MCID: LRY019
MIFTS: 53

Laryngitis

Categories: Respiratory diseases, Infectious diseases

Aliases & Classifications for Laryngitis

MalaCards integrated aliases for Laryngitis:

Name: Laryngitis 12 42 14 69
Acute Laryngitis 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3437
MeSH 42 D007827
NCIt 47 C26811
SNOMED-CT 64 45913009
UMLS 69 C0023067

Summaries for Laryngitis

Disease Ontology : 12 A laryngeal disease involving an inflammation of the larynx leading to hoarse voice or a complete loss of voice due to irritation of the vocal cords caused by viral, bacterial or fungal infection, inflammation due to overuse of the vocal cords and excessive coughing, smoking, or alcohol consumption.

MalaCards based summary : Laryngitis, also known as acute laryngitis, is related to tracheal stenosis and dysphagia, and has symptoms including throat irritation An important gene associated with Laryngitis is HRH2 (Histamine Receptor H2), and among its related pathways/superpathways are TGF-Beta Pathway and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The drugs Epinephrine and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include lymph node, thyroid and endothelial, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 72 Laryngitis is inflammation of the larynx (voice box). Symptoms often include a hoarse voice and may... more...

Related Diseases for Laryngitis

Diseases in the Laryngitis family:

Chronic Laryngitis Viral Laryngitis
Acute Laryngitis

Diseases related to Laryngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 652)
id Related Disease Score Top Affiliating Genes
1 tracheal stenosis 30.7 IL6 TNF
2 dysphagia 30.2 IL6 TNF
3 rhabdomyosarcoma 30.1 ATP4A HRH2
4 lymphoma 29.9 IL1B IL6 TNF
5 cataract 29.6 IL1B TNF
6 epulis 29.6 IL1B TNF
7 colon adenocarcinoma 29.5 IL1B IL6 TNF
8 myeloid sarcoma 29.2 IL1B IL6 TNF
9 noma 29.2 IL1B IL6 TNF
10 charcot-marie-tooth disease 29.1 IL1B IL6 TNF
11 acral lentiginous melanoma 29.1 IL1B IL6 TNF
12 myofascial pain syndrome 29.1 IL1A IL6
13 c1 inhibitor deficiency 28.6 IL6 TNF
14 vacterl association 28.6 IL1B IL6 TGFB1 TNF
15 sinusitis 28.1 IL1A IL1B TGFB1 TNF
16 pleomorphic lipoma 27.9 IL1A IL1B IL6 TNF
17 asbestosis 27.7 IL1A IL1B IL6 TGFB1 TNF
18 rheumatoid arthritis 27.4 IL1A IL1B IL6 TGFB1 TNF
19 asthma 27.2 HRH2 IL1A IL1B IL6 TNF
20 laryngeal cleft 12.2
21 laryngeal papillomatosis 12.2
22 chronic laryngitis 12.2
23 acute laryngitis 12.1
24 laryngeal web, familial 12.0
25 viral laryngitis 12.0
26 congenital laryngeal palsy 12.0
27 laryngeal abductor paralysis 11.9
28 laryngeal tuberculosis 11.9
29 laryngeal cartilage cancer 11.9
30 laryngeal disease 11.9
31 supraglottic laryngeal cancer 11.8
32 laryngeal small cell carcinoma 11.8
33 laryngeal adductor paralysis 11.8
34 congenital laryngeal cyst 11.8
35 laryngeal adenoid cystic carcinoma 11.8
36 laryngeal mucoepidermoid carcinoma 11.8
37 laryngeal neuroendocrine tumor 11.7
38 vater-like defects with pulmonary hypertension, laryngeal webs, and growth deficiency 11.6
39 laryngeal abductor paralysis mental retardation 11.6
40 laryngeal cancer, childhood 11.6
41 primary laryngeal lymphangioma 11.6
42 larynx cancer 11.6
43 spasmodic dysphonia 11.6
44 laryngomalacia 11.5
45 recurrent respiratory papillomatosis 11.5
46 dystonia 24 11.4
47 shprintzen omphalocele syndrome 11.3
48 croup 11.3
49 urbach-wiethe disease 11.1
50 thyroiditis 11.1

Comorbidity relations with Laryngitis via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Deficiency Anemia Esophagitis
Heart Disease Hypertension, Essential
Ischemic Heart Disease Pharyngitis

Graphical network of the top 20 diseases related to Laryngitis:



Diseases related to Laryngitis

Symptoms & Phenotypes for Laryngitis

UMLS symptoms related to Laryngitis:


throat irritation

MGI Mouse Phenotypes related to Laryngitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.8 FGF2 IL1A IL1B IL6 TGFB1 TNF
2 hematopoietic system MP:0005397 9.7 TGFB1 TNF ATP4A FGF2 IL1A IL1B
3 digestive/alimentary MP:0005381 9.65 ATP4A HRH2 IL6 TGFB1 TNF
4 homeostasis/metabolism MP:0005376 9.56 ATP4A FGF2 HRH2 IL1A IL1B IL6
5 neoplasm MP:0002006 9.1 FGF2 IL1A IL1B IL6 TGFB1 TNF

Drugs & Therapeutics for Laryngitis

Drugs for Laryngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 81)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2 Racepinephrine Approved Phase 4
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
5
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 4594 9579578
6
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
7
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 5281106 54677470
8
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
9
Dexlansoprazole Approved Phase 4 138530-94-6, 103577-45-3 9578005
10
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
11 Adrenergic Agents Phase 4,Phase 2,Phase 3
12 Adrenergic Agonists Phase 4
13 Adrenergic beta-2 Receptor Agonists Phase 4
14 Adrenergic beta-Agonists Phase 4
15 Anti-Allergic Agents Phase 4,Phase 3
16 Anti-Asthmatic Agents Phase 4,Phase 3
17 Anti-Inflammatory Agents Phase 4,Phase 3
18 Autonomic Agents Phase 4,Phase 3
19 Bronchodilator Agents Phase 4,Phase 3
20 Dermatologic Agents Phase 4,Phase 3
21
Fluticasone Phase 4,Phase 3 90566-53-3, 80474-14-2 62924 22833648
22 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4
23 glucocorticoids Phase 4,Phase 3
24 Hormone Antagonists Phase 4,Phase 3
25 Hormones Phase 4,Phase 3
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
27 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
28 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
29 Respiratory System Agents Phase 4,Phase 3
30
Salmeterol xinafoate Phase 4 94749-08-3 56801
31 Adrenergic alpha-Agonists Phase 4
32 Epinephryl borate Phase 4
33 Mydriatics Phase 4
34 Vasoconstrictor Agents Phase 4
35 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
36
Proton pump inhibitors Phase 4,Phase 2,Phase 3
37 Antiemetics Phase 4
38 Antineoplastic Agents, Hormonal Phase 4,Phase 3
39 BB 1101 Phase 4
40 Dexamethasone acetate Phase 4 1177-87-3
41 HIV Protease Inhibitors Phase 4
42
protease inhibitors Phase 4
43 Antacids Phase 4,Phase 2,Phase 3
44 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3
45 Analgesics Phase 4,Phase 2,Phase 3
46 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
47 Anti-Inflammatory Agents, Non-Steroidal Phase 4
48 Antirheumatic Agents Phase 4
49 Cyclooxygenase Inhibitors Phase 4
50
Rabeprazole Approved, Investigational Phase 2, Phase 3 117976-89-3 5029

Interventional clinical trials:

(show all 25)

id Name Status NCT ID Phase Drugs
1 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4 fluticasone/salmeterol DISKUS 250/50
2 The Effect and Safety of Low Dose Nebulized Epinephrine in Croup Unknown status NCT01664507 Phase 4 conventional dose epinephrine;low dose epinephrine
3 Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux Completed NCT00628667 Phase 4 Esomeprazole;Placebo
4 Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4 Meloxicam;Diclofenac;Nimesulide
5 Quality of Life Validation in Laryngitis Completed NCT00641264 Phase 4 Omeprazole
6 Community Care for Croup (RCT) Completed NCT01042145 Phase 4 Prednisone;Dexamethasone
7 Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux Terminated NCT00369265 Phase 4 Lansoprazole
8 Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed NCT00204698 Phase 2, Phase 3 Aciphex
9 CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study Completed NCT01948856 Phase 3 J022X ST;Placebo
10 Management of Recurrent Croup Completed NCT01748162 Phase 3 Fluticasone
11 Treatment of Chronic Laryngitis With Amitriptyline Suspended NCT02552225 Phase 2, Phase 3 Amitriptyline
12 Trial of the Treatment of Chronic Laryngitis With Amitryptiline Terminated NCT02434523 Phase 2, Phase 3 Amitriptyline
13 Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup Terminated NCT00938353 Phase 3 beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml;Placebo solution for nebulisation 2 ml
14 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants Completed NCT00611390 Phase 1, Phase 2
15 Comparing Different Ways of Delivering Humidity to Children With Croup Completed NCT00230841 Phase 2
16 Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR Unknown status NCT01755221
17 Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children Unknown status NCT02056379 Budesonide;Dexamethasone
18 Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis Completed NCT01806220
19 Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients Completed NCT00517114 Rabeprazole 20mg twice daily
20 Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis Completed NCT01389401 omeprazole
21 Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis Completed NCT02160912
22 Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists Completed NCT02048449
23 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275 Amoxicillin and clavulanate
24 The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold Not yet recruiting NCT03309995
25 A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup Terminated NCT00147849

Search NIH Clinical Center for Laryngitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: laryngitis

Genetic Tests for Laryngitis

Anatomical Context for Laryngitis

MalaCards organs/tissues related to Laryngitis:

39
Lymph Node, Thyroid, Endothelial, Lung, Skin, T Cells, Testes

Publications for Laryngitis

Articles related to Laryngitis:

(show top 50) (show all 3450)
id Title Authors Year
1
Histoplasmosis presenting as laryngeal ulcer in a post-renal transplant male: An unusual case from India. ( 28736209 )
2017
2
Laryngeal stridor in rheumatoid arthritis. ( 28947548 )
2017
3
Gardasil Vaccination for Recurrent Laryngeal Papillomatosis in Adult Men Second Report: Negative Conversion of HPV in Laryngeal Secretions. ( 28866231 )
2017
4
A Case Series of the Probability Density and Cumulative Distribution of Laryngeal Disease in a Tertiary Care Voice Center. ( 28949246 )
2017
5
Long non-coding RNA CCAT1/miR-218/ZFX axis modulates the progression of laryngeal squamous cell cancer. ( 28631575 )
2017
6
Conservative surgery for laryngeal chondrosarcoma: a review of the most recently proposed approaches. ( 28059901 )
2017
7
The expression and function of epithelial membrane protein 1 in laryngeal carcinoma. ( 27909719 )
2017
8
Role of intraoperative neuromonitoring of the recurrent laryngeal nerves during thyroid reoperations of recurrent goiter. ( 28703113 )
2017
9
Factors Associated With Infectious Laryngitis: A Retrospective Review of 15 Cases. ( 28397557 )
2017
10
Laryngeal distribution of recurrent respiratory papillomatosis in a previously untreated cohort. ( 28714564 )
2017
11
Macrophage type 2 differentiation in a patient with laryngeal squamous cell carcinoma and metastatic prostate adenocarcinoma to the cervical lymph nodes. ( 28716144 )
2017
12
Herpes Simplex Virus Laryngitis Presenting as Airway Obstruction: A Case Report and Literature Review. ( 28397560 )
2017
13
TNF-I+ inhibitor as a cause of refractory suppurative laryngitis and rhinosinusitis. ( 28931201 )
2017
14
A retrospective analysis of seven patients with acquired immunodeficiency syndrome and pharyngeal and/or laryngeal Talaromyces marneffei infection. ( 28130931 )
2017
15
Allergic laryngitis: unraveling the myths. ( 28266945 )
2017
16
Functional significance of the long non-coding RNA RP11-169D4.1 as a metastasis suppressor in laryngeal squamous cell carcinoma by regulating CDH1. ( 28534968 )
2017
17
Genetic polymorphisms and plasma levels of BCL11A contribute to the development of laryngeal squamous cell carcinoma. ( 28225775 )
2017
18
Laryngeal lipoma: a rare cause of dysphonia. ( 28450988 )
2017
19
Laryngeal Rosai-Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy): A Retrospective Study of 5 Cases. ( 28770226 )
2017
20
Lewis-Sumner Syndrome Manifesting as Unilateral Vocal Fold Paresis and Laryngeal Fasciculations. ( 28781097 )
2017
21
Neurologic Evaluation in Children With Laryngeal Cleft. ( 28384788 )
2017
22
Expression of Cell Cycle-related Proteins p16, p27 and Ki-67 Proliferating Marker in Laryngeal Squamous Cell Carcinomas and in Laryngeal Papillomas. ( 28476808 )
2017
23
Laryngeal alveolar soft part sarcoma: A case report of a rare malignancy in an atypical location. ( 28131550 )
2017
24
Ascorbic Acid Induces Necrosis in Human Laryngeal Squamous Cell Carcinoma via ROS, PKC, and Calcium Signaling. ( 27211910 )
2017
25
Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from aspiration pneumonia. ( 28024728 )
2017
26
Aberrant expression of CDK8 regulates the malignant phenotype and associated with poor prognosis in human laryngeal squamous cell carcinoma. ( 28220308 )
2017
27
SHISA3 Promoter Methylation Is a Potential Diagnostic and Prognostic Biomarker for Laryngeal Squamous Cell Carcinoma. ( 28299336 )
2017
28
Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population. ( 28362993 )
2017
29
Recurrent laryngeal nerve injury and hypoparathyroidism rates in reoperative thyroid surgery. ( 28589182 )
2017
30
CCL20/CCR6 promotes cell proliferation and metastasis in laryngeal cancer by activating p38 pathway. ( 27916417 )
2017
31
Bisphenol A triggers proliferation and migration of laryngeal squamous cell carcinoma via GPER mediated upregulation of IL-6. ( 28466560 )
2017
32
Cyclooxygenase-2 Inhibition Enhances Proliferation of NKT Cells Derived from Patients with Laryngeal Cancer. ( 28739688 )
2017
33
Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3I^-involved Wnt/I^-catenin pathway. ( 28122350 )
2017
34
A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma. ( 28949956 )
2017
35
The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone. ( 28475003 )
2017
36
Laryngeal tuberculosis: a forgotten disease. ( 28383648 )
2017
37
Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance. ( 27876461 )
2017
38
Tracheobronchopathia osteochondroplastica following laryngeal tuberculosis. ( 28869241 )
2017
39
Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma. ( 28345455 )
2017
40
Minimally invasive endoscopic treatment for pediatric combined high grade stenosis as a laryngeal manifestation of epidermolysis bullosa. ( 28012513 )
2017
41
A case of adult congenital laryngeal cleft asymptomatic until hypopharynx cancer treatment. ( 28943051 )
2017
42
Recurrent Laryngeal Papillomatosis. ( 28160882 )
2017
43
Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90I^. ( 27959448 )
2017
44
Images in Anesthesiology: Laryngeal Cleft. ( 28098610 )
2017
45
Trans-nasal flexible bronchoscopy in wheezing children: Diagnostic yield, impact on therapy, and prevalence of laryngeal cleft. ( 28910519 )
2017
46
The role of long non-coding RNA HOTAIR in the progression and development of laryngeal squamous cell carcinoma interacting with EZH2. ( 27542077 )
2017
47
Sleep-Related Laryngeal Stridor in Opsoclonus Myoclonus Syndrome. ( 28823798 )
2017
48
Assessment of the feeding Swallowing Impact Survey as a quality of life measure in children with laryngeal cleft before and after repair. ( 28688569 )
2017
49
Laryngeal Verrucous Carcinoma: A Systematic Review. ( 27484231 )
2016
50
Coa89inhibition of miRNAa8921 and miRNAa89221 induces apoptosis by enhancing the p53a89mediated expression of proa89apoptotic miRNAs in laryngeal squamous cell carcinoma. ( 27035337 )
2016

Variations for Laryngitis

Expression for Laryngitis

Search GEO for disease gene expression data for Laryngitis.

Pathways for Laryngitis

Pathways related to Laryngitis according to GeneCards Suite gene sharing:

(show top 50) (show all 70)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.42 FGF2 IL1A IL1B IL6 TGFB1 TNF
2
Show member pathways
13.37 ATP4A IL1A IL1B IL6 TGFB1 TNF
3
Show member pathways
13.31 FGF2 IL1A IL1B IL6 TGFB1 TNF
4
Show member pathways
13.27 FGF2 IL1A IL1B IL6 TGFB1 TNF
5
Show member pathways
13.21 FGF2 IL1A IL1B IL6 TGFB1 TNF
6
Show member pathways
12.88 IL1A IL1B IL6 TNF
7
Show member pathways
12.79 IL1B IL6 TGFB1 TNF
8
Show member pathways
12.79 IL1A IL1B IL6 TGFB1 TNF
9
Show member pathways
12.71 IL1A IL1B IL6 TNF
10 12.65 FGF2 IL1A IL1B TGFB1 TNF
11
Show member pathways
12.54 IL1A IL1B IL6 TGFB1 TNF
12
Show member pathways
12.53 FGF2 IL1B IL6 TNF
13
Show member pathways
12.53 FGF2 IL1A IL1B IL6 TGFB1 TNF
14
Show member pathways
12.38 IL1A IL1B IL6 TGFB1 TNF
15 12.33 IL6 TGFB1 TNF
16
Show member pathways
12.25 IL1B IL6 TNF
17
Show member pathways
12.25 IL1A IL1B IL6 TNF
18
Show member pathways
12.24 IL1A IL1B TGFB1 TNF
19 12.22 FGF2 TGFB1 TNF
20 12.16 IL1A IL1B IL6 TGFB1 TNF
21 12.15 IL1A IL1B IL6 TNF
22
Show member pathways
12.13 IL1A IL1B IL6 TNF
23
Show member pathways
12.12 IL1B IL6 TNF
24 12.12 IL6 TGFB1 TNF
25
Show member pathways
12.1 FGF2 TGFB1 TNF
26 12.04 IL1A IL1B TNF
27 12.02 FGF2 IL6 TGFB1
28 12.02 IL1A IL1B TGFB1 TNF
29 12.01 IL6 TGFB1 TNF
30 11.92 IL1B IL6 TNF
31 11.92 IL1A IL1B IL6 TGFB1
32
Show member pathways
11.92 IL1B IL6 TGFB1 TNF
33
Show member pathways
11.89 IL1B IL6 TGFB1
34 11.87 IL1A IL1B IL6 TNF
35 11.86 FGF2 IL6 TGFB1
36 11.86 IL1B IL6 TGFB1 TNF
37 11.85 IL1A IL1B IL6 TGFB1 TNF
38 11.81 IL1A IL1B IL6
39 11.74 IL1A IL1B IL6 TNF
40 11.72 IL1B IL6 TGFB1 TNF
41 11.72 IL1A IL1B IL6 TGFB1 TNF
42 11.71 IL6 TGFB1 TNF
43
Show member pathways
11.62 IL1A IL1B IL6 TNF
44 11.61 IL1A IL1B IL6 TGFB1 TNF
45 11.6 IL1B IL6 TNF
46 11.53 IL1B TGFB1 TNF
47 11.53 FGF2 IL6 TGFB1
48 11.53 IL1A IL1B IL6
49 11.49 IL1A IL1B IL6 TNF
50 11.49 FGF2 IL1A IL1B IL6 TGFB1 TNF

GO Terms for Laryngitis

Cellular components related to Laryngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 FGF2 IL1A IL1B IL6 TGFB1 TNF
2 extracellular space GO:0005615 9.17 ATP4A FGF2 IL1A IL1B IL6 TGFB1

Biological processes related to Laryngitis according to GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.98 IL1A IL1B IL6 TGFB1
2 positive regulation of transcription from RNA polymerase II promoter GO:0045944 9.97 FGF2 IL1A IL1B IL6 TGFB1 TNF
3 positive regulation of transcription, DNA-templated GO:0045893 9.96 FGF2 IL1B IL6 TGFB1 TNF
4 regulation of cell proliferation GO:0042127 9.9 IL6 TGFB1 TNF
5 leukocyte migration GO:0050900 9.9 IL1B TGFB1 TNF
6 MAPK cascade GO:0000165 9.9 FGF2 IL1B TGFB1 TNF
7 positive regulation of protein phosphorylation GO:0001934 9.88 IL1B TGFB1 TNF
8 immune response GO:0006955 9.88 HRH2 IL1A IL1B IL6 TNF
9 positive regulation of cell proliferation GO:0008284 9.87 FGF2 IL6 TGFB1
10 cytokine-mediated signaling pathway GO:0019221 9.87 IL1A IL1B IL6
11 positive regulation of angiogenesis GO:0045766 9.85 FGF2 IL1A IL1B
12 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.84 IL1B IL6 TNF
13 activation of MAPK activity GO:0000187 9.84 FGF2 IL1B TNF
14 wound healing GO:0042060 9.82 FGF2 IL6 TGFB1
15 positive regulation of protein kinase B signaling GO:0051897 9.82 IL6 TGFB1 TNF
16 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.81 FGF2 IL6 TGFB1 TNF
17 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.8 IL6 TGFB1 TNF
18 cellular response to organic cyclic compound GO:0071407 9.79 IL1B TGFB1 TNF
19 positive regulation of MAP kinase activity GO:0043406 9.77 FGF2 TGFB1 TNF
20 positive regulation of protein secretion GO:0050714 9.74 IL1A TGFB1
21 regulation of angiogenesis GO:0045765 9.74 FGF2 IL6
22 cellular response to dexamethasone stimulus GO:0071549 9.74 IL6 TGFB1
23 digestive tract development GO:0048565 9.73 HRH2 TGFB1
24 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.73 IL1A IL1B
25 negative regulation of mitotic cell cycle GO:0045930 9.73 TGFB1 TNF
26 positive regulation of phagocytosis GO:0050766 9.73 IL1B TNF
27 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.73 FGF2 TGFB1
28 positive regulation of cytokine secretion GO:0050715 9.72 IL1A TNF
29 protein import into nucleus, translocation GO:0000060 9.72 TGFB1 TNF
30 positive regulation of interleukin-8 production GO:0032757 9.72 IL1B TNF
31 positive regulation of mitotic nuclear division GO:0045840 9.72 IL1A IL1B
32 negative regulation of fat cell differentiation GO:0045599 9.72 IL6 TGFB1 TNF
33 positive regulation of protein complex assembly GO:0031334 9.71 TGFB1 TNF
34 negative regulation of myoblast differentiation GO:0045662 9.71 TGFB1 TNF
35 positive regulation of blood vessel endothelial cell migration GO:0043536 9.71 FGF2 TGFB1
36 positive regulation of NF-kappaB import into nucleus GO:0042346 9.71 IL1B TNF
37 positive regulation of histone acetylation GO:0035066 9.71 IL1B TGFB1
38 negative regulation of blood vessel endothelial cell migration GO:0043537 9.7 FGF2 TGFB1
39 positive regulation of nitric oxide biosynthetic process GO:0045429 9.7 IL1B IL6 TNF
40 negative regulation of lipid catabolic process GO:0050995 9.69 IL1B TNF
41 positive regulation of chemokine production GO:0032722 9.69 IL6 TNF
42 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.69 IL1B TNF
43 hyaluronan catabolic process GO:0030214 9.68 FGF2 TGFB1
44 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.68 IL1B TNF
45 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.68 IL1B TNF
46 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.67 IL1A IL1B
47 positive regulation of chemokine biosynthetic process GO:0045080 9.66 IL1B TNF
48 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.65 IL1A IL1B
49 negative regulation of lipid storage GO:0010888 9.65 IL6 TNF
50 inflammatory response GO:0006954 9.65 IL1A IL1B IL6 TGFB1 TNF

Molecular functions related to Laryngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.33 FGF2 IL6 TGFB1
2 cytokine activity GO:0005125 9.1 FGF2 IL1A IL1B IL6 TGFB1 TNF
3 interleukin-1 receptor binding GO:0005149 8.96 IL1A IL1B

Sources for Laryngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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