing and nocturnal stridor in multiple system atrophy. ( 27510647 )
2016
25
Intermittent neural monitoring of the recurrent laryngeal nerve in surgery for recurrent goiter. ( 27867862 )
2016
26
Droplet digital PCR and qRT-PCR to detect circulating miR-21 in laryngeal squamous cell carcinoma and pre-malignant laryngeal lesions. ( 27067271 )
2016
27
Predictive factors and treatment outcome of laryngeal carcinoma recurrence. ( 27902867 )
2016
28
Three-dimensional printing as an aid to airway evaluation after tracheotomy in a patient with laryngeal carcinoma. ( 26781803 )
2016
29
Connexin 43 (Cx43) Expression in Laryngeal Squamous Cell Carcinomas: Preliminary Data on Its Possible Prognostic Role. ( 26748803 )
2016
30
Implementation of a rapid learning platform: Predicting 2-year survival in laryngeal carcinoma patients in a clinical setting. ( 27095578 )
2016
31
Health-related Quality of Life as Studied by EORTC QLQ and Voice Handicap Index Among Various Patients With Laryngeal Disease. ( 27520510 )
2016
32
Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma. ( 27400252 )
2016
33
Changing the paradigm: the potential for targeted therapy in laryngeal squamous cell carcinoma. ( 27144065 )
2016
34
SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males. ( 26796520 )
2016
35
The clinical diagnostic value of target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition. ( 27037849 )
2016
36
Analysis of Postsurgical Health-Related Quality of Life and Quality of Voice of Patients With Laryngeal Carcinoma. ( 26735538 )
2016
37
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. ( 26701176 )
2016
38
The prognostic role of Eg5 expression in laryngeal squamous cell carcinoma. ( 27020495 )
2016
39
Unilateral Vocal Cord Paralysis following Insertion of a Supreme Laryngeal Mask in a Patient with SjAPgren's Syndrome. ( 28018681 )
2016
40
Laryngeal metastasis from bile duct adenocarcinoma. ( 26614301 )
2016
41
Prospective Controlled Study of Gastroesophageal Reflux in Dogs with Naturally Occurring Laryngeal Paralysis. ( 27611104 )
2016
42
Modified Best-Practice Algorithm to Reduce the Number of Postoperative Videofluoroscopic Swallow Studies in Patients With Type 1 Laryngeal Cleft Repair. ( 27356238 )
2016
43
Laryngeal inflammatory myofibroblastic tumor (IMT): a case report and review of the literature. ( 27339455 )
2016
44
Lateral Cricoarytenoid Release: Development of a Novel Surgical Treatment Option for Adductor Spasmodic Dysphonia in a Canine Laryngeal Model. ( 27257292 )
2016
45
Laryngeal myofascial pain syndrome as a new diagnostic entity of dysphonia. ( 27262220 )
2016
46
Expression of Th1- Th2- and Th17-associated cytokines in laryngeal carcinoma. ( 27588143 )
2016
47
Tumiform Laryngeal Histoplasmosis. ( 27831533 )
2016
48
Continuous intraoperative monitoring of vagus and recurrent laryngeal nerve function in patients with advanced atrioventricular block. ( 27138019 )
2016
49
Activation of the FAK/PI3K pathway is crucial for AURKA-induced epithelial-mesenchymal transition in laryngeal cancer. ( 27373675 )
2016
50
Laryngeal Verrucous Carcinoma: A Systematic Review. ( 27484231 )
2016

Variations for Laryngitis

Expression for Laryngitis

Search GEO for disease gene expression data for Laryngitis.

Pathways for Laryngitis

Pathways related to Laryngitis according to GeneCards Suite gene sharing:

(show top 50) (show all 72)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.42 FGF2 IL1A IL1B IL6 TGFB1 TNF
2
Show member pathways
13.37 ATP4A IL1A IL1B IL6 TGFB1 TNF
3
Show member pathways
13.31 FGF2 IL1A IL1B IL6 TGFB1 TNF
4
Show member pathways
13.27 FGF2 IL1A IL1B IL6 TGFB1 TNF
5
Show member pathways
13.21 FGF2 IL1A IL1B IL6 TGFB1 TNF
6
Show member pathways
12.88 IL1A IL1B IL6 TNF
7
Show member pathways
12.81 IL1B IL6 TGFB1 TNF
8
Show member pathways
12.79 IL1A IL1B IL6 TGFB1 TNF
9
Show member pathways
12.71 IL1A IL1B IL6 TNF
10 12.65 FGF2 IL1A IL1B TGFB1 TNF
11
Show member pathways
12.54 IL1A IL1B IL6 TGFB1 TNF
12
Show member pathways
12.53 FGF2 IL1B IL6 TNF
13
Show member pathways
12.53 FGF2 IL1A IL1B IL6 TGFB1 TNF
14
Show member pathways
12.37 IL1A IL1B IL6 TGFB1 TNF
15 12.33 IL6 TGFB1 TNF
16
Show member pathways
12.25 IL1B IL6 TNF
17
Show member pathways
12.25 IL1B IL6 TNF
18
Show member pathways
12.25 IL1A IL1B IL6 TNF
19
Show member pathways
12.24 IL1A IL1B TGFB1 TNF
20 12.22 FGF2 TGFB1 TNF
21
Show member pathways
12.19 IL1A IL6 TNF
22 12.16 IL1A IL1B IL6 TGFB1 TNF
23 12.15 IL1A IL1B IL6 TNF
24
Show member pathways
12.14 IL6 TGFB1 TNF
25
Show member pathways
12.13 IL1A IL1B IL6 TNF
26
Show member pathways
12.12 IL1B IL6 TNF
27 12.12 IL6 TGFB1 TNF
28
Show member pathways
12.1 FGF2 TGFB1 TNF
29 12.04 IL1A IL1B TNF
30 12.02 FGF2 IL6 TGFB1
31 12.02 IL1A IL1B TGFB1 TNF
32 12.01 IL6 TGFB1 TNF
33
Show member pathways
11.93 IL1B IL6 TGFB1 TNF
34 11.92 IL1B IL6 TNF
35 11.92 IL1A IL1B IL6 TGFB1
36
Show member pathways
11.89 IL1B IL6 TGFB1
37 11.87 IL1A IL1B IL6 TNF
38 11.86 FGF2 IL6 TGFB1
39 11.86 IL1B IL6 TGFB1 TNF
40 11.85 IL1A IL1B IL6 TGFB1 TNF
41 11.81 IL1A IL1B IL6
42 11.73 IL1B IL6 TGFB1 TNF
43 11.72 IL1A IL1B IL6 TNF
44 11.72 IL1A IL1B IL6 TGFB1 TNF
45 11.71 IL6 TGFB1 TNF
46
Show member pathways
11.62 IL1A IL1B IL6 TNF
47 11.61 IL1A IL1B IL6 TGFB1 TNF
48 11.6 IL1B IL6 TNF
49 11.53 IL1B TGFB1 TNF
50 11.53 FGF2 IL6 TGFB1

GO Terms for Laryngitis

Cellular components related to Laryngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 FGF2 IL1A IL1B IL6 TGFB1 TNF
2 extracellular space GO:0005615 9.17 ATP4A FGF2 IL1A IL1B IL6 TGFB1

Biological processes related to Laryngitis according to GeneCards Suite gene sharing:

(show top 50) (show all 66)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.97 IL1A IL1B IL6 TGFB1
2 positive regulation of transcription, DNA-templated GO:0045893 9.97 FGF2 IL1B IL6 TGFB1 TNF
3 positive regulation of transcription from RNA polymerase II promoter GO:0045944 9.93 FGF2 IL1A IL1B IL6 TGFB1 TNF
4 regulation of cell proliferation GO:0042127 9.91 IL6 TGFB1 TNF
5 MAPK cascade GO:0000165 9.91 FGF2 IL1B TGFB1 TNF
6 leukocyte migration GO:0050900 9.9 IL1B TGFB1 TNF
7 immune response GO:0006955 9.89 HRH2 IL1A IL1B IL6 TNF
8 positive regulation of protein phosphorylation GO:0001934 9.88 IL1B TGFB1 TNF
9 cytokine-mediated signaling pathway GO:0019221 9.87 IL1A IL1B IL6
10 positive regulation of angiogenesis GO:0045766 9.85 FGF2 IL1A IL1B
11 activation of MAPK activity GO:0000187 9.84 FGF2 IL1B TNF
12 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.83 IL1B IL6 TNF
13 wound healing GO:0042060 9.83 FGF2 IL6 TGFB1
14 positive regulation of protein kinase B signaling GO:0051897 9.81 IL6 TGFB1 TNF
15 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.81 FGF2 IL6 TGFB1 TNF
16 cellular response to organic cyclic compound GO:0071407 9.8 IL1B TGFB1 TNF
17 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.79 IL6 TGFB1 TNF
18 positive regulation of MAP kinase activity GO:0043406 9.77 FGF2 TGFB1 TNF
19 positive regulation of protein secretion GO:0050714 9.74 IL1A TGFB1
20 cellular response to dexamethasone stimulus GO:0071549 9.74 IL6 TGFB1
21 digestive tract development GO:0048565 9.73 HRH2 TGFB1
22 regulation of angiogenesis GO:0045765 9.73 FGF2 IL6
23 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.73 FGF2 TGFB1
24 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.73 IL1A IL1B
25 positive regulation of phagocytosis GO:0050766 9.73 IL1B TNF
26 positive regulation of cytokine secretion GO:0050715 9.72 IL1A TNF
27 protein import into nucleus, translocation GO:0000060 9.72 TGFB1 TNF
28 negative regulation of mitotic cell cycle GO:0045930 9.72 TGFB1 TNF
29 positive regulation of mitotic nuclear division GO:0045840 9.72 IL1A IL1B
30 positive regulation of interleukin-8 production GO:0032757 9.71 IL1B TNF
31 positive regulation of protein complex assembly GO:0031334 9.71 TGFB1 TNF
32 positive regulation of blood vessel endothelial cell migration GO:0043536 9.71 FGF2 TGFB1
33 positive regulation of NF-kappaB import into nucleus GO:0042346 9.71 IL1B TNF
34 negative regulation of myoblast differentiation GO:0045662 9.71 TGFB1 TNF
35 negative regulation of fat cell differentiation GO:0045599 9.71 IL6 TGFB1 TNF
36 positive regulation of histone acetylation GO:0035066 9.7 IL1B TGFB1
37 negative regulation of lipid catabolic process GO:0050995 9.7 IL1B TNF
38 positive regulation of nitric oxide biosynthetic process GO:0045429 9.7 IL1B IL6 TNF
39 positive regulation of chemokine production GO:0032722 9.69 IL6 TNF
40 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.69 IL1B TNF
41 hyaluronan catabolic process GO:0030214 9.69 FGF2 TGFB1
42 negative regulation of blood vessel endothelial cell migration GO:0043537 9.68 FGF2 TGFB1
43 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.68 IL1B TNF
44 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.68 IL1B TNF
45 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.68 IL1A IL1B
46 positive regulation of chemokine biosynthetic process GO:0045080 9.66 IL1B TNF
47 negative regulation of lipid storage GO:0010888 9.65 IL6 TNF
48 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.65 IL1A IL1B
49 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.65 IL1A IL1B TNF
50 inflammatory response GO:0006954 9.65 IL1A IL1B IL6 TGFB1 TNF

Molecular functions related to Laryngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.33 FGF2 IL6 TGFB1
2 cytokine activity GO:0005125 9.1 FGF2 IL1A IL1B IL6 TGFB1 TNF
3 interleukin-1 receptor binding GO:0005149 8.96 IL1A IL1B

Sources for Laryngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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