MCID: LRY002
MIFTS: 17

Laryngostenosis malady

Categories: Respiratory diseases, Oral diseases

Aliases & Classifications for Laryngostenosis

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Aliases & Descriptions for Laryngostenosis:

Name: Laryngostenosis 10 12 36 65
 
Stenosis of Larynx 10

Classifications:



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Disease Ontology10 DOID:11527
ICD1027 J38.6
ICD9CM29 478.74
SNOMED-CT59 195864007, 75547007
MeSH36 D007829
NCIt42 C79608
UMLS65 C0023075

Summaries for Laryngostenosis

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MalaCards based summary: Laryngostenosis, also known as stenosis of larynx, is related to recurrent corneal erosion, and has symptoms including stridor An important gene associated with Laryngostenosis is FOXL2 (Forkhead Box L2). Affiliated tissues include lung.

Related Diseases for Laryngostenosis

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Diseases related to Laryngostenosis via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1recurrent corneal erosion8.9CTSB, FOXL2, ZBED1

Comorbidity relations with Laryngostenosis via Phenotypic Disease Network (PDN):


Hypertension, EssentialRespiratory Failure
Heart DiseaseBronchitis

Symptoms for Laryngostenosis

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UMLS symptoms related to Laryngostenosis:


stridor

Drugs & Therapeutics for Laryngostenosis

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Drugs for Laryngostenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Nucleic Acid Synthesis Inhibitors3836
2Mitomycins219
3Antibiotics, Antitubercular5971
4Anti-Bacterial Agents9140
5Alkylating Agents3582

Interventional clinical trials:

idNameStatusNCT IDPhase
1Clinical Trial of Stem Cell Based Tissue Engineered Laryngeal ImplantsRecruitingNCT01977911Phase 1, Phase 2
2Study of Mitomycin-C Application in Laryngotracheal StenosisRecruitingNCT01523275
3Treatment Alternatives in iSGS (NoAAC PR-02 Study)RecruitingNCT02481817
4Functional Modeling of the Pediatric AirwayEnrolling by invitationNCT01690078

Search NIH Clinical Center for Laryngostenosis


Cochrane evidence based reviews: laryngostenosis

Genetic Tests for Laryngostenosis

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Anatomical Context for Laryngostenosis

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MalaCards organs/tissues related to Laryngostenosis:

33
Lung

Animal Models for Laryngostenosis or affiliated genes

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Publications for Laryngostenosis

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Articles related to Laryngostenosis:

idTitleAuthorsYear
1
Severe feeding problems and congenital laryngostenosis in a patient with 3q23 deletion. (9266197)
1997
2
Three cases of congenital laryngostenosis with different etiologies. (18885519)
1948
3
OPERATIVE RELIEF OF LARYNGOSTENOSIS. (17865603)
1927

Variations for Laryngostenosis

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Expression for genes affiliated with Laryngostenosis

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Search GEO for disease gene expression data for Laryngostenosis.

Pathways for genes affiliated with Laryngostenosis

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GO Terms for genes affiliated with Laryngostenosis

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Sources for Laryngostenosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet